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Use of ivabradine in postoperative junctional ectopic tachycardia: A systematic review of case series and case reports 伊伐布雷定在术后交界性异位心动过速中的应用:病例系列和病例报告的系统回顾
Q4 Medicine Pub Date : 2021-01-01 DOI: 10.4103/heartindia.heartindia_47_20
Dhruva Sharma, G. Subramaniam, N. Sharma, Preksha Sharma
Purpose: When tachyarrhythmias originates from atrioventricular (AV) node, AV junction or bundle of His complex, they are termed “junctional ectopic tachycardia” (JET). Cardiac surgeries especially involving crux of the heart are mainly responsible for JET. Amiodarone and other pharmaco-therapeutic agents are tried as antiarrhythmics for the treatment of postoperative JET. Aim of this review was to discuss about role of ivabradine in the treatment of postoperative JET. Materials and Methods: A search was carried out for this review article on the basis of literature available including scientific databases of PubMed, Embase, Scopus, Google Scholar, using keywords “Ivabradine,” “Postoperative junctional ectopic tachycardia,” “Arrhythmias,” “Funny currents,” from October 2011 to October 2020. Results: After initial screening of 377 articles, 9 studies were included and discussed in detail in the present review article. Conclusion: Treatment of choice of postoperative JET is still not well established. Although there are very few case reports and case series that have been reported on the use of ivabradine in JET, yet it seems to offer a promising use.
目的:当快速性心律失常起源于房室结、房室结或希氏复合体束时,称为“交界性异位性心动过速”(JET)。心脏手术,特别是涉及心脏的关键是主要负责JET。胺碘酮和其他药物治疗剂被用作抗心律失常药物,用于治疗术后JET。本综述的目的是讨论伊伐布雷定在术后JET治疗中的作用。材料和方法:2011年10月至2020年10月,在PubMed、Embase、Scopus、Google Scholar的科学数据库等现有文献的基础上,使用关键词“Ivabradine”、“术后交界性异位心动过速”、“心律失常”、“Funny currents”搜索这篇综述文章。结果:在对377篇文章进行初步筛选后,纳入了9项研究,并在本综述文章中进行了详细讨论。结论:术后JET的治疗选择尚不明确。尽管很少有关于伊伐布雷定在JET中使用的病例报告和病例系列报告,但它似乎提供了一种有前景的用途。
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引用次数: 0
Delayed perforation of the right ventricle by pacemaker/automated implantable cardioverter-defibrillator lead: A single-center experience 由起搏器/自动植入式心律转复除颤器导联引起的延迟右心室穿孔:单中心体验
Q4 Medicine Pub Date : 2021-01-01 DOI: 10.4103/heartindia.heartindia_43_20
Sarvesh Kumar, Vivek Tewarson, M. Hakim, Shobhit Kumar, S. Singh
Introduction: Cardiac perforation by pacemaker/automatic implantable cardioverter-defibrillator (AICD) lead can be a life-threatening emergency. Delayed cardiac perforation by pacemaker/AICD lead is defined as perforation occurring after a period of 1 month following pacemaker/AICD insertion. Delayed perforation is often difficult to identify at first and needs active intervention to prevent complications and death. Materials and Methods: Patients presenting with and operated upon for delayed cardiac perforation following pacemaker/AICD insertion were included in this study. The study was conducted between April 2019 and April 2020. Results: Three patients reported with delayed cardiac perforation after pacemaker insertion. All patients had syncopal episodes, and detection could be easily done using chest X-ray and trans-thoracic echocardiography (TTE). Two patients had active fixation leads used for anchoring the lead in the right ventricle (RV). Two patients were female, while one was a male, and all had perforation through the RV apex. Lead reposition was done in two cases, thereby preventing the need for placing additional leads, while a new lead was required in the third case. Conclusion: Early identification of cardiac perforation can be done easily with chest X-ray and TTE, but a high index of suspicion should be kept in mind. Surgical or fluoroscopic intervention may be planned depending on the available expertise and patient condition.
引言:起搏器/自动植入式心律转复除颤器(AICD)导线导致心脏穿孔可能是危及生命的紧急情况。起搏器/AICD导线引起的延迟性心脏穿孔定义为起搏器/AICD插入后1个月后发生的穿孔。延迟性穿孔通常一开始很难识别,需要积极干预以防止并发症和死亡。材料和方法:本研究包括植入起搏器/AICD后出现延迟性心脏穿孔并进行手术的患者。该研究于2019年4月至2020年4月期间进行。结果:3例患者报告植入起搏器后出现延迟性心脏穿孔。所有患者都有合乳症发作,使用胸部X光和经胸超声心动图(TTE)可以很容易地进行检测。两名患者使用主动固定导线将导线固定在右心室(RV)。两名患者为女性,一名为男性,均为右心室尖部穿孔。在两种情况下进行了导线重新定位,从而避免了放置额外导线的需要,而在第三种情况下需要新导线。结论:胸部X线片和经胸超声心动图可以很容易地早期识别心脏穿孔,但应注意高怀疑指数。根据可用的专业知识和患者状况,可以计划进行手术或荧光透视干预。
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引用次数: 0
Clinical features and treatment outcomes of cardiomyopathy in Indian patients: An observational, retrospective study in tertiary care teaching institute 印度患者心肌病的临床特征和治疗结果:一项在三级保健教学机构进行的观察性、回顾性研究
Q4 Medicine Pub Date : 2021-01-01 DOI: 10.4103/heartindia.heartindia_42_20
A. Jawahirani, Deepak Jeswani, Dilip Kshirsagar, Rajnish Dhediya, Amit Y Jadhav
Objective: Cardiomyopathy is defined as a heterogeneous group of diseases of the myocardium, is a transient reversible, but potentially life-threatening condition. The natural history, management pattern, and outcome of cardiomyopathy are not clear in Indian scenario. This study was conducted to investigate the clinical features, prognostic predictors, and clinical outcomes of patients with cardiomyopathy. Materials and Methods: We retrospectively analyzed the data of 119 patients of cardiomyopathy admitted to tertiary care hospital from January 2016 to April 2019. Results: The mean age of analyzed patients was 55.08 ± 15.75 years. During admission, symptoms such as breathlessness (63.64%) and fever (40.17%) were reported more often than other symptoms. 38.66% of patients had dilated and stress cardiomyopathy while 15.97% had ischemic cardiomyopathy. Among the independent predictors of all cause death the respiratory failure, sepsis and renal dysfunction were identified. Reduced ejection fraction in 73%, moderate-to-severe mitral regurgitation in 20%, and global hypokinesia in 68.57% patients were observed. Of total admissions, 86% of patients recovered while 14% patients resulted in death. Conclusion: Our study shows that respiratory failure, sepsis, anemia, and renal failure are major contributing factors in poor prognosis, although most of the patients recovered from cardiomyopathy. Cardiomyopathy is the one of the important causes for heart failure with reduced ejection fraction.
目的:心肌病被定义为一组异质性心肌疾病,是一种短暂可逆但可能危及生命的疾病。在印度,心肌病的自然史、管理模式和结果尚不清楚。本研究旨在探讨心肌病患者的临床特征、预后预测因素和临床结果。材料与方法:我们回顾性分析了2016年1月至2019年4月入住三级医院的119例心肌病患者的数据。结果:分析患者的平均年龄为55.08±15.75岁。入院期间,呼吸困难(63.64%)和发烧(40.17%)等症状的报告频率高于其他症状。38.66%的患者患有扩张型和应激型心肌病,15.97%的患者患有缺血性心肌病。在全因死亡的独立预测因素中,确定了呼吸衰竭、败血症和肾功能障碍。射血分数降低73%,中度至重度二尖瓣反流20%,全身运动功能减退68.57%。在总入院人数中,86%的患者康复,14%的患者死亡。结论:我们的研究表明,呼吸衰竭、败血症、贫血和肾功能衰竭是预后不良的主要因素,尽管大多数患者已从心肌病中康复。心肌病是射血分数降低的心力衰竭的重要原因之一。
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引用次数: 0
Acute high-risk pulmonary embolism following spine surgery successfully treated by pharmaco-mechanical intervention 药物机械干预成功治疗脊柱手术后急性高危肺栓塞
Q4 Medicine Pub Date : 2020-07-01 DOI: 10.4103/heartindia.heartindia_39_20
B. Kumar, A. Kodliwadmath, A. Upadhyay, Anupam Singh, N. Nanda
Acute high-risk pulmonary embolism (PE) is defined as PE with either cardiac arrest, obstructive shock, or persistent hypotension at presentation. The incidence of venous thromboembolism (VTE) is lower following spine surgery compared to joint arthroplasty surgeries. The use of anticoagulants after spine surgery for the prevention of VTE is associated with a definite risk of epidural hematoma resulting in neurologic sequelae. Here, we report a case of a 57-year-old female who presented with cardio-respiratory arrest following spine surgery due to acute high-risk PE. In view of recent spine surgery and traumatic cardiopulmonary resuscitation, which are considered as contraindications for systemic thrombolysis and unavailability of cardiac surgery unit, the patient was treated with pharmaco-mechanical intervention resulting in successful recovery with no development of epidural hematoma or neurologic sequelae. Prophylactic anticoagulation for the prevention of VTE and the risk of epidural hematoma should be balanced after a case of spine surgery.
急性高危肺栓塞(PE)是指出现心脏骤停、阻塞性休克或持续性低血压的PE。与关节置换术相比,脊柱手术后静脉血栓栓塞症(VTE)的发生率较低。脊柱手术后使用抗凝剂预防VTE与硬膜外血肿导致神经后遗症的明确风险有关。在这里,我们报告了一例57岁的女性,她在脊椎手术后因急性高危PE而出现心肺骤停。鉴于最近的脊椎手术和创伤性心肺复苏被认为是全身溶栓的禁忌症和心脏手术室的不可用,患者接受了药物-机械干预治疗,成功康复,没有出现硬膜外血肿或神经后遗症。预防性抗凝预防VTE和硬膜外血肿的风险应在脊柱手术后得到平衡。
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引用次数: 0
Impact of coronavirus disease 2019 lockdown on catheterization laboratory: An Indian perspective 2019年冠状病毒病封锁对导尿实验室的影响:印度视角
Q4 Medicine Pub Date : 2020-07-01 DOI: 10.4103/heartindia.heartindia_28_20
A. Singh, R. Nath, A. Raj, N. Pandit, P. Aggarwal, A. Thakur, R. Bharadwaj, Vinod Kumar, Kritika Singh
Aims: This study aims to study the impact of coronavirus disease 2019 (COVID-19) lockdown on catheterization laboratory (Cath Lab) utilization for cardiac patients. Subjects and Methods: In this retrospective observational study, a total number of procedures in Cath Lab during COVID-19 lockdown were compared with pre-COVID-19 lockdown time to see the impact of the pandemic on cardiac patients undergoing interventions. Results: A total of 1982 procedures (1788 in prelockdown vs. 194 in lockdown; P < 0.001) were performed in the catheterization laboratory during the 6 months' time frame of this study. There was an alarming drop in procedures by 89.1% in the lockdown period with the maximum reduction seen in diagnostic coronary angiography (96.6%), elective angioplasty decreased by 96.4%, and primary angioplasty by 82.08%. There was an increase in rescue angioplasty by 80% (P < 0.001) during the lockdown phase. There was a fall of 83.9% in admissions of acute coronary syndrome and 62.76% reduction in heart failure admissions during the lockdown period. During the study period, there were a total of 2111 admissions in the cardiac care unit (1882 in pre vs. 229 in lockdown; P < 0.001), which showed an 87.14% reduction when compared to the prelockdown group. Conclusions: We report an alarming reduction in total admissions and catheterization laboratory procedures as an impact of COVID-19-related lockdown. This represents a serious problem regarding the handling of this pandemic by the health-care system and can be used to devise proper strategies for the recovery phase of the COVID-19 pandemic.
目的:本研究旨在研究2019冠状病毒病(COVID-19)封锁对心脏患者导管实验室(Cath Lab)利用的影响。对象和方法:在这项回顾性观察性研究中,将COVID-19封锁期间Cath实验室的手术总数与COVID-19封锁前的时间进行比较,以了解大流行对接受干预的心脏病患者的影响。结果:共有1982例手术(封前1788例对封后194例;P < 0.001)在本研究的6个月时间框架内在导尿实验室进行。在封锁期间,手术次数下降了89.1%,其中诊断性冠状动脉造影下降幅度最大(96.6%),选择性血管成形术下降了96.4%,初次血管成形术下降了82.08%。在封锁阶段,抢救血管成形术增加了80% (P < 0.001)。在封锁期间,急性冠状动脉综合征入院率下降83.9%,心力衰竭入院率下降62.76%。在研究期间,共有2111人入住心脏监护室(术前为1882人,封锁期为229人;P < 0.001),与封锁前组相比,减少了87.14%。结论:我们报告,受covid -19相关封锁的影响,入院总人数和实验室导尿程序出现了惊人的减少。这是卫生保健系统处理此次大流行的一个严重问题,可用于为COVID-19大流行的恢复阶段制定适当的战略。
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引用次数: 0
Correlation of HbA1c with coronary flow velocity and disease severity in chronic stable angina 慢性稳定型心绞痛患者HbA1c与冠脉血流速度及病情严重程度的相关性
Q4 Medicine Pub Date : 2020-07-01 DOI: 10.4103/heartindia.heartindia_26_20
Abad Khan, A. Rashid, I. Wani, M. Iqbal, I. Hafeez, N. Tramboo, Aizaz Lone, Shaista Jamil
Introduction: Increasing hemoglobin A1c (HbA1c) levels in individuals with and without diabetes mellitus are risk factors for cardiovascular events and atherosclerosis. Aims and Objectives: The aim and objective was to study the association of HbA1c with coronary flow velocity (CFV). Materials and Methods: This was a single-center, hospital-based, nonrandomized, prospective observational study. All consecutive patients admitted in the department of cardiology with the diagnosis of chronic stable angina who underwent coronary angiography from April 1, 2017, to October 31, 2018, were subjected to the eligibility criteria. The patients were divided into the four HbA1c quartiles based on the HbA1c at hospital admission: Group A (HbA1c < 5.2%), Group B (HbA1c: 5.2–5.6), Group C (HbA1c: 5.7–6.4), and Group D (HbA1c: ≥6.5%). Corrected TIMI frame count (TFC) was used to assess the CFV. The severity of coronary artery disease (CAD) was studied by Gensini score. Results: A total of 263 consecutive patients with a mean age of 56.71 ± 10.59 years were included. Nearly 70% (n = 184) of the patients were males. The mean HbA1c was statistically significantly higher in obstructive CAD versus nonobstructive versus no CAD (6.06 vs. 5.63 vs. 5.23) (P < 0.001). Increasing HbA1c among all quartiles was statistically significantly associated with increasing TFC in all coronary arteries (left anterior descending artery [LAD] 30.32 vs. 34.05 vs. 36.72 vs. 36.94; left circumflex artery [LCX] 19.89 vs. 22.41 vs. 24.05 vs. 23.76; right coronary artery [RCA] 19.42 vs. 22.02 vs. 23.24 vs. 23.50, respectively, for the four HbA1c quartiles; P < 0.001). HbA1c had a significant linear correlation with TFC of LAD, LCX, and RCA (r = 0.6, 0.54, and 0.51, respectively). Among the various quartiles of HbA1c, CAD was significantly more common in patients with higher HbA1c values (P < 0.0001) (1.03% vs. 33.89% vs. 73.33% vs. 82.35%, respectively). The mean Gensini score increased with increasing HbA1c quartiles (0.40 vs. 4.68 vs. 21.63 vs. 30.52, respectively, P < 0.001). Conclusion: HbA1c has a significant association with CFV even in subdiabetic range. However, the therapeutic strategies and benefit of lower HbA1c in nondiabetic patients are still uncertain. Large randomized trials are needed to address this issue.
引言:糖尿病患者和非糖尿病患者的血红蛋白A1c水平升高是心血管事件和动脉粥样硬化的危险因素。目的和目的:研究HbA1c与冠状动脉血流速度(CFV)的关系。材料和方法:这是一项单中心、以医院为基础、非随机、前瞻性观察性研究。自2017年4月1日至2018年10月31日,心脏科连续收治的所有诊断为慢性稳定型心绞痛并接受冠状动脉造影的患者均符合资格标准。根据入院时的HbA1c,将患者分为四个HbA1c四分位数:A组(HbA1c<5.2%)、B组(HbA1c:5.2-5.6)、C组(HbAlc:5.7-64)和D组(HbHbA1c:≥6.5%)。使用校正的TIMI帧计数(TFC)来评估CFV。用Gensini评分研究冠心病的严重程度。结果:共纳入263例连续患者,平均年龄56.71±10.59岁。近70%(n=184)的患者为男性。梗阻性CAD患者的平均HbA1c显著高于非梗阻性CAD(6.06 vs.5.63 vs.5.23)(P<0.001)。所有四分位数中HbA1c的增加与所有冠状动脉中TFC的增加具有统计学意义(左前降支[LAD]30.32 vs.34.05 vs.36.72 vs.36.94;左旋支[LCX]19.89对22.41对24.05对23.76;四个HbA1c四分位数的右冠状动脉[RCA]分别为19.42对22.02对23.24对23.50;P<0.001)。HbA1c与LAD、LCX和RCA的TFC呈显著的线性相关(r分别为0.6、0.54和0.51)。在不同的HbA1c四分位数中,CAD在HbA1c值较高的患者中明显更常见(P<0.0001)(分别为1.03%对33.89%对73.33%对82.35%)。平均Gensini评分随HbA1c四分位数的增加而增加(分别为0.40对4.68对21.63对30.52,P<0.001)。然而,降低非糖尿病患者HbA1c的治疗策略和益处仍不确定。需要进行大规模的随机试验来解决这个问题。
{"title":"Correlation of HbA1c with coronary flow velocity and disease severity in chronic stable angina","authors":"Abad Khan, A. Rashid, I. Wani, M. Iqbal, I. Hafeez, N. Tramboo, Aizaz Lone, Shaista Jamil","doi":"10.4103/heartindia.heartindia_26_20","DOIUrl":"https://doi.org/10.4103/heartindia.heartindia_26_20","url":null,"abstract":"Introduction: Increasing hemoglobin A1c (HbA1c) levels in individuals with and without diabetes mellitus are risk factors for cardiovascular events and atherosclerosis. Aims and Objectives: The aim and objective was to study the association of HbA1c with coronary flow velocity (CFV). Materials and Methods: This was a single-center, hospital-based, nonrandomized, prospective observational study. All consecutive patients admitted in the department of cardiology with the diagnosis of chronic stable angina who underwent coronary angiography from April 1, 2017, to October 31, 2018, were subjected to the eligibility criteria. The patients were divided into the four HbA1c quartiles based on the HbA1c at hospital admission: Group A (HbA1c < 5.2%), Group B (HbA1c: 5.2–5.6), Group C (HbA1c: 5.7–6.4), and Group D (HbA1c: ≥6.5%). Corrected TIMI frame count (TFC) was used to assess the CFV. The severity of coronary artery disease (CAD) was studied by Gensini score. Results: A total of 263 consecutive patients with a mean age of 56.71 ± 10.59 years were included. Nearly 70% (n = 184) of the patients were males. The mean HbA1c was statistically significantly higher in obstructive CAD versus nonobstructive versus no CAD (6.06 vs. 5.63 vs. 5.23) (P < 0.001). Increasing HbA1c among all quartiles was statistically significantly associated with increasing TFC in all coronary arteries (left anterior descending artery [LAD] 30.32 vs. 34.05 vs. 36.72 vs. 36.94; left circumflex artery [LCX] 19.89 vs. 22.41 vs. 24.05 vs. 23.76; right coronary artery [RCA] 19.42 vs. 22.02 vs. 23.24 vs. 23.50, respectively, for the four HbA1c quartiles; P < 0.001). HbA1c had a significant linear correlation with TFC of LAD, LCX, and RCA (r = 0.6, 0.54, and 0.51, respectively). Among the various quartiles of HbA1c, CAD was significantly more common in patients with higher HbA1c values (P < 0.0001) (1.03% vs. 33.89% vs. 73.33% vs. 82.35%, respectively). The mean Gensini score increased with increasing HbA1c quartiles (0.40 vs. 4.68 vs. 21.63 vs. 30.52, respectively, P < 0.001). Conclusion: HbA1c has a significant association with CFV even in subdiabetic range. However, the therapeutic strategies and benefit of lower HbA1c in nondiabetic patients are still uncertain. Large randomized trials are needed to address this issue.","PeriodicalId":32147,"journal":{"name":"Heart India","volume":"8 1","pages":"127 - 132"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43783765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Adult interrupted aortic arch with aortic regurgitation: Single-stage repair 成人主动脉弓中断伴主动脉反流:一期修复
Q4 Medicine Pub Date : 2020-07-01 DOI: 10.4103/heartindia.heartindia_35_20
C. Srivastava, Ranajit B Naik, Sunil D. Sharma, P. Goyal
Adult patients with interruption of the aorta are an extremely rare occurrence. It is commonly associated with additional cardiovascular anomalies. Surgery is the mainstay in the management of the patients. Interrupted aortic arch and associated cardiac disease is a complex situation that requires correction either simultaneously or in stages. We describe the case of a 32-year-old male patient planned for aortic valve replacement at another center, incidentally diagnosed with interrupted aortic arch Type A. He was managed with single-stage aortic valve replacement and extra-anatomical bypass.
成人主动脉中断是极为罕见的。它通常与其他心血管异常有关。外科手术是治疗这些病人的主要手段。主动脉弓中断和相关的心脏疾病是一种复杂的情况,需要同时或分阶段进行纠正。我们描述了一个32岁的男性患者计划在另一个中心进行主动脉瓣置换术,偶然被诊断为a型主动脉弓中断,他接受了单期主动脉瓣置换术和解剖外搭桥治疗。
{"title":"Adult interrupted aortic arch with aortic regurgitation: Single-stage repair","authors":"C. Srivastava, Ranajit B Naik, Sunil D. Sharma, P. Goyal","doi":"10.4103/heartindia.heartindia_35_20","DOIUrl":"https://doi.org/10.4103/heartindia.heartindia_35_20","url":null,"abstract":"Adult patients with interruption of the aorta are an extremely rare occurrence. It is commonly associated with additional cardiovascular anomalies. Surgery is the mainstay in the management of the patients. Interrupted aortic arch and associated cardiac disease is a complex situation that requires correction either simultaneously or in stages. We describe the case of a 32-year-old male patient planned for aortic valve replacement at another center, incidentally diagnosed with interrupted aortic arch Type A. He was managed with single-stage aortic valve replacement and extra-anatomical bypass.","PeriodicalId":32147,"journal":{"name":"Heart India","volume":"8 1","pages":"144 - 147"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43406249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short-term outcomes of left main coronary artery disease treatment: A comparative study of optimal medical therapy, coronary artery bypass grafting, and percutaneous coronary intervention 左主干冠状动脉疾病治疗的短期疗效:最佳药物治疗、冠状动脉搭桥术和经皮冠状动脉介入治疗的比较研究
Q4 Medicine Pub Date : 2020-07-01 DOI: 10.4103/heartindia.heartindia_23_20
P. Vishwakarma, Raj N Sharma, A. Pradhan, M. Bhandari, R. Sethi, Akhil Sharma, S. Chandra, G. Chaudhary, S. Dwivedi, V. Narain
Background: Several studies have compared treatment strategies in patients with left main coronary artery (LMCA) disease. However, short-term outcomes have scarcely been reported. Materials and Methods: In this prospective, single-center, descriptive study, conducted between January 1, 2017, and January 1, 2018, patients with LMCA disease were treated through medical follow-up (MFU), percutaneous coronary intervention (PCI), or coronary artery bypass grafting (CABG). Results: A total of 149 patients participated in the study. Of the 149 patients, 27 (18.1%), 69 (46.3%), and 53 (35.6%) patients were treated with CABG, MFU, and PCI, respectively. The SYNTAX score was 31.0 ± 5.8, 29.9 ± 7.0, and 21.0 ± 6.8 in the CABG, MFU, and PCI groups (P<0.001), respectively. At the 6-month follow-up, 19 (76.0%) and 38 (76.0%) patients presented with New York Heart Association (NYHA) Class I dyspnea in the CABG and PCI groups, respectively, as compared to 29 (59.2%) patients in the MFU group (P = 0.139). Similarly, 22 (88.0%) and 43 (86.0%) patients presented with NYHA Class I angina in the CABG and PCI groups, respectively, as compared to 27 (55.1%) patients in the MFU group (P = 0.033). Death occurred in 1 (3.7%), 10 (17.2%), and 2 (3.8%) patients in the CABG, MFU, and PCI groups (P = 0.033), respectively. Diabetics accounted for 9/13 (69.2%) of the patients who died (P = 0.012). Conclusion: Optimal medical therapy did not provide any 6-month survival benefits in patients with LMCA disease. However, CABG and PCI present as suitable treatment options for this subset of patients. The majority of the patients who presented with dyspnea and NYHA Class I belonged to the PCI and CABG groups.
背景:几项研究比较了左主干冠状动脉(LMCA)疾病患者的治疗策略。然而,短期结果几乎没有报道。材料和方法:在2017年1月1日至2018年1月1日进行的这项前瞻性、单中心、描述性研究中,LMCA疾病患者通过医学随访(MFU)、经皮冠状动脉介入治疗(PCI)或冠状动脉旁路移植术(CABG)进行治疗。结果:共有149例患者参与研究。149例患者中,分别有27例(18.1%)、69例(46.3%)和53例(35.6%)患者接受了CABG、MFU和PCI治疗。CABG组、MFU组、PCI组SYNTAX评分分别为31.0±5.8、29.9±7.0、21.0±6.8 (P<0.001)。在6个月的随访中,CABG组和PCI组分别有19例(76.0%)和38例(76.0%)患者出现纽约心脏协会(NYHA) I级呼吸困难,而MFU组有29例(59.2%)患者出现呼吸困难(P = 0.139)。同样,CABG和PCI组分别有22例(88.0%)和43例(86.0%)患者出现NYHA I级心绞痛,而MFU组有27例(55.1%)患者出现NYHA I级心绞痛(P = 0.033)。CABG组、MFU组和PCI组分别有1例(3.7%)、10例(17.2%)和2例(3.8%)患者死亡(P = 0.033)。死亡患者中糖尿病患者占9/13 (69.2%)(P = 0.012)。结论:最佳药物治疗并没有为LMCA患者提供任何6个月的生存益处。然而,对于这部分患者,冠脉搭桥和PCI是合适的治疗选择。出现呼吸困难和NYHA I级的患者多数属于PCI组和CABG组。
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引用次数: 0
Mitral valve assessment and scoring before balloon mitral valvuloplasty 球囊二尖瓣成形术前二尖瓣评估与评分
Q4 Medicine Pub Date : 2020-07-01 DOI: 10.4103/heartindia.heartindia_22_20
Satyam Rajvanshi, R. Nath, R. Bharadwaj
Management of symptomatic rheumatic mitral stenosis (MS) by nonsurgical techniques has been the therapeutic modality of choice in low- and middle-income countries such as India. In comparison to surgical interventions, catheter-based balloon dilatation has been preferred in cases of rheumatic MS. Various scoring systems, including three-dimensional (3D), 2D transthoracic, and transesophageal echo and fluoroscopy, have been summarized in this review for the evaluation of the morphology of the valve apparatus, including calcification, and subvalvular involvement for predicting favorable outcomes.
在印度等中低收入国家,通过非手术技术治疗有症状的风湿性二尖瓣狭窄(MS)一直是首选的治疗方式。与手术干预相比,在风湿性多发性硬化症的病例中,基于导管的球囊扩张是首选。本综述总结了各种评分系统,包括三维(3D)、二维经胸和经食道回声和荧光镜检查,用于评估瓣膜装置的形态,包括钙化,以及瓣膜下受累以预测良好结果。
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引用次数: 1
CytoSorb in the management of severe septic shock after coronary artery bypass graft surgery CytoSorb在冠状动脉搭桥术后严重感染性休克治疗中的应用
Q4 Medicine Pub Date : 2020-07-01 DOI: 10.4103/heartindia.heartindia_45_19
A. Prakash, V. Garg, D. Mittal, A. Upadhyay
Achieving sufficient adsorption of increased immune mediators with the help of hemadsorption has been a breakthrough discovery in the field of cardiac sciences. Any surgery, injury, or trauma causes the release of pro-inflammatory mediators, which may trigger a severe systemic inflammatory response syndrome (SIRS) and multiorgan failure. Septic shock after major cardiac surgeries is a feared complication, which increases mortality and morbidity and contributes to prolonged hospitalization. CytoSorb has been widely used worldwide in patients with septic shock as well as in postsurgery SIRS. This is a case of acute septic shock that developed after coronary artery bypass graft and which was efficiently managed using CytoSorb hemoadsorber.
在血液吸附的帮助下实现对增加的免疫介质的充分吸附是心脏科学领域的一项突破性发现。任何手术、损伤或创伤都会导致促炎介质的释放,这可能引发严重的系统性炎症反应综合征(SIRS)和多器官衰竭。心脏大手术后感染性休克是一种令人恐惧的并发症,它会增加死亡率和发病率,并导致住院时间延长。在脓毒性休克和术后SIRS患者中,CytoSorb已被广泛应用。这是一例急性感染性休克,发生在冠状动脉搭桥术后,并有效地管理使用CytoSorb吸附剂。
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引用次数: 1
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Heart India
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