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Global neurosurgery: the need of the hour for developing countries 全球神经外科:发展中国家的时代需要
Pub Date : 2023-03-15 DOI: 10.33962/roneuro-2023-020
Ahtesham Khizar, Soha Zahid
Global neurosurgery is relatively a new sub-discipline of global surgery. It is an area of study, research, practice, and advocacy that focuses on enhancing health outcomes and promoting health equity for all individuals around the world who are afflicted by neurosurgical disorders or require neurosurgical care. Low- and middle-income countries (LMICs) around the world have not benefited from advances in neurosurgery; most have little or no neurosurgical capacity in their entire country. The need of the hour is that a global problem necessitates a global response with a common vision and objectives.
全球神经外科学是全球外科学中相对较新的分支学科。这是一个学习、研究、实践和宣传的领域,重点是提高世界各地所有受神经外科疾病折磨或需要神经外科护理的个人的健康结果和促进健康公平。世界各地的低收入和中等收入国家(LMICs)并没有从神经外科的进步中受益;大多数人在整个国家几乎没有神经外科能力。当前的需要是,一个全球性问题需要以共同的愿景和目标作出全球性反应。
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引用次数: 0
The efficacy of endoscopic endonasal duraplasty compared to transcranial duraplasty for post-traumatic CSF rhinorrhea in terms of CSF rhinorrhea recurrence and other complications 内镜下鼻内硬脑膜成形术与经颅硬脑膜成形术治疗创伤后脑脊液鼻漏在脑脊液鼻漏复发及其他并发症方面的疗效比较
Pub Date : 2023-03-15 DOI: 10.33962/roneuro-2023-014
Pranab Regmi, Ahtesham Khizar, Pradhumna Kumar Yadav
Objectives. To determine the efficacy of endoscopic endonasal dura repair versus transcranial dura repair for post-traumatic CSF rhinorrhoea in terms of CSF rhinorrhea recurrence and other complications. Materials and methods. A total of 92 patients (age 15-50 years, both genders) with an established diagnosis of CSF rhinorrhea following traumatic brain injury were enrolled in this prospective cohort study. Group A and Group B were formed from the patients. Group A received endoscopic endonasal duraplasty, while Group B received transcranial duraplasty. Recurrence of CSF rhinorrhea, as well as any other complications (meningitis, anosmia, hydrocephalus, and abscess), were noted and compared between the two groups one week, two weeks, and four weeks after the procedure. Results. In Group A, the mean age was 28.6 ± 9.9 SD years and in Group B it was 29.9 ± 8.6 SD years. In group A, there were 63% (n=29/46) patients who had age between 15-30 years and 37% (n=17/46) had age between 31-50 years. In group B, 52.2% (n=24/46) patients had age between 15-30 years and 47.8% (n=22/46) had age between 31-50 years. In group A, there were 82.6% (n=38/46) males and 17.4% (n=8/46) were females and in group B there were 87% (n=40/46) males and 13% (n=6/46) females. At one month follow-up, overall recurrence of rhinorrhea was observed in 17.4% (n=8/46) patients in Group A, while it was 41.3% (n=19/46) patients in Group B (P=0.012). On the other hand, overall complications were 8.7% (n=21/46) in Group A patients, while they were 45.7% (n=21/46) in Group B patients (P=0.001). Conclusions. During a one-month follow-up, patients who received endoscopic repair experienced fewer recurrences and other complications overall than patients who underwent transcranial duraplasty, and the difference was statistically significant. We advise conducting studies with a larger sample size and longer follow-up periods.
目标。比较经颅硬脑膜修复术与鼻内镜硬脑膜修复术治疗外伤性脑脊液鼻漏复发及其他并发症的疗效。材料和方法。这项前瞻性队列研究共纳入了92例确诊为外伤性脑损伤后脑脊液鼻漏的患者(年龄15-50岁,男女均可)。A组和B组由患者组成。A组行鼻内镜下硬脑膜成形术,B组行经颅硬脑膜成形术。观察两组患者术后1周、2周和4周脑脊液鼻漏的复发情况,以及其他并发症(脑膜炎、嗅觉丧失、脑积水和脓肿)。结果。A组患者平均年龄28.6±9.9 SD年,B组患者平均年龄29.9±8.6 SD年。在A组中,63% (n=29/46)的患者年龄在15-30岁之间,37% (n=17/46)的患者年龄在31-50岁之间。B组有52.2% (n=24/46)的患者年龄在15-30岁之间,47.8% (n=22/46)的患者年龄在31-50岁之间。A组男性占82.6% (n=38/46),女性占17.4% (n=8/46); B组男性占87% (n=40/46),女性占13% (n=6/46)。随访1个月,A组鼻漏总复发率为17.4% (n=8/46), B组为41.3% (n=19/46) (P=0.012)。A组总并发症发生率为8.7% (n=21/46), B组总并发症发生率为45.7% (n=21/46) (P=0.001)。结论。在一个月的随访中,接受内窥镜修复的患者总体上比接受经颅硬膜成形术的患者复发和其他并发症更少,差异有统计学意义。我们建议进行更大样本量和更长的随访期的研究。
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引用次数: 0
Secondary optic neuropathy due to sphenoid-ethmoidal sinus mucocele 蝶筛窦黏液膨出致继发性视神经病变
Pub Date : 2023-03-15 DOI: 10.33962/roneuro-2023-013
Khabibullo Khasanov, Gulnarakhon Alikhodjayeva, Jakhongir Yakubov, Ilkhom Khujanazarov
Secondary visual impairment induced by sinusitis is a rare condition that cannot be recognized in all cases. A steady decline in visual acuity and visual field together or alone is the main symptom patients may complain of on admission. This might be hard for general practitioners in Uzbekistan, as possible causes are either intracranial or ophthalmic abnormalities. Hence, it is frequently misdiagnosed or leads to late diagnosis once visual impairment becomes severe. In this paper, we discuss the case of a 9-year-old boy with impaired vision on the left side that was detected almost too late and could have led to complete vision loss. Ineffective conservative therapy was provided for four months. CT and MRI confirmed a lesion in the left sphenoethmoidal sinus. The patient then underwent endoscopic sphenoiethmodotomy with drainage of the left sphenoethmoidal sinus. In the early postoperative phase, as early as the next day after the surgical procedure, the patient experienced visual improvement. Forty days following surgery, in combination with postoperative conservative care in an eye hospital, there was a noticeable improvement in vision. In conclusion, it is crucial for ophthalmologists, neurologists, and ENT surgeons to focus on inflammation in the sphenoethmoidal sinus in children even with mild vision impairment.
鼻窦炎引起的继发性视力损害是一种罕见的情况,不能在所有病例中被识别出来。视力和视野持续下降是患者入院时主诉的主要症状。这对乌兹别克斯坦的全科医生来说可能很难,因为可能的原因是颅内或眼部异常。因此,一旦视力损害变得严重,它经常被误诊或导致晚期诊断。在本文中,我们讨论的情况下,一个9岁的男孩与左侧视力受损,发现几乎太迟,可能导致完全丧失视力。保守治疗无效4个月。CT和MRI证实左侧蝶筛窦病变。患者随后行内镜下蝶筛切开术并引流左侧蝶筛窦。在术后早期,早在手术后第二天,患者的视力就有所改善。术后40天,结合眼科医院的术后保守护理,视力有明显改善。总之,对于眼科医生、神经科医生和耳鼻喉外科医生来说,关注儿童蝶筛窦炎症是至关重要的,即使儿童有轻微的视力障碍。
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引用次数: 0
Preliminary results of minimally invasive stereotaxic surgery of intraparenchymal hematomas at the Hospital of Mali (23 cases) 马里医院微创立体定向手术治疗肺实质内血肿(23例)的初步结果
Pub Date : 2023-03-15 DOI: 10.33962/roneuro-2023-004
Mahamadou Dama, Oumar Diallo, Oumar Coulibaly, Daouda Sissoko, Theodore Maxim Coulibaly, Kalba Tembine, Thomas Coulibaly, Fengqiang Liu, Cisse El Hassimi Mohamed, Drissa Kanikomo
Introduction: Spontaneous intracerebral haemorrhage (ICH) is a rupture of blood vessels in the brain parenchyma, in the absence of any underlying structural vascular lesion. It’s destructive and associated with a high mortality rate. There is a specific threshold of hematoma evacuation to impact mortality or functional outcome in ICH even the curative effect of minimally invasive hematoma removal for cerebral haemorrhage has not been fully recognized worldwide. We aim to evaluate surgical performance on hematoma volume and functional outcomes of patients. Methods: This study is a retrospective and observational clinical study. A total of 30 ICH patients were treated in the Department of neurosurgery at the Hospital of Mali from December 2019 to November 2020. Minimal invasive puncture hematoma removal was performed in all the patients. The modified Rankin scale (mRS) was used to assess functional outcomes at 6 months and one year of surgery. Was considered poor functional outcome mRS >3. The percentages (%) of the count data were assessed by Fisher’s exact test by SPSS 23.0 software was used. Results: A total of 23 ICH patients met the inclusion criteria, the mean was 47,78 years. Among the risk factors, the HTA is present in 91,3% of patients. The evacuation was satisfactory in 91.30% of cases. Conclusion: This first study of minimally invasive stereotaxic for ICH evacuation must be followed up and encouraged. Even if the results are satisfactory, a double-blind study is required in the largest sample.
简介:自发性脑出血(ICH)是在没有任何潜在结构性血管病变的情况下,发生在脑实质的血管破裂。它是破坏性的,与高死亡率有关。脑出血血肿清除对死亡率或功能结局的影响有一个特定的阈值,即使微创脑出血血肿清除的疗效在世界范围内也没有得到充分的认可。我们的目的是评估手术对患者血肿量和功能结局的影响。方法:回顾性观察性临床研究。2019年12月至2020年11月,马里医院神经外科收治脑出血患者30例。所有患者均行微创穿刺血肿清除术。采用改良Rankin量表(mRS)评估手术6个月和1年的功能预后。被认为功能预后不良mRS >3。计数资料的百分比(%)采用Fisher精确检验,采用SPSS 23.0软件。结果:23例脑出血患者符合纳入标准,平均年龄47,78岁。在危险因素中,HTA存在于91.3%的患者中。91.30%的病例满意。结论:微创立体定向术用于脑出血清除术的首次研究必须予以随访和鼓励。即使结果令人满意,也需要在最大的样本中进行双盲研究。
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引用次数: 0
Conservative management of intraventricular migrating intracranial bullet 颅内子弹脑室内迁移的保守治疗
Pub Date : 2023-03-15 DOI: 10.33962/roneuro-2023-008
Amjed Hassan Saheb, Rania H. Al-Taie, Ibrahim A. Farooq, Abbas Musaab Taha, Hawraa Sadeq Naser, Zahraa Mohammed Yaseen, Mustafa Ismail, Samer S. Hoz
Background. The high mortality rate of a cranial bullet injury, the catastrophic damage of vital tissue, and the frequency of gunshot accidents made managing such cases highly effortful in neurosurgical trauma centres. One category of these injuries is the gravitational bullet injury, in which the bullet's movement depends on gravity after losing its kinetic energy. This paper aims to describe the conservative treatment plan we applied for a patient who suffered an intracranial gravitational bullet injury. Case description. The patient presented with a cranial bullet injury that migrated caudally to his lateral ventricle. This unapproachable location of the bullet made the surgical intervention undoable. Therefore, after the implication of resuscitative management, the patient went under heavy observation with a suitable follow-up plan. The patient's short-term outcome was excellent, and his Glasgow coma scale was 15 at the discharge. Conclusion. Conservative management in a gravitational bullet is one of the possible methods to reach the best outcome in non-operable patients. Such measures are highlighted in this case, even when a complication like a bullet migration may occur.
背景。脑部子弹伤的高死亡率、重要组织的灾难性损伤以及枪击事故的频繁发生,使得在神经外科创伤中心处理这类病例非常困难。其中一类是重力子弹伤,即子弹在失去动能后的运动依赖于重力。本文旨在描述我们对一例颅内重力子弹损伤患者所采用的保守治疗方案。案例描述。患者表现为头部子弹损伤,并向侧脑室迁移。子弹无法接近的位置使得手术无法进行。因此,在实施复苏治疗后,对患者进行了严密的观察,并制定了合适的随访计划。患者的短期预后很好,出院时格拉斯哥昏迷评分为15分。结论。对于不能手术的患者,保守治疗是达到最佳效果的可能方法之一。在这种情况下,这些措施是突出的,即使是像子弹迁移这样的并发症可能发生。
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引用次数: 0
Autologous versus synthetic cranioplasty 自体颅骨成形术与人工颅骨成形术比较
Pub Date : 2023-03-15 DOI: 10.33962/roneuro-2023-003
Arif Zafar, Samantha Strickland, Shailendra Achawal
Background. Cranioplasty has been described in history as far back as the 16th century. The use of autologous cranioplasty has been published since 1821 and is still under practice today worldwide. Recent evidence however has suggested increased complication and revision rates with the use of autologous bone. We compared our results of autologous cranioplasty versus synthetic material. Methods. A retrospective study was carried out of cranioplasty procedures at our unit between August 2009 and March 2018. Bone flaps were placed in a sterile sealed plastic container and stored at -81 degrees. Swabs and bone chips were used for cultures and bone flap disposed if positive. On re-implantation, the bone was thawed at room temperature and soaked in gentamicin. Synthetic cranioplasties were constructed using thin-slice CT to design a custom flap for each patient. Results. 144 cranioplasties were studied. 51 own bone and 93 synthetic. The average delay in cranioplasty was 286 days (Range 16 – 1264 days). The overall complication rate for all 144 cranioplasties was 20.8%; Autologous 31.4% and synthetic 15.1%; p 0.031. Bone flap infection rate overall for all 144 cases was 9.7% - Autologous 11.8% and Synthetic 8.6%; p 0.565. The revision rate was found to be 13.2% overall; 23.5% for autologous and 7.5% for synthetic. The difference in revision rate was found to be statistically significant (p 0.01). Conclusion. Revision rate and overall complication rate were higher in the own bone group with P<0.05. There was no difference in infection. Our results mirror recent publications and should be considered when undertaking a cranioplasty.
背景。历史上对颅骨成形术的描述可以追溯到16世纪。自1821年以来,自体颅骨成形术的使用已经发表,并且至今仍在世界范围内实践。然而,最近的证据表明自体骨的使用增加了并发症和翻修率。我们比较了自体颅骨成形术和合成材料成形术的结果。方法。2009年8月至2018年3月期间,我们单位对颅骨成形术进行了回顾性研究。骨瓣放置在无菌密封塑料容器中,在-81度保存。拭子和骨片用于培养,如果阳性则处理骨瓣。再植入时,骨在室温下解冻并浸泡在庆大霉素中。利用薄层CT为每位患者设计定制皮瓣构建合成颅骨成形术。结果:144例颅骨成形术。51是自己的骨头,93是合成的。颅骨成形术的平均延迟时间为286天(范围16 - 1264天)。144例颅骨成形术的总并发症发生率为20.8%;自体31.4%,合成15.1%;0.031 p。144例骨瓣总体感染率为9.7%,自体骨瓣为11.8%,合成骨瓣为8.6%;0.565 p。总体修正率为13.2%;自体23.5%,合成7.5%。复习率差异有统计学意义(p < 0.01)。结论。自骨组翻修率和总并发症发生率均高于P<组;0.05。感染方面没有差异。我们的结果反映了最近的出版物,在进行颅骨成形术时应予以考虑。
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引用次数: 0
Influence of clinical and neurophysiological parameters on the function outcome of the facial nerve after vestibular schwannoma surgery 临床及神经生理参数对前庭神经鞘瘤术后面神经功能预后的影响
Pub Date : 2023-03-15 DOI: 10.33962/roneuro-2023-006
Dražen Radanović, Rosanda Ilić, Ivan Bogdanović, Bojana Živković, Srbislav Pajić, Magdalena Nikolić, Đurđina Bogosavljević
Introduction: Vestibular schwannomas are benign neoplasms of the nerve seath, and they represent the third most common endocranial tumour, following the meningioma and the pituitary adenomas. The primary symptoms of vestibular schwannomas are hearing loss, tinnitus as well as a balance disorder. The therapy of vestibular schwannoma consists of observation, surgery and radiosurgery. The majority of patients who are good candidates for surgery are already affected by significant hearing impairment, thus one of the primary goals of the surgery is the preservation of facial nerve function. Aim: To analyze the outcome of facial nerve function one-year post-surgery using clinical and neuropsychological parameters. Material and methods: This study analyzed the patient's clinical status on admission along with the neuroradiological characteristics of tumours and the neurophysiological intraoperative parameters and their effect on the facial nerve function in the early postoperative period as well as one year after the surgery using the House–Brackmann scale. Results: A total of 30 patients who underwent surgery from January 1st 2015 to December 31st 2018 at the Clinical Centre of Serbia, Neurosurgery Clinic for vestibular schwannomas were examined. The median age of the patients was 51 years. Hearing loss was present in all patients. Sensitivity drop in the innervation region of n. trigeminus was present in 7 (23.3%) patients, as was tinnitus. Cerebellar symptomatology (76%) was present in the highest percentage of patients. Conclusion: We can conclude that the most important aspects of the facial nerve function are the preoperative state of the facial nerve and the electrophysiological parameters. Although the radical procedure of surgery led to an immediate postoperative outcome, it was not significant for the ultimate outcome of treatment. Thus, radical surgery may be considered to carry the same risk of definitive impairment of the facial nerve function, just like a combination treatment with subtotal resection and stereotaxic radiosurgery.
导言:前庭神经鞘瘤是神经鞘的良性肿瘤,是继脑膜瘤和垂体腺瘤之后第三常见的颅内肿瘤。前庭神经鞘瘤的主要症状是听力丧失、耳鸣以及平衡障碍。前庭神经鞘瘤的治疗包括观察、手术和放疗。大多数适合手术的患者已经受到严重的听力障碍的影响,因此手术的主要目标之一是保留面神经功能。目的:分析术后1年面神经功能的临床及神经心理学指标。材料与方法:本研究采用House-Brackmann量表分析患者入院时的临床状况、肿瘤的神经放射学特征、术中神经生理参数及其对术后早期及术后1年面神经功能的影响。结果:对2015年1月1日至2018年12月31日在塞尔维亚临床中心神经外科诊所接受前庭神经鞘瘤手术的30例患者进行了检查。患者的中位年龄为51岁。所有患者均有听力损失。三叉神经神经支配区敏感性下降7例(23.3%),耳鸣患者亦如此。小脑症状(76%)出现在比例最高的患者中。结论:术前面神经状态和电生理参数是影响面神经功能的最重要因素。虽然根治性手术可立即获得术后结果,但对最终治疗结果无显著影响。因此,可以认为根治性手术与次全切除和立体定向放射手术联合治疗一样,具有面神经功能明确损害的风险。
{"title":"Influence of clinical and neurophysiological parameters on the function outcome of the facial nerve after vestibular schwannoma surgery","authors":"Dražen Radanović, Rosanda Ilić, Ivan Bogdanović, Bojana Živković, Srbislav Pajić, Magdalena Nikolić, Đurđina Bogosavljević","doi":"10.33962/roneuro-2023-006","DOIUrl":"https://doi.org/10.33962/roneuro-2023-006","url":null,"abstract":"Introduction: Vestibular schwannomas are benign neoplasms of the nerve seath, and they represent the third most common endocranial tumour, following the meningioma and the pituitary adenomas. The primary symptoms of vestibular schwannomas are hearing loss, tinnitus as well as a balance disorder. The therapy of vestibular schwannoma consists of observation, surgery and radiosurgery. The majority of patients who are good candidates for surgery are already affected by significant hearing impairment, thus one of the primary goals of the surgery is the preservation of facial nerve function. Aim: To analyze the outcome of facial nerve function one-year post-surgery using clinical and neuropsychological parameters. Material and methods: This study analyzed the patient's clinical status on admission along with the neuroradiological characteristics of tumours and the neurophysiological intraoperative parameters and their effect on the facial nerve function in the early postoperative period as well as one year after the surgery using the House–Brackmann scale. Results: A total of 30 patients who underwent surgery from January 1st 2015 to December 31st 2018 at the Clinical Centre of Serbia, Neurosurgery Clinic for vestibular schwannomas were examined. The median age of the patients was 51 years. Hearing loss was present in all patients. Sensitivity drop in the innervation region of n. trigeminus was present in 7 (23.3%) patients, as was tinnitus. Cerebellar symptomatology (76%) was present in the highest percentage of patients. Conclusion: We can conclude that the most important aspects of the facial nerve function are the preoperative state of the facial nerve and the electrophysiological parameters. Although the radical procedure of surgery led to an immediate postoperative outcome, it was not significant for the ultimate outcome of treatment. Thus, radical surgery may be considered to carry the same risk of definitive impairment of the facial nerve function, just like a combination treatment with subtotal resection and stereotaxic radiosurgery.","PeriodicalId":30188,"journal":{"name":"Romanian Neurosurgery","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135748416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spontaneous complete resolution of a giant cavernous carotid aneurysm in the setting of ipsilateral ICA occlusion 在同侧颈内动脉闭塞的情况下,巨大海绵状颈动脉瘤的自发完全溶解
Pub Date : 2023-03-15 DOI: 10.33962/roneuro-2023-016
Sura H. Talib, Mayur Sharma, Vishan P. Ramanathan, Yara Alfawares, Muntadher H. Almufadhal, Mustafa Ismail, Samer S. Hoz
Background. Cavernous carotid aneurysms (CCA) are rare aneurysms with a relatively benign natural history. The association between CCA aneurysm and ipsilateral Internal carotid artery (ICA) thrombosis or occlusion has not been described previously. The management of patients with these dual lesions is a challenging problem. Case description. In this report, we describe an 18-year-old man who presented with left abducent nerve palsy of 3 weeks duration, and imaging revealed left CCA with left ICA occlusion. The patient was managed conservatively with clinical and imaging follow-up. The patient recovered well with complete resolution of clinical symptoms and disappearance of left CCA. Conclusions. The association of giant CCA and ICA occlusion on the same side is a rare phenomenon with no current consensus on the appropriate follow-up and management strategy. In this report, we described the first case of spontaneous complete disappearance of a giant CCA in the setting of ipsilateral ICA occlusion with complete resolution of symptoms at nine months of follow-up.
背景。海绵状颈动脉动脉瘤(CCA)是一种罕见的动脉瘤,具有相对良性的自然病史。CCA动脉瘤与同侧颈内动脉(ICA)血栓形成或闭塞之间的关系以前没有被描述过。这些双重病变患者的管理是一个具有挑战性的问题。案例描述。在本报告中,我们描述了一位18岁的男性,他表现为左侧外展神经麻痹,持续3周,影像学显示左侧CCA伴左侧ICA闭塞。对患者进行了保守治疗,并进行了临床和影像学随访。患者恢复良好,临床症状完全缓解,左侧CCA消失。结论。巨大CCA合并同侧ICA闭塞是一种罕见的现象,目前对适当的随访和治疗策略尚无共识。在本报告中,我们描述了第一例在同侧ICA闭塞情况下巨大CCA自发完全消失的病例,并在9个月的随访中症状完全缓解。
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引用次数: 0
Combined endoscopic-microscopic trans-nasal trans-sphenoidal approach for pituitary adenomas 经鼻蝶联合内镜入路治疗垂体腺瘤
Pub Date : 2023-03-15 DOI: 10.33962/roneuro-2023-015
Mohd Kaif, Kuldeep Yadav, Amit Upadhyay, Deepak Kumar Singh, Rakesh Kumar Singh, Ashish Chandra Agarwal, Kshitij Sinha
Objective. To obtain evidence that the use of endoscopy along with a microscope in the surgical management of pituitary tumours improves intraoperative visualization and significantly impacts operative outcomes in the trans-nasal approach. Material and methods. Each patient underwent endonasal transsphenoidal microscopic tumour resection. The procedure was modified by the use of intrasellar endoscopy as an adjunctive imaging modality. Following complete microscopic resection of tumour, rigid 0° and 30° 4.0-mm endoscopes were used to conduct a final survey of the sellar and parasellar spaces. Residual tumour fragments identified during this endoscopic examination were removed. Results. In 50 patients with pituitary macroadenomas, the rigid 30 ° angled rigid endoscope was found to be highly beneficial. Hidden areas could be visualized and tumour residues were detected. In the majority of the patients with detected tumour residues, adenomatous remnants were safely removed by meticulous endoscopic dissection under optimum visual control after the main part of the tumour had been removed with the operating microscope. Conclusions. Endoscopy provides distinct advantages over microscopy in imaging intrasellar and parasellar structures during pituitary tumour resection which are often missed by microscopy alone.
目标。在经鼻入路的垂体肿瘤手术中使用内镜和显微镜可以改善术中视觉效果并显著影响手术结果。材料和方法。每位患者均行鼻内经蝶窦显微肿瘤切除术。通过使用鞍内内窥镜作为辅助成像方式,对手术进行了改进。肿瘤完全显微切除后,使用刚性0°和30°4.0 mm内窥镜对鞍区和鞍旁间隙进行最后检查。在内窥镜检查中发现的残留肿瘤碎片被切除。结果。在50例垂体大腺瘤患者中,发现刚性30°角刚性内窥镜非常有益。可见隐藏区域,检测肿瘤残留。在大多数检测到肿瘤残留的患者中,在手术显微镜下切除肿瘤的主要部分后,在最佳视觉控制下,通过细致的内镜解剖安全地切除了腺瘤残留。结论。在垂体肿瘤切除术中,内窥镜在鞍内和鞍旁结构的成像上比显微镜具有明显的优势,而这些结构通常是单独用显微镜看不到的。
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引用次数: 0
Surgical management of spinal cord hemangioblastoma 脊髓血管母细胞瘤的外科治疗
Pub Date : 2023-01-05 DOI: 10.33962/roneuro-2022-075
George Popescu, Marius C. Zaharia, Andrei Giovani, Ioana Miron, Cezar Vîjlănescu, Radu M. Gorgan
Background. Hemangioblastomas are considered rare tumours that are located, in most cases, in the posterior cranial fossa. In most of cases, spinal hemangioblastomas are identified on the thoracic and cervical levels and can be associated in one-third of cases with von Hippel Lindau Syndrome. Material and methods. In this paper, we are presenting our clinic`s experience with spinal hemangioblastomas and the follow-up of the patients in the last 10 years. Results. In our study, we included six men and three women with a mean age of 45 years, ranging between 36 to 61 years. The mean hospitalization days was 17 days. Among nine patients, there were identified 12 tumors. Six patients presented cervical spine hemangioblastomas, two of them had thoracic spine lesions and in one case, the tumour was identified at the lumbar level. Furthermore, two patients presented multiple lesions. Two patients had been associated with von Hippel Lindau Syndrome. In all cases, surgery was the therapeutic approach. Discussions. Despite the rapid advance of technology and the new alternatives for the treatment of these lesions, surgical resection of hemangioblastomas remains the gold standard treatment. Conclusions. Hemangiolbastomas are benign tumours that can be associated with von Hippel Lindau. A whole-body scan is required to confirm or exclude this syndrome. Even though the surgical treatment for asymptomatic patients remains debatable, surgical intervention is the only treatment that can lead to the total removal of the tumour.
背景。血管母细胞瘤被认为是一种罕见的肿瘤,在大多数情况下,位于后颅窝。在大多数病例中,脊柱血管母细胞瘤可在胸椎和颈椎水平发现,并可在三分之一的von Hippel Lindau综合征病例中发现。 材料和方法。在本文中,我们将介绍我们的临床治疗脊髓血管母细胞瘤的经验和近10年来患者的随访情况。结果。在我们的研究中,我们包括6名男性和3名女性,平均年龄为45岁,年龄在36至61岁之间。平均住院时间为17天。在9例患者中,发现了12个肿瘤。6例患者表现为颈椎血管母细胞瘤,其中2例有胸椎病变,1例在腰椎水平发现肿瘤。此外,2例患者出现多发病变。2例患者与von Hippel - Lindau综合征相关。在所有病例中,手术都是治疗方法。 讨论。尽管技术的快速发展和治疗这些病变的新选择,手术切除血管母细胞瘤仍然是金标准治疗。 结论。血管肥大瘤是一种良性肿瘤,可与von Hippel Lindau相关。需要全身扫描来确认或排除这种综合征。尽管对无症状患者的手术治疗仍有争议,但手术干预是唯一可以导致肿瘤完全切除的治疗方法。
{"title":"Surgical management of spinal cord hemangioblastoma","authors":"George Popescu, Marius C. Zaharia, Andrei Giovani, Ioana Miron, Cezar Vîjlănescu, Radu M. Gorgan","doi":"10.33962/roneuro-2022-075","DOIUrl":"https://doi.org/10.33962/roneuro-2022-075","url":null,"abstract":"Background. Hemangioblastomas are considered rare tumours that are located, in most cases, in the posterior cranial fossa. In most of cases, spinal hemangioblastomas are identified on the thoracic and cervical levels and can be associated in one-third of cases with von Hippel Lindau Syndrome.&#x0D; Material and methods. In this paper, we are presenting our clinic`s experience with spinal hemangioblastomas and the follow-up of the patients in the last 10 years.&#x0D; Results. In our study, we included six men and three women with a mean age of 45 years, ranging between 36 to 61 years. The mean hospitalization days was 17 days. Among nine patients, there were identified 12 tumors. Six patients presented cervical spine hemangioblastomas, two of them had thoracic spine lesions and in one case, the tumour was identified at the lumbar level. Furthermore, two patients presented multiple lesions. Two patients had been associated with von Hippel Lindau Syndrome. In all cases, surgery was the therapeutic approach.&#x0D; Discussions. Despite the rapid advance of technology and the new alternatives for the treatment of these lesions, surgical resection of hemangioblastomas remains the gold standard treatment.&#x0D; Conclusions. Hemangiolbastomas are benign tumours that can be associated with von Hippel Lindau. A whole-body scan is required to confirm or exclude this syndrome. Even though the surgical treatment for asymptomatic patients remains debatable, surgical intervention is the only treatment that can lead to the total removal of the tumour.","PeriodicalId":30188,"journal":{"name":"Romanian Neurosurgery","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135405114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Romanian Neurosurgery
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