Introduction: The Google search engine is a widely used resource for accessing health-related patient education texts. Therefore accessible information in the texts should be accurate, up-to-date and appropriate to the general public health literacy level. In this research, we aimed to analyze the readability of patient education texts prepared for breast cancer presented on internet and to evaluate the content of texts.Methods:A total of 200 web sites at Google search engine were evaluated using the terms “breast cancer and breast mass”. The average readability level was analyzed using Atesman and Bezirci-Yilmaz readability formulas. The texts were also evaluated in terms of the risk factors identified in the development of breast cancer, the presence of examination and screening methods that could be used in early diagnosis.Results:A total 64 internet sites that are in compliance with the research criteria were evaluated. The overall mean reading level of the texts was found moderate, using the Atesman formula and college level according to Bezirci. 18 Web sites had both the risk factors identified in the development of breast cancer and the methods of screenings.Conclusions: A total 64 internet sites that are in compliance with the research criteria were evaluated. The overall mean reading level of the texts was found moderate, using the Atesman formula and college level according to Bezirci. 18 Web sites had both the risk factors identified in the development of breast cancer and the methods of screenings.
{"title":"İnternet ortamındaki meme kanseri ile ilgili hasta eğitim materyallerinin okunabilirliğinin değerlendirilmesi","authors":"N. Aksoy, B. Kozanhan, M. Eryılmaz, M. Tutar","doi":"10.22391/FPPC.480193","DOIUrl":"https://doi.org/10.22391/FPPC.480193","url":null,"abstract":"Introduction: The Google search engine\u0000is a widely used resource for accessing health-related patient education texts.\u0000Therefore accessible information in the texts should be accurate, up-to-date\u0000and appropriate to the general public health literacy level. In this research,\u0000we aimed to analyze the readability of patient education texts prepared for\u0000breast cancer presented on internet and to evaluate the content of texts.Methods:A total of 200 web sites\u0000at Google search engine were evaluated using the terms “breast cancer and breast mass”. The average\u0000readability level was analyzed using Atesman and Bezirci-Yilmaz readability formulas.\u0000The texts were also evaluated in terms of the risk factors identified in the\u0000development of breast cancer, the presence of examination and screening methods\u0000that could be used in early diagnosis.Results:A total 64 internet sites\u0000that are in compliance with the research criteria were evaluated. The overall\u0000mean reading level of the texts was found moderate, using the Atesman formula\u0000and college level according to Bezirci. 18 Web sites had both the risk factors\u0000identified in the development of breast cancer and the methods of screenings.Conclusions: A\u0000total 64 internet sites that are in compliance with the research criteria were\u0000evaluated. The overall mean reading level of the texts was found moderate,\u0000using the Atesman formula and college level according to Bezirci. 18 Web sites\u0000had both the risk factors identified in the development of breast cancer and\u0000the methods of screenings.","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48618987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ö. Karaaslan, Ç. Kantekin, Y. Hacımusalar, G. Talih
Introduction: Health anxiety is the excessively negative interpretation of normal physical signs in an individual with no physical disease. Having knowledge information about the health anxiety levels of patients is one of the criteria that will affect the treatment of the patients’ pain. The aim of this study was to evaluate the preoperative health anxiety of laparoscopic cholecystectomy patients together with the perception of postoperative pain and the requirement for analgesia.Methods: The study included 41 patients of American Society of Anesthesiologists(ASA) grade I-II, aged 18-65 years who were to undergo a laparoscopic cholecystectomy operation and a control group of 40 healthy individuals. The Health Anxiety Inventory was applied to the patients preoperatively and to the control group. In the postoperative period, the patients were followed up for 24 hours with a patient-controlled analgesia device prepared with tramadol. Visuel Analog Scale(VAS) values of patients were below 4 due to the use of patient controlled analgesia device. Total analgesic consumption was recorded. The results were compared statistically.Results: No significant difference was determined between the patient and control groups in respect of age, gender and body mass index (p>0.05). The VAS score of all the patients was less than four. The mean total tramadol consumption of the patients in the first 24 hours postoperatively was 221.58±73.06. The analgesia consumption of female patients was significantly higher than that of males (p=0.013). The health anxiety results of the patient group were found to be significantly higher than the control group (p<0.001). A positive correlation was determined in the patient group between health anxiety and the total analgesia requirement (r=0.813, p<0.01). Conclusions: In conclusion, high level of analgesia consumption was determined in those with high health anxiety and in female patients. When planning postoperative pain treatment, consideration of the gender of the patient and the level of health anxiety will make a positive contribution to the treatment.
{"title":"The effect of health anxiety on postoperative analgesia requirement and anesthesia recovery in patients undergoing laparoscopic cholecystectomy","authors":"Ö. Karaaslan, Ç. Kantekin, Y. Hacımusalar, G. Talih","doi":"10.22391/fppc.435395","DOIUrl":"https://doi.org/10.22391/fppc.435395","url":null,"abstract":"Introduction: Health anxiety is the excessively negative interpretation of normal\u0000physical signs in an individual with no physical disease. Having knowledge\u0000information about the health anxiety levels of patients is one of the criteria\u0000that will affect the treatment of the patients’ pain. The aim of this study was\u0000to evaluate the preoperative health anxiety of laparoscopic cholecystectomy\u0000patients together with the perception of postoperative pain and the requirement\u0000for analgesia.Methods: The\u0000study included 41 patients of American Society of Anesthesiologists(ASA) grade\u0000I-II, aged 18-65 years who were to undergo a laparoscopic cholecystectomy\u0000operation and a control group of 40 healthy individuals. The Health Anxiety\u0000Inventory was applied to the patients preoperatively and to the control group.\u0000In the postoperative period, the patients were followed up for 24 hours with a\u0000patient-controlled analgesia device prepared with tramadol. Visuel Analog\u0000Scale(VAS) values of patients were below 4 due to the use of patient controlled\u0000analgesia device. Total analgesic consumption was recorded. The results were compared\u0000statistically.Results: No significant difference was determined between the patient and control\u0000groups in respect of age, gender and body mass index (p>0.05). The VAS score\u0000of all the patients was less than four. The mean total tramadol consumption of\u0000the patients in the first 24 hours postoperatively was 221.58±73.06. The\u0000analgesia consumption of female patients was significantly higher than that of\u0000males (p=0.013). The health anxiety results of the patient group were found to\u0000be significantly higher than the control group (p<0.001). A positive\u0000correlation was determined in the patient group between health anxiety and the\u0000total analgesia requirement (r=0.813, p<0.01).\u0000\u0000\u0000\u0000\u0000\u0000Conclusions: In conclusion, high level of analgesia consumption was determined in\u0000those with high health anxiety and in female patients. When planning\u0000postoperative pain treatment, consideration of the gender of the patient and\u0000the level of health anxiety will make a positive contribution to the treatment.","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":"4 1","pages":"7-10"},"PeriodicalIF":0.0,"publicationDate":"2019-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68403522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Akut viral gastroenteritlerde oral çinko kullanımının hastalığın semptomları ve süresine etkisinin değerlendirilmesi","authors":"Çiğdem El, Mehmet Çeli̇kkaya","doi":"10.22391/fppc.471460","DOIUrl":"https://doi.org/10.22391/fppc.471460","url":null,"abstract":"","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68403889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ibrahim Solak, D. Yıldırım, Mustafa Solak, Ç. Çetinkaya, A. Boyaci, M. Eryılmaz
{"title":"Serum netrin-1 seviyesinin meme kitleleriyle ilişkisi","authors":"Ibrahim Solak, D. Yıldırım, Mustafa Solak, Ç. Çetinkaya, A. Boyaci, M. Eryılmaz","doi":"10.22391/fppc.467700","DOIUrl":"https://doi.org/10.22391/fppc.467700","url":null,"abstract":"","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68403557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giris : Bu calismanin amaci, Aile Hekimligi poliklinigine farkli nedenlerle basvuran, 0-7 yas arasi cocuga sahip annelerinin ates konusundaki bilgilerinin ve ates karsisindaki tutumlarinin belirlenmesi, bunlari etkileyen faktorlerin incelenmesidir. Yontem : Calisma, Dumlupinar Universitesi Evliya Celebi Hastanesi Aile Hekimligi Poliklinigi’ne basvuran 112 anne ile yapildi. Veriler coktan secmeli sorulardan olusan anket formu ile toplandi ve degerlendirildi. Bulgular : Annelerin yas ortalamasi 31 ± 5,3 yil idi. Egitim durumuna gore 68’i (%60,7) ilkogretim, 30’u (%26,7) lise ve 14’u (%12,5) ise universite mezunu idi. Annelerin sahip oldugu cocuk sayisi ortalama 3±1,7 idi. Katilimcilarin, 73’unun evinde isiolcer vardi, fakat isiolceri bulunsa da annelerin 53’u (%47,3) atesi dokunarak, 13’u genel durumuna bakarak anlamaktaydi. Otuz uc anne (%29,4) derece kullanarak ates olctugunu ifade etti. Yetmis bes (%67) anne vucut sicakligini olcmeyi bildigini soylese de, nasil olcum yaptiklari soruldugunda yalnizca 18’i (%16) tam ve dogru olcumun nasil yapildigini anlatabildi. Termometre kullanmayi bildigini soyleyen annelerin 17’si (%22,6) termometrenin olcum alaninda tutulmasi gereken sureden daha az, 29’u (%38,6) ise daha fazla bir surede tutulmasi gerektigini soylemislerdir. Olcum yerlerine gore, annelerin 88’i (%78,5) vucut sicakligini koltuk alti bolgesinden olcmekteydi. Bunu sirasiyla timpanik, oral ve daha kucuk cocuklarda rektal olcumler izliyordu. Sonuc : Sonuc olarak; annelerin genellikle ates olcum yeri, suresi ve sekli ile ilgili yanlis veya eksik bilgiye sahip oldugu gozlenmistir. Ayrica, annelerin egitim duzeyi yukseldikce ates korkusunun azaldigi da tespit edildi.
条目：这场灾难的目的是研究数据对0-7岁可卡因父母的死亡和状况的影响，这些数据因不同原因适用于家庭Hekimligi。Yontem：Calisma，Dumlupinar大学Evliya Celebi Hastanesi Aile Hekimligi Poliklinigii ne basvuran 112 anne ile yapildi。如果你已经在问问题，数据会被收集并用问卷表降级。研究结果显示，母亲的强度为31±5.3岁。事实上，68年前（60.7）大学毕业，30年前（26.7）和14年前（12.5）大学毕业。我们母亲的平均鸡数为3±1.7只。暗杀者当时住在73人的房子里，但当他们发现劫机者时，从他们13人的总体状况来看，他们通过触火了解了母亲的53%（47.3%）。30个手指的母亲（29.4）表达了马的年龄。七年级（67岁）的学生说，这位母亲知道如何签订合同，当被问及如何签订合同时，只签订了18（16）份。他们说，17名知道如何使用体温计的母亲（22.6名）应该在体温计的嗅觉区域被捕，不到29名（38.6名）的母亲应该在更多的图像中被捕。Olcum yerlerine gore，annelerin 88’i（%78,5）vucut sicakligini koltuk alti bolgesinden olcmekteydi。这是一个很好的例子。因此母亲们通常对火灾的地点、面部和斧头有虚假或缺乏了解。此外，当我母亲的蔬菜淋浴被取消时，对火灾的恐惧也减少了。
{"title":"Ateşli çocuklarda, annelerin bilgi düzeyleri ve ateşe yaklaşımları","authors":"Yasemin Korkut","doi":"10.22391/fppc.370931","DOIUrl":"https://doi.org/10.22391/fppc.370931","url":null,"abstract":"Giris : Bu calismanin amaci, Aile Hekimligi poliklinigine farkli nedenlerle basvuran, 0-7 yas arasi cocuga sahip annelerinin ates konusundaki bilgilerinin ve ates karsisindaki tutumlarinin belirlenmesi, bunlari etkileyen faktorlerin incelenmesidir. Yontem : Calisma, Dumlupinar Universitesi Evliya Celebi Hastanesi Aile Hekimligi Poliklinigi’ne basvuran 112 anne ile yapildi. Veriler coktan secmeli sorulardan olusan anket formu ile toplandi ve degerlendirildi. Bulgular : Annelerin yas ortalamasi 31 ± 5,3 yil idi. Egitim durumuna gore 68’i (%60,7) ilkogretim, 30’u (%26,7) lise ve 14’u (%12,5) ise universite mezunu idi. Annelerin sahip oldugu cocuk sayisi ortalama 3±1,7 idi. Katilimcilarin, 73’unun evinde isiolcer vardi, fakat isiolceri bulunsa da annelerin 53’u (%47,3) atesi dokunarak, 13’u genel durumuna bakarak anlamaktaydi. Otuz uc anne (%29,4) derece kullanarak ates olctugunu ifade etti. Yetmis bes (%67) anne vucut sicakligini olcmeyi bildigini soylese de, nasil olcum yaptiklari soruldugunda yalnizca 18’i (%16) tam ve dogru olcumun nasil yapildigini anlatabildi. Termometre kullanmayi bildigini soyleyen annelerin 17’si (%22,6) termometrenin olcum alaninda tutulmasi gereken sureden daha az, 29’u (%38,6) ise daha fazla bir surede tutulmasi gerektigini soylemislerdir. Olcum yerlerine gore, annelerin 88’i (%78,5) vucut sicakligini koltuk alti bolgesinden olcmekteydi. Bunu sirasiyla timpanik, oral ve daha kucuk cocuklarda rektal olcumler izliyordu. Sonuc : Sonuc olarak; annelerin genellikle ates olcum yeri, suresi ve sekli ile ilgili yanlis veya eksik bilgiye sahip oldugu gozlenmistir. Ayrica, annelerin egitim duzeyi yukseldikce ates korkusunun azaldigi da tespit edildi.","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68403449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ibrahim Solak, Kamile Marakoğlu, Selma Pekgor, Nisa Çetin Kargın, Y. T. Gederet, Necat Alataş, M. Eryılmaz
Giris : Bu calismada, sigara birakma sonrasi, hem sistemik inflamasyonda hem de nasal mukosilier klirensde meydana gelen degisiklikleri ve bunlarin sigara icme ozellikleri ile iliskilerinin degerlendirilmesi amaclanmistir. Yontem : Saglik Bilimleri Universitesi Konya Egitim Arastirma Hastanesi Sigara Birakma Poliklinigine basvuran 30 vaka calismaya dahil edilip 27 vaka ile calisma tamamlanmistir. Tumor nekrozis faktor-alfa (TNF-α), interlokin (IL) -4, IL-6, IL-8, IL-10 ve sakarin gecis suresi (STT), kayit ve sigara birakilmasindan 2 ay sonra olculdu. Bulgular : Bu calismada, STT’nin sigara birakildiktan 2 ay sonra anlamli olarak kisaldigi goruldu (p <0,001). Serum TNF-α (p = 0,035) ve IL-8 (p = 0,002) duzeylerinin, bazal seviyelerle karsilastirildiginda, sigara biraktiktan sonraki 2. ayda anlamli olarak azaldigini bulduk. Bazal seviyelerle karsilastirildiginda, sigara biraktiktan sonraki 2. ayda serum IL-6 (p = 0,132) ve IL-10 (p = 0,657) seviyelerinin degisiminin anlamli olmadigi gozlendi. Sonuc : Sigara birakma isleminden iki ay sonra, nazal mukosiliyer klirens ve sistemik inflamatuar yanitta, ozellikle plazma TNF- α ve IL-8 duzeylerinde iyilesme gorulmustur. Daha buyuk katilimli ve daha uzun sureli sigara birakma sonrasi yapilan calismalarla, sistemik inflamasyondaki duzelmelerin daha ayrintili gosterilebilecegi dusunulmektedir.
在这场灾难中，吸烟、全身炎症、天然粘液客户的退化以及他们与香烟的关系的后果都减少了。Yontem：Saglik Bilimelli大学，Konya Egitim Arastirma Hastanesi Sigara Birakma Poliklinigine basvuran 30 vaka calimaya dahil edilip 27 vaka ile calima tamamlanmistir。肿瘤坏死因子α（TNF-α）、白细胞介素（IL）-4、IL-6、IL-8、IL-10和sakarine night surfaces（STT），记录并吸烟2个月后合并。事件：在这种钙中，STT的香烟在停药2个月后得到了显著保护（p＜0001）。将香烟加入基线水平为2的卡比尔杀菌剂后，血清TNF-α（p=0.035）和IL-8（p=0.002）传感器。我们发现月球明显缩小了。当你有一定程度的carsilastic时，你在2点后就开始吸烟了。当月血清IL-6（p=0.132）和IL-10（p=0.657）水平表明血清IL-6（p=0.0132）的降解没有意义。结果：吸烟2个月后，临床和全身炎症测试的TNF-α和IL-8均能治愈轻度黏角。这些是更多的杀手和更严重的香烟，更系统的炎症反应更特异于戈斯特里贝吉。
{"title":"Sigara bırakma sonrası sistemik inflamatuar ve nazal mukosilier yanıttaki değişiklikler","authors":"Ibrahim Solak, Kamile Marakoğlu, Selma Pekgor, Nisa Çetin Kargın, Y. T. Gederet, Necat Alataş, M. Eryılmaz","doi":"10.22391/fppc.474484","DOIUrl":"https://doi.org/10.22391/fppc.474484","url":null,"abstract":"Giris : Bu calismada, sigara birakma sonrasi, hem sistemik inflamasyonda hem de nasal mukosilier klirensde meydana gelen degisiklikleri ve bunlarin sigara icme ozellikleri ile iliskilerinin degerlendirilmesi amaclanmistir. Yontem : Saglik Bilimleri Universitesi Konya Egitim Arastirma Hastanesi Sigara Birakma Poliklinigine basvuran 30 vaka calismaya dahil edilip 27 vaka ile calisma tamamlanmistir. Tumor nekrozis faktor-alfa (TNF-α), interlokin (IL) -4, IL-6, IL-8, IL-10 ve sakarin gecis suresi (STT), kayit ve sigara birakilmasindan 2 ay sonra olculdu. Bulgular : Bu calismada, STT’nin sigara birakildiktan 2 ay sonra anlamli olarak kisaldigi goruldu (p <0,001). Serum TNF-α (p = 0,035) ve IL-8 (p = 0,002) duzeylerinin, bazal seviyelerle karsilastirildiginda, sigara biraktiktan sonraki 2. ayda anlamli olarak azaldigini bulduk. Bazal seviyelerle karsilastirildiginda, sigara biraktiktan sonraki 2. ayda serum IL-6 (p = 0,132) ve IL-10 (p = 0,657) seviyelerinin degisiminin anlamli olmadigi gozlendi. Sonuc : Sigara birakma isleminden iki ay sonra, nazal mukosiliyer klirens ve sistemik inflamatuar yanitta, ozellikle plazma TNF- α ve IL-8 duzeylerinde iyilesme gorulmustur. Daha buyuk katilimli ve daha uzun sureli sigara birakma sonrasi yapilan calismalarla, sistemik inflamasyondaki duzelmelerin daha ayrintili gosterilebilecegi dusunulmektedir.","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42041401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Solak, Abdullah Arslan, R. Kutlu, B. Kozanhan, S. Neşelioğlu, O. Erel, Ç. Çetinkaya, M. Eryılmaz
Giris : Idyopatik ani sensorinoral isitme kaybi (ISSNHL) en onemli insan duyularindan birinin islev kaybina neden olabilen otolojik acil bir durumdur. Son zamanlarda ISSNHL’ nda hiperbarik oksijen tedavisi (HBOT), farmakoterapi ile birlikte populerlik kazanmaktadir. Bu calismada ISSNHL olan hastalarda farmakoterapi ile HBOT’nin sistemik oksidatif stresin yeni bir gostergesi olan tiyol/disulfit homeostrazisinde (TDH) meydana getirdigi degisikliklerin tespiti amaclandi. Yontem : Bu prospektif calismada ISSNHL olan hastalarda, calisma basinda ve standart tedaviyle birlikte HBOT uygulandiktan sonra albumin, total tiyol, native tiyol, disulfit duzeyleri ile disulfit /native tiyol, disulfit /total tiyol ve native tiyol/total tiyol oranlari yeni bir kolorimetrik yontem kullanilarak analiz edilmistir. Bulgular : Calismaya 14’u (%34,1) kadin 27’si (%65,9) erkek olmak uzere 41 ISSNH’ li hasta katildi. Hastalarin yas ortalamasi 48,02±13,10 idi. Hastalarin 24’u (%58,5) sag kulaktan 17’si (%41,5) sol kulaktan sikayeti vardi. Hastalarin baslangica gore tedavi sonrasinda native tiyol (p<0,001), total tiyol (p<0,001), disulfit (p<0,001) ve albumin (p<0,001) degerlerinde istatistiksel olarak anlamli dusme olmustur. Disulfit /native tiyol (p=0,148), disulfit /total tiyol (p=0,172) ve native tiyol/total tiyol (p=0,169) oranlarinda tedavi sonrasinda oncesine gore istatistiki olarak anlamli fark bulunamamistir. Sonuc : Sonuc olarak bu calismada, ISSNHL hastalarda baslangica gore HBOT ve medikal tedavi verildikten sonra tiyol-disulfit dengesinin oksidasyon yonune dogru kayma egiliminde oldugu ve tedavi sonrasi oksidasyonun yuksek oldugu hastalarda tedaviye cevabin daha iyi oldugu gorulmektedir.
输入：Idyopathy传感器突然丢失（ISSNHL）是由于第十一个人体传感器之一失去隔离而导致的自动紧急情况。近年来，ISSNHL的高压氧治疗（HBOT）与药物治疗一起受到欢迎。在这种钙中，ISSNHL患者被诊断为在具有系统性氧化应激的新型甲状腺/二硫化物同源Strazis（TDH）中使用HBOT进行药物治疗的疾病。补充：在对ISSNHL患者应用含钙碱的HBOT和标准治疗后，使用白蛋白、总型、天然型、二硫酸盐法、二硫酸盐/天然型、双硫酸盐/总甲状腺/总甲状腺水平的新比色积分分析以下内容。凸起：Calismaya 14'u（%34,1）kadin 27'si（%65,9）erkek olmak uzere 41 ISSNH'li hasta katildi。平均48.02±13.10。患者的24（58.5）只右耳是17（41.5）只左耳。治疗后，患者的甲状腺（p＜0.001）、总甲状腺（p＞0.001）、二硫化物（p＜001）和白蛋白（p＜0.01）具有统计学意义。二硫酸盐/天然途径（p=0.148）、二硫酸盐/总途径（p=0.172）和天然途径/总通路（p=0.169）在治疗后似乎没有统计学差异。因此，在这场灾难中，HBOT和药物被注射到氧化离子离子的右侧中风中，治疗后氧合增加的患者对治疗的反应更好。
{"title":"İdiopatik ani işitme kaybı olan hastaların tiyol/disülfit homeostazisi üzerine hiperbarik oksijen tedavisinin etkisi","authors":"I. Solak, Abdullah Arslan, R. Kutlu, B. Kozanhan, S. Neşelioğlu, O. Erel, Ç. Çetinkaya, M. Eryılmaz","doi":"10.22391/fppc.470360","DOIUrl":"https://doi.org/10.22391/fppc.470360","url":null,"abstract":"Giris : Idyopatik ani sensorinoral isitme kaybi (ISSNHL) en onemli insan duyularindan birinin islev kaybina neden olabilen otolojik acil bir durumdur. Son zamanlarda ISSNHL’ nda hiperbarik oksijen tedavisi (HBOT), farmakoterapi ile birlikte populerlik kazanmaktadir. Bu calismada ISSNHL olan hastalarda farmakoterapi ile HBOT’nin sistemik oksidatif stresin yeni bir gostergesi olan tiyol/disulfit homeostrazisinde (TDH) meydana getirdigi degisikliklerin tespiti amaclandi. Yontem : Bu prospektif calismada ISSNHL olan hastalarda, calisma basinda ve standart tedaviyle birlikte HBOT uygulandiktan sonra albumin, total tiyol, native tiyol, disulfit duzeyleri ile disulfit /native tiyol, disulfit /total tiyol ve native tiyol/total tiyol oranlari yeni bir kolorimetrik yontem kullanilarak analiz edilmistir. Bulgular : Calismaya 14’u (%34,1) kadin 27’si (%65,9) erkek olmak uzere 41 ISSNH’ li hasta katildi. Hastalarin yas ortalamasi 48,02±13,10 idi. Hastalarin 24’u (%58,5) sag kulaktan 17’si (%41,5) sol kulaktan sikayeti vardi. Hastalarin baslangica gore tedavi sonrasinda native tiyol (p<0,001), total tiyol (p<0,001), disulfit (p<0,001) ve albumin (p<0,001) degerlerinde istatistiksel olarak anlamli dusme olmustur. Disulfit /native tiyol (p=0,148), disulfit /total tiyol (p=0,172) ve native tiyol/total tiyol (p=0,169) oranlarinda tedavi sonrasinda oncesine gore istatistiki olarak anlamli fark bulunamamistir. Sonuc : Sonuc olarak bu calismada, ISSNHL hastalarda baslangica gore HBOT ve medikal tedavi verildikten sonra tiyol-disulfit dengesinin oksidasyon yonune dogru kayma egiliminde oldugu ve tedavi sonrasi oksidasyonun yuksek oldugu hastalarda tedaviye cevabin daha iyi oldugu gorulmektedir.","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68403570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdullah Yazar, Alaaddin Yorulmaz, Esra Türe, Fatih Akın, Ahmet Sert
{"title":"Down Sendromlu hastalarda subklinik hipotiroidizm ve hematolojik parametreler arasındaki ilişki","authors":"Abdullah Yazar, Alaaddin Yorulmaz, Esra Türe, Fatih Akın, Ahmet Sert","doi":"10.22391/fppc.422181","DOIUrl":"https://doi.org/10.22391/fppc.422181","url":null,"abstract":"","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68403516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giris : Fetuste gelisebilecek toksik ve teratolojik yan etkilerinden dolayi, gebelikte gorulen depresyonun tedavisinde kullanilabilecek ilac sayisi oldukca sinirlidir. Calismamizda, gebelik sirasinda depresyon tedavisi icin halk arasinda sik kullanilan kantaron otunun fetus karacigeri uzerine yan etkilerini arastirdik. Yontem: Calismada kullanilan 13 adet disi Wistar albino sican, 8 adet deney grubu, 5 adet de kontrol grubu olmak uzere ayrildi. Gebe kalmalari saglanan deney grubundaki hayvanlara, gebeligin ilk gununden itibaren, gebelik suresince 100 mg/kg/gun kantaron otu ekstresi orogastrik sonda yardimiyla verildi. Kontrol grubundaki sicanlara ise gebeligin ilk gununden itibaren her gun 2 ml distile su orogastrik sonda yardimiyla verildi. Dogan yavrularin karaciger dokulari cikarildi, %10 notral formalin ile fiksasyonu yapildi, alkol takibinden sonra parafin bloklari hazirlandi, alinan kesitler hematoksilen ve eosin ile boyanarak incelendi. Bulgular: Deney grubuna ait karaciger dokularinin histopatolojik degerlendirmesinde mikrovezikuler yaglanma ve hidropik dejenerasyon gozlendi. Sonuc : Kantaron otunun gebe kadinlar veya fetus acisindan guvenilir oldugunu iddia etmek icin yeterli bilgi bulunmadigi sonucuna varildi. Bu otun gebelik kullanimiyla ilgili sakincalarin hekimler tarafindan degerlendirilmesi ve ozellikle birinci basamakta hekimlerin, gebe takiplerinde hastalari bu konuda bilinclendirmesi onem arz etmektedir. Kantaron otunun gebelikte kullanimi ve gerek anne gerek fetuste tum vucuttaki etkilerinin ortaya konmasi icin daha ileri calismalar yapilmasi gerekmektedir.
{"title":"Gebe sıçanlarda kantaron otunun fetüse etkisi","authors":"B. Buyuk, Mehmet Yüncü, Ayhan Eralp, S. Demir","doi":"10.22391/fppc.406844","DOIUrl":"https://doi.org/10.22391/fppc.406844","url":null,"abstract":"Giris : Fetuste gelisebilecek toksik ve teratolojik yan etkilerinden dolayi, gebelikte gorulen depresyonun tedavisinde kullanilabilecek ilac sayisi oldukca sinirlidir. Calismamizda, gebelik sirasinda depresyon tedavisi icin halk arasinda sik kullanilan kantaron otunun fetus karacigeri uzerine yan etkilerini arastirdik. Yontem: Calismada kullanilan 13 adet disi Wistar albino sican, 8 adet deney grubu, 5 adet de kontrol grubu olmak uzere ayrildi. Gebe kalmalari saglanan deney grubundaki hayvanlara, gebeligin ilk gununden itibaren, gebelik suresince 100 mg/kg/gun kantaron otu ekstresi orogastrik sonda yardimiyla verildi. Kontrol grubundaki sicanlara ise gebeligin ilk gununden itibaren her gun 2 ml distile su orogastrik sonda yardimiyla verildi. Dogan yavrularin karaciger dokulari cikarildi, %10 notral formalin ile fiksasyonu yapildi, alkol takibinden sonra parafin bloklari hazirlandi, alinan kesitler hematoksilen ve eosin ile boyanarak incelendi. Bulgular: Deney grubuna ait karaciger dokularinin histopatolojik degerlendirmesinde mikrovezikuler yaglanma ve hidropik dejenerasyon gozlendi. Sonuc : Kantaron otunun gebe kadinlar veya fetus acisindan guvenilir oldugunu iddia etmek icin yeterli bilgi bulunmadigi sonucuna varildi. Bu otun gebelik kullanimiyla ilgili sakincalarin hekimler tarafindan degerlendirilmesi ve ozellikle birinci basamakta hekimlerin, gebe takiplerinde hastalari bu konuda bilinclendirmesi onem arz etmektedir. Kantaron otunun gebelikte kullanimi ve gerek anne gerek fetuste tum vucuttaki etkilerinin ortaya konmasi icin daha ileri calismalar yapilmasi gerekmektedir.","PeriodicalId":31541,"journal":{"name":"Family Practice and Palliative Care","volume":"123 30","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41250609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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