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Em busca das origens desenvolvimentais dos transtornos mentais 寻找精神障碍的发展起源
Pub Date : 2009-01-01 DOI: 10.1590/S0101-81082009000100005
G. Polanczyk
INTRODUCTION: Developmental psychopathology is a discipline that integrates epidemiological, social, genetic, developmental, and psychopathological perspectives to understand the origins and courses of mental disorders. In the present paper, theoretical concepts and approaches applied with the purpose of understanding the developmental origins of mental disorders are discussed. RESULTS: According to developmental psychopathology, mental disorders are possible outcomes of the developmental process that depend upon social, genetic, and environmental influences. These factors are linked in different ways and levels, exerting a dimensional effect. The following factors are addressed: a) approaches to determine a causal effect between environmental factors and mental disorders; b) the importance of understanding biological mechanisms by which environmental and genetic factors exert their effect; c) genetic factors predicting the exposure to environmental stressors; d) genetic factors moderating the effect of environmental stressors. CONCLUSIONS: The origins of mental disorders can be clarified by data from studies that use complementary approaches and concepts, integrating social, genetic, environmental and developmental influences.
发展精神病理学是一门整合流行病学、社会、遗传、发展和精神病理学观点的学科,旨在了解精神障碍的起源和过程。在本文中,理论概念和方法的应用,以了解精神障碍的发展起源的目的进行了讨论。结果:根据发展精神病理学,精神障碍是依赖于社会、遗传和环境影响的发展过程的可能结果。这些因素以不同的方式和层次联系在一起,产生了维度效应。涉及以下因素:a)确定环境因素与精神障碍之间因果关系的方法;B)了解环境和遗传因素发挥作用的生物学机制的重要性;C)预测环境应激因素暴露的遗传因素;D)遗传因素缓和环境压力因素的影响。结论:精神障碍的起源可以通过使用互补方法和概念的研究数据来澄清,这些研究综合了社会、遗传、环境和发育影响。
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引用次数: 7
Cognição social na esquizofrenia: um enfoque em habilidades teoria da mente 精神分裂症的社会认知:能力心智理论的焦点
Pub Date : 2009-01-01 DOI: 10.1590/S0101-81082009000400005
H. Tonelli, C. Alvarez
"Teoria da mente" e o nome que tem sido dado a habilidade que os seres humanos tem de inferir os estados mentais ou as intencoes de outros seres humanos. Tais habilidades fazem parte de um grupo maior de capacidades cognitivas, especificamente relacionadas ao comportamento social, denominado cognicao social. A esquizofrenia e um transtorno mental que costuma cursar grave comprometimento do funcionamento social. Existem varios estudos correlacionando transtornos das habilidades teoria da mente e sintomas da esquizofrenia com resultados ainda controversos. Muitos autores acreditam que os sintomas da esquizofrenia podem ser diretamente compreendidos a luz de alteracoes das habilidades teoria da mente, enquanto outros argumentam que as alteracoes dessas habilidades observadas em esquizofrenicos sao reflexo de seu comprometimento cognitivo geral. Ainda existem poucos estudos relacionando o impacto do uso de antipsicoticos sobre a cognicao social e habilidades teoria da mente e eles apresentam problemas metodologicos.
“心理理论”是指人类推断他人心理状态或意图的能力。这些技能是一个更大的认知能力群体的一部分,专门与社会行为有关,称为社会认知。精神分裂症是一种精神障碍,通常会严重损害社会功能。有几项研究将心理理论技能障碍和精神分裂症症状联系起来,但结果仍有争议。许多作者认为,精神分裂症的症状可以通过心理理论能力的变化直接理解,而其他人则认为,在精神分裂症患者身上观察到的这些能力的变化反映了他们的整体认知障碍。很少有研究将抗精神病药物的使用对社会认知和心理理论技能的影响联系起来,它们存在方法论问题。
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引用次数: 3
Tradução para o português da escala M-CHAT para rastreamento precoce de autismo 用于自闭症早期筛查的移动聊天量表的葡萄牙语翻译
Pub Date : 2008-12-01 DOI: 10.1590/S0101-81082008000400011
Mirella Fiuza Losapio, Milena Pereira Pondé
INTRODUCTION: The Modified Checklist for Autism in Toddlers (M-CHAT) is a screening instrument for autism that can be applied to parents of children aged 18-24 months. It is self-applicable, simple, and has high sensibility and specificity. It was developed in English and it is still not available in Portuguese. In the scientific literature there is no agreement as to the translation technique, cross-cultural adaptation being one of the possibilities. The objective of the present study was to translate the M-CHAT scale from English into Brazilian Portuguese to scan early autism, preserving cross-cultural equivalence. METHOD: After obtaining permission from the author of the scale, its translation was performed, followed by its back-translation; evaluation of reference equivalence; first pretest in a sample of the target population; evaluation of general equivalence; evaluation by specialists in infantile autism; development of a preliminary version; second pretest with parents of autistic children treated in a Pediatric Ambulatory of the Brazilian Public Health System; and development of its final version. RESULTS: Evaluation of reference equivalence showed that 78% of the questions were similar, 13% approximate, and 9% different. Of the 20 people interviewed in the first pretest, nine understood 100% of the questions. The second pretest demonstrated good acceptance and understanding by the target population, with no complaints in 70% of the sample. After detailed evaluations, the final version was developed. CONCLUSION: The study makes the Portuguese version of the M-CHAT scale available, which was considered adequate by specialists and understood by the population.
简介:修改后的幼儿自闭症检查表(M-CHAT)是一种自闭症筛查工具,适用于18-24个月儿童的父母。该方法具有自适用、简便、敏感性和特异性高的特点。它是用英语开发的,现在还没有葡萄牙语版本。在科学文献中,关于翻译技巧没有达成一致意见,跨文化改编是一种可能性。本研究的目的是将M-CHAT量表从英语翻译成巴西葡萄牙语,以扫描早期自闭症,保持跨文化对等。方法:在获得量表作者许可后,对量表进行翻译,再进行反翻译;参考文献等效性评价;首先在目标人群的样本中进行预测;一般等效性的评价;儿童自闭症专家评估;初步版本的开发;对在巴西公共卫生系统儿科门诊接受治疗的自闭症儿童的父母进行第二次预测;以及最终版本的开发。结果:文献等价性评价结果显示,78%的问题相似,13%近似,9%不同。在第一次预测中接受采访的20人中,有9人100%理解了问题。第二次预试显示了目标人群的良好接受和理解,70%的样本中没有抱怨。经过详细的评估,最终版本被开发出来。结论:该研究提供了葡萄牙语版的M-CHAT量表,专家认为该量表是足够的,并且为人群所理解。
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引用次数: 74
APRS 70 anos: participe desta história 70年后:参与这个故事
Pub Date : 2008-12-01 DOI: 10.1590/S0101-81082008000400001
Fernando Lejderman
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引用次数: 0
Perfil dos usuários do serviço de teleatendimento sobre drogas de abuso VIVAVOZ 药物滥用电话服务VIVAVOZ用户简介
Pub Date : 2008-12-01 DOI: 10.1590/S0101-81082008000400007
M. F. Souza, E. Kohlrausch, Cláudia Galvão Mazoni, Taís de Campos Moreira, Simone Fernandes, Denise Conceição Mesquita Dantas, Maristela Ferigolo, H. M. T. Barros
INTRODUCTION: Drug abuse is a major public health problem. Telephone interventions have been used as a treatment method. This study aimed at describing the sociodemographic profile, consumption pattern and dependence on psychoactive substances of individuals seeking help in a telephone service on drugs of abuse. METHODS: Data were collected by previously trained consultants using an electronic protocol throughout the first year of the service. Instruments were applied to find the sociodemographic profile, consumption pattern and dependence of drug users. Descriptive statistics was used to estimate distribution of variables, and the data are presented as frequencies. RESULTS: Throughout the study period there were 28,257 calls, of which 7,956 were included. In total there was higher prevalence of women, students, single individuals, older than 35 years, with incomplete primary education and family income lower than five minimum wages. Men aged 18-25 years were prevalent in the sample. The most frequently used drugs were tobacco, cannabis, alcohol and cocaine. Tobacco use was similar for both genders. Males used more illicit drugs. Most drug users were dependent, and men had higher rates of addiction to tobacco and solvents. CONCLUSIONS: These results outline the profile of individuals who seek care through a telephone service, showing the importance of these services for the population and guiding preventive actions.
药物滥用是一个重大的公共卫生问题。电话干预已被用作一种治疗方法。这项研究的目的是描述在药物滥用电话服务中寻求帮助的个人的社会人口学概况、消费模式和对精神活性物质的依赖。方法:数据是由以前受过培训的顾问在服务的第一年使用电子协议收集的。使用各种工具了解吸毒者的社会人口特征、消费模式和依赖性。使用描述性统计来估计变量的分布,数据以频率表示。结果:在整个研究期间,有28,257个电话,其中7,956个被纳入。总的来说,妇女、学生、单身人士、35岁以上、未完成初等教育和家庭收入低于五种最低工资的比例较高。18-25岁的男性在样本中普遍存在。最常使用的毒品是烟草、大麻、酒精和可卡因。男女的烟草使用情况相似。男性更多地使用非法药物。大多数吸毒者是依赖的,男性对烟草和溶剂上瘾的比例更高。结论:这些结果概述了通过电话服务寻求护理的个人概况,显示了这些服务对人口和指导预防行动的重要性。
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引用次数: 9
Rimonabant: perspectives and controversies 利莫那班:观点和争议
Pub Date : 2008-12-01 DOI: 10.1590/S0101-81082008000400014
Karine Zortéa, Rafaela Festugatto Tartari
Caros Editores, Doenças cardiovasculares são consideradas um problema de saúde pública, sendo responsáveis por 30% das mortes no mundo1. Diabetes, hipertensão arterial, tabagismo e o surgimento de novos fatores de risco (aumento da circunferência abdominal e dislipidemia), contribuem reconhecidamente para o risco cardiovascular global2. A população adulta americana apresenta cerca de 66% de sobrepeso e 34% de obesidade3. No Brasil, a prevalência é de aproximadamente 32% de sobrepeso e 8% de obesidade4. Conseqüentemente, especialistas têm desenvolvido novas condutas para tratar/prevenir essa condição. Vem crescendo a atenção no potencial terapêutico das substâncias que interferem no sistema endocanabinóide5, devido ao seu papel no controle da ingestão alimentar e balanço energético. Este sistema age em áreas específicas do cérebro, como o hipotálamo, e em tecidos periféricos (adipócitos, hepatócitos, trato gastrointestinal e músculo esquelético). Portanto, drogas (rimonabanto) que interferem em sua ação são promissoras no tratamento de diversas doenças, incluindo a obesidade, dislipidemia, resistência à insulina e aterosclerose6. O rimonabanto tem aprovação no Brasil7 e na Europa, mas não nos Estados Unidos8. Grandes estudos comprovaram a eficácia do rimonabanto, como o RIO-Europe, RIO-North America, RIO-Lipids e RIO-Diabetes. Um ano de tratamento com rimonabanto 20 mg/dia, juntamente com uma dieta hipocalórica e promoção de atividade física, produziram redução no peso, na circunferência da cintura, e melhoras no colesterol HDL, triglicerídeos, glicose e resistência à insulina. Apesar de o rimonabanto ser bem tolerado, pode apresentar efeitos colaterais como alterações no humor, depressão, ansiedade, tonturas, náuseas e, até mesmo, ideações suicidas9. Carta aos editores
亲爱的编辑们,心血管疾病被认为是一个公共健康问题,占全球死亡人数的30%。糖尿病、高血压、吸烟和新的危险因素(腰围增加和血脂异常)的出现,都是心血管风险的重要因素2。美国成年人中约66%超重,34%肥胖。在巴西,超重的患病率约为32%,肥胖的患病率为8%。因此,专家们开发了新的方法来治疗/预防这种情况。由于干扰内源性大麻素系统的物质在控制食物摄入和能量平衡方面的作用,人们越来越关注其治疗潜力。该系统作用于大脑的特定区域,如下丘脑和周围组织(脂肪细胞、肝细胞、胃肠道和骨骼肌)。因此,干扰利莫那班托作用的药物(利莫那班托)有望治疗多种疾病,包括肥胖、血脂异常、胰岛素抵抗和动脉粥样硬化6。利莫那班托在巴西和欧洲得到了批准,但在美国没有。主要的研究已经证明了利莫那班托的有效性,如RIO-Europe, RIO-North America, RIO-Lipids和RIO-Diabetes。每天20毫克的利莫那班治疗一年,加上低热量饮食和促进体育活动,体重、腰围减少,高密度脂蛋白胆固醇、甘油三酯、葡萄糖和胰岛素抵抗改善。虽然利莫那班耐受性良好,但它可能会出现情绪变化、抑郁、焦虑、头晕、恶心,甚至自杀念头等副作用。给编辑的信
{"title":"Rimonabant: perspectives and controversies","authors":"Karine Zortéa, Rafaela Festugatto Tartari","doi":"10.1590/S0101-81082008000400014","DOIUrl":"https://doi.org/10.1590/S0101-81082008000400014","url":null,"abstract":"Caros Editores, Doenças cardiovasculares são consideradas um problema de saúde pública, sendo responsáveis por 30% das mortes no mundo1. Diabetes, hipertensão arterial, tabagismo e o surgimento de novos fatores de risco (aumento da circunferência abdominal e dislipidemia), contribuem reconhecidamente para o risco cardiovascular global2. A população adulta americana apresenta cerca de 66% de sobrepeso e 34% de obesidade3. No Brasil, a prevalência é de aproximadamente 32% de sobrepeso e 8% de obesidade4. Conseqüentemente, especialistas têm desenvolvido novas condutas para tratar/prevenir essa condição. Vem crescendo a atenção no potencial terapêutico das substâncias que interferem no sistema endocanabinóide5, devido ao seu papel no controle da ingestão alimentar e balanço energético. Este sistema age em áreas específicas do cérebro, como o hipotálamo, e em tecidos periféricos (adipócitos, hepatócitos, trato gastrointestinal e músculo esquelético). Portanto, drogas (rimonabanto) que interferem em sua ação são promissoras no tratamento de diversas doenças, incluindo a obesidade, dislipidemia, resistência à insulina e aterosclerose6. O rimonabanto tem aprovação no Brasil7 e na Europa, mas não nos Estados Unidos8. Grandes estudos comprovaram a eficácia do rimonabanto, como o RIO-Europe, RIO-North America, RIO-Lipids e RIO-Diabetes. Um ano de tratamento com rimonabanto 20 mg/dia, juntamente com uma dieta hipocalórica e promoção de atividade física, produziram redução no peso, na circunferência da cintura, e melhoras no colesterol HDL, triglicerídeos, glicose e resistência à insulina. Apesar de o rimonabanto ser bem tolerado, pode apresentar efeitos colaterais como alterações no humor, depressão, ansiedade, tonturas, náuseas e, até mesmo, ideações suicidas9. Carta aos editores","PeriodicalId":31894,"journal":{"name":"Boletim Geografico do Rio Grande do Sul","volume":"26 1","pages":"241-242"},"PeriodicalIF":0.0,"publicationDate":"2008-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87929437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Avaliação da sintomatologia depressiva de mulheres no climatério com a escala de rastreamento populacional para depressão CES-D 使用人群抑郁筛查量表CES-D评价更年期妇女的抑郁症状
Pub Date : 2008-12-01 DOI: 10.1590/S0101-81082008000400008
Rita de Cássia Pereira Fernandes, M. Rozenthal
INTRODUCTION: The objective of this study was to evaluate depressive symptoms in climacteric women using the Center for Epidemiological Studies Depression Scale (CES-D) from the National Institute of Mental Health (USA). METHOD: This is a cross-sectional study carried out in a gynecological outpatient unit in Rio de Janeiro, Brazil, including 151 climacteric women between 40 and 65 years of age. The CES-D was used to assess depressive symptoms and a structured interview obtained sociodemographic, clinical and gynecological data. A score above 15 points on the CES-D was considered as a cut-point for depressive state. RESULTS: Mean CES-D score was 9.2 points (standard deviation = 9.0). Insomnia, sadness and despondency had the highest scores. There was no significant association between CES-D scores and the climacteric period, sociodemographic, clinical or gynecological characteristics, except for women with psychiatric symptoms, history of depression or on antidepressants (p = 0.000). In 32 women (21%) who scored > 15 on the CES-D, 72% had already suffered from a depressive state. Women with no history of depressive disorder scored more frequently above 15 when they were perimenopausal. CONCLUSION: This sample of climacteric women, from a non-specialized mental or menopausal health service, had low mean scores on the CES-D, with the item insomnia being the most highly scored. History of a previous depressive episode, but not the woman's climacteric period, was a risk factor for higher scores on the CES-D. In the group of women with no history of depression, the perimenopausal women had more scores above the cut-point. This fact may suggest that the perimenopause is a period of higher susceptibility to new onset of depressive episodes.
简介:本研究的目的是使用美国国家心理健康研究所流行病学研究中心抑郁量表(CES-D)评估更年期妇女的抑郁症状。方法:这是一项在巴西里约热内卢妇科门诊进行的横断面研究,包括151名40至65岁的更年期妇女。使用CES-D评估抑郁症状,并通过结构化访谈获得社会人口学、临床和妇科数据。CES-D得分超过15分被认为是抑郁状态的分界点。结果:平均CES-D评分为9.2分(标准差= 9.0)。失眠、悲伤和沮丧的得分最高。除了有精神症状、抑郁史或服用抗抑郁药的女性外,CES-D评分与更年期、社会人口统计学、临床或妇科特征之间无显著相关性(p = 0.000)。在CES-D得分> 15分的32名女性(21%)中,72%已经患有抑郁状态。没有抑郁症病史的女性在围绝经期得分高于15分的几率更高。结论:来自非专业心理或绝经期健康服务机构的绝经期妇女样本在CES-D上的平均得分较低,其中失眠项目得分最高。以前的抑郁病史,而不是女性的更年期,是在CES-D上获得高分的一个危险因素。在没有抑郁史的妇女组中,围绝经期妇女的得分高于分界点。这一事实可能表明,围绝经期是一个更容易出现新发抑郁发作的时期。
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引用次数: 17
Patient informed consent in case reports: current practice in our country 病例报告中的患者知情同意:我国的现行做法
Pub Date : 2008-12-01 DOI: 10.1590/S0101-81082008000400004
Paulo Oscar Teitelbaum
* Psiquiatra, psicanalista. Editor, Rev Psiquiatr RS.Relatorio apresentado no Forum de Publicacoes – Ciencia e Etica em Publicacoes em Psiquiatria, XXVICongresso Brasileiro de Psiquiatria, Brasilia, realizado em outubro de 2008.Nao ha conflitos de interesse associados a publicacao deste editorial.Rev Psiquiatr RS. 2008;30(3):
*精神病学家,精神分析学家。在2008年10月巴西利亚举行的第二十六届巴西精神病学大会上发表的出版物论坛-精神病学出版物的科学和伦理报告。这篇社论的发表没有利益冲突。精神病学Rev . RS. 2008;30(3):
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引用次数: 0
Atualização das normas brasileiras para o International Affective Picture System (IAPS) 国际情感图片系统(IAPS)巴西标准的更新
Pub Date : 2008-12-01 DOI: 10.1590/S0101-81082008000400012
Cristina Lasaitis, Rafaela Larsen Ribeiro, M. Freire, Orlando Francisco Amodeo Bueno
This study includes the standardization of 240 new stimuli in the Brazilian norms for the International Affective Picture System (IAPS), an instrument of affective images widely used in research, and confirms the validity of the categories of "pleasant," "neutral" and "unpleasant" pictures. A comparison was performed of the scores of affective ratings between the male and female samples of university students (179 males, and 269 females), who assessed the affective content of photographs in terms of valence, arousal and dominance using the Self Assessment Manikin (SAM) scale. The methods were the same used in a study conducted for the American norms.
本研究包括对国际情感图像系统(IAPS)的巴西规范中的240个新刺激进行标准化,IAPS是一种广泛用于研究的情感图像工具,并证实了“愉快”,“中性”和“不愉快”图片类别的有效性。对大学生(179名男性和269名女性)的情感评分进行了比较,这些大学生使用自我评估模型(SAM)量表从效价、唤醒和支配度三个方面对照片的情感内容进行了评估。这些方法与为美国规范进行的一项研究相同。
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引用次数: 10
Avaliação da qualidade de vida de acadêmicos de graduação em Enfermagem do primeiro e quarto anos: influência das variáveis sociodemográficas 一、四年级护理本科生生活质量评价:社会人口学变量的影响
Pub Date : 2008-12-01 DOI: 10.1590/S0101-81082008000400010
Rosane Bueno Eurich, A. C. Kluthcovsky
INTRODUCTION: The aim of this study was to evaluate the quality of life of undergraduate students from a nursing course in a public university in the State of Parana, Brazil, correlating with sociodemographic variables, and to compare undergraduate students from first and fourth years. METHOD: This is a descriptive and cross-sectional study with a quantitative approach. Thirty-four students (89.5%) from the first year and 33 (100%) from the fourth year participated. They answered the WHOQOL-bref, a questionnaire designed by the World Health Organization, in addition to some additional information. RESULTS: The students were predominantly female, young and single, with per capita family income up to one minimum wage, coming from other cities and living with the family or with housemates. Considering the entire sample, the highest quality of life mean score was for the physical domain (72.7 + 13.1), and the lowest for the environment domain (60.7 + 12.7). Correlation with sociodemographic variables showed that only gender had significant correlation with quality of life. The highest mean scores were for male students in the physical (79.9 + 9.8) and psychological (77.6 + 6.3) domains. There was significant difference between age and income in the comparison between students from first and fourth years, the profile of first-year students being younger and with low income than students from the fourth year. In spite of this, no significant difference in quality of life domains was found. CONCLUSION: The results of this study suggest that nursing students need attention in relation to the quality of life, especially women in the physical and psychological aspects.
前言:本研究的目的是评估巴西巴拉那州一所公立大学护理专业本科生的生活质量,与社会人口学变量相关,并比较一年级和四年级的本科生。方法:这是一项定量方法的描述性和横断面研究。大一学生34人(89.5%),大四学生33人(100%)。除了提供一些补充资料外,他们还回答了世界卫生组织设计的问卷whoqol - brief。结果:受访学生以女性为主,年轻,单身,人均家庭收入不超过一个最低工资标准,来自其他城市,与家人或室友一起生活。考虑到整个样本,生活质量平均得分最高的是物理领域(72.7 + 13.1),最低的是环境领域(60.7 + 12.7)。与社会人口学变量的相关性显示,只有性别与生活质量有显著相关。平均分最高的是男生的生理(79.9 + 9.8)和心理(77.6 + 6.3)。一年级学生和四年级学生的年龄和收入存在显著差异,一年级学生比四年级学生年龄小、收入低。尽管如此,在生活质量方面没有发现显著差异。结论:本研究结果提示护生在生活质量方面需要注意,尤其是女性在生理和心理方面。
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引用次数: 34
期刊
Boletim Geografico do Rio Grande do Sul
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