Pub Date : 2019-01-01DOI: 10.1109/IBCAST.2019.8667123
Shaista Bibi, Shahid Hussain, Muhammad Imran Faisal
Cryptocurrency is one of the emerging online currency of the modern era. Big companies are investing in this technology. However, some established companies still hesitate to use it. According to them, it is a volatile trend which will fade up eventually. There is no such authority which will provide them feasibility information. So, investors can be helped by providing them feasibility information about locations for cryptocurrency investment around the world. This paper aims to provide the aforementioned information to the investors. The proposed methodology is based on Topic modeling along with public opinion mining about cryptocurrencies, blockchain network, bitcoin, litecoin, and ethereum. The crawled data for other cryptocurrencies are much insufficient, so that are excluded from the study. In the proposed methodology, the top locations where cryptocurrency is widely used are identified, then in that particular locations' users concerns along with their sentiment analyses are investigated. Top locations are identified such as Australia, Denmark, Netherlands, and the USA etc. Almost 83.7% tweets of Sweden show positive sentiment for cryptocurrency investment which ranks as the highest having friendly environment for cryptocurrency investment. Similarly, the UK shows the least positive perception of cryptocurrency and blockchain technology usage. Some of the noteworthy terms found are legitimacy, authorization rules, volatility, profit, investment, and fluctuations. Which describe the users’ concerns/ interests’ about cryptocurrency. Investors can focus on all these areas during business. These subtopics can help business experts to evolve their businesses’ and to make them more sustainable on the basis of public perception.
{"title":"Public Perception Based Recommendation System for Cryptocurrency","authors":"Shaista Bibi, Shahid Hussain, Muhammad Imran Faisal","doi":"10.1109/IBCAST.2019.8667123","DOIUrl":"https://doi.org/10.1109/IBCAST.2019.8667123","url":null,"abstract":"Cryptocurrency is one of the emerging online currency of the modern era. Big companies are investing in this technology. However, some established companies still hesitate to use it. According to them, it is a volatile trend which will fade up eventually. There is no such authority which will provide them feasibility information. So, investors can be helped by providing them feasibility information about locations for cryptocurrency investment around the world. This paper aims to provide the aforementioned information to the investors. The proposed methodology is based on Topic modeling along with public opinion mining about cryptocurrencies, blockchain network, bitcoin, litecoin, and ethereum. The crawled data for other cryptocurrencies are much insufficient, so that are excluded from the study. In the proposed methodology, the top locations where cryptocurrency is widely used are identified, then in that particular locations' users concerns along with their sentiment analyses are investigated. Top locations are identified such as Australia, Denmark, Netherlands, and the USA etc. Almost 83.7% tweets of Sweden show positive sentiment for cryptocurrency investment which ranks as the highest having friendly environment for cryptocurrency investment. Similarly, the UK shows the least positive perception of cryptocurrency and blockchain technology usage. Some of the noteworthy terms found are legitimacy, authorization rules, volatility, profit, investment, and fluctuations. Which describe the users’ concerns/ interests’ about cryptocurrency. Investors can focus on all these areas during business. These subtopics can help business experts to evolve their businesses’ and to make them more sustainable on the basis of public perception.","PeriodicalId":335329,"journal":{"name":"2019 16th International Bhurban Conference on Applied Sciences and Technology (IBCAST)","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132194550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.1109/IBCAST.2019.8667220
Talha Farooq Khan, Mohsin Muhyuddin, S. Husain, Muhammad Abdul Basit
Metal oxide nanomaterials exhibit high chemical and physical stability, non-toxic nature, and attractive biological properties, hence they are part of one of the most important classes of materials. Zinc oxide is a very commonly used semiconductor, having potential applications in optoelectronics, ultraviolet lasers and detectors, sensors, photovoltaic cells, photo-electrochemical cells and photocatalysts [1] – [5] . Most of these applications involve the ability of ZnO nanostructures to utilize light and effectively separate the photogenerated electrons and holes. Being a wide bandgap semiconductor (3.37 eV) [6] , ZnO is only able to harvest light in the ultraviolet (UV) region. In order to make sure that the visible light is also effectively utilized, the most common strategy is to functionalize the surface of ZnO with other semiconductors. For this reason, researchers have successfully functionalized the surface of ZnO nanostructures with narrow bandgap semiconductors such as CdS [7] , Cu 2 O [8] , CdSe [9] , CdTe [10] – [12] , etc. which act as sensitizer to absorb light with a greater spectrum range [13] . Similarly, ZnO has also been incorporated with wide bandgap semiconductors such as TiO 2 , SnO 2, and ZnS in order to improve utilization of ultraviolet (UV) spectrum of solar light. Fabrication of ZnO-TiO 2 architectures resulted in an increased light absorption, higher photo-induced current, and more effective charge separation [14] , [15] . Synthesis of ZnO coupled with SnO 2 produced unique luminescence properties and improved photocatalytic performance [16] – [18] .
{"title":"Synthesis and Characterization of ZnO-ZnS Nanoflowers for Enhanced Photocatalytic Performance : ZnS Decorated ZnO Nanoflowers","authors":"Talha Farooq Khan, Mohsin Muhyuddin, S. Husain, Muhammad Abdul Basit","doi":"10.1109/IBCAST.2019.8667220","DOIUrl":"https://doi.org/10.1109/IBCAST.2019.8667220","url":null,"abstract":"Metal oxide nanomaterials exhibit high chemical and physical stability, non-toxic nature, and attractive biological properties, hence they are part of one of the most important classes of materials. Zinc oxide is a very commonly used semiconductor, having potential applications in optoelectronics, ultraviolet lasers and detectors, sensors, photovoltaic cells, photo-electrochemical cells and photocatalysts [1] – [5] . Most of these applications involve the ability of ZnO nanostructures to utilize light and effectively separate the photogenerated electrons and holes. Being a wide bandgap semiconductor (3.37 eV) [6] , ZnO is only able to harvest light in the ultraviolet (UV) region. In order to make sure that the visible light is also effectively utilized, the most common strategy is to functionalize the surface of ZnO with other semiconductors. For this reason, researchers have successfully functionalized the surface of ZnO nanostructures with narrow bandgap semiconductors such as CdS [7] , Cu 2 O [8] , CdSe [9] , CdTe [10] – [12] , etc. which act as sensitizer to absorb light with a greater spectrum range [13] . Similarly, ZnO has also been incorporated with wide bandgap semiconductors such as TiO 2 , SnO 2, and ZnS in order to improve utilization of ultraviolet (UV) spectrum of solar light. Fabrication of ZnO-TiO 2 architectures resulted in an increased light absorption, higher photo-induced current, and more effective charge separation [14] , [15] . Synthesis of ZnO coupled with SnO 2 produced unique luminescence properties and improved photocatalytic performance [16] – [18] .","PeriodicalId":335329,"journal":{"name":"2019 16th International Bhurban Conference on Applied Sciences and Technology (IBCAST)","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133053669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.1109/IBCAST.2019.8667134
M. Sohail, M. Ismail, Sheikh Arslan Ali
A complete Reynolds Averaged Navier-Stokes solution of supersonic aircraft is conducted to study the nozzle plume effects on the external aerodynamics of the supersonic vehicle. Different nozzle pressure ratios are used to simulate the supersonic flow for detail study of supersonic flow behavior around vehicle in the presence of jet plume. It is found that Plume at different nozzle pressure ratio changed the flow structure around vehicle and its sonic boom signature strength. The strength of sonic boom signature is varied with the change of nozzle pressure ratios. It is observed that highly under-expanded jet plume of nozzle produces very steeper shock which reduces the dip of sonic boom N-wave signature. In this effort structure of plumes for different nozzle pressure ratios are also investigated. It is observed that higher order schemes of minimum second order are to be used to capture the free shear layers, shock train and mixing layers.
{"title":"CFD Analysis of Jet Plume Shock and Sonic Boom Signatures Interaction with Different Nozzle Pressure Ratios","authors":"M. Sohail, M. Ismail, Sheikh Arslan Ali","doi":"10.1109/IBCAST.2019.8667134","DOIUrl":"https://doi.org/10.1109/IBCAST.2019.8667134","url":null,"abstract":"A complete Reynolds Averaged Navier-Stokes solution of supersonic aircraft is conducted to study the nozzle plume effects on the external aerodynamics of the supersonic vehicle. Different nozzle pressure ratios are used to simulate the supersonic flow for detail study of supersonic flow behavior around vehicle in the presence of jet plume. It is found that Plume at different nozzle pressure ratio changed the flow structure around vehicle and its sonic boom signature strength. The strength of sonic boom signature is varied with the change of nozzle pressure ratios. It is observed that highly under-expanded jet plume of nozzle produces very steeper shock which reduces the dip of sonic boom N-wave signature. In this effort structure of plumes for different nozzle pressure ratios are also investigated. It is observed that higher order schemes of minimum second order are to be used to capture the free shear layers, shock train and mixing layers.","PeriodicalId":335329,"journal":{"name":"2019 16th International Bhurban Conference on Applied Sciences and Technology (IBCAST)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127075168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.1109/IBCAST.2019.8667199
Rida Gillani, Ali Nasir
This paper proposes a Markov decision process based model for proactive control of hybrid electric vehicle that results in optimal control policy which maximizes fuel efficiency. Novel aspect of the model is inclusion of supplied power in the state space and inclusion of difference between supplied and demanded power in the reward function of the model. This inclusion allows for supplied and demanded power of the vehicle to be different which is not catered for in previous work. Another advantage of the proposed model over existing approaches is proactive nature of control, in that, the control policy restricts the supplied power when the vehicle is running low on fuel and/or battery charge level. Such control can save precious fuel and avoid the situation of being stranded on a highway with empty fuel tank. Simulation based case study has been included for demonstration of the results from optimal policy.
{"title":"Proactive Control of Hybrid Electric Vehicles for Maximum Fuel Efficiency","authors":"Rida Gillani, Ali Nasir","doi":"10.1109/IBCAST.2019.8667199","DOIUrl":"https://doi.org/10.1109/IBCAST.2019.8667199","url":null,"abstract":"This paper proposes a Markov decision process based model for proactive control of hybrid electric vehicle that results in optimal control policy which maximizes fuel efficiency. Novel aspect of the model is inclusion of supplied power in the state space and inclusion of difference between supplied and demanded power in the reward function of the model. This inclusion allows for supplied and demanded power of the vehicle to be different which is not catered for in previous work. Another advantage of the proposed model over existing approaches is proactive nature of control, in that, the control policy restricts the supplied power when the vehicle is running low on fuel and/or battery charge level. Such control can save precious fuel and avoid the situation of being stranded on a highway with empty fuel tank. Simulation based case study has been included for demonstration of the results from optimal policy.","PeriodicalId":335329,"journal":{"name":"2019 16th International Bhurban Conference on Applied Sciences and Technology (IBCAST)","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131074404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.1109/IBCAST.2019.8667147
Qaisar Shafi, A. Basit
Distributed Denial of Service (DDoS) attacks have two defense perspectives firstly, to defend your network, resources and other information assets from this disastrous attack. Secondly, to prevent your network to be the part of botnet (botforce) bondage to launch attacks on other networks and resources mainly be controlled from a control center. This work focuses on the development of a botnet prevention system for Internet of Things (IoT) that uses the benefits of both Software Defined Networking (SDN) and Distributed Blockchain (DBC). We simulate and analyze that using blockchain and SDN, how can detect and mitigate botnets and prevent our devices to play into the hands of attackers.
{"title":"DDoS Botnet Prevention using Blockchain in Software Defined Internet of Things","authors":"Qaisar Shafi, A. Basit","doi":"10.1109/IBCAST.2019.8667147","DOIUrl":"https://doi.org/10.1109/IBCAST.2019.8667147","url":null,"abstract":"Distributed Denial of Service (DDoS) attacks have two defense perspectives firstly, to defend your network, resources and other information assets from this disastrous attack. Secondly, to prevent your network to be the part of botnet (botforce) bondage to launch attacks on other networks and resources mainly be controlled from a control center. This work focuses on the development of a botnet prevention system for Internet of Things (IoT) that uses the benefits of both Software Defined Networking (SDN) and Distributed Blockchain (DBC). We simulate and analyze that using blockchain and SDN, how can detect and mitigate botnets and prevent our devices to play into the hands of attackers.","PeriodicalId":335329,"journal":{"name":"2019 16th International Bhurban Conference on Applied Sciences and Technology (IBCAST)","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134294651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.1109/IBCAST.2019.8667167
S. Khan, U. Ahmed, Sallar Qazi, S. Nisar, M. A. Khan, K. Khan, Farrauk Rasheed, Muhammad Farhan
Image processing techniques can be utilized in analyzing amplitude and frequency of vibrating structures. It is a form of non-contact method which is suitable for cases where application of contact devices could alter the frequency of structure. This paper covers the study based on vision system that performs amplitude and frequency measurement of a cantilever beam in near real time, using image processing and computer vision toolbox in MATLAB. The vision system then detects changes in amplitude followed by feedback mechanism to ensure operation at resonance frequency. The system includes a high speed camera which is able to detect amplitude and frequency of cantilever beam vibrating at a frequency with the help of mechanical exciter. The high speed camera captures images of the beam, that are processed by a MATLAB script for evaluation of amplitude and frequency. To locate amplitude of the vibrating beam, centroid recognition technique is used which tracks the centroids of the beam in consecutive frames and plots number of pixels moved by the centroid with respect to time. Later, frequency is found out on the basis of intensity change over the time. Amplitude analysis is done at different frequencies which are automatically adjusted with the help of microcontroller to determine the resonance point. Exciter continues to vibrate at the resonant frequency until a change in amplitude is detected, implying the formation of crack. At which point the system adjusts its vibrating frequency accordingly to adjust with the new resonant frequency. This paper covers proper experimental procedure backed with the results.
{"title":"Frequency and Amplitude Measurement of A Cantilever Beam Using Image Processing : With A Feedback System","authors":"S. Khan, U. Ahmed, Sallar Qazi, S. Nisar, M. A. Khan, K. Khan, Farrauk Rasheed, Muhammad Farhan","doi":"10.1109/IBCAST.2019.8667167","DOIUrl":"https://doi.org/10.1109/IBCAST.2019.8667167","url":null,"abstract":"Image processing techniques can be utilized in analyzing amplitude and frequency of vibrating structures. It is a form of non-contact method which is suitable for cases where application of contact devices could alter the frequency of structure. This paper covers the study based on vision system that performs amplitude and frequency measurement of a cantilever beam in near real time, using image processing and computer vision toolbox in MATLAB. The vision system then detects changes in amplitude followed by feedback mechanism to ensure operation at resonance frequency. The system includes a high speed camera which is able to detect amplitude and frequency of cantilever beam vibrating at a frequency with the help of mechanical exciter. The high speed camera captures images of the beam, that are processed by a MATLAB script for evaluation of amplitude and frequency. To locate amplitude of the vibrating beam, centroid recognition technique is used which tracks the centroids of the beam in consecutive frames and plots number of pixels moved by the centroid with respect to time. Later, frequency is found out on the basis of intensity change over the time. Amplitude analysis is done at different frequencies which are automatically adjusted with the help of microcontroller to determine the resonance point. Exciter continues to vibrate at the resonant frequency until a change in amplitude is detected, implying the formation of crack. At which point the system adjusts its vibrating frequency accordingly to adjust with the new resonant frequency. This paper covers proper experimental procedure backed with the results.","PeriodicalId":335329,"journal":{"name":"2019 16th International Bhurban Conference on Applied Sciences and Technology (IBCAST)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134152259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.1109/IBCAST.2019.8667231
R. Anjum, A. Yar, I. K. Yousufzai, Q. Ahmed, A. I. Bhatti
The engine speed depends on the torque demand and load torque acting on the engine. The purpose of speed tracking is to keep the engine speed at prescribed set-points in the presence of disturbances. In this article, a speed tracking control strategy is proposed for spark ignition engines. Higher order sliding mode-based control algorithm is formulated for the speed tracking. The proposed methodology is applied to the novel first principle based engine model of the spark ignition engine instead of the mean value engine model. The fuel mass injected per combustion cycle is controlled by super-twisting algorithm based control scheme to robustly achieve the desired objective. The controller is implemented in MATLAB/Simulink and simulation results demonstrated validity of the proposed technique.
{"title":"Speed Tracking of Spark Ignition Engines using Higher Order Sliding Mode Control","authors":"R. Anjum, A. Yar, I. K. Yousufzai, Q. Ahmed, A. I. Bhatti","doi":"10.1109/IBCAST.2019.8667231","DOIUrl":"https://doi.org/10.1109/IBCAST.2019.8667231","url":null,"abstract":"The engine speed depends on the torque demand and load torque acting on the engine. The purpose of speed tracking is to keep the engine speed at prescribed set-points in the presence of disturbances. In this article, a speed tracking control strategy is proposed for spark ignition engines. Higher order sliding mode-based control algorithm is formulated for the speed tracking. The proposed methodology is applied to the novel first principle based engine model of the spark ignition engine instead of the mean value engine model. The fuel mass injected per combustion cycle is controlled by super-twisting algorithm based control scheme to robustly achieve the desired objective. The controller is implemented in MATLAB/Simulink and simulation results demonstrated validity of the proposed technique.","PeriodicalId":335329,"journal":{"name":"2019 16th International Bhurban Conference on Applied Sciences and Technology (IBCAST)","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114715052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.1109/IBCAST.2019.8667166
Z. Rehman, S. Altaf, Saleem Iqbal
Cyber Physical System (CPS) is an emerging field and further considerable research topic in multiple domains. Health monitoring is one of sub-fields in Cyber Physical System and relies heavily on wireless environment for connectivity. Due to prevailing interest in this field, security of the data is key concern when it is accessed from remote location. As it is being utilized by medical practitioner to make health related decisions risk of intrusion is always present. Any breach can cause adverse effects to patient’s health. Therefore, importance of data authenticity, freshness and encumbrance free access becomes vital in this perspective. The multiple security solutions have been found in literature. However, security solutions depend severely on authentication schemes. An adequate authentication scheme can ensure protection against cyber adversaries. The main objective of this paper is to present state-of-the-art review on security challenges, security requirements and current authentication schemes available in literature pertaining to health monitoring. These authentication schemes are analyzed on predefined parameter/features in order to testify efficacy of schemes.
{"title":"Survey of Authentication Schemes for Health Monitoring: A Subset of Cyber Physical System","authors":"Z. Rehman, S. Altaf, Saleem Iqbal","doi":"10.1109/IBCAST.2019.8667166","DOIUrl":"https://doi.org/10.1109/IBCAST.2019.8667166","url":null,"abstract":"Cyber Physical System (CPS) is an emerging field and further considerable research topic in multiple domains. Health monitoring is one of sub-fields in Cyber Physical System and relies heavily on wireless environment for connectivity. Due to prevailing interest in this field, security of the data is key concern when it is accessed from remote location. As it is being utilized by medical practitioner to make health related decisions risk of intrusion is always present. Any breach can cause adverse effects to patient’s health. Therefore, importance of data authenticity, freshness and encumbrance free access becomes vital in this perspective. The multiple security solutions have been found in literature. However, security solutions depend severely on authentication schemes. An adequate authentication scheme can ensure protection against cyber adversaries. The main objective of this paper is to present state-of-the-art review on security challenges, security requirements and current authentication schemes available in literature pertaining to health monitoring. These authentication schemes are analyzed on predefined parameter/features in order to testify efficacy of schemes.","PeriodicalId":335329,"journal":{"name":"2019 16th International Bhurban Conference on Applied Sciences and Technology (IBCAST)","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115455898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.1109/IBCAST.2019.8667146
K. Dang, Yongguang Gao, A. Qian, Jing Dong
After the first microRNA MicroRNA-let4 was found by Lee in 1993 in his study of the development of nematodes, microRNAs have been receiving increasing focus worldwide. MicroRNAs were a group of single-chain RNAs consisting of 18-25 bases, which are capable of combining with the 3’- UTR (untranslated regions) of the mRNA transcribed from the original gene, so as to control the expression of the target gene by inhibiting the translation of its mRNA(s). Accumulative evidence has manifested that microRNAs were closely correlated with the initiation and development of carcinomas. The expression of microRNAs could vary a lot across different stages in the development of cancerous cells with corresponding roles in each stage, including promoting the propagation, accelerating metastasis, and both functions combined. In this respect, we might intervene in the advances of carcinomas and even cure cancers by regulating the expressions of relevant microRNAs. The aberrant expression of microRNAs of cancerous cells give rise to potential targeted diagnosis and treatment of cancers. Moreover, further study of microRNAs might provide novel approaches for combating cancer without affecting normal cells in the molecular level. Herein, we reviewed the functions, mechanisms, and therapeutic utilities of microRNAs in the progression of colorectal cancer cells.
{"title":"Advances in the Treatment of Colorectal Cancer Using MicroRNA","authors":"K. Dang, Yongguang Gao, A. Qian, Jing Dong","doi":"10.1109/IBCAST.2019.8667146","DOIUrl":"https://doi.org/10.1109/IBCAST.2019.8667146","url":null,"abstract":"After the first microRNA MicroRNA-let4 was found by Lee in 1993 in his study of the development of nematodes, microRNAs have been receiving increasing focus worldwide. MicroRNAs were a group of single-chain RNAs consisting of 18-25 bases, which are capable of combining with the 3’- UTR (untranslated regions) of the mRNA transcribed from the original gene, so as to control the expression of the target gene by inhibiting the translation of its mRNA(s). Accumulative evidence has manifested that microRNAs were closely correlated with the initiation and development of carcinomas. The expression of microRNAs could vary a lot across different stages in the development of cancerous cells with corresponding roles in each stage, including promoting the propagation, accelerating metastasis, and both functions combined. In this respect, we might intervene in the advances of carcinomas and even cure cancers by regulating the expressions of relevant microRNAs. The aberrant expression of microRNAs of cancerous cells give rise to potential targeted diagnosis and treatment of cancers. Moreover, further study of microRNAs might provide novel approaches for combating cancer without affecting normal cells in the molecular level. Herein, we reviewed the functions, mechanisms, and therapeutic utilities of microRNAs in the progression of colorectal cancer cells.","PeriodicalId":335329,"journal":{"name":"2019 16th International Bhurban Conference on Applied Sciences and Technology (IBCAST)","volume":"381 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124741345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.1109/IBCAST.2019.8667265
Umar Dilshad, Chen Chen, Xi Chen, J. Miao
This paper presents the design architecture of millimeter-wave receiver in which the un-desired image frequency band can be rejected at the IF stage using broadband quadrature hybrid. This scheme requires quadrature de-modulation/ down-conversion of the received signal at the front end; followed by quadrature hybrid at IF stage. The image rejection ratio (IRR) depends on the amplitude imbalance and phase imbalance of this quadrature hybrid. The design of C-Band broadband quadrature hybrid; based on 3-stage micro-strip cascaded branch-line topology; has been proposed for this receiver. The proposed broadband quadrature hybrid exhibits 66 % fractional bandwidth corresponding to measured amplitude balance of better than ±0.85 dB, phase imbalance better than 3 degrees, return loss and isolation better than 15 dB, in the frequency range (4-8 GHz). This quadrature hybrid shows tight 3-dB quadrature coupling response in much wider band; as compared to earlier published design schemes, to the best of our knowledge. This quadrature hybrid integrated in the proposed millimeter wave receiver (32-36 GHz) achieved IRR better than 20 dB in the whole frequency band.
{"title":"Broadband Quadrature Hybrid for Image Rejection in Millimeter-wave Receivers","authors":"Umar Dilshad, Chen Chen, Xi Chen, J. Miao","doi":"10.1109/IBCAST.2019.8667265","DOIUrl":"https://doi.org/10.1109/IBCAST.2019.8667265","url":null,"abstract":"This paper presents the design architecture of millimeter-wave receiver in which the un-desired image frequency band can be rejected at the IF stage using broadband quadrature hybrid. This scheme requires quadrature de-modulation/ down-conversion of the received signal at the front end; followed by quadrature hybrid at IF stage. The image rejection ratio (IRR) depends on the amplitude imbalance and phase imbalance of this quadrature hybrid. The design of C-Band broadband quadrature hybrid; based on 3-stage micro-strip cascaded branch-line topology; has been proposed for this receiver. The proposed broadband quadrature hybrid exhibits 66 % fractional bandwidth corresponding to measured amplitude balance of better than ±0.85 dB, phase imbalance better than 3 degrees, return loss and isolation better than 15 dB, in the frequency range (4-8 GHz). This quadrature hybrid shows tight 3-dB quadrature coupling response in much wider band; as compared to earlier published design schemes, to the best of our knowledge. This quadrature hybrid integrated in the proposed millimeter wave receiver (32-36 GHz) achieved IRR better than 20 dB in the whole frequency band.","PeriodicalId":335329,"journal":{"name":"2019 16th International Bhurban Conference on Applied Sciences and Technology (IBCAST)","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127809198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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