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A very rare fact occurring after V/P shunt in the surgical treatment of Pseudotumor Serebri Syndrome 在假瘤Serebri综合征的外科治疗中,V/P分流后发生的一个非常罕见的事实
Pub Date : 2021-12-21 DOI: 10.33962/roneuro-2021-078
Mehmet Akif Ambarcioglu, İ. Atcı, Okan Türk, V. Antar, N. Demirel, N. Özdemir, Emre Eğilmez, A. Karaoğlu, Ö. Baran
Introduction: In this study, it is aimed to present a very rare liver subcapsular accumulation of a patient after ventriculoperitoneal shunt surgery who was diagnosed with Pseudotumor cerebri syndrome with progressive sight loss.     Case: The patient is a 38-year-old female who was diagnosed with lomber spondylose and later operated with stabilization and fusion surgery. Seven days after the operation her headaches became clear and blackout in her left eye was seen and she was observed with medical treatment. CSF  pressure of her was measured to be 25 cm/ water, so she was diagnosed as pseudotumour cerebri and taken to the operation immediately. On the 3rd day of post-operation, there occurred to be intense stomach ache and abdominal sensitivity of the case. After the scanning of abdominal CT,  7 cm of liquid collection was detected in the shunt distal of liver subcapsular area. Discussion: Liver pseudocyst should be considered, even if it is a rare complication when back striking abdominal pain and high liver enzymes are seen in patients with shunt dysfunction. USG and abdominal bt tests should be made for these patients. The drainage of the cyst and then the removal of the abdominal catheter should be applied.
引言:在这项研究中,旨在介绍一名在脑室-腹腔分流术后被诊断为伴有进行性视力丧失的大脑假瘤综合征的患者的非常罕见的肝包膜下积聚。病例:患者是一名38岁的女性,被诊断为lomber脊椎病,后来进行了稳定和融合手术。手术七天后,她的头痛症状明显,左眼出现昏厥,并接受了药物治疗。测量她的脑脊液压力为25厘米/水,因此她被诊断为大脑假性肿瘤,并立即接受手术。术后第3天,患者出现剧烈腹痛和腹部敏感。在腹部CT扫描后,在肝包膜下区域的分流远端检测到7cm的液体收集。讨论:肝假性囊肿应该考虑,即使它是一种罕见的并发症,当分流功能障碍的患者出现背痛和高肝酶时。这些患者应进行USG和腹部bt测试。应先引流囊肿,然后取出腹腔导管。
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引用次数: 0
Postoperative lumbar spondylodiscitis 术后腰椎间盘炎
Pub Date : 2021-12-21 DOI: 10.33962/roneuro-2021-074
Anamaria-Alexandra Arsene, I. Gabriel, A. Ciurea
Background. Several causes that can trigger POD can be incriminated: the patient's immune status, surgical technical errors, intra-operative contamination, foreign materials microfilm. Extensive analysis is required to eradicate the limited or diffuse infection and manage the optimal therapeutic attitude conservative or by surgery to get: faster recovery time, to improve symptoms, to allow mobilization, to offer a good quality of life and to reduce the average length of hospital stay. Objectives. To perform a systematic review of POD outcomes via retrospective analysis of current studies based on the mechanism, the pathogenesis, the management of patient's immunological status, aetiology (microorganism involved, foreign material applied for hemostasis, application of spinal instrumentation, cement, screws, spinal devices), laboratory (TLC, ESR, CRP), MRI/CT-scan, antibiotherapy guidelines and the type of surgery performed: classical or minim-invasive, length of procedure, intraoperative accidents, the experience of the neurosurgeon, post-operative stay in ICU, etc. Methods. Several data were taken into account regarding lumbar infections using a comprehensive review of the literature published studies from 1998 to 2021. Demographic data, clinical variables, length of hospital stay, duration of antibiotic treatment, and post-treatment complications were assessed. Results. We performed a systematic review concerning 31 studies regarding clinical status, diagnosis and treatment. Conclusions. Based on our systematic analysis, training and continuous education in spine surgery are necessary to prevent POD. The diagnosis of lumbar POD is based on history and physical examination, biochemical markers, neuroradiologic studies, using appropriate MRI imaging. Most cases of lumbar POD can be managed by conservative treatment with antibiotics after causative germ isolation and antibiogram. Surgery is performed on patients with conservative treatment failure - resistant to antibiotic therapy, as those with neurological complications: acute paraplegia, pain resistance to analgetics, acute sepsis, abscesses, spinal instability, severe kyphosis. Early surgery with wound irrigation/debridement is more readily able to disrupt biofilm formation and facilitate penetration of systemic antimicrobials to allow for resolution of the infection, vacuum-assisted closure facilitates wound healing and eradicates spinal infections, decrease the rate of complications, permit rapid pain relief while preserving the instrumentation/stability, better clinical outcomes, infection control before extensive destruction of the vertebrae, spinal instability and kyphotic deformity appear. Instrumentation can usually be preserved in patients with early infections (e.g., <6 weeks), but instrumentation removal should be considered for infections presenting in a delayed fashion (e.g., >6 weeks to even years) PSII. Patients should be adequately followed for one postoperative year, to ensu
背景可能引发POD的几个原因可能会被定罪:患者的免疫状态、手术技术错误、术中污染、异物缩微胶片。需要进行广泛的分析,以根除局限性或弥漫性感染,并采取保守或手术的最佳治疗态度:更快的恢复时间,改善症状,允许动员,提供良好的生活质量,并缩短平均住院时间。目标。通过对当前研究的回顾性分析,对POD结果进行系统回顾,这些研究基于机制、发病机制、患者免疫状态的管理、病因(涉及的微生物、用于止血的异物、脊柱器械、水泥、螺钉、脊柱器械的应用)、实验室(TLC、ESR、CRP)、MRI/CT扫描,抗生素治疗指南和手术类型:经典或微创、手术时间、术中事故、神经外科医生的经验、术后在ICU的停留时间等。方法。通过对1998年至2021年发表的文献研究的全面回顾,考虑了一些关于腰椎感染的数据。评估人口统计学数据、临床变量、住院时间、抗生素治疗持续时间和治疗后并发症。后果我们对31项关于临床状态、诊断和治疗的研究进行了系统综述。结论。根据我们的系统分析,脊柱外科的培训和继续教育是预防POD的必要条件。腰椎POD的诊断基于病史和体格检查、生化标志物、神经放射学研究,并使用适当的MRI成像。大多数腰椎POD病例可以在病原菌分离和抗体谱后用抗生素进行保守治疗。手术治疗对抗生素治疗有耐药性的保守治疗失败患者,如有神经系统并发症的患者:急性截瘫、对止痛药的耐药性、急性败血症、脓肿、脊柱不稳定、严重后凸。伤口冲洗/清创术的早期手术更容易破坏生物膜的形成,促进全身抗菌药物的渗透,以解决感染,真空辅助闭合促进伤口愈合,根除脊椎感染,降低并发症发生率,允许快速缓解疼痛,同时保护器械/稳定性,更好的临床效果,在广泛破坏脊椎、脊柱不稳定和后凸畸形出现之前控制感染。早期感染(例如,6周甚至几年)PSII的患者通常可以保留器械。患者应充分随访一年,以确保感染已完全根除。植入超声处理提供了用于直接鉴定活性和/或持久性生物膜的培养物,而引入溶解生物膜基质的酶(例如DNA酶和藻酸盐裂解酶)和增加生物膜对抗生素易感性的群体感应抑制剂可以进一步帮助管理术后感染(2)(27-31)。
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引用次数: 0
T- configuration stent assisted coiling treatment of a complex wide-necked basilar tip aneurysm T形支架辅助盘绕治疗复杂的宽颈基底动脉瘤
Pub Date : 2021-12-21 DOI: 10.33962/roneuro-2021-068
A. Chiriac, N. Dobrin, G. Ion, Z. Faiyad, A. Iencean, I. Poeată
The advancement of intracranial stent technology and techniques has extended the applications of endovascular coiling methods for complex intracranial aneurysms. Coiling of wide-necked and complex bifurcation aneurysms usually requires double stent implantation. Different configurations for double stent-assisted coil embolization have been described. The T-configuration stent-assisted coiling procedure was recently described as a feasible, effective, and relatively safe endovascular technique used to treat wide-necked complex bifurcation aneurysms. In this article, we present the successful management of a complex wide-neck basilar tip aneurysm using a slightly modified T-configuration stent-assisted coiling technique.
颅内支架技术和工艺的进步,扩大了血管内盘绕方法在复杂颅内动脉瘤中的应用。宽颈和复杂分叉动脉瘤的盘绕通常需要双支架植入。不同的配置双支架辅助线圈栓塞已被描述。t形支架辅助盘绕术最近被认为是一种可行、有效且相对安全的血管内技术,用于治疗宽颈复杂分叉动脉瘤。在这篇文章中,我们介绍了使用稍微改进的t形支架辅助卷绕技术成功治疗复杂的宽颈基底动脉尖端动脉瘤。
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引用次数: 0
The complementary multimodal treatment of recalcitrant cerebral aneurysms 多模式互补治疗顽固性脑动脉瘤
Pub Date : 2021-12-21 DOI: 10.33962/roneuro-2021-076
M. Deniwar, M. Kassem, Ashraf Ezzeldin, J. Jafar
Background: The main treatment of cerebral aneurysms is direct surgical clipping or endovascular coil embolization. However, some cerebral aneurysms that we reviewed in the literature are still not susceptible to a single treatment approach. These aneurysms can be referred to as complex aneurysms. Objective:  We aim to report these aneurysms and share our clinical experience with their treatment and diagnosis. Methods: All cases of cerebral aneurysms treated in New York University and in Mansoura University from 2010-2021 were retrospectively reviewed. Results: 18 patients with 21 cerebral aneurysms were treated by combined surgical and endovascular modalities. Aneurysms associated with arteriovenous malformations (AVMs) in 3 patients, associated with vasospasm in 7 patients, and 3 patients had double aneurysms. A total of 18 patients with aneurysms were treated with combined endovascular and microsurgical therapy. Early angiogram (< 1 week) revealed; complete obliteration of 19 aneurysms (90%) out of a total of 21 aneurysms, residual filling was observed in 2 aneurysms (10%). Late radiological follow up (> 3 months- 2 years) revealed; a stable residual filling in one and the other case underwent retreatment. Conclusions: The recalcitrant or complex cerebral aneurysms can be better referred to as diseases rather than lesions as many clinical and anatomical factors make their treatment difficult. Endovascular and microsurgery could be complementary to each other and create a multimodal approach for treating them.
背景:脑动脉瘤的主要治疗方法是直接手术夹闭或血管内栓塞。然而,我们在文献中回顾的一些脑动脉瘤仍然不易受到单一治疗方法的影响。这些动脉瘤可以称为复杂动脉瘤。目的:报告这些动脉瘤,并分享我们对其治疗和诊断的临床经验。方法:回顾性分析2010-2021年在纽约大学和曼苏拉大学治疗的所有脑动脉瘤病例。结果:18例21个脑动脉瘤患者采用手术和血管内联合治疗。动脉瘤伴动静脉畸形3例,伴血管痉挛7例,双动脉瘤3例。共有18例动脉瘤患者接受了血管内和显微外科联合治疗。早期血管造影(<1周)显示;21个动脉瘤中有19个(90%)动脉瘤完全闭塞,2个(10%)动脉瘤有残余充盈。晚期放射学随访(>3个月-2年)显示;其中一例残余填充物稳定,另一例进行了再治疗。结论:顽固性或复杂的脑动脉瘤可以更好地称为疾病,而不是病变,因为许多临床和解剖因素使其治疗困难。血管内和显微外科手术可以相互补充,并创造一种多模式的治疗方法。
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引用次数: 0
The importance of Nuclear Magnetic Resonance (MRI) in the diagnosis of cerebral cavernomas 核磁共振(MRI)在诊断脑海绵状瘤中的重要性
Pub Date : 2021-12-21 DOI: 10.33962/roneuro-2021-070
Daniela C Bentia, A. Marinescu, F. Papagheorghe, Georgeta Popa, A. Ciurea
Introduction: Cavernomas are one of the four types of vascular malformations which develop in the central nervous system. From an imaging point of view, they are low flow small vessel malformations that cannot be seen on conventional angiography and are rarely visible on CT. They can be seen on MRI because of the para-magnetic haemoglobin break-down products within them. Case presentation: A 35 years old male presented at the emergency room following a tonic-clonic seizure, without urine emission. After a clinical exam, it was decided to perform a cerebral MRI with contrast substance and angiographic sequence. Clinical and imagistic results showed a superficial left temporal cavernoma, which showed signs of recent bleeding. After the surgery, the patient has no neurological deficits and is discharged afebrile and without any other symptoms. At 6 weeks after the surgery, the patients returned for neurosurgical reevaluation in perfect neurological condition, without motor deficit or intracranial hypertension. Conclusions: Cavernomas are angiographic cryptic vascular lesions that need an MRI investigation in order to appreciate them correctly.
海绵状血管瘤是发生在中枢神经系统的四种血管畸形之一。从影像学的角度来看,它们是低流量的小血管畸形,在常规血管造影上看不到,在CT上也很少可见。在MRI上可以看到它们,因为它们内部有准磁性的血红蛋白分解产物。病例介绍:一名35岁男性,因强直阵挛性癫痫发作,无排尿而被送往急诊室。临床检查后,决定进行脑MRI造影剂和血管造影序列。临床及影像学结果显示一浅表左侧颞海绵状瘤,并有近期出血的征象。手术后,患者无神经功能缺损,出院时无发热,无其他症状。术后6周,患者返回行神经外科再评估,神经功能完全,无运动障碍或颅内高压。结论:海绵状瘤是一种血管造影下的隐性血管病变,需要MRI检查才能正确识别。
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引用次数: 0
Imaging characteristics, histopathological features and surgical considerations regarding aggressive meningiomas 侵袭性脑膜瘤的影像学特征、组织病理学特征和手术注意事项
Pub Date : 2021-12-21 DOI: 10.33962/roneuro-2021-073
G. Popescu, F. Paslaru, A. Paslaru, M. Apostol, M. Zaharia, T. Corneliu, M. Mitrica, M. Popescu, R. M. Gorgan
Meningiomas are tumours of the meninges that arise primarily from arachnoidal cap cells, but they can also occur rarely as primary tumours in other localizations, such as within the ventricles. They stand for 24-30% of primary intracranial tumours and affect mostly women in their middle age or later adult life [1, 2]. Meningiomas can be classified, according to the World Health Organization (WHO) classification of Central Nervous System (CNS) tumours, as benign (grade I, most frequently encountered type), atypical (grade II) or anaplastic (grade III), based mostly on histopathological criteria known to be associated with tumour progression, recurrence risk and survival. Since meningioma grading based on the WHO classification is the most important factor determining therapeutic management and tumour prognosis, there has been an increasing interest in adding new criteria for better characterization of these tumours. Thus, the 2016 edition of the WHO classification recognized brain invasion as an independent criterion for atypical (grade II) meningioma diagnosis [3]. However, meningiomas that display aggressive features such as rapid growth and higher recurrence rate, can also involve blood vessels and bone. Hence, the authors aim to describe a different entity, aggressive meningiomas, not previously listed as a tumour phenotype in the WHO classification of meningothelial-cell tumours, with regard to pre-, intra- and postoperative methods for diagnosis and explore the implications on surgical strategies and adjuvant therapy.
脑膜瘤是主要由蛛网膜帽细胞引起的脑膜肿瘤,但在其他部位,如脑室内,它们也很少作为原发性肿瘤发生。它们占原发性颅内肿瘤的24-30%,主要影响中年或成年后的女性[1,2]。根据世界卫生组织(世界卫生组织)对中枢神经系统(CNS)肿瘤的分类,脑膜瘤可分为良性(I级,最常见类型)、非典型(II级)或间变性(III级),主要基于已知与肿瘤进展、复发风险和存活相关的组织病理学标准。由于基于世界卫生组织分类的脑膜瘤分级是决定治疗管理和肿瘤预后的最重要因素,因此增加新的标准以更好地表征这些肿瘤的兴趣越来越大。因此,2016年版世界卫生组织分类将脑侵袭作为非典型(II级)脑膜瘤诊断的独立标准[3]。然而,表现出侵袭性特征的脑膜瘤,如快速生长和较高的复发率,也可能涉及血管和骨骼。因此,作者旨在描述一种不同的实体,侵袭性脑膜瘤,在世界卫生组织的脑膜瘤细胞肿瘤分类中未被列为肿瘤表型,涉及术前、术中和术后的诊断方法,并探讨其对手术策略和辅助治疗的影响。
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引用次数: 0
Outcome of patients undergoing posterior spine fixation and decompression for posttraumatic thoracolumbar spine fractures and the factors predicting it 创伤后胸腰椎骨折后路脊柱固定减压的疗效及预测因素
Pub Date : 2021-12-21 DOI: 10.33962/roneuro-2021-077
G. Jose, T. Abraham, P. Balakrishnan, Muhammed P.S. Irphan, T.P. Haris, Vala Parth Prakashbhai
Background: Posterior spine fixation and decompression for thoracic and lumbar spine fractures have the advantage of stabilization of the fracture, decompression of neural canal, early mobilization and rehabilitation of the patient. The study aimed to find out the postoperative outcome and complications following posterior spine surgery and the factors affecting the outcome. Methods: A retrospective study was carried out among 44 patients who underwent posterior spine decompression and fusion for thoracic and lumbar spine fracture. The data regarding patient presenting symptoms, comorbidity, associated injuries and imaging finding in CT and MRI were collected. The postoperative outcome of patients after surgery was assessed using ASIA impairment scale, KPS, VAS scale for pain are noted at the preoperative and postoperative period. Other factors like improvement of bowel and bladder symptoms, back stiffness and return to the job after surgery were also found out. Results: There was a significant improvement in ASIA impairment scale (mean =0.74 grade), KPS score (mean = 40) and VAS pain scale (mean = 6.7) at 6 months follow up after surgery. Improvement in ASIA impairment scale was more in the patient with severe canal compromise (mean = 1.62 grade), patients with translational/ distraction injuries (mean= 1.01grade) and patients with paraparesis (mean=1.06). Only one-third of patients with bowel and bladder involvement improved after surgery. Around 56.8% of patients were able to return to jobs at 6 months follow up. Patients who were paraplegic at the initial presentation were mostly not able to return to jobs. The most common reported complication in the study was intraoperative pedicle breakage. Conclusion: Decompression of the spinal cord plus posterior spine fixation is a safe, reliable and effective method in the management of thoracic and lumbar fractures with significant improvement in outcome in terms of motor power, pain and quality of life.
背景:胸腰椎骨折后路固定减压具有骨折稳定、神经管减压、患者早期活动和康复的优点。本研究旨在了解脊柱后部手术的术后结果、并发症以及影响结果的因素。方法:对44例胸腰椎骨折患者进行回顾性分析。收集有关患者症状、合并症、相关损伤以及CT和MRI影像学发现的数据。使用ASIA损伤量表评估患者术后的结果,KPS、VAS量表在术前和术后记录疼痛情况。还发现了其他因素,如排便和膀胱症状的改善、背部僵硬和术后重返工作岗位。结果:术后6个月随访时,ASIA损伤量表(平均值=0.74级)、KPS评分(平均值=40)和VAS疼痛量表(均值=6.7)均有显著改善。严重椎管损伤(平均1.62级)、平移/牵张损伤(平均1.01级)和轻瘫患者(平均1.06级)的ASIA损伤量表改善较多。只有三分之一的肠和膀胱受累患者在手术后有所改善。在6个月的随访中,约56.8%的患者能够重返工作岗位。最初表现为截瘫的患者大多无法重返工作岗位。研究中最常见的并发症是术中椎弓根断裂。结论:脊髓减压加脊柱后固定是治疗胸腰椎骨折的一种安全、可靠、有效的方法,在运动能力、疼痛和生活质量方面有显著改善。
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引用次数: 0
Postoperative complications in endoscopic frontal transcortical surgery of lateral and third ventricle tumours 内镜下额部经皮质手术治疗侧脑室及第三脑室肿瘤的术后并发症
Pub Date : 2021-12-15 DOI: 10.33962/roneuro-2021-088
O. Palamar, A. Huk, R. Aksyonov, D. Teslenko, D. Okonskyi, Nazarii V. Lazko
Neurosurgical approaches to lesions of the lateral and the third ventricles are divided into two fundamentally different groups: transcortical neurosurgical approaches, including - endoscopic and interhemispheric transcallosal microneurosurgical approaches. Complications in surgery of lateral and third ventricle tumours are often associated with the specific approach technique and could be transient. We analyzed postoperative neurological complications and the approach criteria on MRI or CT scans in postoperative period such as localization of corticotomy, distance from corticotomy to coronal suture, “angle of attack” after the frontal transcortical approach to the lateral and third ventricle based on 54 cases and presume transient nature of specific to approach complications and approaches’ factors that have role in postoperative mutism.    
侧脑室和第三脑室病变的神经外科手术方法分为两组:经皮质神经外科手术方法,包括内窥镜和半球间经同种异体显微神经外科手术方法。侧脑室和第三脑室肿瘤手术的并发症通常与特定的入路技术有关,并且可能是短暂的。我们分析了术后神经系统并发症和术后MRI或CT扫描的入路标准,基于54例经皮质额侧脑室和第三脑室入路后的“攻击角度”,并推测出特定入路并发症的短暂性和入路因素在术后缄默症中的作用。
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引用次数: 1
Surgical smoke, neurosurgical practice and coronavirus 手术烟雾、神经外科实践与冠状病毒
Pub Date : 2021-12-15 DOI: 10.33962/roneuro-2021-081
Adesh Shrivastava, N. Maria, Rakesh Mishra, W. Florez-Perdomo, A. Agrawal, L. Moscote-Salazar
Surgical smoke also referred to as cautery smoke is a gaseous mixture produced during surgical procedures where there is ablation, cutting, coagulation, desiccation or vaporization of the tissue.  In a true sense "surgical smoke” refers to surgically generated gaseous contents. The surgical smoke results from the destruction of bones and tissues, causing microscopic particles to get suspended in the environment. 
手术烟雾也称为烧灼烟雾,是在组织消融、切割、凝固、干燥或蒸发的手术过程中产生的气体混合物。真正意义上的“手术烟雾”是指手术产生的气体。手术烟雾是由于骨骼和组织的破坏,导致微观颗粒悬浮在环境中。
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引用次数: 0
Multimodal neurological monitoring in neurotrauma 神经损伤的多模式神经监测
Pub Date : 2021-12-15 DOI: 10.33962/roneuro-2021-091
Randy Reina-Rivero, M. Rodríguez-Gutiérrez, Michael Gregorio Ortega Sierra, Diego Fernando Jamioy-Cabrera, Juan Felipe Villegas-Lora, Daniela Margoth Caycedo-Montiel, Juan David Balanta-Perea, Richard Adrian Vergara-Trujillo, Fernando Bellera, Y. Picón-Jaimes
Multimodal neuromonitoring is used as an adjunct to clinical neurological examination, imaging and other diagnostic studies to obtain the most detailed information about the physiology of the brain. Neuromonitoring has been a standard of care for patients presenting with traumatic brain injury in most critical care centres for the past several years. Neuromonitoring is composed of multiple variables, which not only provides a better dynamic of the pathophysiology of the compromised brain but also how it might respond to the corresponding management procedures. Although the clinical neurological examination is the standard for monitoring the neurocritical patient, the results obtained in the latter may be insufficient or inconclusive to detect or prevent secondary brain injury. Therefore, multiple neuromonitoring tools have been developed to measure different physiological variables that can contribute to a better follow-up of patients with traumatic brain injury. These variables include cerebral blood flow, cerebral electrical activity, cerebral metabolism, cerebral oxygenation and cerebral pressure. Thanks to monitoring as an adjuvant in critical care, it has been possible to avoid, identify and manage secondary brain injuries that commonly aggravate patients. This review aims to illustrate the main advantages and most recent recommendations regarding neuromonitoring based on the most current evidence.
多模式神经监测被用作临床神经检查、成像和其他诊断研究的辅助手段,以获得有关大脑生理学的最详细信息。在过去的几年里,神经监测一直是大多数重症监护中心对创伤性脑损伤患者的标准护理。神经监测由多个变量组成,不仅可以更好地了解受损大脑的病理生理学,还可以了解其对相应管理程序的反应。尽管临床神经系统检查是监测神经危重患者的标准,但后者的结果可能不足以或不确定,无法检测或预防继发性脑损伤。因此,已经开发了多种神经监测工具来测量不同的生理变量,这有助于更好地跟踪创伤性脑损伤患者。这些变量包括脑血流量、脑电活动、脑代谢、脑氧合和脑压力。由于监测作为重症监护的辅助手段,可以避免、识别和管理通常会加重患者的继发性脑损伤。这篇综述旨在说明基于最新证据的神经监测的主要优势和最新建议。
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引用次数: 0
期刊
Romanian Neurosurgery
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