{"title":"The effect of Xin-Nao-Xue-Mai-Ning on SD rats with hypothyroidism and IRE1-XBP1 signaling","authors":"Yongli Ren, J. Mou, YueJie Chu, Mingyong Ren, HanBo Cui, Xiaojuan Xu","doi":"10.53388/mmr2021017","DOIUrl":"https://doi.org/10.53388/mmr2021017","url":null,"abstract":"","PeriodicalId":313849,"journal":{"name":"Microenvironment and Microecology Research","volume":"2012 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114748056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiaomei Xu, Zuoyi Yang, Yaozhou Tian, Zhentao An, Yong-Shuang Wang, Hui Li
{"title":"Study on the effect of Xi-Feng-Hua-Shi granules on intestinal flora in patients with diarrhea-predominant irritable bowel syndrome based on 16S rDNA sequencing","authors":"Xiaomei Xu, Zuoyi Yang, Yaozhou Tian, Zhentao An, Yong-Shuang Wang, Hui Li","doi":"10.53388/mmr2022020","DOIUrl":"https://doi.org/10.53388/mmr2022020","url":null,"abstract":"","PeriodicalId":313849,"journal":{"name":"Microenvironment and Microecology Research","volume":"175 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126944936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: This study aimed to evaluate the effectiveness of midnight-noon ebb-flow (MNEF) theory guided moxibustion therapy for ankylosing spondylitis (AS) in terms of physical function, disease activity, health-related quality of life, inflammatory cytokines, and immune function biomarkers. Methods: 135 AS patients in Changzhou No. 2 hospital affiliated to Nanjing Medical University were randomly allocated to the control group, Moxibustion I group or the Moxibustion II group. AS patients in the control group received conventional intervention alone, while AS patients in the Moxibustion I group and Moxibustion II group received 4-week conventional moxibustion and MNEF theory-guided moxibustion therapy, respectively. Physical function, disease activity, health-related quality of life, inflammatory cytokines, and immune function biomarkers were assessed at baseline and at the endpoint week. Results: After moxibustion intervention, only performance of physical function measured by Bath Ankylosing Spondylitis Functional Index (BASFI) (F = 17.1, P < 0.01), and disease activity by the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) (F = 17, P < 0.01) were statistically significant differences between the three groups, and the Bath Ankylosing Spondylitis Metrology Index (BASMI) score were no group differences (F = 3.15, P = 0.07). The effect of MNEF-theory based moxibustion was shown to be better than conventional moxibustion therapy in the level of erythrocyte sedimentation rate (ESR) (2.67, 95% CI, 0.15 to 5.18; P = 0.04) and the radio of CD4 + CD25 + CD127 low (-2.83, 95% CI, -4.68 to -0.98; P < 0.01). However, with the use of the Tukey multiple comparisons test, compared with the conventional moxibustion therapy alone, MNEF-theory based moxibustion therapy had no statistically significant improvement in the serum levels of interleukin-6 (IL-6), interleukin-17 (IL-17), tumor necrosis factor α (TNF-α) ( P > 0.05). Conclusion: Overall, MNEF-theory guided moxibustion therapy significantly improved physical activity and health-related quality of life, reduced disease activity, and decreased systemic inflammation for AS patients.
{"title":"Moxibustion therapy guided by midnight-noon ebb-flow theory on Chinese patients with ankylosing spondylitis: a quasi-experimental study","authors":"Min Yan, Lijiangshan Hua, Xiao Zhou, Xiao Xu","doi":"10.53388/mmr2022011","DOIUrl":"https://doi.org/10.53388/mmr2022011","url":null,"abstract":"Objective: This study aimed to evaluate the effectiveness of midnight-noon ebb-flow (MNEF) theory guided moxibustion therapy for ankylosing spondylitis (AS) in terms of physical function, disease activity, health-related quality of life, inflammatory cytokines, and immune function biomarkers. Methods: 135 AS patients in Changzhou No. 2 hospital affiliated to Nanjing Medical University were randomly allocated to the control group, Moxibustion I group or the Moxibustion II group. AS patients in the control group received conventional intervention alone, while AS patients in the Moxibustion I group and Moxibustion II group received 4-week conventional moxibustion and MNEF theory-guided moxibustion therapy, respectively. Physical function, disease activity, health-related quality of life, inflammatory cytokines, and immune function biomarkers were assessed at baseline and at the endpoint week. Results: After moxibustion intervention, only performance of physical function measured by Bath Ankylosing Spondylitis Functional Index (BASFI) (F = 17.1, P < 0.01), and disease activity by the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) (F = 17, P < 0.01) were statistically significant differences between the three groups, and the Bath Ankylosing Spondylitis Metrology Index (BASMI) score were no group differences (F = 3.15, P = 0.07). The effect of MNEF-theory based moxibustion was shown to be better than conventional moxibustion therapy in the level of erythrocyte sedimentation rate (ESR) (2.67, 95% CI, 0.15 to 5.18; P = 0.04) and the radio of CD4 + CD25 + CD127 low (-2.83, 95% CI, -4.68 to -0.98; P < 0.01). However, with the use of the Tukey multiple comparisons test, compared with the conventional moxibustion therapy alone, MNEF-theory based moxibustion therapy had no statistically significant improvement in the serum levels of interleukin-6 (IL-6), interleukin-17 (IL-17), tumor necrosis factor α (TNF-α) ( P > 0.05). Conclusion: Overall, MNEF-theory guided moxibustion therapy significantly improved physical activity and health-related quality of life, reduced disease activity, and decreased systemic inflammation for AS patients.","PeriodicalId":313849,"journal":{"name":"Microenvironment and Microecology Research","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126319092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.53388/tmer202010101002
Yongyan Wang, Jingjing Liu, ZhenTao Di, S. Lu, Yangcang Xu
{"title":"Regulation of cytokine storm by marine traditional Chinese medicine","authors":"Yongyan Wang, Jingjing Liu, ZhenTao Di, S. Lu, Yangcang Xu","doi":"10.53388/tmer202010101002","DOIUrl":"https://doi.org/10.53388/tmer202010101002","url":null,"abstract":"","PeriodicalId":313849,"journal":{"name":"Microenvironment and Microecology Research","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116763712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
the most common chronic joint degenerative disease in the population, involving progressive focal cartilage degeneration, bone hypertrophy (osteophyte formation and subchondral osteosclerosis), synovial joint inflammation, synovial sac thickening
{"title":"Progress in the effect of inflammatory microenvironment on osteoarthritis","authors":"Andong Zhao, Ping Xin, Yixuan Fan, Xiao-Hui Yang, Jia-Xin Yuan, Xin-Ju Li","doi":"10.53388/mmr2023009","DOIUrl":"https://doi.org/10.53388/mmr2023009","url":null,"abstract":"the most common chronic joint degenerative disease in the population, involving progressive focal cartilage degeneration, bone hypertrophy (osteophyte formation and subchondral osteosclerosis), synovial joint inflammation, synovial sac thickening","PeriodicalId":313849,"journal":{"name":"Microenvironment and Microecology Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123563194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Research progress of traditional medicine to improve colorectal tumor from the perspective of intestinal flora","authors":"Weichen Si","doi":"10.53388/mmr2022016","DOIUrl":"https://doi.org/10.53388/mmr2022016","url":null,"abstract":"","PeriodicalId":313849,"journal":{"name":"Microenvironment and Microecology Research","volume":"347 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125902506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.53388/tmer202010201002
Shudi Yang, Jingcheng Song, Yue Gao, B. Cui
{"title":"Application and challenges of RNA interference in reversing multidrug resistance of tumor cells","authors":"Shudi Yang, Jingcheng Song, Yue Gao, B. Cui","doi":"10.53388/tmer202010201002","DOIUrl":"https://doi.org/10.53388/tmer202010201002","url":null,"abstract":"","PeriodicalId":313849,"journal":{"name":"Microenvironment and Microecology Research","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114604633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Teng Li, Xiao-hui Yu, Ming Xu, Yu-Hui Wang, Wenkai Zhao, Mei-Rou Liang, Yi Fan
{"title":"Research progress of traditional Chinese medicine compound in the treatment of gout based on intestinal flora","authors":"Teng Li, Xiao-hui Yu, Ming Xu, Yu-Hui Wang, Wenkai Zhao, Mei-Rou Liang, Yi Fan","doi":"10.53388/mmr2023003","DOIUrl":"https://doi.org/10.53388/mmr2023003","url":null,"abstract":"","PeriodicalId":313849,"journal":{"name":"Microenvironment and Microecology Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121891704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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