{"title":"Determinant Factors of Cognitive Frailty in Elderly Patients","authors":"","doi":"10.7454/jpdi.v9i4.1021","DOIUrl":"https://doi.org/10.7454/jpdi.v9i4.1021","url":null,"abstract":"","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44227111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Second-Line Therapy Tyrosine Kinase Inhibitor for Chronic Phase Chronic Myeloid Leukemia Resistant to Imatinib","authors":"","doi":"10.7454/jpdi.v9i4.1026","DOIUrl":"https://doi.org/10.7454/jpdi.v9i4.1026","url":null,"abstract":"","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71340690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Kecubung Intoxication: A Case Report on A 16-Year-Old Male at Kuningan District","authors":"","doi":"10.7454/jpdi.v9i4.1025","DOIUrl":"https://doi.org/10.7454/jpdi.v9i4.1025","url":null,"abstract":"","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45807693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of Garlic Extract (Allium sativum) to Reduce Level of Malondialdehyde Serum and Improve Quality of Life in Patients with Chronic Hemodialysis: A Randomized Double-Blind Placebo-Controlled Trial","authors":"","doi":"10.7454/jpdi.v9i4.1022","DOIUrl":"https://doi.org/10.7454/jpdi.v9i4.1022","url":null,"abstract":"","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44384910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Advance Care Planning on Heart Failure Patients: An Evidence Based Case Report","authors":"","doi":"10.7454/jpdi.v9i4.1024","DOIUrl":"https://doi.org/10.7454/jpdi.v9i4.1024","url":null,"abstract":"","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46403468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pemberian Antibiotik Dini Berpengaruh terhadap Mortalitas COVID-19?","authors":"","doi":"10.7454/jpdi.v9i4.1010","DOIUrl":"https://doi.org/10.7454/jpdi.v9i4.1010","url":null,"abstract":"","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48696268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Rizka, Helda Helda, Findy Prasetyawaty, Arcita Hanjani
{"title":"Prevalensi Sindrom Geriatri pada Pasien Kanker Berusia Lanjut Pra Kemoterapi","authors":"A. Rizka, Helda Helda, Findy Prasetyawaty, Arcita Hanjani","doi":"10.7454/jpdi.v9i3.854","DOIUrl":"https://doi.org/10.7454/jpdi.v9i3.854","url":null,"abstract":"","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47982016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pandemi COVID-19 memberikan dampak besar di bidang kesehatan, baik dari segi pembiayaan kesehatan ataupun beban penyedia layanan kesehatan. Depresi, kecemasan akan status kesehatan keluarga, rasa takut tertular virus, serta berkurangnya interaksi sosial, merupakan beban mental yang dialami tenaga medis.
{"title":"Dampak Pandemi COVID-19 terhadap Mahasiswa Kedokteran","authors":"Amanda Utari","doi":"10.7454/jpdi.v9i3.898","DOIUrl":"https://doi.org/10.7454/jpdi.v9i3.898","url":null,"abstract":"Pandemi COVID-19 memberikan dampak besar di bidang kesehatan, baik dari segi pembiayaan kesehatan ataupun beban penyedia layanan kesehatan. Depresi, kecemasan akan status kesehatan keluarga, rasa takut tertular virus, serta berkurangnya interaksi sosial, merupakan beban mental yang dialami tenaga medis.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43756247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction. The lactate/albumin ratio is an inflammatory biomarker that has been widely used and suggested as a predictor of mortality in patients with sepsis and septic shock. However, the results are inconsistent. This meta-analysis aimed to evaluate the prognostic value of lactate/albumin ratio as a predictor of mortality in patients with sepsis and septic shock. Methods. The study protocol was registered with PROSPERO (CRD42021286242). A literature search was performed using PubMed, Ovid EMBASE, Ovid MEDLINE, SCOPUS, and Web of Sciences to find all studies evaluating the association between lactate/albumin ratio and mortality in patients with sepsis and septic shock. Meta-analysis was performed to synthesize the overall Standardized Mean Difference (SMD) of the lactate/albumin ratio and the pooled Odds Ratio (OR) for mortality with 95% confidence intervals (95% CI). Heterogeneity was assessed using I 2 . Publication bias was assessed quantitatively with Egger’s test. Analysis was performed using Stata version 16. Results. Seven studies (n=10,264 patients) were included in the meta-analysis. The meta-analysis results showed that non-survivor had a higher lactate/albumin ratio than survivor (random-effects model; SMD 1.47; 95% CI 0,91-2,04; p <0.001). Higher lactate/albumin ratio was associated with an increased mortality in sepsis and septic shock patients (fixed-effects model; OR 1.49 (95% CI 1.37-1.62); p <0.001). Conclusions. High lactate/albumin ratio was associated with mortality in sepsis and septic shock patients. Thus, lactate/ albumin ratio can be used as a predictor biomarker in predicting mortality for sepsis and septic shock patients.
介绍。乳酸/白蛋白比率是一种炎症生物标志物，已被广泛使用，并被认为是脓毒症和感染性休克患者死亡率的预测指标。然而，结果是不一致的。本荟萃分析旨在评估乳酸/白蛋白比率作为脓毒症和感染性休克患者死亡率预测因子的预后价值。方法。研究方案已在PROSPERO注册(CRD42021286242)。通过PubMed、Ovid EMBASE、Ovid MEDLINE、SCOPUS和Web of Sciences进行文献检索，找到所有评估脓毒症和感染性休克患者乳酸/白蛋白比率与死亡率之间关系的研究。进行meta分析，综合乳酸/白蛋白比率的总体标准化平均差(SMD)和死亡率的合并优势比(OR)， 95%置信区间(95% CI)。使用i2评估异质性。用Egger’s检验定量评估发表偏倚。使用Stata version 16进行分析。结果。meta分析包括7项研究(n= 10264例患者)。荟萃分析结果显示，非幸存者的乳酸/白蛋白比率高于幸存者(随机效应模型;SMD 1.47;95% ci为0,91-2,04;p < 0.001)。较高的乳酸/白蛋白比率与脓毒症和感染性休克患者死亡率增加有关(固定效应模型;或1.49 (95% ci 1.37-1.62);p < 0.001)。结论。高乳酸/白蛋白比率与败血症和感染性休克患者的死亡率相关。因此，乳酸/白蛋白比值可作为预测脓毒症和感染性休克患者死亡率的预测指标。
{"title":"Rasio Laktat/Albumin sebagai Prediktor Mortalitas pada Pasien dengan Sepsis dan Syok Sepsis: Studi Meta-Analisis","authors":"F. Baihaqi, Dinda Olinda Delarosa, Rezki Ramadhan","doi":"10.7454/jpdi.v9i3.718","DOIUrl":"https://doi.org/10.7454/jpdi.v9i3.718","url":null,"abstract":"Introduction. The lactate/albumin ratio is an inflammatory biomarker that has been widely used and suggested as a predictor of mortality in patients with sepsis and septic shock. However, the results are inconsistent. This meta-analysis aimed to evaluate the prognostic value of lactate/albumin ratio as a predictor of mortality in patients with sepsis and septic shock. Methods. The study protocol was registered with PROSPERO (CRD42021286242). A literature search was performed using PubMed, Ovid EMBASE, Ovid MEDLINE, SCOPUS, and Web of Sciences to find all studies evaluating the association between lactate/albumin ratio and mortality in patients with sepsis and septic shock. Meta-analysis was performed to synthesize the overall Standardized Mean Difference (SMD) of the lactate/albumin ratio and the pooled Odds Ratio (OR) for mortality with 95% confidence intervals (95% CI). Heterogeneity was assessed using I 2 . Publication bias was assessed quantitatively with Egger’s test. Analysis was performed using Stata version 16. Results. Seven studies (n=10,264 patients) were included in the meta-analysis. The meta-analysis results showed that non-survivor had a higher lactate/albumin ratio than survivor (random-effects model; SMD 1.47; 95% CI 0,91-2,04; p <0.001). Higher lactate/albumin ratio was associated with an increased mortality in sepsis and septic shock patients (fixed-effects model; OR 1.49 (95% CI 1.37-1.62); p <0.001). Conclusions. High lactate/albumin ratio was associated with mortality in sepsis and septic shock patients. Thus, lactate/ albumin ratio can be used as a predictor biomarker in predicting mortality for sepsis and septic shock patients.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46099461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analisis Faktor Risiko Gastro-Esophageal Reflux Disease di Era Pandemi COVID-19 pada Mahasiswa Program Pendidikan Dokter Spesialis Fakultas Kedokteran Universitas Brawijaya","authors":"P. Sakti, Syifa Mustika","doi":"10.7454/jpdi.v9i3.793","DOIUrl":"https://doi.org/10.7454/jpdi.v9i3.793","url":null,"abstract":"","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44797459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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