Pub Date : 2024-01-02DOI: 10.56501/intjorthodrehabil.v14i4.877
Sandra Sagar, P. Ramani, M. Yuwanati, Sagar Moses, Karthikeyan Ramalingam
BACKGROUND: 1,25 dihydroxycholecalciferol, the active form of vitamin D3 is known to play an important role in mineralization. Vitamin D3 is also known to have immune-supporting properties by regulating various cytokines and cell signalling pathways. AIM: To review the role of 1,25-dihydroxycholecalciferol (Vitamin D3) on the rate of Orthodontic tooth movement. METHODS: This study applied a systematic review to analyse the current literature to define and summarise the role of I,25-dihydroxycholecalciferol on the rate of Orthodontic tooth movement. A comprehensive search was done using electronic databases such as PubMed Central, Cochrane Database of Systematic Reviews, Google Scholar, EMBASE and direct web search. The title scan was done to identify relevant articles which are further evaluated for inclusion by reading the abstract. RESULTS: The electronic database search identified 28 articles. 3 articles were selected based on the selection criteria to meet the research question. There was about 60% faster rate of orthodontic tooth movement when a dosage of 40-50 pg/dl of 1,25 dihydroxycholecalciferol was supplemented. Administration of 1,25-dihydroxycholecalciferol showed no deleterious effects to the tooth roots or the surrounding tissues as evidenced from the periapical radiographs and CBCT. CONCLUSION: Based on the collected data, the local administration of an active form of Vitamin D3, 1,25-dihydroxycholecalciferol can act as an effective supplement to accelerate Orthodontic Tooth Movement (OTM).
{"title":"Role of 1,25 Dihydroxycholecalciferol on the Rate of Orthodontic Tooth Movement- A Systematic Review","authors":"Sandra Sagar, P. Ramani, M. Yuwanati, Sagar Moses, Karthikeyan Ramalingam","doi":"10.56501/intjorthodrehabil.v14i4.877","DOIUrl":"https://doi.org/10.56501/intjorthodrehabil.v14i4.877","url":null,"abstract":"BACKGROUND: 1,25 dihydroxycholecalciferol, the active form of vitamin D3 is known to play an important role in mineralization. Vitamin D3 is also known to have immune-supporting properties by regulating various cytokines and cell signalling pathways.\u0000AIM: To review the role of 1,25-dihydroxycholecalciferol (Vitamin D3) on the rate of Orthodontic tooth movement.\u0000METHODS: This study applied a systematic review to analyse the current literature to define and summarise the role of I,25-dihydroxycholecalciferol on the rate of Orthodontic tooth movement. A comprehensive search was done using electronic databases such as PubMed Central, Cochrane Database of Systematic Reviews, Google Scholar, EMBASE and direct web search. The title scan was done to identify relevant articles which are further evaluated for inclusion by reading the abstract.\u0000RESULTS: The electronic database search identified 28 articles. 3 articles were selected based on the selection criteria to meet the research question. There was about 60% faster rate of orthodontic tooth movement when a dosage of 40-50 pg/dl of 1,25 dihydroxycholecalciferol was supplemented. Administration of 1,25-dihydroxycholecalciferol showed no deleterious effects to the tooth roots or the surrounding tissues as evidenced from the periapical radiographs and CBCT. \u0000CONCLUSION: Based on the collected data, the local administration of an active form of Vitamin D3, 1,25-dihydroxycholecalciferol can act as an effective supplement to accelerate Orthodontic Tooth Movement (OTM).","PeriodicalId":29888,"journal":{"name":"International Journal of Orthodontic Rehabilitation","volume":"68 16","pages":""},"PeriodicalIF":0.3,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139390024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-02DOI: 10.56501/intjorthodrehabil.v14i4.910
S. Faizee, Pavithra M, Palivela Manvitha, Hemamalini D
OBJECTIVE: To evaluate the antimicrobial effects of orthodontic band cement incorporated with various biosynthesized nanoparticles. MATERIALS AND METHODS: Zirconia, gold, copper Nanoparticles were green synthesized using white tea extract and dry ginger which are incorporated into orthodontic band cement, characterized using FTIR analysis. Antimicrobial activity against Streptococcus mutans and Lactobacillus acidophilus was tested in vitro by disc diffusion and Time Kill Curve Assay. RESULTS: Zirconia nanoparticles incorporated GIC exhibited better antimicrobial activity against streptococcus mutans, and gold nanoparticles incorporated GIC against lactobacillus acidophilus at varying concentrations at different time period. CONCLUSION: The antibacterial effect against streptococcus mutans and lactobacillus acidophilus were distinctly noted in Zirconia nanoparticles, gold nanoparticles followed by copper nanoparticles. Zirconia and gold nanoparticles produced more efficient antibacterial property and eventually would be effective in curtailing White Spot Lesions.
{"title":"Evaluation Of Antimicrobial Effects Of Orthodontic Band Cement Incorporated With Zirconia, Gold, Copper Biosynthesized Nanoparticles- An In-Vitro Study","authors":"S. Faizee, Pavithra M, Palivela Manvitha, Hemamalini D","doi":"10.56501/intjorthodrehabil.v14i4.910","DOIUrl":"https://doi.org/10.56501/intjorthodrehabil.v14i4.910","url":null,"abstract":"OBJECTIVE: To evaluate the antimicrobial effects of orthodontic band cement incorporated with various biosynthesized nanoparticles.\u0000MATERIALS AND METHODS: Zirconia, gold, copper Nanoparticles were green synthesized using white tea extract and dry ginger which are incorporated into orthodontic band cement, characterized using FTIR analysis. Antimicrobial activity against Streptococcus mutans and Lactobacillus acidophilus was tested in vitro by disc diffusion and Time Kill Curve Assay.\u0000RESULTS: Zirconia nanoparticles incorporated GIC exhibited better antimicrobial activity against streptococcus mutans, and gold nanoparticles incorporated GIC against lactobacillus acidophilus at varying concentrations at different time period.\u0000CONCLUSION: The antibacterial effect against streptococcus mutans and lactobacillus acidophilus were distinctly noted in Zirconia nanoparticles, gold nanoparticles followed by copper nanoparticles. Zirconia and gold nanoparticles produced more efficient antibacterial property and eventually would be effective in curtailing White Spot Lesions.\u0000 ","PeriodicalId":29888,"journal":{"name":"International Journal of Orthodontic Rehabilitation","volume":"111 36","pages":""},"PeriodicalIF":0.3,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139391582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background:
Epigenetic regulators play a vital role in determining a complex phenotype. The Skeletal Class II malocclusion is one such phenotype, which is a polygenic, complex disorder. The identification of epigenetic regulators would aid in understanding the complex relationship between the epigenetic marks and the phenotype. Also, these epigenetic marks can be considered for developing diagnostic leads upon validation for a specific disorder.
Materials and methods:
The present study follows an observational study design, which was performed using computational tools. The preliminary data about the genes associated with the Skeletal class II malocclusion was derived from DisGeNet, followed by identification of the protein-protein interaction networks. The microRNA targets were then identified using miRDB and the unique microRNA population common to all the five genes were further curated using the Venn plot.
Results:
The DisGeNet database provided information on the genes that were associated with skeletal Class II malocclusion. The five genes identified were ACTN3, GH1, HDAC4, HMGA2 and KAT6B. One microRNA, hsa-miR-892c-5p was unique to ACTN3, HDAC4 and HMGA2. The hsa-miR-3925-5p and hsa-miR-590-3p were found to be common to the genes ACTN3, HDAC4 and GH1 + HMGA2 respectively.
Discussion:
The identification of microRNAs targeting candidate genes could aid in defining the role of these microRNAs in establishing the phenotype. The future scope of this study lies in curating microRNAs that are common to class II malocclusion related candidate genes. This panel of differentially expressed microRNAs can further be developed as early diagnostic marker, for identifying the skeletal abnormality that they would be possibly associated with.
{"title":"MicroRNA regulators of candidate genes involved in Class II skeletal malocclusion - A data mining approach.","authors":"Ashwin Mathew George, None Anitha P, Sumathi Felicita A, None Vijayashree Priyadharsini J, None Prasanna Arvind T.R","doi":"10.56501/intjorthodrehabil.v14i3.904","DOIUrl":"https://doi.org/10.56501/intjorthodrehabil.v14i3.904","url":null,"abstract":"Background: 
 Epigenetic regulators play a vital role in determining a complex phenotype. The Skeletal Class II malocclusion is one such phenotype, which is a polygenic, complex disorder. The identification of epigenetic regulators would aid in understanding the complex relationship between the epigenetic marks and the phenotype. Also, these epigenetic marks can be considered for developing diagnostic leads upon validation for a specific disorder.
 Materials and methods:
 The present study follows an observational study design, which was performed using computational tools. The preliminary data about the genes associated with the Skeletal class II malocclusion was derived from DisGeNet, followed by identification of the protein-protein interaction networks. The microRNA targets were then identified using miRDB and the unique microRNA population common to all the five genes were further curated using the Venn plot.
 Results:
 The DisGeNet database provided information on the genes that were associated with skeletal Class II malocclusion. The five genes identified were ACTN3, GH1, HDAC4, HMGA2 and KAT6B. One microRNA, hsa-miR-892c-5p was unique to ACTN3, HDAC4 and HMGA2. The hsa-miR-3925-5p and hsa-miR-590-3p were found to be common to the genes ACTN3, HDAC4 and GH1 + HMGA2 respectively.
 Discussion:
 The identification of microRNAs targeting candidate genes could aid in defining the role of these microRNAs in establishing the phenotype. The future scope of this study lies in curating microRNAs that are common to class II malocclusion related candidate genes. This panel of differentially expressed microRNAs can further be developed as early diagnostic marker, for identifying the skeletal abnormality that they would be possibly associated with.
","PeriodicalId":29888,"journal":{"name":"International Journal of Orthodontic Rehabilitation","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136182224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-07DOI: 10.56501/intjorthodrehabil.v14i3.882
Savani Sawant, Nitin Gulve, Amit Nehete, Shivpirya Aher
Introduction: Successful orthodontic treatment depends on the adhesive used for bonding orthodontic brackets and patient cooperation. Resin based adhesives are conventionally used but have drawbacks like white spot lesions and technique sensitivity. To overcome these problems, Resin modified glass ionomer cements (RMGIC) were introduced to utilise the fluoride releasing characteristic of GIC. Aim: To compare and evaluate bond failure rate and type of bond failure between brackets bonded with RMGIC and composite. Materials and methods: 25 patients undergoing orthodontic treatment were included and evaluated for 6 months. Bonding was done with RMGIC and composite. Patients were recalled every month and bond failure rate and type of bond failure was evaluated. Results: A total of 526 teeth were bonded out of which 263 were bonded with RMGIC and 263 with composite. Statistical analysis was done with Chi-square test (p>0.05). Maximum debonding was seen in RMGIC group (6.46%) compared to composite (3.42%). Maximum debonding was seen in 1st molars bonded with RMGIC (35.3%). Majority bond failure type observed was Adhesive enamel failure in brackets bonded with RMGIC. Conclusion: From the study, it can be concluded that bond failure was commonly seen in RMGIC group in comparison with composite group. Adhesive enamel failure was the most commonly seen bracket failure type. RMGIC had majority bracket failure but within acceptable range and hence can be used as a substitute adhesive for bonding.
{"title":"Comparative Evaluation Of Bond Failure Rate Of Orthodontic Brackets Bonded With Resin Modified Glass Ionomer Cement And Composite- A Randomized Control Trial","authors":"Savani Sawant, Nitin Gulve, Amit Nehete, Shivpirya Aher","doi":"10.56501/intjorthodrehabil.v14i3.882","DOIUrl":"https://doi.org/10.56501/intjorthodrehabil.v14i3.882","url":null,"abstract":"Introduction: Successful orthodontic treatment depends on the adhesive used for bonding orthodontic brackets and patient cooperation. Resin based adhesives are conventionally used but have drawbacks like white spot lesions and technique sensitivity. To overcome these problems, Resin modified glass ionomer cements (RMGIC) were introduced to utilise the fluoride releasing characteristic of GIC. Aim: To compare and evaluate bond failure rate and type of bond failure between brackets bonded with RMGIC and composite. Materials and methods: 25 patients undergoing orthodontic treatment were included and evaluated for 6 months. Bonding was done with RMGIC and composite. Patients were recalled every month and bond failure rate and type of bond failure was evaluated. Results: A total of 526 teeth were bonded out of which 263 were bonded with RMGIC and 263 with composite. Statistical analysis was done with Chi-square test (p>0.05). Maximum debonding was seen in RMGIC group (6.46%) compared to composite (3.42%). Maximum debonding was seen in 1st molars bonded with RMGIC (35.3%). Majority bond failure type observed was Adhesive enamel failure in brackets bonded with RMGIC. Conclusion: From the study, it can be concluded that bond failure was commonly seen in RMGIC group in comparison with composite group. Adhesive enamel failure was the most commonly seen bracket failure type. RMGIC had majority bracket failure but within acceptable range and hence can be used as a substitute adhesive for bonding.","PeriodicalId":29888,"journal":{"name":"International Journal of Orthodontic Rehabilitation","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135302378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-26DOI: 10.56501/intjorthodrehabil.v14i3.806
Namita Nadukuru, Padmapriya C V, Praveen Kumar Varma D, Anoosha Manda, Pradeep K, None V Sai Keerthi
INTRODUCTION: Malocclusion and TMD were believed to have a correlation when it is associated that the alteration of form might cause alteration in the stomatognathic system function. A multidisciplinary approach is particularly important for the successful treatment of chronic TMD cases. Management of TMD involves the work of dentists from various specialities. It is multifactorial in nature and requires proper examination and treatment planning. Thus, the primary purpose of this study is to find out the awareness of TMDs among postgraduate students. MATERIALS AND METHODOLOGY: The present study was retrospective in nature. A questionnaire involving TMDs was sent to all postgraduates involved in patient treatment through google forms. All participants were asked to anonymously answer the structured questionnaire containing multiple-choice and open-text questions in google forms. The questionnaire was specially developed for students and was organized into three sections. RESULTS: 204 participants responded and returned the completed questionnaires. Results showed that 98 % of the respondent’s occlusal disturbance causes TMD and TMJ problems are associated with malocclusion. The majority of the participants were aware of the aetiology and diagnosis but only 53% of them were aware of the treatment protocols. CONCLUSION: The causes and diagnosis domains of the questionnaire yielded a high degree of agreement while the treatment modalities were not known. Most of them were not aware of the treatment modalities reason being a lack of knowledge during the course of their undergraduate and postgraduate study.
{"title":"Knowledge and Awareness of Temporomandibular Disorders (TMDs) among Post-graduate residents","authors":"Namita Nadukuru, Padmapriya C V, Praveen Kumar Varma D, Anoosha Manda, Pradeep K, None V Sai Keerthi","doi":"10.56501/intjorthodrehabil.v14i3.806","DOIUrl":"https://doi.org/10.56501/intjorthodrehabil.v14i3.806","url":null,"abstract":"INTRODUCTION: Malocclusion and TMD were believed to have a correlation when it is associated that the alteration of form might cause alteration in the stomatognathic system function. A multidisciplinary approach is particularly important for the successful treatment of chronic TMD cases. Management of TMD involves the work of dentists from various specialities. It is multifactorial in nature and requires proper examination and treatment planning. Thus, the primary purpose of this study is to find out the awareness of TMDs among postgraduate students. MATERIALS AND METHODOLOGY: The present study was retrospective in nature. A questionnaire involving TMDs was sent to all postgraduates involved in patient treatment through google forms. All participants were asked to anonymously answer the structured questionnaire containing multiple-choice and open-text questions in google forms. The questionnaire was specially developed for students and was organized into three sections. RESULTS: 204 participants responded and returned the completed questionnaires. Results showed that 98 % of the respondent’s occlusal disturbance causes TMD and TMJ problems are associated with malocclusion. The majority of the participants were aware of the aetiology and diagnosis but only 53% of them were aware of the treatment protocols. CONCLUSION: The causes and diagnosis domains of the questionnaire yielded a high degree of agreement while the treatment modalities were not known. Most of them were not aware of the treatment modalities reason being a lack of knowledge during the course of their undergraduate and postgraduate study.","PeriodicalId":29888,"journal":{"name":"International Journal of Orthodontic Rehabilitation","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135720670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-17DOI: 10.56501/intjorthodrehabil.v14i3.763
R. Jain, M. Maliael, S. Pitchaipillai
Aim The aim of this investigation was to evaluate the antimicrobial activity and anti-biofilm activity of Cucurbita Maxima leaf extract on Streptococcus mutans isolated from dental plaque of subjects undergoing orthodontic treatment. Methodology Dental plaque samples were collected from out patients undergoing orthodontic treatment. From the plaque samples Biochemical Characterisation of Streptococcus mutans then Collection of Medicinal Plants was done followed by Preparation of Solvent Extract and stock Solution. Evaluation of Minimum Inhibitory Concentration (MIC) of the plant extract and Biofilm Inhibition Assay with Gas Chromatography-Mass Spectrum Analysis (GCMS) was carried out. Results The MIC was identified to be 1.25mg/ml. The biofilm inhibition assay showed that the extract did not inhibit the formation of the biofilm. The GCMS analysis identified twenty five constituent compounds from the crude extract. Conclusion The C. maxima leaf extract showed antibacterial activity against S. mutans and the minimum inhibitory concentration was identified at 1.25mg/ml. The extract did not inhibit the formation of biofilm.
{"title":"Evaluation of Antibacterial and Antibiofilm Activity of Cucurbita Maxima Leaf Extract Against Streptococcus Mutans Isolated from Orthodontic Patients","authors":"R. Jain, M. Maliael, S. Pitchaipillai","doi":"10.56501/intjorthodrehabil.v14i3.763","DOIUrl":"https://doi.org/10.56501/intjorthodrehabil.v14i3.763","url":null,"abstract":"Aim\u0000The aim of this investigation was to evaluate the antimicrobial activity and anti-biofilm activity of Cucurbita Maxima leaf extract on Streptococcus mutans isolated from dental plaque of subjects undergoing orthodontic treatment.\u0000Methodology\u0000Dental plaque samples were collected from out patients undergoing orthodontic treatment. From the plaque samples Biochemical Characterisation of Streptococcus mutans then Collection of Medicinal Plants was done followed by Preparation of Solvent Extract and stock Solution. Evaluation of Minimum Inhibitory Concentration (MIC) of the plant extract and Biofilm Inhibition Assay with Gas Chromatography-Mass Spectrum Analysis (GCMS) was carried out.\u0000Results\u0000The MIC was identified to be 1.25mg/ml. The biofilm inhibition assay showed that the extract did not inhibit the formation of the biofilm. The GCMS analysis identified twenty five constituent compounds from the crude extract. \u0000Conclusion \u0000The C. maxima leaf extract showed antibacterial activity against S. mutans and the minimum inhibitory concentration was identified at 1.25mg/ml. The extract did not inhibit the formation of biofilm. ","PeriodicalId":29888,"journal":{"name":"International Journal of Orthodontic Rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48615406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-28DOI: 10.56501/intjorthodrehabil.v14i3.826
Sanjana Thiagarajan, U. Gopalakrishnan, Koduri Manoghna, B. R.
Objectives : To assess the effects of melatonin and its agonist on bone tissue through a scoping review of the literature. Materials and Methods: The keywords were searched on Scopus, Web of Science, and PubMed. Title and abstracts were reviewed to exclude the duplicates and irrelevant articles. The full-text articles were then screened in accordance with the inclusion criteria. Results: Of the 5,383 identified articles [PubMed=5,508, Web of Science=122, Scopus=53], only 3 studies qualified to be included in the scoping review based on the inclusion criteria. The first study assessed effects of the oral melatonin on bone integrity and mass in postmenopausal osteopenic women through dual X-ray absorptiometry, quantitative computed tomography (QCT), high-resolution peripheral QCT (HR-pQCT), determined calciotropic hormones and bone markers. The other two studies evaluated radiographic and clinical outcomes such as Perio test, Angulated Bleeding test, Pink Esthetic Score (PES), Gingival index (GI), Peri-implant sulcus depth (PD), Wound healing index (WHI), Linear measurements of bone loss around implant and Densitometric analysis of dental implants with the local application of melatonin. All studies showed an improved outcome parameters in comparison with the control group. Conclusion: Based on the findings of the included studies, it was found that melatonin improved bone mineral density, increased marginal bone level and minimized root resorption aiding in implant stability. The findings were suggestive that melatonin has osteoinductive properties and inhibitory effect on osteoclastic activity.
目的：通过文献综述来评估褪黑素及其激动剂对骨组织的影响。材料和方法：在Scopus、Web of Science和PubMed上搜索关键词。对标题和摘要进行了审查，以排除重复和不相关的文章。然后根据纳入标准对全文文章进行筛选。结果：在5383篇已确定的文章[PubMed=5508，Web Of Science=122，Scopus=53]中，根据纳入标准，只有3项研究符合纳入范围审查的条件。第一项研究通过双X射线吸收仪、定量计算机断层扫描（QCT）、高分辨率外周QCT（HR-pQCT）和促钙激素和骨标志物测定，评估了口服褪黑素对绝经后骨质疏松妇女骨完整性和骨质量的影响。另外两项研究评估了放射学和临床结果，如Perio测试、Angularized Bleeding测试、Pink Esthetic Score（PES）、牙龈指数（GI）、种植体周围沟深度（PD）、伤口愈合指数（WHI）、种植物周围骨损失的线性测量以及局部应用褪黑素的牙科种植体密度分析。所有研究显示，与对照组相比，结果参数有所改善。结论：根据纳入的研究结果，发现褪黑素可以改善骨密度，提高边缘骨水平，最大限度地减少牙根吸收，有助于种植体的稳定性。研究结果提示褪黑素具有骨诱导特性和对破骨细胞活性的抑制作用。
{"title":"The Effect of Melatonin and Its Agonist on Bone Metabolism","authors":"Sanjana Thiagarajan, U. Gopalakrishnan, Koduri Manoghna, B. R.","doi":"10.56501/intjorthodrehabil.v14i3.826","DOIUrl":"https://doi.org/10.56501/intjorthodrehabil.v14i3.826","url":null,"abstract":"\u0000Objectives : To assess the effects of melatonin and its agonist on bone tissue through a scoping review of the literature. \u0000Materials and Methods: The keywords were searched on Scopus, Web of Science, and PubMed. Title and abstracts were reviewed to exclude the duplicates and irrelevant articles. The full-text articles were then screened in accordance with the inclusion criteria. \u0000Results: Of the 5,383 identified articles [PubMed=5,508, Web of Science=122, Scopus=53], only 3 studies qualified to be included in the scoping review based on the inclusion criteria. The first study assessed effects of the oral melatonin on bone integrity and mass in postmenopausal osteopenic women through dual X-ray absorptiometry, quantitative computed tomography (QCT), high-resolution peripheral QCT (HR-pQCT), determined calciotropic hormones and bone markers. The other two studies evaluated radiographic and clinical outcomes such as Perio test, Angulated Bleeding test, Pink Esthetic Score (PES), Gingival index (GI), Peri-implant sulcus depth (PD), Wound healing index (WHI), Linear measurements of bone loss around implant and Densitometric analysis of dental implants with the local application of melatonin. All studies showed an improved outcome parameters in comparison with the control group. \u0000Conclusion: Based on the findings of the included studies, it was found that melatonin improved bone mineral density, increased marginal bone level and minimized root resorption aiding in implant stability. The findings were suggestive that melatonin has osteoinductive properties and inhibitory effect on osteoclastic activity.\u0000","PeriodicalId":29888,"journal":{"name":"International Journal of Orthodontic Rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45503287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.56501/intjorthodrehabil.v14i2.870
Arshya Kumar, Srirengalakshmi Muthuswamy Pandian
Introduction: The most hidden and inaccessible of all the paranasal air sinuses is the sphenoid sinus, a cavity with an irregular shape that is situated in the middle of the cranial base. Since the anterior cranial base shows little growth after the age of 7, it is regarded as a stable reference for cephalometric analysis. Objective: The aim of this study was to predict skeletal malocclusion by correlating the length of the cranial base and the volume of the sphenoid sinus in different sagittal skeletal patterns.Materials and methodology: In this study, a total of 30 cone beam computed tomography (CBCT) scans of patients, aged between 18 and 35 years who underwent orthodontic and orthognathic treatment were evaluated. DICOM files from the CBCT scans were imported and viewed using Dolphin imaging software. Skeletal malocclusion was evaluated using a lateral cephalogram obtained from the CBCT. Volumetric analysis of the sphenoid sinus and length of the cranial base was evaluated with the help of the Dolphin imaging software. A normality test was done to decide the statistical method for data analysis. A one-way ANOVA with Tukey’s post hoc test was done to compare the three groups. Results: There was a correlation noted between the volume of the sphenoid sinus in skeletal class II malocclusion but no correlation was noted in the length of the cranial base. The mean value of the volume of the sphenoid sinus in subjects with class II skeletal malocclusion was 12613.50± 2023.409 which was greater compared to the other skeletal malocclusions.Conclusion: Sphenoid sinus volume was reported to be increased in subjects with skeletal class II malocclusion but there was no correlation between the cranial base length and sphenoid sinus volume in any group.
{"title":"Evaluation Of Sphenoid Sinus Volume And Cranial Base Length In Subjects With Different Sagittal Skeletal Malocclusions","authors":"Arshya Kumar, Srirengalakshmi Muthuswamy Pandian","doi":"10.56501/intjorthodrehabil.v14i2.870","DOIUrl":"https://doi.org/10.56501/intjorthodrehabil.v14i2.870","url":null,"abstract":"Introduction: The most hidden and inaccessible of all the paranasal air sinuses is the sphenoid sinus, a cavity with an irregular shape that is situated in the middle of the cranial base. Since the anterior cranial base shows little growth after the age of 7, it is regarded as a stable reference for cephalometric analysis. Objective: The aim of this study was to predict skeletal malocclusion by correlating the length of the cranial base and the volume of the sphenoid sinus in different sagittal skeletal patterns.Materials and methodology: In this study, a total of 30 cone beam computed tomography (CBCT) scans of patients, aged between 18 and 35 years who underwent orthodontic and orthognathic treatment were evaluated. DICOM files from the CBCT scans were imported and viewed using Dolphin imaging software. Skeletal malocclusion was evaluated using a lateral cephalogram obtained from the CBCT. Volumetric analysis of the sphenoid sinus and length of the cranial base was evaluated with the help of the Dolphin imaging software. A normality test was done to decide the statistical method for data analysis. A one-way ANOVA with Tukey’s post hoc test was done to compare the three groups. Results: There was a correlation noted between the volume of the sphenoid sinus in skeletal class II malocclusion but no correlation was noted in the length of the cranial base. The mean value of the volume of the sphenoid sinus in subjects with class II skeletal malocclusion was 12613.50± 2023.409 which was greater compared to the other skeletal malocclusions.Conclusion: Sphenoid sinus volume was reported to be increased in subjects with skeletal class II malocclusion but there was no correlation between the cranial base length and sphenoid sinus volume in any group.\u0000 ","PeriodicalId":29888,"journal":{"name":"International Journal of Orthodontic Rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49335730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.56501/intjorthodrehabil.v14i2.879
Havisha Nookala, Nivethigaa Balakrishnan
Background- Arch expansion is one of the non- extraction methods of gaining space. This study aims to assess and compare the arch expansion achieved during initial leveling and alignment with three different bracket-archwire combinations. Material and Methods- This was a retrospective study done in a university setup. From the available patient information archives, records of 30 subjects based on their advocated bracket system were identified and categorized into three groups. Their pre-treatment (T0) and post aligning (T2) 3D model maxillary scans were superimposed according to the reference points marked on the third palatal rugae using an OrthoAnalyzer software(3 shape version 19.0) to assess the changes in Intercanine width (ICW), Inter-premolar width (IPW) and Intermolar width (IMW) and arch length. For the recorded data, descriptive statistics, One-way ANOVA and Tukey HSD post hoc were analyzed using SPSS software. Results- Except for the Damon group that showed considerable increase in the intermolar and premolar dimensions, other groups had no statistically significant differences in terms of Intercanine width, Interpremolar width, and Intermolar width and Arch length. Conclusion- Changes in the transverse dimension were noticed among all the three groups with maximum in the Damon bracket and Damon archwire combination. Although the difference in expansion between groups showed no statistically significant difference, it was appreciated clinically in relieving dental crowding.
背景拱扩展是一种获取空间的非提取方法。本研究旨在评估和比较三种不同支架-弓丝组合在初始调平和对准过程中获得的弓扩张。材料和方法:这是一项在大学进行的回顾性研究。从现有的患者信息档案中，根据30例患者的主张支架系统，将其分为三组。使用OrthoAnalyzer软件(3 shape version 19.0)，根据第三腭纹上标记的参考点，将治疗前(T0)和对齐后(T2) 3D上颌模型扫描叠加，评估齿间宽度(ICW)、前磨牙宽度(IPW)、磨牙宽度(IMW)和弓长的变化。对记录的资料采用SPSS软件进行描述性统计、单因素方差分析和Tukey HSD事后分析。结果-除了Damon组在磨牙间和前磨牙尺寸上有明显的增加外，其他组在犬齿间宽度、后磨牙宽度、磨牙间宽度和牙弓长度上没有统计学上的显著差异。结论:三组患者的横向尺寸均有明显变化，其中以Damon托槽和Damon弓丝组合的变化最大。虽然两组间牙体扩张的差异无统计学意义，但在缓解牙体拥挤方面具有临床应用价值。
{"title":"Evaluation of Maxillary Transverse Arch Dimensions Following Leveling and Alignment with Different Archwire-Bracket Combinations During Fixed Appliance Treatment - A Retrospective Study","authors":"Havisha Nookala, Nivethigaa Balakrishnan","doi":"10.56501/intjorthodrehabil.v14i2.879","DOIUrl":"https://doi.org/10.56501/intjorthodrehabil.v14i2.879","url":null,"abstract":"Background- Arch expansion is one of the non- extraction methods of gaining space. This study aims to assess and compare the arch expansion achieved during initial leveling and alignment with three different bracket-archwire combinations. \u0000Material and Methods- This was a retrospective study done in a university setup. From the available patient information archives, records of 30 subjects based on their advocated bracket system were identified and categorized into three groups. Their pre-treatment (T0) and post aligning (T2) 3D model maxillary scans were superimposed according to the reference points marked on the third palatal rugae using an OrthoAnalyzer software(3 shape version 19.0) to assess the changes in Intercanine width (ICW), Inter-premolar width (IPW) and Intermolar width (IMW) and arch length. For the recorded data, descriptive statistics, One-way ANOVA and Tukey HSD post hoc were analyzed using SPSS software. \u0000Results- Except for the Damon group that showed considerable increase in the intermolar and premolar dimensions, other groups had no statistically significant differences in terms of Intercanine width, Interpremolar width, and Intermolar width and Arch length. \u0000Conclusion- Changes in the transverse dimension were noticed among all the three groups with maximum in the Damon bracket and Damon archwire combination. Although the difference in expansion between groups showed no statistically significant difference, it was appreciated clinically in relieving dental crowding. ","PeriodicalId":29888,"journal":{"name":"International Journal of Orthodontic Rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43125082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
INTRODUCTION: Bonding of buccal tubes to the tooth is an essential procedure in orthodontic treatment. With the increase in the number of adult patients seeking fixed orthodontic treatment, there is a need to find a more reliable procedure to bond the artificial crown surface. Successful orthodontic treatment requires sufficiently high and durable bond between buccal tubes and ceramic/zirconia surfaces. There is a need for a bonding agent which can provide maximum bond strength to all surfaces. This study aimed to assess and compare the shear bond strength and adhesive remnants of orthodontic buccal tubes to natural teeth, ceramic crowns and zirconia crowns using two different bonding systems. METHODS: In this in vitro study, 60 extracted human molar teeth were randomly assigned to three groups (n=20) and then divided into two subgroups(n=10). Bonding of buccal tubes to enamel, ceramic and zirconia surfaces was done using Assure plus universal bonding resin and Enhance LC. The shear bond strength of buccal tubes to the enamel, ceramic and zirconia surfaces were determined by universal testing machine. The SBSs and ARI scores were statistically analysed with and Kruskal Wallis test. RESULTS: The mean shear bond strength of buccal tubes to enamel, ceramic and zirconia surfaces bonded with Assure plus and Enhance LC was highest for enamel followed by zirconia surfaces respectively. Non-parametric Kruskal-Walli’s test found significant differences regarding the shear bond strength and adhesive remnant index (ARI). CONCLUSION: Bonding of buccal tubes to enamel, zirconia, and ceramic surfaces with Assure universal bonding resin and Enhance LC provided adequate bond strength. Thus, it may be used for bonding of orthodontic buccal tubes to the artificial crown surfaces in the clinical setting.
{"title":"Comparative Evaluation Of The Shear Bond Strength Of Two Different Orthodontic Bonding Agents On Artificial Crown Surfaces: An Invitro Study","authors":"Priyanka Polineti, Anoosha Manda, Pradeep Kandikatla, Padma priya C.V, Praveen Kumar Varma Datla, Venkata Durga Mahendra Tivanani, Sai Keerthi Velagala","doi":"10.56501/intjorthodrehabil.v14i2.781","DOIUrl":"https://doi.org/10.56501/intjorthodrehabil.v14i2.781","url":null,"abstract":"INTRODUCTION: Bonding of buccal tubes to the tooth is an essential procedure in orthodontic treatment. With the increase in the number of adult patients seeking fixed orthodontic treatment, there is a need to find a more reliable procedure to bond the artificial crown surface. Successful orthodontic treatment requires sufficiently high and durable bond between buccal tubes and ceramic/zirconia surfaces. There is a need for a bonding agent which can provide maximum bond strength to all surfaces. This study aimed to assess and compare the shear bond strength and adhesive remnants of orthodontic buccal tubes to natural teeth, ceramic crowns and zirconia crowns using two different bonding systems. METHODS: In this in vitro study, 60 extracted human molar teeth were randomly assigned to three groups (n=20) and then divided into two subgroups(n=10). Bonding of buccal tubes to enamel, ceramic and zirconia surfaces was done using Assure plus universal bonding resin and Enhance LC. The shear bond strength of buccal tubes to the enamel, ceramic and zirconia surfaces were determined by universal testing machine. The SBSs and ARI scores were statistically analysed with and Kruskal Wallis test. RESULTS: The mean shear bond strength of buccal tubes to enamel, ceramic and zirconia surfaces bonded with Assure plus and Enhance LC was highest for enamel followed by zirconia surfaces respectively. Non-parametric Kruskal-Walli’s test found significant differences regarding the shear bond strength and adhesive remnant index (ARI). CONCLUSION: Bonding of buccal tubes to enamel, zirconia, and ceramic surfaces with Assure universal bonding resin and Enhance LC provided adequate bond strength. Thus, it may be used for bonding of orthodontic buccal tubes to the artificial crown surfaces in the clinical setting.","PeriodicalId":29888,"journal":{"name":"International Journal of Orthodontic Rehabilitation","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135260657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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