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POTENSI ANTIMIKROBA EKSTRAK DAUN JAMBLANG (Syzygium cumini L.) DARI KAWASAN GEOTHERMAL IE SEUM ACEH BESAR
Pub Date : 2022-05-29 DOI: 10.36387/jifi.v5i1.915
Munira Munira, Noni Zakiah, Rini Handayani, Muhammad Nasir
Jamblang leaf (Syzygium cumini L.) contains several antimicrobial compounds. The content of chemical compounds in a plant is influenced by environmental factors. The Geothermal area of Ie Seum Aceh Besar has a different temperature and pH of the soil. This research was conducted to determine the antimicrobial activity of jamblang leaf ethanol extract which grew inside and outside the geothermal area. This research is experimental laboratories using a complete randomized design (RAL). The study consisted of 3 treatments, namely distilled water, jamblang leaf extract which grew in the Geothermal area of Ie Seum (EDJDKG) and jamblang leaf extract that grew outside the Geothermal area of Ie Seum (EDJLKG) and each 5 replications. The results showed that jamblang leaf ethanol extract that grew inside and outside the geothermal area of Ie Seum was very influential (p = 0,000) in inhibiting the growth of Staphylococcus aureus, Escherichia coli and Candida albican. Duncan's further test results showed that the largest average inhibitory diameter was produced by EDJDKG (19.20 mm) and was not significantly different from EDJLKG (18.00 mm) in inhibiting the growth of S. aureus. As for E. coli EDJDKG of 20.70 mm and significantly different from EDJLKG (18.70 mm).
Jamblang叶(Syzygium cumini L.)含有多种抗菌成分。植物中化合物的含量受环境因素的影响。Seum Aceh Besar的地热地区具有不同的温度和土壤pH值。对地热区内外生长的腐竹叶乙醇提取物的抑菌活性进行了研究。本研究采用完全随机设计(RAL)的实验实验室。试验分为蒸馏水处理、生长在地热区的jamblang叶提取物(EDJDKG)和生长在地热区以外的jamblang叶提取物(EDJLKG) 3个处理,每5个重复。结果表明,生长在地热区内外的混香叶乙醇提取物对金黄色葡萄球菌、大肠杆菌和白色念珠菌的生长有很好的抑制作用(p = 0000)。Duncan进一步的实验结果表明,EDJDKG产生的平均抑制直径最大(19.20 mm),在抑制金黄色葡萄球菌生长方面与EDJLKG (18.00 mm)没有显著差异。大肠杆菌EDJDKG为20.70 mm,与EDJLKG (18.70 mm)差异显著。
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引用次数: 2
FORMULASI SEDIAAN SIRUP SARI BUAH SENGGANI (Melastoma malabathricum L.)
Pub Date : 2022-05-29 DOI: 10.36387/jifi.v5i1.914
Tri Yanuarto, Devi Novia, Septi Putri Lestari
Senggani fruit (Melastoma malabathricum L.) is one of the wild plants whose leaves are usually used by the community as a medicine for wounds and cancer sores. Senggani fruit contains high anthocyanins and antioxidants, which are very good for preventing cancer in the body. The purpose of this research is to make syrup of Senggani fruit juice. The formulation of Senggani fruit juice syrup was made by heating method at 54°C with various concentrations of F0, F1 (5%), F2 (6%) and F3 (8%). Then, the physical properties were tested, namely organoleptic, viscosity test, pH test, homogenity test, hedonic test and descriptive test. From testing the physical properties of the syrup formulation of Senggani fruit, it was found that the organoleptic test of F2 and F3 showed a change in consistency; for the pH test results the four formulas ranged from 3.98 to 7.07; the homogeneity test on F2 and F3 was not homogeneous, there were black grains at the 3rd week; then the viscosity test of syrup preparations F2 and F3 obtained an average result of 30 - 51.33 cPs; as well as hedonic and descriptive tests with the criteria of somewhat like - like the most preferred is F3.
桑加尼果(Melastoma malabathicum L.)是一种野生植物,其叶子通常被社区用作伤口和癌症溃疡的药物。桑加尼水果含有较高的花青素和抗氧化剂,对预防体内癌症非常有益。本研究的目的是制作桑甘尼果汁糖浆。以不同浓度的F0、F1(5%)、F2(6%)和F3(8%)为原料,在54℃下加温法制备桑甘尼果汁糖浆配方。然后进行物理性能测试,即感官测试、粘度测试、pH测试、均匀性测试、享乐性测试和描述性测试。通过对桑甘尼果糖浆配方的物理性能测试,发现F2和F3的感官测试显示稠度发生了变化;4种配方的pH值为3.98 ~ 7.07;F2和F3的同质性检验不均匀,第3周出现黑色颗粒;然后对糖浆制剂F2和F3进行粘度测试,平均结果为30 ~ 51.33 cPs;以及享乐和描述性测试,标准是有点像,最喜欢的是F3。
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引用次数: 0
OBSERVASI PENGKAJIAN KELENGKAPAN RESEP OBAT BATUK SECARA ADMINISTRATIF DAN FARMASETIK PADA PUSKESMAS CILAMAYA DI KABUPATEN KARAWANG
Pub Date : 2022-05-29 DOI: 10.36387/jifi.v5i1.905
Caroline Noer Asy'ary
An incomplete prescription has the potential to be one of the causes of medication errors. This incident can be avoided by conducting prescription screening by pharmacists which includes a review of administrative and pharmaceutical aspects. The purpose of this study was to determine the administrative and pharmaceutical completeness of prescriptions for the period January – May 2021 at the Cilamaya Health Center in Karawang Regency. The research method is descriptive quantitative with retrospective data collection. The sampling technique was simple random sampling, and 428 prescription sheets were obtained that met the inclusion criteria. The results showed that the administrative completeness of the prescription consisted of: patient's name 100%, patient age 96%, gender 0%, weight 96%, doctor's name 8%, doctor's initials 43%, prescription date 99%, and room of origin. prescription 76%. Meanwhile, pharmaceutically it consists of: 100% dosage form and strength, 96% drug dosage, 99% drug amount, 100% stability and availability, 96% usage rules and 100% compatibility. It can be concluded that based on Permenkes No. 74 of 2016, prescriptions at the Cilamaya Health Center for the period January – May 2021 are not administratively and pharmaceutically complete.
不完整的处方有可能成为用药错误的原因之一。这一事件可以通过药剂师进行处方筛选来避免,其中包括对行政和药物方面的审查。本研究的目的是确定2021年1月至5月期间卡拉旺县Cilamaya卫生中心处方的行政和药物完整性。研究方法为描述性定量与回顾性资料收集。抽样方法为简单随机抽样,共获得符合纳入标准的处方单428张。结果表明,处方的行政完整性包括:患者姓名100%,患者年龄96%,性别0%,体重96%,医生姓名8%,医生首字母43%,处方日期99%,起始室。处方的76%。药学上由100%的剂型和剂量、96%的给药剂量、99%的给药量、100%的稳定性和利用度、96%的使用规则和100%的配伍性组成。可以得出的结论是,根据2016年第74号法令,Cilamaya卫生中心2021年1月至5月期间的处方在行政和药学上都不完整。
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引用次数: 1
PENGARUH EDUKASI TERHADAP PENGETAHUAN GENERASI MUDA DI MEDIA SOSIAL TERKAIT PERAN ESSENTIAL OIL SEBAGAI UPAYA PREVENTIF COVID-19 教育影响年轻一代的知识在社交媒体上的作用,ESSENTIAL OIL作为预防COVID-19的作用
Pub Date : 2022-05-29 DOI: 10.36387/jifi.v5i1.910
Abd Rahem, Althaf Azhar Nur Fadhilah, Fatimah Azwa
Due to the COVID-19 pandemic, there has been an increase in sales and purchases of essential oils. This trend happens because essential oils are claimed to be beneficial for COVID-19 treatment despite there has been no scientific evidence to support this claim. To discover and increase public knowledge regarding the role of essential oils as an effort to prevent the COVID-19 virus, education was provided through social media. The research method used is a quasi-experimental research method or a quasi-experimental type of one group pretest and posttest design. In this study, the targeted respondents are the young generation aged 18-30 years who live on Java. Respondents answered questions using google form to find out the increase in knowledge of the younger generation before and after providing education regarding the role of essential oils. The instrument used is a google form test before and after presenting education related to the role of essential oils. Based on the research, the majority of the younger generation already knows enough information about essential oils in general.
由于COVID-19大流行,精油的销售和购买有所增加。这一趋势的发生是因为精油据称对治疗COVID-19有益,尽管没有科学证据支持这一说法。为了发现和提高公众对精油在预防COVID-19病毒中的作用的认识,通过社交媒体提供了教育。研究方法采用准实验研究方法或准实验型一组前测后测设计。在这项研究中,目标受访者是年龄在18-30岁的年轻一代,他们生活在爪哇。受访者使用谷歌表格回答问题,以了解提供精油作用教育前后年轻一代的知识增长情况。所使用的仪器是谷歌形式的测试,在介绍精油作用的教育之前和之后。根据这项研究,大多数年轻一代已经对精油有了足够的了解。
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引用次数: 0
PERBANDINGAN AKTIVITAS ANTIOKSIDAN PADA MINUMAN INFUSED WATER DARI JERUK NIPIS, JERUK LEMON DAN JERUK KALAMANSI DENGAN METODE DPPH 将从柠檬、柠檬和喀拉曼西橙子中吸收的水的抗氧化剂活性与DPPH方法进行比较
Pub Date : 2022-05-29 DOI: 10.36387/jifi.v5i1.921
Herlina Herlina, Elly Mulyani
Oranges contain compounds that are eficacious as antioxidants which are great for preventing and counteracting free radicals. The purpose of this research is to determine the value of antioxidant activity of infused water drinks of variety oranges (lemon, lime and calamansi oranges). This research was conducted by making an infused water drink by soaking oranges fruits in cooled water and left overnight in the refrigerator. The antioxidant activity was carried out using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method. The data obtained then calculated the value of antioxidant activity and calculated the IC50 value. The results showed that infused water drinks from lemon, lime and calamansi oranges had very strong antioxidant activity seen from the IC50 values which was less than 50 ppm, where calamansi with antioxidant activity value of 28,92 ppm, then followed by lemon with antioxidant activity value of 27.46 ppm and finally lime with antioxidant activity value of 24,39 ppm.
橙子含有有效的抗氧化剂化合物,对预防和对抗自由基很有帮助。本研究的目的是测定各种橙子(柠檬、酸橙和菖蒲橙)泡水饮料的抗氧化活性。这项研究是通过将橙子浸泡在冷水中并在冰箱里过夜来制作一种注入水的饮料来进行的。采用DPPH(1,1-二苯基-2-苦味酰肼)法测定其抗氧化活性。根据所得数据计算抗氧化活性值,并计算IC50值。结果表明,柠檬、酸橙和菖蒲橙冲泡水饮料的IC50值均小于50 ppm,其中菖蒲橙的抗氧化活性值为28、92 ppm,其次是柠檬的抗氧化活性值为27.46 ppm,最后是石灰的抗氧化活性值为24、39 ppm。
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引用次数: 0
PENETAPAN KADAR FLAVONOID TOTAL DAN NILAI SUN PROTECTION FACTOR (SPF) DARI EKSTRAK KERING DAUN CEMPEDAK (Artocarpus integer)
Pub Date : 2022-05-29 DOI: 10.36387/jifi.v5i1.868
Muhammad Ikhwan Rizki, Syifa Auliani, A. Khairunisa, fadlilaturrahman fadlilaturrahman, normaedah normaedah
Ultraviolet rays cause wrinkles and premature ageing. The bad effects of sun exposure can be avoided by using sunscreen. Artocarpus integer is empirically used as a black spot remover and cold powder. Total flavonoid content is an extract quality parameter that is related to the consistency of the pharmacological effects produced. The purpose of this study was to determine the total flavonoid content and the value of Sun Protection Factor (SPF) from the dried extract Artocarpus integer. The study began with a drying of fresh leaves using an oven, making simplicia powder, extraction process by maceration, and drying extracts using a drying cabinet. The dry extract was measured for total flavonoid content using a spectrophotometer UV-Vis with quercetin as a marker. The dry extract also determined the SPF value at concentrations of 200, 400, 600, 800, and 1000 ppm. The results showed that the total flavonoid content of the dry extract of cempedak leaves was 1,283 ± 0.032 %w/w equivalent to quercetin. The SPF value of dry extract of cempedak leaves at concentrations of 200, 400, 600, 800, and 1000 ppm respectively, namely 2,923 ± 0.009, 5.990 ± 0.002, 8.846 ± 0.001, 13,181 ± 0.008 and 15.856 ± 0.1533
紫外线会导致皱纹和早衰。使用防晒霜可以避免阳光照射的不良影响。鹿角果是一种经验上常用的祛斑剂和凉粉。总黄酮含量是提取物的质量参数,关系到其药理作用的一致性。本研究的目的是测定小檗干燥提取物的总黄酮含量和防晒系数(SPF)。研究开始于用烘箱干燥新鲜的叶子,制作简单的粉末,通过浸渍提取过程,并使用干燥柜干燥提取物。以槲皮素为标记物,用紫外可见分光光度计测定干提取物的总黄酮含量。干提取物还测定了200、400、600、800和1000 ppm浓度下的SPF值。结果表明,香柏叶干提取物的总黄酮含量为槲皮素的1283±0.032% w/w。在浓度分别为200、400、600、800和1000 ppm时,香柏叶干提取物的SPF值分别为2923±0.009、5.990±0.002、8.846±0.001、13181±0.008和15.856±0.1533
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引用次数: 1
KESESUAIAN PENYIMPANAN PERBEKALAN FARMASI DI GUDANG INSTALASI FARMASI RUMAH SAKIT ISLAM BANJARMASIN
Pub Date : 2022-05-29 DOI: 10.36387/jifi.v5i1.890
Amaliyah Wahyuni, Raihana Raihana, A. Amalia
Storage of supplies of one of the components of supplies in the hospital. Storage of supplies such as medicines, medical devices and consumable medical materials in the Hospital Pharmacy Installation Warehouse (IFRS) should be highly considered because not all medicines, medical devices and consumable medical materials are treated equally in their storage, ensuring properly maintained. Improper pharmaceutical supplies can result in rapid damage and expiry. The purpose of this study is to determine the percentage of suitability of pharmaceutical supply storage in the Pharmacy Installation Warehouse of Banjarmasin Islam Hospital. Non-experimental research is observation using observation sheet based on the suitability of Permenkes No.72 Year 2016 and SPO RS Islam. The population is Islam IFRS Warehouse and the sample is Islam Hospital Pharmacy Installation Warehouse using saturated sampling method. The result of the percentage of suitability of pharmaceutical supplies storage in the Pharmacy Installation Warehouse of The Islam Hospital Banjarmasin. The results of the conformity permenkes No. 72 Year 2016; pharmaceutical preparations 309 indicators (71.52%); MD 136 indicators (62.96%); and CM 133 indicators (61.57%). Conformity Results Based on SOP Islam Banjarmasin Hospital Year 2018 namely; Pharmaceutical Preparations 244 indicators (72.62%);, and MD 167 indicators (69.58%) and CMM 166 indicators (69.16%).
在医院储存供应品的一个组成部分。应高度考虑在医院药房安装仓库(国际财务报告准则)中储存药品、医疗器械和医用耗材等用品,因为并非所有药品、医疗器械和医用耗材在储存中都得到平等对待,确保得到适当维护。不适当的药品供应可导致迅速损坏和过期。本研究的目的是确定Banjarmasin Islam医院药房安装仓库中药品供应储存的适宜性百分比。非实验研究是基于Permenkes No.72 Year 2016和SPO RS Islam适宜性的观测单进行观测。人口为伊斯兰国际财务报告准则仓库,样本为伊斯兰医院药房安装仓库,采用饱和抽样方法。Banjarmasin伊斯兰医院药房安装仓库储存药品供应品的适宜性百分比结果。2016年第72号符合性文件结果;药物制剂309项指标(占71.52%);MD 136项指标(62.96%);CM 133指标占61.57%。基于SOP的伊斯兰班加马辛医院2018年符合性结果制剂指标244项(占72.62%),MD 167项(占69.58%),中药166项(占69.16%)。
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引用次数: 0
PROFIL PERESEPAN PENGGUNAAN ANTIHIPERTENSI PADA PASIEN RAWAT JALAN DI PUSKESMAS SUNGAI ULIN PERIODE OKTOBER 2020 2020年10月,ULIN river PUSKESMAS门诊采用抗高血压药物的资料
Pub Date : 2022-05-29 DOI: 10.36387/jifi.v5i1.913
Amalia Risna, Jauhar Latifah, Linda Permata Sari, Ronalisa Ronalisa, Henny Maryani, Difa Intannia
Hypertension is a disease that often causes death because many people do not realize it. People have hypertension if the blood pressure above 140/90 mmHg after regular checking. In Sungai Ulin Public health center, hypertension is the second-highest disease. The study aimed to determine the characteristics of hypertensive patients and the profile of prescribing the use of anti-hypertensive drugs in outpatients in the period October 2020 at Sungai Ulin Public health center. This research is an observational descriptive study using retrospective data with the inclusion criteria. A population of all prescription anti-hypertensive drugs given to outpatients in the period October 2020 in Sungai Ulin Public health center (87 prescriptions). The results showed the percentage of prescription use of anti-hypertensive drugs, namely women who received more anti-hypertensive prescriptions as many as 59 (65,02%) prescriptions, while the age criteria from > 65 years was (26,43%). The majority of drugs were given in Puskesmas Sungai Ulin was amlodipine with a percentage of 72,41%.
高血压是一种经常导致死亡的疾病,因为许多人没有意识到这一点。定期检查血压超过140/90 mmHg即为高血压。在双溪乌林公共保健中心,高血压是第二高的疾病。该研究旨在确定2020年10月期间Sungai Ulin公共卫生中心门诊高血压患者的特征和抗高血压药物的处方使用概况。本研究是一项观察性描述性研究,采用具有纳入标准的回顾性数据。2020年10月期间在Sungai Ulin公共卫生中心向门诊患者提供的所有抗高血压药物处方(87张处方)的人口。结果显示,处方使用降压药的比例,即女性服用降压药较多的比例高达59张(65.02%),年龄标准为> 65岁(26.43%)。Puskesmas Sungai用药最多的药物是氨氯地平,占72.41%。
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引用次数: 1
PROFIL PENGGUNAAN OBAT PADA PASIEN COVID-19 DI SALAH SATU RUMAH SAKIT DI BANJARMASIN 在BANJARMASIN的一家医院,COVID-19患者的药物使用情况
Pub Date : 2022-05-29 DOI: 10.36387/jifi.v5i1.917
Yusrinie Wasiaturrahmah, Aditya Maulana Perdana Putra, Nahdha Nahdha, N. Rahmah
Coronavirus 19, Knowing as COVID-19, is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 treatment is still limited to supportive and oxygen therapy. The use of drugs is on the complaints felt by patients and comorbidities. This study aims to look at drug use profiles in COVID-19 patients. This research was included in descriptive research with a retrospective cross-sectional design. This research data was the entire prescription sheet and medical records of COVID-19 patients for March-August 2020 that meet the inclusion criteria. The result from collecting COVID-19 patient data for March-August 2020 obtained 114 medical records that met the criteria for research inclusion. Research Result: Characteristics of study subjects of the male sex are more infected with COVID-19. The age range with the highest number of COVID-19 patients was 46-55 years. Treatment profiles often used in COVID-19 patients are Supplements and Vitamins for 6538 prescriptions and Antibiotics for 2813 prescriptions. The most prescribed supplements and vitamins are Vitamin C, Lakto B, Zinc, and Vitamin C. The most prescribed antibiotics are Azithromycin, Meropenem, and Levofloxacin. The conclusion obtained in this study is that Supplements and vitamins, and Antibiotics are the most prescribed drug class.
冠状病毒19 (COVID-19)是一种由严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)引起的疾病。COVID-19的治疗仍然局限于支持和氧气治疗。药物的使用取决于患者的抱怨和合并症。这项研究旨在研究COVID-19患者的药物使用情况。本研究纳入回顾性横断面设计的描述性研究。本研究数据为符合纳入标准的2020年3月至8月2019冠状病毒病患者的全部处方和病历。通过收集2020年3月至8月的COVID-19患者数据,获得了114份符合研究纳入标准的病历。研究结果:研究对象的特点是男性感染COVID-19较多。新冠肺炎患者人数最多的年龄段为46-55岁。COVID-19患者经常使用的治疗方案是6538张处方的补充剂和维生素,2813张处方的抗生素。处方最多的补品和维生素是维生素C、维生素B、锌和维生素C。处方最多的抗生素是阿奇霉素、美罗培南和左氧氟沙星。本研究得出的结论是,补品和维生素、抗生素是处方最多的药物类别。
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引用次数: 2
EVALUASI PROSEDUR PENYIMPANAN DAN PENDISTRIBUSIAN SEDIAAN FARMASI DAN BAHAN MEDIS HABIS PAKAI DI PUSKESMAS PEKAUMAN BANJARMASIN 药物储存和配送的评估程序已被应用于班雅尔马辛州
Pub Date : 2022-05-29 DOI: 10.36387/jifi.v5i1.927
Noor Aisyah, E. Kumalasari, Merina Hariani, Rina Feteriyani
Storage and distribution are management activities of pharmaceutical preparations and medical consumables in storing and distributing to pharmaceutical service sub-units to avoid expired date. The purpose of this study was to determine the procedure and the percentage of suitability of storage and distribution of pharmaceutical preparations and medical consumables at Banjarmasin's Pekauman Health Center. This type of research is non - experimental with descriptive observative. Data collection using the prospective method. The population in this study is the room and all data storage and distribution of pharmaceutical preparations and medical consumables, with saturated sampling period March-April 2020. The research data was observed for qualitative results and calculated by percentage analysis for quantitative results. The results showed that the storage procedures for pharmaceutical preparations and BMHP were 90% in accordance with the Technical Guidebook for Pharmaceutical Service Standards in Puskesmas and 86.11% in accordance with the Checklist for Quality Assurance of Pharmaceutical Services in Basic Health Services. And the procedures for distributing pharmaceutical preparations and medical consumables at the Banjarmasin Pekauman Health Center 100% in accordance with the Technical Guide to Pharmaceutical Services Standards at the Health Center and the Quality Assurance Checklist for Pharmaceutical Services in Basic Health Services.
储销是医药制剂和医用耗材储销到医药服务分单位,避免过期的管理活动。这项研究的目的是确定Banjarmasin Pekauman保健中心的药物制剂和医疗消耗品的储存和分发程序和适宜性百分比。这种类型的研究是非实验性的描述性观察性研究。采用前瞻性方法收集数据。本研究的人群为药品制剂和医用耗材的房间和所有数据存储和分发,饱和采样期为2020年3月- 4月。定性结果采用观察法,定量结果采用百分比分析法计算。结果表明,药品制剂和BMHP的储存程序符合《普斯克斯马斯市药品服务标准技术指南》的比例为90%,符合《基本卫生服务药品服务质量保证清单》的比例为86.11%。在Banjarmasin Pekauman保健中心分发药物制剂和医疗耗材的程序100%按照《保健中心药品服务标准技术指南》和《基本卫生服务药品服务质量保证清单》执行。
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引用次数: 0
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Jurnal Insan Farmasi Indonesia
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