Pub Date : 2023-03-30DOI: 10.57125/fem.2023.03.30.01
Background: Artificial intelligence (AI), usually called machine intelligence, is a scientific field that allows robots thinking like people. The most common diseases that cause visual impairment and blindness, such as age-related macular degeneration (ARMD), cataract, glaucoma, and diabetic retinopathy (DR), have recently been subject to deep learning-based on AI screening and prediction models. Aim: to discuss the core ideas of AI and its apply to DR, as well as to evaluate the currently faced issues and the future of ophthalmology. Methods: In this review, English studies from common databases such as Pubmed/MEDLINE, Google Scholar, Web of Science, Scopus, and the Cochrane Library with the keywords "Machine Learning," "Artificial Intelligence," "Deep Learning," combined with keywords, involving "diabetic retinopathy" were involved. The end date for this review is April 2022. Scientific novelty: This paper illustrates the core AI concepts and their application in diabetic retinopathy. The current ophthalmology issues and future opportunities, offering undiscovered knowledge in this field are also analysed. It will raise community knowledge of employing AI and reveal new capabilities in the analysis of ocular disorders to present the fundamental idea of AI regarding its therapeutic applications. Conclusion: Medical professionals can make quick and precise decisions using AI technologies in orded to analyse massive volumes of data, such as physiological imaging and clinical presentations. It is believed that over time, AI systems will become more precise and successful at predicting the onset and course of DR.
背景:人工智能(AI)，通常被称为机器智能，是一个让机器人像人一样思考的科学领域。导致视力损害和失明的最常见疾病，如年龄相关性黄斑变性(ARMD)、白内障、青光眼和糖尿病性视网膜病变(DR)，最近已经成为基于深度学习的人工智能筛查和预测模型的研究对象。目的:探讨人工智能的核心思想及其在DR中的应用，评估眼科学目前面临的问题和未来。方法:本综述纳入Pubmed/MEDLINE、Google Scholar、Web of Science、Scopus、Cochrane Library等常用数据库中以“Machine Learning”、“Artificial Intelligence”、“Deep Learning”为关键词并结合“diabetic retinopathy”的英文研究。本次审查的结束日期是2022年4月。新颖性:本文阐述了人工智能的核心概念及其在糖尿病视网膜病变中的应用。目前的眼科问题和未来的机会，提供未被发现的知识，在这一领域也进行了分析。它将提高社会对使用人工智能的认识，并揭示在眼部疾病分析方面的新能力，以介绍人工智能在治疗应用方面的基本思想。结论:医疗专业人员可以使用人工智能技术做出快速准确的决策，以便分析大量数据，如生理成像和临床表现。人们相信，随着时间的推移，人工智能系统将在预测DR的发病和病程方面变得更加精确和成功。
{"title":"An overview of artificial intelligence use in diabetic retinopathy treatment: a narrative review","authors":"","doi":"10.57125/fem.2023.03.30.01","DOIUrl":"https://doi.org/10.57125/fem.2023.03.30.01","url":null,"abstract":"Background: Artificial intelligence (AI), usually called machine intelligence, is a scientific field that allows robots thinking like people. The most common diseases that cause visual impairment and blindness, such as age-related macular degeneration (ARMD), cataract, glaucoma, and diabetic retinopathy (DR), have recently been subject to deep learning-based on AI screening and prediction models.\u0000\u0000Aim: to discuss the core ideas of AI and its apply to DR, as well as to evaluate the currently faced issues and the future of ophthalmology.\u0000\u0000Methods: In this review, English studies from common databases such as Pubmed/MEDLINE, Google Scholar, Web of Science, Scopus, and the Cochrane Library with the keywords \"Machine Learning,\" \"Artificial Intelligence,\" \"Deep Learning,\" combined with keywords, involving \"diabetic retinopathy\" were involved. The end date for this review is April 2022.\u0000\u0000Scientific novelty: This paper illustrates the core AI concepts and their application in diabetic retinopathy. The current ophthalmology issues and future opportunities, offering undiscovered knowledge in this field are also analysed. It will raise community knowledge of employing AI and reveal new capabilities in the analysis of ocular disorders to present the fundamental idea of AI regarding its therapeutic applications.\u0000\u0000Conclusion: Medical professionals can make quick and precise decisions using AI technologies in orded to analyse massive volumes of data, such as physiological imaging and clinical presentations. It is believed that over time, AI systems will become more precise and successful at predicting the onset and course of DR.","PeriodicalId":327978,"journal":{"name":"Futurity Medicine","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114351255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-30DOI: 10.57125/fem.2023.03.30.02
Aims: By addressing these research issues and examining the findings of the pertinent studies, this systematic review aims to provide a thorough understanding of the changes in physical and mental health that are related with aging as well as the significant factors that contribute to these changes. This evaluation will also look into potential new treatments and technological advancements that could improve elderly people's health. The results of this work will offer crucial new perspectives on aging research and therapeutic practice in the future. Methodology: "Aging", "physical health", "mental health", "wellbeing", "lifestyle interventions", "age-related health problems", "literature evaluation", "future perspectives", "key factors", "potential new interventions", and "health outcomes" were used to search Medline, pubmed, and Google Scholar. Successful search. Data analysis began with selecting relevant details. Second, the data was compiled into a table, followed by study conclusions. After reviewing each article, the overarching idea that best proves the study issue's relevance was chosen. Results: The literature display includes several physiological and physical effects of aging and research and reference information. Aging affects skin, hair, nails, vision, digestion, bone density, muscle flexibility, and heart disease risk. Aging causes anxiety, memory loss, and executive dysfunction Scientific Novelty: Potentially effective innovative measures to enhance senior citizens' health a study of the key elements influencing how physical and mental health vary as people age Conclusion: The systematic review gave a thorough grasp of the alterations in physical and mental health brought on by aging, as well as the main causes of these alterations. The review also uncovered potential novel therapeutic approaches and scientific developments that might enhance the health of senior citizens. This work emphasizes the necessity of ongoing study and therapeutic application to improve older individuals' quality of life.
{"title":"Change in physical and mental health due to aging: future perspective","authors":"","doi":"10.57125/fem.2023.03.30.02","DOIUrl":"https://doi.org/10.57125/fem.2023.03.30.02","url":null,"abstract":"Aims: By addressing these research issues and examining the findings of the pertinent studies, this systematic review aims to provide a thorough understanding of the changes in physical and mental health that are related with aging as well as the significant factors that contribute to these changes. This evaluation will also look into potential new treatments and technological advancements that could improve elderly people's health. The results of this work will offer crucial new perspectives on aging research and therapeutic practice in the future.\u0000\u0000Methodology: \"Aging\", \"physical health\", \"mental health\", \"wellbeing\", \"lifestyle interventions\", \"age-related health problems\", \"literature evaluation\", \"future perspectives\", \"key factors\", \"potential new interventions\", and \"health outcomes\" were used to search Medline, pubmed, and Google Scholar. Successful search. Data analysis began with selecting relevant details. Second, the data was compiled into a table, followed by study conclusions. After reviewing each article, the overarching idea that best proves the study issue's relevance was chosen.\u0000\u0000Results: The literature display includes several physiological and physical effects of aging and research and reference information. Aging affects skin, hair, nails, vision, digestion, bone density, muscle flexibility, and heart disease risk. Aging causes anxiety, memory loss, and executive dysfunction\u0000\u0000Scientific Novelty: Potentially effective innovative measures to enhance senior citizens' health a study of the key elements influencing how physical and mental health vary as people age\u0000\u0000Conclusion: The systematic review gave a thorough grasp of the alterations in physical and mental health brought on by aging, as well as the main causes of these alterations. The review also uncovered potential novel therapeutic approaches and scientific developments that might enhance the health of senior citizens. This work emphasizes the necessity of ongoing study and therapeutic application to improve older individuals' quality of life.","PeriodicalId":327978,"journal":{"name":"Futurity Medicine","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132435442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-30DOI: 10.57125/fem.2023.03.30.05
Yuliia Tyravska
This article focused on peculiarities of carrying out pre-vaccination diagnostics in Ukraine in order to determine the organism adaptability. Aims: The aims of this study are to investigate the peculiarities of performing pre-vaccination diagnostics in Ukraine to ascertain the adaptability of the organism. Methodology: A descriptive cross-sectional study design was used. Secondary data was utilised and analysed. Descriptive statistics obtained and utilised Results: showed that Ukraine has over 4,000 registered microbiological laboratories, but only 2 are allowed to work with microorganisms of the first pathogenic group, 402 with the second, and all others with the third and fourth. The relevant information indicates that there are no BSL-4-compliant laboratories in Ukraine. The barriers and facilitators are such as organisational, logistical, and resource-related challenges, as well as factors that promote or delay the use of diagnostic tests in the vaccination process. In 2021, 88.5% of individuals received the first dose of the measles vaccine, while in 2020 and 2019 the coverage rates were 84.9% and 93.2%, respectively. Similarly, for the second dose of the measles vaccine, the coverage rates were 85.9%, 81.9%, and 91.7% in 2021, 2020, and 2019, respectively. Among the reasons, the desire to protect oneself (63.6%) and to others (12.5%) were the most frequent justifications for vaccination; 12.8% of respondents chose to be vaccinated for employment-related reasons. As the study found among other reasons there was the lack of awareness and knowledge about the importance of pre-vaccination diagnostics among healthcare providers and the general public, a significant barrier to compliance with national and international guidelines. Scientific Novelty: Pre-vaccination diagnostic peculiarities Conclusion: The research findings suggest that there may be peculiarities in the implementation of pre-vaccination diagnostics in Ukraine, with potential challenges related to adherence to established guidelines, stakeholder perspectives, and organisational factors.
{"title":"Peculiarities of carrying out pre-vaccination diagnostics in Ukraine in order to determine the organism adaptability","authors":"Yuliia Tyravska","doi":"10.57125/fem.2023.03.30.05","DOIUrl":"https://doi.org/10.57125/fem.2023.03.30.05","url":null,"abstract":"This article focused on peculiarities of carrying out pre-vaccination diagnostics in Ukraine in order to determine the organism adaptability.\u0000\u0000Aims: The aims of this study are to investigate the peculiarities of performing pre-vaccination diagnostics in Ukraine to ascertain the adaptability of the organism.\u0000\u0000Methodology: A descriptive cross-sectional study design was used. Secondary data was utilised and analysed. Descriptive statistics obtained and utilised\u0000\u0000Results: showed that Ukraine has over 4,000 registered microbiological laboratories, but only 2 are allowed to work with microorganisms of the first pathogenic group, 402 with the second, and all others with the third and fourth. The relevant information indicates that there are no BSL-4-compliant laboratories in Ukraine. The barriers and facilitators are such as organisational, logistical, and resource-related challenges, as well as factors that promote or delay the use of diagnostic tests in the vaccination process. In 2021, 88.5% of individuals received the first dose of the measles vaccine, while in 2020 and 2019 the coverage rates were 84.9% and 93.2%, respectively. Similarly, for the second dose of the measles vaccine, the coverage rates were 85.9%, 81.9%, and 91.7% in 2021, 2020, and 2019, respectively. Among the reasons, the desire to protect oneself (63.6%) and to others (12.5%) were the most frequent justifications for vaccination; 12.8% of respondents chose to be vaccinated for employment-related reasons. As the study found among other reasons there was the lack of awareness and knowledge about the importance of pre-vaccination diagnostics among healthcare providers and the general public, a significant barrier to compliance with national and international guidelines.\u0000\u0000Scientific Novelty: Pre-vaccination diagnostic peculiarities\u0000\u0000Conclusion: The research findings suggest that there may be peculiarities in the implementation of pre-vaccination diagnostics in Ukraine, with potential challenges related to adherence to established guidelines, stakeholder perspectives, and organisational factors.","PeriodicalId":327978,"journal":{"name":"Futurity Medicine","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126987690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.57125/fem.2022.12.30.05
This article focuses on “Ukrainian paediatrics of the future: current problems and prospects for improvement. Aims: objectives of the research study are to identify the current problems and challenges facing paediatric healthcare in Ukraine, including issues related to healthcare professionals, infrastructure, vaccination coverage, healthcare spending and public awareness of paediatric health and prevention; areas for improvement after analyses of previous initiatives; potential for future improvements in paediatric healthcare in Ukraine, including prospects related to national vaccination programs, telemedicine and digital health, medical research, the patient-centered care, medical education and training, improved healthcare infrastructure, and public-private partnerships. Study design: Descriptive cross-sectional study Place and Duration of Study: The majority of the studies were conducted on patients, professionals’ healthcare establishment and policy maker stakeholders in the Ukraine. Methodology: In order to collect secondary data a questionnaire was used. Results: Ukraine has just 665 hospital beds per 100,000 residents in 2019 compared to 417 doctors per 100,000 in 2000. The pace of replacement for most medical equipment is sluggish. Since 2019, the rates of infant, under-five, and neonatal death have been mostly steady. The rates of BCG and measles vaccination coverage have fluctuated, although they have typically gone down. The biggest problem with paediatric healthcare in Ukraine is a lack of money, which leads to a dearth of medical personnel, supplies, and equipment, as well as a high incidence of diseases that may be prevented because of a lack of public awareness of paediatric health. Conclusion: Paediatrics faces challenges, including inadequate healthcare infrastructure and a high infant and child mortality rate. Prospects for improvement, such as the development of telemedicine and e-health services, improving maternal and child healthcare services, and increasing investment in research and development. By addressing these challenges and investing in these prospects, the country can significantly improve the health and wellbeing of its children.
{"title":"Ukrainian paediatrics of the future: current problems and prospects for improvement","authors":"","doi":"10.57125/fem.2022.12.30.05","DOIUrl":"https://doi.org/10.57125/fem.2022.12.30.05","url":null,"abstract":"This article focuses on “Ukrainian paediatrics of the future: current problems and prospects for improvement.\u0000\u0000Aims: objectives of the research study are to identify the current problems and challenges facing paediatric healthcare in Ukraine, including issues related to healthcare professionals, infrastructure, vaccination coverage, healthcare spending and public awareness of paediatric health and prevention; areas for improvement after analyses of previous initiatives; potential for future improvements in paediatric healthcare in Ukraine, including prospects related to national vaccination programs, telemedicine and digital health, medical research, the patient-centered care, medical education and training, improved healthcare infrastructure, and public-private partnerships.\u0000\u0000Study design: Descriptive cross-sectional study\u0000\u0000Place and Duration of Study: The majority of the studies were conducted on patients, professionals’ healthcare establishment and policy maker stakeholders in the Ukraine.\u0000\u0000Methodology: In order to collect secondary data a questionnaire was used.\u0000\u0000Results: Ukraine has just 665 hospital beds per 100,000 residents in 2019 compared to 417 doctors per 100,000 in 2000. The pace of replacement for most medical equipment is sluggish. Since 2019, the rates of infant, under-five, and neonatal death have been mostly steady. The rates of BCG and measles vaccination coverage have fluctuated, although they have typically gone down. The biggest problem with paediatric healthcare in Ukraine is a lack of money, which leads to a dearth of medical personnel, supplies, and equipment, as well as a high incidence of diseases that may be prevented because of a lack of public awareness of paediatric health.\u0000\u0000Conclusion: Paediatrics faces challenges, including inadequate healthcare infrastructure and a high infant and child mortality rate. Prospects for improvement, such as the development of telemedicine and e-health services, improving maternal and child healthcare services, and increasing investment in research and development. By addressing these challenges and investing in these prospects, the country can significantly improve the health and wellbeing of its children.","PeriodicalId":327978,"journal":{"name":"Futurity Medicine","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127555899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.57125/fem.2022.12.30.03
Background: The main cause of death and disease on a global scale is high blood pressure, making it a critical issue for public health and a major public health concern. Objective: This review will identify the available literature and conduct a study to determine the factors which are significantly connected with hypertension based cognitive impairment among the Pakistani population. Methodology: Data was collected to evaluate the ramifications of this condition. The most significant element in hypertension-related cognitive impairment is the presence of risk factors, including socio-demographic factors, lifestyle hazards, and disease-based risks. Results: Observational studies imply that therapy with antihypertensives is related to decreased instances of cognitive impairment. Conclusion: There is a need for additional research to investigate these elements more in-depth and to compile global evidence on the subject.
{"title":"Cognitive impairment in arterial hypertension in Pakistan","authors":"","doi":"10.57125/fem.2022.12.30.03","DOIUrl":"https://doi.org/10.57125/fem.2022.12.30.03","url":null,"abstract":"Background: The main cause of death and disease on a global scale is high blood pressure, making it a critical issue for public health and a major public health concern.\u0000\u0000Objective: This review will identify the available literature and conduct a study to determine the factors which are significantly connected with hypertension based cognitive impairment among the Pakistani population.\u0000\u0000Methodology: Data was collected to evaluate the ramifications of this condition. The most significant element in hypertension-related cognitive impairment is the presence of risk factors, including socio-demographic factors, lifestyle hazards, and disease-based risks.\u0000\u0000Results: Observational studies imply that therapy with antihypertensives is related to decreased instances of cognitive impairment. \u0000\u0000Conclusion: There is a need for additional research to investigate these elements more in-depth and to compile global evidence on the subject.","PeriodicalId":327978,"journal":{"name":"Futurity Medicine","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128005543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.57125/fem.2022.12.30.02
Aims: The treatment of an acute renal failure has not received much research in Kazakhstan, whether focusing on adults or children. As a result, there is a lack of awareness about the condition of the field's knowledge as well as its challenges and prospects. Thus the goal is to identify and assess the studies that are currently accessible concerning the treatment of acute kidney failure in newborns or infants in the context of Kazakhstan experience. Study design: Literature review Methodology: MEDLINE, Cochrane Reviews, and Pedro were among the databases used to conduct the literature search. The conjunctions "AND" and "OR" were used with certain keywords. The articles' time range was restricted between 2018 and 2022 in order to only present the most recent facts. Papers discussing acute renal failure in infants only in Kazakhstan were included in the inclusion criteria. Results: Regarding the treatment of AKI in neonates in Kazakhstan, there are incredibly few available studies. The majority of trials involved individuals who were older. ESRD was more widely covered in conjunction with dialysis than AKI. Women are more prone to experience AKI turning into full-blown CKD. Conclusion: To learn more about the state of acute renal failure in neonates in Kazakhstan, more field study is required. The frequency and prevalence of placing new-borns on dialysis should be updated and made publicly accessible. It is important to emphasise the causes and risk factors of AKI in babies of Kazakh ancestry in order to comprehend current trends. Scientific Novelty: This is the first study that attempts to cover the status of pediatric acute renal failure management within Kazakhstan. It will serve as a starting point for prospective research on pediatric illnesses within the country, so as to understand where the health sector of Kazakhstan stands on the global stage.
{"title":"Acute renal failure in newborns in the practice of a pediatrician of the future","authors":"","doi":"10.57125/fem.2022.12.30.02","DOIUrl":"https://doi.org/10.57125/fem.2022.12.30.02","url":null,"abstract":"Aims: The treatment of an acute renal failure has not received much research in Kazakhstan, whether focusing on adults or children. As a result, there is a lack of awareness about the condition of the field's knowledge as well as its challenges and prospects. Thus the goal is to identify and assess the studies that are currently accessible concerning the treatment of acute kidney failure in newborns or infants in the context of Kazakhstan experience.\u0000\u0000Study design: Literature review\u0000\u0000Methodology: MEDLINE, Cochrane Reviews, and Pedro were among the databases used to conduct the literature search. The conjunctions \"AND\" and \"OR\" were used with certain keywords. The articles' time range was restricted between 2018 and 2022 in order to only present the most recent facts. Papers discussing acute renal failure in infants only in Kazakhstan were included in the inclusion criteria.\u0000\u0000Results: Regarding the treatment of AKI in neonates in Kazakhstan, there are incredibly few available studies. The majority of trials involved individuals who were older. ESRD was more widely covered in conjunction with dialysis than AKI. Women are more prone to experience AKI turning into full-blown CKD.\u0000\u0000Conclusion: To learn more about the state of acute renal failure in neonates in Kazakhstan, more field study is required. The frequency and prevalence of placing new-borns on dialysis should be updated and made publicly accessible. It is important to emphasise the causes and risk factors of AKI in babies of Kazakh ancestry in order to comprehend current trends.\u0000\u0000Scientific Novelty: This is the first study that attempts to cover the status of pediatric acute renal failure management within Kazakhstan. It will serve as a starting point for prospective research on pediatric illnesses within the country, so as to understand where the health sector of Kazakhstan stands on the global stage.","PeriodicalId":327978,"journal":{"name":"Futurity Medicine","volume":"209 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134236594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.57125/fem.2022.12.30.01
Petro Bodnar
This article focused on “Diagnostics of hemostasiological indicators of blood in patients with cervical cancer: standards, innovative models of the future (Ukraine)”. Aims: The aims of this study are to investigate the current standards, the innovative models, prognostic and predictive value of hemostasiological indicators of blood in patients with cervical cancer and identifications of potential gaps and opportunities in the current standards and innovative models for hemostasiological assessment. Methodology: A descriptive cross-sectional study design was evaluated. Secondary data were collected. Descriptive statistics were obtained and utilised. Results: The result showed that in 2020, Ukraine had 20.3 new cervical cancer cases per 100,000 women, regardless of age. Age-standardised cervical cancer incidence was 14.3 per 100,000 women. In 2020, Ukraine's lifetime cervical cancer risk was 1.4%. It illustrates cervical cancer risk. Prothrombin Time is 11–14 seconds, Activated Partial Thromboplastin Time is 25–35 seconds, fibrinogen is 200–400 mg/dL, and platelet counts are 150,000–450,000/L. Thromboelastography is a viscoelastic test that dynamically assesses blood clot formation, strength, and lysis. This test helps doctors assess cervical cancer patients' haemostatic profile and thrombotic risk and establish thromboprophylaxis regimens. In advanced cervical cancer patients, prothrombin time, APTT, fibrinogen, D-dimer, and platelet count predict thrombotic events and poor prognosis. These signs extend VTE risk. Potential gaps or opportunities include a lack of established practices, few complicated hemostasiological tests, little research, lack of knowledge and teaching, and difficulties with monitoring and follow-up, especially in resource-poor areas. Standardising techniques, expanding access to cutting-edge hemostasiological tests, and remote monitoring, and running education and awareness campaigns are future potentials for research and development. Scientific Novelty: cutting-edge hemostasiological tests in cervical cancer. Conclusion: In conclusion, resolving global cervical cancer mortality disparities needs healthcare, cancer prevention, screening, awareness, socioeconomic variables, and creative hemostasiological evaluation models. Better care, thromboprophylaxis, and collaboration can improve cervical cancer outcomes worldwide.
{"title":"Diagnostics of hemostasiological indicators of blood in patients with cervical cancer: standards, innovative models of the future (Ukraine)","authors":"Petro Bodnar","doi":"10.57125/fem.2022.12.30.01","DOIUrl":"https://doi.org/10.57125/fem.2022.12.30.01","url":null,"abstract":"This article focused on “Diagnostics of hemostasiological indicators of blood in patients with cervical cancer: standards, innovative models of the future (Ukraine)”.\u0000\u0000Aims: The aims of this study are to investigate the current standards, the innovative models, prognostic and predictive value of hemostasiological indicators of blood in patients with cervical cancer and identifications of potential gaps and opportunities in the current standards and innovative models for hemostasiological assessment.\u0000\u0000Methodology: A descriptive cross-sectional study design was evaluated. Secondary data were collected. Descriptive statistics were obtained and utilised.\u0000\u0000Results: The result showed that in 2020, Ukraine had 20.3 new cervical cancer cases per 100,000 women, regardless of age. Age-standardised cervical cancer incidence was 14.3 per 100,000 women. In 2020, Ukraine's lifetime cervical cancer risk was 1.4%. It illustrates cervical cancer risk. Prothrombin Time is 11–14 seconds, Activated Partial Thromboplastin Time is 25–35 seconds, fibrinogen is 200–400 mg/dL, and platelet counts are 150,000–450,000/L. Thromboelastography is a viscoelastic test that dynamically assesses blood clot formation, strength, and lysis. This test helps doctors assess cervical cancer patients' haemostatic profile and thrombotic risk and establish thromboprophylaxis regimens. In advanced cervical cancer patients, prothrombin time, APTT, fibrinogen, D-dimer, and platelet count predict thrombotic events and poor prognosis. These signs extend VTE risk. Potential gaps or opportunities include a lack of established practices, few complicated hemostasiological tests, little research, lack of knowledge and teaching, and difficulties with monitoring and follow-up, especially in resource-poor areas. Standardising techniques, expanding access to cutting-edge hemostasiological tests, and remote monitoring, and running education and awareness campaigns are future potentials for research and development.\u0000\u0000Scientific Novelty: cutting-edge hemostasiological tests in cervical cancer.\u0000\u0000Conclusion: In conclusion, resolving global cervical cancer mortality disparities needs healthcare, cancer prevention, screening, awareness, socioeconomic variables, and creative hemostasiological evaluation models. Better care, thromboprophylaxis, and collaboration can improve cervical cancer outcomes worldwide.","PeriodicalId":327978,"journal":{"name":"Futurity Medicine","volume":"152 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124240148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.57125/fem.2022.12.30.04
Background: Children with congenital heart disease undergoing complicated pediatric cardiac surgery with cardiopulmonary bypass (CPB) experience considerable post-operative mortality and morbidity due to post-operative bleeding. An impairment in the blood clotting system primarily contributes to excessive bleeding in children following heart surgery. Aim: to assess the different methods for the treatment of pediatric patients with post-coagulopathy cardiac surgery. Methods: Pubmed, Web of Science, Scopus, Embase, SpringerLink, and the Cochrane Library in order to find various articles concerning this topic were searched. The search strategy; (cardiac surgery) AND (pediatric) AND (coagulopathy) AND (post-operative) was used. The investigation ended in April 2022. Scientific novelty: Post-coagulopathy cardiac surgery is a relatively new medical field that has seen tremendous advances in the past decade. It involves the use of specialised techniques to reduce the risk of bleeding during and after cardiac surgery. This includes the use of anticoagulants, thrombolytics, and other medications to reduce clotting and improve outcomes. In addition, newer technologies such as robotic-assisted surgery have been developed to improve precision and accuracy during cardiac procedures. Therefore, this review aims to address the tactics of managing children-patients with post-coagulopathy cardiac surgery Conclusion: The management of children-patients with post-coagulopathy cardiac surgery is a particularly challenging area due to their unique physiology and anatomy. As such, there is a need for novel approaches to ensure optimal outcomes for these patients. For example, research has shown that using anticoagulants in combination with thrombolytics can reduce the risk of bleeding complications following cardiac surgery in pediatric patients.
背景:先天性心脏病患儿在接受复杂的小儿心脏手术合并体外循环(CPB)时，由于术后出血而导致相当高的术后死亡率和发病率。凝血系统受损是儿童心脏手术后出血过多的主要原因。目的:探讨小儿心脏手术后凝血功能障碍的不同治疗方法。方法:检索Pubmed、Web of Science、Scopus、Embase、SpringerLink和Cochrane Library，查找与该主题相关的各种文章。搜索策略;(心脏外科)和(儿科)和(凝血功能障碍)和(术后)。调查于2022年4月结束。科学新颖性:凝血后心脏手术是一个相对较新的医学领域，在过去十年中取得了巨大的进步。它包括使用专门的技术来减少心脏手术期间和之后出血的风险。这包括使用抗凝剂、溶栓剂和其他药物来减少凝血和改善预后。此外，诸如机器人辅助手术之类的新技术已经被开发出来，以提高心脏手术的精度和准确性。因此，本综述旨在探讨治疗凝血功能障碍心脏手术后儿童患者的策略。结论:由于儿童凝血功能障碍心脏手术后儿童患者独特的生理和解剖结构，其治疗是一个特别具有挑战性的领域。因此，需要新的方法来确保这些患者的最佳结果。例如，研究表明，抗凝剂与溶栓剂联合使用可以降低儿科患者心脏手术后出血并发症的风险。
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Pub Date : 2022-09-30DOI: 10.57125/fem.2022.09.30.02
Adilet Kusainov
Background: Pathology of the aorta includes aortic aneurysms, coarctation, dissection, atherosclerotic disease, and aortitis. The only two evidence-based treatment options for abdominal aortic repair are endovascular and open surgery. The anesthetic approach and medications may impact the outcomes of the surgical repair of the abdominal aorta and its branches. Aim: to evaluate the use of various analgesic regimens and local, regional, or general anesthesia in "optimising" surgical outcomes in patients undergoing surgical repair of the abdominal aorta and its branches. Methods: In this review, English studies from common databases such as Pubmed/MEDLINE, Google Scholar, Web of Science, Scopus, and the Cochrane Library with the keywords "Abdominal aorta," "operations," "aortic branches," combined with keywords, involving " anesthesia were involved." The end date for this review was November 2022. Scientific novelty: Recent scientific studies have focused on the use of advanced monitoring technologies such as cerebral oximetry and microdialysis to improve the safety and efficacy of anesthesia management in aortic surgery. These technologies provide more accurate and real-time information about cerebral perfusion and metabolism, allowing the anesthesiologist to identify and manage potential complications such as cerebral ischemia more effectively. Additionally, the use of pharmacological agents such as dexmedetomidine and remifentanil has been shown to reduce the risk of postoperative delirium and cognitive dysfunction, further improving patient outcomes. Conclusion: Aortic surgery is a complex and high-risk procedure that requires careful management of anesthesia to ensure patient safety and optimal outcomes. With ongoing advances in anesthesia techniques and monitoring technologies, there is reason to be optimistic about the future of aortic surgery and the prospects for improved patient outcomes. The anesthesiologist plays a critical role in this process, working closely with the surgical team to provide safe and effective anesthesia throughout the procedure and ensuring that the patient receives appropriate pain management and other supportive care in the postoperative period
背景:主动脉的病理包括主动脉瘤、缩窄、夹层、动脉粥样硬化性疾病和主动脉炎。腹主动脉修复仅有的两种循证治疗选择是血管内手术和开放手术。麻醉方法和药物可能影响手术修复腹主动脉及其分支的结果。目的:评价不同镇痛方案和局部、区域或全身麻醉在腹主动脉及其分支手术修复患者的“优化”手术效果中的应用。方法:在本综述中，检索Pubmed/MEDLINE、Google Scholar、Web of Science、Scopus、Cochrane Library等常用数据库中以“腹主动脉”、“手术”、“主动脉分支”为关键词并结合“涉及麻醉”的英文研究。此次审查的结束日期是2022年11月。科学新颖性:最近的科学研究集中在使用先进的监测技术，如脑血氧仪和微透析，以提高麻醉管理在主动脉手术中的安全性和有效性。这些技术提供了更准确和实时的脑灌注和代谢信息，使麻醉师能够更有效地识别和管理潜在的并发症，如脑缺血。此外，使用右美托咪定和瑞芬太尼等药物已被证明可以降低术后谵妄和认知功能障碍的风险，进一步改善患者的预后。结论:主动脉手术是一项复杂且高风险的手术，需要仔细的麻醉管理，以确保患者的安全和最佳结果。随着麻醉技术和监测技术的不断进步，我们有理由对主动脉手术的未来和改善患者预后的前景持乐观态度。麻醉师在这一过程中起着至关重要的作用，与手术团队密切合作，在整个手术过程中提供安全有效的麻醉，并确保患者在术后接受适当的疼痛管理和其他支持性护理
{"title":"Optimising anesthesia support during operations on the abdominal aorta and its branches","authors":"Adilet Kusainov","doi":"10.57125/fem.2022.09.30.02","DOIUrl":"https://doi.org/10.57125/fem.2022.09.30.02","url":null,"abstract":"Background: Pathology of the aorta includes aortic aneurysms, coarctation, dissection, atherosclerotic disease, and aortitis. The only two evidence-based treatment options for abdominal aortic repair are endovascular and open surgery. The anesthetic approach and medications may impact the outcomes of the surgical repair of the abdominal aorta and its branches.\u0000\u0000Aim: to evaluate the use of various analgesic regimens and local, regional, or general anesthesia in \"optimising\" surgical outcomes in patients undergoing surgical repair of the abdominal aorta and its branches.\u0000\u0000Methods: In this review, English studies from common databases such as Pubmed/MEDLINE, Google Scholar, Web of Science, Scopus, and the Cochrane Library with the keywords \"Abdominal aorta,\" \"operations,\" \"aortic branches,\" combined with keywords, involving \" anesthesia were involved.\" The end date for this review was November 2022.\u0000\u0000Scientific novelty: Recent scientific studies have focused on the use of advanced monitoring technologies such as cerebral oximetry and microdialysis to improve the safety and efficacy of anesthesia management in aortic surgery. These technologies provide more accurate and real-time information about cerebral perfusion and metabolism, allowing the anesthesiologist to identify and manage potential complications such as cerebral ischemia more effectively. Additionally, the use of pharmacological agents such as dexmedetomidine and remifentanil has been shown to reduce the risk of postoperative delirium and cognitive dysfunction, further improving patient outcomes.\u0000\u0000Conclusion: Aortic surgery is a complex and high-risk procedure that requires careful management of anesthesia to ensure patient safety and optimal outcomes. With ongoing advances in anesthesia techniques and monitoring technologies, there is reason to be optimistic about the future of aortic surgery and the prospects for improved patient outcomes. The anesthesiologist plays a critical role in this process, working closely with the surgical team to provide safe and effective anesthesia throughout the procedure and ensuring that the patient receives appropriate pain management and other supportive care in the postoperative period","PeriodicalId":327978,"journal":{"name":"Futurity Medicine","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130135902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-30DOI: 10.57125/fem.2022.09.30.04
Victoriia Ilina-Stohniienko, Milan Malets
This article focuses on “Regarding the modernisation of medical care system for victims of armed conflicts (Ukrainian experience)”. Aims: The purpose of the study concerning the modernisation of medical treatment system for victims of armed conflicts is to examine the existing status, challenges and barriers for an effective medical care system, to explore innovative approaches and technologies, policy and regulatory frameworks as well as to propose strategies and highlight the ethical implications of modernising medical care for victims of armed conflict in Ukraine. Study design: Descriptive cross-sectional study. Place and Duration of Study: Most of the studies were conducted on patients, professionals’ healthcare establishment and policy maker stakeholders. Methodology: In order to collect secondary data from literature a questionnaire was used. Results: 4,094 assaults and threats against the health care system were found. Harmed 1,524 healthcare personnel. 681 health professionals died. 401 health professionals were abducted. 978 occurrences involved destroyed or damaged medical facilities. The results showed the limitations and needs of the health system, obstacles in providing and obtaining health care, collaboration with neighbouring states, sustainability and development transitions conflict related policy and its implementation. Statistics show that no communicable illnesses have replaced communicable diseases as the main causes of sickness and death. Cardiovascular disease, diabetes, cancer, chronic respiratory illnesses, and mental disorders account for up to 84% of all morbidity. Antibiotic resistance has also increased as a result of the fight. They developed telemedicine, developed mobile medical facilities, and provided counselling and rehabilitation services. Academic s may help improve data quality and analysis alongside governmental and humanitarian players in Ukraine. Conclusion: To protect healthcare in places afflicted by violence, coordinated actions across states, international organisations, and humanitarian groups are essential. The accessibility guarantee and security of health services for everyone, proactive measures, respect to international law, and ongoing healthcare expenditures are required.
{"title":"Regarding the modernisation of medical care system for victims of armed conflicts (Ukrainian experience)","authors":"Victoriia Ilina-Stohniienko, Milan Malets","doi":"10.57125/fem.2022.09.30.04","DOIUrl":"https://doi.org/10.57125/fem.2022.09.30.04","url":null,"abstract":"This article focuses on “Regarding the modernisation of medical care system for victims of armed conflicts (Ukrainian experience)”.\u0000\u0000Aims: The purpose of the study concerning the modernisation of medical treatment system for victims of armed conflicts is to examine the existing status, challenges and barriers for an effective medical care system, to explore innovative approaches and technologies, policy and regulatory frameworks as well as to propose strategies and highlight the ethical implications of modernising medical care for victims of armed conflict in Ukraine.\u0000\u0000Study design: Descriptive cross-sectional study.\u0000\u0000Place and Duration of Study: Most of the studies were conducted on patients, professionals’ healthcare establishment and policy maker stakeholders.\u0000\u0000Methodology: In order to collect secondary data from literature a questionnaire was used.\u0000\u0000Results: 4,094 assaults and threats against the health care system were found. Harmed 1,524 healthcare personnel. 681 health professionals died. 401 health professionals were abducted. 978 occurrences involved destroyed or damaged medical facilities. The results showed the limitations and needs of the health system, obstacles in providing and obtaining health care, collaboration with neighbouring states, sustainability and development transitions conflict related policy and its implementation. Statistics show that no communicable illnesses have replaced communicable diseases as the main causes of sickness and death. Cardiovascular disease, diabetes, cancer, chronic respiratory illnesses, and mental disorders account for up to 84% of all morbidity. Antibiotic resistance has also increased as a result of the fight. They developed telemedicine, developed mobile medical facilities, and provided counselling and rehabilitation services. Academic s may help improve data quality and analysis alongside governmental and humanitarian players in Ukraine.\u0000\u0000Conclusion: To protect healthcare in places afflicted by violence, coordinated actions across states, international organisations, and humanitarian groups are essential. The accessibility guarantee and security of health services for everyone, proactive measures, respect to international law, and ongoing healthcare expenditures are required.","PeriodicalId":327978,"journal":{"name":"Futurity Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129648864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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