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Associação entre depressão materna e diferenças de gênero no comportamento de crianças: uma revisão sistemática 母亲抑郁与儿童行为性别差异的关系:一项系统综述
Pub Date : 2010-10-15 DOI: 10.1590/S0101-81082010005000001
Lívia Loosli, S. R. Loureiro
Maternal depression has been identified as an adverse condition for child development, and has been associated with behavioral problems, with different manifestations for boys and girls. The objective of the present study was to identify and analyze articles published in indexed journals that address the association between maternal depression and gender differences in relation to child behavior. The review was conducted on the electronic databases MEDLINE, PubMed, PsycINFO, Web of Science, LILACS, SciELO, and Index Psi, using the keywords maternal depression and gender and maternal depression and child sex, and was restricted to articles published in the last 5 years (2004 to 2009). Twenty one empirical articles were identified and systematically analyzed. There was a predominance of prospective longitudinal studies, employing non-clinical samples, without a confirmed diagnosis of maternal depression, which was analyzed in combination with others context variables. Data collection procedures were performed using a variety of measures and informants. Longitudinal and cross-sectional studies confirmed the negative impact of maternal depression on child variables, pointing to the presence of differences between genders, as follows: during school-age years, externalizing and conduct problems for boys and internalizing and depressive problems for girls; during preschool age, predominance of externalizing problems for boys; during adolescence, internalizing problems for girls. These results suggest the need for different intervention strategies aimed at boys and girls who have been exposed to maternal depression, focusing on developmental tasks and with special attention to both genders during school age and to girls during adolescence.
母亲抑郁症已被确定为儿童发育的不利条件,并与行为问题有关,男孩和女孩的表现不同。本研究的目的是识别和分析发表在索引期刊上的文章,这些文章讨论了母亲抑郁与儿童行为方面的性别差异之间的联系。本综述在MEDLINE、PubMed、PsycINFO、Web of Science、LILACS、SciELO和Index Psi电子数据库中进行,检索关键词为母亲抑郁与性别、母亲抑郁与儿童性别,限于最近5年(2004 - 2009)发表的文章。对21篇实证文章进行了识别和系统分析。前瞻性纵向研究占主导地位,采用非临床样本,没有确诊的母亲抑郁症,并结合其他背景变量进行分析。数据收集程序使用各种测量方法和举报人进行。纵向和横断面研究证实了母亲抑郁对儿童变量的负面影响,指出性别之间存在差异,如下:在学龄期间,男孩的外化和行为问题,女孩的内化和抑郁问题;学龄前阶段,外化问题在男孩中占主导地位;在青春期,女孩的内化问题。这些结果表明,需要针对暴露于母亲抑郁症的男孩和女孩采取不同的干预策略,重点关注发展任务,并特别关注学龄期的两性和青春期的女孩。
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引用次数: 4
The Checklist Manifesto: how to get things right, de Atul Gawande 清单宣言:如何把事情做好,de Atul Gawande
Pub Date : 2010-01-01 DOI: 10.1590/S0101-81082010000300009
P. V. Magalhães
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引用次数: 1
Famílias e casais: do sintoma ao sistema 家庭和夫妻:从症状到系统
Pub Date : 2010-01-01 DOI: 10.1590/S0101-81082010000200008
Marcos Hirata Soares
O livro e baseado na terapia familiar estrutural, um seg-mento da teoria sistemica. O modelo estrutural importa os principais conceitos da teoria sistemica, mas foca na forma como a familia delimita as fronteiras entres seus membros (questao dos papeis desempenhados e os limites de cada um). Atraves de uma explicacao de tecnicas experimentadas e desenvolvidas pelos autores durante cerca de 5 decadas e de diversos estudos de casos clinicos, o livro se propoe a de-monstrar um modelo de quatro etapas para acessar e avaliar a familia, direcionando o processo terapeutico com ela.Embora o sofrimento e os diversos desajustes familiares tenham formas diferentes de entendimento segundo os lacos culturais de cada familia, os autores sugerem que a explicacao mais aceitavel para que suas teorias e tecnicas sejam validadas transculturalmente e que todas as pessoas estao sujeitas a for-mas comuns de ver e entender as relacoes familiares. Assim, os autores, enquanto terapeutas, oferecem as familias um tipo de estrutura familiar organizadora, capaz de explicar seus dile-mas, pois melhora a comunicacao e a compreensao mutua em familia, fazendo com que elas, ainda, utilizem esse modelo no seu dia a dia, trazendo inovacoes e ajustando-o as suas manei-ras individuais de ser.Este modelo acima e composto de quatro etapas e tem como meta descobrir o que impede a familia de atingir seus objetivos e, entao, unir-se a ela para conceber uma visao de como passar da fase atual para onde ela deseja estar. Essa complexa tarefa divide-se em quatro etapas, aqui descritas sucintamente:1)
这本书以结构家庭治疗为基础,是系统理论的一部分。结构模型引入了系统理论的主要概念,但侧重于家庭如何界定其成员之间的界限(角色问题和每个成员的界限)。通过对作者在大约50年的经验和发展的技术的解释和几个临床案例研究,这本书提出了一个四步模型来访问和评估家庭,指导治疗过程。尽管家人的痛苦和各种不适应的不同角度的理解每一个家庭的文化关系,作者认为最可接受的解释理论和方法验证transculturalmente所有的人的共同主题是我看到和理解的关系。因此,作者,当家庭治疗师提供一种家庭结构组织,不能够解释他的惩罚,因为有助于提高搜索和在家人,让她们相互理解,还使用在你的日常生活,带来创新模式和调整个人manei边界。上面的模型由四个步骤组成,旨在找出是什么阻碍了家庭实现他们的目标,然后与他们一起设计一个愿景,如何从当前阶段到他们想要达到的目标。这个复杂的任务分为四个步骤,这里简要描述一下:1)
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引用次数: 19
Repercussões do novo Código de Ética Médica na prática psiquiátrica 新医学道德规范对精神病学实践的影响
Pub Date : 2010-01-01 DOI: 10.1590/S0101-81082010000300001
L. Hetem, Rogério Wolf de Aguiar
A sexta edicao do Codigo de Etica Medica esta em vigor desde 13 de abril de 2010. O documento anterior, de 1988, foi revisto pela necessidade de atualizacao sobre os deveres profi ssionais levando-se em conta as mudancas sociais e os progressos tecnologicos ocorridos nas duas ultimas decadas. O resultado do trabalho serio e exaustivo desenvolvido ao longo de 2 anos e muito bom, e os objetivos do projeto foram atingidos. O novo Codigo de Etica Medica representa um avanco para a sociedade e para os medicos na construcao de uma relacao responsavel e etica.O documento e composto de 25 principios fundamen-tais, 10 normas diceologicas (sobre os direitos dos medicos), 118 artigos deontologicos (relacionados aos seus deveres) e quatro disposicoes gerais. As principais novidades sao: o reforco a autonomia do pa-ciente, sem, no entanto, descuidar da do medico; a enfase na importância crescente dos cuidados paliativos para pacientes em estado terminal ou que apresentem doencas cronicas ou incura-veis; e a ampliacao do alcance das normativas, agora abarcando o medico em cargo de gestao, pesquisa e ensino. Ha tambem maior detalhamento das diretrizes relacionadas a publicidade medica, ao confl ito de interesses, a solicitacao de segunda opiniao, a res-ponsabilidade medica, ao uso de placebo em pesquisa e ao envol-vimento com planos de fi nanciamento, cartoes de desconto ou consorcios para procedimentos medicos. Finalmente, como seria de se esperar num documento dessa importância, estimula-se a cautela na incorporacao de novas tecnicas em saude.O novo Codigo reitera a vedacao da eutanasia, de acordo com a lei brasileira, mas protege a ortotanasia, desestimulan-do a distanasia. A ortotanasia se refere ao respeito a evolucao natural das doencas graves e terminais, desencorajando o uso desnecessario de meios artifi ciais de prolongamento da vida que nao tenham sentido curativo ou aliviador do sofrimento (distanasia).Outro campo contemporâneo da pratica medica abor-dado pelo novo Codigo se refere a fertilizacao assistida e tambem a genetica. Novos desafi os eticos provocados pelos grandes progressos da pesquisa nessas areas foram enfrenta-dos com muita seriedade.As repercussoes dessas novidades para a pratica psiquia-trica sao positivas. Sem duvida, contribuirao para sua melho-ria e efetividade na medida em que estimulam uma relacao medico-paciente mais equilibrada e respeitosa, ao mesmo tempo em que a protegem de interferencia externa. A pesquisa em psicofarmacologia clinica, por outro lado, notadamente a que se ocupa da e fi cacia e tolerabilidade de no-vos medicamentos, vai sentir a proibicao de ensaios controla-dos com placebo “quando houver tratamento efi caz e efetivo para a doenca pesquisada”. Isso porque, sabe-se bem, algumas sindromes psiquiatricas, dentre elas as depressoes e alguns transtornos de ansiedade, sao susceptiveis a efeito placebo em porcentagem nao desprezivel. Por isso, a boa intencao de privar alguns pacientes de tratamentos com efi cacia ja comprov
《医学道德规范》第六版自2010年4月13日起生效。1988年之前的文档,但更新的需求在功课fi。考虑到社会的转变和进步tecnologicos发生在最后两年。经过两年多的认真和彻底的工作,结果非常好,项目目标已经实现。新的医学道德准则代表了社会和医生在建立负责任和道德关系方面的进步。该文件由25项基本原则、10项教学规则(关于医生的权利)、118条道德条款(与医生的职责有关)和4项一般规定组成。主要的创新是:加强病人的自主权,但不忽视医生的自主权;强调临终病人或患有慢性或无法治愈疾病的病人的姑息治疗日益重要;以及监管范围的扩大,现在包括了负责管理、研究和教学的医生。医疗有更详细的指导方法相关的广告,ito confl感兴趣的,问solicitacao周一,医疗责任,涉及使用安慰剂的研究和发展计划的fi医疗用信用卡的折扣或财团融资过程。最后,正如人们在如此重要的文件中所期望的那样,鼓励谨慎地纳入新的卫生技术。根据巴西法律,新法典重申了安乐死的禁令,但保护了正安乐死,阻止了距离。ortotanasia指的是尊重自然发展的严重疾病和终端,既不恰当的使用意味着artifi社会生命的延续没有治愈或缓解痛苦(distanasia)。新法典所涵盖的另一个当代医学实践领域涉及辅助受精和遗传学。新挑战fi造成的你的道德水平在这些领域的研究有很大的进展是怎么样面对非常认真。这些创新对心理实践的影响是积极的。毫无疑问,它们将有助于其改善和有效性,因为它们促进了一种更加平衡和尊重的医患关系,同时保护它不受外部干扰。临床精神药理学的研究,另一方面,特别是处理和ficacia和不可磨灭的在你们测试药物,会禁止安慰剂控制-“当有治疗疾病的实际fi卡兹,研究”。这是因为,众所周知,一些精神疾病,包括抑郁症和一些焦虑症,在很大程度上容易受到安慰剂效应的影响。所以就努力留在有些病人的治疗和ficacia已经被证实,即使在条件控制和监测的伦理委员会,可以把一个更大的数量的特异功能-soas的你没有真正有效的药物控制的邪恶,敏感性,把之前的调整的通用电气psicofarmacologica。法典的现代化及其生效也引起了全国媒体的关注。有许多采访和发表的证词,这无疑有助于传播医疗类别的严重性,通过理事会系统,面对医疗实践和向公众提供的服务的道德质量。
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引用次数: 1
Tobacco smoking and depression during pregnancy 怀孕期间吸烟和抑郁
Pub Date : 2010-01-01 DOI: 10.1590/S0101-81082010000200004
K. Jansen, Aline Rezende Curra, L. Souza, R. Pinheiro, Inácia Moraes, Myriam Siqueira da Cunha, R. Silva
OBJETIVOS: Avaliar a associacao entre consumo de cigarros e depressao durante a gravidez e identificar fatores associados. METODO: Trata-se de estudo transversal, que incluiu uma populacao de 1.264 gestantes atendidas nos servicos de maior fluxo do Sistema Unico de Saude (SUS) da cidade de Pelotas (RS), Brasil. A depressao foi avaliada utilizando a Edinburgh Postnatal Depression Scale, e o consumo de tabaco foi verificado atraves de questoes abertas. Na analise estatistica, utilizou-se a regressao de Poisson. RESULTADOS: A prevalencia de depressao durante a gestacao foi de 21,2%; 19,3% das gestantes com depressao eram fumantes. As mulheres que fumaram durante a gravidez apresentaram 1,72 (intervalo de confianca de 95%: 1,27-2,34) maior probabilidade de ter depressao. CONCLUSAO: Os resultados indicam uma relacao positiva entre o consumo de cigarros durante a gravidez e episodios depressivos.
目的:评估吸烟与怀孕期间抑郁之间的关系,并确定相关因素。方法:这是一项横断面研究,包括1264名在巴西佩洛塔斯市统一卫生系统(SUS)最高流量服务的孕妇。抑郁评估采用爱丁堡产后抑郁量表,吸烟使用采用开放式问卷。在统计分析中,采用泊松回归。结果:妊娠期抑郁患病率为21.2%;妊娠期抑郁患病率为21.2%。19.3%患有抑郁症的孕妇吸烟。怀孕期间吸烟的女性患抑郁症的几率更高1.72(95%置信区间:1.27 - 2.34)。结论:结果表明,怀孕期间吸烟与抑郁发作之间存在正相关关系。
{"title":"Tobacco smoking and depression during pregnancy","authors":"K. Jansen, Aline Rezende Curra, L. Souza, R. Pinheiro, Inácia Moraes, Myriam Siqueira da Cunha, R. Silva","doi":"10.1590/S0101-81082010000200004","DOIUrl":"https://doi.org/10.1590/S0101-81082010000200004","url":null,"abstract":"OBJETIVOS: Avaliar a associacao entre consumo de cigarros e depressao durante a gravidez e identificar fatores associados. METODO: Trata-se de estudo transversal, que incluiu uma populacao de 1.264 gestantes atendidas nos servicos de maior fluxo do Sistema Unico de Saude (SUS) da cidade de Pelotas (RS), Brasil. A depressao foi avaliada utilizando a Edinburgh Postnatal Depression Scale, e o consumo de tabaco foi verificado atraves de questoes abertas. Na analise estatistica, utilizou-se a regressao de Poisson. RESULTADOS: A prevalencia de depressao durante a gestacao foi de 21,2%; 19,3% das gestantes com depressao eram fumantes. As mulheres que fumaram durante a gravidez apresentaram 1,72 (intervalo de confianca de 95%: 1,27-2,34) maior probabilidade de ter depressao. CONCLUSAO: Os resultados indicam uma relacao positiva entre o consumo de cigarros durante a gravidez e episodios depressivos.","PeriodicalId":31894,"journal":{"name":"Boletim Geografico do Rio Grande do Sul","volume":"30 1","pages":"44-47"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87006547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Inventário de expectativas de resultados em usuários de maconha (IERUM): construção e validação 大麻使用者预期结果量表(IERUM):构建和验证
Pub Date : 2010-01-01 DOI: 10.1590/S0101-81082010000100005
Rosemeri Siqueira Pedroso, M. D. Castro, Renata Brasil Araújo
Introduction: This study presents the development and validation of the Inventory of Outcome Expectancy in Marijuana Users (Inventario de Expectativas de Resultados em Usuarios de Maconha, IERUM), which evaluates the outcome expectancy regarding marijuana use, and may be useful in the treatment and prognosis of marijuana-dependent individuals. Method: The sample comprised 181 male (n = 145) and female (n = 36) marijuana users. Their age ranged from 18 to 55 years old (28.34±8.57). One hundred and eighteen patients were hospitalized at a chemical dependency unit, 23 were being treated in an outpatient clinic, 25 were receiving treatment in a self-help group (drug addicts anonymous, alcoholic anonymous), and 15 were not being treated. The 17-item scale was developed based on the experience related to chemical dependency and scale validation, with the semantic validation being the first phase of the process. Results: According to the factor analysis, the IERUM was divided into five factors (emotional aspects, perception, craving, cognitive aspects, and sexual aspects) that accounted for 60.18% of the variance. Conclusion: The IERUM showed good psychometric properties and can be used to evaluate the outcome expectancy related to marijuana use.
简介:本研究介绍了大麻使用者结果预期量表(Inventario de Expectativas de Resultados em Usuarios de Maconha, IERUM)的开发和验证,该量表评估了大麻使用的结果预期,可能对大麻依赖个体的治疗和预后有用。方法:样本包括181名男性(145名)和36名女性(36名)大麻使用者。年龄18 ~ 55岁(28.34±8.57)。118名患者在化学药物依赖部门住院,23名患者在门诊接受治疗,25名患者在自助小组接受治疗(吸毒匿名,酗酒匿名),15名患者未接受治疗。17项量表是根据化学依赖和量表验证的相关经验开发的,其中语义验证是该过程的第一阶段。结果:根据因子分析,IERUM分为五个因素(情感方面、感知方面、渴望方面、认知方面和性方面),占方差的60.18%。结论:IERUM具有良好的心理测量特性,可用于评价大麻使用相关的结果期望。
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引用次数: 3
Resenha do livro Psicoterapia interpessoal: guia prático do terapeuta 《人际心理治疗:治疗师的实用指南》一书的评论
Pub Date : 2010-01-01 DOI: 10.1590/S0101-81082010000100006
Marcos Hirata Soares
This book is aimed at those professionals who provide mental health services. According to its preface, it was written based on a method of psychotherapeutic treatment developed over a 30-year period and called interpersonal psychotherapy (IPT). This method was initially aimed at major depression, but later it was adapted to other complex psychiatric disorders such as borderline personality. The objective of this work was to be an easy to read quick reference book, providing descriptions of the methods used to approach and manage clinical cases, based on the assumption that professionals (readers) have knowledge of psychotherapy and skills to manage people diagnosed with mood or anxiety disorders. It is worth emphasizing that although none of the works by Carl Rogers are mentioned in this book, its content is very similar to Rogers’s theory, except for the section regarding mood disorders, which is addressed in a thorough manner, including the approach to be used within each context. Rogers is considered to be the pioneer in the use of interpersonal relationship as a pedagogical and psychotherapeutic resource. The book was very well written, considering both the didactic and scientifi c point of view, that is, it is easy to read and understand, mentioning articles published in very important journals for the scientifi c and academic community.
这本书的目标读者是那些提供心理健康服务的专业人士。根据前言,这本书是根据30多年来发展起来的人际心理治疗(IPT)的心理治疗方法编写的。这种方法最初是针对重度抑郁症的,但后来被应用于其他复杂的精神疾病,如边缘型人格。这本书的目的是成为一本易于阅读的快速参考书,提供了用于处理和管理临床病例的方法的描述,基于专业人士(读者)具有心理治疗知识和管理被诊断为情绪或焦虑障碍的人的技能的假设。值得强调的是,虽然本书中没有提到卡尔·罗杰斯的任何作品,但除了关于情绪障碍的部分外,其内容与罗杰斯的理论非常相似,该部分以一种彻底的方式进行了讨论,包括在每种情况下使用的方法。罗杰斯被认为是使用人际关系作为教学和心理治疗资源的先驱。这本书写得非常好,考虑到教学和科学的观点,也就是说,它很容易阅读和理解,提到了在科学和学术界非常重要的期刊上发表的文章。
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引用次数: 0
Versão brasileira da Impact of Event Scale (IES): tradução e adaptação transcultural 事件影响量表(IES)的巴西版本:翻译和跨文化适应
Pub Date : 2010-01-01 DOI: 10.1590/S0101-81082010000300005
A. C. Silva, A. Nardi, Mardi J. Horowitz
INTRODUCTION: The aim of the Impact of Event Scale (IES) is to evaluate subjective distress associated with life events. The instrument is not focused on a specific situation, but rather on the particular characteristics of such events. OBJECTIVE: To describe the translation and semantic adaptation of the IES into Brazilian Portuguese. METHODS: The process consisted of translations and back-translations performed by four independent examiners without prior knowledge of the original scale. The synthetic version was developed by a mental health specialist with proficiency in both languages. Subsequently, the adapted scale was applied in an experimental group for evaluation. The new/adapted version was revised and approved by the author of the original instrument. RESULTS: We describe all study phases, including translations, back-translations, and the development of the synthetic version, for each of the 15 items contained in the original instrument. The mental health specialist assisted in adapting the terms employed taking into consideration the construct under investigation in each case. The experimental application allowed to identify potential difficulties in the understanding of specific items and to subsequently adjust these items. Fifteen items were developed in Brazilian Portuguese for this version of the scale. CONCLUSIONS: The methodology employed in the present study allowed us to conduct the cross-cultural adaptation of the IES scale into Brazilian Portuguese.
简介:事件影响量表(IES)的目的是评估与生活事件相关的主观痛苦。该文书的重点不是某一具体情况,而是这类事件的具体特点。目的:描述IES在巴西葡萄牙语中的翻译和语义改编。方法:该过程包括翻译和反翻译,由四名独立的审查员在不事先了解原始量表的情况下进行。合成版本是由精通两种语言的心理健康专家开发的。随后,将改编后的量表应用于实验组进行评价。新/改编版本由原始文书的作者修改并批准。结果:我们描述了原始仪器中包含的15个项目的所有研究阶段,包括翻译、反翻译和合成版本的开发。心理健康专家协助调整了所使用的术语,同时考虑到每个案例中正在调查的结构。实验应用允许识别理解特定项目的潜在困难,并随后调整这些项目。这个版本的量表用巴西葡萄牙语开发了15个项目。结论:本研究采用的方法允许我们对IES量表进行巴西葡萄牙语的跨文化适应。
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引用次数: 12
Fatores associados ao uso de psicofármacos em idosos asilados 老年庇护者使用精神药物的相关因素
Pub Date : 2010-01-01 DOI: 10.1590/S0101-81082010000200003
Giancarlo Lucchetti, Alessandra Lamas Granero, S. Pires, Milton Luiz Gorzoni, Sérgio Tamai
INTRODUCTION: Nursing homes providing elderly care present a high prevalence of interns using psychoactive drugs for the control of behavioral disorders. Few Brazilian studies have so far focused on this aspect of elderly care. OBJECTIVE: To evaluate the factors associated with use of psychoactive drugs in institutionalized elderly patients. METHODS: A cross-sectional, retrospective study was carried out based on medical charts of all elderly patients (60 years and over) treated in a nursing home, independently of their diseases. Logistic regression analysis was performed to assess factors associated with the use of psychoactive drugs in the institution. RESULTS: Two hundred and nine patients were evaluated (73.2% females), suffering predominantly of dementia syndromes, sequelae of stroke or cranial trauma, and hypertension. Of these, 123 patients (58.9%) were using some type of psychoactive drug, mainly antipsychotics and antidepressants. Logistic regression analysis revealed an association between antipsychotic drug use and dementia (p = 0.000), whereas antidepressant drug use was associated with a higher number of drugs (p = 0.004) and depression (p = 0.000). In general, the use of psychoactive drugs was strongly associated with depression (p = 0.000), dementia (p = 0.006), and psychiatric disorders (p = 0.02). There were no associations with sex, functional status or age. CONCLUSION: There is a high consumption of psychoactive drugs in nursing homes. The association between polypharmacy and depression is evident, and patients with dementia were shown to receive more antipsychotics than other patients. Factors such as age or sex, usually relevant among outpatients, did not present association with psychoactive drug use in nursing home patients.
简介:养老院提供老年护理的实习生使用精神活性药物来控制行为障碍的患病率很高。迄今为止,很少有巴西的研究关注老年人护理的这一方面。目的:探讨住院老年患者精神药物使用的相关因素。方法:对所有在养老院接受治疗的老年患者(60岁及以上)的病历进行横断面、回顾性研究,不考虑其疾病。采用Logistic回归分析来评估与该院精神药物使用相关的因素。结果:209例患者(73.2%为女性),主要患有痴呆综合征、脑卒中或颅脑外伤后遗症和高血压。其中,123例(58.9%)患者使用某种精神活性药物,主要是抗精神病药和抗抑郁药。逻辑回归分析显示抗精神病药物的使用与痴呆之间存在关联(p = 0.000),而抗抑郁药物的使用与较高的药物数量(p = 0.004)和抑郁症(p = 0.000)相关。总的来说,精神活性药物的使用与抑郁症(p = 0.000)、痴呆(p = 0.006)和精神障碍(p = 0.02)密切相关。这与性别、功能状态或年龄无关。结论:养老院精神活性药物的消耗量较大。多种药物治疗与抑郁症之间的联系是显而易见的,痴呆症患者比其他患者接受更多的抗精神病药物治疗。通常与门诊患者相关的年龄或性别等因素与养老院患者的精神活性药物使用没有关联。
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引用次数: 16
Association between cognitive impairment and presence of the apolipoprotein E epsilon4 allele in elderly patients with major depressive disorder 老年抑郁症患者认知障碍与载脂蛋白E ε 4等位基因存在的关系
Pub Date : 2010-01-01 DOI: 10.1590/S0101-81082010000200007
D. Bezerra, Q. Cordeiro, E. Nakano, H. Vallada, C. Bottino
This knowledge has generated interest in the in fl uence of ApoE variants on cognition in different psychiatric conditions. Thus, we have performed a study in order to investigate the role of the ApoE4 allele in the cognition of patients with major depressive disorder according to the criteria established by the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV).Thirteen elderly patients older than 60 years [nine women (69.2%) and four men (30.8%)], all of them with a diagnosis of major depressive disorder according to DSM-IV criteria, were included in the study. Blood samples of all subjects were collected for genetic investigation. Patients were divided into two groups, according to the presence or absence of the ApoE4 allele (ApoE4 and non-ApoE4 groups). Genotyping was performed by two investigators according to Hixson & Vernier,
这一知识引起了人们对ApoE变体在不同精神疾病中对认知的影响的兴趣。因此,我们根据《精神疾病诊断与统计手册》第4版(DSM-IV)的标准,开展了一项研究,以探讨ApoE4等位基因在重度抑郁症患者认知中的作用。本研究纳入13例60岁以上的老年患者[女性9例(69.2%),男性4例(30.8%)],均根据DSM-IV标准诊断为重度抑郁症。采集所有受试者的血液样本进行基因调查。根据ApoE4等位基因的存在与否将患者分为两组(ApoE4组和非ApoE4组)。根据Hixson & Vernier的说法,基因分型是由两名研究人员进行的,
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引用次数: 0
期刊
Boletim Geografico do Rio Grande do Sul
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