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Delayed presentation, deeper peril: Ophthalmia nodosa 迟发,更严重的危险:结节性眼科
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_176_21
S. Reddy, Agrima Bhatia, Priyesh Kumar, S. Mohan, HemantSingh Trehan
Ophthalmia nodosa is an ocular inflammatory reaction due to the lodging of foreign bodies such as caterpillar spines and tarantula hair. Initial manifestations include edematous eyelids, conjunctival injection associated with multiple corneal abrasions. Subsequent migration of insect hair anteriorly to posteriorly may result in nodular conjunctivitis, iridocyclitis, vitritis, and even panophthalmitis. We report a case of ophthalmia nodosa in a military recruit who presented to us 1 week after the injury. By the time, he presented the setae were deep-seated leading to significant ocular manifestations and was initially managed conservatively before actively intervening to remove the setae.
结节性眼病是一种眼部炎症反应,由毛毛虫棘和狼蛛毛等异物引起。最初的表现包括眼睑水肿,结膜注射伴有多处角膜擦伤。随后昆虫毛发从前向后迁移可能导致结节性结膜炎、虹膜睫状体炎、镜质炎,甚至全眼炎。我们报告了一名新兵在受伤一周后出现结节性眼炎的病例。到那时,他发现刚毛是深层的,导致了显著的眼部表现,在积极干预切除刚毛之前,最初进行了保守治疗。
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引用次数: 0
An unusual presentation of aneurysmal bone cyst of the maxillary sinus in a child: A rare case report 儿童上颌窦动脉瘤样骨囊肿的罕见表现:一个罕见的病例报告
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_173_21
Suchismita Mishra, A. Das, Chinthala Navyasree
Aneurysmal bone cyst(ABC) is a rare vascular tumor arising usually from long bone and vertebrae,very rarely involves the skull and facial bone. Here, we present a case of a 9-year-old child presented with progressive proptosis and strabismus of the left eye associated with nasal obstruction and epistaxis. Computed tomography was done which gave us an insight into the possibilities of ABC, giant cell tumor, adenomatoid odontogenic tumor, etc., Biopsy was taken for histopathological confirmation. Usually, ABC of the maxillary sinus presents with pain, cheek swelling, and nasal obstruction. Our patient presented with ocular findings which are rare among maxillary bone ABCs.
动脉瘤性骨囊肿(ABC)是一种罕见的血管性肿瘤,通常发生在长骨和椎骨,很少累及颅骨和面骨。在这里,我们提出一个9岁儿童的情况下,表现为进行性突出和斜视的左眼,并伴有鼻塞和鼻出血。行计算机断层扫描,了解ABC、巨细胞瘤、腺瘤样牙源性肿瘤等可能性,行活检组织病理证实。通常,上颌窦ABC表现为疼痛、脸颊肿胀和鼻塞。本例患者的眼部表现在上颌骨abc中是罕见的。
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引用次数: 0
Macular morphological changes in retinal vein occlusion with macular involvement and their association with macular ischemia 黄斑受累视网膜静脉闭塞的黄斑形态改变及其与黄斑缺血的关系
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_201_21
Renuka Rawat, Charudatt Chalisgaonkar, D. Tripathi, S. Jain
The aim is to study the association between macular morphological changes and macular ischemia in retinal vein occlusion (RVO) involving macula by spectral domain-optical coherence tomography (SD-OCT). Observational cross-sectional study. The study included a total of 31 eyes of 30 RVO patients involving macula divided into two groups on the basis of fundus fluorescein angiography: Group A (RVO with macular ischemia) and Group B (RVO without macular ischemia). In each patient, macular cube and horizontal HD raster scans of the macula were performed to evaluate quantitative (central foveal thickness [CFT]) and qualitative (loss of inner retinal layers, loss of foveal inner segment/outer segment [IS/OS] junction, and prominent middle-limiting membrane [p-MLM] sign) macular morphological changes, respectively. The continuous and categorical data were analyzed using unpaired t-test and Fisher’s exact test, respectively, with GraphPad Prism 9 software. The mean CFT was thinner in Group A (432.71 ± 172.30 µm) as compared to Group B (564.57 ± 151.16 µm) and the difference between the two groups was statistically significant (P < 0.05). In this study, we found that the loss of inner retinal layer and loss of foveal IS/OS junction were more commonly associated with the macular ischemia group and this difference was statistically significant P = 0.0245 and 0.0292, respectively. We did not find any significant relationship between p-MLM sign with macular ischemia. SD-OCT parameters such as CFT, loss of inner retinal layer, and loss of foveal IS/OS junction were observed to predict macular ischemia to some extent.
目的是通过光谱域光学相干断层扫描(SD-OCT)研究黄斑视网膜静脉闭塞(RVO)累及黄斑的黄斑局部缺血与黄斑形态变化的关系。观察性横断面研究。本研究共纳入30例涉及黄斑的RVO患者31眼,根据眼底荧光素血管造影分为两组:a组(伴有黄斑缺血的RVO)和B组(无黄斑缺血的RVO)。对每位患者进行黄斑立方体和水平高清光栅扫描,分别定量(中央中央凹厚度[CFT])和定性(视网膜内层缺失、中央凹内段/外段[IS/OS]连接处缺失和明显的中限膜[p-MLM]征象)黄斑形态改变。使用GraphPad Prism 9软件,对连续数据和分类数据分别采用非配对t检验和Fisher精确检验进行分析。A组平均CFT(432.71±172.30µm)较B组(564.57±151.16µm)变薄,差异有统计学意义(P < 0.05)。本研究中,我们发现黄斑缺血组视网膜内层缺失和中央凹IS/OS连接处缺失更为常见,差异有统计学意义P = 0.0245和0.0292。我们没有发现p-MLM与黄斑缺血有明显的关系。观察SD-OCT参数如CFT、视网膜内层丢失、中央凹IS/OS连接丢失在一定程度上预测黄斑缺血。
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引用次数: 0
Evaluation of tacrolimus and cyclosporine in the treatment of vernal keratoconjunctivitis in children 他克莫司与环孢素治疗儿童春性角膜结膜炎的疗效评价
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_46_22
A. Suresha, G. Shashidhar, H. Prabhudeva
To compare the efficacy and safety of 0.03% tacrolimus eye ointment with 2% cyclosporine eye drops in the treatment of vernal keratoconjunctivitis. Comparative, Hospital-based, Prospective, Randomized, Clinical study. About 56 children diagnosed with Vernal keratoconjunctivitis (VKC) were enrolled in the study. All the subjects underwent a comprehensive ophthalmic evaluation. Total subjective symptom scoring (TSSS) and Total objective sign scoring (TOSS) were done for each patient based on their history and clinical examination. They were divided into two groups. One group was treated with 0.03% tacrolimus ointment bd and the other with 2% cyclosporine eye drops tid. Both groups were also put on carboxymethylcellulose eye drops four times a day. Steroids were never used during the study. The patients were followed up at intervals of two weeks, four weeks, and eight weeks. At each follow-up, the TSSS and TOSS were done for each patient. Patients were also questioned about any adverse effects encountered by them during the treatment. A comparison was done between both groups based on the above scoring. There was progressive reduction which was statistically significant (P < 0.05) in the TSSS and TOSS in both the groups throughout treatment. Reduction in TSSS The only adverse effect reported by a few patients was a burning sensation that was not severe enough to discontinue treatment. Both tacrolimus 0.03% eye ointment and cyclosporine 2% eye drops are effective in the treatment of VKC without any significant severe side effects. Tacrolimus eye ointment was more effective than cyclosporine drops.
比较0.03%他克莫司眼膏与2%环孢素滴眼液治疗春性角膜结膜炎的疗效和安全性。比较的、基于医院的、前瞻性的、随机的临床研究。大约56名被诊断为春性角膜结膜炎(VKC)的儿童参加了这项研究。所有受试者都进行了全面的眼科评估。根据患者的病史和临床检查对患者进行总主观症状评分(TSSS)和总客观体征评分(TOSS)。他们被分成两组。一组给予0.03%他克莫司软膏bd,另一组给予2%环孢素滴眼液tid。两组患者还每天使用四次羧甲基纤维素滴眼液。研究中从未使用过类固醇。随访时间分别为2周、4周和8周。在每次随访中,对每位患者进行TSSS和TOSS。患者还被问及在治疗过程中遇到的任何不良反应。根据上述评分对两组进行比较。两组患者治疗过程中TSSS、TOSS均有进行性降低,差异有统计学意义(P < 0.05)。少数患者报告的唯一不良反应是烧灼感,严重程度不足以停止治疗。0.03%他克莫司眼膏和2%环孢素滴眼液均可有效治疗VKC,且无明显严重副作用。他克莫司眼膏比环孢素滴眼液更有效。
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引用次数: 0
Ophthalmic prostaglandin analogs revisited - A systematic review of commonly used formulations 眼科前列腺素类似物重访-对常用制剂的系统回顾
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_5_22
K. Feroze
To systematically review the randomized control trials (RCTs) of the various prostaglandin(PG) analogues, comparing the effectiveness in treating glaucomas, safety and adverse effects of the individual agents. Articles were searchedusing the following key words “PG analogues”, “Latanoprost”, “ Bimatoprost”, “Travoprost”, “ Tafluprost”, “Unoprostone”, “ophthalmology”, “randomized controlled trial”, either singly or variably combined. Databases searched included Pubmed, Embase, Cochrane library, and Science direct. The search strategy was to identify randomized control trials (RCTs), either singly or variably combined. 24 Randomised control trials that had evaluated the efficacy and adverse effects of different PG analogue agents were selected and were used in this review Average JADAD value of the researches was found to be 2.83. Bimatoprost was found to be the most effective agent in IOP lowering efficacy but it had the maximal incidence of local adverse effects. Latanoprost, Travoprost and Tafluprost had similar efficacy. Latanoprost had the best tolerability. Unoprostone had weaker antiglaucoma action, compared to the other agents. Bimatoprost is probably one of the best antiglaucoma medications available at present. Its tolerability could be improved by using preservative free formulations. Latanoprost is a well tolerated agent with reasonably good antiglaucoma action.
系统回顾各种前列腺素(PG)类似物的随机对照试验(rct),比较各药物治疗青光眼的有效性、安全性和不良反应。使用以下关键词检索文章:PG类似物、拉坦前列素、比马前列素、曲伏前列素、他氟前列素、Unoprostone、眼科、随机对照试验。检索的数据库包括Pubmed、Embase、Cochrane library和Science direct。检索策略是确定随机对照试验(rct),无论是单一的还是变量组合的。本综述选取了24项随机对照试验,对不同PG类似物的疗效和不良反应进行了评价,这些研究的平均JADAD值为2.83。比马前列素是降压效果最好的药物,但局部不良反应发生率最高。拉坦前列素、曲伏前列素和他氟前列素的疗效相似。拉坦前列素耐受性最好。与其他药物相比,Unoprostone的抗青光眼作用较弱。比马前列素可能是目前最好的抗青光眼药物之一。使用不含防腐剂的配方可提高其耐受性。拉坦前列素是一种耐受性良好的抗青光眼药物。
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引用次数: 0
Awareness in parents of preterm babies screened and counselled for retinopathy of prematurity – A study from rural India 对早产儿视网膜病变进行筛查和咨询的早产儿父母的认识-一项来自印度农村的研究
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_174_21
A. Bappal, Rashmi Jain, R. Shambhu, Keerthan Peralaya, V. Hegde, Chaithanya Singh
Introduction: Retinopathy of prematurity (ROP) is one of the causes for preventable blindness in preterm babies. An important reason for delay in treatment and, hence, blindness is delayed follow-up, attributed to the lack of cognizance regarding ROP among parents. Methodology: This cross-sectional questionnaire study was conducted from September 2018 to January 2020 with an aim to assess knowledge, attitude, and practices about ROP among parents of preterm babies. They all had been counselled during previous screening sessions and the questionnaire was administered during the last follow-up for ROP screening. The questionnaire included basic demographic data and questions to assess knowledge, attitude, and practices about ROP. Association between follow-up pattern with knowledge, attitude, economic status, and educational level were analysed. Results: Questionnaire study was conducted on 30 parents of preterm babies. About 83.3% parents were aware that “ROP” is a blinding disease of preterm babies. Twenty-one parents (70%) did not bring their babies for follow-up as per the schedule mentioned in “ROP follow-up card.” Delay in follow-up ranged from 7 to 160 days (median 30 days). Better economic status had statistically significant influence on prompt follow-up. Conclusion: In spite of counselling, sharing educational pamphlets, and having knowledge about blinding complication of ROP, 70% parents did not bring the babies for follow-up on time. Hence, there is a need to strengthen the ROP counselling program.
引言:早产儿视网膜病变(ROP)是早产儿可预防失明的原因之一。延迟治疗和失明的一个重要原因是延迟随访,这归因于父母对ROP缺乏认识。方法:这项横断面问卷研究于2018年9月至2020年1月进行,旨在评估早产儿父母对ROP的知识、态度和实践。他们都在之前的筛查期间接受了咨询,并在ROP筛查的最后一次随访期间进行了问卷调查。问卷包括基本的人口统计数据和评估ROP知识、态度和实践的问题。分析了随访模式与知识、态度、经济状况和教育水平之间的关系。结果:对30名早产儿父母进行问卷调查。约83.3%的父母知道“ROP”是早产儿的致盲性疾病。21名父母(70%)没有按照“ROP随访卡”中提到的时间表带孩子进行随访。随访延迟时间从7天到160天不等(平均30天)。较好的经济状况对及时跟进有统计学上的显著影响。结论:尽管有咨询、分享教育小册子以及了解ROP致盲并发症,但70%的父母没有及时带孩子进行随访。因此,有必要加强ROP咨询计划。
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引用次数: 0
Case series of carotid cavernous fistula: Clinical and management outcomes 颈动脉海绵状瘘病例系列:临床和治疗结果
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_88_21
Appurv Kachhwaha, L. Mohanty, Sitaram Barath
A carotid-cavernous sinus fistula (CCF) is an abnormal vascular communication between internal carotid artery or external carotid artery and veins within cavernous sinus (CS). CCF commonly present with ophthalmic manifestations due to venous drainage of the orbit from the CS. Here, we present case series of four CCFs; two direct and two indirect and discuss their ophthalmological and neuroradiological features and management outcomes with digital subtraction angiography and endovascular coiling. CCF is a rare clinical presentation and its early diagnosis and treatment prevents life and vision-threatening complications.
颈动脉-海绵窦瘘(CCF)是颈内动脉或颈外动脉与海绵窦内静脉之间的异常血管通讯。CCF通常表现为眼窝静脉引流所致。在这里,我们介绍了四个CCFs的病例系列;两个直接和两个间接,并讨论他们的眼科和神经放射学特征和处理结果与数字减影血管造影和血管内卷曲。CCF是一种罕见的临床表现,它的早期诊断和治疗可以防止危及生命和视力的并发症。
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引用次数: 0
An overview of correlation and regression methods in medical research – An ophthalmologic perspective 医学研究中相关与回归方法综述-眼科学视角
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_32_23
NSreekumaran Nair, S. Ganapathy
Correlation and regression are two commonly used statistical techniques in modelling medical data. It s essential for clinicians to understand the methodology of these techniques in general and their implications in clinical area of expertise. This article provides an overview on correlation and regression methods from an ophthalmologic perspective.
相关性和回归是医学数据建模中常用的两种统计技术。对于临床医生来说,了解这些技术的总体方法及其在临床专业领域的含义是至关重要的。本文从眼科的角度综述了相关和回归方法。
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引用次数: 0
IOL opacification: My perspective 人工晶状体混浊:我的观点
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_94_23
S. Saikumar
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引用次数: 0
The patient is our teacher 病人是我们的老师
Pub Date : 2023-01-01 DOI: 10.4103/kjo.kjo_22_23
Smita Narayanan
Medical education is about the patient in all respects. Sir William Osler emphasized that “the student begins with patient, continues with the patient and ends his study with the patient, using books and lectures as tools, as means to an end.[1]” A student should therefore be with the patient, reading the books about the condition of the patient, coming back to the patient for re-examination, discussing with their teachers the condition and the differential diagnosis of that condition, and then going back again to the patient to elicit further details, all the time communicating appropriately with the patient. Hence, it is the patient all the way who occupies the center stage in medical education. In recent years, more and more instances of case presentations are happening without the patient in the classroom. The pandemic has exacerbated this situation to an extreme level. Most of the postgraduate medical teaching is now scenario-based. A scenario is where an imaginary patient with a name has a few symptoms and signs pre-described. The student presents it as a case without the need for eliciting the signs. This scenario is repeatedly played out in multiple sessions. Such training grooms a set of students who have no skills in eliciting a proper history or conducting a proper examination. Their teachers are unable to interrupt them to demonstrate a sign that the student had failed to elicit or to take a history that was omitted. The students do not perfect the art of correlating the patient’s signs with the symptoms and thereby providing a differential diagnosis. Furthermore, their familiarity with the scenario prevents the development of touch, respect, empathy, and the art of professional communication. The increased availability of online classes has greatly helped the students to be up to date with the current standards of care. It has also facilitated exposure to different standards of teaching. The negative is that everybody is forced to believe what the student has presented. The online classes must be used by the student as a resource for advancing knowledge, but learning to elicit skills is equally important. A squint case presentation is taken as an example. The student should be well versed in eliciting the primary and secondary deviations and various types of cover tests, including those with the use of prisms and in the forced duction tests. These skills should be demonstrable during the case presentation. Then only the discussion assumes significance. The relevance lies in repeatedly coming back to the patient for examination. I am sure that there will be proponents of a skill laboratory, but the patient must occupy center stage. Another important malady in patient education is the “no touch.” The pandemic has increased the propensity of no-touch technique of examining the patients, which was already seeping into the examination culture. This, along with the fear in the minds of the teachers of lesser skills in the students causing
医学教育在各个方面都是关于病人的。威廉·奥斯勒爵士强调说:“学生以病人开始,以病人继续,以病人结束他的学习,把书本和讲座作为达到目的的工具和手段。”[1]“因此,学生应该和病人在一起,阅读有关病人病情的书籍,回到病人身边重新检查,与老师讨论病情和鉴别诊断,然后再次回到病人身边询问进一步的细节,始终与病人进行适当的沟通。因此,在医学教育中,始终是病人占据着中心位置。近年来,越来越多的病例报告发生在病人不在教室的情况下。大流行病使这种情况恶化到极端程度。目前大多数研究生医学教学是基于场景的。场景是一个虚构的病人,有一个名字,有一些预先描述的症状和体征。学生把它作为一个案例来呈现,而不需要引出符号。这个场景在多个会话中反复上演。这种培训培养了一群学生,他们没有技巧来引出适当的历史或进行适当的检查。他们的老师无法打断他们,以证明学生没有引出一个迹象,或采取历史省略。学生们没有完善将病人的体征与症状联系起来从而提供鉴别诊断的技巧。此外,他们对场景的熟悉阻碍了接触、尊重、同理心和专业沟通艺术的发展。在线课程的增加极大地帮助学生跟上了当前的护理标准。它还有助于接触不同的教学标准。消极的一面是,每个人都被迫相信学生所呈现的东西。在线课程必须被学生作为一种获取知识的资源,但学习如何引出技能也同样重要。以一个斜视案例为例。学生应精通引出主要和次要偏差以及各种类型的覆盖试验,包括使用棱镜和强制诱导试验。这些技能应该在案例展示中展示出来。只有这样,讨论才有意义。相关性在于反复回到病人身边进行检查。我相信会有技术实验室的支持者,但病人必须占据中心舞台。病人教育的另一个重要弊病是“不接触”。新冠疫情加剧了已经渗透到检查文化中的“无接触检查”的倾向。这一点,再加上教师担心学生的技能较低会对病人造成伤害,导致学生们只是观察病人。只要看看在日常临床工作中引起角膜感觉的学生的极少数,就足以说明“无接触”技术在多大程度上已经悄悄进入了这个系统。这种医学训练的不足,也就是临床技能的不足,现在有了一个名字——低技能症——由赫伯特·弗雷德创造。他说:“高接触医学是基于精心构建的病史,加上相关的身体检查和对由此获得的信息的批判性评估。然后决定哪些研究是必要的。如果研究被认为是必要的,那么简单的研究就会被优先考虑。相比之下,高科技医疗基本上绕过了病史和体格检查,主要基于患者的主诉,直接进行了一系列检查。”高接触医学最好的例子是Nozik在葡萄膜炎中的“命名和网格”技术[2],该技术使我们能够量身定制调查以达到诊断。相比之下,高科技医学进行了大量的研究,几乎是盲目的。医学技术的进步已经渗透到医学教育的各个方面。从前,医生对通过临床检查确定神经损伤部位的正确性感到非常自豪。现在有太多的成像方式,可以在不进行详细临床检查的情况下提供有关疾病确切性质的信息。然而,通过临床检查技巧正确诊断的快感是无法复制的。在另一个特定于眼科的例子中,视盘的详细检查现在处于次要地位,取而代之的是视网膜神经纤维层的光学相干断层扫描越来越受到依赖。 然而,必须记住的是,就像在病人身上引出一个信号需要练习一样,解释一份报告是一件复杂的事情,需要一个人在大量可能的错误中转换,这些错误可能与病人有关,也可能与技术人员有关,也可能与机器有关。因此,对报告的不恰当解释可能导致精神痛苦和开支增加,有时还会导致医疗诉讼。让我们以进行阴道镜检查为例。这项技能既是一门艺术,也是一门科学。艺术在于病人的沟通和让病人在手术过程中感到舒适,而科学在于手术、技术和过程的正确设置。例如,在获得房间的正确照明和正确的狭缝光束尺寸以及光束不穿过瞳孔区域之后,如果学生确定了一个开放的角度,那么学生也有必要详细检查角度以了解存在某种条件,例如角度收缩。如果不这样做,患者将被标记为原发性开角型青光眼,特别是如果其他创伤迹象被遗漏或不存在。这样的技能可以通过对包括正常人在内的患者和患者的双眼按照特定的顺序进行反复检查来学习,其中包括两种类型的镜面角镜检查、操作角镜检查和使用角膜角囊进行压痕角镜检查,然后详细检查角度。有许多因素使病人脱离了医学教学的中心舞台。首先,由于治疗医生的职责越来越多,时间不够用。这些职责除了临床职责外,还包括行政和研究职责。相当多的病人并不仅仅因为症状而去看医生。他们需要医生的同情、安慰和身体上的技能表达。如果病人觉得医生/眼科医生花更多的时间在解释结果或在电脑上填写电子病历上,而不是花时间在检查、[3]教育或安抚他们上,那么他们就会记住这种忽视,并会寻找其他途径。教师应该走出自己的舒适区,回到查房和课堂教学的实践中,展示患者沟通和患者疾病教育的重要性,并在患者负荷、时间短缺和患者成本最小化之间取得平衡,同时要求进行相关调查,同时平衡医疗过失诉讼的趋势。病人负荷较小的机构可以利用技能实验室设施,而病人周转良好的机构可以利用病人的金矿进行学生的继续教育。必须在传统教学方法和技术进步之间取得平衡。[4]我们应该阻止这种“不接触”、神经欠发达和病人沟通不畅的现象。
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引用次数: 0
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Kerala Journal of Ophthalmology
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