International Journal of Surgery and Medicine最新文献

{"title":"Investigation of mid-term functional skills and psychological factors in female patients undergoing total knee arthroplasty","authors":"Ahmet Serhat Genç, Nizamettin Güzel, Mahmut Yaran, Anıl Agar, İ. Eseoğlu, Berna Anıl, Esra Korkmaz, Enes Akdemir, Gözde Kesikbaş, A. Yılmaz, L. Kehribar","doi":"10.28982/josam.7876","DOIUrl":"https://doi.org/10.28982/josam.7876","url":null,"abstract":"Background/Aim: Previous studies have yielded conflicting clinical, psychological, and functional outcomes in patients undergoing total knee arthroplasty (TKA). This study aimed to more precisely evaluate the clinical outcomes, mid-term general physical and psychological health status, functional abilities, and improvements in patients’ quality-of-life undergoing TKA.\u0000Methods: This cross-sectional study included 25 female patients older than 55 years who underwent unilateral TKA due to osteoarthritis (OA). The Five Repetition Sit-to-Stand Test (5STS), Stair-Climbing Test (SCT), 6-Minute Walking Test (6MWT), Berg Balance Scale (BBS), Tampa Scale for Kinesiophobia (TSK), and Short Form Health Survey (SF-12) scores of the patients were evaluated using means. Meanwhile, the Lower Limb Length (LLL), Navicular Drop Test (NDT), Proprioception Assessment, Foot Posture Index (FPI-6), Foot Function Index (FFI), Lower Extremity Functional Scale (LEFS), Knee Injury and Osteoarthritis Outcome Score (KOOS), and Oxford Knee Score (OKS) were evaluated by comparing the operated (OP) sides that underwent TKA with the non-operated (NONOP) sides diagnosed with OA.\u0000Results: The study found that LLL (P=0.001), abduction/adduction forefoot on rearfoot (ABD) (P=0.017), and T.FPI-6 (P=0.014) in the FPI-6 parameters, as well as KOOS (P<0.001), OKS (P<0.001), LEFS (P<0.001), and FFI (P<0.001) results, were significantly in favor of the OP limb. Besides some parameters in FPI-6, no significant difference was found between the OP and NONOP extremities in terms of prone and supine proprioception values (P>0.05).\u0000Conclusion: Overall, it was found that TKA plays a crucial role in recovery and regaining functional skills. Including preoperative evaluations with a control group and patients of both sexes in future studies and examining the relationships between the conducted tests and scales may contribute to better evaluating the results.","PeriodicalId":30878,"journal":{"name":"International Journal of Surgery and Medicine","volume":"114 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77790089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of obesity on autologous bone marrow transplant and post-transplant outcomes","authors":"S. Sadri, Cem İdrisoğlu, Y. Mutlu, A. Gemici, H. Bekoz, O. Sevindik, Fatma Deniz Sargin","doi":"10.28982/josam.7664","DOIUrl":"https://doi.org/10.28982/josam.7664","url":null,"abstract":"Background/Aim: Autologous hematopoietic cell transplantation (AutoHCT), administered at high doses, has improved survival rates among patients with refractory or recurrent lymphoma and multiple myeloma (MM). However, inconsistencies in defining obesity, varying body weight ranges, and heterogeneous patient populations have been examined. Some researchers have hypothesized that significantly overweight patients face a higher risk of transplant-related complications. This study investigates the association between body mass index (BMI), obesity, and autologous peripheral stem cell mobilization.\u0000Methods: A retrospective evaluation of data from 180 patients who underwent peripheral stem cell mobilization at our clinic between 2014 and 2020 was conducted. Excluding patients under 18 years of age, the primary objective was to assess how BMI influences autologous transplant outcomes and mortality. This retrospective cohort study aimed to determine whether obesity constitutes an independent risk factor for autologous bone marrow transplantation.\u0000Results: Among the patients, the most prevalent diagnosis (47.2%) was MM, with notable differences in incidence rates across BMI categories (P=0.039). Obesity and overweight were associated with a higher incidence of MM (47.2%), whereas normal and underweight individuals had predominantly been diagnosed with DLBCL (44.2%). Significant differences in CD34 cell counts were observed among BMI groups (P=0.033). Overweight and obese individuals exhibited lower CD34 cell counts than underweight/normal groups (P=0.033). The treatment group showed significantly higher CD34 cell counts than the G-CSF alone group (P=0.046). Female gender (P=0.022), PLT engraftment (P=0.024), post-chemo-mobilization hospital-stay duration (P=0.019), and G-CSF count were identified as mortality risk factors (P=0.017).\u0000Conclusions: This investigation found no adverse correlation between mortality and weight among patients with various hematological malignancies undergoing AutoHCT. Obesity alone should not be a contraindication for proceeding with AutoHCT in clinically warranted hematological malignancy treatment, as no significant survival differences were observed among overweight, obese, and normal-weight individuals.","PeriodicalId":30878,"journal":{"name":"International Journal of Surgery and Medicine","volume":"116 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86214811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of macrocytosis on erlotinib response in metastatic non-small cell lung cancer","authors":"S. Kazaz, M. Duygulu","doi":"10.28982/josam.7930","DOIUrl":"https://doi.org/10.28982/josam.7930","url":null,"abstract":"Background/Aim: Numerous studies have assessed the relationship between macrocytosis and responses to chemotherapeutic agents and TKIs such as sunitinib and imatinib. However, there is limited data in the literature regarding the prognostic or predictive value of macrocytosis in using erlotinib. If a relationship is detected, early response/resistance assessment can be performed before imaging time in the follow-up of treatments, and a more cost-effective, non-invasive method can be employed for response monitoring. This study aimed to elucidate the effect of macrocytosis on response rates in patients treated with erlotinib for non-small cell lung cancer.\u0000Methods: Seventy-five individuals diagnosed with non-small cell lung cancer (NSCLC) and admitted to our institution were enrolled in this retrospective cohort study. Baseline demographics, time of diagnosis, previous treatment, and the initiation or cessation of erlotinib were recorded. Data of patients with and without macrocytosis were analyzed. Stable disease, partial and complete response rates, and progressive disease response were evaluated separately as response rates. Progression-free survival between drug initiation and discontinuation due to progression was interpreted using Kaplan-Meier curves.\u0000Results: The distribution of the overall survival (OS) and progression-free survival (PFS) evaluations revealed that 84% (n=63) of the patients were deceased, and the progression rate was 94.7% (n=71). The median OS of the patients was 18 months, and the median PFS was 11 months. There was a statistically significant difference in overall survival in females, with a median OS of 25 months (95% CI 17–32 months) and a median OS of 13 months in males (95% CI 9–20 months) (P=0.008). PFS was 14.5 months (95% CI 11–21 months) in women and six months (95% CI 4–17 months) in men, and there was a statistically significant difference (P=0.02). A statistically significant difference was achieved between MCV values measured during diagnosis and the third month between age groups (P=0.044).\u0000Conclusion: The outcomes of this research suggest a statistically significant difference between the MCV values measured at the time of diagnosis and the third month regarding age groups. Both OS and PFS in women were statistically significantly higher than in men.","PeriodicalId":30878,"journal":{"name":"International Journal of Surgery and Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90495631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predisposal factors leading to early re-amputation among diabetic patients who underwent minor amputation","authors":"Onur Gürsan, Mustafa Çeltik, Cihangir Türemiş","doi":"10.28982/josam.7933","DOIUrl":"https://doi.org/10.28982/josam.7933","url":null,"abstract":"Background/Aim: Prolonged wound complications and the possibility of reoperations are significant outcomes following minor amputations. As time progresses after the initial surgery, re-amputations become more prevalent. Contrary to prevailing beliefs, the incidence of early amputations remains consistent. Additionally, it is widely acknowledged that the first 6 months following the initial surgery pose the highest risk period for reoperation. This retrospective clinical study aims to investigate the risk factors contributing to ipsilateral re-amputation procedures within 6 months of the initial minor amputation.\u0000Methods: A retrospective cohort study was conducted involving amputee patients from 2008 to 2020. Patients with traumatic events, musculoskeletal tumors, prior major amputations, and those who underwent soft tissue procedures such as debridement, incision, drainage, or secondary closure were excluded. Patients who had undergone preoperative lower limb arterial Doppler ultrasound and whose initial preoperative laboratory records were accessible were included. The total cohort comprised 168 patients, comprising 57 women and 109 men. The mean follow-up duration was 1.5 years (range: 1.1–3.2 years). Patients who underwent ipsilateral re-amputation were categorized into two groups based on the timing of the subsequent surgery. The first group comprised 110 (65.5%) patients who underwent ipsilateral re-amputation 6 months after the initial amputation, while the second group encompassed 58 (34.5%) patients who underwent ipsilateral re-amputation within 6 months of the initial amputation.\u0000Results: Among the 168 patients, 58 (34.5%) experienced ipsilateral re-amputation within 6 months of their initial minor amputations, while 64.5% underwent re-amputation surgery after the initial 6 months. The absence of peripheral arterial disease was not linked to early re-amputations (P=0.001). Although the mean C-reactive protein values (80.30 mg/dL and 84.26 mg/dL for groups 1 and 2, respectively) did not display significance between the groups (P=0.40), the group undergoing amputation within 6 months demonstrated significance with elevated serum white blood cell mean levels (10.44 mcL and 11.96 mcL for groups 1 and 2, respectively; [P=0.004]). Moreover, lower hemoglobin levels (11.41 g/dL and 10.77 g/dL for groups 1 and 2, respectively) were associated with re-amputation within the initial 6 months following the initial surgery (P=0.024).\u0000Conclusion: The study underscores that the incidence of re-amputation after minor amputations in diabetic patients is comparably high, as has been reported in recent literature. While the selection of the initial amputation level remains pivotal, and not all patient-specific factors were examined in this study, the research brings attention to specific laboratory values and the vascular status of the diabetic limb as crucial considerations for surgeons prior to the initial surgery.","PeriodicalId":30878,"journal":{"name":"International Journal of Surgery and Medicine","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75410070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"25-hydroxy vitamin D levels in patients with myelofibrosis and potential relationships with disease severity: A case-control study","authors":"Y. Ipek","doi":"10.28982/josam.7923","DOIUrl":"https://doi.org/10.28982/josam.7923","url":null,"abstract":"Background/Aim: Although vitamin D deficiency has been associated with cancer and its prognosis, data is unclear regarding associations with myelofibrosis. This study aimed to measure 25-hydroxy vitamin D levels in patients with myelofibrosis and to evaluate its relationship with prognoses.\u0000Methods: This case-control study consisted of 72 patients with myelofibrosis and 75 controls. The Dynamic International Prognostic Scoring System was used to determine prognostic risk groups, and patients were divided into two subgroups: intermediate-1 (low risk) and intermediate-2 (high risk).\u0000Results: The median 25-OHD levels were decreased in the myelofibrosis group more so than in the controls (13.05 vs. 23.0 ng/mL, P<0.001). A cut-off value of ≤ 16.5 ng/mL yielded a sensitivity of 84.72% and a specificity of 80% for the identification of patients with myelofibrosis. This impact was also evident when adjusted for age and sex, showing that patients with low 25-hydroxy vitamin D (≤16.5) had a 23.787-fold higher probability to have myelofibrosis (OR: 23.787, 95% CI: 9.676-58.479, P<0.001). When examined for the two prognostic subgroups, 25-hydroxy vitamin D was found to be significantly lower in the intermediate-2 and high subgroup (P=0.017). For a cut-off value of ≤13.7 ng/mL, 25-hydroxy vitamin D level was able to discriminate patients in the intermediate-2 and high subgroup from those with lower risk (sensitivity: 77.8%, specificity: 55.6%).\u0000Conclusion: A serum 25-hydroxy vitamin D level may serve as a biomarker associated with myelofibrosis diagnosis and prognosis; however, the discriminatory value for prognostic groups was low, indicating the need for larger and longitudinally-designed studies.","PeriodicalId":30878,"journal":{"name":"International Journal of Surgery and Medicine","volume":"397 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74311497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aortic arch repair with extended end-to-side anastomosis in neonates and infants with transverse arch hypoplasia","authors":"Onur Doyurgan, Hasan Balık","doi":"10.28982/josam.7905","DOIUrl":"https://doi.org/10.28982/josam.7905","url":null,"abstract":"Background/Aim: The use of patches to repair the aortic arch is believed to have a positive effect on long-term morbidity. In this study, perioperative and follow-up data of patients who underwent transverse arch repair with a patch were compared with the data of patients who underwent end-to-end anastomosis (ESA).\u0000Methods: In this retrospective cohort study, the data of 27 patients (including 18 newborns) who underwent aortic arch repair at the Gazi Yasargil Education and Research Hospital between January 2018 and April 2023 were analyzed. The inclusion criteria included a diagnosis of proximal and distal transverse aortic arch hypoplasia, an age younger than 12 months of age, and the completion of aortic arch repair using cardiopulmonary bypass. Patients who underwent recoarctation repair due to residual obstruction, patients with single ventricular physiology, and patients who underwent aortic arch repair via a lateral thoracotomy without undergoing cardiopulmonary bypass were excluded from the study. The patients were divided into two groups. Group 1 included individuals who underwent aortic anterior wall expansion with autologous pericardium in addition to ESA; Group 2 included patients who underwent ESA only.\u0000Results: The median age of the patients was 21 days (range: 6–365 days), and the median body weight of the cohort was 3.5 kilograms (range: 2.4–8.9 kilograms). Enlargement with autologous pericardial patch was applied to 11 patients (40.7%). Surgical procedures performed in addition to arch repair included eight ventricular septal defect closures, six instances of pulmonary banding, three atrial septal defect closures, and one subvalvular pulmonary stenosis repair. The in-hospital mortality rate was 11.1% (n=3). Those three patients died due to sepsis. The median follow-up period was 152 days (range: 10–1316 days). Recoarctation requiring re-intervention did not occur in any of the studied patients. The antegrade selective cerebral perfusion time was statistically significantly longer in patients who underwent aortic arch repair using a patch (P=0.03).\u0000Conclusion: Repair of the arch with a patch may contribute to a reduction in long-term mortality and morbidity. However, there is a need for more comprehensive and long-term follow-up studies to verify these findings.","PeriodicalId":30878,"journal":{"name":"International Journal of Surgery and Medicine","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81263966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The etiology, risk factors, and clinical features of anaphylaxis: The single-center retrospective cohort study of the tertiary university hospital","authors":"C. Tunakan Dalgıç","doi":"10.28982/josam.7906","DOIUrl":"https://doi.org/10.28982/josam.7906","url":null,"abstract":"Background/Aim: Anaphylaxis presents in multiple ways, making its diagnosis challenging. Delayed diagnosis can lead to a postponement in administering crucial adrenaline treatment. The prevalence of anaphylaxis varies by geographical region and gender. However, there has been no comprehensive regional analysis of anaphylaxis data within our country. Despite an increasing incidence, our understanding of anaphylaxis etiology, risk factors, and clinical features remains limited, particularly within our nation. This study aims to assess the frequency, etiology, risk factors, and clinical findings of anaphylaxis among patients seen at the allergy clinic of a tertiary university hospital. Additionally, it seeks to compare regional data with existing literature.\u0000Methods: This retrospective cohort study reviewed the medical records of 8,295 patients who visited the allergy outpatient clinic at Sivas Cumhuriyet University Hospital between July 2, 2018, and December 10, 2019. The hospital’s data system retrospectively analyzed records using the ICD code T78.2 (anaphylaxis). Only cases where patients were prescribed an adrenaline auto-injector were included. The study evaluated anaphylaxis frequency, etiologies, demographics, and clinical features.\u0000Results: The study identified 77 patients (n=77) with a mean age of 40.29 (3.77) years, consisting of 47 females and 30 males. The frequency of anaphylaxis among allergy outpatient admissions was less than 1% (0.009%). Single-type atopic diseases included venom allergy (23%), drug allergy (14%), inhalant allergens (n=6), food allergens (n=4), and skin allergic diseases (n=3). Multiple allergic diseases were present in 40% (n=31) of cases. Prick tests were performed on 56 (72%) patients, with 25 (44%) yielding negative results. Among positive prick test cases, venom was the main cause of anaphylaxis (82%), while drug allergy was more prevalent (68.2%) among negative test results (P=0.016). Inhalant allergen sensitivity and allergen polisensitivity did not significantly influence the anaphylaxis cause (P<0.001). Causes of anaphylaxis included drug allergy (47%), venom allergy (31%), food allergens (16%), food-dependent exercise-induced reactions (n=2), idiopathic cases (n=2), and cold urticaria (n=1). Non-steroidal anti-inflammatory drugs (NSAIDs) (44%) and beta-lactams (10%) were the primary culprits. In cases where neither drugs nor venom were involved, food allergies were the cause (P<0.001). With venom allergy, the cause was venom, and without venom, drug allergy was the cause (P<0.001). Female patients showed significantly higher drug- and food-related anaphylaxis rates than males (P=0.032 and P=0.042, respectively). History of Apis mellifera-related anaphylaxis was significantly more common than Vespula vulgaris-related cases (P=0.028). Anaphylaxis severity included grade 2 (30%), grade 3 (48%), and grade 4 (12%) reactions. Recurrent anaphylaxis episodes occurred in 55% (n=42) of patients. Initial hospital ad","PeriodicalId":30878,"journal":{"name":"International Journal of Surgery and Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74201601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Renal dysfunction due to surgical stress and its effects on survival in patients aged 90 and over","authors":"S. Kutlusoy, E. Koca, A. Aydın","doi":"10.28982/josam.7847","DOIUrl":"https://doi.org/10.28982/josam.7847","url":null,"abstract":"Background/Aim: Published studies of surgical outcomes in patients aged 90 years and older have mostly focused on specific surgeries such as hip fractures. Unlike previous reports, our study includes all surgical procedures in patient groups aged 90 and over for eight years in our hospital. We aim to be able to predict the responses of an older adult’s kidney due to surgical stress by using the values of plasma urea and creatine, which are preoperative and postoperative routine laboratory parameters, and to predict its effect on mortality.\u0000Methods: Our study was conducted as a retrospective cohort study with 284 patients whose ages ranged from 90 to 119 and who had undergone a surgical operation. The patients were divided into four groups according to preoperative and postoperative creatinine values: preoperative and postoperative creatinine <1.25 mmol/L RFT-I group; preoperative creatinine <1.25 mmol/L but postoperative creatinine >1.25 mmol/L RFT-II group; preoperative creatinine >1.25 mmol/L but postoperative creatinine <1.25 mmol/L RFT-III group; and preoperative and postoperative creatinine >1.25 mmol/L RFT-IV group.\u0000Results: Of the 284 cases, 62% required intensive care after surgery. While 95.4% of the patients were discharged, 4.6% did not survive. No renal dysfunction was observed in the RFT-I group (68.7%, n=195) (preoperative and postoperative creatinine <1.25 mmol/L). In the RFT-II group (17.6%, n=50), renal dysfunction (creatinine >1.25 mmol/L) developed due to postoperative surgical stress (creatinine <1.25 mmol/L). In patients in the RFT-III group (6%, n=17), preoperative renal dysfunction (creatinine >1.25 mmol/L) improved with postoperative care (creatinine <1.25 mmol/L). In the RFT-IV group (7.7%, n=22), preoperative renal dysfunction (creatinine >1.25 mmol/L) did not improve postoperative renal dysfunction despite appropriate perioperative fluid replacement.\u0000Conclusion: Our study observed an increase in postoperative urea and creatinine values due to surgical stress in our patient group aged 90 and over, who had limited physiological reserves. However, it has been shown that improvement in renal function tests can be achieved with appropriate fluid replacement and postoperative intensive care treatment in patients with postoperative or preoperative renal dysfunction. Our rates of postoperative renal dysfunction due to surgical stress were lower and did not change mortality.","PeriodicalId":30878,"journal":{"name":"International Journal of Surgery and Medicine","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84721759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective cohort analysis of pediatric daycare anesthesia in dentistry: An assessment of postoperative complications","authors":"Seher Orbay Yasli, Dilek Günay Canpolat, Ebru Baydan","doi":"10.28982/josam.7898","DOIUrl":"https://doi.org/10.28982/josam.7898","url":null,"abstract":"Background/Aim: In pediatric populations, the frequent challenges of patient cooperation often necessitate treatments to be performed under general anesthesia. Since these procedures do not fall under the category of major surgery, daycare anesthesia has become a prevalent approach in this field. The advantages of daycare anesthesia, such as reduced hospital stay durations and costs, make it a preferred method. It is well-recognized that daycare anesthesia, when applied across various surgical fields, has unique postoperative complications, which can sometimes be linked to the surgical procedure itself. Dental treatments represent a specific surgical domain, and elucidating potential postoperative complications in this area draws attention to preventive measures and is vital for enhancing postoperative patient comfort. The primary objective of this study was to evaluate and identify the most prevalent postoperative symptoms and complications associated with pediatric dentistry.\u0000Methods: This retrospective cohort study was conducted at the Erciyes University Faculty of Dentistry between January 15 and April 15, 2019. We analyzed records of 245 pediatric patients aged 3 to 13 who underwent day-case dental procedures. The inclusion criteria encompassed all patients who underwent dental procedures under general anesthesia and were classified as ASA 1-2. Variables such as demographic data, procedure duration, comorbidities, and postoperative complications were extracted and analyzed for the current study.\u0000Results: Out of the 245 pediatric patients, the median age was 6.0 years, ranging from 3.0 to 13.0 years. Females comprised 52.7% of the cohort. Most patients (62.9%) were classified under ASA class one. 27.8% of the patients reported postoperative complications such as sore throat, hoarseness, cough, or nausea/vomiting. The most prevalent postoperative complications were hoarseness (11.4%) and sore throat (9.8%). Demographic and clinical characteristics of patients with and without postoperative complications were compared. Gender significantly influences the occurrence of postoperative complications. Males had a rate of 11.0% (27 out of 245), while females had a rate of 16.7% (41 out of 245), with females experiencing complications at a higher rate than males (P=0.01). Age also played a role in complications: the mean age for patients with complications was 6.0 years, compared to 5.0 years for those without complications (P=0.02).\u0000Conclusion: Pediatric daycare anesthesia, especially for dental procedures, has proven effective and safe. However, each child presents a unique set of challenges, and it’s crucial to recognize and mitigate potential risks. By understanding common postoperative symptoms and tailoring anesthesia techniques accordingly, healthcare professionals can optimize outcomes and enhance the quality of pediatric patient care.","PeriodicalId":30878,"journal":{"name":"International Journal of Surgery and Medicine","volume":"53 5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87703860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prognostic effect of lymphocyte, monocyte, and platelet counts, mean platelet volume, neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, and platelet-to-lymphocyte ratio on different stages of pressure ulcers","authors":"L. Delen, Mesut Öterkuş","doi":"10.28982/josam.7829","DOIUrl":"https://doi.org/10.28982/josam.7829","url":null,"abstract":"Background/Aim: Pressure ulcers (PU) pose a significant problem for patients in intensive care. Various factors contribute to the development of pressure sores. The primary focus of treatment is to implement measures that prevent factors such as nutrition and positioning, which can lead to PUs. Therefore, it is crucial to identify parameters that can serve as warning signals for the formation and progression of PU. This study investigates the potential use of hematological parameters as warning signals.\u0000Methods: Demographic data, co-morbidities, PU stages, and laboratory parameters of 158 patients hospitalized in the intensive care unit who developed pressure ulcers during their hospital stay were recorded and analyzed.\u0000Results: Among the 158 cases included in the study, PUs were more prevalent in patients of advanced age, those with pneumonia, chronic obstructive pulmonary disease (COPD), coronary diseases, and neurodegenerative diseases. Mean platelet volume (MPV) was significantly higher in PU stages 2 and 3 compared to stage 1. However, age, lymphocyte count, monocyte count, neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), and platelet-to-lymphocyte ratio (PLR) did not exhibit significant differences among the stages of PU (P<0.05).\u0000Conclusion: Advanced age, pneumonia, COPD, coronary diseases, and neurodegenerative diseases are identified as risk factors for PU. Although MPV was initially considered a potential, stimulating parameter, the evidence was insufficient. Further research is required to explore this issue. The impact of parameters other than MPV did not show any excitatory signal in this study.","PeriodicalId":30878,"journal":{"name":"International Journal of Surgery and Medicine","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79849050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}