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Gender difference in long-term effect of cardiac rehabilitation; data from CRAGE-extra study 心脏康复长期效果的性别差异;来自 CRAGE-extra 研究的数据
IF 2.3 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-06-01 DOI: 10.1016/j.ijcrp.2024.200273
Giulia Nicolaio , Samuele Baldasseroni , Maria Vittoria Silverii , Francesca Marchetti , Costanza Burgisser , Davide Montini , Francesco Orso , Alessandra Pratesi , Andrea Ungar , Niccolò Marchionni , Francesco Fattirolli

Introduction

The positive effect of cardiac rehabilitation (CR) is demonstrated in younger and older patients. However, it is quite debated whether the beneficial effect is similarly maintained in both genders during follow-up.

Aim

to determine if the improvement obtained after CR remained significant at 1-year follow-up in older population, testing the influence of gender on this outcome.

Methods

All patients aged 75+ years consecutively referred to Cardiac Rehabilitation outpatient Unit at Careggi University Hospital were screened for eligibility. All patients attended a CR program, based on 5-day-per-week aerobic training sessions for 4 weeks and they were evaluated at the end of CR at 6 and 12 months of follow-up.

Results

361 patients with a mean age 80.6 ± 4.4 years with a complete 1-year follow-up were enrolled in the study, 87.5 % of them had an acute coronary event, and 27.6 % were females. The increase in exercise capacity at the end of CR and at 1-year follow-up was statistically significant (VO2 peak: +8.7 % in males p < 0.001, +8.5 % in females p < 0.001; distance walked at 6-min test: +7.3 % in males p < 0.001, +10.2 % in females p < 0.001, respectively); the trajectory of exercise improvement at 6 and 12 months of FU was similar in men and women without significant decrease (VO2 peak-ml/kg/min: CR discharge vs 1 year FU = 15.2 vs 15,0 p: NS; distance walked-meters: CR discharge vs 1 year FU = 445.5 vs 440.6, p: NS) from end of CR to 1-year.

Conclusions

the improvement in exercise tolerance obtained with CR program is still maintained at 1-year FU without significant influence of gender in our very old population.

导言:心脏康复(CR)对年轻和老年患者都有积极作用。方法筛选所有连续转诊至凯瑞吉大学医院心脏康复门诊部的 75 岁以上患者。结果361名平均年龄为(80.6±4.4)岁、随访时间为1年的患者参加了研究,其中87.5%的患者曾发生过急性冠状动脉事件,27.6%为女性。在 CR 结束时和随访 1 年后,运动能力的提高具有显著的统计学意义(VO2 峰值:男性 +8.7 %,女性 +8.7 %,男性 +8.7 %,女性 +8.7 %):男性为 +8.7 % p < 0.001,女性为 +8.5 % p < 0.001;6 分钟测试步行距离:分别为男性 +7.3 % p < 0.001,女性 +10.2 % p < 0.001);男性和女性在 FU 6 个月和 12 个月时的运动改善轨迹相似,没有显著下降(VO2 峰值-ml/kg/min:CR 出院 vs FU 1 年 = 15.2 vs 15,0 p. NS;步行距离-米:CR 出院 vs FU 1 年 = 15.2 vs 15,0 p. NS;步行距离-米:CR 出院 vs FU 1 年 = 15.2 vs 15,0 p. NS):NS;步行距离-米:CR出院 vs 1年FU = 445.5 vs 440.6, p. NS):结论:在我们的高龄人群中,通过 CR 计划获得的运动耐量改善在 1 年的 FU 中仍能保持,性别没有显著影响。
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引用次数: 0
Comparison of atherosclerotic cardiovascular disease (ASCVD) and Framingham risk scores (FRS) in an Iranian population 伊朗人群动脉粥样硬化性心血管疾病 (ASCVD) 与弗雷明汉风险评分 (FRS) 的比较
IF 2.3 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-06-01 DOI: 10.1016/j.ijcrp.2024.200287
Matin Sepehrinia , Hossein Pourmontaseri , Mehrab Sayadi , Mohammad Mehdi Naghizadeh , Reza Homayounfar , Mojtaba Farjam , Azizallah Dehghan , Abdulhakim Alkamel

Background

Framingham risk score (FRS) and Atherosclerotic Cardiovascular Disease risk score (ASCVDrs) are widely used tools developed based on the American population. This study aimed to compare the ASCVDrs and FRS in an Iranian population.

Method

The participants of the Fasa Adult Cohort Study and the patients of the cardiovascular database of Vali-Asr Hospital of Fasa, aged 40–80 years, were involved in the present cross-sectional study. After excluding non-eligible participants, the individuals with a history of myocardial infarction or admission to the cardiology ward due to heart failure were considered high-risk, and the others were considered low-risk. The discriminative ability of FRS and ASCVDrs was evaluated and compared using receiver operating characteristic curve analysis. The correlation and agreement of ASCVDrs and FRS were tested using Cohen Kappa and Spearman.

Results

Finally, 8983 individuals (mean age:53.9 ± 9.5 y, 49.2 % male), including 1827 high-risk participants, entered the study. ASCVDrs detected a greater portion of participants as high-risk in comparison with FRS (28.7 % vs. 15.7 %). ASVD (AUC:0.794) had a higher discriminative ability than FRS (AUC:0.746), and both showed better discrimination in women. Optimal cut-off points for both ASCVDrs (4.36 %) and FRS (9.05 %) were lower than the original ones and in men. Compared to FRS, ASCVDrs had a higher sensitivity (79.3 % vs. 71.6 %) and lower specificity (64.5 % vs. 65.1 %). FRS and ASCVDrs had a moderate agreement (kappa:0.593,p-value<0.001) and were significantly correlated (Spearman:0.772,p-value<0.001).

Conclusions

ASCVDrs had a more accurate prediction of cardiovascular events and identified a larger number of people as high-risk in the Iranian population.

背景弗雷明汉风险评分(FRS)和动脉粥样硬化性心血管疾病风险评分(ASCVDrs)是根据美国人群开发的广泛使用的工具。本研究旨在比较 ASCVDrs 和 FRS 在伊朗人群中的应用情况。方法:本横断面研究的对象是法萨成人队列研究(Fasa Adult Cohort Study)的参与者和法萨瓦利-阿斯尔医院(Vali-Asr Hospital of Fasa)心血管数据库的患者,年龄在 40-80 岁之间。在排除不符合条件的参与者后,有心肌梗死病史或因心力衰竭入住心脏病病房的人被视为高危人群,其他人被视为低危人群。采用接收器操作特征曲线分析法对 FRS 和 ASCVDrs 的判别能力进行了评估和比较。结果最终有 8983 人(平均年龄:53.9 ± 9.5 岁,49.2% 为男性)参与了研究,其中包括 1827 名高风险参与者。与 FRS 相比,ASCVDs 检测出的高危人群比例更高(28.7% 对 15.7%)。ASVD(AUC:0.794)比 FRS(AUC:0.746)具有更高的判别能力,两者对女性的判别能力都更强。ASCVDrs(4.36%)和FRS(9.05%)的最佳临界点均低于原始临界点,且男性的临界点也低于原始临界点。与 FRS 相比,ASCVDrs 的灵敏度更高(79.3% 对 71.6%),特异性更低(64.5% 对 65.1%)。结论ASCVDrs能更准确地预测心血管事件,并能在伊朗人群中识别出更多的高危人群。
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引用次数: 0
Treatment of obesity with liraglutide in cardiovascular prevention: Case series by the “ITACARE-P Light-Heart Lab” working group 利拉鲁肽治疗肥胖症,预防心血管疾病:ITACARE-P轻型心脏实验室 "工作组的病例系列
IF 2.3 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-06-01 DOI: 10.1016/j.ijcrp.2024.200272
Francesco Maranta , Francesca Buffoli , Vittorio Giudici , Gabriella Malfatto , Alessandro Maloberti , Luigi Maresca , Bruno Passaretti , Anna Torri , Roberto Turato , Marco Ambrosetti
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引用次数: 0
Position paper ITACARE-P/FADOI on the referral from internal medicine to cardiac rehabilitation: Executive summary and factsheet ITACARE-P/FADOI关于从内科转诊到心脏康复的立场文件:执行摘要和概况介绍
IF 2.3 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-06-01 DOI: 10.1016/j.ijcrp.2024.200275
Marco Ambrosetti , Francesco Fattirolli , Paola Gnerre , Franco Mastroianni , Gian Francesco Mureddu , Francesco Dentali , Francesco Giallauria , Michele Meschi , Alessandra Pratesi , Matteo Ruzzolini , Elio Venturini

The Italian Association for Cardiovascular Rehabilitation and Prevention (ITACARE-P) and the Italian Federation of Associations of Hospital Doctors on Internal Medicine (FADOI) released a joint position paper to guide referrals of cardiovascular patients discharged from Internal Medicine (IM) wards to Cardiac Rehabilitation (CR) facilities. The document provides rationale and operative recommendations for appropriateness (i.e. qualifying diagnoses) and priority criteria to overcome the mismatch between potential demand and effective supply of CR programmes. In case of no-referral due to logistic barriers, the document recommends the adoption of best alternatives to CR for disability reduction, better prognosis, and improvement of quality of life. The joint position paper is also aimed to promote the consideration of IM as a potential stakeholder of CR.

意大利心血管康复与预防协会(ITACARE-P)和意大利医院内科医生协会联合会(FADOI)发布了一份联合立场文件,旨在指导从内科(IM)病房出院的心血管病人转诊至心脏康复(CR)机构。该文件就适当性(即合格诊断)和优先标准提供了理论依据和操作建议,以克服 CR 项目潜在需求与有效供应之间的不匹配。在因后勤障碍而无法转诊的情况下,文件建议采用 CR 的最佳替代方案,以减少残疾、改善预后和提高生活质量。联合立场文件还旨在促进将 IM 视为 CR 的潜在利益攸关方。
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引用次数: 0
41Bridging the gender gap in Cardiac Rehabilitation. The first step: The equal opportunities project 41 缩小心脏康复中的性别差距。第一步:平等机会项目
IF 2.3 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-06-01 DOI: 10.1016/j.ijcrp.2024.200268
Elisabetta Angelino

Women receive similar or greater benefits than men from Cardiac Rehabilitation (CR). However, they are less likely to participate. An integrated and gender-sensitive approach to cardiovascular disease is required to enhance the quality and experience of care for women with different cardiovascular issues throughout their lives.

The Italian Alliance for Cardiovascular Rehabilitation and Prevention (ITACARE-P) is committed to developing a gender-specific approach to CR that will more effectively meet the needs of both women and men.

女性从心脏康复(CR)中获得的益处与男性相似或更多。然而,她们参与的可能性较小。意大利心血管康复与预防联盟(ITACARE-P)致力于开发一种针对不同性别的心脏康复方法,以更有效地满足女性和男性的需求。
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引用次数: 0
Rehabilitation post pulmonary embolism: Preliminary data 肺栓塞后的康复治疗:初步数据
IF 2.3 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-06-01 DOI: 10.1016/j.ijcrp.2024.200269
Michele Azzarito , Carmela Fabiano , Roberto Bellini , Matteo Ruzzolini
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引用次数: 0
Indicators of nutritional status and patient needs in cardiac rehabilitation 心脏康复中的营养状况和患者需求指标
IF 2.3 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-06-01 DOI: 10.1016/j.ijcrp.2024.200270
Letizia da Vico

Background

The prevalence and incidence of cardiovascular diseases significantly increase with age, and it is well-known that nutritional status affects the prognosis and treatment of these diseases. Therefore, evaluating nutritional status is essential for maintaining/regaining health. It is crucial to identify nutritional risk early, prevent and/or treat protein-energy malnutrition, and promote the modification of inappropriate dietary habits.

Methods

Nutritional screening represents the first step of access to the Nutrition Care Process (NCP) adopted and managed by the dietitian; this tool must be simple, inexpensive, accessible, accurate, efficient, and validated. A globally accepted standardized definition of malnutrition is necessary, and for this reason, the Global Leadership Initiative on Malnutrition (GLIM) criteria have been recently introduced.

The GLIM criteria, after confirming nutritional risk through screening, include both phenotypic and etiological criteria: to diagnose malnutrition, at least one of these must be present.

A less commonly performed phenotypic criterion is the assessment of muscle mass, which should be studied as a significant component of sarcopenia.

Conclusion

Greater attention to the identification and treatment of malnutrition would bring benefits to patients and ensure a saving in healthcare expenditure, but for this purpose, an implementation of clinical nutrition services is necessary.

背景心血管疾病的患病率和发病率随着年龄的增长而显著增加,众所周知,营养状况会影响这些疾病的预后和治疗。因此,评估营养状况对维持/恢复健康至关重要。方法营养筛查是营养师采用和管理营养护理程序(NCP)的第一步;这一工具必须简单、廉价、方便、准确、高效并经过验证。通过筛查确认营养风险后,GLIM 标准包括表型标准和病因标准:要诊断营养不良,必须至少具备其中一项标准。一个较少采用的表型标准是肌肉质量评估,应将其作为肌少症的一个重要组成部分进行研究。结论对营养不良的识别和治疗给予更多关注将为患者带来益处,并确保节省医疗开支,但为此目的,有必要实施临床营养服务。
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引用次数: 0
Emerging Lp(a)-Lowering therapies: Is muvalaplin a potential breakthrough? 降低脂蛋白(a)的新兴疗法:muvalaplin是一个潜在的突破口吗?
IF 2.3 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-06-01 DOI: 10.1016/j.ijcrp.2024.200262
Zeeshan Afzal , Sara Hira , Huili Cao
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引用次数: 0
Cardiac amyloidosis red flags: What all the cardiologist have to know 心脏淀粉样变性红旗:心脏病医生必须知道的事情
IF 2.3 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-06-01 DOI: 10.1016/j.ijcrp.2024.200271
Alessandro Maloberti , Claudio Ciampi , Francesco Politi , Saverio Fabbri , Francesco Musca , Cristina Giannattasio

Cardiac amyloidosis is becoming increasingly important among cardiologist and an early diagnosis is very important. Amyloidosis is a systemic disease and many cardiac and extracardiac elements (red flags) should raise the suspicion of the disease. Electrocardiographic and imaging techniques (such as echocardiography, cardiac magnetic resonance and scintigraphy) are useful tools to make a diagnosis together with the presence of orthopedic issues, peripheral neuropathy or plasma cell dyscrasia. Cardiac amyloidosis is also often associated with valvular disorder, heart failure or cardiomyopathy. Red flags are crucial to raise suspicion and reach an early diagnosis, in order to start a targeted treatment strategy that could change the patient's outcome. Indeed, in the last years four new drugs were approved to treat transthyretin amyloidosis.

心脏淀粉样变性在心脏病专家中的地位日益重要,早期诊断非常重要。淀粉样变性是一种全身性疾病,许多心脏和心脏外因素(红旗)都应引起对该疾病的怀疑。心电图和成像技术(如超声心动图、心脏磁共振和闪烁照相)以及骨科疾病、周围神经病变或浆细胞异常是诊断的有用工具。心脏淀粉样变性还常常伴有瓣膜病、心力衰竭或心肌病。红旗是引起怀疑和早期诊断的关键,以便开始有针对性的治疗策略,从而改变患者的预后。事实上,在过去几年中,已经有四种治疗转甲状腺素淀粉样变性病的新药获得批准。
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引用次数: 0
Emerging risks of microplastics and nanoplastics (MNPs): Is a silent threat for cardiovascular disease? 微塑料和纳米塑料(MNPs)的新风险:对心血管疾病的威胁是否无声无息?
IF 2.3 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-06-01 DOI: 10.1016/j.ijcrp.2024.200280
Zeeshan Afzal, Abdul Basit, Usama Habib, Mateen Aman, Muhammad Azim, Huili Cao
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引用次数: 0
期刊
International Journal of Cardiology Cardiovascular Risk and Prevention
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