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The roles of nanotechnology and internet of nano things in healthcare transformation 纳米技术和纳米物联网在医疗保健转型中的作用
Pub Date : 2017-09-01 DOI: 10.22430/22565337.720
M. Maksimovic
Healthcare, as a basic human right, did not remain immune to innovative technologies. Technological progress has significantly contributed to high-quality, on-time, acceptable and affordable healthcare. Since their appearance, nanotechnology and the Internet of Nano Things (IoNT) have continuously affected healthcare and have a tremendous influence on its transformation, contributing to the better outcome. The inclusion of nanotechnology in medicine through nanomaterials and nanodevices, known as nanomedicine, has brought numerous benefits in disease prevention, diagnosis, and treatment. Going further by connecting nanodevices to the Internet, the IoNT paradigm has been created. The inclusion of IoNT concepts in healthcare has resulted in more personalized, timely, and convenient health monitoring and treatment. Hence, nanotechnology and the IoNT hold the potential to completely revolutionize healthcare in the 21st Century, creating a system that will enable early disease detection and diagnosis followed by accurate, on-time and effective treatment with significantly reduced healthcare costs. This paper presents the roles of nanotechnology and IoNT in medicine and healthcare, and attempts to gain an insight of nanoscale solutions and approaches, highlighting benefits and discussing potential risks and concerns. Despite concerns regarding nanotoxicity, privacy and security issues, it is anticipated that nanotechnology and IoNT will show their full potential in medicine and healthcare in the years to come.
医疗保健作为一项基本人权,也未能不受创新技术的影响。技术进步极大地促进了高质量、准时、可接受和负担得起的医疗保健。自出现以来,纳米技术和纳米物联网(IoNT)不断影响着医疗保健,并对其转型产生了巨大影响,为更好的结果做出了贡献。通过纳米材料和纳米器件将纳米技术纳入医学,即纳米医学,在疾病预防、诊断和治疗方面带来了许多好处。通过将纳米设备连接到互联网,进一步创建了IoNT范例。在医疗保健中纳入IoNT概念导致了更加个性化、及时和方便的健康监测和治疗。因此,纳米技术和IoNT有可能彻底改变21世纪的医疗保健,创造一个系统,使疾病的早期检测和诊断,然后是准确、及时和有效的治疗,显著降低医疗成本。本文介绍了纳米技术和IoNT在医学和医疗保健中的作用,并试图获得纳米级解决方案和方法的洞察力,突出了好处并讨论了潜在的风险和关注。尽管人们担心纳米毒性、隐私和安全问题,但预计纳米技术和IoNT将在未来几年在医学和医疗保健领域充分发挥其潜力。
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引用次数: 21
Microfabrication of position reference patterns onto glass microscope slides for high-accurate analysis of dynamic cellular events 在玻璃显微镜载玻片上微加工位置参考图案,用于高精度分析动态细胞事件
Pub Date : 2017-05-15 DOI: 10.22430/22565337.695
J. Galeano, P. Sandoz, A. Zarzycki, L. Robert, Juan Jaramillo
Glass microscopes slides are widely used as in situ base-substrates carrying diverse micro-fabricated systems or elements. For such purposes, the micro-fabrication process consists in transferring a pre-defined design onto the substrate made of a glass microscope slide. This is known as patterning, which is a technique that can also be used in transferring specific designs that allows region of interest (ROI) recovery under the microscope. In those cases, two main challenges appear: 1) Disturbances in light transmission should remain minimum to keep the high quality of observation of the object of interest under the microscope. 2) The pattern-size should then be small enough but, however, larger than the diffraction limit to be observable satisfactorily for positioning purposes. In this article, we present the procedures involved in the microfabrication of Pseudo-Periodic Patterns (PPP) encrypting the absolute position of an extended area. Those patterns are embedded in Petri dishes in order to allow the high-accurate retrieval of absolute position and orientation. The presented microfabrication is based in a technique known as lift-off, which after parameter adjustment, allows the obtaining of PPP fulfilling the two previously mentioned requirements. The results report on PPP realized on glass microscope slides and composed by 2µm side dots made of aluminum with a thickness of 30nm.
玻璃显微镜载玻片被广泛用作承载各种微制造系统或元件的原位基底。为此,微制造工艺包括将预定义的设计转移到由玻璃显微镜载玻片制成的基板上。这被称为图案化,这是一种也可以用于转移特定设计的技术,可以在显微镜下恢复感兴趣区域(ROI)。在这些情况下,出现了两个主要挑战:1)光传输中的干扰应保持最小,以保持在显微镜下对感兴趣对象的高质量观察。2) 图案尺寸应足够小,但应大于衍射极限,以便出于定位目的而令人满意地观察到。在这篇文章中,我们介绍了伪周期图案(PPP)加密扩展区域绝对位置的微制造过程。这些模式被嵌入到培养皿中,以便能够高精度地检索绝对位置和方向。所提出的微制造基于一种称为剥离的技术,在参数调整后,可以获得满足前面提到的两个要求的PPP。PPP的结果报告在玻璃显微镜载玻片上实现,由厚度为30nm的铝制成的2µm侧点组成。
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引用次数: 0
Feature relevance estimation for vibration-based condition monitoring of an internal combustion engine 基于振动的内燃机状态监测特征相关性估计
Pub Date : 2017-05-15 DOI: 10.22430/22565337.698
J. A. Hernández-Muriel, A. Álvarez-Meza, J. Echeverry-Correa, A. Orozco-Gutierrez, M. Álvarez-López
Condition monitoring of Internal Combustion Engines (ICE) benefits cost-effective operations in the modern industrial sector. Because of this, vibration signals are commonly monitored as part of a non-invasive approach to ICE analysis. However, vibration-based ICE monitoring poses a challenge due to the properties of this kind of signals. They are highly dynamic and non-stationary, let alone the diverse sources involved in the combustion process. In this paper, we propose a feature relevance estimation strategy for vibration-based ICE analysis. Our approach is divided into three main stages: signal decomposition using an Ensemble Empirical Mode Decomposition algorithm, multi-domain parameter estimation from time and frequency representations, and a supervised feature selection based on the Relief-F technique. Accordingly, we decomposed the vibration signals by using self-adaptive analysis to represent nonlinear and non-stationary time series. Afterwards, time and frequency-based parameters were calculated to code complex and/or non-stationary dynamics. Subsequently, we computed a relevance vector index to measure the contribution of each multi-domain feature to the discrimination of different fuel blend estimation/diagnosis categories for ICE. In particular, we worked with an ICE dataset collected from fuel blends under normal and fault scenarios at different engine speeds to test our approach. Our classification results presented nearly 98% of accuracy after using a k-Nearest Neighbors machine. They reveal the way our approach identifies a relevant subset of features for ICE condition monitoring. One of the benefits is the reduced number of parameters.
内燃机(ICE)的状态监测有利于现代工业部门的成本效益操作。因此,振动信号通常作为ICE分析的非侵入性方法的一部分进行监测。然而,由于这类信号的特性,基于振动的ICE监测带来了挑战。它们是高度动态和非平稳的,更不用说燃烧过程中涉及的各种来源了。在本文中,我们提出了一种用于基于振动的ICE分析的特征相关性估计策略。我们的方法分为三个主要阶段:使用集成经验模式分解算法的信号分解,根据时间和频率表示的多域参数估计,以及基于Relief-F技术的监督特征选择。因此,我们通过自适应分析对振动信号进行分解,以表示非线性和非平稳的时间序列。然后,计算基于时间和频率的参数,以对复杂和/或非平稳动力学进行编码。随后,我们计算了一个相关向量指数,以衡量每个多域特征对ICE不同燃料混合估计/诊断类别的区分的贡献。特别是,我们使用了从不同发动机转速下的正常和故障情况下的燃料混合物中收集的ICE数据集来测试我们的方法。在使用k近邻机器后,我们的分类结果显示了近98%的准确率。它们揭示了我们的方法识别ICE状况监测相关特征子集的方式。其中一个好处是减少了参数的数量。
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引用次数: 3
Analysis of the efficiency of a virtual-optical multiplexing method, by using theta modulation 利用θ调制的虚拟光多路复用方法的效率分析
Pub Date : 2017-05-15 DOI: 10.22430/22565337.699
Javier A. Vargas Valencia
We present an efficient virtual-optical multiplexing method for compressing information contained in gray level images. The efficiency is measured using three parameters: quality factors of recovered images, memory saving percentage achieved, and number of multiplexed images in the package. Theta modulation techniques are applied, to process an N number of gray level images, by using a virtual-optical 2f architecture, from which we obtain a complex package M, to be stored as two images, amplitude and phase, in commercial formats. We apply pixel optimization and Fourier plane filtering to amplitude and phase images, respectively, storing only a percentage of the Fourier plane with a pixel dynamic range optimization. The stored package spends much less memory than individual images. The recovered images after the demultiplexing process are compared with the original ones by using correlation coefficient, obtaining high quality factors for decompressed images. We perform simulations, showing the efficiency of the proposed process, and our results are compared to the same factors reported in recent publications, making our improvements evident.
提出了一种有效的虚拟光复用方法来压缩灰度图像中的信息。使用三个参数来衡量效率:恢复图像的质量因子、实现的内存节省百分比和封装中的多路复用图像数量。通过使用虚拟光学2f架构,应用Theta调制技术来处理N个灰度图像,从中我们获得一个复杂的包M,以商业格式存储为两个图像,振幅和相位。我们分别对幅值和相位图像应用像素优化和傅立叶平面滤波,通过像素动态范围优化仅存储傅立叶平面的一部分。存储的包比单个映像占用的内存少得多。利用相关系数对解复用后的恢复图像与原始图像进行比较,得到解复用后图像的高质量因子。我们进行了模拟,显示了所提出过程的效率,并将我们的结果与最近出版物中报道的相同因素进行了比较,使我们的改进显而易见。
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引用次数: 2
Big Data: una exploración de investigaciones, tecnologías y casos de aplicación 大数据:研究、技术和应用案例的探索
Pub Date : 2017-05-02 DOI: 10.22430/22565337.685
Emilcy J. Hernández-Leal, N. Duque-Méndez, Julián Moreno-Cadavid
Big Data has become a worldwide trend and although still lacks a scientific or academic consensual concept, every day it portends greater market growth that surrounds and the associated research areas. This paper reports a systematic review of the literature on Big Data considering a state of the art about techniques and technologies associated with Big Data, which include capture, processing, analysis and data visualization. The characteristics, strengths, weaknesses and opportunities for some applications and Big Data models that include support mainly for modeling, analysis, and data mining are explored. Likewise, some of the future trends for the development of Big Data are introduced by basic aspects, scope, and importance of each one. The methodology used for exploration involves the application of two strategies, the first corresponds to a scientometric analysis and the second corresponds to a categorization of documents through a web tool to support the process of literature review. As results, a summary and conclusions about the subject are generated and possible scenarios arise for research work in the field.
大数据已经成为一种全球趋势,尽管仍然缺乏科学或学术共识的概念,但它每天都预示着围绕及其相关研究领域的市场增长。本文报告了对大数据文献的系统回顾,考虑到与大数据相关的技术和技术的最新状态,包括捕获、处理、分析和数据可视化。探讨了一些应用程序和大数据模型的特点、优势、弱点和机会,这些模型主要支持建模、分析和数据挖掘。同样,还介绍了大数据未来发展的一些趋势,包括每个趋势的基本方面、范围和重要性。用于探索的方法涉及两种策略的应用,第一种对应于科学计量分析,第二种对应于通过网络工具对文件进行分类,以支持文献综述过程。结果,产生了关于该主题的总结和结论,并为该领域的研究工作提出了可能的场景。
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引用次数: 28
Uso de la perforación dinámica como un método alternativo para determinar el comportamiento mecánico de materiales refractarios 使用动态钻井作为确定耐火材料力学行为的替代方法
Pub Date : 2017-05-02 DOI: 10.22430/22565337.694
Daniel Zuluaga-Castrillón, Juan F. Hernández-Ruiz, Fabio Vargas-Galvis, M. E. López-Gómez, Claudia C. Palacio-Espinosa
Ceramic materials hardness is usually determined by Vickers microindentation, which requires rigorous sample preparation and highly demanding analysis of traces turning this method difficult to use in industrial applications. This research is focused to correlate Vickers Hardness to drilling resistance by a hard-tipped drill-bit on alumina, alumina-zirconia-silica (AZS) and alumina-chromite refractories bricks. Alumina and AZS bricks were manufactured by electromelting process leading to obtain highly densified microstructures, while alumina-chromite bricks were manufactured by pressing and sintering which conducts to lower densification and particles cohesion within the bricks microstructure. Alumina and AZS refractories measured hardness is 1506.00 ± 99.71 HV1,5N (15.10 ± 0.90 GPa) and 1028.00 ± 95.49HV2,7N (10.30 ± 0.90 GPa) respectively, which is in contrast with the low measured hardness on alumina-chromite bricks of 54.00 ± 2.00 HV50N (0.54 ± 0.02 GPa) despite of the high hardness of alumina and chromite used as feedstock maybe due to a low cohesion between the particles. Drilling resistance results showed a well-fitted behavior regarding the measured Vickers hardness then the drilling resistance test is useful to predict the hardness of highly densified as well as of friable ceramic materials.
陶瓷材料的硬度通常由维氏微压痕测定,这需要严格的样品制备和高要求的轨迹分析,这种方法难以在工业应用中使用。本文研究了硬头钻头在氧化铝、氧化铝-氧化锆-二氧化硅(AZS)和氧化铝-铬铁矿耐火砖上维氏硬度与钻削阻力的关系。氧化铝和AZS砖采用电熔法制备,获得了致密的显微组织,而铝-铬铁矿砖采用压制烧结法制备,导致了较低的致密性和砖内颗粒的粘聚性。氧化铝和AZS耐火材料测得的硬度分别为1506.00±99.71 HV1,5N(15.10±0.90 GPa)和1028.00±95.49HV2,7N(10.30±0.90 GPa),这与氧化铝-铬铁矿砖测得的硬度54.00±2.00 HV50N(0.54±0.02 GPa)形成了对比,尽管作为原料的氧化铝和铬铁矿的硬度很高,可能是由于颗粒之间的凝聚力较低。钻削阻力测试结果与测量的维氏硬度具有良好的拟合性,因此钻削阻力测试可用于预测高密度和易碎陶瓷材料的硬度。
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引用次数: 1
Reconciliación social: tecnología para la construcción de paz 社会和解:建设和平的技术
Pub Date : 2017-05-02 DOI: 10.22430/22565337.739
M. Alzate
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引用次数: 2
Control difuso del péndulo invertido con rueda de reacción usando seguimiento de trayectoria 基于轨迹跟踪的反作用轮倒立摆模糊控制
Pub Date : 2017-05-02 DOI: 10.22430/22565337.690
Víctor D. Correa-Ramírez, Didier Giraldo Buitrago, Andrés Escobar-Mejía
espanolEn este trabajo se presenta el diseno de un controlador difuso Takagi-Sugeno (T-S), con un esquema de seguimiento de trayectoria para el sistema conocido como pendulo con rueda de reaccion. A partir del modelo de estados no lineal, se definen los puntos de operacion donde el sistema funcionara y se aplica la tecnica de linealizacion por no linealidad sectorial con el fin de implementar reguladores lineales locales. Con los modelos linealizados reducidos y con base en las caracteristicas dinamicas deseadas de lazo cerrado, se disenan los reguladores locales que, al ser combinados, usando las funciones de pertenencia del modelo difuso, generan la senal de control global que contiene dos terminos: el regulador y el seguimiento simple de la referencia.El controlador difuso propuesto logra llevar el pendulo desde su posicion de equilibrio natural a la posicion invertida de forma gradual, con oscilaciones de amplitud creciente y con minimo error de seguimiento. Cuando el pendulo alcanza la posicion deseada invertida, se usa un regulador sobre el modelo linealizado completo alrededor del punto de operacion. Los resultados de simulacion muestran el seguimiento de la trayectoria angular (del pendulo) y el desempeno del controlador ante pequenas perturbaciones. La senal de control y la velocidad angular de la rueda son presentadas con el fin de verificar que se mantienen dentro de los limites de operacion establecidos. Si bien se presenta saturacion en la senal de control, se obtiene un error de seguimiento menor a 0,22 radianes. EnglishIn this work, the design of a Takagi-Sugeno Fuzzy controller with a trajectorytracking scheme for the reaction wheel pendulum is presented. By using the nonlinear state-space model, the system’s operating points are defined, then, the sector nonlinearity method is applied to obtain a linearized model of the system in order to implement linear local regulators. Once the reduced linearized models are obtained, and based on the desired closed loop response, local regulators are designed to generate the global control signal. This signal comprises two terms: The regulator and the reference tracking term. The proposed Fuzzy controller allows the pendulum to reach the upright position from its natural state by swinging it up with minimum tracking error. Once the upright position is reached, a regulator is implemented to operate over the linearized model around the operating point (i.e., upright position). Simulation results present both, the tracking of the angular trajectory and the controller behavior during small perturbations. It is shown that the control signal and the wheel speed remain within their boundaries. Although the control signal saturates, a tracking error less than 0.22 radians is observed.
本文介绍了一种高木菅野(T-S)模糊控制器的设计,该控制器为带有反应轮的钟摆系统提供了轨迹跟踪方案。从非线性状态模型出发,定义了系统工作的工作点,并应用扇区非线性线性化技术实现了局部线性调节器。在简化线性化模型的情况下,根据闭环所需的动态特性,设计了局部调节器,通过结合模糊模型的隶属函数,产生包含两个术语的全局控制信号:调节器和简单的参考跟踪。所提出的模糊控制器成功地将钟摆从其自然平衡位置逐渐带到倒置位置,振幅振荡增加,跟踪误差最小。当钟摆到达所需的倒置位置时,在操作点周围的整个线性化模型上使用调节器。仿真结果表明,在小扰动下,该控制器可以跟踪(摆动)角轨迹并进行消隐。提交控制信号和车轮角速度,以验证它们是否保持在设定的操作限制内。虽然控制信号中存在饱和,但跟踪误差小于0.22弧度。在这项工作中,介绍了一种带有反应轮摆轨迹跟踪方案的Takagi-Sugeno模糊控制器的设计。通过使用非线性状态空间模型,定义系统的工作点,然后应用扇区非线性方法获得系统的线性化模型,以实现线性局部调节器。一旦获得简化的线性化模型,并根据所需的闭环响应,设计局部调节器以产生全局控制信号。该信号包括两个术语:监管机构和参考跟踪术语。所提出的模糊控制器通过以最小的跟踪误差摆动摇杆,使摇杆从其自然状态到达正确的位置。一旦达到UPRIGHT位置,就会执行一个调节器,在操作点(即UPRIGHT位置)周围的线性模型上运行。给出了小扰动下角轨迹跟踪和控制器行为的仿真结果。结果表明,控制信号和车轮速度仍在其边界内。虽然控制信号饱和,但观察到小于0.22弧度的跟踪误差。
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引用次数: 5
Metodología para la determinación del desplazamiento angular en transformadores trifásicos 三相变压器角位移的测定方法
Pub Date : 2017-02-21 DOI: 10.22430/22565337.580
Nicolás Muñoz-Galeano, J. M. López-Lezama, Fernando Villada-Duque
Este articulo presenta una metodologia para la determinacion del desplazamiento angular (conexiones o grupos horarios (coloquial)) en transformadores trifasicos. La metodologia propuesta sirve para determinar el desplazamiento angular si se conocen las conexiones o si se desea determinado desplazamiento angular tambien poder obtener las conexiones. Si bien la conexion de transformadores trifasicos requiere el conocimiento del desplazamiento angular, la literatura tecnica no reporta una metodologia o procedimiento riguroso explicito para determinarlas. Sin embargo, existen numerosas aplicaciones en las areas de ingenieria e investigacion que requieren el conocimiento de la conexion y el desplazamiento angular. El articulo presenta la metodologia para determinar las conexiones Yy, Yd, Dy, Dd, Zy y Zd; que incluye las aplicaciones de ingenieria mas relevantes. La metodologia propuesta se puede aplicar de forma indiferente tanto para transformadores comerciales como no comerciales o para transformadores de potencia o de distribucion.
本文介绍了一种确定三相变压器角位移(连接或时间表组(口语))的方法。如果已知连接,则建议的方法用于确定角位移,或者如果希望确定角位移,也可以获得连接。虽然连接三相变压器需要了解角位移,但技术文献没有报告确定它们的明确严格方法或程序。然而,在工程和研究领域有许多应用需要了解连接和角位移。本文介绍了确定YY、YD、DY、DD、ZY和ZD连接的方法;其中包括最相关的工程应用。所提出的方法可分别适用于商用和非商用变压器或电力或配电变压器。
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引用次数: 0
Planeamiento de la expansión integrada generación-transmisión: una revisión del estado del arte 综合发电-输电扩展规划:最新技术综述
Pub Date : 2016-07-15 DOI: 10.22430/22565337.83
Sergio D. Saldarriaga-Zuluaga, J. M. López-Lezama, Nicolás Galeano
En la ultima decada, un gran numero de trabajos de investigacion han abordado el problema de la expansion de los sistemas de potencia, coordinando en un solo problema de optimizacion el planeamiento de expansion de la generacion (GEP, Generation Expansion Planning) y el planeamiento de expansion de la transmision (TEP, Transmission Expansion Planning). El GEP normalmente se lleva a cabo sin tener en cuenta las restricciones de red y desde una perspectiva energetica. Por otro lado, el TEP busca encontrar los refuerzos en la red, que atiendan una demanda futura de forma economica y confiable. La integracion de estos problemas ha sido abordada utilizando diferentes metodos, modelos y funciones objetivo. En este articulo se presenta una revision bibliografica del problema del planeamiento integrado GEP-TEP desde diferentes puntos de vista como su modelado, metodos de solucion, consideraciones de confiabilidad, entre otros. En la literatura especializada se encuentran articulos de revision que caracterizan de forma independiente los problemas GEP y TEP. Sin embargo, no se encuentran revisiones que aborden problema GEP-TEP integrado. Surge entonces la necesidad de caracterizar los aspectos del planeamiento de la expansion integrada de los sistemas de potencia, con el proposito de proporcionar herramientas de consulta para los investigadores en este campo.
在过去的十年中,一个伟大的演出安排的一些调查已经解决了这一问题的工作动力系统,单一optimizacion规划问题协调安排计划,一代一代安排Planning)的安排和规划,观念,传输安排Planning)。GEP通常不考虑电网限制,从能源的角度进行。另一方面,TEP寻求在网络中找到加强,以经济和可靠的方式满足未来的需求。利用不同的方法、模型和目标函数对这些问题进行了集成。本文从建模、求解方法、可靠性考虑等不同角度对综合规划GEP-TEP问题进行了文献综述。在专业文献中,可以找到独立描述GEP和TEP问题的综述文章。目前还没有针对综合GEP-TEP问题的综述。因此,有必要描述电力系统综合扩展规划的各个方面,以便为该领域的研究人员提供咨询工具。
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引用次数: 1
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