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A study to assess meibomian gland morphology using meibography in posterior blepharitis patients and normal population: A hospital-based observational study 一项以医院为基础的观察性研究:后睑炎患者和正常人群中睑板腺形态学的研究
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_135_21
RV Reshmi Nair, Shamin Jacob, K. Praveena, NV Latha, M. Vishnupriya
Introduction: Noncontact infrared meibography (NIM) is a technique for quantitative assessment of meibomian gland (MG) dysfunction by providing images of the morphology of MGs. Aim: The aim of this study is to assess MG morphology using NIM (with meiboscore values) in posterior blepharitis patients and the normal population and to assess the lid margin abnormality score (LMAS), lid margin expression score, tear breakup time (TBUT), and Schirmer test values in posterior blepharitis. Methods: This was a hospital-based study on 100 consecutive patients attending the outpatient department of ophthalmology of the study institute, from June 2019 to May 2020 after getting ethical clearance. The study included 75 patients with symptoms and signs of posterior blepharitis and 25 normal patients with no evidence of posterior blepharitis. All patients were examined using slit lamp biomicroscopy for signs of posterior blepharitis and TBUT, superficial punctate keratopathy, Schirmer 1 test, and LMAS. NIM was performed for both upper and lower eyelids and was documented using the meiboscore system. Results: The meibography gland dropout was significantly higher in posterior blepharitis patients (P < 0.01) compared to normal patients. The normal patients had normal meibography in 32% and total meiboscore of Grade 1 in 56%. The LMAS was significantly higher in posterior blepharitis patients. Superficial punctate keratitis was not significantly higher in posterior blepharitis patients. The lid margin expression score was significantly higher in posterior blepharitis (P < 0.01). TBUT was significantly shorter in posterior blepharitis people (P < 0.01). The Schirmer test showed an adequate tear secretion in both groups of patients. Conclusion: NIM system can be performed easily, quickly, noninvasively and was a patient-friendly method to obtain information about the MG morphology. In our study, the majority of patients with posterior blepharitis showed significant gland dropout as viewed on NIM, compared to the normal cases studied.
引言:非接触红外meibography(NIM)是一种通过提供睑板腺(MG)形态学图像来定量评估MG功能障碍的技术。目的:本研究的目的是使用NIM(具有meiboscore值)评估后睑缘炎患者和正常人群的MG形态,并评估后睑袋炎的盖缘异常评分(LMAS)、盖缘表达评分、撕裂时间(TBUT)和Schirmer试验值。方法:这是一项基于医院的研究,对2019年6月至2020年5月在获得伦理许可后连续100名在研究所眼科门诊就诊的患者进行研究。该研究包括75名有后睑缘炎症状和体征的患者和25名没有后睑缘炎症迹象的正常患者。所有患者均使用裂隙灯生物显微镜检查后睑缘炎和TBUT、浅点状角膜病变、Schirmer 1试验和LMAS的体征。对上眼睑和下眼睑进行NIM,并使用meiboscore系统进行记录。结果:后睑缘炎患者的睑缘腺脱落率明显高于正常人(P<0.01)。正常患者有32%的meibography正常,56%的患者有1级meiboscore。LMAS在后睑缘炎患者中显著增高。浅表点状角膜炎在后睑缘炎患者中并不显著增高。眼睑边缘表达评分在后睑缘炎患者中显著升高(P<0.01)。TBUT在后睑袋炎患者中明显缩短(P<0.01),Schirmer试验显示两组患者都有足够的泪液分泌。结论:NIM系统操作简便、快速、无创,是一种方便患者获取MG形态信息的方法。在我们的研究中,与所研究的正常病例相比,大多数后睑缘炎患者在NIM上表现出显著的腺体脱落。
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引用次数: 0
A study on efficacy of various formulas for intraocular lens power calculation in hyperopic patients at a tertiary care center 三级医疗中心各种人工晶状体度数计算公式在远视患者中的疗效研究
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_169_21
Kunjan Patel, Dipika Patel, Parth Dave
Purpose: Our study was conducted to evaluate and compare the predictive capacity of five intraocular lens (IOL) power calculation formulas (SRK/T, HOFFERQ, HOLLADAY1, HAIGIS, BARRETT UNIVERSAL II) in eyes with axial length (AL) <22 mm. Subjects and Methods: In our study, 100 patients with a preoperative AL of <22 mm were included. All patients underwent uneventful cataract surgery with IOL implantation and postoperative target of refraction were analyzed after 40 days. The mean estimation error and mean absolute error (MAE) were calculated for each formula, and ANOVA test was applied to compare the differences in the MAEs of the formulas. A statistically significant difference was defined as P < 0.05. Results: A statistically significant difference was seen between Barrett Universal II formula in comparison to SRK/T formula. There was no statistically significant difference seen among the absolute error of all the five IOL power calculation formula groups. Conclusions: Among the formulas compared, Barrett Universal II formula is the most accurate in predicting postoperative refractive error in hyperopic patients. Hoffer Q, Haigis, and Holladay 1 formula give better results than the commonly used SRK/T formula.
目的:我们的研究旨在评估和比较五种人工晶状体度数计算公式(SRK/T、HOFFERQ、HOLLAY1、HAIGIS、BARRETT UNIVERSAL II)对眼轴长度(AL)<22mm的预测能力。受试者和方法:在我们的研究中,包括100名术前AL<22mm的患者。所有患者均接受了平静的白内障人工晶状体植入术,并在40天后对术后屈光目标进行了分析。计算每个公式的平均估计误差和平均绝对误差(MAE),并应用ANOVA检验来比较公式的MAE差异。差异有统计学意义(P<0.05)。结果:与SRK/T配方奶粉相比,Barrett Universal II配方奶粉在统计学上存在显著差异。所有五个IOL屈光力计算公式组的绝对误差之间没有统计学上的显著差异。结论:在比较的公式中,Barrett Universal II公式在预测远视患者术后屈光不正方面最准确。Hoffer Q、Haigis和Holladay 1公式比常用的SRK/T公式给出了更好的结果。
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引用次数: 0
Impact of COVID-19 on ophthalmology residency training - can it be swept under the rug? COVID-19对眼科住院医师培训的影响——它能被掩盖吗?
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_1_23
Anubhav Singh, Dipika Sainath, Anujeet Paul
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引用次数: 0
Changing trends in the use of anti-vascular endothelial growth factor (anti-VEGF) biosimilars: Insights from the Vitreoretinal Society of India Biosimilars of Anti-VEGF Survey 抗血管内皮生长因子(anti-VEGF)生物类似药使用的变化趋势:来自印度玻璃体视网膜学会抗vegf生物类似药调查的见解
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_102_22
Dhanya Radhamani Sasidharan
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引用次数: 1
“Ousted little elf”—Secondary glaucoma in Weill-Marchesani syndrome “被驱逐的小精灵”- weil - marchesani综合征继发性青光眼
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_65_23
Devi Karthya
Ocular features of Weill-Marchesani syndrome include ectopia lentis, myopia, and pupillary block glaucoma. The purpose of this case report is to describe a case of secondary glaucoma in an 18-year-old female with suspected Weill-Marchesani syndrome.
Weill-Marchesani综合征的眼部特征包括晶状体异位、近视和瞳孔闭塞性青光眼。本病例报告的目的是描述一例继发性青光眼在一个18岁的女性怀疑Weill-Marchesani综合征。
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引用次数: 0
Clinical features, diagnosis, and treatment outcome of Rhino-orbito-cerebral mucormycosis: A 2-year experience at a tertiary care center 犀牛眶脑毛霉菌病的临床特征、诊断和治疗结果:在三级护理中心的2年经验
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_137_21
A. Vivekanand, S. Nannaware
Context: The incidence of the fungal disease, mucormycosis, is showing a steady increase among the Indian population in recent past years. Considered as a form of acute invasive fungal rhinosinusitis, the disease is characterized by high morbidity and mortality rates. Aims: The aim of this study was to study the clinical presentations, species distribution, and treatment outcomes in patients of rhinomucormycosis. Settings and Design: This was a tertiary care hospital-based case series. Subjects and Methods: The study was carried out between June 2018 and February 2020. All laboratory-confirmed cases of rhinomucormycosis were included in the study population. Results: Sixteen cases of histopathologically and microbiologically confirmed cases of rhinomucormycosis were included in the study. The study population included ten females and six males. Diabetes mellitus was found to be the most common comorbid condition in the study group (81.25%). Among the study group, swelling of cheek and thick blood-stained discharge were the most common presenting symptoms (9 cases out of 16). The most common clinical type was rhino-orbital mucormycosis. Rhizopus was the most common species encountered (87.5%). In spite of utmost care, treatment outcome was not favorable in most of the cases. Conclusion: An early diagnosis of mucormycosis in the background of immunocompromised status can help in initiating appropriate treatment, thereby reducing the morbidity and mortality associated with this disease condition.
背景:近年来,印度人口中毛霉菌病的发病率稳步上升。该病被认为是急性侵袭性真菌性鼻窦炎的一种,其特点是发病率和死亡率高。目的:本研究的目的是研究鼻毛霉菌病患者的临床表现、物种分布和治疗结果。设置和设计:这是一个基于三级护理医院的案例系列。受试者和方法:该研究于2018年6月至2020年2月进行。所有实验室确诊的鼻毛霉菌病病例均包括在研究人群中。结果:本研究包括16例经组织病理学和微生物学证实的鼻毛霉菌病病例。研究人群包括10名女性和6名男性。糖尿病是研究组中最常见的合并症(81.25%)。在研究组中,脸颊肿胀和浓稠的血染分泌物是最常见的症状(16例中有9例)。最常见的临床类型是鼻眼眶毛霉菌病。根霉是最常见的菌种(87.5%)。尽管尽了最大的努力,但大多数病例的治疗结果并不理想。结论:在免疫功能低下的背景下早期诊断毛霉菌病有助于启动适当的治疗,从而降低与该疾病相关的发病率和死亡率。
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引用次数: 0
Bilateral proptosis in Marshall-Smith syndrome Marshall-Smith综合征的双侧眼球突出
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_123_21
D. Das, Divya Chauhan, Sahil Agrawal, M. Bajaj
Marshall-Smith syndrome (MSS) is an extremely rare developmental disorder characterized by accelerated skeletal maturation, failure to thrive, dysmorphic facies, respiratory difficulties, and neurological abnormalities. Herein, the authors report bilateral proptosis in a 10-year-old child with MSS. At present, there are limited reports on ophthalmologic considerations in MSS; therefore, this article subserves to broaden the clinical spectrum seen in this syndrome.
Marshall-Smith综合征(MSS)是一种极其罕见的发育障碍,其特征是骨骼加速成熟、发育迟缓、畸形相、呼吸困难和神经异常。在此,作者报告了一名患有MSS的10岁儿童的双侧眼球突出。目前,关于MSS中眼科考虑因素的报道有限;因此,本文有助于拓宽该综合征的临床范围。
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引用次数: 0
Keratoprosthesis
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_3_23
AH Arya, D. Jacob
Keratoprosthesis (Kpro) is considered as the last resort for bilateral endstage corneal blindness. Commonly performed Kpros are Boston Type 1 and 2 Kpros, Modified Osteoodonto Kpro, OsteoKpro, and Pintucci Kpro. These procedures require an exclusive setup, longterm follow-up, and postKpro care. There is always a significant long-term risk of complications of infection or extrusion of the device with these procedures as the keratoprosthesis is a foreign body. Most common complications of Kpro procedure are postoperative glaucoma, retroprosthetic membrane, sterile melts, and endophthalmitis.
角膜假体(Kpro)被认为是治疗双侧终末期角膜失明的最后手段。常用的Kpros是Boston Type 1和2 Kpros, Modified Osteoodonto Kpro, OsteoKpro和Pintucci Kpro。这些手术需要专门的设置、长期随访和术后护理。由于角膜假体是异物,这些手术总是存在感染或设备挤压并发症的重大长期风险。Kpro手术最常见的并发症是术后青光眼、假体后膜、无菌熔体和眼内炎。
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引用次数: 0
Management of ocular surface irregularity with scleral contact lenses: Experience from a tertiary eye care center 巩膜接触镜治疗眼表不规则:三级眼科护理中心的经验
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_72_21
A. Jabbar
Purpose: This review focuses on the optical and therapeutic benefits which can be offered to patients by evaluating them for scleral contact lenses, and the purpose of this study is to select the indications and to find out how efficient the scleral contact lenses are in treating severe corneal ectasias, highly irregular astigmatism and ocular surface diseases (OSDs) which are otherwise difficult to manage. This retrospective observational case series study analyzed a database of 50 consecutive patients (69 eyes) fitted with scleral lenses between January 2017 and December 2019. All consecutive eyes which were given scleral contact lens trials were analyzed. Results: The study population included 34 males and 16 females, with ages ranging from 7 to 80 years. The mean follow-up was 12 months. The mean wearing time in the successful wearers group was 12.2 hours per day (range 10–16). Vision improvement (optical purpose) was the reason for the fitting in 48 eyes (67.60%), and OSD management (therapeutic purpose) in 23 eyes (32.39%). In the former group, 56.52% (n = 26) had keratoconus, and 43.48% (n = 20) had irregular astigmatism other than keratoconus. Among the OSD patients, 56.52% had Steven Johnson syndrome (SJS) sequelae, 17.39% had severe dry eye, 17.39% had chemical injury sequelae, and 8.69% had xeroderma. Keratoconus patients achieved visual acuity of more than 20/32 in 92.3% of eyes. Among the SJS patients, 69.23% had more than 20/40 (38.46% had 20/20). Conclusion: There is compelling evidence in the literature that scleral contact lenses can provide good results for the challenging patient groups described in this review. We have experienced that scleral contact lenses expand the management of corneal pathologies, especially in OSDs.
目的:这篇综述的重点是通过评估巩膜接触镜对患者的光学和治疗益处,本研究的目的是选择适应症,并了解巩膜接触镜在治疗严重角膜扩张症方面的有效性,高度不规则散光和眼表疾病(OSDs),否则难以控制。这项回顾性观察性病例系列研究分析了2017年1月至2019年12月期间连续50名佩戴巩膜镜片的患者(69眼)的数据库。对所有接受巩膜接触镜试验的连续眼睛进行分析。结果:研究人群包括34名男性和16名女性,年龄从7岁到80岁不等。平均随访12个月。成功佩戴者组的平均佩戴时间为每天12.2小时(范围10-16)。视力改善(光学目的)是48眼(67.60%)适合的原因,OSD管理(治疗目的)是23眼(32.39%)适合的理由。在前一组中,56.52%(n=26)患有圆锥角膜,43.48%(n=20)患有除圆锥角膜以外的不规则散光。OSD患者中,56.52%的患者有Steven Johnson综合征(SJS)后遗症,17.39%的患者有严重干眼,17.39%有化学损伤后遗症,8.69%有干皮病。92.3%的患者的视力达到20/32以上。在SJS患者中,69.23%的患者超过20/40(38.46%的患者达到20/20)。结论:文献中有令人信服的证据表明,巩膜隐形眼镜可以为本综述中描述的具有挑战性的患者群体提供良好的效果。我们已经体验到巩膜隐形眼镜扩大了角膜病变的治疗范围,尤其是在OSD中。
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引用次数: 0
Amblyopia: Effectiveness of visual screening for early detection in a comparative study between urban and rural school children 弱视:城乡学童视力筛查早期发现的有效性比较研究
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_37_21
BV Sneha, P. Kapadia, Shivani Jariwala
Background: Amblyopia an important health problem among young children causing lifelong visual impairment if not treated at correct age. Timely screening of children for amblyopia and its appropriate treatment can prevent the consequences of the problem in their adulthood. Materials and Methods: This study carried out a visual screening of 1234 school children in the age group of 3–12 years of urban and rural schools. All children having vision < 6/6, were called for detailed ophthalmic evaluation at tertiary care Government Hospital. Children who met the inclusion criteria and their best-corrected visual acuity found to be <6/6 on Snellen's chart even after refractive check-up, were assessed for different amblyopia tests to categorize amblyopia into various types and severity. Results: The prevalence of amblyopia in study group was 2.41% (8) in rural and 1.43% (13) in urban schools of 78 children from urban and 37 children from rural referred for detailed Ophthalmic evaluation which includes dropout rate of 24.35% and 35.13% from urban and rural, respectively. The prevalence of isoametropic amblyopia (38.46%) was maximum in urban whereas in rural it was anisometropic amblyopia (37.5%). Among the strabismic amblyopia, most frequent pattern was exotropia in both the groups, moderate degree amblyopia was more in urban and severe degree in rural. Amblyopia was bilateral in most of urban (61.53%) whereas unilateral in most of rural (75%) children. Hypermetropic refractive error was more prevalent in both urban and rural. Conclusion: The prevalence of amblyopia was found more in rural children. The study highlighted differences in the severity of amblyopia, its types, and common refractive errors in both the groups. On the whole, there was no statistically significant difference in all parameters among both the groups.
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引用次数: 0
期刊
Kerala Journal of Ophthalmology
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