Bo Li, Yimeng Xu, R. Shi, Yimin Hu, Siying Liu, Ze-Xu Gu
Objective: The objective of this study was to detective the accuracy of model superimposition and automatic analysis for upper and lower dentition width in Invisalign Progress Assessment during the process of clear aligners. Methods 19 cases were included in this study. Pre-treatment dental cast(T0) and post-treatment dental cast after staged treatment(T1) were available for three-dimensional model superimposition. Subsequently, movements of maxillary teeth in horizontal plane (cross section) after staged treatment, width of upper and lower dentition were measured by three-dimensional model superimposition in real world and Invisalign Progress Assessment separately. Consequently, the data collected from these two methods was compared. Results In Invisalign Progress Assessment, movements of maxillary teeth in horizontal plane after staged treatment was 2.31（1.59,3.22 ） (median (upper quartile, lower quartile)) millimeter (mm), while in three-dimensional model superimposition, the result was 1.79（1.21,3.03）mm. The difference between two groups is significant(P＜0.05). Intercanine width upper, intermolar width upper, intercanine width lower, and intermolar width lower were 36.55±2.76mm, 56.98±2.62mm, 28.16±1.85mm, 53.21±2.72mm separately in Invisalign Progress Assessment and were 36.48±2.78mm, 56.89±2.58mm, 28.05±1.85mm, 53.16±2.64mm separately in three-dimensional model analysis, which were no significant difference among these groups (P＞0.05). Conclusions The data from Invisalign Progress Assessment was not in parallel with what achieved from model superimposition with palate as reference completely. The accuracy of model superimposition in Invisalign Progress Assessment needs further investigation, whereas the accuracy of model analysis in Invisalign Progress Assessment was accurate. Thereby, results from Invisalign Progress Assessment should be interpreted with caution by the orthodontist in clinic.
{"title":"Accuracy of Invisalign Progress Assessment with Clear Aligners: A Retrospective Study","authors":"Bo Li, Yimeng Xu, R. Shi, Yimin Hu, Siying Liu, Ze-Xu Gu","doi":"10.33140/jnh.07.04.12","DOIUrl":"https://doi.org/10.33140/jnh.07.04.12","url":null,"abstract":"Objective: The objective of this study was to detective the accuracy of model superimposition and automatic analysis for upper and lower dentition width in Invisalign Progress Assessment during the process of clear aligners. Methods 19 cases were included in this study. Pre-treatment dental cast(T0) and post-treatment dental cast after staged treatment(T1) were available for three-dimensional model superimposition. Subsequently, movements of maxillary teeth in horizontal plane (cross section) after staged treatment, width of upper and lower dentition were measured by three-dimensional model superimposition in real world and Invisalign Progress Assessment separately. Consequently, the data collected from these two methods was compared. Results In Invisalign Progress Assessment, movements of maxillary teeth in horizontal plane after staged treatment was 2.31（1.59,3.22 ） (median (upper quartile, lower quartile)) millimeter (mm), while in three-dimensional model superimposition, the result was 1.79（1.21,3.03）mm. The difference between two groups is significant(P＜0.05). Intercanine width upper, intermolar width upper, intercanine width lower, and intermolar width lower were 36.55±2.76mm, 56.98±2.62mm, 28.16±1.85mm, 53.21±2.72mm separately in Invisalign Progress Assessment and were 36.48±2.78mm, 56.89±2.58mm, 28.05±1.85mm, 53.16±2.64mm separately in three-dimensional model analysis, which were no significant difference among these groups (P＞0.05). Conclusions The data from Invisalign Progress Assessment was not in parallel with what achieved from model superimposition with palate as reference completely. The accuracy of model superimposition in Invisalign Progress Assessment needs further investigation, whereas the accuracy of model analysis in Invisalign Progress Assessment was accurate. Thereby, results from Invisalign Progress Assessment should be interpreted with caution by the orthodontist in clinic.","PeriodicalId":302843,"journal":{"name":"Journal of Nursing & Healthcare","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124878119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zygote contains a dna as a architecture and form cells of ectoderm ,mesoderm and endoderm DNA contains a gene and act as a architecture for cell It act as a digital clock for the cell division 1 DNA base pair supplies energy to the cell for division as when the cell divides before cytoplasmic division chromosome divides and during chromosome division a huge amount of energy is released 2 this energy is supplied for division of organelle and accurate amount of energy is released by DNA for cell to divide it is during S phase 3 During meiotic when chromosome pair up then energy is released .
{"title":"How Do Cells Determine What Size to Grow Before Divison","authors":"","doi":"10.33140/jnh.07.04.06","DOIUrl":"https://doi.org/10.33140/jnh.07.04.06","url":null,"abstract":"Zygote contains a dna as a architecture and form cells of ectoderm ,mesoderm and endoderm DNA contains a gene and act as a architecture for cell It act as a digital clock for the cell division 1 DNA base pair supplies energy to the cell for division as when the cell divides before cytoplasmic division chromosome divides and during chromosome division a huge amount of energy is released 2 this energy is supplied for division of organelle and accurate amount of energy is released by DNA for cell to divide it is during S phase 3 During meiotic when chromosome pair up then energy is released .","PeriodicalId":302843,"journal":{"name":"Journal of Nursing & Healthcare","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114626895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Primary neuroendocrine breast cancer (NEBC) is a rare entity accounting for <0.1% of all breast carcinomas and <1% of all neuroendocrine tumours. In most cases, treatment strategies in NEBC are empirical in absence of prospective trial data on NEBC cohorts. Herein, we present two case reports diagnosed with anaplastic large and small cell NEBC. After initial therapies analogue to those of breast cancer (BC) or neuroendocrine cancers (NEC) had failed, comprehensive tumour profiling was applied, leading to individualized treatment options for both patients. Due to targetable mutations and important co-alterations, the PIK3-mTOR pathway was highlighted from different aspects in both patients. The epicrisis of the two patients exemplifies how to manage the challenge of rare and difficult to treat cancers and how new diagnostic tools contribute to medical management.
{"title":"Personalized Therapy based on Several Parameters of Comprehensive Tumour Profiling: a Challenge in NEBC","authors":"","doi":"10.33140/jnh.07.04.13","DOIUrl":"https://doi.org/10.33140/jnh.07.04.13","url":null,"abstract":"Primary neuroendocrine breast cancer (NEBC) is a rare entity accounting for <0.1% of all breast carcinomas and <1% of all neuroendocrine tumours. In most cases, treatment strategies in NEBC are empirical in absence of prospective trial data on NEBC cohorts. Herein, we present two case reports diagnosed with anaplastic large and small cell NEBC. After initial therapies analogue to those of breast cancer (BC) or neuroendocrine cancers (NEC) had failed, comprehensive tumour profiling was applied, leading to individualized treatment options for both patients. Due to targetable mutations and important co-alterations, the PIK3-mTOR pathway was highlighted from different aspects in both patients. The epicrisis of the two patients exemplifies how to manage the challenge of rare and difficult to treat cancers and how new diagnostic tools contribute to medical management.","PeriodicalId":302843,"journal":{"name":"Journal of Nursing & Healthcare","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124359476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In a 76-bed acute care hospital offering inpatient and outpatient services, a 31-bed emergency department, diagnostic imaging and cardiac catheterization, we have established a commitment of zero harm through executive leadership support, strategic initiatives, and continuous quality improvement. An opportunity was identified in 2021 to reduce the amount of Hospital Acquired Infections (HAI). In 2021 the hospital had 11 HAIs.
{"title":"Quality Improvement: Achieving Zero HAIs for over 365 Days","authors":"Harry Walk","doi":"10.33140/jnh.07.03.09","DOIUrl":"https://doi.org/10.33140/jnh.07.03.09","url":null,"abstract":"In a 76-bed acute care hospital offering inpatient and outpatient services, a 31-bed emergency department, diagnostic imaging and cardiac catheterization, we have established a commitment of zero harm through executive leadership support, strategic initiatives, and continuous quality improvement. An opportunity was identified in 2021 to reduce the amount of Hospital Acquired Infections (HAI). In 2021 the hospital had 11 HAIs.","PeriodicalId":302843,"journal":{"name":"Journal of Nursing & Healthcare","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129994116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background A woman's nutritional and physical health at conception and during her pregnancy is crucial factors in defining both her own and her unborn child's health and well-being at this crucial time in her life. Therefore, the objective of the study was to investigate the effect of Behavior Change and Communication (BCC) through the women development Army on optimal nutrition and health practices of pregnant women. Methods In the Ambo district, 770 pregnant women participated in a two-arm parallel cluster randomized controlled community trial with baseline and end-line measures (385 in control and 385 in intervention groups). Endpoint data from 372 intervention and 372 control groups were gathered, respectively. In the intervention group, health development armies delivered the BCC's main message. The intervention began in July 2018, and end point data were collected from pregnant women (n = 744) in October, 2018. The control group received the typical care provided by the healthcare system during an ANC visit. Descriptive statistics, chi-square test, bivariable and lastly multivariable binary logistic regressions analysis was used to control confounders. Statistical analyses were conducted on intention-to-treat (ITT) basis and p value <0.05 was used to declare statistical significance. Result The overall optimal nutrition and health practice were higher in the intervention group than in the control group (62.6% vs. 39.0%, P<0.001). Pregnant women who received intervention had two times higher odds of optimal nutrition and health practices compared to pregnant women who were in the control group (AOR = 2.051, 95%CI: 1.318-3.192). In a multivariable binary logistic regression analysis (p<0.05), being in the intervention group, educational status, estimated time to reach the health institution, and knowledge about nutrition and health were found to be significantly associated with optimal nutrition and health practices. Conclusions Behavior change communication (BCC) through the women's development army is effective in improving optimal nutrition and health practices of pregnant women. Therefore, to improve the optimal nutrition and health practices of pregnant women, BCC through the health development army is recommended.
{"title":"The Effect of Behavior Change Communication via the Health Development Army on Pregnant Women's Nutrition and Health Practices in Ambo District, Ethiopia: A Cluster Randomized Controlled Community Trial","authors":"Gebremichael Ma","doi":"10.33140/jnh.07.04.01","DOIUrl":"https://doi.org/10.33140/jnh.07.04.01","url":null,"abstract":"Background A woman's nutritional and physical health at conception and during her pregnancy is crucial factors in defining both her own and her unborn child's health and well-being at this crucial time in her life. Therefore, the objective of the study was to investigate the effect of Behavior Change and Communication (BCC) through the women development Army on optimal nutrition and health practices of pregnant women. Methods In the Ambo district, 770 pregnant women participated in a two-arm parallel cluster randomized controlled community trial with baseline and end-line measures (385 in control and 385 in intervention groups). Endpoint data from 372 intervention and 372 control groups were gathered, respectively. In the intervention group, health development armies delivered the BCC's main message. The intervention began in July 2018, and end point data were collected from pregnant women (n = 744) in October, 2018. The control group received the typical care provided by the healthcare system during an ANC visit. Descriptive statistics, chi-square test, bivariable and lastly multivariable binary logistic regressions analysis was used to control confounders. Statistical analyses were conducted on intention-to-treat (ITT) basis and p value <0.05 was used to declare statistical significance. Result The overall optimal nutrition and health practice were higher in the intervention group than in the control group (62.6% vs. 39.0%, P<0.001). Pregnant women who received intervention had two times higher odds of optimal nutrition and health practices compared to pregnant women who were in the control group (AOR = 2.051, 95%CI: 1.318-3.192). In a multivariable binary logistic regression analysis (p<0.05), being in the intervention group, educational status, estimated time to reach the health institution, and knowledge about nutrition and health were found to be significantly associated with optimal nutrition and health practices. Conclusions Behavior change communication (BCC) through the women's development army is effective in improving optimal nutrition and health practices of pregnant women. Therefore, to improve the optimal nutrition and health practices of pregnant women, BCC through the health development army is recommended.","PeriodicalId":302843,"journal":{"name":"Journal of Nursing & Healthcare","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131301170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evidence-based practice in nursing assures patient safety and improved patient outcomes as they transition their role in nursing, master’s-prepared nurses are expected utilize evidence to integrate theory and improve clinical practice, as well as continue to advance knowledge [1]. Within the graduate nursing curriculum, a final evidence-based practice project (EBPP) can provide students with the opportunity to gain experience and develop the needed leadership skill set to promote the evidence that leads to best practice within multiple settings. The knowledge and experiences gained also support the emergence of transformational leadership. The following article will examine the EBPP specifics at one academic institution, and its correlation with transformational leadership.
{"title":"The Role of the Evidence-Based Practice Project in Building Transformational Leadership Skills in Nursing","authors":"","doi":"10.33140/jnh.07.03.01","DOIUrl":"https://doi.org/10.33140/jnh.07.03.01","url":null,"abstract":"Evidence-based practice in nursing assures patient safety and improved patient outcomes as they transition their role in nursing, master’s-prepared nurses are expected utilize evidence to integrate theory and improve clinical practice, as well as continue to advance knowledge [1]. Within the graduate nursing curriculum, a final evidence-based practice project (EBPP) can provide students with the opportunity to gain experience and develop the needed leadership skill set to promote the evidence that leads to best practice within multiple settings. The knowledge and experiences gained also support the emergence of transformational leadership. The following article will examine the EBPP specifics at one academic institution, and its correlation with transformational leadership.","PeriodicalId":302843,"journal":{"name":"Journal of Nursing & Healthcare","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126229348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hydatidosis is a neglected cyclozoonotic disease affecting both humans and livestock populatio. The objective of the paper was to review the hydatidosis disease. The overall prevalence of the hydatidosi was reported in the country: 4.9%, 6.8%, 8.02%, 9.7%, 11.3%,11.78%, 16.79%, 17.4%, 27.64%, 35.15% and 49.5% respectively. The most common source of infection: contamination of water and feed by dogs feces. The main Reservoir, risk factors for distribution of the disease are forage, water, and host, pathogenic risk factors respectively. All domestic animal are the people at risk for thedisease. The major clinical forms of hydatidosis are rup-ture of cysts, particularly into serosal cavities, may cause acute and sometimes fatal anaphylactic reaction. Effective control and prevention measures should be introduced to minimize the risk of public health hazard and economic losses can be controlled through preventive mea¬sures that break the life cycle between the definitive and inter¬mediate hosts. They must be improving hygienic management for animals and health educations for peoples about the disease for reduceinfection.
{"title":"Epidemiology of Hydatidosis in Ethiopia","authors":"","doi":"10.33140/jnh.07.03.03","DOIUrl":"https://doi.org/10.33140/jnh.07.03.03","url":null,"abstract":"Hydatidosis is a neglected cyclozoonotic disease affecting both humans and livestock populatio. The objective of the paper was to review the hydatidosis disease. The overall prevalence of the hydatidosi was reported in the country: 4.9%, 6.8%, 8.02%, 9.7%, 11.3%,11.78%, 16.79%, 17.4%, 27.64%, 35.15% and 49.5% respectively. The most common source of infection: contamination of water and feed by dogs feces. The main Reservoir, risk factors for distribution of the disease are forage, water, and host, pathogenic risk factors respectively. All domestic animal are the people at risk for thedisease. The major clinical forms of hydatidosis are rup-ture of cysts, particularly into serosal cavities, may cause acute and sometimes fatal anaphylactic reaction. Effective control and prevention measures should be introduced to minimize the risk of public health hazard and economic losses can be controlled through preventive mea¬sures that break the life cycle between the definitive and inter¬mediate hosts. They must be improving hygienic management for animals and health educations for peoples about the disease for reduceinfection.","PeriodicalId":302843,"journal":{"name":"Journal of Nursing & Healthcare","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132993587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Seattle Veterinary Outreach, a nonprofit organization providing free and sliding-scale veterinary services to those experiencing homelessness and low-income residents of the Seattle Washington Puget Sound area, began operations in 2019. A key premise of the organization is that offering veterinary services creates a trusting relationship with pet owners that fosters guiding human clients toward obtaining services for their own health and well-being [1]. Pet owners face significant barriers to obtaining care for themselves due to the lack of pet-friendly housing, shelter, and medical care clinics [2]. Methods: To support this vision, SVO partners with human care service providers to co-locate, allowing for pet-friendly access to needed services. Up until now, the decision about partners has been made based on immediate needs, circumstances, and availability. The purpose of this study was to develop a data-driven process that would assist in identifying the type of human care services needed, create a ranking system to assist in securing these services and identify partners that can co-locate with SVO mobile clinics to address human care needs. Relying on data collected by SVO staff and volunteers and incorporating attributes of potential partners into the discussion, a data-driven process for partner outreach was created. Results: A new process was created that is currently in use and will be incorporated into staff responsibilities. Conclusion: The new process offers an opportunity to ensure that the needs of pet owners are being best served.
{"title":"Creating Evidence Driven Practices to Enhance Human Care Services for Unhoused and Low-Income Pet Owners","authors":"Audrey L. Covner, Brianna Sherman","doi":"10.33140/jnh.07.03.06","DOIUrl":"https://doi.org/10.33140/jnh.07.03.06","url":null,"abstract":"Background: Seattle Veterinary Outreach, a nonprofit organization providing free and sliding-scale veterinary services to those experiencing homelessness and low-income residents of the Seattle Washington Puget Sound area, began operations in 2019. A key premise of the organization is that offering veterinary services creates a trusting relationship with pet owners that fosters guiding human clients toward obtaining services for their own health and well-being [1]. Pet owners face significant barriers to obtaining care for themselves due to the lack of pet-friendly housing, shelter, and medical care clinics [2]. Methods: To support this vision, SVO partners with human care service providers to co-locate, allowing for pet-friendly access to needed services. Up until now, the decision about partners has been made based on immediate needs, circumstances, and availability. The purpose of this study was to develop a data-driven process that would assist in identifying the type of human care services needed, create a ranking system to assist in securing these services and identify partners that can co-locate with SVO mobile clinics to address human care needs. Relying on data collected by SVO staff and volunteers and incorporating attributes of potential partners into the discussion, a data-driven process for partner outreach was created. Results: A new process was created that is currently in use and will be incorporated into staff responsibilities. Conclusion: The new process offers an opportunity to ensure that the needs of pet owners are being best served.","PeriodicalId":302843,"journal":{"name":"Journal of Nursing & Healthcare","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123065637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Old age is an old age characterized by physiological changes and a specific social role. Gerontology is a scientific discipline that studies age as a chronological age with specifics in the social role of the individual. Gerontological nursing is a dynamic process between the elderly and the nurse conducted by nurses at all levels of health care. Nursing care is divided into care in hospital institutions, care in one’s own home and care in permanent residence institutions. Nursing care for the elderly is mostly provided at the primary level of health care
{"title":"Gerontological Nursing is a Dynamic Procedure","authors":"","doi":"10.33140/jnh.07.03.02","DOIUrl":"https://doi.org/10.33140/jnh.07.03.02","url":null,"abstract":"Old age is an old age characterized by physiological changes and a specific social role. Gerontology is a scientific discipline that studies age as a chronological age with specifics in the social role of the individual. Gerontological nursing is a dynamic process between the elderly and the nurse conducted by nurses at all levels of health care. Nursing care is divided into care in hospital institutions, care in one’s own home and care in permanent residence institutions. Nursing care for the elderly is mostly provided at the primary level of health care","PeriodicalId":302843,"journal":{"name":"Journal of Nursing & Healthcare","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132556519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background Noval oncological therapies as chemotherapeutic drugs, immunotherapeutic, olecular target therapy and radiotherapies have improve cancer survivorship by potentially life-saving. These noval anti-neoplastic therapies have a significant adverse outcomes, particularly cardiotoxicity which prevent patients from complete receiving cancer treatment and so increase morbidity and mortality rate. Cardiovascular disease is the leading cause of noncancer deaths. Cardiovascular disease and cancer consider as the first and second most common cause of the burden of disease and death. Nowadays they are highly recognized and its drawback prevention remains challenging in cancer survivorship . Development of cadiovascular affection is associated with multiple modifiable risk factors including obesity, hypertension , diabetes, alcohol consumption, smoking, age, chronic kidney disease. Pre-assessment of those patients most likely to be given the cardioprotective therapy to improve cardiac outcomes in patients with preexisting heart disease . Objective to thorough the light on the importance of assessment of cardiac status before beginning in anti-cancer therapies to avoid cardiotoxicity . Methods a systematic literature review depends on collecting data from an evidence-based studies.Searches were made of forty electronic databases: the Cochrane Oral Health Group’s Trials Register, The Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, PsycINFO, Scopus and Web of science, MEDLINE(PubMed). Results Systematic reviews have demonstrated correlation between anti cancer therapies and cardiovascular diseases (cardiotoxicity) especially with patients have a pre-existing risk factors . Conclusions Close collaboration among oncologists, hematologist , cardiologists, and primary care physicians to work together in a multidisciplinary setting for effective management of patients.
新的肿瘤治疗方法，如化疗药物、免疫治疗、分子靶向治疗和放射治疗，通过潜在的挽救生命来提高癌症的生存率。这些新的抗肿瘤疗法有明显的不良后果，特别是心脏毒性，使患者无法完全接受癌症治疗，从而增加发病率和死亡率。心血管疾病是非癌症死亡的主要原因。心血管疾病和癌症被认为是造成疾病负担和死亡的第一和第二大常见原因。如今，它们得到了高度的认可，但其缺点在癌症幸存者的预防中仍然具有挑战性。心血管疾病的发生与多种可改变的危险因素有关，包括肥胖、高血压、糖尿病、饮酒、吸烟、年龄、慢性肾脏疾病。预先评估那些最有可能给予心脏保护治疗以改善已有心脏病患者心脏预后的患者。目的探讨在抗癌治疗开始前评估心脏状态对避免心脏毒性的重要性。方法系统的文献综述依赖于收集基于证据的研究数据。检索了40个电子数据库:Cochrane口腔健康组试验注册，Cochrane中央对照试验注册(Central)， EMBASE, PsycINFO, Scopus和Web of science, MEDLINE(PubMed)。结果系统评价表明，抗癌治疗与心血管疾病(心脏毒性)之间存在相关性，特别是与患者已有危险因素有关。结论肿瘤学家、血液学家、心脏病学家和初级保健医生之间的密切合作，在多学科环境中共同工作，有效地管理患者。
{"title":"Novel Anti-Cancer Therapies and Cardiac Outcomes :Systematic Reviews","authors":"","doi":"10.33140/jnh.07.03.07","DOIUrl":"https://doi.org/10.33140/jnh.07.03.07","url":null,"abstract":"Background Noval oncological therapies as chemotherapeutic drugs, immunotherapeutic, olecular target therapy and radiotherapies have improve cancer survivorship by potentially life-saving. These noval anti-neoplastic therapies have a significant adverse outcomes, particularly cardiotoxicity which prevent patients from complete receiving cancer treatment and so increase morbidity and mortality rate. Cardiovascular disease is the leading cause of noncancer deaths. Cardiovascular disease and cancer consider as the first and second most common cause of the burden of disease and death. Nowadays they are highly recognized and its drawback prevention remains challenging in cancer survivorship . Development of cadiovascular affection is associated with multiple modifiable risk factors including obesity, hypertension , diabetes, alcohol consumption, smoking, age, chronic kidney disease. Pre-assessment of those patients most likely to be given the cardioprotective therapy to improve cardiac outcomes in patients with preexisting heart disease . Objective to thorough the light on the importance of assessment of cardiac status before beginning in anti-cancer therapies to avoid cardiotoxicity . Methods a systematic literature review depends on collecting data from an evidence-based studies.Searches were made of forty electronic databases: the Cochrane Oral Health Group’s Trials Register, The Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, PsycINFO, Scopus and Web of science, MEDLINE(PubMed). Results Systematic reviews have demonstrated correlation between anti cancer therapies and cardiovascular diseases (cardiotoxicity) especially with patients have a pre-existing risk factors . Conclusions Close collaboration among oncologists, hematologist , cardiologists, and primary care physicians to work together in a multidisciplinary setting for effective management of patients.","PeriodicalId":302843,"journal":{"name":"Journal of Nursing & Healthcare","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122379043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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