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2023 International Conference on Intelligent Supercomputing and BioPharma (ISBP)最新文献

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Adaptive Noise-Reduction Algorithm for Diaphragm Electromyography Based on Linear Prediction 基于线性预测的膈肌电图自适应降噪算法
Pub Date : 2023-01-06 DOI: 10.1109/ISBP57705.2023.10061294
Lingxi Chen, Yuan-da Xu, Bin Li, Hongqiang Mo
Diaphragm electromyography (EMGdi) collected by esophageal electrodes can provide important information for the assessment of the respiratory system. But it is vulnerable to electrocardiogram (ECG) interference. It is pointed out that the autocorrelation function of EMGdi is significantly different from that of ECG. And accordingly, a filter based on linear prediction is proposed to suppress the ECG interference. The coefficients of the filter are adjusted on line so as to adapt to different subjects or the slow change of the autocorrelation function of the same subject over time. The filter is applied to clinically acquired signals, and the results demonstrate that it can effectively suppress the ECG interference, and the filtered EMGdi is in a good synchronization with the transdiaphragmatic pressure (Pdi).
食管电极采集的膈肌电图(EMGdi)可为评估呼吸系统提供重要信息。但它容易受到心电图的干扰。指出EMGdi的自相关功能与心电的自相关功能存在显著差异。在此基础上,提出了一种基于线性预测的滤波器来抑制心电干扰。滤波器的系数在线调整,以适应不同主题或同一主题的自相关函数随时间的缓慢变化。将该滤波器应用于临床采集信号,结果表明该滤波器能有效抑制心电干扰,滤波后的EMGdi与经膈压(Pdi)具有良好的同步性。
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引用次数: 0
Classification and Processing of MIT-BIH Arrhythmia-Based on BP Algorithm 基于BP算法的MIT-BIH心律失常分类与处理
Pub Date : 2023-01-06 DOI: 10.1109/ISBP57705.2023.10061303
Fumin Mi, Baixuan Li, Xiaojie Cheng, Yunjie Zhao, Minyi Li, Jin Jing
ECG recognition is of great significance to the diagnosis of heart diseases. Based on the data of the MIT-BIH Arrhythmia Database, a more accurate ECG signal map was extracted using wavelet transform, a BP neural network was constructed for pattern recognition, and five types of arrhythmia-sinus arrhythmia, premature beats, Yibo, sinoatrial block, and atrial block. And compared with the BP network using SVM and K nearest neighbor algorithm, it is found that the BP network performs better.
心电识别对心脏疾病的诊断具有重要意义。基于MIT-BIH心律失常数据库数据,采用小波变换提取更准确的心电信号图,构建BP神经网络进行模式识别,将心律失常分为窦性心律失常、早搏、易波、窦房传导阻滞、房传导阻滞5种类型。并与使用支持向量机和K近邻算法的BP网络进行比较,发现BP网络的性能更好。
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引用次数: 0
Research on the Application of Artificial Intelligence in the Development of Biomedicine and Oncology 人工智能在生物医学和肿瘤发展中的应用研究
Pub Date : 2023-01-06 DOI: 10.1109/ISBP57705.2023.10061308
Hua-Ru Wang, Yanju Jing
The advent of the era of artificial intelligence (AI) has greatly promoted the integration and development of multi-disciplines, especially in the fields of health care and education. At present, artificial intelligence technology has penetrated into various fields of medicine, through the establishment of data information processing model and its advanced computer software analysis system, to promote the diagnosis of patients, drug discovery and hospital management. To this end, this paper summarizes the technical experimental support of artificial intelligence in drug design, clinical trial design, synthetic biology and tumor, aiming to promote the continuous update and development of AI technology and lead a new era of revolution.
人工智能(AI)时代的到来,极大地促进了多学科的融合与发展,特别是在医疗保健和教育领域。目前,人工智能技术已经渗透到医学的各个领域,通过建立数据信息处理模型及其先进的计算机软件分析系统,促进患者的诊断、药物发现和医院管理。为此,本文总结了人工智能在药物设计、临床试验设计、合成生物学和肿瘤等方面的技术实验支撑,旨在推动人工智能技术的不断更新和发展,引领新时代的革命。
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引用次数: 0
Artificial Intelligence Algorithms in Biomedical Application 人工智能算法在生物医学中的应用
Pub Date : 2023-01-06 DOI: 10.1109/ISBP57705.2023.10061317
Yuehua Song
In recent years, the rapid development of artificial intelligence (AI) has accelerated the development of many social industries. In view of the demand for large data collection and effective medical data processing, AI has undoubtedly become an important part of biomedical research. Medical professionals can accurately diagnose and treat a variety of symptoms in patients with the help of AI algorithms. Modern AI technologies, such as traditional neural networks for structured data and natural language processing for unstructured data, can accurately analyze various medical data. The medical industry uses these AI learning techniques for disease diagnosis, drug discovery, and medical image analysis. Against this backdrop, this paper focuses on the application of AI algorithms in biomedicine and examined cases from biomedical research in addition to the introduction of machine learning, deep learning, and transformer models. Last but not least, we briefly introduce the progress of AI in biomedicine and the difficulties it will encounter.
近年来,人工智能(AI)的快速发展加速了许多社会行业的发展。鉴于对大数据采集和有效医疗数据处理的需求,人工智能无疑已成为生物医学研究的重要组成部分。医疗专业人员可以在人工智能算法的帮助下准确诊断和治疗患者的各种症状。现代人工智能技术,如用于结构化数据的传统神经网络和用于非结构化数据的自然语言处理,可以准确分析各种医疗数据。医疗行业将这些人工智能学习技术用于疾病诊断、药物发现和医学图像分析。在此背景下,本文重点介绍了人工智能算法在生物医学中的应用,并分析了生物医学研究中的案例,同时介绍了机器学习、深度学习和变压器模型。最后,我们简要介绍了人工智能在生物医学领域的研究进展和面临的困难。
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引用次数: 0
Improving Genome Compression Performance by Extending Reference Sequences 通过扩展参考序列提高基因组压缩性能
Pub Date : 2023-01-06 DOI: 10.1109/ISBP57705.2023.10061320
XiangDong Ma, Jianhua Chen
We propose an efficient referential genome compression algorithm called RCCG. It extends reference genomes by its reverse complementation and uses coprime window sampling to detect the maximum matches (MEMs) between two genome sequences. After the assessment, those selected matches will be united to form mutation-containing matches (MCMs). The average compression ratio of the proposed algorithm is higher than that of the state-of-the-art genome compression algorithms.
我们提出了一种高效的参考基因组压缩算法RCCG。它通过反向互补来扩展参考基因组,并利用协素窗采样来检测两个基因组序列之间的最大匹配(MEMs)。经过评估后,这些被选中的匹配将被联合起来形成包含突变的匹配(mcm)。该算法的平均压缩比高于目前最先进的基因组压缩算法。
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引用次数: 0
Building Semantic Segmentation of High-resolution Remote Sensing Image Buildings Based on U-net Network Model Based on Pytorch Framework 基于Pytorch框架的U-net模型的高分辨率遥感影像建筑语义分割
Pub Date : 2023-01-06 DOI: 10.1109/ISBP57705.2023.10061309
Xiaolong Wu
Modern remote sensing technology has developed rapidly in recent years. The high-resolution remote sensing images brought by new technologies have good application prospects in military and civilian fields, but the information contained in them is also richer, which increases the complexity of remote sensing image analysis and understanding. At present, artificial intelligence technology represented by deep learning has been widely used in the field of image processing. This paper adopts the U-net network model and uses the transfer learning method to train on the remote sensing image dataset published by the French National Institute of Information and Automation (Inria) to verify the effectiveness of the deep learning semantic segmentation method on high-resolution remote sensing images. and stability. Experiments show that the model has an accuracy of 86.86% in extracting buildings from images, a recall rate of 82.54%, and an average intersection ratio of 84.53%, which is effective in semantic segmentation of high-resolution remote sensing images.
现代遥感技术近年来发展迅速。新技术带来的高分辨率遥感图像在军事和民用领域具有良好的应用前景,但其中包含的信息也更加丰富,这增加了遥感图像分析和理解的复杂性。目前,以深度学习为代表的人工智能技术已广泛应用于图像处理领域。本文采用U-net网络模型,采用迁移学习方法在法国国家信息与自动化研究所(Inria)公布的遥感图像数据集上进行训练,验证深度学习语义分割方法在高分辨率遥感图像上的有效性。和稳定性。实验表明,该模型在图像中提取建筑物的准确率为86.86%,召回率为82.54%,平均相交率为84.53%,对高分辨率遥感图像的语义分割是有效的。
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引用次数: 0
Pacellation method based on brain cortical morphological aging trajectory in normal cohorts 基于正常人群脑皮层形态老化轨迹的分组方法
Pub Date : 2023-01-06 DOI: 10.1109/ISBP57705.2023.10061316
Jing Xia
The brain goes through various anatomical changes with age. These alterations are a result of ageing naturally. A more profound comprehension of these typical changes is crucial for separating them from pathogenic ones. In this study, we exhibit the ageing trajectories of cortical morphology by using cortical thickness from 55 to 85 years old. To explore the ageing hierarchical pattern, the whole cortex is divided into different regions with similar ageing trajectories. To construct the similarity matrix, we computed Pearson’s correlation coefficient between the cortical thickness of any paired vertices on the cortical surface. Then, we applied the parcellation method based on the similarity matrix on 490 normal middle-aged and old adults from 55 to 85 years old, and achieved meaningful hierarchical parcellation ageing maps based on cortical ageing trajectory. We then fit the ageing trajectory of the cortical thickness in each cluster. The results indicate that the rapid thinning regions in clusters are related to the temporal cortex and prefrontal cortices, while slowly thinning regions in clusters are related to the insula and medial occipital cortices. Importantly, our generated parcellation ageing maps indicate the hierarchical ageing patterns of normal middle-age and old adults, which is essential in disease diagnosing related to neurodegeneration and can help understand the ageing process.
随着年龄的增长,大脑会经历各种解剖学上的变化。这些变化是自然老化的结果。更深刻地理解这些典型变化对于将它们与致病变化区分开来至关重要。在这项研究中,我们通过使用皮质厚度从55岁到85岁来展示皮质形态的衰老轨迹。为了探索衰老的分层模式,将整个皮层划分为具有相似衰老轨迹的不同区域。为了构造相似矩阵,我们计算了皮质表面上任何配对顶点的皮质厚度之间的Pearson相关系数。在此基础上,对490名55 ~ 85岁的正常中老年人进行了相似矩阵分割,得到了有意义的基于皮层衰老轨迹的分层分割衰老图。然后,我们拟合每个簇的皮质厚度的老化轨迹。结果表明,脑簇中快速变薄的区域与颞叶皮层和前额叶皮层有关,而缓慢变薄的区域与脑岛皮层和枕叶内侧皮层有关。重要的是,我们生成的包裹老化图显示了正常中老年人的分层老化模式,这在与神经变性相关的疾病诊断中是必不可少的,可以帮助理解衰老过程。
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引用次数: 0
Fused Residual Attention Dense Double-U Network Retinal Vessel Segmentation Algorithm 融合残差注意密集双u网络视网膜血管分割算法
Pub Date : 2023-01-06 DOI: 10.1109/ISBP57705.2023.10061315
Chunhui Zhu, Xiaowei Niu, Lu Zuo, Ziwei Liu
In view of the slightly low accuracy of the existing overall segmentation algorithm of retinal vessels, a fused residual attention dense convolution double-U network, LSCD-UNet (Laddernet network based on scSE-Residual and CBAM and dense cavity convolution) was proposed.. Laddernet, a form of UNet, was introduced into the network. On this basis, the residual module with shared weights was upgraded and replaced with the scSE-Residual module of shared weights to facilitate feature enhancement extraction. A multi-module was introduced at the bottom of this network, consisting of the Convolutional Attention Mechanism Module (CBAM) and Dense Cavity Convolution Module (DAC) in series to expand the field of view and capture more subtle vascular features. Hybrid loss function was used to accelerate the network convergence. The LSCD-UNet algorithm was validated on the public datasets, DRIVE and STARE,. The results showed that the LSCD-UNet algorithm had an accuracy of 97.35% and 97.28%, a sensitivity of 81.80% and 86.23%, an AUC of 98.82% and 99.02%, and an F1 value of 84.89% and 84.97%, respectively, outperforming UNet and Laddernet and other retinal vessel segmentation algorithms.
针对现有视网膜血管整体分割算法准确率略低的问题,提出了一种融合残差注意密集卷积的双u网络LSCD-UNet(基于scse -残差、CBAM和密集腔卷积的Laddernet网络)。梯子网,UNet的一种形式,被引入到网络中。在此基础上,将共享权值的残差模块升级为共享权值的scse -残差模块,便于特征增强提取。在该网络的底部引入了一个多模块,由卷积注意机制模块(CBAM)和密集腔卷积模块(DAC)串联组成,以扩大视野并捕捉更细微的血管特征。采用混合损失函数加快网络收敛速度。LSCD-UNet算法在DRIVE和STARE两个公共数据集上进行了验证。结果表明,LSCD-UNet算法的准确率分别为97.35%和97.28%,灵敏度分别为81.80%和86.23%,AUC分别为98.82%和99.02%,F1值分别为84.89%和84.97%,优于UNet和Laddernet等视网膜血管分割算法。
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引用次数: 0
Hybrid Multistage Feature Selection Method and its Application in Chinese Medicine 混合多阶段特征选择方法及其在中医中的应用
Pub Date : 2023-01-06 DOI: 10.1109/ISBP57705.2023.10061301
Ming Liu, Jianqiang Du, Zhiqing Li, Jigen Luo, Bin Nie, Mengting Zhang
The experimental data on traditional Chinese medicine efficacy has many irrelevant and redundant features, and different feature combinations have different effects. Therefore, we propose a hybrid multistage feature selection algorithm based on approximate Markov blanket and improved black widow algorithm. The first stage remove irrelevant features by the maximum information coefficient. The second stage delete redundant features from clustered searched by approximate Markov blanket by Lasso algorithm to avoid information loss. The third stage search the optimal feature subset by improved black widow algorithm that used the fast reproduction strategy, the child eating mother strategy and the population restriction strategy. The proposed approach is tested on the basic material data of traditional Chinese medicine and 9 UCI datasets, and compared with other feature selection algorithms. The experimental results show that the algorithm can obtain a small number of feature subsets with high accuracy, and has good time performance.
中药疗效实验数据存在许多不相关、冗余的特征,不同的特征组合效果不同。为此,我们提出了一种基于近似马尔可夫毯子和改进黑寡妇算法的混合多阶段特征选择算法。第一阶段通过最大信息系数去除不相关特征。第二阶段,利用Lasso算法从聚类搜索的近似马尔可夫毯中删除冗余特征,避免信息丢失;第三阶段采用改进的黑寡妇算法,结合快速繁殖策略、子吃母策略和种群限制策略,搜索最优特征子集。在中药基础材料数据和9个UCI数据集上对该方法进行了测试,并与其他特征选择算法进行了比较。实验结果表明,该算法能够以较高的准确率获得数量较少的特征子集,并具有良好的时效性。
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引用次数: 0
Glucose Prediction Based on the Recurrent Neural Network Model 基于递归神经网络模型的血糖预测
Pub Date : 2023-01-06 DOI: 10.1109/ISBP57705.2023.10061295
Yilin Zhang
An advanced convolutional neural network architecture for forecasting blood glucose is proposed in this paper. Four different measures are introduced in this essay, including Glucose, Meal, Insulin, and Time of the day, which are denoted as G, M, I, and T for short. Past 2-hour historical data of individuals are exploited to predict the future glucose level in 30 minutes with high accuracy. To verify the effectiveness of the blood glucose prediction model, three major methods have been displayed and compared. To be more specific, Recurrent Neural Network (RNN) was the better model for forecasting blood glucose, compared with Neural Network Predictive Glucose (NNPG) and Support Vector Regression (SVM). The metrics of evaluation are Root-Mean-Square deviation (RMSE) and Mean Absolute Relative Difference (MARD). The average of the best RMSE is 7.75, which is largely better than those of the other two models. This result shows the superior performance of RNN in accurate glucose prediction.
提出了一种用于血糖预测的卷积神经网络结构。本文介绍了四种不同的测量方法,包括葡萄糖,膳食,胰岛素和一天中的时间,简称为G, M, I和T。利用个体过去2小时的历史数据预测未来30分钟内的血糖水平,准确度高。为了验证血糖预测模型的有效性,展示并比较了三种主要方法。更具体地说,与神经网络预测血糖(NNPG)和支持向量回归(SVM)相比,递归神经网络(RNN)是更好的血糖预测模型。评价指标为均方根偏差(RMSE)和平均绝对相对差(MARD)。最佳RMSE的平均值为7.75,大大优于其他两个模型。这一结果显示了RNN在准确预测血糖方面的优越性能。
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引用次数: 0
期刊
2023 International Conference on Intelligent Supercomputing and BioPharma (ISBP)
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