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Management of Ureteric Small Bowel Fistula: A Case Report and Review of the Current Literature. 输尿管小肠瘘的治疗:1例报告及文献复习。
Pub Date : 2025-08-08 eCollection Date: 2025-01-01 DOI: 10.1155/criu/7232300
Panagiota Fallon, Melissa Matthews, Abhisekh Chatterjee, Dimitrios Sapountzis, Nikolaos Chatzikrachtis, Katie McComb, Samuel Bishara, Ivo Donkov, Konstantinos Charitopoulos, Panagiotis Nikolinakos

Background: Ureteric small bowel fistulas are rare entities, with limited reports in the literature. These pathological connections between the ureter and small bowel can lead to recurrent upper urinary tract infections and pose significant diagnostic and therapeutic challenges. The primary cause of ureteric small bowel fistula formation is iatrogenic intervention, such as percutaneous nephrolithotomy (PCNL) or abdominal surgery involving tissue resection. However, they can also arise spontaneously due to local chronic inflammation and infection. Given their rarity, there is no standardised management pathway, and the treatment approach should be individualised. Case Presentation: We present the case of a 57-year-old man presenting with a history of extensive locally advanced distal sigmoid carcinoma, managed with Hartmann's procedure with end colostomy followed by adjuvant radiotherapy and chemotherapy. He later developed a mid-ureteric small bowel fistula, presenting with urosepsis, a high-output stoma, deteriorating renal function and severe metabolic acidosis. Conservative management with regular ureteric stent exchanges every 3-4 months has successfully preserved renal function and improved his quality of life. Surgical closure was not pursued due to high operative risk, and repeat imaging has shown no evidence of persisting fistula, suggesting possible spontaneous closure. Conclusion: The treatment options for this ureteric small bowel fistula were limited. A lifelong nephrostomy was deemed unsuitable due to incompatibility with the patient's profession, and surgical intervention was associated with significant complexity due to the patient's history of malignancy and radiotherapy-related tissue changes. Therefore, a conservative strategy involving serial ureteric stent exchanges was pursued. Early recognition and individualised treatment of ureteric-enteric fistulas are essential, as timely intervention can significantly enhance prognosis and quality of life.

背景:输尿管小肠管是一种罕见的疾病,文献报道有限。输尿管和小肠之间的这些病理连接可导致复发性上尿路感染,并对诊断和治疗构成重大挑战。输尿管小肠管形成的主要原因是医源性干预,如经皮肾镜取石术(PCNL)或涉及组织切除的腹部手术。然而,它们也可能由于局部慢性炎症和感染而自发产生。鉴于其罕见性,目前尚无标准化的管理途径,治疗方法应因地制宜。病例介绍:我们报告了一个57岁的男性病例,他有广泛的局部晚期乙状结肠远端癌的病史,用Hartmann的手术和末端结肠造口术后进行辅助放疗和化疗。他后来发展为输尿管中段小肠瘘,表现为尿脓毒症、高输出口、肾功能恶化和严重的代谢性酸中毒。每3-4个月定期更换输尿管支架的保守治疗成功地保留了肾功能并改善了他的生活质量。由于手术风险高,没有进行手术关闭,重复成像显示没有持续瘘管的证据,提示可能是自发关闭。结论:输尿管小肠瘘的治疗方法有限。由于与患者的职业不相容,终身肾造口术被认为是不合适的,并且由于患者的恶性肿瘤病史和放疗相关的组织改变,手术干预具有显著的复杂性。因此,保守策略包括输尿管支架置换。输尿管-肠瘘的早期识别和个体化治疗至关重要,及时干预可显著改善预后和生活质量。
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引用次数: 0
A Case of Malignant Priapism Secondary to Muscle Invasive Bladder Cancer and Review of Palliative Management. 肌性浸润性膀胱癌继发恶性阴茎勃起障碍1例及姑息治疗回顾。
Pub Date : 2025-07-18 eCollection Date: 2025-01-01 DOI: 10.1155/criu/2340917
David Fenton, Simon Han, Adrianna Lee, Alexandra Hernandez Perez, Kristina Gam, Jung Woo Kwon, Piyush Agarwal, Omer Raheem

Malignant priapism secondary to a genitourinary malignancy is a rare and late-stage oncological finding. A 72-year-old man with a past medical history of muscle-invasive bladder cancer treated with trimodal therapy presented with altered mental status, white discharge from his Foley catheter, and bilateral corporal rigidity. Initial pelvic magnetic resonance imaging demonstrated engorgement of the corporal bodies without obvious tumor invasion. The patient eventually underwent penile exploration and bilateral decompression, and a biopsy revealed high-grade urothelial carcinoma invading the corporal tissues. Despite current guidelines for priapism, we present a three-tiered approach to the management of malignant priapism.

恶性阴茎勃起症继发于泌尿生殖系统恶性肿瘤是一种罕见的晚期肿瘤发现。一名72岁男性,既往有肌肉浸润性膀胱癌病史,曾接受三模式治疗,表现为精神状态改变,Foley导尿管排出白色分泌物,双侧身体僵硬。最初的盆腔磁共振成像显示下体肿胀,无明显肿瘤侵袭。患者最终接受了阴茎探查和双侧减压,活检显示高度尿路上皮癌侵犯了下体组织。尽管目前的指导方针阴茎勃起,我们提出了一个三层的方法来管理恶性阴茎勃起。
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引用次数: 0
Knotting of a Urinary Catheter and Ureteric Stent: A Unique Complication and Management Solution. 导尿管和输尿管支架打结:一种独特的并发症和处理方法。
Pub Date : 2025-07-10 eCollection Date: 2025-01-01 DOI: 10.1155/criu/5559138
H Logan, K Lockhart, P Chong

Objective: Spontaneous intravesical knotting is a highly infrequent complication of urinary catheters. We present a novel endoscopic treatment approach to managing a spontaneously knotted urinary catheter around a ureteric stent. Subject: A 79-year-old man presented to the Emergency department with confusion and acute renal failure. His background was significant for metastatic castrate-resistant prostate cancer. His associated obstructive uropathy was managed with a long-term right 7-Fr Rüsch ureteric stent, last changed 1 month prior and a long-term 18-Fr indwelling catheter. A CT intravenous pyelogram clearly demonstrated his indwelling catheter knotted around and through the distal intravesical portion of an appropriately positioned right ureteric stent. Results: Following decompression of the left kidney via percutaneous nephrostomy, attempts were made to remove the urinary catheter under fluoroscopy with a variety of wires and introducers. The patient then underwent a general anesthesia, and the knot was successfully removed piecemeal with a Mauermayer stone crusher via 25-Fr access sheath. Conclusion: Endoscopic techniques such as the use of a stone crusher may be beneficial for the removal of difficult and complex catheter knots as demonstrated in this case. Catheter knotting should always be considered if the functioning or attempted removal of the catheter is abnormal and timely referral to a urologist is made.

目的:膀胱内自发打结是一种罕见的导尿管并发症。我们提出了一种新的内窥镜治疗方法来处理输尿管支架周围自发打结的导尿管。主题:一名79岁男性因意识不清和急性肾衰竭来到急诊科。他的背景是转移性去势抵抗性前列腺癌。他的相关梗阻性尿路病变通过长期右侧7-Fr r输尿管支架治疗,最后一次更换是在1个月前,并长期18-Fr留置导尿管。CT静脉肾盂造影清楚地显示他的留置导管缠结并穿过右输尿管支架的远端膀胱部分。结果:经皮肾造口术对左肾进行减压后,在透视下尝试用各种导线和导尿管拔出尿管。患者随后接受全身麻醉,并用Mauermayer石粉碎机通过25-Fr通路鞘成功地将结部分去除。结论:内窥镜技术,如使用石粉碎机可能有利于去除困难和复杂的导管结,正如本病例所示。导管打结应始终考虑,如果功能或试图去除导管是异常的,并及时转诊到泌尿科医生。
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引用次数: 0
Erectile Dysfunction and Peyronie's Disease Following a Severe Case of COVID-19: A Case Report. 重症COVID-19后的勃起功能障碍和佩罗尼病1例报告
Pub Date : 2025-07-04 eCollection Date: 2025-01-01 DOI: 10.1155/criu/4329786
Eric Qualkenbush, Evan Gibbs, Bryce Baird, Gregory Broderick

The COVID-19 pandemic affected millions worldwide. While mainly regarded as a respiratory process, there may be both direct and indirect urologic consequences that are sparsely discussed. This case report describes a patient with a severe COVID-19 infection resulting in a kidney and liver transplant. After recovery, the patient was found to have de novo erectile dysfunction and Peyronie's disease. We suspect the systemic inflammation and vasculopathy leading to liver and renal failure also caused severe atherosclerotic erectile dysfunction. Furthermore, the prone positioning likely represents an iatrogenic etiology of Peyronie's disease. This unique case demonstrates some important considerations from a men's health perspective when caring for patients following a severe COVID-19 infection.

COVID-19大流行影响了全球数百万人。虽然主要被认为是一个呼吸过程,但可能有直接和间接的泌尿系统后果,但很少讨论。本病例报告描述了一例严重感染COVID-19导致肾和肝移植的患者。康复后,患者被发现有新发勃起功能障碍和佩罗尼病。我们怀疑导致肝肾功能衰竭的全身炎症和血管病变也导致了严重的动脉粥样硬化性勃起功能障碍。此外,俯卧位可能代表了Peyronie病的医源性病因。这个独特的病例表明,在照顾严重感染COVID-19的患者时,从男性健康的角度考虑了一些重要的问题。
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引用次数: 0
Duplex Renal Collecting System Lithiasis: A Case of a Challenging Management Technique. 双肾收集系统结石:一个具有挑战性的管理技术。
Pub Date : 2025-06-12 eCollection Date: 2025-01-01 DOI: 10.1155/criu/1543018
Ioannis Loufopoulos, Clarence Zwengunde, Soumendra Datta

Duplex renal collecting system is a relatively common congenital abnormality affecting equally both pelvicalyceal systems. Although usually it is an incidental finding, it can cause significant problems to the patients such as recurrent urinary tract infections, hydronephrosis, and lithiasis. In this study, we describe an interesting surgical management option for a patient with upper moiety hydronephrosis and lithiasis of the aberrant ureter, achieving resolution of the hydronephrosis and complete removal of the calculus. A 49-year-old female patient presented with symptoms of left colicky pain. During the initial investigation, a left-sided duplex renal collecting system with severely hydronephrotic upper pole moiety and grossly dilated tortuous ureter with distal calculus and ectopic insertion to urinary bladder was identified. On cystoscopy, the upper moiety ureteric opening was identified distally to the urethral sphincter. Under ultrasound guidance, endoscopic transvesical resection was performed distal to the stented lower moiety ureteric orifice, resulting in the identification of the stone and extraction. Short- and long-term follow-up demonstrated no recurrence of the stone and significant resolution of the hydronephrosis. In conclusion, in this case report, we describe an unusual anatomical variation of the upper moiety outflow, and we introduce a new technique of intravesical ultrasound-guided removal of an obstructive calculus.

双肾收集系统是一种相对常见的先天性畸形,同样影响两个盆腔系统。虽然它通常是偶然发现的,但它会给患者带来严重的问题,如复发性尿路感染、肾积水和结石。在这项研究中,我们描述了一种有趣的手术治疗方案,用于治疗上段肾积水和异常输尿管结石的患者,实现了肾积水的解决和结石的完全清除。一名49岁女性患者,表现为左侧绞痛。在最初的调查中,发现了左侧双肾收集系统,上极部分严重肾积水,输尿管严重扩张弯曲,远端结石和膀胱异位插入。膀胱镜检查发现输尿管上段开口位于尿道括约肌的远端。超声引导下,经膀胱内镜切除支架下段输尿管口远端,发现结石并取出。短期和长期随访均未发现结石复发,肾积水明显缓解。总之,在这个病例报告中,我们描述了一个不寻常的上部分流出的解剖变异,我们介绍了一种膀胱内超声引导下去除阻塞性结石的新技术。
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引用次数: 0
Penile Metastasis as the Presenting Symptom of Colorectal Carcinoma: A Rare Case Report. 阴茎转移为结直肠癌的主要症状:一罕见病例报告。
Pub Date : 2025-05-26 eCollection Date: 2025-01-01 DOI: 10.1155/criu/8856762
Mann Patel, Alain Kaldany, Farida Tanko, Andrew Parrott, Thomas L Jang

Background: Secondary penile cancer, despite the region's rich vascularization, is a rare phenomenon with only around 500 cases ever reported, typically of genitourinary origin and in even rarer cases, of colorectal adenocarcinoma. Unfortunately, the underlying mechanisms are not well elucidated, and prognosis remains poor with a late onset and median overall survival of 9 months for colon adenocarcinoma. Secondary penile cancer often presents alongside concurrent metastases months or years following successful treatment of the primary tumor. However, we report a case of an isolated penile metastasis as the presenting symptom of colon adenocarcinoma with no identifiable primary lesion or history of malignancy. Case Summary: A 67-year-old African-American male presented with a 1-month history of voiding symptoms, whereupon follow-up revealed a penile mass near the left base of the penis. Postoperative histopathological, immunohistochemical, and genomic analyses revealed characteristics of invasive and metastatic colorectal adenocarcinoma. Initial diagnostic testing revealed elevations in serum tumor markers CA 19-9 and carcinoembryonic antigen, while whole body PET/CT scan and colonoscopy failed to identify any tumorigenic lesions or primary colorectal malignancy. Although hypermetabolic activity was noted near the base of the penis and bilateral inguinal lymph nodes, the patient is currently on chemotherapy with a modified FOLFOX-6 regimen with active surveillance and no adverse effects. Conclusion: Here, we report a rare case of isolated penile metastasis as the first presentation of colon adenocarcinoma with no primary lesion. Regardless of origin, secondary penile cancer is a rare phenomenon with a poor prognosis. While the exact mechanism of spread is uncertain, the most probable mode of dissemination is through venous networks. There is also no standard of treatment relying on surgical, therapeutic, and palliative management. Although unclear, our unique presentation may portend a more favorable prognosis with continued treatment and observation.

背景:继发性阴茎癌,尽管该地区血管丰富,是一种罕见的现象,只有大约500例报道,通常起源于泌尿生殖系统,在更罕见的情况下,结直肠腺癌。不幸的是,潜在的机制尚未很好地阐明,预后仍然很差,结肠腺癌的发病晚,中位总生存期为9个月。继发性阴茎癌通常在原发肿瘤成功治疗数月或数年后出现并发转移。然而,我们报告一例孤立的阴茎转移作为结肠癌的主要症状,没有可识别的原发病变或恶性肿瘤史。病例总结:67岁非裔美国男性,有1个月的排尿症状,随访发现阴茎左基部附近有阴茎肿块。术后组织病理学、免疫组织化学和基因组分析显示了侵袭性和转移性结直肠癌的特征。最初的诊断测试显示血清肿瘤标志物CA 19-9和癌胚抗原升高,而全身PET/CT扫描和结肠镜检查未能发现任何致瘤性病变或原发性结直肠恶性肿瘤。虽然在阴茎底部和双侧腹股沟淋巴结附近发现了高代谢活动,但患者目前正在接受改进的FOLFOX-6方案的化疗,并进行积极监测,无不良反应。结论:在此,我们报告一例罕见的孤立性阴茎转移为结肠癌的第一个表现,没有原发病变。不论起源,继发性阴茎癌是一种罕见的现象,预后较差。虽然传播的确切机制尚不确定,但最可能的传播方式是通过静脉网络。也没有标准的治疗依赖于手术,治疗和姑息管理。虽然尚不清楚,但我们独特的表现可能预示着继续治疗和观察的预后更有利。
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引用次数: 0
Retroperitoneal Mystery: Primary Retroperitoneal Mucinous Cystic Neoplasm With Concomitant Cystic Neoplasm of the Pancreas. 腹膜后未解之谜:原发性腹膜后粘液囊性肿瘤伴发胰腺囊性肿瘤。
Pub Date : 2025-05-22 eCollection Date: 2025-01-01 DOI: 10.1155/criu/3296313
Luis Gonzalez Miranda, Jessica Qiu, Yubo Wu, Kirsten Greene

Urologists are commonly referred patients with retroperitoneal lesions and masses arising from or involving the kidney. In this case, the patient had a retroperitoneal mass identified on imaging which was initially concerning for a cystic renal neoplasm, but it was clearly distinct from all surrounding structures. Pathology found the very uncommon and unexpected diagnosis of a mucinous cystic neoplasm (MCN) with ovarian-type stroma suspected to have arisen from the pancreas. MCNs are lesions that most commonly arise in the ovaries, but less often can arise in extraovarian tissues. Of these extraovarian MCNs, primary retroperitoneal MCNs are exceedingly rare masses with some similarity to their pancreatic and ovarian counterparts. We present a case of an MCN found in the retroperitoneum and initially mistaken for a cystic renal mass, with histological markers and a concomitant pancreatic cyst that suggests possible pancreatic origin. Interestingly, no literature has described pancreatic MCNs without invasive features that have been found in the retroperitoneum without any formal tissue connection to the pancreas. The pathogenesis of retroperitoneal MCNs is still unknown, and as a result, the optimal treatment strategy is unclear.

泌尿科医生通常转诊由肾脏引起或累及肾脏的腹膜后病变和肿块的患者。在本例中,患者在影像学上发现腹膜后肿块,最初与囊性肾肿瘤有关,但与周围所有结构明显不同。病理发现非常罕见和意想不到的诊断粘液囊性肿瘤(MCN)卵巢型间质怀疑起源于胰腺。mcn是最常发生在卵巢的病变,但很少发生在卵巢外组织。在这些卵巢外mcn中,原发性腹膜后mcn极为罕见,与胰腺和卵巢mcn有一些相似之处。我们报告一例在腹膜后发现的MCN,最初被误认为是囊性肾肿块,组织学标记和伴随的胰腺囊肿提示可能的胰腺起源。有趣的是,没有文献描述在腹膜后发现的胰腺mcn没有侵袭性特征,与胰腺没有任何正式的组织连接。腹膜后MCNs的发病机制尚不清楚,因此,最佳治疗策略尚不清楚。
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引用次数: 0
Inability to Perform Retrograde Ureteroscopic Stone Treatment: A Postoperative Anatomical Change After Fleur-de-Lis Abdominoplasty. 无法进行逆行输尿管镜下结石治疗:百合腹部成形术后的解剖改变。
Pub Date : 2025-05-21 eCollection Date: 2025-01-01 DOI: 10.1155/criu/4992363
Parker L Heger, Thomas F Rashid, Lucas B Vergamini, Bristol B Whiles, Aaron Tverye, Wilson R Molina

Abdominoplasty is a frequently performed elective procedure, often indicated for patients after substantial weight loss resulting in significant redundant skin. Closing techniques and the lifting of the mons pubis during abdominoplasty have been proposed to alleviate symptoms of stress urinary incontinence by elevating and supporting the urethra. Despite these observations, the impact of abdominoplasty on pelvic anatomy and subsequent endoscopic procedures remains underexplored and underreported. We present a case where cystoscope passage as part of endoscopic laser lithotripsy for nephrolithiasis was impeded by altered anatomy in a patient with a history of Fleur-de-Lis abdominoplasty.

腹部成形术是一种常用的选择性手术,通常用于体重减轻导致皮肤明显多余的患者。在腹部成形术中,闭合技术和提升耻骨可以通过抬高和支撑尿道来缓解压力性尿失禁的症状。尽管有这些观察结果,腹部成形术对骨盆解剖和随后的内窥镜手术的影响仍然未被充分探索和报道。我们提出了一个病例,其中膀胱镜通过作为肾结石的内镜激光碎石术的一部分,被改变的解剖结构阻碍了患者的历史鸢尾花腹部成形术。
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引用次数: 0
Recurrent Urosepsis Following Stent Removal for Ureteral Stones: A Case Report. 输尿管结石支架取出后尿脓毒症复发1例报告。
Pub Date : 2025-04-23 eCollection Date: 2025-01-01 DOI: 10.1155/criu/5547651
Cesar Prugue, Parker Reber, Amanda Austin

Urosepsis, a severe infection originating from the urinary tract, can be life-threatening. We present the case of a 56-year-old female who developed urosepsis twice within 15 days, each episode occurring shortly after stent removal. Ureteroscopy with stent placement was initially performed to treat a 12-mm stone in the distal left ureter. Although the stent was removed only after imaging showed no residual stones, sepsis developed shortly after, leading to another ureteroscopy and stent placement. Before the removal of the second stent, imaging again confirmed no stones were present, yet she experienced sepsis once more following the second stent removal. Further imaging studies during hospital admission for both episodes of sepsis revealed stone fragments and hydronephrosis which were missed during office evaluations. This case highlights the need for more effective imaging techniques to detect residual stones. The decision to place a stent after ureteroscopy for ureteral stone treatment should also be carefully considered, even for low-risk patients, to reduce infection risk.

尿脓毒症是一种源自泌尿道的严重感染,可能危及生命。我们报告了一位56岁的女性患者,她在15天内两次出现尿脓毒症,每次发作都发生在支架移除后不久。输尿管镜下支架置入治疗左侧远端输尿管12毫米结石。尽管在影像学检查未发现结石残留后才取出支架,但不久后脓毒症发生,导致再次输尿管镜检查和支架置入。在第二次支架移除之前,影像学再次证实没有结石存在,但在第二次支架移除后,她再次出现败血症。两例败血症住院期间的进一步影像学检查显示结石碎片和肾积水,这在办公室评估中被遗漏。这个病例强调需要更有效的成像技术来检测残留的结石。输尿管镜下输尿管结石治疗后放置支架的决定也应仔细考虑,即使是低风险患者,以减少感染风险。
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引用次数: 0
Endoscopic Removal of Superglue From the Urethra: A Case Report and Review of the Literature. 内镜下去除尿道强力胶一例报告及文献复习。
Pub Date : 2025-04-18 eCollection Date: 2025-01-01 DOI: 10.1155/criu/2780056
Marcus Derigs, Aristeidis Zacharis, Cem Aksoy, Subhajit Mandal, Johannes Huber, Christer Groeben

Background: The self-insertion of superglue into the male urethra is an uncommon and challenging cause of urethral obstruction, with only five reported cases to date. These cases demonstrate diverse clinical presentations and treatment approaches. This report presents the sixth documented case, reviews the existing literature, and proposes a structured treatment approach for superglue-induced urethral obstruction. Case Presentation: A 51-year-old male instilled superglue into his urethra to secure a pintail comb inserted for self-stimulation. Upon forcefully removing the comb, hardened superglue fragments remained stuck in the urethra, causing urinary retention. Endoscopic extraction using rigid cystoscopy and forceps under local anesthesia successfully removed all fragments from the penile urethra and bladder. Conclusion: Early endoscopic extraction using rigid cystoscopy under local anesthesia represents a safe and effective treatment option for nonadherent superglue fragments in the urethra.

背景:男性尿道内自插入强力胶是一种罕见且具有挑战性的尿道阻塞原因,迄今为止仅报道了5例。这些病例表现出不同的临床表现和治疗方法。本文报道第6例记录病例,回顾现有文献,并提出一种结构化的治疗方法来治疗超胶粘剂引起的尿道梗阻。病例介绍:一名51岁男性在尿道内注入强力胶,以固定插入自我刺激的针尖梳。在强行取出梳子后,硬化的强力胶碎片仍然卡在尿道中,导致尿潴留。在局部麻醉下,采用刚性膀胱镜和镊子成功取出阴茎、尿道和膀胱内的所有碎片。结论:局部麻醉下采用刚性膀胱镜早期内镜下取出是治疗尿道非黏附性强力胶碎片的一种安全有效的方法。
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引用次数: 0
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Case Reports in Urology
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