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The Medicinal Plants Traditionally Used Against Cardiovascular Diseases In Türkiye 我国传统上用于治疗心血管疾病的药用植物
Pub Date : 2023-06-20 DOI: 10.53811/ijtcmr.1232190
Meltem Güleç, Zeynep Büşra Erarslan, Ş. Kültür
Since time immemorial humankind benefits from plants as nutritient, medicine, cosmetic or to make tools and shelters for itself. Through history, traditional knowledge was gathered by trial-and-error method, practices were developed and sustained. It has been passed on from generation to generation to reach our day. This study aims to gather information on medicinal plants used traditionally against cardiovascular diseases in Turkey before it is lost forever. The library of Istanbul University being in the first place, the approachable sources has been scanned throughly. Plants’ scientific name, Turkish name, family, used parts, method of uses and the effects has been put together in a table. As a result, we composed a report of 129 plants of 43 families used for cardiovascular diseases. It has been concluded that of these, the most outstanding herbs are Crataegus monogyna Jacq., Lavandula stoechas L., Melissa officinalis L., Tribulus terrestris L., Urtica dioica L. and Viscum album L. Rosaceae, Lamiaceae and Asteraceae were the most used plant families. It has been detected that the people mostly benefit from the the leaves, aerial parts, fruit and flowers of medicinal plants as infusion or decoction. Although the biological activity studies on the plants most used by the people support the use in cardiovascular diseases, more studies are needed to provide scientific evidence to folklore use, especially for L. stoechas. It is thought that this study may be a resource for the development of future herbal medicines or treatments.
自古以来,人类就从植物中获得营养、药物、化妆品或为自己制造工具和住所。纵观历史,传统知识是通过试错法收集的,实践得到发展和维持。它代代相传,直到我们今天。这项研究旨在收集土耳其传统上用于治疗心血管疾病的药用植物的信息,以免这些植物永远消失。首先是伊斯坦布尔大学的图书馆,对可接近的资源进行了全面扫描。将植物的学名、土耳其语名、科、使用部位、使用方法和效果放在一个表格中。结果,我们撰写了43科129种用于心血管疾病的植物的报告。在这些草药中,最杰出的草药是山楂。利用最多的植物科为蔷薇科、灯叶科和菊科。人们已经发现,人们主要受益于药用植物的叶子、地上部分、果实和花朵作为冲剂或汤剂。虽然对人们最常用的植物的生物活性研究支持其在心血管疾病中的应用,但还需要更多的研究来为民间使用提供科学证据,特别是对白桦的使用。认为本研究可能为未来草药或治疗方法的开发提供资源。
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引用次数: 0
The Relationship Between CAM Methods which Pregnant Women Plan to Apply in Order to Reduce Their Pain in Childbirth and Fear of Childbirth and Childbirth Self-Efficacy 孕妇为减轻分娩疼痛、分娩恐惧和分娩自我效能感而计划采用的CAM方法的关系
Pub Date : 2023-03-27 DOI: 10.53811/ijtcmr.1208224
Sumeyye Barut, Esra Karataş Okyay
Objective: In the study, it was aimed to determine the relationship between CAM methods which pregnant women planned to apply in order to reduce their pain in childbirth and fear of childbirth and childbirth self-efficacy. Material-Method: The study was conducted in a cross-sectional design. It was completed with 455 pregnant women who met the inclusion criteria and did not have any risks related to their pregnancy. The study data were collected through Identifying Information Form, which also aimed to determine CAM methods planned to be used, The Wijma Delivery Expectancy/Experience Questionnaire (W-DEQ) Version A, and Childbirth Self-Efficacy Inventory. In the comparison of CAM users and non-users according to their identifying characteristics, Chi-square test was used for categorical variables. In the comparison between the participants’ W-DEQ A, CBSEI total scale mean scores and subscale mean scores and CAM methods they planned to use in childbirth to reduce their pain, Mann-Whitney U test was employed. Results: In the study, it was determined that the pregnant women planned to use mind-body based CAM methods by 31.4%, manipulative and body-based methods by 25, biologically based methods by 1.1%, energy therapy methods by 0.9%, and alternative medicine methods by 0.7%. It was also found that the pregnant women planned to use methods such as praying (n=88), listening to music (n=27), yoga (n=11), breathing exercise (n=10), and massage (n=8) the most, respectively. In addition, it was determined that there was a significant difference between CBSEI efficacy and outcome expectancy subscales mean scores and CBSEI total scale mean score of the pregnant women who did not plan to apply CAM methods to reduce their labor pain compared to those who planned to use these methods. Conclusion: It was found in the study that the pregnant women planned to use mind-body based methods the most in order to reduce their pain in childbirth. The use of other methods was limited. It was also determined that there was no significant difference between the groups in terms of fear of childbirth according to their planning to use CAM methods to reduce their pain in childbirth, and that childbirth self-efficacy levels of those who planned to use CAM methods were significantly low.
目的:在本研究中,旨在确定孕妇为减少分娩疼痛和分娩恐惧而计划采用的CAM方法与分娩自我效能感之间的关系。材料-方法:采用横断面设计。455名符合纳入标准且没有任何与妊娠相关的风险的孕妇完成了这项研究。通过识别信息表收集研究数据,确定计划使用的CAM方法,Wijma分娩期望/体验问卷(W-DEQ) A版和分娩自我效能量表。在根据识别特征对CAM使用者和非使用者进行比较时,分类变量采用卡方检验。在比较被试的W-DEQ A、CBSEI总量表平均分和亚量表平均分,以及她们计划在分娩中使用的减轻疼痛的CAM方法时,采用Mann-Whitney U检验。结果:在研究中,孕妇计划采用身心为基础的CAM方法占31.4%,手法和身体为基础的方法占25%,生物为基础的方法占1.1%,能量治疗方法占0.9%,替代医学方法占0.7%。研究还发现,孕妇计划分别使用祈祷(n=88)、听音乐(n=27)、瑜伽(n=11)、呼吸运动(n=10)和按摩(n=8)等方法。此外,我们确定,与计划使用这些方法的孕妇相比,不打算使用CAM方法减轻分娩疼痛的孕妇的CBSEI疗效和结果期望亚量表平均得分和CBSEI总量表平均得分之间存在显著差异。结论:本研究发现,为减轻分娩疼痛,孕妇最倾向于采用心身方法。其他方法的使用是有限的。根据计划使用CAM方法减轻分娩疼痛的情况,确定两组之间在分娩恐惧方面没有显著差异,计划使用CAM方法的分娩自我效能水平明显较低。
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引用次数: 0
History of Traditional Medicine Practices in Sudan: REVIEW 苏丹传统医学实践的历史:回顾
Pub Date : 2023-03-27 DOI: 10.53811/ijtcmr.1200069
ABDALBASIT ADAM MARIOD, Haroun Elrasheed, Mohamed Ahmed Agab
The history of Sudanese traditional medicine is well-established and ancient since the civilization of Kush and Meroe, through the Islamic kingdoms in Sennar, Kordofan, and Darfur, up to the period of Turkish and English-Egyptian colonization, and the development of traditional medicine until it reached what it is now in Sudan from the spread of folk healers. Traditional medicine healers are those who practice medicine by genetics, experience, knowledge, and subjective experience. In this chapter, the most important traditional healing practices such as Alfaki, Alkaiy, All Basir, etc. have been highlighted throughout history.
苏丹传统医学的历史由来已久,从库什和梅罗文明开始,经过塞纳尔、科尔多凡和达尔富尔的伊斯兰王国,一直到土耳其和英国-埃及殖民时期,传统医学的发展直到民间治疗师的传播才发展到现在的苏丹。传统医学治疗师是那些通过基因、经验、知识和主观经验来行医的人。在这一章中,历史上最重要的传统治疗方法,如Alfaki, Alkaiy, All Basir等都得到了强调。
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引用次数: 0
Investigating the Astonishing Antimicrobial Potential of Papaya seeds against Salmonella spp and Candida albicans 调查木瓜种子对沙门氏菌和白色念珠菌惊人的抗菌潜力
Pub Date : 2023-03-27 DOI: 10.53811/ijtcmr.1249215
E. Oboh
Objective: This study focused on the in vitro antibacterial efficacy of papaya seed ethanolic and aqueous extracts against Salmonella spp. and Candida albicans. Material-Method: Dry seeds of Carica papaya were extracted with ethanol and hot water and tested for antimicrobial activity against Salmonella spp and Candida albicans using agar well diffusion method on Muller Hilton agar. Results: The study found that the extracts worked better against Salmonella spp than Candida albicans, however, ethanol extract was stronger against the isolates with inhibition zone diameter (IZD) ranging from 10 mm to 32 mm, compared to the aqueous extract which only had 4 mm to 9 mm zones at certain concentrations. Conclusion: The activity of Carica papaya seed extracts demonstrates that the seeds are as significant as other parts of the plant and provides a scientific basis for the seeds' use in the treatment of many ailments in the local community. The extracts were more effective against Salmonella spp., with the ethanol extract having the highest antibacterial activity, indicating that the components of papaya seeds are more soluble in organic solvents and had stronger bactericidal characteristics. As a result, extensive analyses of the bioactive chemicals in Carica papaya seeds and their modes of action are required to present a full picture
目的:研究木瓜籽醇提液和水提液对沙门氏菌和白色念珠菌的体外抗菌作用。材料-方法:用乙醇和热水提取番木瓜干种子,在Muller Hilton琼脂上采用琼脂孔扩散法检测番木瓜干种子对沙门氏菌和白色念珠菌的抑菌活性。结果:研究发现,乙醇提取物对沙门氏菌的抑菌效果优于白色念珠菌,但在一定浓度下,乙醇提取物的抑菌效果较好,抑菌区直径为10 ~ 32 mm,而水溶液提取物的抑菌区直径仅为4 ~ 9 mm。结论:番木瓜种子提取物的活性表明番木瓜种子与该植物的其他部分一样重要,为番木瓜种子在当地社区治疗多种疾病提供了科学依据。其中,乙醇提取物对沙门氏菌的抑菌活性最高,说明番木瓜种子的成分更易溶于有机溶剂,具有较强的杀菌特性。因此,需要对番木瓜种子中的生物活性化学物质及其作用方式进行广泛的分析,才能全面了解番木瓜的情况
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引用次数: 0
Association Between Pain Severity, Pain Beliefs, Pain Coping and Attitudes Towards Complementary and Alternative Treatments among Physical Therapy Patients 物理治疗患者疼痛程度、疼痛信念、疼痛应对与补充和替代治疗态度的关系
Pub Date : 2023-03-27 DOI: 10.53811/ijtcmr.1218300
Emel BAHADIR YILMAZ, Elvan E Ata
Objective: The study aimed to determine the correlation between pain severity, pain beliefs, pain coping, and attitudes toward complementary and alternative treatments among physical therapy patients. Methods: This cross-sectional and analytical was conducted in a physical therapy and rehabilitation hospital in north-eastern Turkey. The sample consisted of 150 physical therapy patients. Data were collected using Demographic Information Form, Pain Beliefs Questionnaire, Pain Coping Questionnaire, and Attitudes towards Complementary and Alternative Medicine Questionnaire. Spearman’s Correlation Analysis and Multiple Linear Regression Analysis were used in data analysis. Results: The study revealed that the patients had negative attitudes towards complementary (13.64 ± 4.00) and alternative medicine use (13.18 ± 4.14). The scores were moderate for the patients' psychological (18.62 ± 3.69) and organic belief (33.68 ± 5.17). A significant correlation was determined between patients’ attitudes towards complementary medical treatment and conventional medical treatment for pain (p=0.020). The patients had moderate pain intensity (5.70±2.44), and there was a significant correlation between pain intensity and attitudes towards alternative medicine (p=0.012). Conclusion: Physical therapy patients’ attitudes towards complementary and alternative medicine are associated with pain coping and severity. The patients should be educated to cope with pain and manage it by health professionals.
目的:探讨物理治疗患者疼痛严重程度、疼痛信念、疼痛应对与补充和替代治疗态度的相关性。方法:在土耳其东北部的一家物理治疗和康复医院进行了横断面分析。样本包括150名物理治疗患者。采用《人口统计信息表》、《疼痛信念问卷》、《疼痛应对问卷》和《补充与替代医学态度问卷》进行数据收集。数据分析采用Spearman相关分析和多元线性回归分析。结果:患者对辅助用药(13.64±4.00)和替代用药(13.18±4.14)持否定态度。心理(18.62±3.69)分、有机信念(33.68±5.17)分为中等。患者对补充医学治疗的态度与对常规医学治疗的态度有显著相关(p=0.020)。患者疼痛强度为中等(5.70±2.44),疼痛强度与替代医学态度有显著相关(p=0.012)。结论:物理治疗患者对补充和替代医学的态度与疼痛应对和严重程度有关。应由卫生专业人员教育患者如何处理和管理疼痛。
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引用次数: 0
Antioxidant, Antimicrobial and Phenolic Component Analysis of Some Edge Medicinal Plants 一些边缘药用植物的抗氧化、抗菌及酚类成分分析
Pub Date : 2023-03-24 DOI: 10.53811/ijtcmr.1233624
Sultan Ülger, Serpil Uğraş
Objective: The plants, which grow wild in the Eastern Anatolia Region and are known as kari (Arum elongatum;Ae) and mende (Chaerophyllum macrospermum;Cm), are used for treatment purposes such as pain reliever and wound healing properties. It is aimed to determine some biological properties of these plants, which are also used medicinally. Material-Method: Firstly, hexane(H), ethanol(E) and acetone(A) extracts of dried plants were prepared and antimicrobial activities of extracts against 13 indicator microorganisms were determined by agar well diffusion method. Antioxidant activities were determined by DPPH and ABTS analyses and the total phenolic component contents were determined by the Folin-Ciocalteu method. Results: The maximum extract yield was obtained in the ethanol extracts of the plants (AeE;10.4011% CmE;2.4898%), the minimum extract yield was obtained in the acetone extracts (AeA;0.8422% CmA;0.3510%). The hexane extract of A. elongatum has no inhibition activity against E. faecalis and L. monocytogenes, but it has inhibition activity against other indicator microorganisms. The other extracts of A. elongatum and all extracts of C. macrospermum were found to have inhibitory activity against all indicator microorganisms. Furthermore, the highest phenolic content was calculated as 54.60±0.486 µg mL-1 (AeE) and the lowest content as 3.47±0.001 µg mL-1 (CmA). As a result of the DPPH method the highest IC50 was calculated as 32.4140 µg mL-1 (CmH) and the lowest IC50 as 12.7876 µg mL-1 (AeA) and ABTS method the highest IC50 was calculated as 10.3203 µg mL-1 (CmE), and the lowest IC50 as 0.2744 µg mL-1 (CmA). Conclusion: These results show that the plant extracts have strong antimicrobial activity and antioxidant activity.
目的:这些植物生长在安纳托利亚东部地区,被称为kari (Arum elongatum;Ae)和mende (Chaerophyllum macrospermum;Cm),用于缓解疼痛和伤口愈合等治疗目的。目的是确定这些植物的一些生物学特性,这些特性也可用于药用。材料-方法:首先制备干燥植物的己烷(H)、乙醇(E)和丙酮(A)提取物,采用琼脂孔扩散法测定提取物对13种指示微生物的抑菌活性。采用DPPH和ABTS法测定其抗氧化活性,采用Folin-Ciocalteu法测定其总酚含量。结果:乙醇提取物(AeE;10.4011% CmE;2.4898%)得率最高,丙酮提取物(AeA;0.8422% CmA;0.3510%)得率最低。长藤己烷提取物对粪肠杆菌和单核增生乳杆菌无抑制作用,但对其他指示微生物有抑制作用。结果表明,长柄荆芥其他提取物和大精荆芥所有提取物对所有指示微生物均有抑制活性。此外,酚类物质含量最高为54.60±0.486µg mL-1 (AeE),最低为3.47±0.001µg mL-1 (CmA)。DPPH法最高IC50为32.4140µg mL-1 (CmH),最低IC50为12.7876µg mL-1 (AeA); ABTS法最高IC50为10.3203µg mL-1 (CmE),最低IC50为0.2744µg mL-1 (CmA)。结论:该植物提取物具有较强的抗菌活性和抗氧化活性。
{"title":"Antioxidant, Antimicrobial and Phenolic Component Analysis of Some Edge Medicinal Plants","authors":"Sultan Ülger, Serpil Uğraş","doi":"10.53811/ijtcmr.1233624","DOIUrl":"https://doi.org/10.53811/ijtcmr.1233624","url":null,"abstract":"Objective: The plants, which grow wild in the Eastern Anatolia Region and are known as kari (Arum elongatum;Ae) and mende (Chaerophyllum macrospermum;Cm), are used for treatment purposes such as pain reliever and wound healing properties. It is aimed to determine some biological properties of these plants, which are also used medicinally. \u0000Material-Method: Firstly, hexane(H), ethanol(E) and acetone(A) extracts of dried plants were prepared and antimicrobial activities of extracts against 13 indicator microorganisms were determined by agar well diffusion method. Antioxidant activities were determined by DPPH and ABTS analyses and the total phenolic component contents were determined by the Folin-Ciocalteu method. \u0000Results: The maximum extract yield was obtained in the ethanol extracts of the plants (AeE;10.4011% CmE;2.4898%), the minimum extract yield was obtained in the acetone extracts (AeA;0.8422% CmA;0.3510%). The hexane extract of A. elongatum has no inhibition activity against E. faecalis and L. monocytogenes, but it has inhibition activity against other indicator microorganisms. The other extracts of A. elongatum and all extracts of C. macrospermum were found to have inhibitory activity against all indicator microorganisms. Furthermore, the highest phenolic content was calculated as 54.60±0.486 µg mL-1 (AeE) and the lowest content as 3.47±0.001 µg mL-1 (CmA). As a result of the DPPH method the highest IC50 was calculated as 32.4140 µg mL-1 (CmH) and the lowest IC50 as 12.7876 µg mL-1 (AeA) and ABTS method the highest IC50 was calculated as 10.3203 µg mL-1 (CmE), and the lowest IC50 as 0.2744 µg mL-1 (CmA). \u0000Conclusion: These results show that the plant extracts have strong antimicrobial activity and antioxidant activity.","PeriodicalId":296263,"journal":{"name":"International Journal of Traditional and Complementary Medicine Research","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133827682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effects of Manual Therapy and Inspiratory Muscle Training on Respiratory Parameters in Young Adults with Postural Problems: A Randomized Controlled Trial 手工疗法和吸气肌训练对体位问题青年呼吸参数的影响:一项随机对照试验
Pub Date : 2022-12-13 DOI: 10.53811/ijtcmr.1185377
Şeyda Yildiz, Leyla Ataş Balci, Seçil Özkurt
Objective: It was aimed to compare the effects of manual therapy (MT) and Inspiratory Muscle Training (IMT) on respiratory functions and postural problems of young adults in this study. Material and Methods: Thirty-five volunteers were randomly allocated into IMT and MT groups. All participants received twenty minutes of IMT twice a week for four weeks. Eight sessions of manual therapy were applied to MT group in addition to IMT. Forced Expiratory Volume in 1 Second (FEV1), Forced Vital Capacity (FVC), FEV1/FVC ratio, Peak Expiratory Flow (PEF), forward head posture (FHP) and thoracic hyperkyphosis were evaluated before and after the treatments. Results: Although there were significant improvements in the FEV1, FVC, FEV1/FVC ratio and PEF scores of MT group (p0.05). The comparisons of post-treatment scores of the FEV1, FVC, FEV1/FVC ratio and PEF between the groups revealed the greater improvements in the MT group than IMT group (p
目的:比较手工疗法(MT)和吸气肌训练(IMT)对青壮年呼吸功能和体位问题的影响。材料与方法:35名志愿者随机分为IMT组和MT组。所有参与者每周两次接受20分钟的IMT,持续四周。MT组在IMT的基础上进行8次手工治疗。评估治疗前后1秒用力呼气量(FEV1)、用力肺活量(FVC)、FEV1/FVC比值、呼气峰流量(PEF)、前倾头位(FHP)和胸后凸过度。结果:MT组FEV1、FVC、FEV1/FVC比值、PEF评分均有显著改善(p0.05)。两组间FEV1、FVC、FEV1/FVC比值及PEF治疗后评分比较,MT组较IMT组改善明显(p < 0.05)
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引用次数: 0
Evaluation of Temporomandibular Joint Dysfunction in Patients with Chronic Neck Pain 慢性颈痛患者颞下颌关节功能障碍的评价
Pub Date : 2022-12-08 DOI: 10.53811/ijtcmr.1184011
Hazel Çelik Güzel, Ayça Araci, Emine Aslan Telci, A. Cimbiz
Objective: The aim of this study was to compare the presence of temporomandibular joint dysfunction (TMD) in individuals with and without chronic neck pain (CBA). Methods: The study included 41 subjects with neck pain and 41 subjects without neck pain. All participants; Temporomandibular Disorders Research Diagnostic Criteria (TMR) The amount of mouth opening and the presence of sound in TMJ movements, pain intensity on palpation of chewing muscles Visual Analog Scale (VAS), active joint movement of the cervical region (goniometer) and neck pain related disability status ( Neck Disability Indicator/NDI) was evaluated. Interventions: The results of our study showed that the pain intensity of the temporomandibular joint (TMJ) was significantly higher than the control group. The severity of pain felt during rest, activity (active mouth opening) and chewing in the study group was significantly higher than the control group (p
目的:本研究的目的是比较慢性颈痛(CBA)患者和非慢性颈痛患者颞下颌关节功能障碍(TMD)的存在。方法:选取41例颈部疼痛患者和41例非颈部疼痛患者。所有的参与者;颞下颌关节疾病研究诊断标准(TMR)评估颞下颌关节运动中张嘴量和声音的存在、咀嚼肌触诊疼痛强度、颈部关节活动度(测角仪)和颈部疼痛相关残疾状态(颈部残疾指标/NDI)。干预措施:我们的研究结果显示,颞下颌关节(TMJ)疼痛强度明显高于对照组。研究组在休息、活动(主动张口)和咀嚼时的疼痛程度明显高于对照组(p
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引用次数: 0
In Vitro Inhibitory Potential of Lawsonia inermis Extracts against Multidrug Resistant Clinically-relevant Bacteria: a Phytochemical, Quantitative Antimicrobial and Toxicological Assessment 刺槐提取物对多药耐药临床相关细菌的体外抑制潜力:植物化学、定量抗菌和毒理学评估
Pub Date : 2022-12-07 DOI: 10.53811/ijtcmr.1193807
M. Olaitan, B. Nwadike
Objective: Majority of the current antibiotics have become less effective due to widespread of multidrug-resistant microorganisms. Medicinal plants are promising candidates that could be used to manage this menace. Therefore, phytochemical, toxicological and antimicrobial potentiality of Lawsonia inermis extracts against MDR clinical bacteria were carried out. Material-Method: Henna leaf and seed were extracted by cold maceration technique using methanol and water and screened phytochemically. Eight MDR isolates, four of which are ESβL-producers were used for this study. In vitro antimicrobial efficacy and quantitative antimicrobial potency of extracts were estimated. MIC and MBC were determined using broth macrodilution technique. Cytotoxicity test was conducted using brine shrimp lethality assay and LC50 was determined. Results: The findings of this study revealed that aqueous leaf extract possesses maximum percentage yield of 25.58%. Tannins and phenolic compounds were detected in all extracts, while steroid was absent. Methanol seed extract showed the highest antimicrobial efficacy against all bacteria with 100 percent activity. The highest and lowest zones of inhibition were recorded at 30.0±0.00 and 10.0±0.00 mm, respectively. The zones of inhibition of extracts differed significantly. All extracts displayed highest activity index against the ESβL-producing Enterobacter aerogenes 196 that was isolated from wound with highest value at 4.28. Pseudomonas aeruginosa U109 showed maximum susceptibility index (93.75%); majority of MIC values recorded were within the range of 1.95-62.5 mg/mL. Cytotoxicity test of methanol and aqueous extracts displayed 10001000, respectively. Conclusion: Findings from this study elucidate the efficacy of Lawsonia inermis as a potential remedy to manage MDR-related infectious bacteria.
目的:由于耐多药微生物的广泛存在,目前大多数抗生素的疗效已经降低。药用植物是很有希望用来控制这种威胁的候选者。因此,本研究旨在探讨刺槐提取物对耐多药临床病原菌的植物化学、毒理学和抗菌潜力。材料-方法:采用甲醇和水冷浸技术提取指甲花叶和种子,并进行植物化学筛选。8株MDR菌株,其中4株产es β l。对其体外抑菌效果和定量抑菌效力进行了评价。MIC和MBC采用高汤稀释法测定。采用卤虾致死法进行细胞毒性试验,测定LC50。结果:叶水提物提取率最高可达25.58%。在所有提取物中均检测到单宁和酚类化合物,而不含类固醇。甲醇籽提取物对所有细菌的抑菌活性最高,达到100%。最高抑制区为30.0±0.00 mm,最低抑制区为10.0±0.00 mm。不同提取物的抑制区差异显著。所有提取物对产es β l的产气肠杆菌196的活性指数最高,为4.28。铜绿假单胞菌U109的敏感性指数最高,为93.75%;大多数记录的MIC值在1.95 ~ 62.5 mg/mL之间。甲醇和水提物的细胞毒性试验分别显示为10001000。结论:本研究的结果阐明了野月牙菌作为一种潜在的治疗耐多药相关感染细菌的疗效。
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引用次数: 0
Is There a Relation between The Lower Extremity Mechanics and Patellofemoral Pain Syndrome? 下肢力学与髌股疼痛综合征有关系吗?
Pub Date : 2022-12-05 DOI: 10.53811/ijtcmr.1186313
Bahar Kara, Aslı Yeral, Deniz Aslan, Guzin Kaya Aytutuldu, E. Develi, Ayça Aklar
Objective: It has been theorized that changes in the lower extremity mechanics may lead to develop Patellofemoral Pain (PFP) in the young population. The present study aims to investigate the effects of lower extremity mechanics on Patellofemoral Pain Syndrome in private university students. Material and Methods: Kujala Pain Score (KPS) of 400 Yeditepe University students ages of 18-30 years was performed. Students having a less or equal point of 85 in KPS (n=30) and healthy groups randomly selected in students with KPS=100 (n=30) were measured in terms of Feiss Line, navicular drop, subtalar angle, tibial torsion, knee valgus angle, Q angle in standing and supine position and hamstring tightness. Results: The prevalence of PFP among students was found to be 10.5%(n = 42). In case and control groups were found 2nd Pes Planus (PP) as 16 (%53,3) and 3 (%10) respectively. A statistically significant difference was found between groups in navicular drop, subtalar angle, tibial rotation, Q angle in supine and hamstring tightness (p-value
目的:从理论上讲,在年轻人中,下肢力学的改变可能导致髌骨股骨痛(PFP)的发生。本研究旨在探讨下肢力学对私立大学生髌股疼痛综合征的影响。材料与方法:对400名年龄在18 ~ 30岁的Yeditepe大学学生进行Kujala疼痛评分(KPS)。测量KPS小于或等于85点的学生(n=30)和KPS=100点随机选取的健康组(n=30)的Feiss线、舟状下垂、距下角、胫骨扭转、膝关节外翻角、站立和仰卧位Q角和腿筋松紧度。结果:学生PFP患病率为10.5%(n = 42)。病例组和对照组第2扁平足(PP)分别为16例(%53,3例)和3例(%10)。两组患者舟形落差、距下角、胫骨旋转、仰卧Q角、腘绳肌紧度差异均有统计学意义(p值)
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引用次数: 0
期刊
International Journal of Traditional and Complementary Medicine Research
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