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Percutaneous vertebroplasty in metastatic vertebral fracture: A retrospective cross-sectional study 经皮椎体成形术治疗转移性椎体骨折的回顾性横断面研究
Pub Date : 2022-12-01 DOI: 10.4103/ijpn.ijpn_103_22
S. Rastogi, A. Agarwal, Yasum Litin, N. Singh, Hitesh Patel
Introduction: Metastatic vertebral fractures (VF) commonly cause severe disabling pain in cancer patients. VFs are common among elderly patients and account for approximately 1.5 million per year in the general population. Objective: Bone metastasis, which is a second major cause of pathologic fracture, may lead to severe intolerable pain, life-threatening hypercalcemia, spinal cord compression, and immobility. The purpose of this study was to evaluate pain relief and improvement in quality of life (QOL) in patients with metastatic VF undergoing percutaneous vertebroplasty (PVP). Methods: Ten cancer patients having metastatic VF underwent PVP from July 2018 to August 2020. All demographic data, procedures, improvement in pain, and analgesic requirements of patients were taken from a computer data system and telephonic follow-up. Results: Majority of patients were suffering from carcinoma lung followed by carcinoma pancreas. The mean ± standard deviation of Visual Analog Scale preoperatively was 8.8 ± 1.35, reduced to 2.14 ± 2.11 at 6 months postoperatively, suggesting significant pain reduction. Eight patients had reduction in analgesic requirements and two did not require any analgesics postoperatively. During the entire follow-up, there was no delayed complication. Conclusion: PVP is an effective, safe, and minimally invasive procedure for treating painful metastatic vertebral compression fracture refractory to conservative treatments. It provides a marked reduction of pain, maintains mechanical stability of the vertebrae, and improves QOL.
简介:转移性椎体骨折(VF)在癌症患者中通常会引起严重的致残性疼痛。VFs在老年患者中很常见,在普通人群中每年约占150万。目的:骨转移是病理性骨折的第二大原因,可导致严重的不可忍受的疼痛、危及生命的高钙血症、脊髓压迫和不动。本研究的目的是评估接受经皮椎体成形术(PVP)的转移性VF患者的疼痛缓解和生活质量(QOL)的改善。方法:10例癌症转移性VF患者于2018年7月至2020年8月接受PVP。患者的所有人口统计数据、手术、疼痛改善和镇痛需求均来自计算机数据系统和电话随访。结果:大多数患者以肺癌为主,胰腺癌次之。术前视觉模拟量表的平均±标准差为8.8±1.35,术后6个月降至2.14±2.11,表明疼痛明显减轻。8名患者的镇痛需求减少,2名患者术后不需要任何止痛药。在整个随访过程中,没有出现延迟性并发症。结论:PVP是一种有效、安全、微创的治疗难治性转移性椎体压缩性骨折的方法。它能显著减轻疼痛,保持脊椎的机械稳定性,并提高生活质量。
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引用次数: 0
Minimally invasive pain and spine interventions for low backache 微创疼痛和脊椎介入治疗腰痛
Pub Date : 2022-12-01 DOI: 10.4103/ijpn.ijpn_122_22
Pravesh Kanthed, Nitika Vyas, Prateek Arora, Samarjit Dey
Various pain generators can lead to low backpain. It includes conditions affecting the muscles, lumbar spine, joints, traversing and exiting nerve roots etc. The IASP named 2021 the year as the Global Year About Back Pain, highlighting its importance. Multiple modalities exist for the treatment of conditions causing low-back pain, including non-pharmacological therapies, drugs, percutaneous minimally invasive techniques and surgeries. This review aims at providing a cursory view of the common ailments causing low backache and its corresponding minimally invasive techniques.
各种疼痛源都会导致腰痛。它包括影响肌肉、腰椎、关节、穿越和退出神经根等的情况。IASP将2021年命名为全球背痛年,强调了其重要性。治疗引起腰痛的疾病有多种方式,包括非药物治疗、药物、经皮微创技术和手术。这篇综述旨在提供引起腰痛的常见疾病及其相应的微创技术的粗略视图。
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引用次数: 0
Radiofrequency ablation in chronic pain syndromes: An evidence- and consensus-based indian society for the study of pain guidelines, 2022 慢性疼痛综合征的射频消融:基于证据和共识的印度社会疼痛指南研究,2022
Pub Date : 2022-12-01 DOI: 10.4103/ijpn.ijpn_123_22
G. Das, Pankaj N Surange, A. Agarwal, K. Kothari, Samarjit Dey, Karthic Babu Natarajan, Palak H. Mehta, G. Sharma, Uttam Siddhaye, Neeraj Jain, V. Mohan
Chronic pain is a frequent, intricate, and adverse condition that has a considerable influence on individuals and society at large. In India, its prevalence is around 20%. Although a spectrum of conservative treatment modalities is available, a significant proportion of patients with chronic pain syndromes remain refractory and require surgical intervention. In these groups of patients, radiofrequency ablation (RFA) techniques are safe minimally invasive treatments and provide significant and durable pain relief. Thus, we aimed to formulate the Indian Society for the Study of Pain (ISSP) guidelines for the management of chronic pain syndromes with various RFA techniques. An in-depth literature review by experts in Pain Medicine practising in India, was used to produce 16 statements across 4 common chronic pain syndromes, including knee pain, headache and facial pain, lumbar facet joint pain, and sacroiliac joint pain. The quality of evidence was assessed with the Third US Preventive Service Task Force guidance document and the strength of the recommendation was determined by the Delphi consensus process. The level of evidence for most of the statements was I. Moreover, for most statements, the level of agreement between the experts was good (≥80% of the experts). The ISSP guidelines for the management of chronic pain syndromes are developed by experts in pain medicine. For most of the statements, the highest level of evidence was available and inter-expert agreement was good. However, further high-quality research is required to formulate more inclusive guidelines in this evolving pain medicine speciality.
慢性疼痛是一种常见的、复杂的、不利的疾病,对个人和社会都有相当大的影响。在印度,其患病率约为20%。尽管有一系列的保守治疗方式可用,但很大一部分慢性疼痛综合征患者仍然难治性,需要手术干预。在这些患者中,射频消融(RFA)技术是安全的微创治疗,并提供显著和持久的疼痛缓解。因此,我们的目标是制定印度疼痛研究学会(ISSP)指南,用于使用各种RFA技术管理慢性疼痛综合征。由印度疼痛医学专家进行的深入文献综述,用于产生4种常见慢性疼痛综合征的16种陈述,包括膝关节疼痛、头痛和面部疼痛、腰椎小关节疼痛和骶髂关节疼痛。证据的质量由第三美国预防服务工作组指导文件评估,建议的强度由德尔菲共识过程确定。大多数陈述的证据等级为i。此外,对于大多数陈述,专家之间的一致程度很好(≥80%的专家)。慢性疼痛综合征管理的ISSP指南是由疼痛医学专家制定的。对于大多数陈述,可获得最高水平的证据,专家间的一致意见很好。然而,在这个不断发展的疼痛医学专业中,需要进一步的高质量研究来制定更具包容性的指导方针。
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引用次数: 1
Botulinum toxin application in erector spinae blockade for the management of myofascial syndrome in patients with fibromyalgia: A case series 肉毒毒素应用于竖脊肌阻滞治疗纤维肌痛患者肌筋膜综合征:一系列病例
Pub Date : 2022-12-01 DOI: 10.4103/ijpn.ijpn_66_22
German Rangel J, Karina Ortega A, Ximena Cediel C
Botulinum toxin (BoNT) is a type of bacterial exotoxin that has been included in medical practice for multiple purposes, one of which is pain management. Some of the proposed mechanisms state that BoNT can reduce neurogenic inflammation by blocking the discharge of neuropeptides, including substance P and calcitonin gene-related peptides. Here, we present three patients with myofascial syndrome and fibromyalgia whose main symptom was pain in the dorsal region, wherein BoNT administered in the erector spinae bilaterally provided prolonged pain relief.
肉毒杆菌毒素(BoNT)是一种细菌外毒素,已被纳入医疗实践的多种目的,其中之一是疼痛管理。一些提出的机制表明BoNT可以通过阻断神经肽(包括P物质和降钙素基因相关肽)的排放来减少神经源性炎症。在这里,我们报告了3例肌筋膜综合征和纤维肌痛的患者,其主要症状是背部疼痛,其中双侧竖脊肌BoNT治疗可延长疼痛缓解。
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引用次数: 0
Percutaneous treatment of trigeminal neuralgia: A narrative review 三叉神经痛的经皮治疗:叙述性综述
Pub Date : 2022-12-01 DOI: 10.4103/ijpn.ijpn_119_22
A. Agarwal, S. Rastogi, Neha Singh, Manish Singh, Yasum Litin, Sunny Bhasin
Background: Minimally invasive and percutaneous treatments are effective treatment options for idiopathic trigeminal neuralgia (TN).Objectives: Multiple approaches have been described for the treatment of TN. This narrative review has been done to evaluate the current literature on different percutaneous treatment options for TN and to determine whether anyone treatment is better. Methods: The literature through a search of PubMed and Google Scholar was done and the review of the citations of relevant literature, and the authors knowledge of the literature and activity in the field. The literature was reviewed to find the preferred technique of preferred percutaneous treatment by different investigators and the difference in the outcome and/or complications and side effects. Results: Multiple techniques of such as percutaneous retrogasserian glycerol rhizolysis (PRGR), radiofrequency thermal coagulation (RFTC), and percutaneous balloon compression (PBC) for idiopathic TN have been used by different researchers. Effective pain relief and improved quality of life have been reported to be achieved by all the approaches. RFTC has been the most extensively used method, but PBC has been found to be more suitable for corneal preservation in cases of ophthalmic (V1) division pain. The most common imaging method used by large number of researchers is fluoroscope, though few authors have recommended computed tomography scan guidance for placement of cannula in foramen ovale and Meckle's cave, especially in cases with difficult anatomy. Limitations: This review has focused only on percutaneous techniques used by pain physicians. Other techniques such as radiosurgery and gamma knife used by radiologists and neurologists are not included. Conclusions: minimally invasive and percutaneous treatments such as PRGR, RFTC, and PBC are effective methods for the treatment of idiopathic TN. Selection of approach is largely dependent on the pain physician's choice, experience, and equipment available and can be used interchangeably; although for V1 neuralgia, PBC has superiority due to the preservation of corneal reflex.
背景:微创和经皮治疗是治疗特发性三叉神经痛(TN)的有效选择。目的:已经描述了多种治疗TN的方法。本叙述性综述旨在评估当前关于不同经皮治疗TN的文献,并确定是否有人的治疗效果更好。方法:通过检索PubMed和Google Scholar进行文献检索,并对相关文献的引文、作者对该领域文献的认识和活动进行综述。对文献进行了回顾,以找出不同研究者首选的经皮治疗技术,以及结果和/或并发症和副作用的差异。结果:不同的研究人员使用了多种技术,如经皮气体后甘油根溶解术(PRGR)、射频热凝术(RFTC)和经皮球囊压缩术(PBC)治疗特发性TN。据报道,所有这些方法都能有效缓解疼痛,提高生活质量。RFTC是使用最广泛的方法,但PBC已被发现更适合在眼(V1)分裂疼痛的情况下保存角膜。许多研究人员使用的最常见的成像方法是荧光透视,尽管很少有作者建议在卵圆孔和Meckle洞穴中放置套管时使用计算机断层扫描指导,尤其是在解剖困难的情况下。局限性:本综述仅关注疼痛医生使用的经皮技术。放射科医生和神经学家使用的放射外科和伽玛刀等其他技术不包括在内。结论:微创和经皮治疗,如PRGR、RFTC和PBC是治疗特发性TN的有效方法。方法的选择在很大程度上取决于疼痛医生的选择、经验和可用的设备,并且可以互换使用;尽管对于V1神经痛,PBC由于保留了角膜反射而具有优势。
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引用次数: 0
Fluoroscopic landmarks related to gasserian ganglion intervention 与加氏神经节干预相关的荧光标记
Pub Date : 2022-12-01 DOI: 10.4103/ijpn.ijpn_92_22
R. Sharma, Ajit Kumar, G. Purohit, S. Goyal
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引用次数: 0
Comparison of efficacy of fascia iliaca compartment block using ropivacaine versus ropivacaine with dexmedetomidine versus ropivacaine with dexamethasone for acute pain relief in patients with femoral fractures: A prospective randomized controlled study 一项前瞻性随机对照研究:罗哌卡因与罗哌卡因联合右美托咪定、罗哌卡因联合地塞米松联合髂筋膜间室阻滞治疗股骨骨折急性疼痛的疗效比较
Pub Date : 2022-09-01 DOI: 10.4103/ijpn.ijpn_32_22
K. Arora, Ritu Pauranik, Minanshu Mittal
Context: Landmark-guided fascia iliaca compartment block (FICB) has been used in operation theater to facilitate patient position before administration of subarachnoid block, but its utilization is yet to be explored in the accident and emergency department for acute pain relief in patients with femoral fractures. Aims: The study aims to compare dexmedetomidine and dexamethasone as adjuvants to ropivacaine for FICB for onset and duration of analgesia. Settings and Designs: This was a prospective randomized controlled study performed in Mahatma Gandhi Memorial Medical College, Indore. Subjects and Methods: Ninety patients with femoral factures were allocated into three groups, and each group received 15 ml of study drug; (i) ropivacaine with dexmedetomidine (RD) group (0.2% ropivacaine with 50 μg dexmedetomidine), (ii) ropivacaine with dexamethasone (RM) group (0.2% ropivacaine with 4 mg dexamethasone), and (iii) ropivacaine alone (RP) group (0.2% ropivacaine). Patients were assessed for onset, duration of analgesia, and need for rescue analgesic. Severity of pain was assessed using Numerical Rating Scale (NRS) score. Statistical Analysis Used: Comparison of means of three groups was done using One-Way ANOVA and pair-wise comparisons using post hoc Tukey's test. Results: The onset of analgesia was earlier in Group RD at 4.38 min followed by Group RM at 4.45 min and Group RP at 7.86 min, whereas the duration of analgesia was longer in Group RD at 725 min followed by Group RM at 594 min and Group RP at 275 min. NRS Score was comparable before application of FICB. After the block, the mean NRS score in Group RD was 3.83, in Group RM was 5.30, and in Group RP was 7.93. Conclusions: FICB is an effective alternative to intravenous opioids and nonsteroidal anti-inflammatory drugs for acute pain relief in patients with femoral fractures, and dexmedetomidine and dexamethasone can be used as adjuvants to ropivacaine as they both enhance quality of block.
背景:Landmark引导髂筋膜间隔阻滞(FICB)已在手术室用于蛛网膜下腔阻滞给药前方便患者定位,但其在急诊科用于股骨骨折患者急性疼痛缓解的应用尚待探索。目的:本研究旨在比较右美托咪定和地塞米松作为罗哌卡因辅助FICB的镇痛起效和持续时间。设置和设计:这是一项在印多尔圣雄甘地纪念医学院进行的前瞻性随机对照研究。受试者和方法:将90例股骨骨折患者分为三组,每组接受15ml研究药物;(i) 罗哌卡因联合右美托咪定(RD)组(0.2%罗哌卡因加50μg右美托咪定),(ii)罗哌卡因+地塞米松(RM)组(0.2%罗哌卡因加4 mg地塞米松),和(iii)单独罗哌卡因(RP)组(0.2%罗哌卡因)。评估患者的起效时间、镇痛持续时间和抢救性镇痛的需要。使用数值评定量表(NRS)评分评估疼痛的严重程度。使用的统计分析:使用单向方差分析对三组的平均值进行比较,并使用事后Tukey检验进行配对比较。结果:RD组在4.38分钟开始镇痛较早,RM组在4.45分钟开始镇痛,RP组在7.86分钟开始镇痛。而RD组在725分钟开始镇痛较长,RM组为594分钟,RP组为275分钟。在应用FICB之前,NRS评分可比。阻断后,RD组的平均NRS得分为3.83,RM组为5.30,RP组为7.93。结论:FICB是静脉注射阿片类和非甾体抗炎药缓解股骨骨折患者急性疼痛的有效替代品,右美托咪定和地塞米松可作为罗哌卡因的佐剂,因为它们都能提高阻滞质量。
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引用次数: 0
Knowledge, awareness, and practices of chronic pain among uttarakhand patients 北阿坎德邦患者慢性疼痛的知识、意识和实践
Pub Date : 2022-09-01 DOI: 10.4103/ijpn.ijpn_79_22
Kirtika Saini, N. Gupta, Ajit Kumar
Background: Chronic pain is a silent pandemic with a prevalence varying from 15% to 30% globally. Yet there is widespread ignorance among health professionals as well as society. We conducted this institution-based study among chronic pain patients with the aim to know their awareness and knowledge about chronic pain and pain physicians. The gist of this study can help us in future to bridge the gap and create mindfulness among the masses regarding chronic pain. Materials and Methods: Two hundred and seventy-three people with chronic pain were questioned about their knowledge and awareness of chronic pain through a questionnaire comprising eight questions. Results: Out of 273 participants, 84.62% took treatment for chronic pain. Yet only 2% consulted pain physicians. 62.64% and 73.63% had no idea about chronic pain being a disease in itself and pain physicians, respectively. All the illiterate participants were unaware of the presence of pain specialists and 89.47% of them were ignorant of the sound effects of physical activities in treating chronic pain conditions. Conclusion: The majority of the participants were not aware that chronic pain can be a disease in itself and that there are pain physicians who specialize in treating this condition. However, most of them had an idea about the beneficial effects of performing daily physical activities. Furthermore, the level of education had an impact with illiterates having the least insight about the participants. These lacunae can be improved by educating people, creating more awareness, and further encouraging pain services.
背景:慢性疼痛是一种无声的流行病,全球患病率从15%到30%不等。然而,在卫生专业人员和社会中普遍存在着无知。我们在慢性疼痛患者中进行了这项基于机构的研究,目的是了解他们对慢性疼痛和疼痛医生的认识和知识。这项研究的要点可以帮助我们在未来弥合这一差距,并在大众中创造关于慢性疼痛的正念。材料和方法:通过一份由8个问题组成的问卷,对273名慢性疼痛患者的慢性疼痛知识和意识进行调查。结果:在273名参与者中,84.62%的人接受了慢性疼痛治疗。然而,只有2%的人咨询了疼痛医生。62.64%和73.63%的人分别不知道慢性疼痛本身是一种疾病,也不知道疼痛医生。所有文盲参与者都不知道疼痛专家的存在,其中89.47%的人不知道体育活动在治疗慢性疼痛方面的良好效果。结论:大多数参与者没有意识到慢性疼痛本身就是一种疾病,而且有专门治疗这种疾病的疼痛医生。然而,他们中的大多数人都知道进行日常体育活动的有益效果。此外,教育水平也有影响,文盲对参与者的了解最少。可以通过教育人们、提高认识和进一步鼓励疼痛服务来改善这些缺陷。
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引用次数: 0
Artificial neural network in clinical pain medicine and research 人工神经网络在临床疼痛医学中的应用与研究
Pub Date : 2022-09-01 DOI: 10.4103/ijpn.ijpn_111_22
Prateek Arora, Samarjit Dey
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引用次数: 0
A rare event of vestibular complication following percutaneous trigeminal radiofrequency ablation 经皮三叉神经射频消融后前庭并发症的罕见事件
Pub Date : 2022-09-01 DOI: 10.4103/ijpn.ijpn_46_21
Sudheer Dara, V. Elumalai, M. Chandra
We report here to draw attention to an uncommon complication that could arise from routinely performed procedure in pain practice such as percutaneous trigeminal radiofrequency ablation (RFA). We report a case of a 53-year-old female who underwent trigeminal nerve RFA for trigeminal neuralgia. RFA after adequate assessment with sensory and motor stimulation is performed as a routine procedure followed by 0.2 ml 1% lignocaine for dense sensory block at the target, following which the patient developed giddiness, nausea, vomiting, and nystagmus. After 2 h of rest and gaze fixation, her symptoms improved, with a decline in the severity of nystagmus. Symptoms gradually resolved over a period of 3 h. Proximity of the membranous part of the auditory tube to the foramen ovale might lead to such mishaps. Direct administration of 1% lignocaine into the middle ear via the auditory tube might be the most likely reason for her condition.
我们在此报告是为了引起人们对一种罕见并发症的注意,这种并发症可能是由疼痛实践中的常规手术引起的,如经皮三叉神经射频消融(RFA)。我们报告一例53岁女性,因三叉神经痛接受三叉神经RFA治疗。在用感觉和运动刺激进行充分评估后,作为常规程序进行RFA,然后用0.2ml 1%利多卡因对目标进行致密感觉阻滞,随后患者出现眩晕、恶心、呕吐和眼球震颤。经过2小时的休息和注视,她的症状有所改善,眼球震颤的严重程度有所下降。症状在3小时内逐渐缓解。耳管膜部靠近卵圆孔可能会导致此类事故。通过耳管直接将1%利多卡因注入中耳可能是她出现这种情况的最可能原因。
{"title":"A rare event of vestibular complication following percutaneous trigeminal radiofrequency ablation","authors":"Sudheer Dara, V. Elumalai, M. Chandra","doi":"10.4103/ijpn.ijpn_46_21","DOIUrl":"https://doi.org/10.4103/ijpn.ijpn_46_21","url":null,"abstract":"We report here to draw attention to an uncommon complication that could arise from routinely performed procedure in pain practice such as percutaneous trigeminal radiofrequency ablation (RFA). We report a case of a 53-year-old female who underwent trigeminal nerve RFA for trigeminal neuralgia. RFA after adequate assessment with sensory and motor stimulation is performed as a routine procedure followed by 0.2 ml 1% lignocaine for dense sensory block at the target, following which the patient developed giddiness, nausea, vomiting, and nystagmus. After 2 h of rest and gaze fixation, her symptoms improved, with a decline in the severity of nystagmus. Symptoms gradually resolved over a period of 3 h. Proximity of the membranous part of the auditory tube to the foramen ovale might lead to such mishaps. Direct administration of 1% lignocaine into the middle ear via the auditory tube might be the most likely reason for her condition.","PeriodicalId":32328,"journal":{"name":"Indian Journal of Pain","volume":"36 1","pages":"156 - 158"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47886319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Indian Journal of Pain
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