首页 > 最新文献

Indian Journal of Pain最新文献

英文 中文
Expect the Unexpected!! – Transient Cranial Nerve Palsies after Radiofrequency Ablation of Gasserian Ganglion for Trigeminal Neuralgia 期待意想不到的结果- 三叉神经痛加塞神经节射频消融术后的短暂颅神经麻痹
Pub Date : 2023-09-27 DOI: 10.4103/ijpn.ijpn_129_22
Pratibha Matche, Prabhakar Sathiah, S. Paneyala, Aishwarya Bajaj
Trigeminal neuralgia is the most common type of craniofacial neuralgia, characterized by paroxysmal lancinating electric shock-like pain confined to the somatosensory distribution of the trigeminal nerve. Fluoroscopy-guided Radiofrequency Ablation of Gasserian Ganglion (RFA-GG) is the commonly performed minimally invasive pain intervention in these patients. Various complications such as masseter weakness, corneal anesthesia, dysesthesia, anesthesia dolorosa, keratitis, and cranial nerve deficits have been reported during the procedure. We present the case of a 58-year-old male diagnosed with left-sided trigeminal neuralgia involving mandibular division of trigeminal nerve (V3 division) with a Numerical Rating Scale of 9/10 at the time of presentation. As the patient was unresponsive to medical management, RFA of the V3 division of GG was performed with acceptable sensory and motor stimulation. Postablation, 1 ml of 1.0% Lidocaine injection with 2 mg injection dexamethasone was given. After the procedure, the patient complained of dizziness, left-sided hearing loss, and double vision on looking toward the left side. On examination, deviation of the angle of the mouth toward the right side, reduced blink reflex on the left side, and incomplete closure of the left eyelid were observed. Vitals were stable and there was no respiratory discomfort. The patient was reassured and monitored in the recovery room. Signs and symptoms were transient and the patient recovered completely after 45 min. Clinical findings were suggestive of the involvement of three cranial nerves: the abducens nerve, the facial nerve, and the vestibulocochlear nerve. Spillage of local anesthetic solution into adjacent cranial nerves surrounding the GG might be the causative mechanism for transient cranial nerve palsies in this case.
三叉神经痛是颅面神经痛中最常见的一种,其特征是局限于三叉神经躯体感觉分布区的阵发性阵发性电击样疼痛。透视引导下的加瑟神经节射频消融术(RFA-GG)是此类患者常用的微创疼痛干预方法。据报道,手术过程中会出现各种并发症,如咀嚼肌无力、角膜麻醉、失调性麻醉、角膜炎和颅神经功能缺损。我们报告了一例 58 岁男性的病例,患者被诊断为左侧三叉神经痛,涉及三叉神经下颌分部(V3 分部),就诊时的数字评分表为 9/10。由于患者对药物治疗无反应,因此在可接受的感觉和运动刺激下对三叉神经 V3 分部进行了射频消融术。消融术后注射了 1 毫升 1.0% 利多卡因和 2 毫克地塞米松。术后,患者主诉头晕、左侧听力下降、看左侧时出现重影。检查时发现患者口角偏向右侧,左侧眨眼反射减弱,左眼睑闭合不全。生命体征平稳,无呼吸道不适。在恢复室对患者进行了安抚和监护。体征和症状均为一过性,45 分钟后患者完全康复。临床结果表明有三条颅神经受累:外展神经、面神经和前庭神经。局麻药溶液溢入 GG 周围邻近的颅神经可能是本病例一过性颅神经麻痹的致病机制。
{"title":"Expect the Unexpected!! – Transient Cranial Nerve Palsies after Radiofrequency Ablation of Gasserian Ganglion for Trigeminal Neuralgia","authors":"Pratibha Matche, Prabhakar Sathiah, S. Paneyala, Aishwarya Bajaj","doi":"10.4103/ijpn.ijpn_129_22","DOIUrl":"https://doi.org/10.4103/ijpn.ijpn_129_22","url":null,"abstract":"Trigeminal neuralgia is the most common type of craniofacial neuralgia, characterized by paroxysmal lancinating electric shock-like pain confined to the somatosensory distribution of the trigeminal nerve. Fluoroscopy-guided Radiofrequency Ablation of Gasserian Ganglion (RFA-GG) is the commonly performed minimally invasive pain intervention in these patients. Various complications such as masseter weakness, corneal anesthesia, dysesthesia, anesthesia dolorosa, keratitis, and cranial nerve deficits have been reported during the procedure. We present the case of a 58-year-old male diagnosed with left-sided trigeminal neuralgia involving mandibular division of trigeminal nerve (V3 division) with a Numerical Rating Scale of 9/10 at the time of presentation. As the patient was unresponsive to medical management, RFA of the V3 division of GG was performed with acceptable sensory and motor stimulation. Postablation, 1 ml of 1.0% Lidocaine injection with 2 mg injection dexamethasone was given. After the procedure, the patient complained of dizziness, left-sided hearing loss, and double vision on looking toward the left side. On examination, deviation of the angle of the mouth toward the right side, reduced blink reflex on the left side, and incomplete closure of the left eyelid were observed. Vitals were stable and there was no respiratory discomfort. The patient was reassured and monitored in the recovery room. Signs and symptoms were transient and the patient recovered completely after 45 min. Clinical findings were suggestive of the involvement of three cranial nerves: the abducens nerve, the facial nerve, and the vestibulocochlear nerve. Spillage of local anesthetic solution into adjacent cranial nerves surrounding the GG might be the causative mechanism for transient cranial nerve palsies in this case.","PeriodicalId":32328,"journal":{"name":"Indian Journal of Pain","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139335363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraperitoneal instillation of bupivacaine and hydrocortisone for postoperative analgesia in laparoscopic cholecystectomy under spinal anaesthesia – A prospective randomized study 腹腔注射布比卡因和氢化可的松用于脊髓麻醉下腹腔镜胆囊切除术术后镇痛的前瞻性随机研究
Pub Date : 2023-05-01 DOI: 10.4103/ijpn.ijpn_88_22
Rajabhau Kshirsagar, S. Kuttarmare, P. Bhalerao, Sujit Kshirsagar
Background: Laparoscopic cholecystectomy is a minimally invasive procedure requiring less hospital stay and early mobilization as compared to open procedure. The aim of our study was to compare the efficacy of intraperitoneal instillation of hydrocortisone with bupivacaine for postoperative analgesia in patients undergoing laparoscopic cholecystectomy under spinal anesthesia. Materials and Methods: Sixty patients were enrolled in this prospective randomized study. Patients either received 0.125% bupivacaine (Group B) or 0.125% bupivacaine with 100 mg hydrocortisone (Group H) through intraperitoneal drain at the end of surgery. Pain was evaluated every two hourly using the Visual Analog Scale (VAS) for 24 h. Analgesics were required during this period and the presence of shoulder pain was also noted. Results: Patients in the hydrocortisone group had lower pain scores (2.17 ± 0.47) compared to the bupivacaine group (3.51 ± 1.10). This difference in the mean VAS score was statistically significant (P < 0.01). Similarly, patients requiring rescue analgesia were 60.86% in Group B and 39.14% in Group H and were statistically significant. Time for rescue analgesia was longer in Group H as compared to Group B. Conclusion: Intraperitoneal bupivacaine and hydrocortisone decrease pain and analgesic requirements more effectively than bupivacaine alone after laparoscopic cholecystectomy without causing significant adverse effects.
背景:腹腔镜胆囊切除术是一种微创手术,与开放手术相比,需要更少的住院时间和早期动员。本研究的目的是比较脊髓麻醉下腹腔镜胆囊切除术患者腹腔滴注氢化可的松和布比卡因的术后镇痛效果。材料和方法:60名患者被纳入这项前瞻性随机研究。患者在手术结束时通过腹膜内引流接受0.125%布比卡因(B组)或0.125%布哌卡因和100mg氢化可的松(H组)。使用视觉模拟量表(VAS)每两小时评估一次疼痛,持续24小时。在此期间需要镇痛,并注意到肩部疼痛。结果:与布比卡因组(3.51±1.10)相比,氢化可的松组患者的疼痛评分(2.17±0.47)较低。平均VAS评分的差异具有统计学意义(P<0.01)。同样,B组需要抢救性镇痛的患者为60.86%,H组为39.14%,具有统计学意义。与B组相比,H组的抢救镇痛时间更长。结论:腹腔镜胆囊切除术后,腹膜内布比卡因和氢化可的松比单独布比卡因更有效地降低疼痛和镇痛需求,不会造成显著的不良反应。
{"title":"Intraperitoneal instillation of bupivacaine and hydrocortisone for postoperative analgesia in laparoscopic cholecystectomy under spinal anaesthesia – A prospective randomized study","authors":"Rajabhau Kshirsagar, S. Kuttarmare, P. Bhalerao, Sujit Kshirsagar","doi":"10.4103/ijpn.ijpn_88_22","DOIUrl":"https://doi.org/10.4103/ijpn.ijpn_88_22","url":null,"abstract":"Background: Laparoscopic cholecystectomy is a minimally invasive procedure requiring less hospital stay and early mobilization as compared to open procedure. The aim of our study was to compare the efficacy of intraperitoneal instillation of hydrocortisone with bupivacaine for postoperative analgesia in patients undergoing laparoscopic cholecystectomy under spinal anesthesia. Materials and Methods: Sixty patients were enrolled in this prospective randomized study. Patients either received 0.125% bupivacaine (Group B) or 0.125% bupivacaine with 100 mg hydrocortisone (Group H) through intraperitoneal drain at the end of surgery. Pain was evaluated every two hourly using the Visual Analog Scale (VAS) for 24 h. Analgesics were required during this period and the presence of shoulder pain was also noted. Results: Patients in the hydrocortisone group had lower pain scores (2.17 ± 0.47) compared to the bupivacaine group (3.51 ± 1.10). This difference in the mean VAS score was statistically significant (P < 0.01). Similarly, patients requiring rescue analgesia were 60.86% in Group B and 39.14% in Group H and were statistically significant. Time for rescue analgesia was longer in Group H as compared to Group B. Conclusion: Intraperitoneal bupivacaine and hydrocortisone decrease pain and analgesic requirements more effectively than bupivacaine alone after laparoscopic cholecystectomy without causing significant adverse effects.","PeriodicalId":32328,"journal":{"name":"Indian Journal of Pain","volume":"37 1","pages":"110 - 114"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43675687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison among intrathecal nalbuphine and fentanyl in combination with chloroprocaine 1% for short surgical lower limb procedures – A prospective randomized control trial 鞘内注射纳洛酮和芬太尼联合1%氯普鲁卡因用于下肢短手术的比较——一项前瞻性随机对照试验
Pub Date : 2023-05-01 DOI: 10.4103/ijpn.ijpn_97_22
Priti Sherikar, Minna Osheen, M. Mitragotri, Arunima Gangadhar
Background: Preservative-free chloroprocaine (CP) 1% is being investigated for short surgeries but lacks immediate postoperative analgesia. Adding opioids to local anesthetic increases the quality of spinal anesthesia with prolongation of postoperative analgesia. Aim: The aim of this study is to compare the postoperative analgesic efficacy of intrathecal nalbuphine versus intrathecal fentanyl as an adjuvant to chlorprocaine 1% for short surgical lower limb procedures. Materials and Methods: After ethical committee approval, a prospective randomized double-blind comparative study was conducted on 90 patients of the American Society of Anesthesiologists classes 1 and 2, aged between 18 and 60 years who were scheduled for elective short surgical lower limb procedures. Group CP (n = 30) received CP 1% 40 mg (4 ml) plus saline (0.5 ml), Group CP with fentanyl (CF) (n = 30) received CP 1% 40 mg (4 ml) plus fentanyl 25 mcg (0.5 ml), and Group CP with nalbuphine (CN) (n = 30) received CP 1% 40 mg (4 ml) plus nalbuphine 0.8 mg (0.5 ml) intrathecally. After performing subarachnoid block, the parameters observed were – Onset, height, duration of sensory and motor blockade, duration of postoperative analgesia, hemodynamics, and adverse effects between the three groups noted. Results: The onset of sensory and motor block (min) is faster in Group CF (4.2 ± 0.2, 3.4 ± 0.4) compared to Group CN (4.8 ± 0.4, 3.7 ± 0.4) and Group CP (6.2 ± 0.4, 4 ± 0.4) (P < 0.001). The total sensory duration and motor duration are prolonged in Group CN (96.5 ± 5.2, 90 ± 3.9) compared to Group CF (94 ± 4, 87 ± 4.5) and Group CP (77 ± 3, 74 ± 4.5) (P < 0.001). The duration of postoperative analgesia was prolonged in Group CN (130 ± 5.3) compared to Group CF (111 ± 6.2) and Group C (93 ± 4.2) (P < 0.001). Conclusion: We conclude that intrathecal nalbuphine prolongs postoperative analgesia maximally compared to intrathecal fentanyl as an adjuvant to CP 1% for short surgical lower limb procedures.
背景:1%不含防腐剂的氯普鲁卡因(CP)用于短期手术,但缺乏术后立即镇痛。在局部麻醉剂中加入阿片类药物可以延长术后镇痛时间,从而提高脊麻的质量。目的:本研究的目的是比较鞘内注射纳尔布芬与鞘内注射芬太尼作为1%氯丙卡因辅助剂在短时间下肢手术中的术后镇痛效果。材料和方法:在伦理委员会批准后,对90名美国麻醉师学会1级和2级患者进行了一项前瞻性随机双盲比较研究,这些患者年龄在18至60岁之间,计划接受选择性短期下肢手术。CP组(n=30)鞘内注射CP1%40mg(4ml)加生理盐水(0.5ml),含芬太尼(CF)的CP组(n=30。蛛网膜下腔阻滞后,观察到的参数为:发病时间、身高、感觉和运动阻滞持续时间、术后镇痛持续时间、血液动力学以及三组间的不良反应。结果:与CN组(4.8±0.4,3.7±0.4)和CP组(6.2±0.4,4±0.4)相比,CF组(4.2±0.2,3.4±0.4)的感觉和运动阻滞(min)的发作更快(P<0.001)CN组术后镇痛时间(130±5.3)比CF组(111±6.2)和C组(93±4.2)延长(P<0.001)。
{"title":"Comparison among intrathecal nalbuphine and fentanyl in combination with chloroprocaine 1% for short surgical lower limb procedures – A prospective randomized control trial","authors":"Priti Sherikar, Minna Osheen, M. Mitragotri, Arunima Gangadhar","doi":"10.4103/ijpn.ijpn_97_22","DOIUrl":"https://doi.org/10.4103/ijpn.ijpn_97_22","url":null,"abstract":"Background: Preservative-free chloroprocaine (CP) 1% is being investigated for short surgeries but lacks immediate postoperative analgesia. Adding opioids to local anesthetic increases the quality of spinal anesthesia with prolongation of postoperative analgesia. Aim: The aim of this study is to compare the postoperative analgesic efficacy of intrathecal nalbuphine versus intrathecal fentanyl as an adjuvant to chlorprocaine 1% for short surgical lower limb procedures. Materials and Methods: After ethical committee approval, a prospective randomized double-blind comparative study was conducted on 90 patients of the American Society of Anesthesiologists classes 1 and 2, aged between 18 and 60 years who were scheduled for elective short surgical lower limb procedures. Group CP (n = 30) received CP 1% 40 mg (4 ml) plus saline (0.5 ml), Group CP with fentanyl (CF) (n = 30) received CP 1% 40 mg (4 ml) plus fentanyl 25 mcg (0.5 ml), and Group CP with nalbuphine (CN) (n = 30) received CP 1% 40 mg (4 ml) plus nalbuphine 0.8 mg (0.5 ml) intrathecally. After performing subarachnoid block, the parameters observed were – Onset, height, duration of sensory and motor blockade, duration of postoperative analgesia, hemodynamics, and adverse effects between the three groups noted. Results: The onset of sensory and motor block (min) is faster in Group CF (4.2 ± 0.2, 3.4 ± 0.4) compared to Group CN (4.8 ± 0.4, 3.7 ± 0.4) and Group CP (6.2 ± 0.4, 4 ± 0.4) (P < 0.001). The total sensory duration and motor duration are prolonged in Group CN (96.5 ± 5.2, 90 ± 3.9) compared to Group CF (94 ± 4, 87 ± 4.5) and Group CP (77 ± 3, 74 ± 4.5) (P < 0.001). The duration of postoperative analgesia was prolonged in Group CN (130 ± 5.3) compared to Group CF (111 ± 6.2) and Group C (93 ± 4.2) (P < 0.001). Conclusion: We conclude that intrathecal nalbuphine prolongs postoperative analgesia maximally compared to intrathecal fentanyl as an adjuvant to CP 1% for short surgical lower limb procedures.","PeriodicalId":32328,"journal":{"name":"Indian Journal of Pain","volume":"37 1","pages":"115 - 119"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46528693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aberrant branch of vertebral artery: A needling challenge for ultrasound-guided stellate ganglion block 椎动脉异常分支:超声引导星状神经节阻滞的针刺挑战
Pub Date : 2023-05-01 DOI: 10.4103/ijpn.ijpn_21_23
P. Singh, D. Bhoi
{"title":"Aberrant branch of vertebral artery: A needling challenge for ultrasound-guided stellate ganglion block","authors":"P. Singh, D. Bhoi","doi":"10.4103/ijpn.ijpn_21_23","DOIUrl":"https://doi.org/10.4103/ijpn.ijpn_21_23","url":null,"abstract":"","PeriodicalId":32328,"journal":{"name":"Indian Journal of Pain","volume":"37 1","pages":"136 - 137"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44392967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pain education among government school children in West Bengal, India: A report 印度西孟加拉邦公立学校儿童的疼痛教育:一份报告
Pub Date : 2023-05-01 DOI: 10.4103/ijpn.ijpn_76_22
S. Goswami, G. Nandi, S. Basu
{"title":"Pain education among government school children in West Bengal, India: A report","authors":"S. Goswami, G. Nandi, S. Basu","doi":"10.4103/ijpn.ijpn_76_22","DOIUrl":"https://doi.org/10.4103/ijpn.ijpn_76_22","url":null,"abstract":"","PeriodicalId":32328,"journal":{"name":"Indian Journal of Pain","volume":"37 1","pages":"131 - 133"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47936777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An analysis of patients with chronic pain amid COVID-19 pandemic: A cross-sectional observational trial 新冠肺炎大流行期间慢性疼痛患者的分析:一项横断面观察性试验
Pub Date : 2023-05-01 DOI: 10.4103/ijpn.ijpn_128_22
V. Ahuja, D. Thapa, S. Mitra, Kushagrita Singh, Lekshmi V. Nair
Context: The unpredictable nature of COVID-19 pandemic and the limited patient–doctor interaction led to the change in chronic pain management during the pandemic. Aims: The study aimed to compare pain scores and bio-psycho-social aspects of chronic pain in patients during prepandemic versus COVID-19 pandemic period. Settings and Designs: This was a prospective, cross-sectional observational trial conducted in a tertiary care hospital. Subjects and Methods: The study was conducted between September 2021 and January 2022 which corresponded with the end of the second wave and beginning of the third wave of COVID-19 pandemic. A set of 20 web-based questionnaires were sent to adult patients of both genders and who had visited pain clinic before the onset of pandemic. Statistical Analysis Use: Discrete categorical data were presented as n (%); continuous data were written either in the form of its mean and standard deviation or in the form of its median and interquartile range. All statistical tests were two-sided and were performed at a significance level of P < 0.05. Results: A total of 408 patients of chronic pain participated in the web-based questionnaire. The most common diagnosis was low back pain, facial pain, and knee pain. The patients continued to consume analgesics during the pandemic, had ≥2 burnout score, and reported “poor to fair” quality of sleep score. During the pandemic, pain score increased in those subsets of patients who earlier had no pain (odds ratio [OR]: 68.33, confidence interval [CI]: 24.10–193.72, P = 0.000), mild pain (OR: 22.78, CI: 9.49–54.64, P = 0.000), and moderate pain. On the contrary, chronic pain decreased or remained same in the population having moderate or severe pain before the pandemic. Patients with increased pain during the pandemic wanted the outpatient department to reopen for consultation with pain physician. The majority of the patients 350 (85.78%) who had participated in the study did not suffer from COVID-19 infection. Conclusions: Regular intake of analgesics during the COVID-19 pandemic reduced the number of patients experiencing severe pain. However, the patients suffering from moderate-to-severe pain during the pandemic had a direct correlation between higher pain severity and poor quality of sleep.
背景:新冠肺炎大流行的不可预测性和有限的患者与医生互动导致了大流行期间慢性疼痛管理的变化。目的:该研究旨在比较大流行前和新冠肺炎大流行期间患者的疼痛评分和慢性疼痛的生物-心理-社会方面。设置和设计:这是一项在三级护理医院进行的前瞻性、横断面观察性试验。受试者和方法:该研究于2021年9月至2022年1月进行,当时正值新冠肺炎第二波疫情结束和第三波疫情开始。向在疫情爆发前去过疼痛诊所的男女成年患者发送了一组20份基于网络的问卷。统计分析使用:离散分类数据以n(%)表示;连续数据要么以平均值和标准差的形式书写,要么以中位数和四分位间距的形式书写。所有的统计检验都是双侧的,并且在显著性水平上进行了P<0.05。结果:共有408名慢性疼痛患者参加了基于网络的问卷调查。最常见的诊断是腰痛、面部疼痛和膝盖疼痛。患者在疫情期间继续服用止痛药,倦怠评分≥2分,并报告睡眠质量评分“较差至尚可”。在疫情期间,早期没有疼痛(比值比[OR]:68.33,置信区间[CI]:24.10–193.72,P=0.000)、轻度疼痛(OR:22.78,CI:9.49–54.64,P=0.0000)和中度疼痛的患者亚群的疼痛评分增加。相反,在大流行之前,中度或重度疼痛的人群中,慢性疼痛减少或保持不变。疫情期间疼痛加剧的患者希望门诊部重新开放,咨询疼痛医生。参与研究的350名患者中的大多数(85.78%)没有感染新冠肺炎。结论:在新冠肺炎大流行期间定期服用止痛药减少了严重疼痛的患者人数。然而,在疫情期间遭受中度至重度疼痛的患者,疼痛严重程度较高与睡眠质量差之间存在直接相关性。
{"title":"An analysis of patients with chronic pain amid COVID-19 pandemic: A cross-sectional observational trial","authors":"V. Ahuja, D. Thapa, S. Mitra, Kushagrita Singh, Lekshmi V. Nair","doi":"10.4103/ijpn.ijpn_128_22","DOIUrl":"https://doi.org/10.4103/ijpn.ijpn_128_22","url":null,"abstract":"Context: The unpredictable nature of COVID-19 pandemic and the limited patient–doctor interaction led to the change in chronic pain management during the pandemic. Aims: The study aimed to compare pain scores and bio-psycho-social aspects of chronic pain in patients during prepandemic versus COVID-19 pandemic period. Settings and Designs: This was a prospective, cross-sectional observational trial conducted in a tertiary care hospital. Subjects and Methods: The study was conducted between September 2021 and January 2022 which corresponded with the end of the second wave and beginning of the third wave of COVID-19 pandemic. A set of 20 web-based questionnaires were sent to adult patients of both genders and who had visited pain clinic before the onset of pandemic. Statistical Analysis Use: Discrete categorical data were presented as n (%); continuous data were written either in the form of its mean and standard deviation or in the form of its median and interquartile range. All statistical tests were two-sided and were performed at a significance level of P < 0.05. Results: A total of 408 patients of chronic pain participated in the web-based questionnaire. The most common diagnosis was low back pain, facial pain, and knee pain. The patients continued to consume analgesics during the pandemic, had ≥2 burnout score, and reported “poor to fair” quality of sleep score. During the pandemic, pain score increased in those subsets of patients who earlier had no pain (odds ratio [OR]: 68.33, confidence interval [CI]: 24.10–193.72, P = 0.000), mild pain (OR: 22.78, CI: 9.49–54.64, P = 0.000), and moderate pain. On the contrary, chronic pain decreased or remained same in the population having moderate or severe pain before the pandemic. Patients with increased pain during the pandemic wanted the outpatient department to reopen for consultation with pain physician. The majority of the patients 350 (85.78%) who had participated in the study did not suffer from COVID-19 infection. Conclusions: Regular intake of analgesics during the COVID-19 pandemic reduced the number of patients experiencing severe pain. However, the patients suffering from moderate-to-severe pain during the pandemic had a direct correlation between higher pain severity and poor quality of sleep.","PeriodicalId":32328,"journal":{"name":"Indian Journal of Pain","volume":"37 1","pages":"91 - 105"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45535840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sympathetic blocks for the treatment of chronic pelvic/perineal pain secondary to recurrent urinary tract infection 交感神经阻滞治疗复发性尿路感染继发的慢性盆腔/会阴疼痛
Pub Date : 2023-05-01 DOI: 10.4103/ijpn.ijpn_60_22
M. Pruthi, G. Chanana, Meenu Walia
Interventional management of pain has been described as the 4th step of the WHO analgesic ladder and proves immensely useful for many refractory and resistant pains. Recurrent urinary tract infection (UTI) can lead to chronic pelvic and perineal pain, which are often refractory to analgesics including strong opioids, and requires centrally acting neuropathic pain medications, along with psychological and behavioral therapies, and may need interventional pain management. Sympathetic nerve blocks are indicated and can be used in management of visceral pain/cancer pain. A patient with cancer may experience pain due to cancer, side effects of its treatment, or a noncancer pathology. They are prone to recurrent infections including urinary tract, respiratory tract, bloodstream infections, among others, which become a common cause of morbidity and mortality in patients with cancer. In this case report, the authors present a case with advanced cancer in whom recurrent UTI led to chronic debilitating perineal pain which was successfully managed with superior hypogastric plexus and ganglion impar block highlighting the potential utility of these underutilized blocks in challenging situations of complex pelvic and perineal pains.
疼痛的介入治疗被描述为世界卫生组织止痛阶梯的第四步,并被证明对许多顽固性疼痛非常有用。复发性尿路感染(UTI)可导致慢性骨盆和会阴疼痛,这些疼痛通常对包括强效阿片类药物在内的止痛药难以治疗,需要集中作用的神经性疼痛药物以及心理和行为治疗,可能需要介入性疼痛管理。交感神经阻滞是指可用于内脏疼痛/癌症疼痛的治疗。癌症患者可能会因癌症、其治疗的副作用或非癌症病理而感到疼痛。他们容易反复感染,包括尿路、呼吸道、血液感染等,这已成为癌症患者发病和死亡的常见原因。在本病例报告中,作者介绍了一例晚期癌症患者,其中复发性UTI导致慢性削弱性会阴部疼痛,并通过腹下上丛和神经节穿刺阻滞成功治疗,突出了这些未充分利用的阻滞在复杂骨盆和会阴部痛的挑战性情况下的潜在效用。
{"title":"Sympathetic blocks for the treatment of chronic pelvic/perineal pain secondary to recurrent urinary tract infection","authors":"M. Pruthi, G. Chanana, Meenu Walia","doi":"10.4103/ijpn.ijpn_60_22","DOIUrl":"https://doi.org/10.4103/ijpn.ijpn_60_22","url":null,"abstract":"Interventional management of pain has been described as the 4th step of the WHO analgesic ladder and proves immensely useful for many refractory and resistant pains. Recurrent urinary tract infection (UTI) can lead to chronic pelvic and perineal pain, which are often refractory to analgesics including strong opioids, and requires centrally acting neuropathic pain medications, along with psychological and behavioral therapies, and may need interventional pain management. Sympathetic nerve blocks are indicated and can be used in management of visceral pain/cancer pain. A patient with cancer may experience pain due to cancer, side effects of its treatment, or a noncancer pathology. They are prone to recurrent infections including urinary tract, respiratory tract, bloodstream infections, among others, which become a common cause of morbidity and mortality in patients with cancer. In this case report, the authors present a case with advanced cancer in whom recurrent UTI led to chronic debilitating perineal pain which was successfully managed with superior hypogastric plexus and ganglion impar block highlighting the potential utility of these underutilized blocks in challenging situations of complex pelvic and perineal pains.","PeriodicalId":32328,"journal":{"name":"Indian Journal of Pain","volume":"37 1","pages":"123 - 127"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43701075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two-arm observational study to assess the efficacy of cooled versus conventional radiofrequency ablation of medial branch nerves in patients with lumbar facet joint arthropathy 评估冷却与常规射频消融治疗腰椎小关节病患者内侧支神经疗效的双臂观察研究
Pub Date : 2023-05-01 DOI: 10.4103/ijpn.ijpn_13_23
Swati Saroha, Dipasri Bhattacharya, P. Arya, Arpita Choudhury, Rajasree Biswas
Background: Pain originating in the facet joint accounts for an estimated 15%–45% of cases of low back pain. Radiofrequency ablation (RFA) of the medial branch nerves (MBN) is used in refractory cases. However, very few studies have compared the clinical outcomes of cooled versus conventional/traditional RFA (T-RFA) for the treatment of lumbar facet joint pain. Objective: To determine the clinical outcomes of MBN cooled RFA (C-RFA) compared with T-RFA, as measured by improvements in pain and physical function. Methodology: Forty patients with positive diagnostic MBN blocks were allocated to C-RFA or T-RFA group. Reduction in pain (NRS “Numerical Rating Scale” score), improvement in quality of life (Oswestry Disability Index [ODI]), proportion of responders/successful treatment (≥50% NRS reduction, and or ≥30% or ≥15 point reduction in ODI at 6 months follow up) in the two groups were recorded. Results: Total 34 patients were analysed, C-RFA (n = 18) and T-RFA (n = 16). There was significant reduction in pain scores as well as improvement in quality of life in both the groups, but the difference between the two groups was not significant. NRS reduction of ≥50% was observed in 72.22% and 68.5% of participants in the C-RFA and T-RFA groups, respectively (P = 0.824). A ≥15-point or ≥30% reduction in ODI score was observed in 77.77% and 75% of participants in the C-RFA and T-RFA groups, respectively (P = 0.849). Conclusions: Both the groups showed significant improvement in pain scores and quality of life. C-RFA resulted in greater treatment success rate than conventional RFA, but the difference was not significant.
背景:起源于小关节的疼痛估计占腰痛病例的15%-45%。内侧支神经(MBN)的射频消融(RFA)用于难治性病例。然而,很少有研究比较冷却与传统/传统RFA(T-RFA)治疗腰椎小关节疼痛的临床结果。目的:通过疼痛和身体功能的改善来确定MBN冷却RFA(C-RFA)与T-RFA的临床结果。方法:将40例诊断MBN阻滞阳性的患者分为C-RFA组或T-RFA组。记录两组患者的疼痛减轻(NRS“数字评定量表”评分)、生活质量改善(Oswestry残疾指数[ODI])、有反应者/成功治疗的比例(在6个月的随访中,NRS减少≥50%,ODI减少≥30%或≥15分)。结果:共分析34例患者,C-RFA(n=18)和T-RFA(n=16)。两组患者的疼痛评分均显著降低,生活质量也有所改善,但两组之间的差异并不显著。C-RFA和T-RFA组分别有72.22%和68.5%的参与者NRS降低≥50%(P=0.824)。C-RFA组和T-RFA组分别有77.77%和75%的参与者ODI评分降低≥15分或≥30%(P=0.849)。结论:两组的疼痛评分和生活质量均显著改善。C-RFA的治疗成功率高于传统RFA,但差异不显著。
{"title":"Two-arm observational study to assess the efficacy of cooled versus conventional radiofrequency ablation of medial branch nerves in patients with lumbar facet joint arthropathy","authors":"Swati Saroha, Dipasri Bhattacharya, P. Arya, Arpita Choudhury, Rajasree Biswas","doi":"10.4103/ijpn.ijpn_13_23","DOIUrl":"https://doi.org/10.4103/ijpn.ijpn_13_23","url":null,"abstract":"Background: Pain originating in the facet joint accounts for an estimated 15%–45% of cases of low back pain. Radiofrequency ablation (RFA) of the medial branch nerves (MBN) is used in refractory cases. However, very few studies have compared the clinical outcomes of cooled versus conventional/traditional RFA (T-RFA) for the treatment of lumbar facet joint pain. Objective: To determine the clinical outcomes of MBN cooled RFA (C-RFA) compared with T-RFA, as measured by improvements in pain and physical function. Methodology: Forty patients with positive diagnostic MBN blocks were allocated to C-RFA or T-RFA group. Reduction in pain (NRS “Numerical Rating Scale” score), improvement in quality of life (Oswestry Disability Index [ODI]), proportion of responders/successful treatment (≥50% NRS reduction, and or ≥30% or ≥15 point reduction in ODI at 6 months follow up) in the two groups were recorded. Results: Total 34 patients were analysed, C-RFA (n = 18) and T-RFA (n = 16). There was significant reduction in pain scores as well as improvement in quality of life in both the groups, but the difference between the two groups was not significant. NRS reduction of ≥50% was observed in 72.22% and 68.5% of participants in the C-RFA and T-RFA groups, respectively (P = 0.824). A ≥15-point or ≥30% reduction in ODI score was observed in 77.77% and 75% of participants in the C-RFA and T-RFA groups, respectively (P = 0.849). Conclusions: Both the groups showed significant improvement in pain scores and quality of life. C-RFA resulted in greater treatment success rate than conventional RFA, but the difference was not significant.","PeriodicalId":32328,"journal":{"name":"Indian Journal of Pain","volume":"37 1","pages":"86 - 90"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46816661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erector spinae plane block for cancer pain – A scoping review of current evidence 直立脊柱平面阻滞治疗癌性疼痛-当前证据的范围综述
Pub Date : 2023-05-01 DOI: 10.4103/ijpn.ijpn_54_23
Indubala Maurya, R. Saxena, R. Maurya
Cancer patients experience pain secondary to the disease process or due to treatment. Refractory cancer pain can present a clinical challenge for pain physicians, which significantly affects patients' quality of life and increases disability. Erector spinae plane (ESP) blocks have rapidly been used in both acute and chronic pain practice. However, the use of ESP block for cancer pain management remains unclear. Thus, we conducted this scoping review to perform a comprehensive overview of current evidence on ESP block for cancer pain management. We searched the PubMed and Google Scholar databases for relevant articles published between January 2016 and March 2023 using the keywords “erector spinae plane block,” “ESP block,” and “cancer pain”. After excluding duplicate and irrelevant articles, we included a total of 26 studies, which were case reports, case series, cohort studies, and randomized control trials. Both neurolytic and non-neurolytic ESP blocks were used for cancer pain. The ESP blocks were performed in all patients with severe pain (Visual Analog Score or Numerical Rating Scale >7) and the majority of cases had some degree of pain relief. None of the studies has reported any serious complications related to procedure or drug used. There was heterogeneity in the type of drug, volume, and concentration used for ESP block. A definitive conclusion regarding the efficacy and safety of ESP block in cancer pain management was not possible. The current literature suggests that the ESP block can be helpful in cancer pain management. However, caution must be exercised not to overestimate the safety of either neurolytic or non-neurolytic ESP block as 88% (n = 23) of included studies were either case reports or case series. Randomized controlled clinical trials are warranted to establish the efficacy and safety of ESP block in cancer pain management.s
癌症患者经历的疼痛继发于疾病过程或由于治疗。难治性癌性疼痛对疼痛医生来说是一个临床挑战,它显著影响患者的生活质量并增加残疾。竖脊平面(ESP)阻滞已迅速应用于急性和慢性疼痛的实践。然而,ESP阻滞在癌症疼痛管理中的应用仍不清楚。因此,我们进行了这一范围审查,对目前关于ESP阻滞治疗癌症疼痛的证据进行了全面的概述。我们检索了PubMed和谷歌Scholar数据库,检索了2016年1月至2023年3月期间发表的相关文章,关键词为“直立脊柱平面阻滞”、“ESP阻滞”和“癌症疼痛”。在排除重复和不相关的文章后,我们共纳入了26项研究,包括病例报告、病例系列、队列研究和随机对照试验。神经性和非神经性ESP阻滞均用于治疗癌性疼痛。所有有严重疼痛的患者(视觉模拟评分或数值评定量表bbb70)都进行了ESP阻滞,大多数病例都有一定程度的疼痛缓解。没有一项研究报告与手术或药物使用有关的严重并发症。用于ESP阻滞的药物类型、体积和浓度存在异质性。关于ESP阻滞在癌症疼痛管理中的有效性和安全性的明确结论是不可能的。目前的文献表明,ESP阻滞可以帮助癌症疼痛管理。然而,必须谨慎,不要高估神经溶解性或非神经溶解性ESP阻滞的安全性,因为88% (n = 23)的纳入研究要么是病例报告,要么是病例系列。需要随机对照临床试验来确定ESP阻滞治疗癌症疼痛的有效性和安全性
{"title":"Erector spinae plane block for cancer pain – A scoping review of current evidence","authors":"Indubala Maurya, R. Saxena, R. Maurya","doi":"10.4103/ijpn.ijpn_54_23","DOIUrl":"https://doi.org/10.4103/ijpn.ijpn_54_23","url":null,"abstract":"Cancer patients experience pain secondary to the disease process or due to treatment. Refractory cancer pain can present a clinical challenge for pain physicians, which significantly affects patients' quality of life and increases disability. Erector spinae plane (ESP) blocks have rapidly been used in both acute and chronic pain practice. However, the use of ESP block for cancer pain management remains unclear. Thus, we conducted this scoping review to perform a comprehensive overview of current evidence on ESP block for cancer pain management. We searched the PubMed and Google Scholar databases for relevant articles published between January 2016 and March 2023 using the keywords “erector spinae plane block,” “ESP block,” and “cancer pain”. After excluding duplicate and irrelevant articles, we included a total of 26 studies, which were case reports, case series, cohort studies, and randomized control trials. Both neurolytic and non-neurolytic ESP blocks were used for cancer pain. The ESP blocks were performed in all patients with severe pain (Visual Analog Score or Numerical Rating Scale >7) and the majority of cases had some degree of pain relief. None of the studies has reported any serious complications related to procedure or drug used. There was heterogeneity in the type of drug, volume, and concentration used for ESP block. A definitive conclusion regarding the efficacy and safety of ESP block in cancer pain management was not possible. The current literature suggests that the ESP block can be helpful in cancer pain management. However, caution must be exercised not to overestimate the safety of either neurolytic or non-neurolytic ESP block as 88% (n = 23) of included studies were either case reports or case series. Randomized controlled clinical trials are warranted to establish the efficacy and safety of ESP block in cancer pain management.s","PeriodicalId":32328,"journal":{"name":"Indian Journal of Pain","volume":"37 1","pages":"74 - 80"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48488278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erector spinae plane block as a potential analgesic option in acute pancreatitis 竖脊肌平面阻滞作为急性胰腺炎的潜在镇痛选择
Pub Date : 2023-05-01 DOI: 10.4103/ijpn.ijpn_101_21
Samiksha Khanuja, J. Agarwal, S. Hussain, K. Batt
Pain management in patients with acute pancreatitis (AP) is mostly dominated by intravenous opioids. Besides their side effects, opioids also prolong the intensive care unit stay of the patient. The ultrasound-guided erector spinae plane block (ESPB) is an established intervention for postoperative analgesia. It is now also being studied for providing pain relief in AP. A lower thoracic ESPB targets sympathetic nerve fibers in addition to the dorsal and ventral rami through local anesthetic spread to the paravertebral space to provide both visceral and somatic analgesia. It could be an effective adjuvant as a part of multimodal analgesia and may significantly reduce overall opioid usage. We describe a case of AP where significant pain relief was achieved after administering a single-shot ESPB.
急性胰腺炎(AP)患者的疼痛管理主要是静脉注射阿片类药物。除了副作用外,阿片类药物还延长了患者在重症监护室的时间。超声引导下竖脊肌平面阻滞(ESPB)是一种公认的术后镇痛干预方法。它现在也在研究为AP提供疼痛缓解。下胸ESPB通过局部麻醉剂扩散到椎旁间隙,靶向除背侧和腹侧分支外的交感神经纤维,以提供内脏和躯体镇痛。作为多模式镇痛的一部分,它可能是一种有效的佐剂,并可能显著减少阿片类药物的总体使用。我们描述了一个AP病例,在给予单次ESPB后,疼痛得到了显著缓解。
{"title":"Erector spinae plane block as a potential analgesic option in acute pancreatitis","authors":"Samiksha Khanuja, J. Agarwal, S. Hussain, K. Batt","doi":"10.4103/ijpn.ijpn_101_21","DOIUrl":"https://doi.org/10.4103/ijpn.ijpn_101_21","url":null,"abstract":"Pain management in patients with acute pancreatitis (AP) is mostly dominated by intravenous opioids. Besides their side effects, opioids also prolong the intensive care unit stay of the patient. The ultrasound-guided erector spinae plane block (ESPB) is an established intervention for postoperative analgesia. It is now also being studied for providing pain relief in AP. A lower thoracic ESPB targets sympathetic nerve fibers in addition to the dorsal and ventral rami through local anesthetic spread to the paravertebral space to provide both visceral and somatic analgesia. It could be an effective adjuvant as a part of multimodal analgesia and may significantly reduce overall opioid usage. We describe a case of AP where significant pain relief was achieved after administering a single-shot ESPB.","PeriodicalId":32328,"journal":{"name":"Indian Journal of Pain","volume":"37 1","pages":"128 - 130"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48872776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Indian Journal of Pain
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1