首页 > 最新文献

Family Practice and Palliative Care最新文献

英文 中文
Pediatrik Pes Planus (düztabanlık) 儿科Pes Planus
Pub Date : 2022-10-19 DOI: 10.22391/fppc.1065797
Nazan Kaymaz, Burak Kaymaz
Flatfoot (pes planus) is described as a reduction or absence of the medial longitudinal arch (MLA) of the foot, with or without additional deformities of the foot and ankle. It is a very common orthopedic manifestation in infants and children and usually resolves by adolescence. Flat foot is usually flexible and painless with no functional compromise so that described as physiologic. In some rare cases flatfoot can become painful or rigid and may be a sign of pathology such as vertical talus or tarsal coalition. Although it is very common, there is no standard definition and no universally accepted classification system for pediatric flatfoot. Furthermore there are no large, prospective studies comparing the natural history of flatfoot in response to various treatments during the developmental period. Current literature suggests that it is safe and appropriate to simply observe an asymptomatic child with flatfoot. Painful flexible flatfoot may benefit from orthopedic intervention such as physical therapy, orthosis or sometimes a surgical procedure.Keywords: Pes planus, flatfoot, infant, child, foot arch, surgery
扁平足(pes planus)被描述为足部内侧纵弓(MLA)减少或缺失,伴有或不伴有足部和脚踝的额外畸形。它是婴儿和儿童的一种非常常见的骨科表现,通常在青春期解决。平足通常是灵活和无痛的,没有功能损害,因此被描述为生理性的。在一些罕见的情况下,扁平足会变得疼痛或僵硬,可能是病理学的迹象,如垂直距骨或跗骨联盟。尽管它很常见,但对于儿童扁平足没有标准的定义,也没有普遍接受的分类系统。此外,还没有大型前瞻性研究比较扁平足的自然史对发育期各种治疗的反应。目前的文献表明,简单地观察无症状的扁平足儿童是安全和合适的。疼痛的柔性扁平足可能受益于骨科干预,如物理治疗、矫形器或有时的外科手术。关键词:平足、扁平足、婴儿、儿童、足弓、外科
{"title":"Pediatrik Pes Planus (düztabanlık)","authors":"Nazan Kaymaz, Burak Kaymaz","doi":"10.22391/fppc.1065797","DOIUrl":"https://doi.org/10.22391/fppc.1065797","url":null,"abstract":"Flatfoot (pes planus) is described as a reduction or absence of the medial longitudinal arch (MLA) of the foot, with or without additional deformities of the foot and ankle. It is a very common orthopedic manifestation in infants and children and usually resolves by adolescence. Flat foot is usually flexible and painless with no functional compromise so that described as physiologic. In some rare cases flatfoot can become painful or rigid and may be a sign of pathology such as vertical talus or tarsal coalition. Although it is very common, there is no standard definition and no universally accepted classification system for pediatric flatfoot. Furthermore there are no large, prospective studies comparing the natural history of flatfoot in response to various treatments during the developmental period. Current literature suggests that it is safe and appropriate to simply observe an asymptomatic child with flatfoot. Painful flexible flatfoot may benefit from orthopedic intervention such as physical therapy, orthosis or sometimes a surgical procedure.Keywords: Pes planus, flatfoot, infant, child, foot arch, surgery","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48834497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
İlaç alerjisi olan hastalarda otoantikor sıklığı 药物过敏患者有一个自动频率
Pub Date : 2022-10-14 DOI: 10.22391/fppc.1134893
Zeynep Altın, Papatya BAYRAK DEĞİRMENCİ
Giriş: Bu çalışma, ilaç alerjisi olan hastalarda otoantikor sıklığını incelemeyi amaçlamaktadır. İlaç alerjisi üzerine gözlemsel araştırmalar, otoimmünite patofizyolojisi hakkında yeni hipotezlerin oluşturulmasına katkıda bulunabilir.Yöntem: Eğitim ve Araştırma Hastanesi veri tabanına 31 Aralık 2018 sonuna kadar kayıt olan ve ilaç alerjisi tanısı konan hastaların verileri geriye dönük olarak değerlendirildi. Genel olarak, ICD 10'a göre “ilaçlara alerji durumu” tanısı konan ve en az bir otoantikor sonucu olan 617 adet yetişkin hasta çalışmaya dahil edildi.Bulgular: Araştırmada en az bir otoantikora sahip olma sıklığı % 0 ile % 92,1 arasında değişti. En sık saptanan otoantikor romatoid faktör (RF) idi (n = 241; % 92,1). İkinci en sık rastlanan oto antikorun anti-doku transglütaminaz IgA (Anti-tTG-IgA) (n = 22; % 68,2) olduğu görüldü. Anti-tiroglobulin (Anti-TG), anti-tiroid peroksidaz (anti-TPO) ve anti-çift sarmallı DNA (Anti-dsDNA) sıklıkları sırasıyla % 65,2 (n = 155), % 59,7 (n = 159) ve % 43,6 (n = 55) olarak saptandı.Sonuç: Birçok ilaç, otoimmün hastalıkları için ilerleme olmaksızın otoantikor gelişimini tetikleyebilir. İlaçlara alerjisi olan hastalarda otoantikorlardan şüphelenilmesi gereklidir. İlaç alerjisi üzerine yapılan gözlemsel araştırmalar, otoimmünitenin patofizyolojisi hakkında yeni hipotezlerin oluşturulmasına katkı sağlayacaktır. Bu alanda yapılacak çok sayıda çalışma, riskli ilaçların yaygın kullanımını daha objektif bir şekilde tartışmamızı sağlayabilir. Çalışmamızın ilaç reaksiyonu ile otoimmün hastalıklar arasındaki ilişkiye ışık tutacağını düşünüyoruz.Anahtar kelimeler: Otoantikorlar, otoimmünite, ilaç alerjisi, ilaç aşırı duyarlılığı
条目:在药物过敏患者中,本研究旨在调查自动频率。对药物过敏的观察研究可以帮助建立关于自主性病理生理学的新假设。方法:教育和研究医院的数据库记录到2018年12月31日,诊断为药物过敏的患者的数据被评估为反向。一般来说,根据ICD 10,617名自身免疫后果较少的成年患者被确定为“药物过敏”。事件:研究中的自主抗体拥有率在0%到92.1%之间变化。最常见的分离的自身抗肿瘤因子(RF)(n=241;%92.1)。第二常见的汽车解毒剂反谷氨酰胺IgA(Anti-tTG IgA)(n=22;%68.2)。抗替罗布林(抗TG)、抗替罗匹克司达(抗TPO)ve抗-SarmalıDNA(抗dsDNA)sıklıklarısırasıyla%65.2(n=155)、%59.7(n=159)ve%43.6(n=55)olarak saptandı。Sonuç:Birçok ilaç,otoimmün hastalıklrıiçin ilerleme olmaksızın otoantikor gelişimini tetikleyebilir。过敏患者应怀疑有自身抗体。对药物过敏的观察研究将有助于建立关于自主病理学的新假设。在这方面,我们可以更客观地讨论危险药物的常见用途。我们认为我们的工作将在药物反应和自主性疾病之间保持平衡。关键词:自主性,自主性,药物过敏,药物超敏反应。
{"title":"İlaç alerjisi olan hastalarda otoantikor sıklığı","authors":"Zeynep Altın, Papatya BAYRAK DEĞİRMENCİ","doi":"10.22391/fppc.1134893","DOIUrl":"https://doi.org/10.22391/fppc.1134893","url":null,"abstract":"Giriş: Bu çalışma, ilaç alerjisi olan hastalarda otoantikor sıklığını incelemeyi amaçlamaktadır. İlaç alerjisi üzerine gözlemsel araştırmalar, otoimmünite patofizyolojisi hakkında yeni hipotezlerin oluşturulmasına katkıda bulunabilir.Yöntem: Eğitim ve Araştırma Hastanesi veri tabanına 31 Aralık 2018 sonuna kadar kayıt olan ve ilaç alerjisi tanısı konan hastaların verileri geriye dönük olarak değerlendirildi. Genel olarak, ICD 10'a göre “ilaçlara alerji durumu” tanısı konan ve en az bir otoantikor sonucu olan 617 adet yetişkin hasta çalışmaya dahil edildi.Bulgular: Araştırmada en az bir otoantikora sahip olma sıklığı % 0 ile % 92,1 arasında değişti. En sık saptanan otoantikor romatoid faktör (RF) idi (n = 241; % 92,1). İkinci en sık rastlanan oto antikorun anti-doku transglütaminaz IgA (Anti-tTG-IgA) (n = 22; % 68,2) olduğu görüldü. Anti-tiroglobulin (Anti-TG), anti-tiroid peroksidaz (anti-TPO) ve anti-çift sarmallı DNA (Anti-dsDNA) sıklıkları sırasıyla % 65,2 (n = 155), % 59,7 (n = 159) ve % 43,6 (n = 55) olarak saptandı.Sonuç: Birçok ilaç, otoimmün hastalıkları için ilerleme olmaksızın otoantikor gelişimini tetikleyebilir. İlaçlara alerjisi olan hastalarda otoantikorlardan şüphelenilmesi gereklidir. İlaç alerjisi üzerine yapılan gözlemsel araştırmalar, otoimmünitenin patofizyolojisi hakkında yeni hipotezlerin oluşturulmasına katkı sağlayacaktır. Bu alanda yapılacak çok sayıda çalışma, riskli ilaçların yaygın kullanımını daha objektif bir şekilde tartışmamızı sağlayabilir. Çalışmamızın ilaç reaksiyonu ile otoimmün hastalıklar arasındaki ilişkiye ışık tutacağını düşünüyoruz.Anahtar kelimeler: Otoantikorlar, otoimmünite, ilaç alerjisi, ilaç aşırı duyarlılığı","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45408111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bel fıtığına bağlı bel ağrısının uyku, yaşam kalitesi ve depresyon belirtileri üzerine olan etkileri
Pub Date : 2022-10-14 DOI: 10.22391/fppc.960875
Ümit Ali Malçok
Introduction: This study aims to evaluate the relationship between herniated disc-related low back pain and depression, sleep, and quality of life.Methods: A control group consisting of 28 patients with herniated disc-related pain and 28 healthy volunteers were included in the study. Beck Depression Inventory (BDI) and Quality of Life Index (SF-36) are applied to all groups. Pain severity was evaluated with the Visual Analogue Scale (VAS). Sleep parameters were analyzed with an actigraphy device.Results: Depression and quality of life scores differed between the two groups, and they were observed as significantly higher in the group with herniated disc. Moreover, there was a positive correlation between pain severity and depression. On the other hand, there was a negative correlation between pain intensity and sleep efficiency. Subjects with low back pain had worse sleep quality and lower sleep efficiency (mean 71.7%) than the control group. The logistic regression analysis found a significant relationship between depression and VAS pain variables (p=0.030; 95% CI: 0.021-0.823).Conclusions: Our study's results reveal a relationship between pain and depression in herniated disc patients. Moreover, it was concluded that the deteriorated sleep quality due to low back pain also increased the severity of depression. This relationship related to the unpleasant consequences of chronic pain should be taken into account when planning the medical treatment and follow-up of patients with herniated disc, and also when explaining their expectations from surgical treatment.Keywords: Herniated disc, pain, sleep, depression, actigraphy.
前言:本研究旨在评估椎间盘突出相关腰痛与抑郁、睡眠和生活质量的关系。方法:将28例腰椎间盘突出相关疼痛患者和28例健康志愿者作为对照组。各组采用贝克抑郁量表(BDI)和生活质量指数(SF-36)。用视觉模拟量表(VAS)评估疼痛严重程度。用活动记录仪分析睡眠参数。结果:两组患者抑郁和生活质量评分存在差异,椎间盘突出组抑郁和生活质量评分明显高于对照组。此外,疼痛严重程度与抑郁之间存在正相关。另一方面,疼痛强度与睡眠效率呈负相关。与对照组相比,腰痛患者的睡眠质量和睡眠效率较差(平均71.7%)。logistic回归分析发现抑郁与VAS疼痛变量之间存在显著相关(p=0.030;95% ci: 0.021-0.823)。结论:我们的研究结果揭示了椎间盘突出患者疼痛和抑郁之间的关系。此外,由于腰痛导致的睡眠质量恶化也增加了抑郁症的严重程度。在规划椎间盘突出患者的医疗和随访时,以及在解释他们对手术治疗的期望时,应考虑到这种与慢性疼痛不良后果相关的关系。关键词:椎间盘突出,疼痛,睡眠,抑郁,活动图。
{"title":"Bel fıtığına bağlı bel ağrısının uyku, yaşam kalitesi ve depresyon belirtileri üzerine olan etkileri","authors":"Ümit Ali Malçok","doi":"10.22391/fppc.960875","DOIUrl":"https://doi.org/10.22391/fppc.960875","url":null,"abstract":"Introduction: This study aims to evaluate the relationship between herniated disc-related low back pain and depression, sleep, and quality of life.Methods: A control group consisting of 28 patients with herniated disc-related pain and 28 healthy volunteers were included in the study. Beck Depression Inventory (BDI) and Quality of Life Index (SF-36) are applied to all groups. Pain severity was evaluated with the Visual Analogue Scale (VAS). Sleep parameters were analyzed with an actigraphy device.Results: Depression and quality of life scores differed between the two groups, and they were observed as significantly higher in the group with herniated disc. Moreover, there was a positive correlation between pain severity and depression. On the other hand, there was a negative correlation between pain intensity and sleep efficiency. Subjects with low back pain had worse sleep quality and lower sleep efficiency (mean 71.7%) than the control group. The logistic regression analysis found a significant relationship between depression and VAS pain variables (p=0.030; 95% CI: 0.021-0.823).Conclusions: Our study's results reveal a relationship between pain and depression in herniated disc patients. Moreover, it was concluded that the deteriorated sleep quality due to low back pain also increased the severity of depression. This relationship related to the unpleasant consequences of chronic pain should be taken into account when planning the medical treatment and follow-up of patients with herniated disc, and also when explaining their expectations from surgical treatment.Keywords: Herniated disc, pain, sleep, depression, actigraphy.","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43884374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Çocukluk çağında bruselloz: 37 olgunun retrospektif değerlendirilmesi ve literatürün gözden geçirilmesi 儿童布鲁塞尔菌病:37岁年龄和文献的回顾性评价
Pub Date : 2022-07-31 DOI: 10.22391/fppc.1035377
Taylan Çelik, Emre Kaan
Introduction: The aim of this study is to evaluate the demographic, clinical and laboratory characteristics and treatment results of pediatric patients followed up with the diagnosis of brucellosis in our clinic.Methods: Patients who were followed up with the diagnosis of brucellosis in Kayseri Training and Research Hospital, Pediatric Infectious Diseases Clinic between October 2016 and December 2018 were retrospectively analyzed.Results: A total of 37 patients, 26 (70.3%) male, were included in the study. The mean age of the patients whose ages ranged from 1 to 17 years was 9.3±4.3 years. Unpasteurized milk and/or dairy products were consumed in 86.5% of the patients and 48.6% had a family history of brucellosis. Joint pain (75.7%) was the most common presenting complaint. In the laboratory evaluation, 8.1% of the patients had leukopenia, 2.7% had thrombocytopenia and 21.4% had ALT elevation. Doxycycline plus rifampicin (43.2%) was the most commonly preferred treatment regimen. Addition of aminoglycoside to initial therapy in hospitalized patients was statistically higher than in outpatients (81.2% vs. 23.8%) (p=0.001). During the follow-up, relapse developed in a total of 4 (10.8%) patients, 3 of whom were outpatients. There was no statistical relationship between the initial treatment regimen and relapse (p=0.418).Conclusion: In conclusion, brucellosis should be kept in mind in terms of differential diagnosis in patients who present with joint pain in our country and who have cytopenia and/or isolated aminotransferase elevation in their investigations.Keywords: Child, Brucellosis, Relapse
引言:本研究的目的是评估我们诊所诊断为布鲁氏菌病的儿童患者的人口统计学、临床和实验室特征以及治疗结果。方法:对2016年10月至2018年12月在凯塞里培训研究医院儿科传染病门诊随访诊断为布鲁氏菌病的患者进行回顾性分析。结果:共有37例患者,其中26例(70.3%)为男性。年龄1~17岁的患者平均年龄为9.3±4.3岁。86.5%的患者食用未经高温消毒的牛奶和/或乳制品,48.6%的患者有布鲁氏菌病家族史。关节疼痛(75.7%)是最常见的主诉。在实验室评估中,8.1%的患者白细胞减少,2.7%的患者血小板减少,21.4%的患者ALT升高。多西环素加利福平(43.2%)是最常用的治疗方案。住院患者在初始治疗中添加氨基糖苷的比例在统计学上高于门诊患者(81.2%对23.8%)(p=0.001)。在随访期间,共有4名(10.8%)患者复发,其中3名为门诊患者。初始治疗方案与复发之间没有统计学关系(p=0.418)。关键词:儿童,布鲁氏菌病,复发
{"title":"Çocukluk çağında bruselloz: 37 olgunun retrospektif değerlendirilmesi ve literatürün gözden geçirilmesi","authors":"Taylan Çelik, Emre Kaan","doi":"10.22391/fppc.1035377","DOIUrl":"https://doi.org/10.22391/fppc.1035377","url":null,"abstract":"Introduction: The aim of this study is to evaluate the demographic, clinical and laboratory characteristics and treatment results of pediatric patients followed up with the diagnosis of brucellosis in our clinic.Methods: Patients who were followed up with the diagnosis of brucellosis in Kayseri Training and Research Hospital, Pediatric Infectious Diseases Clinic between October 2016 and December 2018 were retrospectively analyzed.Results: A total of 37 patients, 26 (70.3%) male, were included in the study. The mean age of the patients whose ages ranged from 1 to 17 years was 9.3±4.3 years. Unpasteurized milk and/or dairy products were consumed in 86.5% of the patients and 48.6% had a family history of brucellosis. Joint pain (75.7%) was the most common presenting complaint. In the laboratory evaluation, 8.1% of the patients had leukopenia, 2.7% had thrombocytopenia and 21.4% had ALT elevation. Doxycycline plus rifampicin (43.2%) was the most commonly preferred treatment regimen. Addition of aminoglycoside to initial therapy in hospitalized patients was statistically higher than in outpatients (81.2% vs. 23.8%) (p=0.001). During the follow-up, relapse developed in a total of 4 (10.8%) patients, 3 of whom were outpatients. There was no statistical relationship between the initial treatment regimen and relapse (p=0.418).Conclusion: In conclusion, brucellosis should be kept in mind in terms of differential diagnosis in patients who present with joint pain in our country and who have cytopenia and/or isolated aminotransferase elevation in their investigations.Keywords: Child, Brucellosis, Relapse","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46795221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hastane öncesi acil sağlık çalışanlarının meslek hastalığı risk faktörleri ile ilgili bilgi düzeyleri ve etkileyen faktörler 住院前,信息水平和影响因素受医疗专业人员风险因素影响
Pub Date : 2022-07-31 DOI: 10.22391/fppc.1114859
Ferit Kaya, A. Oğuzöncül, Ramazan Gürgöze, Medine Kaya
Giriş: Meslek hastalıkları günümüzde giderek önemini arttırmaktadır. Bu çalışmanın amacı hastane öncesi sağlık hizmeti çalışanlarının, meslek hastalıkları ile ilgili karşılaşabilecekleri risk faktörlerine yönelik bilgi düzeylerini ve etkileyen faktörleri belirlemektir.Yöntem: Bu araştırma kesitsel tipte bir çalışmadır. Çalışmanın evrenini Elazığ ili hastane öncesi acil sağlık hizmetlerinde çalışan 504 personel oluşturmuştur. Örneklem grubu seçilmemiş olup evrenin tamamına ulaşılması planlanmıştır. Anket 25 sorudan oluşmaktadır. Gönüllülük esasına dayalı olarak yüz yüze görüşme yöntemi ile anket uygulanmıştır. Anketlere katılım oranı %84,6 olarak gerçekleşmiştir. Elde edilen veriler istatistik paket programa kaydedilmiştir. İstatistiksel analiz için X² ve Fisher’s Exact test kullanılmıştır.Bulgular: Katılımcıların yaş ortalaması 30,61±9,83’ idi. Çalışanların %59,6’sı kadın, %40,9’u paramedik ve %55,4’ü ilçe istasyonların da çalışmaktaydı. Mesleği isteyerek seçenlerin oranı %90,2’di. Çalışanların %93,0’ı mesleklerinin kas iskelet sistemi hastalıkları için risk oluşturduğunu düşünüyordu. Çalışanların %69,6’sı için şiddete maruz kalma riski stres oluşturan ana faktördü.Sonuç: Katılımcıların çoğunluğu mesleği isteyerek seçmiştir. Mesleki risk faktörü olarak en sık ergonomik faktörler görülmektedir. Nöbet süresinin uzun olması doktorlar arasında, nöbet arkadaşının uyumsuz olmasını ise acil tıp teknisyenleri (ATT) arasında yüksek oranda stres kaynağıdır. Sağlık çalışanlarına yönelik meslek hastalıkları konusunda eğitimlerin sıklaştırılması, HBV bulaşı gibi sık bilinen enfeksiyonlar dışında diğer biyolojik risk faktörlerine ve kimyasal risk faktörlerine karşıda duyarlılığın arttırılması yanında şiddete karşı önlemlerin arttırılması önerilmektedir.Anahtar kelimeler: Meslek hastalıkları, sağlık çalışanları, risk faktörleri, acil servis, ergonomi
入门:如今,就业疾病正在增加。这项研究的目的是确定可以在住院前向卫生工作者、专业疾病提供的信息水平和因素。方法:本研究为部分研究。Çalışmanın evrenini Elazığili hastaneöncesi acil sağlık hizmetrindeçalı。尚未选择模型组,并且已到达整个宇宙。这篇文章大约有25个问题。采用面对面访谈的方法,在随机性的基础上进行问卷调查。民意调查的参与率为84.6%。收集的数据存储在统计包程序中。为了进行统计分析,使用了X²和Fisher精确检验。例如:参与者的平均年龄为30.61±9.83'。59.6%的工人是妇女,40.9%是妇女,55.4%在该县。90.2%的人选择找工作。93.0%的工人认为肌肉骨骼系统有患病风险。Çalışanların%69,6的ıiçinşiddete maruz kalma riski stres oluşturan ana faktördü。Sonuç:Katılımcılarınçoğunluğu mesleği isteyerek seçmiştir。最常见的人体工程学因素被视为职业风险因素。医生之间的长期死亡率是急诊医学工程师(ATT)之间的高压力率。关键是要增加对其他生物风险因素和化学风险因素的暴力,除了频繁的HBV相关感染,培训被减少为与工作相关的疾病。卫生工作者、风险因素、急救服务、工效学
{"title":"Hastane öncesi acil sağlık çalışanlarının meslek hastalığı risk faktörleri ile ilgili bilgi düzeyleri ve etkileyen faktörler","authors":"Ferit Kaya, A. Oğuzöncül, Ramazan Gürgöze, Medine Kaya","doi":"10.22391/fppc.1114859","DOIUrl":"https://doi.org/10.22391/fppc.1114859","url":null,"abstract":"Giriş: Meslek hastalıkları günümüzde giderek önemini arttırmaktadır. Bu çalışmanın amacı hastane öncesi sağlık hizmeti çalışanlarının, meslek hastalıkları ile ilgili karşılaşabilecekleri risk faktörlerine yönelik bilgi düzeylerini ve etkileyen faktörleri belirlemektir.Yöntem: Bu araştırma kesitsel tipte bir çalışmadır. Çalışmanın evrenini Elazığ ili hastane öncesi acil sağlık hizmetlerinde çalışan 504 personel oluşturmuştur. Örneklem grubu seçilmemiş olup evrenin tamamına ulaşılması planlanmıştır. Anket 25 sorudan oluşmaktadır. Gönüllülük esasına dayalı olarak yüz yüze görüşme yöntemi ile anket uygulanmıştır. Anketlere katılım oranı %84,6 olarak gerçekleşmiştir. Elde edilen veriler istatistik paket programa kaydedilmiştir. İstatistiksel analiz için X² ve Fisher’s Exact test kullanılmıştır.Bulgular: Katılımcıların yaş ortalaması 30,61±9,83’ idi. Çalışanların %59,6’sı kadın, %40,9’u paramedik ve %55,4’ü ilçe istasyonların da çalışmaktaydı. Mesleği isteyerek seçenlerin oranı %90,2’di. Çalışanların %93,0’ı mesleklerinin kas iskelet sistemi hastalıkları için risk oluşturduğunu düşünüyordu. Çalışanların %69,6’sı için şiddete maruz kalma riski stres oluşturan ana faktördü.Sonuç: Katılımcıların çoğunluğu mesleği isteyerek seçmiştir. Mesleki risk faktörü olarak en sık ergonomik faktörler görülmektedir. Nöbet süresinin uzun olması doktorlar arasında, nöbet arkadaşının uyumsuz olmasını ise acil tıp teknisyenleri (ATT) arasında yüksek oranda stres kaynağıdır. Sağlık çalışanlarına yönelik meslek hastalıkları konusunda eğitimlerin sıklaştırılması, HBV bulaşı gibi sık bilinen enfeksiyonlar dışında diğer biyolojik risk faktörlerine ve kimyasal risk faktörlerine karşıda duyarlılığın arttırılması yanında şiddete karşı önlemlerin arttırılması önerilmektedir.Anahtar kelimeler: Meslek hastalıkları, sağlık çalışanları, risk faktörleri, acil servis, ergonomi","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47938545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Minör göğüs travmasında radyografinin kaburga kırıklarını tanımada yeterliliği: Sonografi ve radyografinin etkinlik kıyaslaması 足以检测腹部骨折的x线平片在轻微胸部创伤中的应用:一项概要和x线平片效率比较
Pub Date : 2022-07-31 DOI: 10.22391/fppc.1033620
Emre Yurdakul, Servet Kahveci̇
Introduction: The most common injury resulting from blunt chest trauma is a rib fracture (25%) which is usually visible on radiographs. However, radiographs sometimes cannot show fractures, especially those in cartilage, unless they're densely calcified. The present study aimed to investigate the role of ultrasonography (US) in detecting rib fractures with minor blunt chest trauma and comparing its success with posteroanterior (PA) chest radiography.Methods: Patients with minor blunt chest trauma who had previously undergone US and radiography to assess suspected rib fractures, between June 2017– March 2019, were included. Radiography was obtained in the PA projection. US was performed by a radiologist who identified fractures by the disruption of the anterior margin of the rib on the US. The incidence and location of the fractures detected by US and radiography were then compared.Results: Totally 126 patients were included in the study. Ninety-eight patients (78%) were admitted to the hospital for the first time, and 28 patients (22%) for the second time (they previously admitted to the other hospitals and were evaluated as ‘normal’ by radiography). A total of 108 fractures ( in 79 patients (63%) ) were detected based on radiography and US examination, while 47 patients (37%) had no diagnostic evidence of fracture. All fractures were correctly detected by ultrasonography (100%), whereas radiography revealed 16 fractures (14.81%). A statistically significant difference in diagnostic capability was found between patients diagnosed by radiography and US (p=0.001).Conclusion: Ultrasonographic imaging is significantly superior to radiography in terms of accuracy in diagnosing rib fractures. Ultrasound was found to be significantly superior to radiography regardless of trauma site, localization, and location. Even though some rib areas are inaccessible on ultrasonographic evaluation, rapid evaluation of the most affected areas is most effective with ultrasonography when it comes to minor energy chest trauma. For this reason, the US increases the accuracy of diagnosis in minor chest traumas and rib fractures and decreases the repetitive referral of patients to health institutions by reducing the missed diagnosis.Keywords: Rib fractures, thoracic injuries, trauma, ultrasonography, radiography
简介:钝性胸部外伤最常见的损伤是肋骨骨折(25%),通常在x线片上可见。然而,x光片有时无法显示骨折,特别是软骨骨折,除非它们密集钙化。本研究旨在探讨超声(US)在检测轻度钝性胸部创伤的肋骨骨折中的作用,并将其与后路胸片(PA)的成功率进行比较。方法:纳入2017年6月至2019年3月期间接受过US和x线检查以评估疑似肋骨骨折的轻微钝性胸部创伤患者。在PA投影中获得x线片。US是由一位放射科医生进行的,他通过US上肋骨前缘的破坏确定了骨折。然后比较超声和x线摄影检测到的骨折发生率和位置。结果:共纳入126例患者。98名患者(78%)为首次入院,28名患者(22%)为第二次入院(他们之前曾在其他医院入院,并通过x线摄影评估为“正常”)。通过x线摄影和超声检查共发现108例骨折(79例患者(63%)),而47例患者(37%)没有骨折的诊断证据。所有骨折超声检出率均为100%,而x线片检出率为16例(14.81%)。通过x线摄影和超声诊断的患者在诊断能力上有统计学意义的差异(p=0.001)。结论:超声对肋骨骨折的诊断准确性明显优于x线摄影。无论创伤部位、定位和位置如何,超声都明显优于x线摄影。尽管一些肋骨区域在超声评估中无法到达,但当涉及到轻微的胸部能量损伤时,超声快速评估受影响最大的区域是最有效的。因此,美国提高了轻微胸部创伤和肋骨骨折的诊断准确性,通过减少漏诊,减少了患者反复转诊到卫生机构的次数。关键词:肋骨骨折,胸椎损伤,创伤,超声,影像学
{"title":"Minör göğüs travmasında radyografinin kaburga kırıklarını tanımada yeterliliği: Sonografi ve radyografinin etkinlik kıyaslaması","authors":"Emre Yurdakul, Servet Kahveci̇","doi":"10.22391/fppc.1033620","DOIUrl":"https://doi.org/10.22391/fppc.1033620","url":null,"abstract":"Introduction: The most common injury resulting from blunt chest trauma is a rib fracture (25%) which is usually visible on radiographs. However, radiographs sometimes cannot show fractures, especially those in cartilage, unless they're densely calcified. The present study aimed to investigate the role of ultrasonography (US) in detecting rib fractures with minor blunt chest trauma and comparing its success with posteroanterior (PA) chest radiography.Methods: Patients with minor blunt chest trauma who had previously undergone US and radiography to assess suspected rib fractures, between June 2017– March 2019, were included. Radiography was obtained in the PA projection. US was performed by a radiologist who identified fractures by the disruption of the anterior margin of the rib on the US. The incidence and location of the fractures detected by US and radiography were then compared.Results: Totally 126 patients were included in the study. Ninety-eight patients (78%) were admitted to the hospital for the first time, and 28 patients (22%) for the second time (they previously admitted to the other hospitals and were evaluated as ‘normal’ by radiography). A total of 108 fractures ( in 79 patients (63%) ) were detected based on radiography and US examination, while 47 patients (37%) had no diagnostic evidence of fracture. All fractures were correctly detected by ultrasonography (100%), whereas radiography revealed 16 fractures (14.81%). A statistically significant difference in diagnostic capability was found between patients diagnosed by radiography and US (p=0.001).Conclusion: Ultrasonographic imaging is significantly superior to radiography in terms of accuracy in diagnosing rib fractures. Ultrasound was found to be significantly superior to radiography regardless of trauma site, localization, and location. Even though some rib areas are inaccessible on ultrasonographic evaluation, rapid evaluation of the most affected areas is most effective with ultrasonography when it comes to minor energy chest trauma. For this reason, the US increases the accuracy of diagnosis in minor chest traumas and rib fractures and decreases the repetitive referral of patients to health institutions by reducing the missed diagnosis.Keywords: Rib fractures, thoracic injuries, trauma, ultrasonography, radiography","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47146675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SIRS tanılı hastalarda enflamasyon ve kemik döngüsü arasındaki ilişkinin sklerostin ve Dickkopf-1 (DKK-1) düzeyleri ile değerlendirilmesi
Pub Date : 2022-07-31 DOI: 10.22391/fppc.1102573
Hatice Betül Altınışık, Uğur Altınışık, Mehmet Aşık
Introduction: In intensive care units (ICU), patients remain bedridden for a long time. In addition, severe infections are frequently seen in ICUs. Both prolonged immobilization and serious infections are associated with bone tissue loss. The Wnt pathway has recently been focused on evaluating bone tissue loss. The Wnt pathway participates in both infections and the formation of bone tissue. Wnt pathway inhibitors sclerostin and Dickkopf-1 (DKK-1) inhibit bone formation and increase osteoclastic activity. In this study, we aimed to examine bone turnover by the Wnt inhibitors sclerostin and DKK-1 and their possible associations with inflammation in SIRS patients.Methods: We included 30 patients diagnosed with systemic inflammatory response syndrome (SIRS) in the study group and 16 in the control group. Serum sclerostin, DKK-1, white blood cell (WBC), and C-Reactive Protein (CRP) levels on the day of SIRS diagnosis (basal), the 7th, 14th, and 21stdays were evaluated in the study group, and the results were compared with the control group.Results: When the control group was compared with the basal SIRS, there was a significant elevation in both sclerostin (p=0.003) and DKK-1 (p=0.001). Statistical analysis showed significant decreases in sclerostin levels between basal and the 7th, 14th, and 21st days (p=0.033, p=0.003, p=0.002, respectively). Similarly, significant decreases in DKK-1 levels between basal and the 7th and 21st days (p=0.015, p=0.001, respectively) and an insignificant decrease on the 14th day (p=0.191) was observed. Sclerostin was positively and significantly correlated with WBC and CRP in basal and 7th-day measurements and WBC in 7th and 14th days. DKK-1 is positively and significantly correlated with WBC in basal and 7th-daymeasurements, while DKK-1 negatively correlates with CRP in basal-7th-day measurements.Conclusion: In this study, it was shown for the first time that the Wnt antagonists sclerostin and DKK-1 values are high in SIRS patients in ICU. Both biomarker levels decreased in parallel with the treatment. However, it could not be associated with disease severity and inflammatory marker levels. We believe that monitoring the change of Wnt antagonists will be useful in demonstrating bone turnover in patients with SIRS.Keywords: Dickkopf-1, Intensive care unit, Sclerostin, Systemic inflammatory response syndrome, Wnt signaling pathway, Bone turnover                        
在重症监护病房(ICU),病人长期卧床不起。此外,重症监护室经常出现严重感染。长期固定和严重感染都与骨组织丢失有关。Wnt通路最近被关注于评估骨组织损失。Wnt通路参与感染和骨组织的形成。Wnt通路抑制剂sclerostin和Dickkopf-1 (DKK-1)抑制骨形成并增加破骨细胞活性。在这项研究中,我们旨在研究Wnt抑制剂sclerostin和DKK-1在SIRS患者中的骨转换及其与炎症的可能关联。方法:我们将30例诊断为全身性炎症反应综合征(SIRS)的患者作为研究组,16例为对照组。测定研究组患者在SIRS诊断当天(基础)、第7、14、21天的血清硬化蛋白(sclerostin)、DKK-1、白细胞(WBC)、c反应蛋白(CRP)水平,并与对照组进行比较。结果:当对照组与基础SIRS比较时,硬化蛋白(p=0.003)和DKK-1 (p=0.001)均显著升高。统计分析显示,在基础和第7、14、21天,硬化蛋白水平显著降低(p=0.033, p=0.003, p=0.002)。DKK-1水平在试验第7天和第21天显著降低(p=0.015, p=0.001),第14天显著降低(p=0.191)。硬化蛋白与基础和第7天的WBC和CRP以及第7和第14天的WBC呈正相关。DKK-1与基础和第7天的WBC呈正相关,而DKK-1与第7天的CRP呈负相关。结论:本研究首次发现ICU SIRS患者Wnt拮抗剂sclerostin和DKK-1值较高。这两种生物标志物水平在治疗过程中同时下降。然而,它与疾病严重程度和炎症标志物水平无关。我们相信监测Wnt拮抗剂的变化将有助于证明SIRS患者的骨转换。关键词:Dickkopf-1,重症监护病房,Sclerostin,全身炎症反应综合征,Wnt信号通路,骨转换
{"title":"SIRS tanılı hastalarda enflamasyon ve kemik döngüsü arasındaki ilişkinin sklerostin ve Dickkopf-1 (DKK-1) düzeyleri ile değerlendirilmesi","authors":"Hatice Betül Altınışık, Uğur Altınışık, Mehmet Aşık","doi":"10.22391/fppc.1102573","DOIUrl":"https://doi.org/10.22391/fppc.1102573","url":null,"abstract":"Introduction: In intensive care units (ICU), patients remain bedridden for a long time. In addition, severe infections are frequently seen in ICUs. Both prolonged immobilization and serious infections are associated with bone tissue loss. The Wnt pathway has recently been focused on evaluating bone tissue loss. The Wnt pathway participates in both infections and the formation of bone tissue. Wnt pathway inhibitors sclerostin and Dickkopf-1 (DKK-1) inhibit bone formation and increase osteoclastic activity. In this study, we aimed to examine bone turnover by the Wnt inhibitors sclerostin and DKK-1 and their possible associations with inflammation in SIRS patients.Methods: We included 30 patients diagnosed with systemic inflammatory response syndrome (SIRS) in the study group and 16 in the control group. Serum sclerostin, DKK-1, white blood cell (WBC), and C-Reactive Protein (CRP) levels on the day of SIRS diagnosis (basal), the 7th, 14th, and 21stdays were evaluated in the study group, and the results were compared with the control group.Results: When the control group was compared with the basal SIRS, there was a significant elevation in both sclerostin (p=0.003) and DKK-1 (p=0.001). Statistical analysis showed significant decreases in sclerostin levels between basal and the 7th, 14th, and 21st days (p=0.033, p=0.003, p=0.002, respectively). Similarly, significant decreases in DKK-1 levels between basal and the 7th and 21st days (p=0.015, p=0.001, respectively) and an insignificant decrease on the 14th day (p=0.191) was observed. Sclerostin was positively and significantly correlated with WBC and CRP in basal and 7th-day measurements and WBC in 7th and 14th days. DKK-1 is positively and significantly correlated with WBC in basal and 7th-daymeasurements, while DKK-1 negatively correlates with CRP in basal-7th-day measurements.Conclusion: In this study, it was shown for the first time that the Wnt antagonists sclerostin and DKK-1 values are high in SIRS patients in ICU. Both biomarker levels decreased in parallel with the treatment. However, it could not be associated with disease severity and inflammatory marker levels. We believe that monitoring the change of Wnt antagonists will be useful in demonstrating bone turnover in patients with SIRS.Keywords: Dickkopf-1, Intensive care unit, Sclerostin, Systemic inflammatory response syndrome, Wnt signaling pathway, Bone turnover                        ","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41565660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
İnflamatuvar barsak hastalığı olan hastalarda klinik özellikler, tedavi seçenekleri ve komplikasyonların değerlendirilmesi
Pub Date : 2022-07-31 DOI: 10.22391/fppc.1088562
Mücahit Ugar, Fatih Kamiş, Yavuz Beyazit
Introduction: Inflammatory bowel diseases (IBD) form a group of inflammatory diseases occurring in genetically-susceptible people, which are characterized by chronic progression and whose cause is not fully known. The aim of this study is to determine the incidence of IBD in our region and examine the clinical characteristics, sociodemographic features, and treatment results of IBD patients.Methods: Our study retrospectively investigates 211 patients over 18 years of age who were monitored for an IBD diagnosis between January 2, 2013, and December 31, 2019, by the gastroenterology department of Canakkale Onsekiz Mart University’s Faculty of Medicine. The mean age, female-male ratio, smoking habits, disease severity, and localization sites were identified for included patients. Local and systemic complications of administered treatment types and reasons for surgical treatment were also assessed in patients.Results: Of the 211 patients with IBD diagnoses, 158 (74.9%) had Ulcerative Colitis (UC) and 53 (25.1%) had a diagnosis of Crohn’s disease (CD). The mean age at the time of diagnosis was 43.97±16.22 years for UC patients and 42.30±14.73 years for CD cases. The involvement sites for UC were distal colitis for 58.4% of patients, left colon for 24.1% of patients, pancolitis for 16.5% of patients, and backwash ileitis for 7% of patients. According to the treatment results, 152 (72.0%) patients took 5-aminosalicylate (5-ASA) alone, 48 (22.8%) took thiopurine, and 20 (9.5%) took anti-TNF.Conclusion: Knowing the demographic, clinical, and laboratory features of these diseases, which are frequently seen in our region, can support the early identification of probable complications that may occur and the selection of appropriate approaches during diagnosis, treatment, and follow-up monitoring of these diseases.Keywords: Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn’s Disease, Severity of Illness Index, Abdominal Pain, Diarrhea
引言:炎症性肠病(IBD)是一组发生在遗传易感人群中的炎症性疾病,其特征是慢性进展,其病因尚不完全清楚。本研究的目的是确定我们地区IBD的发病率,并检查IBD患者的临床特征、社会人口学特征和治疗结果。方法:我们的研究回顾性调查了2013年1月2日至2019年12月31日期间由卡纳卡莱-昂塞基兹-马尔特大学医学院胃肠科监测的211名18岁以上的IBD诊断患者。确定纳入患者的平均年龄、男女比例、吸烟习惯、疾病严重程度和定位部位。还评估了患者的局部和全身并发症的给药治疗类型以及手术治疗的原因。结果:在211名诊断为IBD的患者中,158名(74.9%)患有溃疡性结肠炎(UC),53名(25.1%)诊断为克罗恩病(CD)。UC患者诊断时的平均年龄为43.97±16.22岁,CD患者诊断时为42.30±14.73岁。UC的受累部位为58.4%的患者的远端结肠炎,24.1%的患者的左结肠,16.5%的患者为全结肠炎,7%的患者为反冲洗性回肠炎。根据治疗结果,152名(72.0%)患者单独服用5-氨基水杨酸(5-ASA),48名(22.8%)患者服用硫嘌呤,20名(9.5%)患者服用抗TNF,可以支持早期识别可能发生的并发症,并在诊断、治疗和后续监测这些疾病期间选择适当的方法。关键词:炎症性肠病、溃疡性结肠炎、克罗恩病、疾病严重程度指数、腹痛、腹泻
{"title":"İnflamatuvar barsak hastalığı olan hastalarda klinik özellikler, tedavi seçenekleri ve komplikasyonların değerlendirilmesi","authors":"Mücahit Ugar, Fatih Kamiş, Yavuz Beyazit","doi":"10.22391/fppc.1088562","DOIUrl":"https://doi.org/10.22391/fppc.1088562","url":null,"abstract":"Introduction: Inflammatory bowel diseases (IBD) form a group of inflammatory diseases occurring in genetically-susceptible people, which are characterized by chronic progression and whose cause is not fully known. The aim of this study is to determine the incidence of IBD in our region and examine the clinical characteristics, sociodemographic features, and treatment results of IBD patients.Methods: Our study retrospectively investigates 211 patients over 18 years of age who were monitored for an IBD diagnosis between January 2, 2013, and December 31, 2019, by the gastroenterology department of Canakkale Onsekiz Mart University’s Faculty of Medicine. The mean age, female-male ratio, smoking habits, disease severity, and localization sites were identified for included patients. Local and systemic complications of administered treatment types and reasons for surgical treatment were also assessed in patients.Results: Of the 211 patients with IBD diagnoses, 158 (74.9%) had Ulcerative Colitis (UC) and 53 (25.1%) had a diagnosis of Crohn’s disease (CD). The mean age at the time of diagnosis was 43.97±16.22 years for UC patients and 42.30±14.73 years for CD cases. The involvement sites for UC were distal colitis for 58.4% of patients, left colon for 24.1% of patients, pancolitis for 16.5% of patients, and backwash ileitis for 7% of patients. According to the treatment results, 152 (72.0%) patients took 5-aminosalicylate (5-ASA) alone, 48 (22.8%) took thiopurine, and 20 (9.5%) took anti-TNF.Conclusion: Knowing the demographic, clinical, and laboratory features of these diseases, which are frequently seen in our region, can support the early identification of probable complications that may occur and the selection of appropriate approaches during diagnosis, treatment, and follow-up monitoring of these diseases.Keywords: Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn’s Disease, Severity of Illness Index, Abdominal Pain, Diarrhea","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43308365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19 hastalarının semptomlarına ve pnömoni varlığına göre antikor tepkileri
Pub Date : 2022-05-31 DOI: 10.22391/fppc.1049314
Ramazan Korkusuz, Faruk Karandere
Introduction: The aim of the study was to examine the 30-day total SARS-CoV-2 antibody positivity in patients across a clinical spectrum ranging from asymptomatic to pneumonia.Methods: This prospective cohort study consisted of 51 consecutive patients who were RT-PCR positive and diagnosed COVID-19 pneumonia (Group 1) and 58 consecutive patients who were also RT-PCR positive but were asymptomatic or had mild symptoms (Group 2). On the 30th day from the date of symptom onset, the patients were called for examination and blood samples were taken for the detection of SARS-CoV-2 antibodies.Results: Patients with pneumonia, fever, muscle pain, and loss of taste and smell had significantly higher rates of antibody positivity (p= 0.001, 0.003, 0.030, and 0.018, respectively). Antibody positivity was found to be significantly higher in patients with at least one symptom on admission compared to asymptomatic patients (p = 0.001). While the antibody positivity rate was 96.1% in Group 1 (patients with pneumonia), it was 50% in Group 2 (patients without pneumonia), and 77.7% in patients with at least one symptom on admission compared to 33.3% in asymptomatic patients (p=0.001).Conclusions: Patients with COVID-19 pneumonia have significantly higher disease-specific total antibody positivity rates than patients without pneumonia. Considering the 50% antibody positivity in patients who had COVID-19 infection who were asymptomatic or had symptoms other than pneumonia, the issue of COVID-19 re-infection and immunity is much more important than it appears. 
该研究的目的是检查从无症状到肺炎的临床谱患者的30天总SARS-CoV-2抗体阳性情况。方法:本前瞻性队列研究包括连续51例RT-PCR阳性诊断为COVID-19肺炎的患者(第一组)和连续58例RT-PCR阳性但无症状或症状轻微的患者(第二组)。自症状出现之日起第30天,对患者进行检查并采集血液检测SARS-CoV-2抗体。结果:肺炎、发热、肌肉疼痛、味觉和嗅觉丧失患者的抗体阳性率明显高于对照组(p分别为0.001、0.003、0.030和0.018)。与无症状患者相比,入院时至少有一种症状的患者抗体阳性明显更高(p = 0.001)。1组(肺炎患者)抗体阳性率为96.1%,2组(无肺炎患者)抗体阳性率为50%,入院时至少有一种症状的患者抗体阳性率为77.7%,而无症状患者抗体阳性率为33.3% (p=0.001)。结论:COVID-19肺炎患者的疾病特异性总抗体阳性率明显高于非肺炎患者。在无症状或非肺炎症状的新冠肺炎感染者中,抗体阳性率高达50%,因此再次感染和免疫问题比表面上更重要。
{"title":"COVID-19 hastalarının semptomlarına ve pnömoni varlığına göre antikor tepkileri","authors":"Ramazan Korkusuz, Faruk Karandere","doi":"10.22391/fppc.1049314","DOIUrl":"https://doi.org/10.22391/fppc.1049314","url":null,"abstract":"Introduction: The aim of the study was to examine the 30-day total SARS-CoV-2 antibody positivity in patients across a clinical spectrum ranging from asymptomatic to pneumonia.Methods: This prospective cohort study consisted of 51 consecutive patients who were RT-PCR positive and diagnosed COVID-19 pneumonia (Group 1) and 58 consecutive patients who were also RT-PCR positive but were asymptomatic or had mild symptoms (Group 2). On the 30th day from the date of symptom onset, the patients were called for examination and blood samples were taken for the detection of SARS-CoV-2 antibodies.Results: Patients with pneumonia, fever, muscle pain, and loss of taste and smell had significantly higher rates of antibody positivity (p= 0.001, 0.003, 0.030, and 0.018, respectively). Antibody positivity was found to be significantly higher in patients with at least one symptom on admission compared to asymptomatic patients (p = 0.001). While the antibody positivity rate was 96.1% in Group 1 (patients with pneumonia), it was 50% in Group 2 (patients without pneumonia), and 77.7% in patients with at least one symptom on admission compared to 33.3% in asymptomatic patients (p=0.001).Conclusions: Patients with COVID-19 pneumonia have significantly higher disease-specific total antibody positivity rates than patients without pneumonia. Considering the 50% antibody positivity in patients who had COVID-19 infection who were asymptomatic or had symptoms other than pneumonia, the issue of COVID-19 re-infection and immunity is much more important than it appears. ","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43421918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bir çocukta ön diz ağrısının nadir bir nedeni: Patellar Osteoid Osteoma ve literatürün gözden geçirilmesi 儿童膝关节疼痛的一个罕见原因是通过骨样骨瘤和文献检测髌骨。
Pub Date : 2022-05-31 DOI: 10.22391/fppc.1065332
Nazan Kaymaz, Burak Kaymaz
Giriş: Osteoid Osteoma (OO) belirgin bir nidus ve onu çevreleyen sklerotik reaktif zon ile karakterize küçük selim bir kemik tümörüdür. Genellikle uzun kemiklerde yerleşmekle birlikte nadiren patellada da görülebilmektedir.Vaka Sunumu: Sekiz yaşında kız çocuğu ön diz ağrısı şikayetiyle polikliniğimize başvurdu. Hastanın ağrı şikayetleri yaklaşık bir yıldır mevcuttu. Hastada Patellar Osteoid Osteoma tespit edildi. Lezyon kürete edildi ve cerrahi sonrası ilk gün hastanın ağrıları tamamen geçti.Sonuç: Her ne kadar Patellar OO nadir gözükse de çocuk ve genç erişkinlerdeki uzun süreli diz ağrısının ayırıcı tanısında düşünülmesi gerekir.Anahtar Kelimeler: Osteoid Osteoma, patella, diz ağrısı, küretaj, gecikmiş tanı, kemik neoplazmı
条目:类骨骨瘤(OO)是一种特殊的细胞核,是一种小而平和的骨肿瘤,周围有硬化反应区。通常,它与长骨一起出现在罕见的专利中。介绍:八岁时,女孩申请了我们的膝前疼痛投诉。病人的疼痛抱怨已经持续了将近一年。髌骨类骨性骨瘤已在医院确认。在手术的第一天之后,患者的疼痛已经完全消除。因此,无论髌骨OO出现得多么罕见,它都必须被认为是儿童和年轻人长期膝盖疼痛的隔离物。关键词:骨样骨瘤,髌骨,膝关节疼痛,曲度,晚期发现,骨肿瘤
{"title":"Bir çocukta ön diz ağrısının nadir bir nedeni: Patellar Osteoid Osteoma ve literatürün gözden geçirilmesi","authors":"Nazan Kaymaz, Burak Kaymaz","doi":"10.22391/fppc.1065332","DOIUrl":"https://doi.org/10.22391/fppc.1065332","url":null,"abstract":"Giriş: Osteoid Osteoma (OO) belirgin bir nidus ve onu çevreleyen sklerotik reaktif zon ile karakterize küçük selim bir kemik tümörüdür. Genellikle uzun kemiklerde yerleşmekle birlikte nadiren patellada da görülebilmektedir.Vaka Sunumu: Sekiz yaşında kız çocuğu ön diz ağrısı şikayetiyle polikliniğimize başvurdu. Hastanın ağrı şikayetleri yaklaşık bir yıldır mevcuttu. Hastada Patellar Osteoid Osteoma tespit edildi. Lezyon kürete edildi ve cerrahi sonrası ilk gün hastanın ağrıları tamamen geçti.Sonuç: Her ne kadar Patellar OO nadir gözükse de çocuk ve genç erişkinlerdeki uzun süreli diz ağrısının ayırıcı tanısında düşünülmesi gerekir.Anahtar Kelimeler: Osteoid Osteoma, patella, diz ağrısı, küretaj, gecikmiş tanı, kemik neoplazmı","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45087979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Family Practice and Palliative Care
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1