首页 > 最新文献

International Journal of Integrated Health Sciences最新文献

英文 中文
Paradoxical Hemiparesis from Cerebellopontine Angle Tumor: A Case Report 桥小脑角肿瘤引起的矛盾性偏瘫1例
Pub Date : 2023-09-30 DOI: 10.15850/ijihs.v11n2.2947
Maula Nuruddin Gaharu, James Gunawan
Objective: To report a vestibular schwannoma in the cerebellopontine angle presenting with paradoxical hemiparesis with the Kernohan-Woltman Notch Phenomenon (KWNP).Methods: A 31-year-old female presented to the neurology clinic at Bhayangkara Hospital TK. I R. Said Sukanto, Indonesia, on 29 November 2021 with loss of balance, hearing, vision, and weakness in her left arm and leg. On physical examination, the patient had reduced left arm and leg muscle strengths against resistance (MRC grade 4), face deviation to the left, abnormal finger-to-nose test, dysdiadochokinesia, and inability to perform tandem gait. She was admitted for a brain MRI but did not return to the hospital for re-evaluation and surgery. Results: The brain MRI showed a mass on the left side of the cerebellum with a size of 4.44x3.93x4.93 cm, suggesting vestibular schwannoma. The mass also caused the obliteration of the ventricle, causing hydrocephalus.Conclusion:KWNP is an unusual finding resulting in a paradoxical hemiparesis, a false-localizing neurologic sign. Physicians should recognize KWNP in patients with hemiparesis, especially in space-occupying lesions. Imaging studies can help localize the lesion to minimize misdiagnosis and optimize patient treatment.
目的:报道一个前庭神经鞘瘤在桥小脑角表现为反常偏瘫并伴有Kernohan-Woltman缺口现象(KWNP)。方法:一名31岁女性在Bhayangkara医院TK神经内科就诊。I R. Said Sukanto,印度尼西亚,2021年11月29日,失去平衡、听力、视力,左臂和左腿无力。体格检查显示,患者左臂和腿部抗阻力肌肉力量减弱(MRC 4级),面部偏左,手指-鼻子测试异常,运动障碍,无法进行串联步态。她接受了脑部核磁共振检查,但没有返回医院进行重新评估和手术。结果:脑MRI示小脑左侧肿块,大小4.44x3.93x4.93 cm,提示前庭神经鞘瘤。肿块还造成脑室闭塞,引起脑积水。结论:KWNP是一种不寻常的发现,导致似是而非的偏瘫,一种错误定位的神经体征。医生应该在偏瘫患者中认识到KWNP,特别是在占位性病变中。影像学检查可以帮助定位病变,以减少误诊和优化患者治疗。
{"title":"Paradoxical Hemiparesis from Cerebellopontine Angle Tumor: A Case Report","authors":"Maula Nuruddin Gaharu, James Gunawan","doi":"10.15850/ijihs.v11n2.2947","DOIUrl":"https://doi.org/10.15850/ijihs.v11n2.2947","url":null,"abstract":"Objective: To report a vestibular schwannoma in the cerebellopontine angle presenting with paradoxical hemiparesis with the Kernohan-Woltman Notch Phenomenon (KWNP).Methods: A 31-year-old female presented to the neurology clinic at Bhayangkara Hospital TK. I R. Said Sukanto, Indonesia, on 29 November 2021 with loss of balance, hearing, vision, and weakness in her left arm and leg. On physical examination, the patient had reduced left arm and leg muscle strengths against resistance (MRC grade 4), face deviation to the left, abnormal finger-to-nose test, dysdiadochokinesia, and inability to perform tandem gait. She was admitted for a brain MRI but did not return to the hospital for re-evaluation and surgery. Results: The brain MRI showed a mass on the left side of the cerebellum with a size of 4.44x3.93x4.93 cm, suggesting vestibular schwannoma. The mass also caused the obliteration of the ventricle, causing hydrocephalus.Conclusion:KWNP is an unusual finding resulting in a paradoxical hemiparesis, a false-localizing neurologic sign. Physicians should recognize KWNP in patients with hemiparesis, especially in space-occupying lesions. Imaging studies can help localize the lesion to minimize misdiagnosis and optimize patient treatment.","PeriodicalId":30637,"journal":{"name":"International Journal of Integrated Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135131170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcome of Posterior Cruciate Ligament Avulsion Fractures from Tibial Attachment Treated by Open Reduction and Internal Fixation 切开复位内固定治疗胫骨附着处后交叉韧带撕脱骨折的疗效
Pub Date : 2023-09-30 DOI: 10.15850/ijihs.v11n2.3471
Shouryashil V Khambalkar, Tanish C. Patil, Jaydeep K. Patil, Kapil R. Ghorpade, Nagesh Naik
Objectives: To analyze the clinical and functional outcomes of posterior cruciate ligament avulsion fractures treated by open reduction and internal fixation from tibial attachment.Methods: This observational study was conducted at the orthopedics department of a tertiary care medical college. Forty adult patients with PCL avulsion fractures were included in this study based on predefined inclusion and exclusion criteria. All patients were treated by open reduction and internal fixation. Patients were followed up for one year. The Lysholm scale and knee society score were used to assess functional outcomes. A p-value less than 0.05 was considered to be statistically significant.Results: Overall, 34 (75 %) males and 6 (15%) females participated in this study with an M: F ratio of 1:0.17. The mean age of affected patients was 37.3 +/- 7.34 years. Out of 40 patients, 29 (72.50%) patients sustained fractures secondary to road traffic accidents, while 7 (17.50%) had sports-related injuries. There was a highly significant improvement in the Lysholm and Knee Society scores from the time of presentation to the final follow-up (P<0.0001). Only 1 (2.5%) patient developed residual joint instability as evidenced by the drawer test result.Conclusion: Patients with posterior cruciate ligament avulsion fracture treated by Open reduction and internal fixation were found to have excellent results in terms of functional outcomes.
目的:分析胫骨附着体切开复位内固定治疗后交叉韧带撕脱骨折的临床和功能效果。方法:本观察性研究在某三级专科医学院骨科进行。40例成年PCL撕脱性骨折患者根据预先确定的纳入和排除标准纳入本研究。所有患者均行切开复位内固定治疗。患者随访1年。使用Lysholm量表和膝关节社会评分来评估功能预后。p值小于0.05被认为具有统计学意义。结果:总体而言,34名(75%)男性和6名(15%)女性参与了本研究,M: F比为1:0.17。患者的平均年龄为37.3±7.34岁。40例患者中,道路交通事故致骨折29例(72.50%),运动相关损伤7例(17.50%)。Lysholm and Knee Society评分从就诊到最后随访期间有显著改善(P<0.0001)。抽屉试验结果表明,仅有1例(2.5%)患者出现残余关节不稳定。结论:经切开复位内固定治疗后交叉韧带撕脱骨折在功能方面效果良好。
{"title":"Outcome of Posterior Cruciate Ligament Avulsion Fractures from Tibial Attachment Treated by Open Reduction and Internal Fixation","authors":"Shouryashil V Khambalkar, Tanish C. Patil, Jaydeep K. Patil, Kapil R. Ghorpade, Nagesh Naik","doi":"10.15850/ijihs.v11n2.3471","DOIUrl":"https://doi.org/10.15850/ijihs.v11n2.3471","url":null,"abstract":"Objectives: To analyze the clinical and functional outcomes of posterior cruciate ligament avulsion fractures treated by open reduction and internal fixation from tibial attachment.Methods: This observational study was conducted at the orthopedics department of a tertiary care medical college. Forty adult patients with PCL avulsion fractures were included in this study based on predefined inclusion and exclusion criteria. All patients were treated by open reduction and internal fixation. Patients were followed up for one year. The Lysholm scale and knee society score were used to assess functional outcomes. A p-value less than 0.05 was considered to be statistically significant.Results: Overall, 34 (75 %) males and 6 (15%) females participated in this study with an M: F ratio of 1:0.17. The mean age of affected patients was 37.3 +/- 7.34 years. Out of 40 patients, 29 (72.50%) patients sustained fractures secondary to road traffic accidents, while 7 (17.50%) had sports-related injuries. There was a highly significant improvement in the Lysholm and Knee Society scores from the time of presentation to the final follow-up (P<0.0001). Only 1 (2.5%) patient developed residual joint instability as evidenced by the drawer test result.Conclusion: Patients with posterior cruciate ligament avulsion fracture treated by Open reduction and internal fixation were found to have excellent results in terms of functional outcomes.","PeriodicalId":30637,"journal":{"name":"International Journal of Integrated Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135131184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between Comorbidities and COVID-19 Mortality: a Cross-Sectional Study in a Community Health Center in Indonesia 合并症与COVID-19死亡率之间的关系:印度尼西亚社区卫生中心的横断面研究
Pub Date : 2023-09-30 DOI: 10.15850/ijihs.v11n2.3216
Sutaip Sutaip, Dwi Sutiningsih, Mateus Sakundarno Adi, Sutra Diyana, Siti Rahayu, Nur Azizah Azzahra, Putri Andalusia Sarigando Banilai, Giyantolin Giyantolin
Objective: To analyze the risk factors for mortality and comorbidity of COVID-19 patients in a public health center work area in Indonesia.Methods: This was a cross-sectional observational analytic quantitative study using secondary data of 820 confirmed COVID-19 cases in Brebes Public Health Center work area during the period of June 2020–December 2021. Univariate and bivariate analyses were used to analyze the obtained data statistically with a p-value of <0.005 considered significant.Results: Of the 820 confirmed COVID-19 patients, 85.1% recovered and 15.0% died. Analysis on the characteristics of these cases showed that 51.2% females and 48.8 % males were included in this study, with 77.6% of them were <60 years old. No history of comorbidities was identified in 92.1% of the cases. In remaining cases with comorbidities, Diabetes Mellitus was recognized as the most prevalent (n=39, 4.8%). Results of the Chi-Square test demonstrated that comorbidity status (p-value = 0.001), place of quarantine (p p=0.000 p>0.05), and diabetes (p=0.000, OR=2.87, 95% CI 19 1.24-0280) were significantly associated with mortality.Conclusion: Comorbidity status, diabetes, and the place quarantine are risk factors for mortality among COVID-19 confirmed cases, especially in Brebes Public Health Center work area. Thus, it is important to increase knowledge about COVID-19 prevention and risks to prevent transmission among those with higher risks for mortality. Further studies on factors related to sustainable supports for COVID-19 patients are also necessary.
目的:分析印度尼西亚某公共卫生中心工作区域COVID-19患者死亡及合并症的危险因素。方法:对2020年6月- 2021年12月布雷布斯公共卫生中心工作区域820例新冠肺炎确诊病例进行横断面观察分析定量研究。采用单因素和双因素分析对获得的数据进行统计分析,p值为<0.005认为显著。结果:820例新冠肺炎确诊患者中,85.1%康复,15.0%死亡。对这些病例的特征进行分析,女性占51.2%,男性占48.8%,其中60岁的患者占77.6%。92.1%的病例无合并症史。在其余有合并症的病例中,糖尿病被认为是最普遍的(n=39, 4.8%)。卡方检验结果显示,共病状态(p值= 0.001)、检疫地点(p=0.000和gt;0.05)和糖尿病(p=0.000, OR=2.87, 95% CI 19 1.24-0280)与死亡率显著相关。结论:合并症、糖尿病和地方隔离是COVID-19确诊病例死亡的危险因素,特别是在布雷布斯公共卫生中心工作区域。因此,必须提高对COVID-19预防和风险的认识,以防止在死亡风险较高的人群中传播。还需要进一步研究与COVID-19患者可持续支持相关的因素。
{"title":"Association between Comorbidities and COVID-19 Mortality: a Cross-Sectional Study in a Community Health Center in Indonesia","authors":"Sutaip Sutaip, Dwi Sutiningsih, Mateus Sakundarno Adi, Sutra Diyana, Siti Rahayu, Nur Azizah Azzahra, Putri Andalusia Sarigando Banilai, Giyantolin Giyantolin","doi":"10.15850/ijihs.v11n2.3216","DOIUrl":"https://doi.org/10.15850/ijihs.v11n2.3216","url":null,"abstract":"Objective: To analyze the risk factors for mortality and comorbidity of COVID-19 patients in a public health center work area in Indonesia.Methods: This was a cross-sectional observational analytic quantitative study using secondary data of 820 confirmed COVID-19 cases in Brebes Public Health Center work area during the period of June 2020–December 2021. Univariate and bivariate analyses were used to analyze the obtained data statistically with a p-value of <0.005 considered significant.Results: Of the 820 confirmed COVID-19 patients, 85.1% recovered and 15.0% died. Analysis on the characteristics of these cases showed that 51.2% females and 48.8 % males were included in this study, with 77.6% of them were <60 years old. No history of comorbidities was identified in 92.1% of the cases. In remaining cases with comorbidities, Diabetes Mellitus was recognized as the most prevalent (n=39, 4.8%). Results of the Chi-Square test demonstrated that comorbidity status (p-value = 0.001), place of quarantine (p p=0.000 p>0.05), and diabetes (p=0.000, OR=2.87, 95% CI 19 1.24-0280) were significantly associated with mortality.Conclusion: Comorbidity status, diabetes, and the place quarantine are risk factors for mortality among COVID-19 confirmed cases, especially in Brebes Public Health Center work area. Thus, it is important to increase knowledge about COVID-19 prevention and risks to prevent transmission among those with higher risks for mortality. Further studies on factors related to sustainable supports for COVID-19 patients are also necessary.","PeriodicalId":30637,"journal":{"name":"International Journal of Integrated Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135131369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prophylactic Antibiotics Use in Pediatric Day Case Surgery: Is it Really Necessary? 预防性抗生素在儿科日间手术中的使用:真的有必要吗?
Pub Date : 2023-09-21 DOI: 10.51219/jih/chukwubuike-kevin-emeka/9
Okoloagu Nkiruka, Eze Thaddeus Chikaodili, Chukwubuike Kevin Emeka
performed, presence/absence of wound infection of the 2 groups of patients. Results: A total of 72 cases of pediatric day case surgeries were carried out during the study period with equal number of patients in each group. There was male predominance and the overall mean age of the patients at presentation was 50 months, with a range of 1 month to 14 years. Hydroceles and hernias were the most common clinical diagnoses. Overall, 15 (20.8%) patients developed post-operative complications and out of this number, equal number of patients (5) in each group developed wound infection. Conclusion: Prophylactic use of antibiotics prior to surgical procedures in children may appear routine. Howbeit, this randomized controlled study has shown that the rate of surgical site infection is the same whether prophylactic antibiotics were given or not. Therefore, prophylactic antibiotics may not be necessary in pediatric day case surgeries.
{"title":"Prophylactic Antibiotics Use in Pediatric Day Case Surgery: Is it Really Necessary?","authors":"Okoloagu Nkiruka, Eze Thaddeus Chikaodili, Chukwubuike Kevin Emeka","doi":"10.51219/jih/chukwubuike-kevin-emeka/9","DOIUrl":"https://doi.org/10.51219/jih/chukwubuike-kevin-emeka/9","url":null,"abstract":"performed, presence/absence of wound infection of the 2 groups of patients. Results: A total of 72 cases of pediatric day case surgeries were carried out during the study period with equal number of patients in each group. There was male predominance and the overall mean age of the patients at presentation was 50 months, with a range of 1 month to 14 years. Hydroceles and hernias were the most common clinical diagnoses. Overall, 15 (20.8%) patients developed post-operative complications and out of this number, equal number of patients (5) in each group developed wound infection. Conclusion: Prophylactic use of antibiotics prior to surgical procedures in children may appear routine. Howbeit, this randomized controlled study has shown that the rate of surgical site infection is the same whether prophylactic antibiotics were given or not. Therefore, prophylactic antibiotics may not be necessary in pediatric day case surgeries.","PeriodicalId":30637,"journal":{"name":"International Journal of Integrated Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136239378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of COVID-19 Pandemic in Oncological Debut at Pediatric Emergency Department COVID-19大流行对儿科急诊科肿瘤首发的影响
Pub Date : 2023-09-10 DOI: 10.51219/jih/marta-diaz-miguel/10
Marta Diaz Miguel, Adrià Martos Utande, Victoria Trenchs Sainz de la Maza, Carles Luaces
{"title":"Impact of COVID-19 Pandemic in Oncological Debut at Pediatric Emergency Department","authors":"Marta Diaz Miguel, Adrià Martos Utande, Victoria Trenchs Sainz de la Maza, Carles Luaces","doi":"10.51219/jih/marta-diaz-miguel/10","DOIUrl":"https://doi.org/10.51219/jih/marta-diaz-miguel/10","url":null,"abstract":"","PeriodicalId":30637,"journal":{"name":"International Journal of Integrated Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136108512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microbiota and COVID -19: Microbial Dysbiosis 微生物群与COVID -19:微生物生态失调
Pub Date : 2023-09-06 DOI: 10.51219/jih/zahra--meshkat/8
Mostafa Fazeli, Nader Yazdinezhad, Zahra Meshkat
be beneficial in COVID-19 management and improving vaccine efficiency
{"title":"Microbiota and COVID -19: Microbial Dysbiosis","authors":"Mostafa Fazeli, Nader Yazdinezhad, Zahra Meshkat","doi":"10.51219/jih/zahra--meshkat/8","DOIUrl":"https://doi.org/10.51219/jih/zahra--meshkat/8","url":null,"abstract":"be beneficial in COVID-19 management and improving vaccine efficiency","PeriodicalId":30637,"journal":{"name":"International Journal of Integrated Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135205204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microbiota and COVID -19: Microbial Dysbiosis 微生物群与COVID -19:微生物生态失调
Pub Date : 2023-09-06 DOI: 10.51219/jih/zahra-meshkat/8
Mostafa Fazeli, Nader Yazdinezhad, Zahra Meshkat
{"title":"Microbiota and COVID -19: Microbial Dysbiosis","authors":"Mostafa Fazeli, Nader Yazdinezhad, Zahra Meshkat","doi":"10.51219/jih/zahra-meshkat/8","DOIUrl":"https://doi.org/10.51219/jih/zahra-meshkat/8","url":null,"abstract":"","PeriodicalId":30637,"journal":{"name":"International Journal of Integrated Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135205203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thyroid Profile and Serum Lipid Level in Women with Normal Pregnancy 正常妊娠妇女的甲状腺特征和血脂水平
Pub Date : 2023-09-01 DOI: 10.15850/ijihs.v11n2.3460
Raj Kumar, Sudeep Kumar, Manisha Arora, Dinesh Kumar, Sumesh Prasad Sah, Shivani Sharma
Objective: To evaluate the changes in thyroid profile and serum lipid level in normal pregnancy. Methods: This observational study was conducted at the Department of Biochemistry of Santosh Medical College, Ghaziabad, UP, India, from June 2021 to February 2022. In this study, 200 average pregnant women were enrolled. The thyroid profile was estimated using the ELISA method, and the lipid profile was measured using the enzymatic kit method. All data were expressed as means and standard deviations, and SPSS version 17 was used for statistical analysis. Results: This observational study observed that the mean T3, T4, and TSH levels increased significantly in the second trimester compared to the first trimester. In contrast, the mean value of T3, T4, and TSH decreased in the third trimester as compared to the second trimester. The mean levels of total cholesterol, triglyceride, and LDL-cholesterol increased significantly, while the mean value of HDL-cholesterol decreased significantly in the second and third trimesters when compared to the first trimester. Conclusion: This study demonstrated abnormal lipid and thyroid metabolism. Changes in thyroid profile may be associated with adverse obstetric outcomes. The altered lipid parameters, mainly High TG and low HDL-C concentrations, may promote vascular dysfunction and oxidative stress.
目的:探讨正常妊娠妇女甲状腺功能及血脂水平的变化。方法:本观察性研究于2021年6月至2022年2月在印度北方邦加济阿巴德Santosh医学院生物化学系进行。在这项研究中,200名普通孕妇参加了研究。采用酶联免疫吸附试验(ELISA)法测定甲状腺特征,采用酶促试剂盒法测定血脂特征。所有数据均以均数和标准差表示,采用SPSS version 17进行统计分析。结果:本观察性研究发现,与妊娠早期相比,妊娠中期的平均T3、T4和TSH水平显著升高。相反,与妊娠中期相比,妊娠晚期T3、T4和TSH的平均值有所下降。总胆固醇、甘油三酯和低密度脂蛋白胆固醇的平均水平显著升高,而高密度脂蛋白胆固醇的平均值在妊娠中期和晚期与妊娠早期相比显著降低。结论:本研究显示血脂和甲状腺代谢异常。甲状腺特征的改变可能与不良的产科结局有关。脂质参数的改变,主要是高TG和低HDL-C浓度,可能促进血管功能障碍和氧化应激。
{"title":"Thyroid Profile and Serum Lipid Level in Women with Normal Pregnancy","authors":"Raj Kumar, Sudeep Kumar, Manisha Arora, Dinesh Kumar, Sumesh Prasad Sah, Shivani Sharma","doi":"10.15850/ijihs.v11n2.3460","DOIUrl":"https://doi.org/10.15850/ijihs.v11n2.3460","url":null,"abstract":"Objective: To evaluate the changes in thyroid profile and serum lipid level in normal pregnancy. Methods: This observational study was conducted at the Department of Biochemistry of Santosh Medical College, Ghaziabad, UP, India, from June 2021 to February 2022. In this study, 200 average pregnant women were enrolled. The thyroid profile was estimated using the ELISA method, and the lipid profile was measured using the enzymatic kit method. All data were expressed as means and standard deviations, and SPSS version 17 was used for statistical analysis. Results: This observational study observed that the mean T3, T4, and TSH levels increased significantly in the second trimester compared to the first trimester. In contrast, the mean value of T3, T4, and TSH decreased in the third trimester as compared to the second trimester. The mean levels of total cholesterol, triglyceride, and LDL-cholesterol increased significantly, while the mean value of HDL-cholesterol decreased significantly in the second and third trimesters when compared to the first trimester. Conclusion: This study demonstrated abnormal lipid and thyroid metabolism. Changes in thyroid profile may be associated with adverse obstetric outcomes. The altered lipid parameters, mainly High TG and low HDL-C concentrations, may promote vascular dysfunction and oxidative stress.","PeriodicalId":30637,"journal":{"name":"International Journal of Integrated Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135738080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The PEACE Model Canvas (PMC): Helping People Prepare for Change 和平模型画布(PMC):帮助人们为变革做好准备
Pub Date : 2023-08-03 DOI: 10.51219/jih/dhally-m-menda/7
Dhally M. Menda
it provides individuals with a structured and systematic approach to understanding their thoughts, emotions, and actions. Secondly, the PMC enables individuals to challenge and reshape their existing beliefs and assumptions, fostering a more flexible and adaptable mindset. Thirdly, the PMC facilitates better communication and collaboration with others by promoting a shared understanding and language for discussing complex problem behaviours. Furthermore, the PMC empowers individuals to anticipate and navigate challenges more effectively, as it provides a framework for considering potential consequences of problem behaviours, analyzing alternatives solutions, and making informed choices. Lastly, the PMC supports continuous learning and personal growth, as individuals become more self-aware, reflective, and open to acquiring new knowledge and skills and change behaviour. Overall, using the PEACE Model Canvas offers a transformative pathway to behaviour change, leading to improved well-being, enhanced problem-solving abilities, and greater overall success in various aspects of life.
它为个人提供了一种结构化的、系统的方法来理解他们的思想、情感和行为。其次,PMC使个人能够挑战和重塑他们现有的信念和假设,培养更灵活和适应性强的心态。第三,PMC通过促进共同理解和讨论复杂问题行为的语言,促进了与他人更好的沟通和协作。此外,PMC使个人能够更有效地预测和应对挑战,因为它提供了一个框架,可以考虑问题行为的潜在后果,分析替代解决方案,并做出明智的选择。最后,PMC支持持续学习和个人成长,因为个人变得更加自我意识,反思,并开放获取新的知识和技能,并改变行为。总体而言,使用PEACE模型画布为行为改变提供了一条变革性的途径,从而改善了幸福感,增强了解决问题的能力,并在生活的各个方面取得了更大的整体成功。
{"title":"The PEACE Model Canvas (PMC): Helping People Prepare for Change","authors":"Dhally M. Menda","doi":"10.51219/jih/dhally-m-menda/7","DOIUrl":"https://doi.org/10.51219/jih/dhally-m-menda/7","url":null,"abstract":"it provides individuals with a structured and systematic approach to understanding their thoughts, emotions, and actions. Secondly, the PMC enables individuals to challenge and reshape their existing beliefs and assumptions, fostering a more flexible and adaptable mindset. Thirdly, the PMC facilitates better communication and collaboration with others by promoting a shared understanding and language for discussing complex problem behaviours. Furthermore, the PMC empowers individuals to anticipate and navigate challenges more effectively, as it provides a framework for considering potential consequences of problem behaviours, analyzing alternatives solutions, and making informed choices. Lastly, the PMC supports continuous learning and personal growth, as individuals become more self-aware, reflective, and open to acquiring new knowledge and skills and change behaviour. Overall, using the PEACE Model Canvas offers a transformative pathway to behaviour change, leading to improved well-being, enhanced problem-solving abilities, and greater overall success in various aspects of life.","PeriodicalId":30637,"journal":{"name":"International Journal of Integrated Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79898763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stakekold ZXSY Brazil, Precision Medicine in Pediatric Clinic: Reward Deficiency Syndrome (RDS) Is Surprisingly Evolving and Found Everywhere: Is It "Blowing in the Wind"? Yes, but how Syndrome Z. 儿科临床的精准医学:奖励缺乏症(RDS)正在惊人地进化并无处不在:它是“在风中吹”吗?是的,但是Z综合症。
Pub Date : 2023-06-05 DOI: 10.51219/jih/furlanetto-m-l-jr/6
Furlanetto M L Jr
Much neurobiological and psychological knowledge about brain development and maturation in pregnancy and early childhood should be evaluated simultaneously, due to several underlying pathophysiological findings, because with proven clinical evidence, with time greater than twenty years, such as situations of Adverse Emotions in Childhood (ACE), Post Traumatic Stress Disorder (PTSD), and recently the absence/ deficit of oxytoninergic neurons responsible for family synchrony, cause a series of aberrant pathophysiological effects, with inflammatory, behavioral, cognitive, affective and social impairments [1].
由于一些潜在的病理生理学发现,许多关于怀孕和幼儿期大脑发育和成熟的神经生物学和心理学知识应该同时进行评估,因为有经过证实的临床证据,时间超过20年,例如童年不良情绪(ACE),创伤后应激障碍(PTSD),以及最近负责家庭同步的催产素能神经元的缺失/缺陷,引起一系列异常的病理生理效应,包括炎症、行为、认知、情感和社会障碍。
{"title":"Stakekold ZXSY Brazil, Precision Medicine in Pediatric Clinic: Reward Deficiency Syndrome (RDS) Is Surprisingly Evolving and Found Everywhere: Is It \"Blowing in the Wind\"? Yes, but how Syndrome Z.","authors":"Furlanetto M L Jr","doi":"10.51219/jih/furlanetto-m-l-jr/6","DOIUrl":"https://doi.org/10.51219/jih/furlanetto-m-l-jr/6","url":null,"abstract":"Much neurobiological and psychological knowledge about brain development and maturation in pregnancy and early childhood should be evaluated simultaneously, due to several underlying pathophysiological findings, because with proven clinical evidence, with time greater than twenty years, such as situations of Adverse Emotions in Childhood (ACE), Post Traumatic Stress Disorder (PTSD), and recently the absence/ deficit of oxytoninergic neurons responsible for family synchrony, cause a series of aberrant pathophysiological effects, with inflammatory, behavioral, cognitive, affective and social impairments [1].","PeriodicalId":30637,"journal":{"name":"International Journal of Integrated Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90287115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International Journal of Integrated Health Sciences
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1