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Postmortem forensic imaging: An essential tool in contentious cases 死后法医成像:在有争议的案件中必不可少的工具
Pub Date : 2018-01-01 DOI: 10.4103/WAJR.WAJR_35_17
N. Nwafor, C. Nwafor, J. Obafunwa, M. Ekpo
Background: Traditional autopsy (TA) is employed towards determining the cause and manner of death. Over the last decade, virtual autopsy (VA), involving the application of forensic imaging techniques have gained prominence and, with great precision in developed countries. Aim: This is to compare the findings at post-mortem using forensic imaging techniques and, those of TA. Materials and Methods: Post-mortem CT-Scan and MRI techniques were employed in the present case and for the first time in Nigeria, to identify the fatal injuries and determine their causation. The examination was done prior to the TA; the latter was done by a team of pathologists without the prior knowledge of the imaging findings. The results, using both methods, were subsequently compared. Results: Most of the VA and TA findings were the same except for the areas that were not readily accessible to the pathology team because of prior embalmment of the body. The inexperience of the radiologist in the area of post-mortem forensic imaging also contributed to the few discrepancies. Conclusion: This is the first virtopsy to be conducted in Nigeria and, with impressive results. The findings compare favourably with those of TA and, have the added advantage of identifying minor injuries that might easily be missed using TA method. Success is however hinged on the expertise of the forensic radiologist and forensic pathologist. While VA can be employed to solve the problems of religious opposition to TA, the cost of the former is astronomical.
背景:传统的尸检(TA)用于确定死亡原因和方式。在过去的十年里,涉及法医成像技术应用的虚拟尸检(VA)在发达国家获得了突出地位,并具有极高的精度。目的:比较使用法医成像技术和TA的尸检结果。材料和方法:本病例采用尸检CT扫描和MRI技术,并在尼日利亚首次采用,以确定致命损伤并确定其原因。检查在TA之前完成;后者是由一组病理学家在事先不了解成像结果的情况下完成的。随后对两种方法的结果进行了比较。结果:大多数VA和TA的发现是相同的,除了病理组由于之前对身体进行防腐处理而不容易接近的区域。放射科医生在死后法医成像领域缺乏经验也是造成少数差异的原因。结论:这是在尼日利亚进行的第一次virtopsy,结果令人印象深刻。这些发现与TA的结果相比是有利的,并且具有额外的优势,即使用TA方法识别可能容易遗漏的轻伤。然而,成功取决于法医放射科医生和法医病理学家的专业知识。虽然VA可以用来解决宗教反对TA的问题,但前者的成本是天文数字。
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引用次数: 2
Postirradiation white blood cell recovery in rats: Following single and double (repeated) X-ray exposure 大鼠照射后白细胞的恢复:单次和双次(重复)X射线照射后
Pub Date : 2018-01-01 DOI: 10.4103/WAJR.WAJR_30_17
Mohammed Sirage Ibrahim, Mathew G. Abubakar, N. Chigozie, Geoffrey Lunsti, Paul Bura
Purpose: This study aims at determining the effect of radiation on peripheral white blood cells (WBCs) and the time for their full recovery in Albino Wister Rats following single and double (repeated) X-ray exposure so that a safe period for repeated irradiation can conveniently be recommended for any radiographic examination. Materials and Methods: Twenty one healthy albino Wister Rats of aged between 2–4 month and weighing about 140–200 g were used for this study. They were divided into three Groups A, B, and C. Group B and C were irradiated with X-ray from a diagnostic X-ray machine. Group C was immediately irradiated again with the same exposure factors at about 3–4 min interval. Blood samples from both control and experimental groups (after irradiation) were collected through a period of 30 min to 7 days and subjected to standard hematologic examination to determine the WBC count and differential leukocytes count. Results: A sharp fall in WBC was observed in the single-exposed group 30 min following irradiation. This is however more pronounced in the double-exposed group. This fall persisted till 48 h after irradiation. The WBC count returned to normal on the 3rd and 4th day following irradiation for both experimental groups. The maximum repair and recovery recorded were 98.6% for single exposure and 95.9% for double exposure of the normal count. Conclusion: This study has presented that the recovery of an irradiated peripheral WBC is not 100% and that the effect is more remarkable in cells with double (repeated) irradiation. A safe period of at least 3–7 days should be allowed for the cells to recover from previous irradiation before an examination is repeated. This will serve as a guide to radiographers/radiologist in the management of patients who need follow-up examinations.
目的:本研究旨在确定辐射对Albino Wister大鼠单次和双次(重复)X射线照射后外周血白细胞(WBCs)的影响及其完全恢复的时间,以便在任何射线照相检查中方便地推荐重复辐射的安全期。材料和方法:21只健康的白化Wister大鼠,年龄在2-4个月之间,体重约140-200克,用于本研究。他们被分为A、B和C三组。B和C组用诊断X光机的X射线照射。C组立即以相同的暴露因子再次照射,间隔约3-4分钟。在30分钟至7天的时间内收集来自对照组和实验组(照射后)的血液样本,并进行标准血液学检查以确定WBC计数和差异白细胞计数。结果:照射30min后,单次照射组WBC明显下降。然而,这在双重暴露组中更为明显。这种下降一直持续到照射后48小时。两个实验组的WBC计数在照射后第3天和第4天恢复正常。记录的最大修复和恢复率为正常计数的单次暴露的98.6%和双次暴露的95.9%。结论:本研究表明,经照射的外周血白细胞的回收率不是100%,在双重(重复)照射的细胞中效果更显著。在重复检查之前,应允许细胞从先前的照射中恢复至少3-7天的安全期。这将作为放射技师/放射科医生管理需要后续检查的患者的指南。
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引用次数: 0
Interdisciplinary investigation of occurrence of diverticular disease among patients referred for barium enema and colonoscopy studies at Dr. George Mukhari Academic Hospital, Ga-Rankuwa, Pretoria, South Africa 在南非比勒陀利亚Ga-Rankuwa的Dr. George Mukhari学术医院进行钡灌肠和结肠镜检查的患者中憩室疾病发生的跨学科调查
Pub Date : 2018-01-01 DOI: 10.4103/WAJR.WAJR_44_17
J. Ozoh, M. Vally, Olakunle A Towobola
Background: Diverticular disease (DD) is believed to be a disease which is prevalent in developed countries. Contrary to this belief, DD has been reported with an increasing trend in prevalence in Africa for the past four decades. Objectives: The objective of this study was to highlight the increasing trend of DD and to corroborate barium enema findings obtained from Diagnostic Radiology Department, with colonoscopy results from the Surgery Department at Dr. George Mukhari Academic Hospital. Methods: Results for barium enema and colonoscopy investigations of all the patients referred over a 1-year period were retrospectively reviewed by two independent research groups; each of these groups was unaware of the research carried out in the Departments of Diagnostic Radiology and Surgery. Data from the records were analyzed with the Statistical Package for the Social Sciences (IBM SPSS, version 22.0), New York, USA, version 22.0. Results: Barium enema results of 166 patients were evaluated for DD, and out of these, 129 patients (77.7%) were negative, while 37 patients (22.3%) (95% confidence interval = 19.07–25.50) were positive. A review of 384 colonoscopy results also revealed positive evidence for 47 patients (13.5%) (95% confidence interval = 10.30–17.50) for DD and 337 patients (86.5%) were negative. The findings of barium enema and colonoscopy investigative studies were similar for female preponderance, diffuse pattern of distribution of DD and the mean age of patients. Conclusion: The two studies corroborate each other and have produced the highest number of diagnostic yield for DD in one year, in Africa.
背景:憩室病(DD)被认为是一种在发达国家普遍存在的疾病。与这种看法相反,据报道,在过去四十年中,DD在非洲的患病率呈上升趋势。目的:本研究的目的是强调DD的增加趋势,并证实诊断放射科的钡灌肠结果,以及Dr. George Mukhari学术医院外科的结肠镜检查结果。方法:由两个独立的研究小组回顾性分析1年内所有患者的钡灌肠和结肠镜检查结果;这些小组中的每一个都不知道在诊断放射学和外科进行的研究。使用美国纽约22.0版的Statistical Package for the Social Sciences (IBM SPSS, version 22.0)对记录中的数据进行分析。结果:166例患者钡灌肠检查DD,阴性129例(77.7%),阳性37例(22.3%)(95%可信区间= 19.07-25.50)。对384例结肠镜检查结果的回顾也显示47例(13.5%)患者(95%置信区间= 10.30-17.50)为DD阳性,337例(86.5%)为阴性。钡灌肠和结肠镜调查研究的结果在DD的女性优势、弥漫性分布模式和患者的平均年龄方面相似。结论:这两项研究相互印证,在非洲一年内DD的诊断率最高。
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引用次数: 1
Routine addition of diffusion-weighted imaging to pediatric brain imaging with acute presentation: An initial experience 常规添加弥散加权成像儿童脑成像急性表现:初步经验
Pub Date : 2018-01-01 DOI: 10.4103/WAJR.WAJR_27_17
S. Wahab, R. Khan, S. Siddiqui
Context: A number of disorders affecting the pediatric brain pose a diagnostic challenge. Magnetic resonance imaging (MRI) is widely accepted as a sensitive technique for the diagnosis of ischemia, encephalitis, and leukodystrophies. Conventional MR sequences used in routine practice include T1-weighted (T1-W), T2-weighted, and fluid-attenuation inversion recovery (FLAIR) sequences. However usually, the presentation in small children is confusing and presents a diagnostic challenge even after the use of these various MR sequences requiring repeated MRI examinations. Detecting pathological changes occurring at microenvironment level is vital for early diagnosis, effective treatment, and obviating the need of repeated MRI. Aims: The purpose of our study was to assess the additional role of diffusion-weighted imaging (DWI) in better detection of these various pathologies of brain. Settings and Design: This was a prospective study. Subjects and Methods: Thirty children of ages ranging from neonate to 12 years of age with various complaints of central nervous system involvement were evaluated with MRI brain within 72 h of initial clinical presentation. T1 and T2 spin-echo sequences FLAIR and postcontrast T1-W imaging were done. DWI was performed with echoplanar imaging using depth-resolved surface coil spectroscopy sequence. The lesions were evaluated on DWI and conventional sequences. The final diagnosis was established on the basis of clinical evaluation, electroencephalographic findings, imaging, cerebrospinal fluid analysis, serologic tests, and fatty acid evaluation in plasma assay. Statistical Analysis Used: This was a descriptive study. Results: The patients were divided into three groups. Group A included patients in whom DWI detected more lesions or showed a greater extent of lesions on apparent diffusion coefficient (ADC) map than conventional MRI. This group had 11 cases including 7 cases of ischemic encephalopathy, one case of adrenoleukodystrophy (ADL) showing increased extent of lesion with restricted diffusion at the advancing edge and 3 cases of viral encephalitis. In Group B, 12 cases had similar results in both DWI and conventional MRI imaging. Of these, 7 cases with no specific diagnosis and subsequent spontaneous recovery showed no lesion on both conventional and DWI; 5 cases showed equal extent and number of lesions on DWI; 1 case was diagnosed as ADL, 2 as viral encephalitis, and 2 as ischemic encephalopathy on final workup. In Group C, T2 and FLAIR showed more lesions than DWI and had 7 cases. 5 had normal ADC maps but 1–2 small hyperintense lesions on T2 and FLAIR imaging, while the remaining two diagnosed with ischemic encephalopathy had hyperintense areas on T2 and FLAIR sequences with associated ventricular enlargement and cortical atrophy while DWI revealed them to be T2 shine through areas with increased ADC value focally. The 5 cases with hyperintensity on T2 and FLAIR, but normal ADC maps were labeled as nonspecific whit
背景:许多影响儿童大脑的疾病对诊断提出了挑战。磁共振成像(MRI)被广泛认为是诊断脑缺血、脑炎和白细胞营养不良的敏感技术。常规实践中使用的常规MR序列包括T1加权(T1-W)、T2加权和流体衰减反演恢复(FLAIR)序列。然而,通常情况下,幼儿的表现令人困惑,即使在使用这些需要重复MRI检查的各种MR序列后,也会带来诊断挑战。检测微环境水平上发生的病理变化对于早期诊断、有效治疗和消除重复MRI的需要至关重要。目的:我们研究的目的是评估扩散加权成像(DWI)在更好地检测这些不同的大脑病理中的额外作用。设置和设计:这是一项前瞻性研究。受试者和方法:30名年龄从新生儿到12岁的儿童,在首次临床表现后72小时内,用MRI对其大脑进行评估。进行T1和T2自旋回波序列FLAIR和对比后T1-W成像。DWI采用深度分辨表面线圈光谱序列进行回声平面成像。根据DWI和常规序列对病变进行评估。最终诊断是根据临床评估、脑电图、影像学、脑脊液分析、血清学检查和血浆脂肪酸评估确定的。使用的统计分析:这是一项描述性研究。结果:将患者分为三组。A组包括DWI在表观扩散系数(ADC)图上检测到比传统MRI更多病变或病变程度更大的患者。该组有11例,其中7例为缺血性脑病,1例为肾上腺脑白质营养不良(ADL),病变范围增加,前进边缘扩散受限,3例为病毒性脑炎。在B组中,12例在DWI和常规MRI成像中具有相似的结果。其中,7例无特异性诊断且随后自发恢复的病例在常规和DWI上均未显示病变;5例DWI显示病变范围和数量相等;1例诊断为ADL,2例诊断为病毒性脑炎,2例最终诊断为缺血性脑病。在C组中,T2和FLAIR显示的病变比DWI多,有7例。5例ADC图正常,但在T2和FLAIR成像上有1-2个小的高信号病变,而其余两例被诊断为缺血性脑病的患者在T2和FLAIR序列上有高信号区域,并伴有心室增大和皮质萎缩,而DWI显示它们是T2,通过局灶性ADC值增加的区域发光。5例在T2和FLAIR上有高信号,但正常ADC图被标记为非特异性白质高信号。在研究期间,这些儿童既没有任何病变进展,也没有任何进一步的临床症状。结论:我们得出的结论是,DWI在检测早期病理变化方面比其他MR序列更敏感,即使在除缺血外的病毒性脑炎和脑白质营养不良的情况下也是如此。这也有助于在微观层面上更准确地描绘该区域。我们还能够从T2和FLAIR上的非特异性高信号中排除实际的病理学,在某些情况下DWI上也可以排除FLAIR。
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引用次数: 0
Occupational hazards among medical radiation workers 医疗放射工作人员的职业危害
Pub Date : 2018-01-01 DOI: 10.4103/WAJR.WAJR_1_17
P. Ogenyi, A. England, Yusuf Aliyu, Joseph Dlama, A. Hamza, R. Hamunyela, M. Dauda
Objectives: The objective of the study was to determine the prevalence of occupational hazards among medical radiation workers in Northern Nigeria and to assess the adequacy of existing occupational safety measures in the region. Materials and Methods: A prospective cross-sectional study of 139 medical radiation workers in six tertiary health-care institutions in northern Nigeria. Structured questionnaires were used to obtain vital information about the occurrence of occupational hazards, prevention and control measures. Data were analyzed using descriptive and inferential statistics using the computer software SPSS. Results: Out of 159 questionnaires distributed 139 were retrieved giving a response rate 87.4%. Stress, direct contact with bodily fluids, and contrast media splashes were the three most prevalent hazards reported by 121 (87.1%), 78 (56.1%), and 72 (51.8%), respectively. Conclusion: Medical radiation workers in Northern Nigeria face a wide range of occupational hazards, and therefore concerted efforts must be channeled toward mitigating these hazards.
目的:本研究的目的是确定尼日利亚北部医疗辐射工作者的职业危害流行率,并评估该地区现有职业安全措施的充分性。材料和方法:对尼日利亚北部六所三级医疗机构的139名医疗辐射工作者进行的前瞻性横断面研究。采用结构化调查问卷,获取职业病危害发生、防治措施等重要信息。数据分析采用描述性和推断统计学,并使用SPSS计算机软件。结果:在分发的159份问卷中,检索到139份,回复率为87.4%。压力、直接接触体液和造影剂飞溅是三种最常见的危害,分别有121份(87.1%)、78份(56.1%)和72份(51.8%)报告。结论:尼日利亚北部的医疗辐射工作者面临着广泛的职业危害,因此必须共同努力减轻这些危害。
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引用次数: 0
Role of computed tomography in identifying anatomical variations in chronic sinusitis: An observational study 计算机断层扫描在识别慢性鼻窦炎解剖变异中的作用:一项观察性研究
Pub Date : 2018-01-01 DOI: 10.4103/WAJR.WAJR_18_17
A. Reddy, Praful Kumar Kakumanu, C. Kondragunta, N. Gandra
Background/Aim: Clear visualization of bony wall, mucosal layer, sinus contents, and compartment by computed tomography (CT) helps to identify the anatomical variations in chronic sinusitis (CS). We describe the clinical and radiological features in CS. Materials and Methods: We included patients of both genders aged ≥15 years, with CS. Unenhanced CT images of the nasal cavity and paranasal region were taken in coronal, complemented by axial and sagittal reconstructions. Analysis of anatomical variants was performed using a soft tissue window and a bone window. Results: Headache (64%), nasal obstruction (53%), and nasal discharge (38%) were common complaints of 100 patients (male = 52) whose mean ± standard deviation age was 32.55 ± 10.9 years. Significant mucosal thickening in at least one of the paranasal sinuses (PNSs) was seen in all except four patients. All had a minimum of one anatomical variant, 72% had >1 variant. Maxillary antra were most commonly involved (62.0%), followed by ethmoid sinuses (36.0%). Deviated nasal septum (60%) was most common, followed by concha bullosa (38%); paradoxical middle turbinate (18%), ethmoidal bulla (20%), agger nasi cells (33%), Haller cells (21%), and onodi cells (10%) were other features. All had optic nerve involvement with Type I (84%) involvement being common. Kero's classification Type I was noted in 71%. None had Type IV. Cribriform plate and carotid canal wall were normal in all while 2% had dehiscence of lamina papyracea. Conclusion: CT plays an important role in visualization of anatomical variations in PNSs, and anatomical variations particularly in the ostiomeatal complex are the key factors in the causation of CS.
背景/目的:通过计算机断层扫描(CT)清晰地显示骨壁、粘膜层、鼻窦内容物和隔室,有助于识别慢性鼻窦炎(CS)的解剖学变异。我们描述了CS的临床和放射学特征。材料和方法:我们纳入年龄≥15岁的CS患者。鼻腔和副鼻区的非增强CT图像在冠状面拍摄,并辅以轴状和矢状面重建。使用软组织窗和骨窗进行解剖变异分析。结果:100例男性患者中,头痛(64%)、鼻塞(53%)、流鼻液(38%)是常见的主诉,平均±标准差年龄为32.55±10.9岁。除4例患者外,其余患者至少有1例鼻窦(PNSs)明显粘膜增厚。所有人都至少有一种解剖变异,72%的人有bbb1变异。上颌窦最常受累(62.0%),其次为筛窦(36.0%)。最常见的是鼻中隔偏曲(60%),其次是鼻甲大疱(38%);异中鼻甲(18%)、筛大泡(20%)、鼻窦炎细胞(33%)、Haller细胞(21%)和onodi细胞(10%)是其他特征。所有患者均有视神经受累,其中I型(84%)受累最为常见。Kero分类为I型的占71%。无IV型。筛状板和颈动脉管壁均正常,2%有纸莎草膜开裂。结论:CT对PNSs的解剖变异具有重要的可视化作用,尤其是口鼻道复合体的解剖变异是引起CS的关键因素。
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引用次数: 4
Herlyn-Werner-Wunderlich syndrome: A rare cause of pain in the left iliac fossa Herlyn-Werner-Wunderlich综合征:一种罕见的左髂窝疼痛原因
Pub Date : 2018-01-01 DOI: 10.4103/wajr.wajr_28_17
Antonio Ballester, M. Salvetti
Alterations of the Müllerian ducts are rare but often treatable causes of infertility. Uterus didelphys is caused by a complete or almost complete lack of fusion of the Müllerian ducts during embryological development. As a result, two separate symmetrical uterine cavities develop with two cervices and no communication between these cavities; this is often associated with a vaginal septum, which can have a transverse wall that blocks one of the hemivaginas. Symptoms begin to develop in menarche, and complications related to a retrograde menstrual flow arise, along with pelvic adhesions and endometriosis. Some kidney abnormalities may occur. Magnetic resonance imaging can be used to diagnose and distinguish surgically correctable forms of Müllerian duct alterations. The surgical approach depends on the imaging findings. The objective of this article is to describe the radiological characteristics of the Herlyn-Werner-Wunderlich syndrome.
胆囊管的改变是罕见的,但通常是可治疗的不孕原因。子宫双裂是由于胚胎发育过程中勒管完全或几乎完全缺乏融合引起的。结果,两个独立对称的子宫腔发育,有两个服务,这些腔之间没有通信;这通常与阴道间隔有关,它可以有一个横壁阻塞其中一个半阴道。症状在月经初潮时开始出现,并出现与月经倒流相关的并发症,以及盆腔粘连和子宫内膜异位症。可能会出现一些肾脏异常。磁共振成像可用于诊断和区分手术矫正形式的勒氏管改变。手术入路取决于影像学表现。本文的目的是描述herlin - werner - wunderlich综合征的放射学特征。
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引用次数: 0
A “three-eyed” infant: A case of partial facial duplication (diprosopus monocephalus triophthalmos) 一个“三眼”婴儿:部分面部重复病例(独头三眼双足蟾蜍)
Pub Date : 2018-01-01 DOI: 10.4103/WAJR.WAJR_33_17
Rabi Sani Yahaya, M. Suwaid, S. Hassan, Y. Lawal, I. Hassan, B. Gwaram, H. Yahaya
Craniofacial duplication known as diprosopus is a rare congenital disorder whereby parts or all of the face are duplicated on the head. This is a case of a 1-year-old boy referred to our hospital with an extra eye (third eye) on the left side of the head and an abnormally shaped head, which were noticed since birth. Pregnancy and delivery were uneventful. Apart from routine antenatal medication, there was no history suggestive of ingestion of traditional or other medication during pregnancy. No history of smoking during pregnancy and no history of exposure to radiation. The child was born in a rural area to a “nonconsanguineous marriage.” Examination revealed posterior plagiocephaly, a depressed anterior fontanelle, and a bulging posterior fontanelle. There was an extra eye (third eye) in the left temporal region. Radiologic findings showed the presence of two normally situated bony orbits and two extra orbits in the left temporal region. Well-formed globes were seen in the normal orbits while only one of the extra orbits contained a globe. The importance of prenatal diagnosis is emphasized.
颅面复制是一种罕见的先天性疾病,即面部的部分或全部复制在头部。这是一个1岁男孩的病例,他被转诊到我们医院,头部左侧多了一只眼睛(第三只眼睛),头部形状异常,这是从出生起就注意到的。怀孕和分娩都很顺利。除了常规的产前用药外,没有任何病史表明在妊娠期间摄入了传统药物或其他药物。妊娠期无吸烟史,无辐射暴露史。孩子出生在一个农村地区,“非血缘婚姻”。检查发现后斜头畸形、前囟门凹陷和后囟门凸起。左颞区多出一只眼睛(第三只眼睛)。放射学检查结果显示,左颞区有两个正常位置的骨性眼眶和两个额外的眼眶。在正常轨道上可以看到形状良好的地球仪,而只有一个额外的轨道包含地球仪。强调了产前诊断的重要性。
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引用次数: 1
Trend of cancer incidence in an oncology center in Nigeria 尼日利亚某肿瘤中心癌症发病率趋势分析
Pub Date : 2018-01-01 DOI: 10.4103/WAJR.WAJR_26_17
A. Sowunmi, A. Alabi, O. Fatiregun, T. Olatunji, U. Okoro, Abayomi Durosinmi Etti
Background: Globally, 32.5 million people diagnosed with cancer within the 5 years previously were alive at the end of 2012. 8.2 million deaths and 14.1 million new cases are recorded annually, but 70% will be in developing countries. Lung, breast, and colorectal cancers are commonly diagnosed. Aim and Objectives: The aim and objectives of this study is to review the trend of cancer incidence in Lagos University Teaching Hospital (LUTH) from January 2004 to December 2013.Materials and Methods: This is a retrospective study of histologically confirmed malignancies seen at Radiotherapy Department, LUTH from January 2004 to December 2013. Case files were retrieved through the record department, and the information required was extracted with the aid of a data extraction form. Results: A total of 3,314 new cases of cancer were recorded in LUTH during the study period. The mean age of cancer presentation is 48.52 (±16.44). The median age is 49.00 years with an age range of 1–100 years. The peak age incidence for males was 50–54 years accounting for 10% of all male presentation while females had a peak age incidence of 40–44 years accounting for 14% of female cases. The male-to-female ratio was 1:3. Breast (38.1%), cervical (17.0%), and colorectal cancers (3.3%) are the common ones recorded. In males, the most common cancer was prostate cancer (12.8%) followed by colorectal cancer (4.5%). Conclusion: In general, cancer incidence in Nigeria appears low compared to developed countries which may not truly reflect the burden of the disease. This could be due to poor population-based statistics and poor health patronage of orthodox medical care.
背景:截至2012年底,全球5年内确诊的癌症患者中有3250万人存活。每年有820万人死亡,1410万新病例,但70%将发生在发展中国家。肺癌、乳腺癌和结直肠癌是常见病。目的和目的:本研究的目的和目的是回顾2004年1月至2013年12月拉各斯大学教学医院(LUTH)癌症发病率的趋势。材料与方法:回顾性研究2004年1月至2013年12月在LUTH放射科病理证实的恶性肿瘤。通过记录部门检索案件档案,并借助数据提取表格提取所需的信息。结果:在研究期间,LUTH共记录了3314例新发癌症病例。癌症出现的平均年龄为48.52岁(±16.44岁)。年龄中位数为49.00岁,年龄范围为1-100岁。男性发病高峰年龄为50-54岁,占所有男性病例的10%;女性发病高峰年龄为40-44岁,占女性病例的14%。男女比例为1:3。乳腺癌(38.1%)、宫颈癌(17.0%)和结直肠癌(3.3%)是常见的癌症。在男性中,最常见的癌症是前列腺癌(12.8%),其次是结肠直肠癌(4.5%)。结论:总的来说,与发达国家相比,尼日利亚的癌症发病率似乎较低,这可能无法真正反映该疾病的负担。这可能是由于基于人口的统计数据不准确,以及传统医疗保健的卫生赞助不足。
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引用次数: 17
3-Tesla magnetic resonance imaging evaluation of intraspinal extramedullary nonosseous neoplastic lesions with their postsurgical and histopathological correlation 3特斯拉磁共振成像评价椎管内髓外非骨肿瘤病变及其术后和组织病理学相关性
Pub Date : 2018-01-01 DOI: 10.4103/wajr.wajr_25_17
Neeraj Prajapati, S. K. Rastogi, Y. Kumar, Abhinav Pandit, Nisma Wahed, Navreet Singh
Aims: This study aimed to evaluate the diagnostic ability of 3-Tesla magnetic resonance imaging (MRI) in detection and characterization of intraspinal extramedullary nonosseous neoplastic lesions and their histopathological correlation. Settings and Design: It was a prospective study involving fifty patients who presented with low backache and lower limb weakness with MRI findings suggestive of a neoplastic extramedullary intraspinal lesion. Patients and Methods: A 3-Tesla 16-channel MRI scanner was used for imaging. Multiplanar imaging was done using T1, T2, short-tau inversion recovery sequences and T1 fat-saturated sequences. All patients then underwent postgadolinium MRI. The findings of MRI were then reviewed. An analysis of correlation between MRI findings and surgical and histopathological findings was done. Results: Out of the fifty patients evaluated, intradural lesions were noted in forty patients and extradural lesions in ten patients. Schwannoma was the most common tumor, followed by meningioma in the intradural category. Two rare cases of intradural lipoma and malignant peripheral nerve sheath tumors were also detected. In extradural category, metastasis was the most common lesion along with two rare lesions of epidural meningioma and leukemia-associated granulocytic sarcoma. Conclusions: MRI is an indispensable tool in the evaluation of spinal neoplasms. Its multiplanar capability, high-quality soft-tissue resolution, and depiction of various anatomic landmarks help the neurosurgeon to make a road map for the surgery. In most of the cases, MRI can give information regarding the histopathology of the lesion. However, in some cases, differential diagnosis needs to be included, especially in cases of extradural meningiomas and malignant peripheral nerve sheath tumors, because of their rare incidence.
目的:本研究旨在评估3特斯拉磁共振成像(MRI)在检测和表征椎管内髓外非骨肿瘤病变及其组织病理学相关性方面的诊断能力。设置和设计:这是一项前瞻性研究,涉及50名出现腰痛和下肢无力的患者,MRI结果提示髓外椎管内肿瘤病变。患者和方法:使用3特斯拉16通道MRI扫描仪进行成像。使用T1、T2、短τ反转恢复序列和T1脂肪饱和序列进行多平面成像。所有患者随后接受钆后MRI检查。然后对MRI的检查结果进行回顾。对MRI检查结果与手术和组织病理学检查结果之间的相关性进行了分析。结果:在评估的50名患者中,40名患者出现硬膜内病变,10名患者出现硬脑膜外病变。神经鞘瘤是最常见的肿瘤,其次是硬膜内脑膜瘤。还发现了两例罕见的硬膜内脂肪瘤和恶性周围神经鞘肿瘤。在硬膜外类中,转移是最常见的病变,硬膜外脑膜瘤和白血病相关粒细胞肉瘤是两种罕见的病变。结论:MRI是评价脊柱肿瘤不可或缺的工具。它的多平面能力、高质量的软组织分辨率和对各种解剖标志的描绘有助于神经外科医生制定手术路线图。在大多数情况下,MRI可以提供有关病变组织病理学的信息。然而,在某些情况下,需要包括鉴别诊断,特别是在硬膜外脑膜瘤和恶性周围神经鞘肿瘤的情况下,因为它们的发病率很低。
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West African Journal of Radiology
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