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From Bytes to Best Practices: Tracing ChatGPT-3.5's Evolution and Alignment With the National Comprehensive Cancer Network® Guidelines in Pancreatic Adenocarcinoma Management. 从字节到最佳实践:追溯 ChatGPT-3.5 的发展历程以及与《美国国家综合癌症网络® 胰腺腺癌管理指南》(National Comprehensive Cancer Network® Guidelines in Pancreatic Adenocarcinoma Management)的一致性。
Pub Date : 2024-04-26 DOI: 10.1177/00031348241248801
Tamir E Bresler, Shivam Pandya, Ryan Meyer, Zin Htway, Manabu Fujita
INTRODUCTIONArtificial intelligence continues to play an increasingly important role in modern health care. ChatGPT-3.5 (OpenAI, San Francisco, CA) has gained attention for its potential impact in this domain.OBJECTIVETo explore the role of ChatGPT-3.5 in guiding clinical decision-making specifically in the context of pancreatic adenocarcinoma and to assess its growth over a period of time.PARTICIPANTSWe reviewed the National Comprehensive Cancer Network® (NCCN) Clinical Practice Guidelines for the Management of Pancreatic Adenocarcinoma and formulated a complex clinical question for each decision-making page. ChatGPT-3.5 was queried in a reproducible fashion. We scored answers on the following Likert scale: 5) Correct; 4) Correct, with missing information requiring clarification; 3) Correct, but unable to complete answer; 2) Partially incorrect; 1) Absolutely incorrect. We repeated this protocol at 3-months. Score frequencies were compared, and subgroup analysis was conducted on Correctness (defined as scores 1-2 vs 3-5) and Accuracy (scores 1-3 vs 4-5).RESULTSIn total, 50-pages of the NCCN Guidelines® were analyzed, generating 50 complex clinical questions. On subgroup analysis, the percentage of Acceptable answers improved from 60% to 76%. The score improvement was statistically significant (Mann-Whitney U-test; Mean Rank = 44.52 vs 56.48, P = .027).CONCLUSIONChatGPT-3.5 represents an interesting but limited tool for assistance in clinical decision-making. We demonstrate that the platform evolved, and its responses to our standardized questions improved over a relatively short period (3-months). Future research is needed to determine the validity of this tool for this clinical application.
引言人工智能在现代医疗保健领域发挥着越来越重要的作用。目标探索 ChatGPT-3.5 在指导临床决策(尤其是胰腺腺癌)方面的作用,并评估其在一段时间内的增长情况。参与者我们查阅了美国国立综合癌症网络®(NCCN)的《胰腺腺癌管理临床实践指南》,并为每个决策页面制定了一个复杂的临床问题。我们以可重复的方式查询了 ChatGPT-3.5。我们按以下李克特量表对答案进行评分:5)正确;4)正确,但缺少需要澄清的信息;3)正确,但无法完整回答;2)部分错误;1)完全错误。我们在 3 个月后重复了这一方案。我们比较了得分频率,并对正确率(定义为 1-2 分与 3-5 分)和准确率(1-3 分与 4-5 分)进行了亚组分析。结果共分析了 50 页 NCCN Guidelines®,产生了 50 个复杂的临床问题。通过分组分析,可接受答案的百分比从 60% 提高到 76%。得分的提高具有统计学意义(Mann-Whitney U 检验;平均排名 = 44.52 vs 56.48,P = .027)。结论ChatGPT-3.5 是一个有趣但有限的临床决策辅助工具。我们证明,该平台在相对较短的时间内(3 个月)得到了发展,对标准化问题的回答也有所改进。未来的研究需要确定该工具在临床应用中的有效性。
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引用次数: 0
Bile Duct Injuries During Urgent Cholecystectomy at a Safety Net Teaching Hospital: Attending Experience and Time of Day May Matter. 安全网教学医院急诊胆囊切除术中的胆管损伤:主治医生的经验和手术时间可能很重要
Pub Date : 2024-04-26 DOI: 10.1177/00031348241248805
Chaiss Ugarte, Shannon Zielsdorf, Ramsey Ugarte, Odeya Kagan, Ryan Murphy, Matthew J Martin, Kenji Inaba, M. Schellenberg
Background: Bile duct injury (BDI) is one of the most severe complications during cholecystectomy. Early identification of risk factors for BDI may permit risk reduction strategies and inform patient consent.Objective: This study aimed to define patient, provider, and systemic factors associated with BDI; BDI incidence; and short-term outcomes of BDI after urgent cholecystectomy.Methods: Patients who underwent urgent cholecystectomy for acute cholecystitis were retrospectively screened (2020-2022). All patients who sustained BDI were included without exclusions. Demographics, clinical data, and outcomes were collected and compared with descriptive statistics.Results: During the study period, BDI occurred in 4 (0.5%) of 728 patients who underwent urgent cholecystectomy for acute cholecystitis. Most BDI cases (75%) took place overnight or during the weekend. The attending surgeon was almost exclusively (75%) in their first year of practice. BDI was recognized during index operation in 2 cases (50%). Hepatobiliary surgery performed the bile duct repair in all 4 cases. Two complications occurred (50%). All patients were followed by hepatobiliary surgery in the outpatient setting and returned to their baseline level of function within 2 months of hospital discharge.Conclusion: Most BDI occurred in procedures attended by first-year faculty during after hours cholecystectomies, suggesting a role for increased proctorship in early career attendings in addition to in-hours cholecystectomy for acute cholecystitis. The timely return to baseline function experienced by these patients emphasizes the favorable outcomes associated with early recognition of BDI and involvement of hepatobiliary surgery. Further examination with multicenter evaluation would be beneficial to validate these study findings.
背景:胆管损伤(BDI)是胆囊切除术中最严重的并发症之一。及早识别 BDI 的风险因素可以采取降低风险的策略,并为患者的同意提供依据:本研究旨在确定与 BDI 相关的患者、提供者和系统因素;BDI 发生率;以及紧急胆囊切除术后 BDI 的短期结果:对因急性胆囊炎接受紧急胆囊切除术的患者进行回顾性筛选(2020-2022 年)。所有持续 BDI 的患者均被纳入,无一例外。收集人口统计学、临床数据和结果,并通过描述性统计进行比较:在研究期间,728 名因急性胆囊炎接受紧急胆囊切除术的患者中有 4 例(0.5%)发生了 BDI。大多数 BDI 病例(75%)发生在夜间或周末。主治医生几乎全部(75%)都是第一年执业。有 2 例病例(50%)的 BDI 是在索引手术中发现的。肝胆外科为所有 4 例患者进行了胆管修复手术。发生了两例并发症(50%)。所有患者都在门诊接受了肝胆外科随访,并在出院后两个月内恢复到了基本功能水平:结论:大多数 BDI 发生在由一年级教师在下班后进行的胆囊切除术中,这表明除了在下班后对急性胆囊炎进行胆囊切除术外,还需要增加职业生涯早期主治医师的监查。这些患者及时恢复了基线功能,强调了早期识别 BDI 和肝胆外科参与治疗的良好效果。进一步的多中心评估将有助于验证这些研究结果。
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引用次数: 0
Contemporary Outcomes and Patterns of Injury Associated With Parachuting Accidents. 与跳伞事故有关的当代伤害结果和模式。
Pub Date : 2024-04-25 DOI: 10.1177/00031348241248809
Ramsey S Elsayed, Avian Pham, Nikilish Chitibomma, Macey Yates, Kaylene Barrera, Marvin J Atchison, Titio F Gorski
BACKGROUNDSkydiving is an increasingly popular recreational activity in the United States and worldwide. While it is considered a high-risk sport, the United States Parachute Association reported a fatality of .28 per 100 000 jumps in 2022. Although mortality rates are low, the true rate of survivable injuries is unknown. Injuries requiring hospitalization are not uncommon and may be underreported in the literature. Anticipating these injuries and analyzing short-term outcomes following parachuting accidents would be useful for the development of mitigation strategies and to increase the safety of jumpers.METHODSA retrospective cohort review of 126 consecutive patients presenting to a Level II Trauma Center after skydiving accidents between 2016 and 2023. Patient baseline characteristics, patterns of injury, surgical procedures, and in-hospital outcomes were reviewed.RESULTSA total of 126 patients were included. One hundred and seventeen patients (93%) presented immediately following the accident, 65 (51.6%) were trauma activations, and 14 (11.1%) patients experienced loss of consciousness. Fractures of the lower extremity occurred in 57 (45%), fractures of the spine 48 (38%), upper extremity 13 (10%), pelvis 11 (9%). Of the spinal injuries, 10 injuries occurred in the cervical spine, 16 thoracic, 22 lumbar, 5 sacral, and 3 coccygeal spine. Eleven patients (9%) suffered multilevel spine injuries. Mean injury severity score was 7 (range 0-75). A third of patients required at least 1 surgical procedure (n = 43, 34%). Median length stay was 2 days (IQR 1, 5). Of patients who survived to our trauma center, there were two mortalities, both due to catastrophic intracranial hemorrhage.DISCUSSIONAlthough the 30-day mortality rate for patient who presented to our trauma center is low, it can bear significant risks including major injury. The most common injuries were lower extremity and spinal in origin with a third of patients overall requiring at least one operation.
背景在美国和全世界,跳伞是一项越来越受欢迎的娱乐活动。虽然它被认为是一项高风险运动,但据美国降落伞协会报告,2022 年每 10 万次跳伞中死亡人数为 0.28 人。虽然死亡率很低,但可存活的真实受伤率却不得而知。需要住院治疗的伤害事故并不少见,文献中也可能少报。预测这些损伤并分析跳伞事故后的短期结果将有助于制定缓解策略和提高跳伞者的安全。方法对 2016 年至 2023 年间跳伞事故后连续 126 名患者到二级创伤中心就诊的情况进行回顾性队列研究。结果共纳入 126 名患者。117名患者(93%)在事故发生后立即就诊,65名患者(51.6%)为外伤激活,14名患者(11.1%)意识丧失。有 57 人(45%)发生下肢骨折,48 人(38%)发生脊柱骨折,13 人(10%)发生上肢骨折,11 人(9%)发生骨盆骨折。在脊柱损伤中,颈椎损伤 10 例,胸椎损伤 16 例,腰椎损伤 22 例,骶椎损伤 5 例,尾椎损伤 3 例。有 11 名患者(9%)的脊柱受到多层次损伤。受伤严重程度平均分为 7 分(0-75 分不等)。三分之一的患者至少需要进行一次手术(43 人,34%)。住院时间中位数为 2 天(IQR 1,5)。在我们的创伤中心存活下来的患者中,有两人死亡,都是由于严重的颅内出血。最常见的损伤是下肢和脊柱损伤,三分之一的患者至少需要进行一次手术。
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引用次数: 0
The USCENTCOM Walking Blood Bank Performance Benchmark and Anticipated Benefit of Universal Low Titer Type O Screening. USCENTCOM 步行血库的绩效基准和普及低滴度 O 型血筛查的预期效益。
Pub Date : 2024-04-25 DOI: 10.1177/00031348241248798
Andrew Hall, Alexander Alba, C. Olsen, Nicholas Greene, Kasey Hales, Darienne DeWalt, Brendon Drew, Ryan Comes, Matthew Hanson
The walking blood bank (WBB) is a system for emergency blood acquisition from nearby donors if a patient's blood needs exceed the immediate supply. USCENTCOM medical units will perform a walking blood bank if immediate blood requirements exceed the local supply. A benchmark WBB performance time was needed to provide a training goal for military WBB exercises. An expeditionary WBB performance time benchmark was created from prospective measurements of USCENTCOM medical unit performance times over 9 months. The mean total time, and new performance benchmark, for a WBB in USCENTCOM was 41.4 min +/- 13.2 min. USCENTCOM time from donor arrival to a transfusable unit mean time was 34.4 +/- 12.1 min. Expeditionary medical units conducting a WBB should expect to meet or exceed the provided benchmark.
步行血库(WBB)是在病人的血液需求超过即时供应量时,从附近献血者处紧急获取血液的系统。如果急需的血液超过了当地的供应量,USCENTCOM 医疗单位将执行步行血库。需要一个 WBB 性能时间基准,以便为军事 WBB 演习提供一个训练目标。通过对 USCENTCOM 医疗单位在 9 个月内的执行时间进行前瞻性测量,创建了远征 WBB 执行时间基准。USCENTCOM 的 WBB 平均总时间和新的性能基准为 41.4 分钟 +/- 13.2 分钟。USCENTCOM 从捐献者到达到可输血单位的平均时间为 34.4 +/- 12.1 分钟。进行 WBB 的远征医疗单位应达到或超过所提供的基准。
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引用次数: 0
Hospital Quality Mediates Impact of Care Fragmentation Following Elective Colectomy. 医院质量对择期结肠切除术后护理分散的影响具有中介作用。
Pub Date : 2024-04-24 DOI: 10.1177/00031348241248795
Sara Sakowitz, S. Bakhtiyar, Saad Mallick, N. Y. Cho, Shineui Kim, Nguyen K. Le, Hanjoo Lee, P. Benharash
BACKGROUNDReadmission at a non-index hospital, or care fragmentation (CF), has been previously linked to greater morbidity and resource utilization. However, a contemporary evaluation of the impact of CF on readmission outcomes following elective colectomy is lacking. We additionally sought to evaluate the role of hospital quality in mediating the effect of CF.METHODSAll records for adults undergoing elective colectomy were tabulated from the 2016 to 2020 Nationwide Readmissions Database. Patients readmitted non-electively within 30 days to a non-index center comprised the CF cohort (others: Non-CF). Hierarchical mixed-effects models were constructed to ascertain risk-adjusted rates of major adverse events (MAEs, a composite of in-hospital mortality and any complication) attributable to center-level effects. Hospitals with risk-adjusted MAE rates ≥50th percentile were considered Low-Quality Hospitals (LQHs) (others: High-Quality Hospitals [HQHs]).RESULTSOf 68,185 patients readmitted non-electively within 30 days, 8968 (13.2%) were categorized as CF. On average, CF was older, of greater comorbidity burden, and more often underwent colectomy for cancer, relative to Non-CF. Following risk adjustment, CF remained independently associated with greater likelihood of MAE (adjusted odds ratio [AOR] 1.16, 95% Confidence Interval [CI] 1.05-1.27) and per-patient expenditures (β+$2,280, CI +$1080-3490). Further, readmission to non-index LQH was linked with significantly increased odds of MAE, following initial care at HQH (AOR 1.43, CI 1.03-1.99) and LQH (AOR 1.72, CI 1.30-2.28; Reference: Non-CF).CONCLUSIONSCare fragmentation was associated with greater morbidity and resource utilization at readmission following elective colectomy. Further, rehospitalization at non-index LQH conferred significantly inferior outcomes. Novel efforts are needed to improve continuity of care.
背景在非指标医院再入院(或称护理分散(CF))与更高的发病率和资源利用率有关。然而,目前还缺乏关于非指数医院对择期结肠切除术后再入院结果的影响的评估。我们还试图评估医院质量在调解 CF 影响方面的作用。方法从 2016 年至 2020 年全国再入院数据库中统计了所有接受择期结肠切除术的成人记录。30天内再次非选择性入院至非指数中心的患者组成CF队列(其他:非CF)。我们构建了层次混合效应模型,以确定可归因于中心水平效应的主要不良事件(MAEs,院内死亡率和任何并发症的复合体)风险调整率。风险调整后主要不良事件发生率≥第50百分位数的医院被视为低质量医院(LQHs)(其他医院:高质量医院[HQHs])。结果 在68185名30天内非选择性再入院的患者中,8968人(13.2%)被归类为CF。与非结肠癌患者相比,结肠癌患者平均年龄较大,合并症较多,更常因癌症接受结肠切除术。经过风险调整后,CF 仍与更高的 MAE 可能性(调整后的几率比 [AOR] 1.16,95% 置信区间 [CI] 1.05-1.27)和患者人均支出(β+2280 美元,CI +1080-3490 美元)独立相关。此外,在HQH(AOR为1.43,CI为1.03-1.99)和LQH(AOR为1.72,CI为1.30-2.28;参考:非CF)接受初始治疗后,再次入院到非指标LQH与MAE几率显著增加有关。此外,在非指标性 LQH 再入院会带来显著的不良后果。需要采取新的措施来改善护理的连续性。
{"title":"Hospital Quality Mediates Impact of Care Fragmentation Following Elective Colectomy.","authors":"Sara Sakowitz, S. Bakhtiyar, Saad Mallick, N. Y. Cho, Shineui Kim, Nguyen K. Le, Hanjoo Lee, P. Benharash","doi":"10.1177/00031348241248795","DOIUrl":"https://doi.org/10.1177/00031348241248795","url":null,"abstract":"BACKGROUND\u0000Readmission at a non-index hospital, or care fragmentation (CF), has been previously linked to greater morbidity and resource utilization. However, a contemporary evaluation of the impact of CF on readmission outcomes following elective colectomy is lacking. We additionally sought to evaluate the role of hospital quality in mediating the effect of CF.\u0000\u0000\u0000METHODS\u0000All records for adults undergoing elective colectomy were tabulated from the 2016 to 2020 Nationwide Readmissions Database. Patients readmitted non-electively within 30 days to a non-index center comprised the CF cohort (others: Non-CF). Hierarchical mixed-effects models were constructed to ascertain risk-adjusted rates of major adverse events (MAEs, a composite of in-hospital mortality and any complication) attributable to center-level effects. Hospitals with risk-adjusted MAE rates ≥50th percentile were considered Low-Quality Hospitals (LQHs) (others: High-Quality Hospitals [HQHs]).\u0000\u0000\u0000RESULTS\u0000Of 68,185 patients readmitted non-electively within 30 days, 8968 (13.2%) were categorized as CF. On average, CF was older, of greater comorbidity burden, and more often underwent colectomy for cancer, relative to Non-CF. Following risk adjustment, CF remained independently associated with greater likelihood of MAE (adjusted odds ratio [AOR] 1.16, 95% Confidence Interval [CI] 1.05-1.27) and per-patient expenditures (β+$2,280, CI +$1080-3490). Further, readmission to non-index LQH was linked with significantly increased odds of MAE, following initial care at HQH (AOR 1.43, CI 1.03-1.99) and LQH (AOR 1.72, CI 1.30-2.28; Reference: Non-CF).\u0000\u0000\u0000CONCLUSIONS\u0000Care fragmentation was associated with greater morbidity and resource utilization at readmission following elective colectomy. Further, rehospitalization at non-index LQH conferred significantly inferior outcomes. Novel efforts are needed to improve continuity of care.","PeriodicalId":325363,"journal":{"name":"The American Surgeon","volume":"59 9","pages":"31348241248795"},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140664532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Colorectal Anastomosis Versus Colostomy Creation in High MELD Patients: An ACS-NSQIP Analysis. 高 MELD 患者的结直肠吻合术与结肠造口术:ACS-NSQIP 分析。
Pub Date : 2024-04-24 DOI: 10.1177/00031348241248787
S. A. Karim, JustinJ Turcotte, Scott T Rehrig, C. Feather, J. Klune
BACKGROUNDLiver failure patients are at increased risk of surgical complications. The decision to perform a colonic anastomosis vs a colostomy in urgent colorectal surgery remains unclear.METHODSThe ACS-NSQIP database was queried for patients undergoing nonelective colorectal surgery between 2016 and 2018. MELD score was calculated and stratified into 3 groups. Subgroup analysis of the high-MELD group was performed.RESULTSHigher MELD scores were associated with significantly higher mortality. Colostomy formation was consistent between intermediate and high-MELD groups. In high-MELD patients, colonic anastomosis was associated with higher mortality than those receiving colostomy (41.1% vs 28.4%, P < .001). Patients receiving colostomy had higher rates of wound complications, but lower rates of return to OR and non-wound complications. Regression analysis revealed that colostomy formation remained an independent predictor of survival (mortality OR = .594, P < .001).DISCUSSIONHigh-MELD patients undergoing nonelective colorectal surgery have increased risk of complications such as mortality. Patients in this group receiving an anastomosis have increased complications and mortality, and may benefit from colostomy formation.
背景肝功能衰竭患者发生手术并发症的风险增加。在紧急结直肠手术中,结肠吻合术与结肠造口术的决定仍不明确。方法查询了 ACS-NSQIP 数据库中 2016 年至 2018 年间接受非选择性结直肠手术的患者。计算 MELD 评分并将其分为 3 组。结果MELD评分越高,死亡率越高。中MELD组和高MELD组的结肠造口形成情况一致。在高 MELD 患者中,结肠吻合术的死亡率高于接受结肠造口术的患者(41.1% vs 28.4%,P < .001)。接受结肠造口术的患者伤口并发症发生率较高,但返回手术室和非伤口并发症发生率较低。回归分析显示,结肠造口术的形成仍然是生存率的独立预测因素(死亡率 OR = .594,P < .001)。接受吻合术的这类患者的并发症和死亡率都会增加,可能会从结肠造口术中获益。
{"title":"Colorectal Anastomosis Versus Colostomy Creation in High MELD Patients: An ACS-NSQIP Analysis.","authors":"S. A. Karim, JustinJ Turcotte, Scott T Rehrig, C. Feather, J. Klune","doi":"10.1177/00031348241248787","DOIUrl":"https://doi.org/10.1177/00031348241248787","url":null,"abstract":"BACKGROUND\u0000Liver failure patients are at increased risk of surgical complications. The decision to perform a colonic anastomosis vs a colostomy in urgent colorectal surgery remains unclear.\u0000\u0000\u0000METHODS\u0000The ACS-NSQIP database was queried for patients undergoing nonelective colorectal surgery between 2016 and 2018. MELD score was calculated and stratified into 3 groups. Subgroup analysis of the high-MELD group was performed.\u0000\u0000\u0000RESULTS\u0000Higher MELD scores were associated with significantly higher mortality. Colostomy formation was consistent between intermediate and high-MELD groups. In high-MELD patients, colonic anastomosis was associated with higher mortality than those receiving colostomy (41.1% vs 28.4%, P < .001). Patients receiving colostomy had higher rates of wound complications, but lower rates of return to OR and non-wound complications. Regression analysis revealed that colostomy formation remained an independent predictor of survival (mortality OR = .594, P < .001).\u0000\u0000\u0000DISCUSSION\u0000High-MELD patients undergoing nonelective colorectal surgery have increased risk of complications such as mortality. Patients in this group receiving an anastomosis have increased complications and mortality, and may benefit from colostomy formation.","PeriodicalId":325363,"journal":{"name":"The American Surgeon","volume":"53 12","pages":"31348241248787"},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140662843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paradigm Shifts in Vascular Surgery: Analysis of the Top 100 Innovative and Disruptive Academic Publications. 血管外科的范式转变:血管外科的范式转变:100 篇最具创新性和颠覆性的学术论文分析》(Analysis of the Top 100 Innovative and Disruptive Academic Publications)。
Pub Date : 2024-04-24 DOI: 10.1177/00031348241248804
Shea P. Gallagher, Vanya Vojvodic, Joshua Dilday, Stephen Park, Chaiss Ugarte, Patrick McGillen, Anastasia Plotkin, Gregory A Magee, Kenji Inaba, Matthew Martin
BACKGROUNDDisruption score (DS) is a novel bibliometric created to identify research that shifts paradigms, which may be overlooked by citation count (CC). We analyzed the most disruptive, compared to the most cited, literature in vascular surgery, and hypothesized that DS and CC would not correlate.METHODSA PubMed search identified vascular surgery publications from 1954 to 2014. The publications were linked to the iCite NIH tool and DS algorithm to identify the top 100 studies by CC and DS, respectively. The publications were reviewed for study focus, design, and contribution, and subsequently compared.RESULTSA total of 56,640 publications were identified. The top 100 DS papers were frequently published in J Vasc Sur (43%) and Eur J Vasc Endovasc Surg (13%). The top 100 CC papers were frequently published in N Engl J Med (32%) and J Vasc Sur (20%). The most cited article is the fifth most disruptive; the most disruptive article is not in the top 100 cited papers. The DS papers had a higher mean DS than the CC papers (.17 vs .0001, P < .0001). The CC papers had a higher mean CC than the DS papers (866 vs 188, P < .0001). DS and CC are weakly correlated metrics (r = .22, P = .03).DISCUSSIONDS was weakly correlated with CC and captured a unique subset of literature that created paradigm shifts in vascular surgery. DS should be utilized as an adjunct to CC to avoid overlooking impactful research and influential researchers, and to measure true academic productivity.
背景中断评分(Disruption score,DS)是一种新颖的文献计量学方法,用于识别可能被引文次数(CC)忽略的改变研究范式的研究。我们分析了血管外科中最具破坏性的文献与被引次数最多的文献,并假设DS与CC并不相关。这些出版物与 iCite NIH 工具和 DS 算法相连接,以分别确定 CC 和 DS 排名前 100 位的研究。对这些出版物的研究重点、设计和贡献进行了审查,随后进行了比较。排名前 100 的 DS 论文经常发表在《J Vasc Sur》(43%)和《Eur J Vasc Endovasc Surg》(13%)上。前100篇CC论文经常发表在《N Engl J Med》(32%)和《J Vasc Sur》(20%)上。被引用次数最多的文章是干扰性排名第五的文章;干扰性最强的文章不在被引用次数前 100 的论文之列。DS论文的平均DS值高于CC论文(.17 vs .0001,P < .0001)。CC论文的平均CC值高于DS论文(866 vs 188,P < .0001)。DS 和 CC 是弱相关指标(r = .22, P = .03)。DS 应作为 CC 的辅助指标,以避免忽略有影响力的研究和有影响力的研究人员,并衡量真正的学术生产力。
{"title":"Paradigm Shifts in Vascular Surgery: Analysis of the Top 100 Innovative and Disruptive Academic Publications.","authors":"Shea P. Gallagher, Vanya Vojvodic, Joshua Dilday, Stephen Park, Chaiss Ugarte, Patrick McGillen, Anastasia Plotkin, Gregory A Magee, Kenji Inaba, Matthew Martin","doi":"10.1177/00031348241248804","DOIUrl":"https://doi.org/10.1177/00031348241248804","url":null,"abstract":"BACKGROUND\u0000Disruption score (DS) is a novel bibliometric created to identify research that shifts paradigms, which may be overlooked by citation count (CC). We analyzed the most disruptive, compared to the most cited, literature in vascular surgery, and hypothesized that DS and CC would not correlate.\u0000\u0000\u0000METHODS\u0000A PubMed search identified vascular surgery publications from 1954 to 2014. The publications were linked to the iCite NIH tool and DS algorithm to identify the top 100 studies by CC and DS, respectively. The publications were reviewed for study focus, design, and contribution, and subsequently compared.\u0000\u0000\u0000RESULTS\u0000A total of 56,640 publications were identified. The top 100 DS papers were frequently published in J Vasc Sur (43%) and Eur J Vasc Endovasc Surg (13%). The top 100 CC papers were frequently published in N Engl J Med (32%) and J Vasc Sur (20%). The most cited article is the fifth most disruptive; the most disruptive article is not in the top 100 cited papers. The DS papers had a higher mean DS than the CC papers (.17 vs .0001, P < .0001). The CC papers had a higher mean CC than the DS papers (866 vs 188, P < .0001). DS and CC are weakly correlated metrics (r = .22, P = .03).\u0000\u0000\u0000DISCUSSION\u0000DS was weakly correlated with CC and captured a unique subset of literature that created paradigm shifts in vascular surgery. DS should be utilized as an adjunct to CC to avoid overlooking impactful research and influential researchers, and to measure true academic productivity.","PeriodicalId":325363,"journal":{"name":"The American Surgeon","volume":"12 8","pages":"31348241248804"},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140663566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Postoperative COVID-19 Infection on 30-day Outcomes of Laparoscopic Cholecystectomy. 术后 COVID-19 感染对腹腔镜胆囊切除术 30 天疗效的影响
Pub Date : 2024-04-24 DOI: 10.1177/00031348241248800
Alexandra Moulton, Jessica K. Liu, Christian Miguel de Virgilio, J. Ozao-Choy, A. Moazzez
Introduction: Preoperative Coronavirus Disease 2019 (COVID-19) infections are associated with postoperative adverse outcomes. However, there is limited data on the impact of postoperative COVID-19 infection on postoperative outcomes of common general surgery procedures.Objective: To evaluate the impact of postoperative COVID-19 diagnosis on laparoscopic cholecystectomy outcomes.Methods: Patients with symptomatic cholelithiasis, acute cholecystitis, or gallstone pancreatitis who underwent laparoscopic cholecystectomy with or without intraoperative cholangiogram were identified using the 2021 National Surgical Quality Improvement Program (NSQIP) database. Patients were categorized into two groups: patients with and without a postoperative COVID-19 diagnosis. Coarsened Exact Matching was used to match the groups based on preoperative risk factors, and outcomes were compared.Results: A total of 47,948 patients were included. In the aggregate cohort, 31% were male, and mean age was 50 years. Age, BMI, smoking, COPD, CHF, preoperative sepsis, and ASA class were significantly different between the two groups. After matching, there were no differences in characteristics. 30-day morbidity (OR = 2.7, 95% CI 1.4-5.1), pneumonia (OR = 5.0, 95% CI 1.7-15.0), DVT (OR = 8.22, 95% CI 1.0-66), reoperation (OR = 9.3, 95% CI 1.2-73.8), and readmission (OR = 4.8, 95% CI 2.3-10.1) continued to be significantly worse in the matched cohort.Conclusion: Postoperative COVID-19 infection was associated with worse outcomes after laparoscopic cholecystectomy. These findings suggest that even postoperative COVID-19 diagnosis increases the risk for adverse outcomes in patients recovering from laparoscopic cholecystectomy and may indicate that precautions should be taken and new COVID-19 infections even after surgery should be closely monitored.
导言:术前冠状病毒病 2019(COVID-19)感染与术后不良后果有关。然而,关于术后COVID-19感染对普通普外科手术术后结果的影响的数据有限:评估术后 COVID-19 诊断对腹腔镜胆囊切除术结果的影响:方法:利用 2021 年国家外科质量改进计划 (NSQIP) 数据库,对有症状的胆石症、急性胆囊炎或胆石性胰腺炎患者进行鉴定,这些患者均接受了腹腔镜胆囊切除术,并进行或未进行术中胆管造影。患者分为两组:术后诊断为 COVID-19 和未诊断为 COVID-19 的患者。根据术前风险因素,采用粗化精确匹配法对两组患者进行匹配,并对结果进行比较:结果:共纳入 47948 名患者。结果:共纳入 47948 名患者,其中男性占 31%,平均年龄为 50 岁。两组患者的年龄、体重指数、吸烟、慢性阻塞性肺病、慢性心力衰竭、术前败血症和 ASA 分级有显著差异。配对后,两组特征无差异。匹配队列的 30 天发病率(OR = 2.7,95% CI 1.4-5.1)、肺炎(OR = 5.0,95% CI 1.7-15.0)、深静脉血栓(OR = 8.22,95% CI 1.0-66)、再次手术(OR = 9.3,95% CI 1.2-73.8)和再次入院(OR = 4.8,95% CI 2.3-10.1)仍明显低于匹配队列:结论:术后COVID-19感染与腹腔镜胆囊切除术后较差的预后有关。结论:术后COVID-19感染与腹腔镜胆囊切除术后不良预后相关。这些发现表明,即使术后诊断出COVID-19也会增加腹腔镜胆囊切除术后患者出现不良预后的风险,因此应采取预防措施,并密切监测术后新的COVID-19感染。
{"title":"The Impact of Postoperative COVID-19 Infection on 30-day Outcomes of Laparoscopic Cholecystectomy.","authors":"Alexandra Moulton, Jessica K. Liu, Christian Miguel de Virgilio, J. Ozao-Choy, A. Moazzez","doi":"10.1177/00031348241248800","DOIUrl":"https://doi.org/10.1177/00031348241248800","url":null,"abstract":"Introduction: Preoperative Coronavirus Disease 2019 (COVID-19) infections are associated with postoperative adverse outcomes. However, there is limited data on the impact of postoperative COVID-19 infection on postoperative outcomes of common general surgery procedures.Objective: To evaluate the impact of postoperative COVID-19 diagnosis on laparoscopic cholecystectomy outcomes.Methods: Patients with symptomatic cholelithiasis, acute cholecystitis, or gallstone pancreatitis who underwent laparoscopic cholecystectomy with or without intraoperative cholangiogram were identified using the 2021 National Surgical Quality Improvement Program (NSQIP) database. Patients were categorized into two groups: patients with and without a postoperative COVID-19 diagnosis. Coarsened Exact Matching was used to match the groups based on preoperative risk factors, and outcomes were compared.Results: A total of 47,948 patients were included. In the aggregate cohort, 31% were male, and mean age was 50 years. Age, BMI, smoking, COPD, CHF, preoperative sepsis, and ASA class were significantly different between the two groups. After matching, there were no differences in characteristics. 30-day morbidity (OR = 2.7, 95% CI 1.4-5.1), pneumonia (OR = 5.0, 95% CI 1.7-15.0), DVT (OR = 8.22, 95% CI 1.0-66), reoperation (OR = 9.3, 95% CI 1.2-73.8), and readmission (OR = 4.8, 95% CI 2.3-10.1) continued to be significantly worse in the matched cohort.Conclusion: Postoperative COVID-19 infection was associated with worse outcomes after laparoscopic cholecystectomy. These findings suggest that even postoperative COVID-19 diagnosis increases the risk for adverse outcomes in patients recovering from laparoscopic cholecystectomy and may indicate that precautions should be taken and new COVID-19 infections even after surgery should be closely monitored.","PeriodicalId":325363,"journal":{"name":"The American Surgeon","volume":"17 17","pages":"31348241248800"},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140660496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emergency Surgical Treatment and Triage: Targeting Optimal Outcomes for Emergency Surgical Patients From Index Encounter Through Definitive Care. 急诊外科治疗和分诊:为急诊外科病人提供从初次就诊到最终治疗的最佳结果。
Pub Date : 2024-04-24 DOI: 10.1177/00031348241248783
Jaclyn Kliewer, Ilko Luque, Mariel A Javier, Amanda Moorefield, Hector Mendez, Zulmari Martinez, Jacob Oster, Alexis Rangel, Orlando Morejón
BACKGROUNDPatients with emergency surgical conditions (ESCs) experience higher complication rates than those without emergency conditions. Our purpose was to improve time-based key performance indicators (KPIs) of care for ESC patients, including diagnostic workup, empiric stabilization, and referral to definitive care.METHODSA rapid response program (ESTAT) was developed to screen for and coordinate optimal, timely care for a spectrum of high-risk ESCs, from the patient's index clinical encounter up to definitive care. The Mann-Whitney test assessed whether any differences in KPIs were statistically significant (P < .05) before compared to after the implementation of ESTAT.RESULTS98 patients were identified: 44 in ESTAT group (70% age ≥55, 57% male); 54 in control group (57% age ≥55, 44% male). There were significant decreases from time of index clinical encounter to resuscitation (5 min. vs 34 min., P < .001), to diagnostic imaging (52 min. vs 1 hr. 19 min., P = .004), and to definitive care (2 hr. 17 min. vs 3 hr. 51 min., P = .007) in the ESTAT group compared to the control group, respectively.DISCUSSIONImproving time-based KPIs for delivery of clinical services is a common goal of medical emergency response systems (MERS) in numerous specialties. Implementation of an ESTAT program provides a screening tool for at-risk patients and reduces time to stabilize, diagnose and triage to definitive surgical intervention. These time benefits may ultimately translate to reduced complication rates for ESC patients. ESTAT may also represent a patient onboarding mechanism for surgical specialty verification programs promoted by quality improvement committees of various professional societies.
背景与非急诊患者相比,急诊手术患者的并发症发生率更高。我们的目的是改善急诊手术患者护理的基于时间的关键绩效指标(KPIs),包括诊断工作、经验性病情稳定和转诊至最终护理。方法我们开发了一项快速反应计划(ESTAT),用于筛查和协调从患者的首次临床就诊到最终护理的一系列高风险急诊手术患者的最佳及时护理。通过 Mann-Whitney 检验评估了实施 ESTAT 前与实施 ESTAT 后在关键绩效指标上的差异是否具有统计学意义(P < .05):ESTAT组44人(70%年龄≥55岁,57%为男性);对照组54人(57%年龄≥55岁,44%为男性)。与对照组相比,ESTAT 组患者从发病到复苏(5 分钟 vs 34 分钟,P < .001)、到影像诊断(52 分钟 vs 1 小时 19 分钟,P = .004)以及到最终治疗(2 小时 17 分钟 vs 3 小时 51 分钟,P = .007)的时间分别明显缩短。实施 ESTAT 计划可为高危患者提供筛查工具,并缩短稳定、诊断和分流至明确手术干预的时间。这些时间上的优势最终可能会降低 ESC 患者的并发症发生率。ESTAT还可作为患者入院机制,用于各专业学会质量改进委员会推广的外科专科验证计划。
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引用次数: 0
Back on the Streets: Examining Emergency Department Return Rates for Unhoused Patients Discharged After Trauma. 重返街头:研究急诊科中外伤后出院的无家可归病人的返回率。
Pub Date : 2024-04-24 DOI: 10.1177/00031348241248691
Stephen Park, Sean M. Kim, Hye Kwang Kim, Emiliano Tabarsi, Brian Hom, Shea P. Gallagher, Chaiss Ugarte, Damon Clark, M. Schellenberg, Matthew Martin, Kenji Inaba, K. Matsushima
BACKGROUNDThe unhoused population is at high risk for traumatic injuries and faces unique challenges in accessing follow-up care. However, there is scarce data regarding differences in Emergency Department (ED) return rates and reasons for return between unhoused and housed patients.METHODSWe conducted a 3-year retrospective cohort study at a level-1 trauma center in a large metropolitan area. All patients who presented to the ED with traumatic injuries and were discharged without hospital admission were included in the study. The primary outcome was ED returns for trauma-related complications or new traumatic events <6 months after discharge. Patient characteristics and study outcomes were compared between housed and unhoused groups.RESULTSA total of 4184 patients were identified, of which 20.3% were unhoused. Compared to housed, unhoused patients were more likely to return to the ED (18.8% vs 13.9%, P < .001), more likely to return for trauma-related complications (4.6% vs 3.1%, P = .045), more likely to return with new trauma (7.1% vs 2.8%, P < .001), and less likely to return for scheduled wound checks (2.5% vs 4.3%, P = .012). Of the patients who returned with trauma-related complications, unhoused patients had a higher proportion of wound infection (20.5% vs 5.7%, P = .008). In the regression analysis, unhoused status was associated with increased odds of ED return with new trauma and decreased odds of return for scheduled wound checks.CONCLUSIONSThis study observed significant disparities between unhoused and housed patients after trauma. Our results suggest that inadequate follow-up in unhoused patients may contribute to further ED return.
背景无住房人群是创伤性损伤的高危人群,在获得后续治疗方面面临着独特的挑战。然而,关于无住所患者和有住所患者在急诊科(ED)复诊率和复诊原因方面的差异的数据却很少。所有在急诊室就诊的外伤患者均被纳入研究。研究的主要结果是患者在出院后 6 个月内因创伤相关并发症或新的创伤事件而重返急诊室。结果共确定了 4184 名患者,其中 20.3% 的患者无住房。与有住所的患者相比,无住所的患者更有可能返回急诊室(18.8% vs 13.9%,P < .001),更有可能因创伤相关并发症返回急诊室(4.6% vs 3.1%,P = .045),更有可能因新的创伤返回急诊室(7.1% vs 2.8%,P < .001),更不可能返回急诊室进行定期伤口检查(2.5% vs 4.3%,P = .012)。在因创伤相关并发症而复诊的患者中,无住房患者的伤口感染比例更高(20.5% 对 5.7%,P = .008)。在回归分析中,无住房患者因新创伤返回急诊室的几率增加,而返回急诊室接受预定伤口检查的几率降低。我们的研究结果表明,对无住房患者的随访不足可能会导致再次返回急诊室。
{"title":"Back on the Streets: Examining Emergency Department Return Rates for Unhoused Patients Discharged After Trauma.","authors":"Stephen Park, Sean M. Kim, Hye Kwang Kim, Emiliano Tabarsi, Brian Hom, Shea P. Gallagher, Chaiss Ugarte, Damon Clark, M. Schellenberg, Matthew Martin, Kenji Inaba, K. Matsushima","doi":"10.1177/00031348241248691","DOIUrl":"https://doi.org/10.1177/00031348241248691","url":null,"abstract":"BACKGROUND\u0000The unhoused population is at high risk for traumatic injuries and faces unique challenges in accessing follow-up care. However, there is scarce data regarding differences in Emergency Department (ED) return rates and reasons for return between unhoused and housed patients.\u0000\u0000\u0000METHODS\u0000We conducted a 3-year retrospective cohort study at a level-1 trauma center in a large metropolitan area. All patients who presented to the ED with traumatic injuries and were discharged without hospital admission were included in the study. The primary outcome was ED returns for trauma-related complications or new traumatic events <6 months after discharge. Patient characteristics and study outcomes were compared between housed and unhoused groups.\u0000\u0000\u0000RESULTS\u0000A total of 4184 patients were identified, of which 20.3% were unhoused. Compared to housed, unhoused patients were more likely to return to the ED (18.8% vs 13.9%, P < .001), more likely to return for trauma-related complications (4.6% vs 3.1%, P = .045), more likely to return with new trauma (7.1% vs 2.8%, P < .001), and less likely to return for scheduled wound checks (2.5% vs 4.3%, P = .012). Of the patients who returned with trauma-related complications, unhoused patients had a higher proportion of wound infection (20.5% vs 5.7%, P = .008). In the regression analysis, unhoused status was associated with increased odds of ED return with new trauma and decreased odds of return for scheduled wound checks.\u0000\u0000\u0000CONCLUSIONS\u0000This study observed significant disparities between unhoused and housed patients after trauma. Our results suggest that inadequate follow-up in unhoused patients may contribute to further ED return.","PeriodicalId":325363,"journal":{"name":"The American Surgeon","volume":"17 4","pages":"31348241248691"},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140660345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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The American Surgeon
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