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Criteria for Diagnosis and Evaluation of Frailty Syndrome 虚弱综合征的诊断与评价标准
Pub Date : 2021-09-01 DOI: 10.36145/jhsm2021.13
Karolina Studzińska, Rafał Studnicki, Tomasz Adamczewski, R. Hansdorfer-Korzon
Abstract Frailty syndrome is defined as a progressive state of reducing the body’s physiological reserves with age and is characterized by an increased susceptibility to sudden, disproportionate deterioration in functioning, after which it is impossible to return to previous fitness and independence. The typical clinical symptoms of this syndrome include generalized weakness, decreased strength and muscle mass, deterioration of exertion tolerance, slowing of movement, loss of balance, deterioration of cognitive functions, weight loss or malnutrition. Frailty syndrome worsens the prognosis for seniors, increases the risk of reduced physical and/or mental performance, dependence on others, may cause hospitalization, lead to postoperative complications, social withdrawal, and ultimately premature death. Among the most important interventions in the prevention and treatment of frailty syndrome is regular and thoughtfully planned physical activity. The incidence of frailty syndrome increases with age – it affects from 2%–5% of respondents aged 18–34, and in people over 65, it ranges from 4%–59%. Based on research conducted in Poland, it is estimated that frailty syndrome affects 6.7% of the elderly, including 30% of people aged 75–80 and 50% of people over 80 years of age. Most often, frailty is diagnosed based on an interview and physical examination. An important issue in its identification is the lack of unambiguous diagnostic criteria for evaluating the syndrome. The most common tool for evaluating the frailty syndrome in the context of physical limitations are the criteria developed by Linda Fried, introduced and described based on the analysis of the Cardiovascular Health Study clinical trials.
衰弱综合征是一种随着年龄增长身体生理储备逐渐减少的进行性状态,其特征是机体功能突然、不成比例地恶化的易感性增加,此后不可能恢复到以前的健康和独立状态。该综合征的典型临床症状包括全身无力、力量和肌肉量下降、运动耐受性下降、运动迟缓、失去平衡、认知功能恶化、体重减轻或营养不良。虚弱综合征恶化了老年人的预后,增加了身体和/或精神表现下降、依赖他人的风险,可能导致住院,导致术后并发症、社交退缩,最终导致过早死亡。预防和治疗虚弱综合征最重要的干预措施之一是定期和精心计划的身体活动。虚弱综合征的发病率随着年龄的增长而增加,18-34岁的受访者中有2%-5%患有此病,65岁以上的人群中有4%-59%患有此病。根据在波兰进行的研究,估计虚弱综合征影响6.7%的老年人,其中包括30%的75-80岁人群和50%的80岁以上人群。大多数情况下,虚弱是通过面谈和身体检查来诊断的。在其鉴定的一个重要问题是缺乏明确的诊断标准来评估该综合征。在身体限制的情况下,评估虚弱综合征最常用的工具是琳达·弗里德(Linda Fried)制定的标准,该标准是根据心血管健康研究临床试验的分析介绍和描述的。
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引用次数: 0
Motivations for Volunteering among Future Healthcare Professionals during the COVID-19 Epidemic: A Case Study from Poland COVID-19流行期间未来医疗保健专业人员志愿服务的动机:来自波兰的案例研究
Pub Date : 2021-09-01 DOI: 10.36145/jhsm2021.15
J. Domaradzki, D. Walkowiak
Abstract Background Ever since the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) stuck health care systems in many countries have been seriously burdened. Simultaneously, thousands of medical students across Europe have volunteered to support the fight against the COVID-19 pandemic. Objectives The paper aims to analyse the motivations for the volunteering among future healthcare professionals in times of a coronavirus outbreak. Material and methods The study was conducted among 311 students of Poznan University of Medical Sciences, Poland, who answered questions regarding the reasons they became involved in voluntary service during the pandemic. Answers were used to categorize respondents’ motivations for their voluntary service in different functions. Results While four functions served by volunteering during the coronavirus pandemic have been identified: values, enhancement, career and social, students were mainly motivated by altruistic reasons: the ideal of doing good, helping others and giving something back to the community. Moreover, many believed that as future health professionals it was their duty to engage, whatever the risk. Gender and religiosity were the key factors conditioning students’ motivations. Conclusions While volunteering has served many purposes during the coronavirus pandemic, value-based motivations were the primary force behind students’ engagement. At the same time, students’ religiosity seems the key factor that determined their motivations.
背景自SARS-CoV-2疫情爆发以来,许多国家的卫生保健系统都面临着沉重的负担。与此同时,欧洲各地数千名医学生自愿支持抗击COVID-19大流行。本文旨在分析在冠状病毒爆发时期未来医疗保健专业人员志愿服务的动机。材料和方法该研究以波兰波兹南医科大学的311名学生为对象,他们回答了有关他们在大流行期间参与志愿服务的原因的问题。回答被用来分类受访者在不同职能的志愿服务动机。结果新型冠状病毒大流行期间,大学生志愿服务具有价值观、自我提升、职业发展和社会四个功能,但大学生志愿服务的主要动机是利他主义:行善、助人、回馈社会。此外,许多人认为,作为未来的卫生专业人员,他们有责任参与其中,无论风险如何。性别和宗教信仰是影响学生学习动机的主要因素。虽然在冠状病毒大流行期间志愿服务有很多目的,但基于价值的动机是学生参与背后的主要力量。与此同时,学生的宗教信仰似乎是决定其动机的关键因素。
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引用次数: 1
Sex-determining Region Y-related (SRY) High-mobility Group Box 4 (SOX4) Immunoexpression in Colorectal Cancer as an Unappreciated Parameter for More Individual Approach in Cancer Disease – A Preliminary Study 性别决定区y相关(SRY)高迁移率组框4 (SOX4)免疫表达在结直肠癌中作为一种未被重视的参数,用于更个性化的癌症疾病治疗-一项初步研究
Pub Date : 2021-09-01 DOI: 10.36145/jhsm2021.14
Katarzyna Joanna Gąsior, Aleksandra Hincz, M. Cichoń, Paweł Kapszewicz, Elżbieta Sałacińska-Łoś, M. Orzechowska, K. Taran
Abstract Background Colorectal cancer is one of the most important problems that medicine has to face nowadays. Despite the development of new diagnostic tools and therapeutic strategies in oncology, it still takes the leading position regarding cancer related deaths, which proves the presence of undiscovered part of its biology. Therefore, is justified to search for new biomarkers to determine better colorectal cancer biology. Sexdetermining region Y-related (SRY) high-mobility group box 4 (SOX4) is currently highly investigated protein which expression was identified in many pathological processes, including malignancies with the highest mortality rates and which seems to be a promising marker related to cancer progression. Objectives The aim of the study was to evaluate SOX4 expression level in colorectal cancer cells and search for its potential relation to the established prognostic parameters for more individual approach in cancer disease. Material and methods Immunohistochemical evaluation of the SOX4 protein expression in colorectal cancer cells supported by statistical analysis of the relation to tumour stage, grade, and presence of lymph node metastases, as well as chosen histoclinical features. Results Obtain results showed for the first time complex expression of SOX4 in colorectal cancer. There were revealed differences of SOX4 immunoexpression regarding tumour grade, lymph node status, and tumour ulceration, as well as potential relation between SOX4 expression and patients’ age and sex and grade 1 histological malignancy of the tumour. Conclusions Obtained results support the role of the SOX4 in colorectal cancer biology and for the first time indicate the relation with the established prognostic factors: tumour grade and lymph node status. The findings revealed in presented studies alight SOX4 expression as a promising parameter for colorectal cancer more individual approach with prospective clinical impact.
摘要背景结直肠癌是当今医学必须面对的重要问题之一。尽管在肿瘤学中有了新的诊断工具和治疗策略,但它仍然在癌症相关死亡方面处于领先地位,这证明了其生物学中未被发现的部分的存在。因此,寻找新的生物标志物来确定更好的结直肠癌生物学是合理的。性别决定区y相关(SRY)高迁移率组框4 (SOX4)是目前高度研究的蛋白,其表达在许多病理过程中被发现,包括死亡率最高的恶性肿瘤,它似乎是一个有希望的与癌症进展相关的标志物。本研究旨在评估SOX4在结直肠癌细胞中的表达水平,并寻找其与已建立的预后参数的潜在关系,以便更个性化地治疗癌症疾病。材料与方法通过统计分析肿瘤分期、分级、有无淋巴结转移以及选择的组织临床特征,对结直肠癌细胞中SOX4蛋白表达进行免疫组化评价。结果首次获得SOX4在结直肠癌中复杂表达的结果。SOX4的免疫表达与肿瘤分级、淋巴结状态、肿瘤溃疡程度有关,与患者的年龄、性别、肿瘤的1级组织学恶性程度有关。结论获得的结果支持SOX4在结直肠癌生物学中的作用,并首次表明其与肿瘤分级和淋巴结状态等预后因素的关系。目前的研究结果表明,SOX4表达是结直肠癌的一个有希望的参数,具有前瞻性的临床影响。
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引用次数: 0
The Use of Latex Powdered Gloves in Health Care and Skin Problems on the Hands: A Pilot Study in Croatian Hospitals 在保健和手部皮肤问题中使用乳胶粉手套:克罗地亚医院的一项试点研究
Pub Date : 2021-09-01 DOI: 10.36145/jhsm2021.17
Hana Knežević Krajina, Bojana Knezevic
Abstract Background The prevalence of latex allergy in the population of healthcare workers is higher than in the general population. In the last decade, the use of powder gloves has been reduced or banned due to the risk of developing adverse effects and diseases to individuals exposed to them. Latex gloves are used on a daily basis in Croatian hospitals. Powdered latex gloves are still in everyday use in Croatia. Objectives The aim of this cross-sectional study was to do screening among healthcare professionals for hand diseases after wearing gloves, and to test a positive correlation between symptoms on the hands and work in the hospital. Subjects and methods The data were collected by the self-assessment questionnaire The Latex Allergy Screening Questionnaire. The participants were healthcare workers who regularly use latex gloves in hospitals. Results The study included 455 healthcare workers: 361 nurses, 71 physicians, and 23 other healthcare workers. The most often symptoms of dermatitis occur in workers who use gloves for more than three hours a day, with the highest frequency in the group wearing gloves between 3 and 5 hours a day. Contact dermatitis develops more significantly in the participants who wear gloves more than 5 hours a day (P=0.001). Of all participants, after latex glove use, 45.05% had various symptoms on the skin of the hand related to gloves use and 18% reported contact urticaria after contact with latex gloves. Most of them (89.8%) who suffered from various symptoms related to gloves, did not have any symptoms when they were on holiday or sick leave. Conclusion Nearly half of the participants have some problems with the skin after wearing latex gloves. Most participants have had those symptoms withdrawn when they took a sick leave or a vacation. The ban on powdered gloves should be considered as a preventive measure.
摘要背景:乳胶过敏在卫生保健工作者人群中的患病率高于一般人群。在过去十年中,粉末手套的使用已经减少或禁止,因为接触它们的人可能会产生不利影响和疾病。克罗地亚的医院每天都使用乳胶手套。在克罗地亚,粉末乳胶手套仍在日常使用。目的本横断面研究的目的是筛查医护人员戴手套后的手部疾病,并检验手部症状与医院工作之间的正相关关系。研究对象和方法采用乳胶过敏筛查问卷进行自评。参与者是经常在医院使用乳胶手套的医护人员。结果共纳入455名医护人员,其中护士361名,医生71名,其他医护人员23名。皮炎症状最常发生在每天使用手套3小时以上的工人身上,每天使用手套3至5小时的工人发病率最高。接触性皮炎在每天戴手套超过5小时的参与者中更为显著(P=0.001)。在所有参与者中,45.05%的人在使用乳胶手套后,手部皮肤出现了与使用手套有关的各种症状,18%的人在接触乳胶手套后报告了接触性荨麻疹。出现与手套有关的各种症状的人中,大部分(89.8%)在休假或病假期间没有任何症状。结论近半数受试者在佩戴乳胶手套后出现皮肤问题。大多数参与者在请病假或度假时,这些症状都消失了。禁止使用有粉手套应该被视为一种预防措施。
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引用次数: 0
The Pilot Study of C-jun and TGF-beta Immunoexpression in Relation to the Oldest Cancer Biomarkers – Tumor Histology and Proliferation Rate in Glioblastoma and Neuroblastoma Models of Cancer Disease 胶质母细胞瘤和神经母细胞瘤模型中C-jun和tgf - β免疫表达与最古老的癌症生物标志物-肿瘤组织学和增殖率相关的初步研究
Pub Date : 2021-06-01 DOI: 10.36145/jhsm2021.07
Aleksandra Hincz, Katarzyna Joanna Gąsior, M. Cichoń, Paweł Kapszewicz, Elżbieta Sałacińska-Łoś, M. Orzechowska, K. Taran
Abstract Background Prognostic factors in cancers are believed to be one of the most important discoveries in oncology. However, due to the development of integrated science they are not restricted to morphological anomalies anymore. In everyday routine the light microscope markers are systematically replaced by new ones, especially of immunohistochemical and molecular type. It leads to the question what is the relation of the oldest prognostic parameters to the basic and newly discovered pathways common for cancer disease itself. Objectives The aim of presented studies is to investigate the most modern factors involved in pathological processes in the two models of cancer disease, glioblastoma in adults and neuroblastoma in developmental age to search for potential relation with the established prognostic factors appropriately to the tumor type, including the oldest known light microscope parameters – tumor histology and proliferation rate of cancer cells. Material and methods Immunohistochemical assessment of expression of c-jun in glioblastoma and TGF-beta in neuroblastoma group in relation to chosen histoclinical features: patients’ related (age, gender) and tumor related; including all the widely excepted prognostic parameters regarding the tumor type (location, histological type (neuroblastoma, ganglioneuroblastoma, ganglioneuroma), tumor histology (favorable, unfavorable), Ki-67 index, stage. Results Variations of c-jun immunoexpression were revealed in glioblastoma as well as differences in TGF-beta expression in neuroblastoma regarding the examined histoclinical features. Furthermore, in both cancer groups the levels of the examined protein expression appeared to relate to cancer cell proliferation estimated by the established parameter – Ki67 indices. Conclusions In both models of cancer disease, glioblastoma in adults and neuroblastoma in developmental age there is a crossing of pathways of the oldest and the newest cancer disease markers. Although integrated science offers the most advanced approaches it is important to consider the old established prognostic parameters in prognostication in individual, especially doubtful cases.
摘要背景肿瘤预后因素被认为是肿瘤学中最重要的发现之一。然而,由于综合科学的发展,它们不再局限于形态异常。在日常工作中,光镜标记物被新的标记物系统地取代,特别是免疫组织化学标记物和分子标记物。这就引出了一个问题:最古老的预后参数与癌症疾病本身常见的基本和新发现的途径之间的关系是什么?目的探讨成人胶质母细胞瘤和发育年龄神经母细胞瘤两种肿瘤模型的病理过程中涉及的最现代的因素,以寻找与肿瘤类型相关的既定预后因素的潜在关系,包括已知最古老的光镜参数-肿瘤组织学和癌细胞增殖率。材料与方法免疫组化评价c-jun在胶质母细胞瘤中的表达和tgf - β在神经母细胞瘤组中的表达与选择的组织临床特征的关系:患者相关(年龄、性别)和肿瘤相关;包括所有广泛例外的预后参数,如肿瘤类型(部位、组织学类型(神经母细胞瘤、神经节神经母细胞瘤、神经节神经瘤)、肿瘤组织学(有利、不利)、Ki-67指数、分期。结果胶质母细胞瘤中c-jun免疫表达的变化以及神经母细胞瘤中tgf - β表达的差异与所检查的组织临床特征有关。此外,在两个癌症组中,检测的蛋白表达水平似乎与通过建立的参数- Ki67指数估计的癌细胞增殖有关。结论在两种癌症疾病模型中,成人胶质母细胞瘤和发育年龄的神经母细胞瘤存在最古老和最新的癌症疾病标志物通路交叉。尽管综合科学提供了最先进的方法,但重要的是在个体预测中考虑旧的既定预测参数,特别是可疑病例。
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引用次数: 0
Perception of Advertising of Tobacco Products and Warnings about the Harmfulness of Smoking by Smokers 吸烟者对烟草制品广告的认知及吸烟危害警告
Pub Date : 2021-06-01 DOI: 10.36145/jhsm2021.10
Ewa Siwińska-Beck, M. Znyk, D. Kaleta
Abstract Introduction Advertising of tobacco products contributes to the increase in the number of smokers. Also in Poland, the regulations in force prohibit advertising and promotion of tobacco products, symbols related to their use, as well as tobacco props and products imitating them. This prohibition applies to the promotion and advertising of tobacco products, including in public places, schools, health care institutions, but also on television, radio, in the press, cinemas and on billboards. The 6 effective actions of the MPOWER package of the World Health Organization, which may limit the consumption of tobacco products in society, include the elimination of marketing practices violating the ban on promotion and advertising of tobacco products, as well as warning and informing about health risks related to the use of tobacco. According to research, graphic health warnings on tobacco products are effective. They reliably reach tobacco users every time they use these products. Aim The aim of the study was to assess the perception of advertisements for tobacco products and warnings about the harmful effects of smoking by smokers. Material and methods A survey conducted in 2015. 114 smokers from Piotrków County. The research tool was a questionnaire. The Bioethics Committee of the Medical University of Lodz issued a positive opinion on the study (RNN/243/15/KE). Results During the last 30 days, smokers most often encountered information on the harmful effects of smoking on television (54%) and in newspapers or magazines (52%). Within the last 30 days, 97% of respondents saw information on the dangers of smoking on cigarette packets. 54% of smokers, under the influence of health warnings on cigarette packets, considered stopping smoking in the last 30 days. Smokers noticed forms of promotion of cigarettes: as many as 16% of respondents noticed free cigarette samples, 13% of discounted cigarettes. 36% of smokers believed that advertising and displaying tobacco products at points of sale did not affect the type of product purchased. Conclusions There is a need for interventions to alert against the dangers of smoking. Rules to ban tobacco display and smoke warning can help reduce smoking.
烟草制品的广告助长了吸烟人数的增加。同样在波兰,现行条例禁止烟草产品的广告和促销、与其使用有关的标志以及烟草道具和模仿它们的产品。这一禁令适用于烟草产品的促销和广告,包括在公共场所、学校、保健机构,但也适用于电视、广播、报刊、电影院和广告牌。世界卫生组织MPOWER一揽子计划的6项有效行动可能会限制社会对烟草制品的消费,其中包括消除违反禁止烟草制品促销和广告的营销做法,以及就与使用烟草有关的健康风险发出警告和通报。根据研究,烟草制品上的图形健康警语是有效的。每次烟草使用者使用这些产品时,它们都可靠地接触到他们。该研究的目的是评估吸烟者对烟草产品广告和吸烟有害影响警告的看法。材料与方法2015年调查。来自Piotrków县的114名吸烟者。研究工具是问卷调查。罗兹医科大学生物伦理委员会对该研究发表了积极的意见(RNN/243/15/KE)。结果在过去30天内,吸烟者最常在电视(54%)和报纸或杂志(52%)上看到有关吸烟有害影响的信息。在过去30天内,97%的受访者看到了烟盒上有关吸烟危害的信息。54%的吸烟者在烟盒健康警示的影响下,考虑在过去30天内戒烟。吸烟者注意到香烟的促销形式:多达16%的受访者注意到免费香烟样品,13%的受访者注意到打折香烟。36%的吸烟者认为,销售点的烟草产品广告和展示不会影响所购买产品的类型。结论有必要采取干预措施,提醒人们注意吸烟的危害。禁止烟草展示和烟雾警告的规定有助于减少吸烟。
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引用次数: 0
Human Resource Management in the Group of Doctors and Nurses Employed in the Tomaszów Health Centre in Tomaszów Mazowiecki 马佐维耶茨基Tomaszów保健中心Tomaszów医生和护士群体的人力资源管理
Pub Date : 2021-06-01 DOI: 10.36145/jhsm2021.08
Marta Świerczyńska, Monika Zgoła, Małgorzata Widawska, Paulina Stasiołek, A. Gawron-Skarbek
Abstract Introduction Human resource management is a key process in organisation management. Skilful management of the staff, setting the goals and motivating the employees to high-level performance of their tasks help to achieve the organisation’s goals consistently. Purposes The study was aimed to analyse the process of motivating the doctors and nurses working in the Tomaszów Health Centre and to investigate the staff’s satisfaction with the incentives used in their workplace. Materials and methods The study population covered fifty doctors and fifty nurses employed at four departments of the Tomaszów Health Centre. The study involved an analysis of the factors which motivate and demotivate the THC staff and an investigation of the incentives used towards the staff. The level of the study population (doctors and nurses) satisfaction with the methods of their motivation was also examined. Results The analysis of the results revealed that the most desired factors with the most positive impact on the staff motivation level include appreciation bonuses (40% of the respondents), good atmosphere at work (38%) and the possibility to enhance one’s qualifications (21%). The stimulus which affects the effectiveness of the staff’s performance of their duties is an orally expressed praise of the CEO/president, boss or superior (31%). The doctors and nurses in the study population do not feel satisfied with the incentive scheme used in the THC (69%). Conclusions In-cash factors play the most important role in the incentive scheme for the majority of THC’s employees. Most of the doctors and nurses working for THC do not feel satisfied with the incentives used in their workplace.
人力资源管理是组织管理的关键环节。对员工的熟练管理,设定目标和激励员工高水平地完成任务,有助于始终如一地实现组织的目标。本研究的目的是分析在Tomaszów健康中心工作的医生和护士的激励过程,并调查工作人员对其工作场所使用的激励措施的满意度。研究对象包括Tomaszów保健中心四个部门的50名医生和50名护士。这项研究分析了激励和打击THC工作人员的因素,并调查了对工作人员使用的激励措施。研究人群(医生和护士)对其动机方法的满意度水平也进行了调查。结果对结果的分析显示,对员工激励水平影响最大的最期望因素包括奖励(40%)、良好的工作氛围(38%)和提升个人资格的可能性(21%)。影响员工有效履行职责的激励因素是CEO/总裁、老板或上级的口头表扬(31%)。研究人群中的医生和护士对THC中使用的激励方案不满意(69%)。结论现金因素在绝大多数THC员工的激励方案中起着最重要的作用。大多数为THC工作的医生和护士对他们工作场所使用的激励措施感到不满意。
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引用次数: 0
Identity and Culture of Medical Schools in Poland 波兰医学院的身份和文化
Pub Date : 2021-06-01 DOI: 10.36145/jhsm2021.11
Joanna Sułkowska
Abstract A scientific school could be defined as a form of community that includes a group of scholars, researchers sharing similar ideas, and approaching specific scientific problems in the same way. The crucial characteristic of a scientific school is based on values, culture and identity of scholars represented by similar research orientation. The objective of the paper is to describe the characteristics of the organizational identity of medical science schools. The research methodology is based on a review of the literature on the subject.
科学学派可以被定义为一种社区形式,它包括一群拥有相似思想的学者、研究人员,并以相同的方式处理特定的科学问题。以相似的研究取向为代表的学者的价值观、文化和身份是科学学派的关键特征。本文的目的是描述医学院校组织认同的特征。研究方法是基于对这个主题的文献的回顾。
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引用次数: 0
Is Obesity Significantly Connected with Urogenital Disorders? – Systematic Review 肥胖与泌尿生殖系统疾病有显著关系吗?-系统检讨
Pub Date : 2021-06-01 DOI: 10.36145/jhsm2021.12
A. Wijata, Joanna Osiak, K. Kędziora–Kornatowska
Abstract Background Obesity was declared an epidemic of the 21st century by WHO. Currently, as many as 39% of adults in the world are overweight and 13% are obese. The number of obese people in the world has tripled since 1975. As is well known, excessive abnormal body weight has a significant impact on the functioning of the entire body. It is very common to emphasize education on cardiovascular implications related to obesity matter – however, overweight and obese patients may also be a group particularly vulnerable to problems related to the urogenital system. Objectives The aim of the study is to draw attention and discuss the problems related to the above-mentioned system, to which this group of patients is exposed more frequently than patients with normal body weight. They include dysfunctions that do not pose a threat to the patient’s life, but significantly reduce the quality of life, such as urinary incontinence and impotence, and severe and even life-threatening diseases such as chronic kidney disease or cancer. Material and methods Based on numerous data available on this subject and collected from various research centers using Google Scholar and Pub-Med, the most recent and the most important information on this subject has been summarized. To better present and understand the problem, the mechanisms were also discussed, so that the work is a complete analysis, particularly useful in the current obesity epidemic. Results Obesity is associated with an increased risk of many diseases of the urogenital system. It causes a worse prognosis and makes treatment less effective. Treatment of obesity should be the first line of treatment of the discussed diseases of the genitourinary system. Conclusions Obesity is a serious and growing problem all over the world. It has an impact on the epidemiology of many diseases of the urogenital system, therefore paying special attention to its prevention and treatment seems to be one of the most important foundations for the prevention and treatment of dysfunctions of the genitourinary system.
世界卫生组织宣布肥胖症为21世纪的一种流行病。目前,世界上多达39%的成年人超重,13%的成年人肥胖。自1975年以来,世界上肥胖人口的数量增加了两倍。众所周知,体重过度异常会对整个身体的功能产生重大影响。强调与肥胖问题相关的心血管影响的教育是很常见的——然而,超重和肥胖患者也可能是一个特别容易受到泌尿生殖系统相关问题影响的群体。本研究的目的是引起人们对上述系统相关问题的关注和讨论,这组患者比正常体重的患者更频繁地暴露于上述系统。它们包括对患者生命不构成威胁但显著降低生活质量的功能障碍,如尿失禁和阳痿,以及严重甚至危及生命的疾病,如慢性肾病或癌症。材料和方法基于这一主题的大量可用数据,并使用Google Scholar和Pub-Med从各个研究中心收集,总结了关于这一主题的最新和最重要的信息。为了更好地呈现和理解问题,还讨论了机制,使工作是一个完整的分析,在当前的肥胖流行特别有用。结果肥胖与泌尿生殖系统多种疾病的发病风险增加有关。它会导致更糟糕的预后,使治疗效果降低。治疗肥胖应是治疗泌尿生殖系统疾病的第一线。结论肥胖是一个日益严重的世界性问题。它影响着泌尿生殖系统许多疾病的流行病学,因此,特别重视其预防和治疗似乎是预防和治疗泌尿生殖系统功能障碍的最重要的基础之一。
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引用次数: 0
Smoking Tobacco – a Risk Factor for Breast Cancer 吸烟是乳腺癌的一个危险因素
Pub Date : 2021-06-01 DOI: 10.36145/jhsm2021.09
Marta Szkiela, E. Kusideł, Ewa Siwińska-Beck, T. Makowiec-Dąbrowska
Abstract Introduction In 2009, the International Agency for Research on Cancer (IARC) stated that there was “limited evidence of a cause and effect relationship between an increased risk of breast cancer and smoking”. Environmental tobacco smoke is known to cause cancer by exerting both carcinogenic and genotoxic effects. The aim of the study was to assess the relationship between smoking (active and passive) and breast cancer risk. Material and methods The case/control study was conducted from 2015– –2019 in the Lodz region. The case group included 384 women with breast cancer; the control group included 298 healthy women. The research tool was an anonymous questionnaire. Results In the group of 682 respondents, 63% have ever smoked cigarettes (65.4%/60.1% in the case/control group respectively), 22.1% were current smokers, 67% were exposed to passive smoking. In the majority of cases, women were exposed to smoking by the husband (86%), the father (55.5%) or both (43.2%). Breast cancer risk is 253–271% higher for smokers (current – past) in comparison to the group of non-smokers, never exposed to passive smoking. The risk for passive smokers is 139% higher than for those not exposed. Conclusions Exposure to environmental tobacco smoke increases the risk of breast cancer. Public awareness of the negative consequences of passive smoking should be raised.
2009年,国际癌症研究机构(IARC)表示,“有限的证据表明,乳腺癌风险增加与吸烟之间存在因果关系”。众所周知,环境烟草烟雾通过发挥致癌和基因毒性作用而导致癌症。这项研究的目的是评估吸烟(主动和被动)与乳腺癌风险之间的关系。材料与方法病例/对照研究于2015 - 2019年在罗兹地区进行。病例组包括384名患有乳腺癌的女性;对照组包括298名健康女性。研究工具是一份匿名问卷。结果682名被调查者中,有吸烟史的占63%(65.4%/60.1%),目前吸烟者占22.1%,有被动吸烟暴露者占67%。在大多数情况下,妇女吸烟是由丈夫(86%)、父亲(55.5%)或两者(43.2%)造成的。与从未被动吸烟的非吸烟者相比,吸烟者(现在和过去)患乳腺癌的风险高253-271%。被动吸烟者的风险比未接触者高139%。结论接触环境中的烟草烟雾会增加患乳腺癌的风险。应提高公众对被动吸烟负面后果的认识。
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引用次数: 0
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Journal of Health Study and Medicine
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