Pub Date : 2016-09-01DOI: 10.5455/ACES.20151102085951
G. Wright, A. Davis, T. Koehler, B. Goslin, M. Chung
Objective: Solid-pseudopapillary tumor of the pancreas (SPTP) is a rare neoplasm that has been investigated only in individual case series from individual institutions. Here, the goal was to perform a population-based analysis of these rare tumors. Methods: A query of the Surveillance, Epidemiology, and End Results (SEER) database was made for patients with malignant SPTP and pancreatic ductal adenocarcinoma (PDAC) from 2001-2010. The primary outcome measure was five-year overall survival. Cox regression analyses were performed using age, race, gender, tumor location, stage of tumor, and histologic type. Results: 107 patients with SPTP and 53,353 with PDAC were identified for study. Patients with SPTP were younger (p
{"title":"Solid pseudopapillary tumor of the pancreas: A population-based comparison with pancreatic ductal adenocarcinoma","authors":"G. Wright, A. Davis, T. Koehler, B. Goslin, M. Chung","doi":"10.5455/ACES.20151102085951","DOIUrl":"https://doi.org/10.5455/ACES.20151102085951","url":null,"abstract":"Objective: Solid-pseudopapillary tumor of the pancreas (SPTP) is a rare neoplasm that has been investigated only in individual case series from individual institutions. Here, the goal was to perform a population-based analysis of these rare tumors. \u0000Methods: A query of the Surveillance, Epidemiology, and End Results (SEER) database was made for patients with malignant SPTP and pancreatic ductal adenocarcinoma (PDAC) from 2001-2010. The primary outcome measure was five-year overall survival. Cox regression analyses were performed using age, race, gender, tumor location, stage of tumor, and histologic type. \u0000Results: 107 patients with SPTP and 53,353 with PDAC were identified for study. Patients with SPTP were younger (p","PeriodicalId":30641,"journal":{"name":"Archives of Clinical and Experimental Surgery","volume":"5 1","pages":"148-153"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70765884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-06-01DOI: 10.5455/ACES.20140810011530
S. Gorgulu, Z. Kılbaş, R. Yıldız, Erkan Ozturk, M. Menteş, M. Urkan
Sentinel lymph node (SLN) biopsy is accepted as the gold standard procedure for assessing the status of the axillary lymph node in clinically node-negative breast cancer. The intraoperative blue dye injection is commonly performed to localize the SLN. Systemic allergic complications related to blue dye injection have been well documented, but local adverse effects requiring surgical excision are extremely rare. We report an infrequent case of skin and subcutaneous tissue necrosis following subdermal injection of methylen blue (MB) dye. A 48-year-old female, diagnosed with infiltrating ductal carcinoma, was treated by her initial surgeon with lumpectomy and SLN biopsy. For identification of the SLN, periareolar subdermal injection of 4 ml of 1% MB dye was performed. The patient was seen 10 days following discharge when it was noticed that the periareolar injection sites in the left breast had become necrotic. Since the necrosis invaded the majority of breast, mastectomy had to be performed. Histopathologic examination revealed necrosis of the skin and subcutaneous tissue of the left breast. Although the use of MB dye for SLN biopsy in breast cancer has few systemic reactions, its use has been associated with a number of undesired local complications. Deep parenchymal injections are recommended in order to avoid blue dye-associated skin lesions.
{"title":"Methylen blue dye related breast skin necrosis requiring mastectomy: Case report","authors":"S. Gorgulu, Z. Kılbaş, R. Yıldız, Erkan Ozturk, M. Menteş, M. Urkan","doi":"10.5455/ACES.20140810011530","DOIUrl":"https://doi.org/10.5455/ACES.20140810011530","url":null,"abstract":"Sentinel lymph node (SLN) biopsy is accepted as the gold standard procedure for assessing the status of the axillary lymph node in clinically node-negative breast cancer. The intraoperative blue dye injection is commonly performed to localize the SLN. Systemic allergic complications related to blue dye injection have been well documented, but local adverse effects requiring surgical excision are extremely rare. We report an infrequent case of skin and subcutaneous tissue necrosis following subdermal injection of methylen blue (MB) dye. A 48-year-old female, diagnosed with infiltrating ductal carcinoma, was treated by her initial surgeon with lumpectomy and SLN biopsy. For identification of the SLN, periareolar subdermal injection of 4 ml of 1% MB dye was performed. The patient was seen 10 days following discharge when it was noticed that the periareolar injection sites in the left breast had become necrotic. Since the necrosis invaded the majority of breast, mastectomy had to be performed. Histopathologic examination revealed necrosis of the skin and subcutaneous tissue of the left breast. Although the use of MB dye for SLN biopsy in breast cancer has few systemic reactions, its use has been associated with a number of undesired local complications. Deep parenchymal injections are recommended in order to avoid blue dye-associated skin lesions.","PeriodicalId":30641,"journal":{"name":"Archives of Clinical and Experimental Surgery","volume":"526 1","pages":"121-123"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70764093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-06-01DOI: 10.5455/ACES.20150920025832
H. Bayraktar, S. Ekinci, F. Ozcelik, M. Sonmez, C. Tamam
Objective: Arthroscopic surgery is currently a well-known treatment method for meniscal pathologies. This study aims to compare conservative and surgical methods in patients with meniscopathy. Materials and Methods: The retrospective analyses of 68 patients with meniscal tear were included in this study. Patients were divided into two groups: a medical treatment group (MTG) and a surgical treatment group (STG). Diagnosis was perfomed by physical examination and magnetic resonance imaging (MRI). All patients were evaluated before and after treatment with main pain score (MPS), International Knee Documentation Committee (IKDC) score, body mass index (BMI), and Ultrasensitive C-reactive protein (US-CRP). In the MTG group, 31 patients underwent medical treatment with naproxen sodium for three days, ice application, activity modification, and muscle exercises. In the STG group, 37 patients underwent arthroscopic partial menisectomy and naproxen sodium for three days. Parameters characterizing pretreatment and posttreatment states were compared statistically. The MPS, IKDC, BMI, and US-CRP values of both groups were recorded at baseline and three months after treatment. Results: Surgical treatment group (STG): In this group, after three months of treatment, MPS decreased and IKDC scores increased significantly when compared with baseline (P 0.1799, respectively). Medical treatment group (MTG): In this group, MPS decreased and BMI increased significantly after three months compared with preoperative scores (P 0.05, respectively). Conclusion: IKDC and pain scores of patients with meniscal tear improved by arthroscopic knee surgery.
{"title":"Comparison of conservative and surgical treatment methods in patients with meniscopathy","authors":"H. Bayraktar, S. Ekinci, F. Ozcelik, M. Sonmez, C. Tamam","doi":"10.5455/ACES.20150920025832","DOIUrl":"https://doi.org/10.5455/ACES.20150920025832","url":null,"abstract":"Objective: Arthroscopic surgery is currently a well-known treatment method for meniscal pathologies. This study aims to compare conservative and surgical methods in patients with meniscopathy. \u0000Materials and Methods: The retrospective analyses of 68 patients with meniscal tear were included in this study. Patients were divided into two groups: a medical treatment group (MTG) and a surgical treatment group (STG). Diagnosis was perfomed by physical examination and magnetic resonance imaging (MRI). All patients were evaluated before and after treatment with main pain score (MPS), International Knee Documentation Committee (IKDC) score, body mass index (BMI), and Ultrasensitive C-reactive protein (US-CRP). \u0000In the MTG group, 31 patients underwent medical treatment with naproxen sodium for three days, ice application, activity modification, and muscle exercises. In the STG group, 37 patients underwent arthroscopic partial menisectomy and naproxen sodium for three days. Parameters characterizing pretreatment and posttreatment states were compared statistically. The MPS, IKDC, BMI, and US-CRP values of both groups were recorded at baseline and three months after treatment. \u0000Results: \u0000Surgical treatment group (STG): In this group, after three months of treatment, MPS decreased and IKDC scores increased significantly when compared with baseline (P 0.1799, respectively). \u0000Medical treatment group (MTG): In this group, MPS decreased and BMI increased significantly after three months compared with preoperative scores (P 0.05, respectively). \u0000Conclusion: IKDC and pain scores of patients with meniscal tear improved by arthroscopic knee surgery.","PeriodicalId":30641,"journal":{"name":"Archives of Clinical and Experimental Surgery","volume":"5 1","pages":"78-84"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70765323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-06-01DOI: 10.5455/ACES.20150508124321
N. Şahin, A. Atik, S. Sargin
Hypermobility is defined as an abnormally increased range of motion of a joint resulting from the excessive laxity of the soft tissues. This paper is focused on this commonly forgotten cause of several morbidities. The etiology of hypermobility is not very well known. One decade ago, joint hypermobility syndrome was considered as a benign condition, but now it is recognized as a significant contributor to chronic musculoskeletal pain, besides impacting on other organs. Patients with joint hypermobility syndrome often have diffuse, chronic complaints that are inconsistent with the musculoskeletal system. Chronic pain may cause loss of proprioception and so increased sensitivity to microtrauma, premature osteoarthritis de- velopment, soft tissue problems, psychosocial disorders, and neurophysiological deficiencies. Osteoarthritis, pes planus, mechanical low back pain, and soft tissue rheumatisms are frequent musculoskeletal findings as well as subluxations, thoracic outlet syndrome, rectal and uterine prolapses, hernias, and stress incontinence. Joint hypermobility syndrome’s treatment is not easy, and nonsteroidal anti-inflammatory drugs are not usually effective or adequate. Proprioceptive and strengthening exercises have been reported to have supportive and therapeutic effects, but we have limited data on this issue. Joint hypermobility syndrome must be accepted as a multisystem connective tissue disorder rather than just joint laxities. As a result; clinicians must be aware of complexities of connective tissue disorders and comorbidities.
{"title":"Joint hypermobility syndrome and related pain","authors":"N. Şahin, A. Atik, S. Sargin","doi":"10.5455/ACES.20150508124321","DOIUrl":"https://doi.org/10.5455/ACES.20150508124321","url":null,"abstract":"Hypermobility is defined as an abnormally increased range of motion of a joint resulting from the excessive laxity of the soft tissues. This paper is focused on this commonly forgotten cause of several morbidities. The etiology of hypermobility is not very well known. One decade ago, joint hypermobility syndrome was considered as a benign condition, but now it is recognized as a significant contributor to chronic musculoskeletal pain, besides impacting on other organs. Patients with joint hypermobility syndrome often have diffuse, chronic complaints that are inconsistent with the musculoskeletal system. Chronic pain may cause loss of proprioception and so increased sensitivity to microtrauma, premature osteoarthritis de- velopment, soft tissue problems, psychosocial disorders, and neurophysiological deficiencies. Osteoarthritis, pes planus, mechanical low back pain, and soft tissue rheumatisms are frequent musculoskeletal findings as well as subluxations, thoracic outlet syndrome, rectal and uterine prolapses, hernias, and stress incontinence. Joint hypermobility syndrome’s treatment is not easy, and nonsteroidal anti-inflammatory drugs are not usually effective or adequate. Proprioceptive and strengthening exercises have been reported to have supportive and therapeutic effects, but we have limited data on this issue. Joint hypermobility syndrome must be accepted as a multisystem connective tissue disorder rather than just joint laxities. As a result; clinicians must be aware of complexities of connective tissue disorders and comorbidities.","PeriodicalId":30641,"journal":{"name":"Archives of Clinical and Experimental Surgery","volume":"41 1","pages":"105-112"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70764517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-03-01DOI: 10.5455/ACES.20140323104904
P. Yazıcı, R. Gocmen, F. Yuzbasioglu
Isolated traumatic rupture of the pancreas is an uncommon presentation with a rate of less than 5% of cases of major abdominal trauma. The proper management of peripancreatic fluid collections following pancreatic trauma is still uncertain. We present a patient with isolated pancreatic injury that was managed with percutaneous drainage. A 22-year-old male patient, who had fallen from a tree 3 days previously, was admitted to our clinic with symptoms of vomiting and abdominal distention. Laboratory results demonstrated leucocytosis (20.100/mm
{"title":"Percutaneous drainage for isolated pancreatic injury: A minimally invasive solution","authors":"P. Yazıcı, R. Gocmen, F. Yuzbasioglu","doi":"10.5455/ACES.20140323104904","DOIUrl":"https://doi.org/10.5455/ACES.20140323104904","url":null,"abstract":"Isolated traumatic rupture of the pancreas is an uncommon presentation with a rate of less than 5% of cases of major abdominal trauma. The proper management of peripancreatic fluid collections following pancreatic trauma is still uncertain. We present a patient with isolated pancreatic injury that was managed with percutaneous drainage. A 22-year-old male patient, who had fallen from a tree 3 days previously, was admitted to our clinic with symptoms of vomiting and abdominal distention. Laboratory results demonstrated leucocytosis (20.100/mm","PeriodicalId":30641,"journal":{"name":"Archives of Clinical and Experimental Surgery","volume":"5 1","pages":"52-55"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70764409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.5455/aces.20140710064516
A. Gaffey, L. Litzky, S. Singhal
The rates of melanoma have increased over the past 30 years. Malignant melanoma most commonly occurs in the skin with secondary involvement of other organs. Here, we present an extremely rare case of malignant melanoma of the mediastinum with presentation of superior vena cava syndrome without clinical evidence of extrathoracic disease. The incidence of this clinical presentation is uncommon, resulting in only a handful of case reports in the literature.
{"title":"Primary mediastinal melanoma presenting as superior vena cava syndrome: A case study","authors":"A. Gaffey, L. Litzky, S. Singhal","doi":"10.5455/aces.20140710064516","DOIUrl":"https://doi.org/10.5455/aces.20140710064516","url":null,"abstract":"The rates of melanoma have increased over the past 30 years. Malignant melanoma most commonly occurs in the skin with secondary involvement of other organs. Here, we present an extremely rare case of malignant melanoma of the mediastinum with presentation of superior vena cava syndrome without clinical evidence of extrathoracic disease. The incidence of this clinical presentation is uncommon, resulting in only a handful of case reports in the literature.","PeriodicalId":30641,"journal":{"name":"Archives of Clinical and Experimental Surgery","volume":"5 1","pages":"56-58"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70764028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.5455/ACES.20140714024758
A. Cariati, G. Bottino, P. Diviacco, A. D. Negri, E. Moraglia, V. Belgrano, I. Leale, E. Piromalli, R. Fornaro, Mauro Nahun, E. Andorno
Biliary tract cysts are a group of rare congenital diseases that have been classified by Todani in 8 types. Hepaticojejunostomy has been the preferred intervention for Type I and IV biliary cysts. It has been postulated that, due to the low incidence of cancerization of Types II and III biliary cysts, a less invasive approach could be suggested, namely cyst resection in Type II, and endoscopic sphincterotomy with opening of choledochocele in small (
{"title":"Pitfalls and fatal complications after iterative endoscopic retrograde cholangiopancreatography or percutaneous transhepatic cholangiography management of biliary tract cysts. When to do open surgery (cyst resection; hepaticojejunostomy) or liver transplant? -","authors":"A. Cariati, G. Bottino, P. Diviacco, A. D. Negri, E. Moraglia, V. Belgrano, I. Leale, E. Piromalli, R. Fornaro, Mauro Nahun, E. Andorno","doi":"10.5455/ACES.20140714024758","DOIUrl":"https://doi.org/10.5455/ACES.20140714024758","url":null,"abstract":"Biliary tract cysts are a group of rare congenital diseases that have been classified by Todani in 8 types. Hepaticojejunostomy has been the preferred intervention for Type I and IV biliary cysts. It has been postulated that, due to the low incidence of cancerization of Types II and III biliary cysts, a less invasive approach could be suggested, namely cyst resection in Type II, and endoscopic sphincterotomy with opening of choledochocele in small (","PeriodicalId":30641,"journal":{"name":"Archives of Clinical and Experimental Surgery","volume":"5 1","pages":"128-133"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70764046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.5455/aces.20160127010538
S. Basat, F. Ceran, İlker Üsçetin, Ì. Akan, Oğuzhan Demirel, M. Bozkurt
Background: Gynecomastia is a benign enlargement of breast tissue that occurs especially during adolescence in males and generally requires treatment. Although most of cases are idiopathic and bilateral, there are instances that require spe- cial attention and be given unilateral status. In this study, the aim was to evaluate management of unilateral gynecomastia. Methods: For this study, 23 male patients admitted to the authors’ clinic between 2010 and2013 diagnosed with grade 2A and 2B unilateal gynecomastia were reviewed retrospectively. The patients’ detailed medical history and physical exami- nation notes, laboratory test results, history of medication use and photographs were examined. Mean follow-up time was 13.4 months. Results: 11 patients were treated by strictly gland excision, four patients with only liposuction and eight patients with gland excision combined with liposuction. Gynecomastia was seen on the left side of the chest in 13 patients and on the right side in 10 patients. There were no complications. The specimens did not reveal any malignant causes. Conclusion: Although most cases gynecomastia are idiopathic and bilateral, there are instances that require special at- tention and should be given unilateral status. Detailed evaluation including physical examination, history of drug use and concomitant medical disorders should be considered.
{"title":"Unilateral gynecomastia: The assessment of 23 patients -","authors":"S. Basat, F. Ceran, İlker Üsçetin, Ì. Akan, Oğuzhan Demirel, M. Bozkurt","doi":"10.5455/aces.20160127010538","DOIUrl":"https://doi.org/10.5455/aces.20160127010538","url":null,"abstract":"Background: Gynecomastia is a benign enlargement of breast tissue that occurs especially during adolescence in males and generally requires treatment. Although most of cases are idiopathic and bilateral, there are instances that require spe- cial attention and be given unilateral status. In this study, the aim was to evaluate management of unilateral gynecomastia. Methods: For this study, 23 male patients admitted to the authors’ clinic between 2010 and2013 diagnosed with grade 2A and 2B unilateal gynecomastia were reviewed retrospectively. The patients’ detailed medical history and physical exami- nation notes, laboratory test results, history of medication use and photographs were examined. Mean follow-up time was 13.4 months. Results: 11 patients were treated by strictly gland excision, four patients with only liposuction and eight patients with gland excision combined with liposuction. Gynecomastia was seen on the left side of the chest in 13 patients and on the right side in 10 patients. There were no complications. The specimens did not reveal any malignant causes. Conclusion: Although most cases gynecomastia are idiopathic and bilateral, there are instances that require special at- tention and should be given unilateral status. Detailed evaluation including physical examination, history of drug use and concomitant medical disorders should be considered.","PeriodicalId":30641,"journal":{"name":"Archives of Clinical and Experimental Surgery","volume":"5 1","pages":"206-210"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70765490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.5455/ACES.20141030075642
H. Verma, A. Dass, S. Singhal, N. Gupta, Amrinder Kaur
Schwannomas are benign tumors that originate from the Schwann cells of the nerve sheath. They can arise from any myelinated nerve. The pre-operative diagnosis of schwannoma is difficult and should be suggested by clinical features and supported by investigations based on techniques such as ultrasonography, computed tomography (CT), magnetic resonance imaging, and fine-needle aspiration cytology. Schawannomas can present with very subtle symptoms or morbid sequel. A 19-year-old male patient presented with 6 months history of swelling in the upper left side part of the neck. Local examination showed a 5 cm A— 3 cm single globular mass in the left suboccipital region. The contrast enhanced CT scan showed a 44 mm A— 46 mm A— 39 mm well defined heterogeneous mildly enhancing mass on the left side of the upper three cervical vertebras abutting them. The mass was excised under general anesthesia by transcervical approach. After extensive search of English literature we came across only three case reports where schwannoma of greater occipital nerve presented with neuralgia.
神经鞘瘤是一种良性肿瘤，起源于神经鞘的雪旺细胞。它们可以产生于任何有髓神经。神经鞘瘤的术前诊断是困难的，应根据临床特征提出建议，并辅以超声、计算机断层扫描(CT)、磁共振成像和细针穿刺细胞学等技术的检查。沙湾鞘瘤可表现为非常细微的症状或病态的后遗症。19岁男性患者，颈部左上部肿胀6个月。局部检查显示在左侧枕下区有一个5cm - 3cm的单球状肿块。CT增强扫描显示，在靠近它们的上三个颈椎左侧，有一个44 mm a - 46 mm a - 39 mm清晰、不均匀的轻度增强肿块。肿块在全身麻醉下经颈入路切除。在大量查阅英文文献后，我们发现只有3例枕骨大神经鞘瘤表现为神经痛。
{"title":"Schwannoma causing greater occipital nerve neuralgia: Case report -","authors":"H. Verma, A. Dass, S. Singhal, N. Gupta, Amrinder Kaur","doi":"10.5455/ACES.20141030075642","DOIUrl":"https://doi.org/10.5455/ACES.20141030075642","url":null,"abstract":"Schwannomas are benign tumors that originate from the Schwann cells of the nerve sheath. They can arise from any myelinated nerve. The pre-operative diagnosis of schwannoma is difficult and should be suggested by clinical features and supported by investigations based on techniques such as ultrasonography, computed tomography (CT), magnetic resonance imaging, and fine-needle aspiration cytology. Schawannomas can present with very subtle symptoms or morbid sequel. A 19-year-old male patient presented with 6 months history of swelling in the upper left side part of the neck. Local examination showed a 5 cm A— 3 cm single globular mass in the left suboccipital region. The contrast enhanced CT scan showed a 44 mm A— 46 mm A— 39 mm well defined heterogeneous mildly enhancing mass on the left side of the upper three cervical vertebras abutting them. The mass was excised under general anesthesia by transcervical approach. After extensive search of English literature we came across only three case reports where schwannoma of greater occipital nerve presented with neuralgia.","PeriodicalId":30641,"journal":{"name":"Archives of Clinical and Experimental Surgery","volume":"5 1","pages":"59-62"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70764452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.5455/aces.20150508103342
Yilmaz Polat, Hasan Baki, Altinsoy Altinsoy, Hi Hi, lal Polat, B. Kanat, Seli Seli, M. Sozen, Mehmet Dal
Intrathoracic goiters are defined as the extension of the thyroid gland into the mediastinum. Superior Vena Cava (SVC) syndrome due to the compression of major vessels can be seen in these patients. Most cases of SVC syndrome occur as a complication of malignancy. A 75-year-old female, non-smoker, was admitted with complaints of the midline neck swell ing for the past 45 years, mild puffiness of face, breathlessness on lying down and dry cough for last 5 years. On clinical examination, there was a massive grade IV thyromegaly. Neck computed tomography revealed a heterogeneous, hyper -trophic, nodular thyroid gland with multiple calcification and mediastinal extension with narrowed trachea. Intraoperatively, there was a huge retrosternal thyroid gland compression of the right brachiocephalic vein, the brachiocephalic trunk from behind the vessel and the right carotid artery along with the right internal jugular vein. Pathological examination showed a nodular colloid goitre without signs of malignancy. When SVC syndrome is secondary to benign thyroid disease, total thyroidectomy should be performed. Abstract Objective: To evaluate the changes in the number of Langerhans Cells (LC) observed in the epithelium of smokeless tobacco (SLT-induced) lesions. Methods: Microscopic sections from biopsies carried out in the buccal mucosa of twenty patients, who were chronic users of smokeless tobacco (SLT), were utilized. For the control group, twenty non-SLT users of SLT with normal mucosa were selected. Th e sections were studied with routine coloring and were immunostained for S-100, CD1a, Ki-67 and p63. Th ese data were statistically analyzed by the Student’s t-test to investigate the di ff erences in the expression of immune markers in normal mucosa and in SLT-induced leukoplakia lesions. Results: Th ere was a signi fi cant di ff erence in the immunolabeling of all markers between normal mucosa and SLT-induced lesions (p<0.001). Th e leukoplakia lesions in chronic SLT users demonstrated a signi fi cant increase in the number of Langerhans cells and in the absence of epithelial dysplasia. Conclusion: Th e increase in the number of these cells represents the initial stage of leukoplakia.
{"title":"Superior vena cava syndrome caused by a benign intrathoracic goiter","authors":"Yilmaz Polat, Hasan Baki, Altinsoy Altinsoy, Hi Hi, lal Polat, B. Kanat, Seli Seli, M. Sozen, Mehmet Dal","doi":"10.5455/aces.20150508103342","DOIUrl":"https://doi.org/10.5455/aces.20150508103342","url":null,"abstract":"Intrathoracic goiters are defined as the extension of the thyroid gland into the mediastinum. Superior Vena Cava (SVC) syndrome due to the compression of major vessels can be seen in these patients. Most cases of SVC syndrome occur as a complication of malignancy. A 75-year-old female, non-smoker, was admitted with complaints of the midline neck swell ing for the past 45 years, mild puffiness of face, breathlessness on lying down and dry cough for last 5 years. On clinical examination, there was a massive grade IV thyromegaly. Neck computed tomography revealed a heterogeneous, hyper -trophic, nodular thyroid gland with multiple calcification and mediastinal extension with narrowed trachea. Intraoperatively, there was a huge retrosternal thyroid gland compression of the right brachiocephalic vein, the brachiocephalic trunk from behind the vessel and the right carotid artery along with the right internal jugular vein. Pathological examination showed a nodular colloid goitre without signs of malignancy. When SVC syndrome is secondary to benign thyroid disease, total thyroidectomy should be performed. Abstract Objective: To evaluate the changes in the number of Langerhans Cells (LC) observed in the epithelium of smokeless tobacco (SLT-induced) lesions. Methods: Microscopic sections from biopsies carried out in the buccal mucosa of twenty patients, who were chronic users of smokeless tobacco (SLT), were utilized. For the control group, twenty non-SLT users of SLT with normal mucosa were selected. Th e sections were studied with routine coloring and were immunostained for S-100, CD1a, Ki-67 and p63. Th ese data were statistically analyzed by the Student’s t-test to investigate the di ff erences in the expression of immune markers in normal mucosa and in SLT-induced leukoplakia lesions. Results: Th ere was a signi fi cant di ff erence in the immunolabeling of all markers between normal mucosa and SLT-induced lesions (p<0.001). Th e leukoplakia lesions in chronic SLT users demonstrated a signi fi cant increase in the number of Langerhans cells and in the absence of epithelial dysplasia. Conclusion: Th e increase in the number of these cells represents the initial stage of leukoplakia.","PeriodicalId":30641,"journal":{"name":"Archives of Clinical and Experimental Surgery","volume":"5 1","pages":"242-245"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70764505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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