Hanna Lianti Afladhia, Rahmat Cahyanur, Sri Wahdini, Andhika Rachman
Latar Belakang: Nyeri merupakan salah satu keluhan paling banyak serta mengganggu kualitas hidup pasien kanker. Beberapa penelitian merekomendasikan intervensi multimodal yang mengkombinasikan antara terapi farmakologis dan nonfarmakologis. Salah satu pilihan tatalaksana nonfarmakologis yang dapat dipertimbangkan adalah terapi akupunktur.Tujuan: Tinjauan kasus berbasis bukti ini disusun untuk mengkaji efektivitas terapi akupunktur terhadap penurunan intensitas nyeri pada pasien dengan nyeri kanker.Metode: Pencarian dilakukan di tiga database (PubMed, Scopus, dan Embase). Kata kunci yang digunakan adalah cancer pain, malignant pain, acupuncture, acupuncture therapy, pain intensity, pain assessment, pain scale. Telaah kritis dilakukan dengan menggunakan panduan dari University of Oxford Centre for Evidence-based Medicine.Hasil: Diperoleh 4 artikel yang relevan dengan pertanyaan klinis. Terapi akupuntur secara konsisten menunjukkan penurunan intensitas nyeri, waktu onset nyeri yang lebih pendek, penurunan dosis dan jumlah analgesik yang dikonsumsi, serta kualitas hidup yang lebih baik dengan efek samping yang minimal, dibandingkan dengan terapi obat saja.Kesimpulan: Terapi akupunktur dapat dipertimbangkan sebagai terapi komplementer dalam penatalaksanaan nyeri kanker, namun tidak untuk menggantikan protokol standar nyeri. Keputusan klinis dalam menerapkan terapi akupunktur pada pasien perlu menilai preferensi pasien, aksesibilitas, serta efektivitas biaya.Kata Kunci: akupunktur, nyeri kanker, intensitas nyeri
{"title":"Efektivitas Terapi Akupunktur terhadap Penurunan Intensitas Nyeri pada Pasien dengan Nyeri Kanker","authors":"Hanna Lianti Afladhia, Rahmat Cahyanur, Sri Wahdini, Andhika Rachman","doi":"10.7454/jpdi.v9i3.797","DOIUrl":"https://doi.org/10.7454/jpdi.v9i3.797","url":null,"abstract":"Latar Belakang: Nyeri merupakan salah satu keluhan paling banyak serta mengganggu kualitas hidup pasien kanker. Beberapa penelitian merekomendasikan intervensi multimodal yang mengkombinasikan antara terapi farmakologis dan nonfarmakologis. Salah satu pilihan tatalaksana nonfarmakologis yang dapat dipertimbangkan adalah terapi akupunktur.Tujuan: Tinjauan kasus berbasis bukti ini disusun untuk mengkaji efektivitas terapi akupunktur terhadap penurunan intensitas nyeri pada pasien dengan nyeri kanker.Metode: Pencarian dilakukan di tiga database (PubMed, Scopus, dan Embase). Kata kunci yang digunakan adalah cancer pain, malignant pain, acupuncture, acupuncture therapy, pain intensity, pain assessment, pain scale. Telaah kritis dilakukan dengan menggunakan panduan dari University of Oxford Centre for Evidence-based Medicine.Hasil: Diperoleh 4 artikel yang relevan dengan pertanyaan klinis. Terapi akupuntur secara konsisten menunjukkan penurunan intensitas nyeri, waktu onset nyeri yang lebih pendek, penurunan dosis dan jumlah analgesik yang dikonsumsi, serta kualitas hidup yang lebih baik dengan efek samping yang minimal, dibandingkan dengan terapi obat saja.Kesimpulan: Terapi akupunktur dapat dipertimbangkan sebagai terapi komplementer dalam penatalaksanaan nyeri kanker, namun tidak untuk menggantikan protokol standar nyeri. Keputusan klinis dalam menerapkan terapi akupunktur pada pasien perlu menilai preferensi pasien, aksesibilitas, serta efektivitas biaya.Kata Kunci: akupunktur, nyeri kanker, intensitas nyeri","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41555015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hubungan antara Stres Selama Pandemi COVID-19 dengan Kejadian Sindrom Dispepsia pada Mahasiswa Kedokteran Tahun Pertama","authors":"W. Rahmi, Yulistini Yulistini, Arina Widya Murni","doi":"10.7454/jpdi.v9i3.684","DOIUrl":"https://doi.org/10.7454/jpdi.v9i3.684","url":null,"abstract":"","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41532960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Case of COVID-19 reinfection are related to immune factors in patients who have recovered by the natural course of the infecting pathogen. However, the chance of COVID-19 reinfection are still not well established. This review aimed to discuss about reinfection-related studies, including causes and clinical manifestations, and reinfection management. Reinfection happens when a patient is infected by the SARS-CoV-2 virus, which has a different genome from previous infection. Although the comparison of clinical manifestation between reinfection and the previous infection is not clear, it is believed that vulnerable populations may have worse outcomes. Vaccination is the main option to reduce the severity of reinfection. Further studies are needed to understand the mechanisms and management of COVID-19 reinfection. Thus, the development of COVID-19 treatment and vaccine can be more effective .
{"title":"Ancaman Reinfeksi COVID-19: Tinjauan dari Bukti Pustaka","authors":"M. Adnan, Ana Fauziyati","doi":"10.7454/jpdi.v9i3.539","DOIUrl":"https://doi.org/10.7454/jpdi.v9i3.539","url":null,"abstract":"Case of COVID-19 reinfection are related to immune factors in patients who have recovered by the natural course of the infecting pathogen. However, the chance of COVID-19 reinfection are still not well established. This review aimed to discuss about reinfection-related studies, including causes and clinical manifestations, and reinfection management. Reinfection happens when a patient is infected by the SARS-CoV-2 virus, which has a different genome from previous infection. Although the comparison of clinical manifestation between reinfection and the previous infection is not clear, it is believed that vulnerable populations may have worse outcomes. Vaccination is the main option to reduce the severity of reinfection. Further studies are needed to understand the mechanisms and management of COVID-19 reinfection. Thus, the development of COVID-19 treatment and vaccine can be more effective .","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48978267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cosphiadi Irawan, Ricci Steven, Ralph Girson Gunarsa, Jeffry Beta Tenggara
Leukemia (LMA). Studi leukemia kesintasan pasien LMA yang diadmisi ruang rawat semi-isolasi. Studi kohort retrospektif menggunakan data sekunder rekam medis pasien yang terdiagnosis LMA pada Mochtar Riady Comprehensive Cancer Center ABSTRACT Introduction . Standard positive pressure isolation room is not yet widely available in Indonesia. In several private hospitals, current best practice is admitting patients to semi-isolation room with additional protective measures. Despite the limitation, this practice is considered safe and might benefit Acute Myeloid Leukemia (AML) patients. This study aimed to analyze the leukemic profile and survival in AML patients admitted to semi-isolation room. Methods . A retrospective cohort study was conducted using secondary data from medical record of AML patients diagnosed in Mochtar Riady Comprehensive Cancer Center between 2018 – 2020. Patients were divided into semi-isolation room group and not admitted to semi-isolation room group. Semi-isolation room patients who received standard chemotherapy regimen were further analyzed according to complication, outcome, and survival. Results. We included 45 AML patients, 53.3% were females, 42.2% in the 40-59 years age group, and 28.9% were AML-M2. Fifteen patients received standard chemotherapy regimen including D3A7, FLAG, ATRA-Daunorubicin-Cytarabine in semi-isolation room, 60% of them had complete remission after treatment completion. Patients who not admitted to semi-isolation room received conservative treatments including hydroxyurea, mercaptopurine, cytarabine cytoreduction, and decitabine. Among patients in semi-isolation room, 41.2% had sepsis and 29.4 % had septic shock, with most of the sources coming from bloodstream infection (80%), Acinetobacter baumannii remained the most prevalent microorganism. Treatment outcomes showed median Progression Free Survival (PFS) of 11 months, 1-year survival was 47%, and 2-year survival was 27%. Conclusions. In countries with limited standard isolation room, treatment of AML patients in semi-isolation room with infection control protocol could be considered in order to give the standard induction chemotherapy regimen. Although there was an infection risk, strict isolation policy produced good response (60% complete remission).
{"title":"Luaran Hasil Leukemia Mieloid Akut yang Menjalani Terapi pada Ruang Kemoterapi Semi-Isolasi","authors":"Cosphiadi Irawan, Ricci Steven, Ralph Girson Gunarsa, Jeffry Beta Tenggara","doi":"10.7454/jpdi.v9i3.857","DOIUrl":"https://doi.org/10.7454/jpdi.v9i3.857","url":null,"abstract":"Leukemia (LMA). Studi leukemia kesintasan pasien LMA yang diadmisi ruang rawat semi-isolasi. Studi kohort retrospektif menggunakan data sekunder rekam medis pasien yang terdiagnosis LMA pada Mochtar Riady Comprehensive Cancer Center ABSTRACT Introduction . Standard positive pressure isolation room is not yet widely available in Indonesia. In several private hospitals, current best practice is admitting patients to semi-isolation room with additional protective measures. Despite the limitation, this practice is considered safe and might benefit Acute Myeloid Leukemia (AML) patients. This study aimed to analyze the leukemic profile and survival in AML patients admitted to semi-isolation room. Methods . A retrospective cohort study was conducted using secondary data from medical record of AML patients diagnosed in Mochtar Riady Comprehensive Cancer Center between 2018 – 2020. Patients were divided into semi-isolation room group and not admitted to semi-isolation room group. Semi-isolation room patients who received standard chemotherapy regimen were further analyzed according to complication, outcome, and survival. Results. We included 45 AML patients, 53.3% were females, 42.2% in the 40-59 years age group, and 28.9% were AML-M2. Fifteen patients received standard chemotherapy regimen including D3A7, FLAG, ATRA-Daunorubicin-Cytarabine in semi-isolation room, 60% of them had complete remission after treatment completion. Patients who not admitted to semi-isolation room received conservative treatments including hydroxyurea, mercaptopurine, cytarabine cytoreduction, and decitabine. Among patients in semi-isolation room, 41.2% had sepsis and 29.4 % had septic shock, with most of the sources coming from bloodstream infection (80%), Acinetobacter baumannii remained the most prevalent microorganism. Treatment outcomes showed median Progression Free Survival (PFS) of 11 months, 1-year survival was 47%, and 2-year survival was 27%. Conclusions. In countries with limited standard isolation room, treatment of AML patients in semi-isolation room with infection control protocol could be considered in order to give the standard induction chemotherapy regimen. Although there was an infection risk, strict isolation policy produced good response (60% complete remission).","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43823632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michelle Frastica, Rudi Putranto, C. O. M. Jasirwan, Kresna Adhiatma
{"title":"Sindroma Kasabach-Merritt pada Hemangioma Hati: Laporan Kasus","authors":"Michelle Frastica, Rudi Putranto, C. O. M. Jasirwan, Kresna Adhiatma","doi":"10.7454/jpdi.v9i3.675","DOIUrl":"https://doi.org/10.7454/jpdi.v9i3.675","url":null,"abstract":"","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45262538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Edward Faisal, Shafira Puspadina, Rudi Putranto, Hamzah Shatri
Pain is the main symptom in cancer patients that needs to be addressed immediately because it can reduce the quality of life. Concern or the ineffectiveness of using one type of opioid makes it necessary for clinicians to understand how to rotate opioids. Therefore, this evidence-based case report was conducted to identify the effectiveness of opioid rotation and combined opioids for the cancer pain management through a literature search on three databases. Literature searching was performed by using Pubmed, Cochrane library, and EBSCO according to clinical inquiries. Of the 24 studies obtained, only one study met the criteria and was then critically assessed. The study found that pain score in both opioid rotation group (fentanyl transdermal) and combined opioids group (oral oxycodone and fentanyl transdermal) was decreased from 2.9 to 2.0 (p=0.22) and 3.0 to 1.8 (p<0.06), respectively. In addition, therapeutic success was achieved in 11 patients in the opioid rotation group and 12 patients in the combined opioids group (p=0.98). Based on the study, it can be concluded that opioid rotation is as effective as combined opioids in managing pain in cancer patients.
{"title":"Efektivitas Rotasi Opioid Dibandingkan Kombinasi Opioid untuk Mengobati Nyeri Kanker: Laporan Kasus Berbasis Bukti","authors":"Edward Faisal, Shafira Puspadina, Rudi Putranto, Hamzah Shatri","doi":"10.7454/jpdi.v9i2.736","DOIUrl":"https://doi.org/10.7454/jpdi.v9i2.736","url":null,"abstract":"Pain is the main symptom in cancer patients that needs to be addressed immediately because it can reduce the quality of life. Concern or the ineffectiveness of using one type of opioid makes it necessary for clinicians to understand how to rotate opioids. Therefore, this evidence-based case report was conducted to identify the effectiveness of opioid rotation and combined opioids for the cancer pain management through a literature search on three databases. Literature searching was performed by using Pubmed, Cochrane library, and EBSCO according to clinical inquiries. Of the 24 studies obtained, only one study met the criteria and was then critically assessed. The study found that pain score in both opioid rotation group (fentanyl transdermal) and combined opioids group (oral oxycodone and fentanyl transdermal) was decreased from 2.9 to 2.0 (p=0.22) and 3.0 to 1.8 (p<0.06), respectively. In addition, therapeutic success was achieved in 11 patients in the opioid rotation group and 12 patients in the combined opioids group (p=0.98). Based on the study, it can be concluded that opioid rotation is as effective as combined opioids in managing pain in cancer patients.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48325969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Penelitian Vera, dkk. menunjukkan bahwa lanjut usia (lansia) merupakan kelompok yang memiliki mortalitas tinggi akibat Coronavirus disease (COVID-19) dan didominasi oleh kelompok frail. Lee, dkk. merekomendasikan penggunaan status frailty ini sebagai identifikasi faktor risiko yang bisa dimodifikasi pada kelompok lansia, yang dikaitkan dengan derajat beratnya COVID-19. Frailty dihubungkan dengan respons imunitas yang sudah menurun akibat kegagalan regulasi sistem homeostasis, akibatnya pasien frail rentan terhadap adanya stresor lingkungan dan luaran yang jelek.
{"title":"Revaksinasi COVID-19 pada Kelompok Lansia dengan Frailty","authors":"Ika Fitriana","doi":"10.7454/jpdi.v9i2.829","DOIUrl":"https://doi.org/10.7454/jpdi.v9i2.829","url":null,"abstract":"Penelitian Vera, dkk. menunjukkan bahwa lanjut usia (lansia) merupakan kelompok yang memiliki mortalitas tinggi akibat Coronavirus disease (COVID-19) dan didominasi oleh kelompok frail. Lee, dkk. merekomendasikan penggunaan status frailty ini sebagai identifikasi faktor risiko yang bisa dimodifikasi pada kelompok lansia, yang dikaitkan dengan derajat beratnya COVID-19. Frailty dihubungkan dengan respons imunitas yang sudah menurun akibat kegagalan regulasi sistem homeostasis, akibatnya pasien frail rentan terhadap adanya stresor lingkungan dan luaran yang jelek.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43015339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kevin Hocin, Dinas Yudha Kusuma, Atit Puspitasari Dewi
Coronavirus disease 19 (COVID-19) can present as various symptoms, which range from asymptomatic to severe symptoms. We report a case of COVID-19 female patient with malaria co-infection who developed pericarditis complication. In this pandemic era, it is mandatory to rule out COVID-19. Coinfection with malaria will result in higher cytokine levels which lead to atypical complication , such as pericarditis. Prompt identification of atypical COVID-19 complications is essential as it can lower the mortality rate and reduce the duration of hospitalization.
{"title":"Infeksi SARS-CoV-2 dengan Komplikasi Perikarditis Akut bersamaan dengan Infeksi Malaria","authors":"Kevin Hocin, Dinas Yudha Kusuma, Atit Puspitasari Dewi","doi":"10.7454/jpdi.v9i2.615","DOIUrl":"https://doi.org/10.7454/jpdi.v9i2.615","url":null,"abstract":"Coronavirus disease 19 (COVID-19) can present as various symptoms, which range from asymptomatic to severe symptoms. We report a case of COVID-19 female patient with malaria co-infection who developed pericarditis complication. In this pandemic era, it is mandatory to rule out COVID-19. Coinfection with malaria will result in higher cytokine levels which lead to atypical complication , such as pericarditis. Prompt identification of atypical COVID-19 complications is essential as it can lower the mortality rate and reduce the duration of hospitalization.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43280117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction. It was reported that 11.2% out o f the 78,572 confirmed cases of COVID-19 in Indonesia was found in older people with a high mortality rate. There is no available data regarding functional and frailty status of these COVID-19 older patients. This study aimed to describe clinical profile of older COVID-19 patients in terms of geriatric aspect, in order to design better hospital policy for older patients in the COVID-19 isolation ward. Methods . This was a retrospective cohort study of confirmed COVID-19 patients aged >60 years which were admitted to Immanuel Teaching Hospital Bandung during the period of October 2020 - January 2021. C linical characteristic data, frailty status, mode of oxygen therapy , functional status (activity of daily living – ADL) during and after hospitalization, as well as patient hospitalization outcomes were recorded from the medical record. Results . There were 100 COVID-19 older patients, more than hal f were aged 60-70 years, most with not frail status. This study found that 74% of older patients had decreased ADL scores, once they got infected with COVID-19. We also found that 43% of COVID-19 older patients died during hospitalization, dominated by frail patients. Among COVID-19 older survivor , 55% had increased ADL score when discharged . A month later, only 25% patients had better ADL scores. Conclusion. Typical symptoms of COVID-19 are not always found in older patients. Apart from its deadly consequence and prolonged hospitalization, the impact of COVID-19 on older patients is decreased functional status, so special management policy for older COVID-19 patients should be considered.
{"title":"Profil Klinis Pasien COVID-19 Lansia yang Dirawat Inap di RS Immanuel Bandung","authors":"Vera Vera, Yossie Guventri Eka Suprana","doi":"10.7454/jpdi.v9i2.743","DOIUrl":"https://doi.org/10.7454/jpdi.v9i2.743","url":null,"abstract":"Introduction. It was reported that 11.2% out o f the 78,572 confirmed cases of COVID-19 in Indonesia was found in older people with a high mortality rate. There is no available data regarding functional and frailty status of these COVID-19 older patients. This study aimed to describe clinical profile of older COVID-19 patients in terms of geriatric aspect, in order to design better hospital policy for older patients in the COVID-19 isolation ward. Methods . This was a retrospective cohort study of confirmed COVID-19 patients aged >60 years which were admitted to Immanuel Teaching Hospital Bandung during the period of October 2020 - January 2021. C linical characteristic data, frailty status, mode of oxygen therapy , functional status (activity of daily living – ADL) during and after hospitalization, as well as patient hospitalization outcomes were recorded from the medical record. Results . There were 100 COVID-19 older patients, more than hal f were aged 60-70 years, most with not frail status. This study found that 74% of older patients had decreased ADL scores, once they got infected with COVID-19. We also found that 43% of COVID-19 older patients died during hospitalization, dominated by frail patients. Among COVID-19 older survivor , 55% had increased ADL score when discharged . A month later, only 25% patients had better ADL scores. Conclusion. Typical symptoms of COVID-19 are not always found in older patients. Apart from its deadly consequence and prolonged hospitalization, the impact of COVID-19 on older patients is decreased functional status, so special management policy for older COVID-19 patients should be considered.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41375286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Sofro, T. Raharja, Titis Hadiati, Linda Kartika Sari, Innawati Jusup
Introduction. Indonesia has the second largest HIV burden in Asia. The prevalence of depression in HIV/AIDS is 2-10 times higher than the general population, influenced by biological, environmental, psychological, and demographic factors. Data on the proportion of depression symptoms in HIV/AIDS patients and their relationship to biological factors are still limited, which needed for better treatment of HIV/AIDS. This study aimed to determine the prevalence of depression and its relationship to the biologic factors of ARV therapy (ART) in HIV/AIDS patients. Methods . Cross-sectional study was conducted among 142 HIV/AIDS patients undergoing ARV treatment at RSUP. Dr. Kariadi in January – March 2021. Demographic data, ART, ART type, side effects, ARV use duration, viral load, and CD4 cell count were obtained from medical records. The incidence of depression was assessed by the Beck Depression Inventory II (BDI-II). Results. The proportion of depression symptoms was 48.6%, consisting of mild depression (26.1%), moderate depression (17.6%), and severe depression (4.9%). Multivariate analysis resulted a significant relationship between the incidence of depression and biological factors, consisting of ART side effects, ART use duration, and CD4 cell count. Meanwhile, there was no significant relationship between the incidence of depression with the ART type and viral load. Conclusion. The proportion of depression symptoms in HIV patients undergoing ART is 48.6%. It is concluded that biological factors can affect the proportion of depression in patients with ART.
{"title":"Proporsi Gejala Depresi dan Hubungannya dengan Terapi ARV: Studi di Poliklinik VCT RSUP Dr. Kariadi","authors":"M. Sofro, T. Raharja, Titis Hadiati, Linda Kartika Sari, Innawati Jusup","doi":"10.7454/jpdi.v9i2.745","DOIUrl":"https://doi.org/10.7454/jpdi.v9i2.745","url":null,"abstract":"Introduction. Indonesia has the second largest HIV burden in Asia. The prevalence of depression in HIV/AIDS is 2-10 times higher than the general population, influenced by biological, environmental, psychological, and demographic factors. Data on the proportion of depression symptoms in HIV/AIDS patients and their relationship to biological factors are still limited, which needed for better treatment of HIV/AIDS. This study aimed to determine the prevalence of depression and its relationship to the biologic factors of ARV therapy (ART) in HIV/AIDS patients. Methods . Cross-sectional study was conducted among 142 HIV/AIDS patients undergoing ARV treatment at RSUP. Dr. Kariadi in January – March 2021. Demographic data, ART, ART type, side effects, ARV use duration, viral load, and CD4 cell count were obtained from medical records. The incidence of depression was assessed by the Beck Depression Inventory II (BDI-II). Results. The proportion of depression symptoms was 48.6%, consisting of mild depression (26.1%), moderate depression (17.6%), and severe depression (4.9%). Multivariate analysis resulted a significant relationship between the incidence of depression and biological factors, consisting of ART side effects, ART use duration, and CD4 cell count. Meanwhile, there was no significant relationship between the incidence of depression with the ART type and viral load. Conclusion. The proportion of depression symptoms in HIV patients undergoing ART is 48.6%. It is concluded that biological factors can affect the proportion of depression in patients with ART.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43460190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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