{"title":"New horizon: microenvironment regulation in neurodegenerative diseases","authors":"Y. Jiao, Yang Yang","doi":"10.53388/mmr2023010","DOIUrl":"https://doi.org/10.53388/mmr2023010","url":null,"abstract":"","PeriodicalId":313849,"journal":{"name":"Microenvironment and Microecology Research","volume":"189 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132755955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Dou, Zixuan Wang, Shih-Hao Wang, Meng Dong, Fei Wang, Yu Gou, Sheng-jun Sun, Yong-Qi Kang
Objective: To investigate the mechanism of action and efficacy of Shi-Pi-San (SPS) in the treatment of cirrhotic ascites based on intestinal flora and to provide new ideas for clinical research. Methods: We searched PubMed, CNKI, Wanfang and Wipu Chinese journal databases to collect randomized controlled trials of SPS in the treatment of cirrhotic ascites, extracted relevant data, and summarized them to analyze the relationship between intestinal flora and cirrhotic ascites. Results: The disorder of intestinal flora can lead to cirrhotic ascites, and the treatment of cirrhotic ascites with SPS has good efficacy, and SPS has positive effects in improving the status of intestinal flora, increasing the abundance of flora and inhibiting the growth of pathogenic bacteria. Conclusion: SPS has good long-term efficacy in the treatment of cirrhotic ascites, but the side effects and dosage criteria have not been extensively studied in clinical practice.
{"title":"Exploring the mechanism of action and efficacy of Shi-Pi-San in the treatment of ascites in cirrhosis based on intestinal microbiota","authors":"M. Dou, Zixuan Wang, Shih-Hao Wang, Meng Dong, Fei Wang, Yu Gou, Sheng-jun Sun, Yong-Qi Kang","doi":"10.53388/mmr2023006","DOIUrl":"https://doi.org/10.53388/mmr2023006","url":null,"abstract":"Objective: To investigate the mechanism of action and efficacy of Shi-Pi-San (SPS) in the treatment of cirrhotic ascites based on intestinal flora and to provide new ideas for clinical research. Methods: We searched PubMed, CNKI, Wanfang and Wipu Chinese journal databases to collect randomized controlled trials of SPS in the treatment of cirrhotic ascites, extracted relevant data, and summarized them to analyze the relationship between intestinal flora and cirrhotic ascites. Results: The disorder of intestinal flora can lead to cirrhotic ascites, and the treatment of cirrhotic ascites with SPS has good efficacy, and SPS has positive effects in improving the status of intestinal flora, increasing the abundance of flora and inhibiting the growth of pathogenic bacteria. Conclusion: SPS has good long-term efficacy in the treatment of cirrhotic ascites, but the side effects and dosage criteria have not been extensively studied in clinical practice.","PeriodicalId":313849,"journal":{"name":"Microenvironment and Microecology Research","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115329112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Research progress on the role of tumor microenvironment in tumor metastasis","authors":"Xiao-hua Liu","doi":"10.53388/tmer201900015","DOIUrl":"https://doi.org/10.53388/tmer201900015","url":null,"abstract":"","PeriodicalId":313849,"journal":{"name":"Microenvironment and Microecology Research","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128476703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tumor microenvironment and immune surveillance","authors":"Aamir N. Ahmad","doi":"10.53388/mmr2022006","DOIUrl":"https://doi.org/10.53388/mmr2022006","url":null,"abstract":"","PeriodicalId":313849,"journal":{"name":"Microenvironment and Microecology Research","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133799550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lester Raymundo Dominguez Huarcaya, María Fernanda Dominguez Ríos
The highest rates of morbidity and impairment related to gastrointestinal difficulties are associated with depression, which is associated with the highest rates of all mental disorders. It has been demonstrated that the composition of an individual's gut microbiome plays a significant part in determining that person's risk of developing depression. According to the hypothesis known as the gut-brain axis, there may be a connection between the intestinal microbial system and the brain. In recent years, it has been common practice to treat disorders by concentrating on the bacteria that are found in the digestive tract (for instance, by making use of probiotics) and incorporating the gut-brain axis mechanism. Our research revealed a remarkable association between the composition of the bacteria in the stomach and the incidence of depression. Alterations in the structure of the microbiota system in the gut could possibly have direct and special impacts on the rise in the prevalence of depression. This study investigated the mechanisms underlying the two-way communication in the gut-brain axis, including the current techniques of relieving symptoms and antidepressant medicines that are related to gut microbiota. An increase in the amount of research into the medical potential of probiotics has led to a rapid expansion of the field of probiotics over the past few decades. Numerous preclinical and clinical studies have established that the therapeutic effects of probiotics-mediated microbiota remodeling near the microbiota-gut-brain axis (MGBA) are present. These studies were conducted near one another. However, the potential effects of probiotics on numerous mental illnesses, which have been proved in vivo and in vitro research, have set the ground for the translation of preclinical models to humans, which is still in its infancy.
{"title":"Microbiota and depression an update","authors":"Lester Raymundo Dominguez Huarcaya, María Fernanda Dominguez Ríos","doi":"10.53388/mmr2023008","DOIUrl":"https://doi.org/10.53388/mmr2023008","url":null,"abstract":"The highest rates of morbidity and impairment related to gastrointestinal difficulties are associated with depression, which is associated with the highest rates of all mental disorders. It has been demonstrated that the composition of an individual's gut microbiome plays a significant part in determining that person's risk of developing depression. According to the hypothesis known as the gut-brain axis, there may be a connection between the intestinal microbial system and the brain. In recent years, it has been common practice to treat disorders by concentrating on the bacteria that are found in the digestive tract (for instance, by making use of probiotics) and incorporating the gut-brain axis mechanism. Our research revealed a remarkable association between the composition of the bacteria in the stomach and the incidence of depression. Alterations in the structure of the microbiota system in the gut could possibly have direct and special impacts on the rise in the prevalence of depression. This study investigated the mechanisms underlying the two-way communication in the gut-brain axis, including the current techniques of relieving symptoms and antidepressant medicines that are related to gut microbiota. An increase in the amount of research into the medical potential of probiotics has led to a rapid expansion of the field of probiotics over the past few decades. Numerous preclinical and clinical studies have established that the therapeutic effects of probiotics-mediated microbiota remodeling near the microbiota-gut-brain axis (MGBA) are present. These studies were conducted near one another. However, the potential effects of probiotics on numerous mental illnesses, which have been proved in vivo and in vitro research, have set the ground for the translation of preclinical models to humans, which is still in its infancy.","PeriodicalId":313849,"journal":{"name":"Microenvironment and Microecology Research","volume":"430 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116001352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Practical implementation of nutritional serves, gut microbiome, combination therapy, and nutraceuticals supplements","authors":"Reyed M","doi":"10.53388/mmr2022008","DOIUrl":"https://doi.org/10.53388/mmr2022008","url":null,"abstract":"","PeriodicalId":313849,"journal":{"name":"Microenvironment and Microecology Research","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128070738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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