Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.1320
J. Tarrega Camarasa, I. Castillo Sánchez, J. Bruguet González, Y. Galea Colón, N. Angrill Sellés, E. Barbeta Sánchez
{"title":"Clinical impact of out-of-ICU non-invasive respiratory support in patients with COVID-19 related pneumonia","authors":"J. Tarrega Camarasa, I. Castillo Sánchez, J. Bruguet González, Y. Galea Colón, N. Angrill Sellés, E. Barbeta Sánchez","doi":"10.1183/13993003.congress-2022.1320","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.1320","url":null,"abstract":"","PeriodicalId":289883,"journal":{"name":"02.01 - Acute critical care","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130466468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.1862
L. Cornejo-Cornejo, A. Orea-Tejeda, D. González-Islas, J. Marquez-Cordero, A. Rios-Pereda, J. Aguilar-Meza, M. Salvatierra-Escobar, I. Lopez-Vazquez, C. Sánchez-Moreno, L. Hernández-Urquieta, A. Loaeza-Roman, J. Garcia-Hernandez, Y. Debray-Garcia, M. Sierra-Vargas, G. Aztatzi-Aguilar
{"title":"Serum markers of endothelial dysfunction and invasive mechanical ventilation in COVID-19","authors":"L. Cornejo-Cornejo, A. Orea-Tejeda, D. González-Islas, J. Marquez-Cordero, A. Rios-Pereda, J. Aguilar-Meza, M. Salvatierra-Escobar, I. Lopez-Vazquez, C. Sánchez-Moreno, L. Hernández-Urquieta, A. Loaeza-Roman, J. Garcia-Hernandez, Y. Debray-Garcia, M. Sierra-Vargas, G. Aztatzi-Aguilar","doi":"10.1183/13993003.congress-2022.1862","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.1862","url":null,"abstract":"","PeriodicalId":289883,"journal":{"name":"02.01 - Acute critical care","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126531271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.1148
Y. Tao, W. Han
{"title":"Predictive value of ultrasonic diaphragm thickening score combined with P0.1 in patients with mechanical ventilation","authors":"Y. Tao, W. Han","doi":"10.1183/13993003.congress-2022.1148","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.1148","url":null,"abstract":"","PeriodicalId":289883,"journal":{"name":"02.01 - Acute critical care","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125145727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.3520
J. Alqahtani, M. Alahmari, I. Aldraiwiesh, A. Alamoudi, N. Alotaibi, A. Ghazwani, A. Aldhahir, S. Alghamdi, A. Alqahtani, J. Sreedharan, S. Alrabeeah
{"title":"Early mobilisation of mechanically ventilated patients in the intensive care units: results of a Saudi-wide national survey","authors":"J. Alqahtani, M. Alahmari, I. Aldraiwiesh, A. Alamoudi, N. Alotaibi, A. Ghazwani, A. Aldhahir, S. Alghamdi, A. Alqahtani, J. Sreedharan, S. Alrabeeah","doi":"10.1183/13993003.congress-2022.3520","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.3520","url":null,"abstract":"","PeriodicalId":289883,"journal":{"name":"02.01 - Acute critical care","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130741774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.157
I. Adejumo, M. R. Ali, M. Sovani, D. E. Shaw
{"title":"Use of awake prone positioning in acute COVID-19","authors":"I. Adejumo, M. R. Ali, M. Sovani, D. E. Shaw","doi":"10.1183/13993003.congress-2022.157","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.157","url":null,"abstract":"","PeriodicalId":289883,"journal":{"name":"02.01 - Acute critical care","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134474346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.1164/ajrccm-conference.2022.205.1_MeetingAbstracts.A5627
M. R. Gabitan, S. Ganangan
Introduction: High Flow Nasal Cannula (HFNC) enabled us to treat Acute Respiratory Distress Syndrome (ARDS) successfully on subsets of patients with COVID 19 without requiring invasive ventilatory support and with low mortality. Cautious use of HFNC is required to closely monitor the response in those patients with ARDS who develop clinical signs of respiratory failure. Currently the use of HFNC in Acute Hypoxemic Respiratory Failure is not well established due to conflicting studies. Several guidelines did not specify clear recommendations who is indicated and who will benefit on HFNC. Therefore the potential use of HFNC to provide an fi02 of up to 100% at shunt fraction of 0.1-0.3 may provide a significant increase in Pa02/fio2 ratio to correct the hypoxemia brought by ARDS but theoretically unclear with shunt fraction > 0.4. Objectives: This study investigated the initial shunt fraction as a parameter to determine if HFNC will benefit a specific group of patients to predict who will benefit from HFNC, prevent delayed intubations and consequently conserve resources. Methods: This was a retrospective, cohort study. Total of 205 Covid19 critical patients initially on HFNC admitted from July 1, 2020 to July 31, 2021 were included. Results: Forty-seven patients (22.9%) showed improved oxygenation and were successfully withdrawn from HFNC. In the binary logistic regression analysis, factors affecting mortality showed that age was the only variable predictive of in-hospital all-cause mortality. In the factors affecting intubation, logistic regression revealed greater shunt fraction would increase the odds of being intubated. Patients who have 30-40% shunt fraction had 3.8 times higher odds of being intubated and having a shunt fraction of >40% had 3.5 times the odds of being intubated in comparison with shunt fraction of <30%. Conclusions: HFNC has low success rate in covid19 critical patients but significantly showed benefit in those with shunt fraction <30%. Additionally, this study was not able to show the benefit of HFNC in terms of mortality and length of hospital stay. Shunt fraction is still worthwhile to use as a gauge but should be combined with clinical judgment and/or in conjunction with other parameters.
{"title":"The Utility of Estimating the Shunt Fraction of Critical Patients with COVID-19 in determining the outcome of High Flow Nasal Cannula at Lung Center of the Philippines, a pilot study.","authors":"M. R. Gabitan, S. Ganangan","doi":"10.1164/ajrccm-conference.2022.205.1_MeetingAbstracts.A5627","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_MeetingAbstracts.A5627","url":null,"abstract":"Introduction: High Flow Nasal Cannula (HFNC) enabled us to treat Acute Respiratory Distress Syndrome (ARDS) successfully on subsets of patients with COVID 19 without requiring invasive ventilatory support and with low mortality. Cautious use of HFNC is required to closely monitor the response in those patients with ARDS who develop clinical signs of respiratory failure. Currently the use of HFNC in Acute Hypoxemic Respiratory Failure is not well established due to conflicting studies. Several guidelines did not specify clear recommendations who is indicated and who will benefit on HFNC. Therefore the potential use of HFNC to provide an fi02 of up to 100% at shunt fraction of 0.1-0.3 may provide a significant increase in Pa02/fio2 ratio to correct the hypoxemia brought by ARDS but theoretically unclear with shunt fraction > 0.4. Objectives: This study investigated the initial shunt fraction as a parameter to determine if HFNC will benefit a specific group of patients to predict who will benefit from HFNC, prevent delayed intubations and consequently conserve resources. Methods: This was a retrospective, cohort study. Total of 205 Covid19 critical patients initially on HFNC admitted from July 1, 2020 to July 31, 2021 were included. Results: Forty-seven patients (22.9%) showed improved oxygenation and were successfully withdrawn from HFNC. In the binary logistic regression analysis, factors affecting mortality showed that age was the only variable predictive of in-hospital all-cause mortality. In the factors affecting intubation, logistic regression revealed greater shunt fraction would increase the odds of being intubated. Patients who have 30-40% shunt fraction had 3.8 times higher odds of being intubated and having a shunt fraction of >40% had 3.5 times the odds of being intubated in comparison with shunt fraction of <30%. Conclusions: HFNC has low success rate in covid19 critical patients but significantly showed benefit in those with shunt fraction <30%. Additionally, this study was not able to show the benefit of HFNC in terms of mortality and length of hospital stay. Shunt fraction is still worthwhile to use as a gauge but should be combined with clinical judgment and/or in conjunction with other parameters.","PeriodicalId":289883,"journal":{"name":"02.01 - Acute critical care","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134549921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.4435
C. Autilio, P. Losada-Oliva, D. Sánchez Ortiz, Á. Mingote, R. Castejón Díaz, G. Hernandez, G. Díaz, M. Echaide, C. Salas, J. A. Vargas, J. Pérez-Gil
{"title":"Changes in surface activity of lung surfactant and bronchoalveolar cell profile upon COVID-19-related Acute Respiratory Distress Syndrome","authors":"C. Autilio, P. Losada-Oliva, D. Sánchez Ortiz, Á. Mingote, R. Castejón Díaz, G. Hernandez, G. Díaz, M. Echaide, C. Salas, J. A. Vargas, J. Pérez-Gil","doi":"10.1183/13993003.congress-2022.4435","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.4435","url":null,"abstract":"","PeriodicalId":289883,"journal":{"name":"02.01 - Acute critical care","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122298509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.1241
R. S. Bhingardeve, S. Mante, N. S. Ajwani, S. Thorve, S. R. Waghmare, J. P. Nair
{"title":"Outcome of patients admitted in Covid ICU during first wave and second wave in Mumbai Tertiary Hospital","authors":"R. S. Bhingardeve, S. Mante, N. S. Ajwani, S. Thorve, S. R. Waghmare, J. P. Nair","doi":"10.1183/13993003.congress-2022.1241","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.1241","url":null,"abstract":"","PeriodicalId":289883,"journal":{"name":"02.01 - Acute critical care","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122903323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.1183/13993003.congress-2022.1663
Á. Schranc, J. Diaper, R. Südy, F. Peták, W. Habre, G. Albu
{"title":"Assessment of lung recruitment with continuous negative extrathoracic pressure after one-lung ventilation: an experimental investigation","authors":"Á. Schranc, J. Diaper, R. Südy, F. Peták, W. Habre, G. Albu","doi":"10.1183/13993003.congress-2022.1663","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.1663","url":null,"abstract":"","PeriodicalId":289883,"journal":{"name":"02.01 - Acute critical care","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132134385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}