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A 5 year retrospective analysis of pharmacovigilance study, completeness and quality of suspected adverse drug reaction forms at adverse drug reaction monitoring center Port Blair. 布莱尔港药物不良反应监测中心5年药物警戒研究、可疑药物不良反应表格的完整性和质量回顾性分析
Pub Date : 2021-12-15 DOI: 10.33762/mjbu.2021.130470.1077
P. Hotha, C. Naidu, Nimisha Elezebeth Zachariah
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引用次数: 0
Antenatal care field survey in the catchment area of Bab Al-Moatham Primary Health Care center, Baghdad 在巴格达Bab Al-Moatham初级卫生保健中心集水区进行产前保健实地调查
Pub Date : 2021-12-15 DOI: 10.33762/mjbu.2022.131231.1086
Hassan Alkazzaz, Khelowd Salih, R. Farhan, sahar alshatari
ANC is described as care provided to pregnant women and adolescent girls by experienced personnel with substantial healthcare training in order to ensure the greatest possible health circumstances for both the mother and the fetus throughout gestation. The objective of this study is to find the percentage of antenatal care booking, care regularity and antenatal care irregularity. This study is a cross-sectional field survey with an analytic element conducted from 1 January -1 July 2018. We chose 10% of all the catchment area (shown in block numbers) as a two-stage cluster sampling method. Fifteen clusters (one cluster for every 180 families in the block) were chosen, each with 15 households, for a total of 225 households. There were two to three married women of reproductive age (15-49 years old) in some houses, bringing the total female participation to 255.This study was done in Bab Al-Moatham Primary Health care center. it revealed that most houses 195(76.47%) have one adult woman of reproductive age per house, 106(41.6%) of participant's age between 30-39 years, 77(30.2%) married between 20122007, and 87(34.1%) completed primary school. In concern to women reproductive history, the highest percentage have two pregnancies, two babies, without abortion or stillbirth. Out of 255 studied women, During the previous three years, 236 women were pregnant, 191(80.93%) of them had ANC booking, 148(58.1%) have regular ANC visit, while 43(16.9%) have irregular ANC visiting, and 188(98.43%) of them had ANC card. Abortion represents a major problem for irregularity in consuming ANC services. Improving health services and health promotion are essential steps in reducing abortion which might lead to increase ANC booking.
产前护理被描述为由受过大量保健培训的经验丰富的人员向孕妇和少女提供的护理,以确保在整个妊娠期间母亲和胎儿都有尽可能好的健康环境。本研究的目的是找出产前护理预约,护理规律和产前护理不规律的百分比。本研究是2018年1月1日至7月1日进行的一项带有分析元素的横断面实地调查。我们选择了所有流域面积的10%(以块号显示)作为两阶段聚类抽样方法。选择了15个集群(每180户家庭一个集群),每个集群有15户,总共225户。有些家庭中有2至3名育龄已婚妇女(15-49岁),使参与的妇女总数达到255人。这项研究是在Bab Al-Moatham初级保健中心进行的。调查显示,大多数家庭195个(76.47%)每个家庭有一名育龄成年女性,106个(41.6%)参与者年龄在30-39岁之间,77个(30.2%)参与者在2012 - 2007年之间结婚,87个(34.1%)参与者完成小学教育。关于妇女的生育史,最高的百分比是两次怀孕,两个婴儿,没有堕胎或死产。在255名被研究的妇女中,在过去三年中,236名妇女怀孕,其中191名(80.93%)预订了ANC, 148名(58.1%)定期进行ANC检查,43名(16.9%)不定期进行ANC检查,188名(98.43%)有ANC卡。堕胎是非国大服务消费不正常的一个主要问题。改善保健服务和促进健康是减少堕胎的必要步骤,堕胎可能导致非分娩预约人数增加。
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引用次数: 0
Clinical presentation and electrocardiographic features of Brugada syndrome in Iraq 伊拉克Brugada综合征的临床表现和心电图特征
Pub Date : 2021-12-15 DOI: 10.33762/mjbu.2021.130674.1080
A. AL-Hamdi
Background: Brugada syndrome is a clinical entity composed of twelve leads electrocardiographic changes of coved or saddle shaped STsegment elevation in V1 and V2 with serious ventricular arrhythmias which may cause sudden cardiac death. Objectives: The objectives of this study is to highlight the clinical presentation and the types of ECG changes of Brugada syndrome cases seen in Iraq and to orient physicians about this fatal condition. Patients and Methods: Patients presented with symptoms of palpitation, dizzy attacks or syncope and diagnosed as Brugada syndrome were included in this case series study. The diagnosis of Brugada syndrome based mainly on the typical coved or saddle shaped or variant STSegment elevation in electrocardiographic leads V1, V2. Results: Eighteen patients were included in this case series study. All are males. Age ranged from 15-45 Y. The presenting symptoms were palpitation in 12 patients, syncope in 8, dizzy spells and pre syncope in 14 and chest pain seen in 2. The arrhythmic events were clinically documented in 10. Monomorphic VT seen in 4, VF in 2, atrial fibrillation in 2 and atrial flutter in 2. Induced VF by EP study seen in 2. Type I Brugada ECG pattern was seen in 6 patients, type II in 4 and three of type III. Five showed a variant type of the syndrome. Family history of sudden cardiac death was seen in 8 patients while in 10 it was negative. ICD was implanted in 6 patients. In 12 patients (67%) the diagnosis of Brugada syndrome was missed during the provisional medical contacts. Conclusion: Brugada syndrome is not uncommon in Iraq but needs a high diagnostic suspicion through appreciating the symptomologies and electrocardiographic features of this fatal syndrome to plan management to prevent sudden cardiac death.
背景:Brugada综合征是一种临床症状,由12导联心电图改变为V1、V2段呈锥形或鞍状抬高,伴严重室性心律失常,可引起心源性猝死。目的:本研究的目的是强调在伊拉克看到的Brugada综合征病例的临床表现和心电图变化类型,并指导医生了解这种致命的疾病。患者和方法:以心悸、头晕发作或晕厥为症状并诊断为Brugada综合征的患者纳入本病例系列研究。Brugada综合征的诊断主要基于心电图导联V1、V2中典型的冠状、鞍状或变异型st段抬高。结果:18例患者纳入本病例系列研究。都是雄性。年龄15-45岁,主要症状为心悸12例,晕厥8例,晕眩和晕厥前期14例,胸痛2例。10年的心律失常事件被临床记录。单纯性房颤4例,室颤2例,房颤2例,心房扑动2例。2. EP诱发VF。Brugadaⅰ型心电图6例,ⅱ型4例,ⅲ型3例。其中5人表现出该综合征的变体类型。心源性猝死家族史8例,阴性10例。6例患者植入ICD。在12例(67%)患者中,在临时医疗接触期间错过了Brugada综合征的诊断。结论:Brugada综合征在伊拉克并不少见,但应通过对该致命综合征的症状和心电图特征的认识,提高诊断的可信度,制定预防心源性猝死的治疗方案。
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引用次数: 0
Ready to-Use Supplementary Food in the Outpatient Management of Children with Acute Malnutrition in Basrah 在巴士拉急性营养不良儿童门诊管理中的即食补充食品
Pub Date : 2021-12-15 DOI: 10.33762/mjbu.2021.130966.1085
Nedhal Kudhayer, S. Habib
Background Ready-to-use supplementary foods are high-energy, lipid-based provide energy, protein, fat, vitamins and minerals to treat acute malnutrition in children aged 6 -59 months. Aim To evaluate the effect of ready-to-use supplement foods on the outpatient management of children with acute malnutrition. Methods A prospective appropriate study was carried out on children with acute malnutrition who were referred to the nutritional rehabilitation center at Basra Teaching Hospital; were received ready-touse supplementary foods at a quantity sufficient to meet their nutrient requirements for full catchup growth and followed at two subsequent visits Results Moderate wasting and underweight recorded in (66.7 %) and severe wasting in (33.33%) of the patients. Mean weight gain at the first and second follow-up visit was (5.78 ±2.43) and (6.52 ±2.75) g/kg/day respectively. There was a significant improvement in the weight for height Z score at the first and second follow-up visits after the administration of ready-to-use supplementary foods (P value < 0.05). Approximately 32% of the children aged 12-18-month experienced moderate weight gain. Bottle feeding with complementary feeding was reported in 24.19% of the children with moderate weight gain, and 9.52% and 34.68% of the children of illiterate parents and unemployed fathers respectively, showed moderate weight gain. Children belong to families with low income group accounted for 37.09% of those with moderate weight gain. Family income was the only variable that depend on the weight gain results (P value < 0.05). Conclusion: Readyto-use supplementary food is significantly effective for outpatient management of acute malnutrition.
即食辅食是高能量、以脂质为基础的食品,可提供能量、蛋白质、脂肪、维生素和矿物质,用于治疗6 -59个月儿童的急性营养不良。目的评价即食辅食在急性营养不良患儿门诊管理中的作用。方法对转诊至巴士拉教学医院营养康复中心的急性营养不良患儿进行前瞻性研究;在随后的两次随访中,给予足够数量的补食,以满足其完全追赶生长所需的营养需求。结果中度消瘦和体重不足的患者占66.7%,重度消瘦的患者占33.33%。第一次和第二次随访时平均体重增加分别为(5.78±2.43)g/kg/d和(6.52±2.75)g/kg/d。在给予即食辅食后的第一次和第二次随访中,身高Z评分的体重有显著改善(P值< 0.05)。大约32%的12-18个月大的儿童体重有中度增加。轻度体重增加的儿童以奶瓶喂养加辅食的比例为24.19%,父母不识字的儿童体重增加比例为9.52%,父亲失业的儿童体重增加比例为34.68%。中等体重增加人群中,低收入家庭儿童占37.09%。家庭收入是影响增重结果的唯一变量(P值< 0.05)。结论:即食辅食对门诊急性营养不良患者的治疗效果显著。
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引用次数: 0
The effect of tourniquet on early postoperative quadriceps muscle wasting in ACL arthroscopic surgery 止血带对ACL关节镜手术术后早期股四头肌萎缩的影响
Pub Date : 2021-12-15 DOI: 10.33762/mjbu.2021.131456.1088
M. Mahdi, Hussein Al Yusir
Background: The main goals of anterior cruciate ligament (ACL) reconstruction and rehabilitation are to reestablish knee function. Quadriceps weakness is one of the most important complications associated with ACL injury and represents a major rehabilitation challenge. This study is designed to test the early effect of tourniquet on muscle wasting and to differentiate weather it is because muscle disuse or injury. Methods: Twenty six male patients who submit to arthroscopic ACL reconstruction were randomly assigned to the use of an inflated (group T, n _ 13) or deflated (group NT, n _ 13) tourniquet. Patients with preoperative quadriceps wasting or abnormal electro conductive studies were excluded. The primary measures were thigh girth preoperatively and after two weeks, serum creatinine phosphokinase (CPK) preoperatively and one day postoperatively and electro conductive studies preoperatively and 1 month postoperatively. Results: Patients' mean age was comparable in both groups. There was a significant difference between T and NT groups in term of thigh girth, CPK and electro conductive studies. Mean thigh girth in T group was 2.6 ± 0.5 while in NT group 1.4 ± 0.5. Mean CPK in T group was 813 ± 149 while in NT group 520 ± 203. Mean femoral latency was 1.85 ± 0.4 in T group and 1 ± 0 in NT group; mean femoral conduction velocity was 1.77 ± 0.4 in T group and 1 ± 0 in NT group; mean muscle denervation was 1.92 ± 0.3 in T group and 1.54 ± 0.5 in NT group; mean motor unit number estimation was 1.9 ± 0.3 in T group and 1.5 ± 0.5 in NT group. Conclusion: This comparative study show that tourniquet play a significant role in direct muscle injury proved by measurement of postoperative CPK and thigh girth in T group comparing it with NT group.
背景:前交叉韧带(ACL)重建与康复的主要目的是重建膝关节功能。股四头肌无力是与前交叉韧带损伤相关的最重要的并发症之一,也是一个主要的康复挑战。本研究旨在测试止血带对肌肉萎缩的早期影响,并区分它是由于肌肉的废用还是损伤。方法:26例接受关节镜下ACL重建的男性患者,随机分为充气止血带(T组,n _ 13)和充气止血带(NT组,n _ 13)两组。术前有股四头肌萎缩或导电异常的患者被排除在外。主要测量指标为术前及术后2周大腿围、术前及术后1天血清肌酐磷酸激酶(CPK)、术前及术后1个月的电导率。结果:两组患者的平均年龄相当。T组和NT组在大腿围、CPK和电导率方面有显著差异。T组平均大腿围为2.6±0.5,NT组平均大腿围为1.4±0.5。T组平均CPK为813±149,NT组平均CPK为520±203。T组平均股潜伏期1.85±0.4,NT组平均股潜伏期1±0;T组股骨平均传导速度为1.77±0.4,NT组为1±0;T组肌肉去神经支配平均为1.92±0.3,NT组为1.54±0.5;T组和NT组的平均运动单位数分别为1.9±0.3和1.5±0.5。结论:通过对T组与NT组术后CPK和大腿围的测量,对比研究表明止血带在直接肌肉损伤中发挥了重要作用。
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引用次数: 0
The Effect of Fasting and Smoking on the severity and mortality of COVID-19 patients in Basrah, Iraq 禁食和吸烟对伊拉克巴士拉市COVID-19患者严重程度和死亡率的影响
Pub Date : 2021-12-15 DOI: 10.33762/mjbu.2021.127786.1028
Jawd Albazoony
Background:Fasting has been shown to have an impact body systems in different manners. The influence of fasting on immune system regulation remains controversial. Immunomodulatory effect of nicotine was suggested recently. Low prevalence of smoking was observed among patients with COVID-19.Aim: To study fasting as an immune modulator in relation to the severity and mortality of COVID-19 patients, and to determine the effect of smoking on such patients. Methods:This is a comparative study included all PCR-confirmed COVID-19 patients during April, May and June 2020 in Basrah. The severity of and mortality due to COVID-19 infection were studied in fasting patients in Ramadan as compared with the non-fasting months before and one month later. Current smoking in relation to the severity of infection was also studied. Results :Significantly less severe cases and lower mortality were detected in patients with COVID-19 who were fasting as compared with non-fasting patients before and after the fasting month. Current smoking is significantly less frequently detected among severe as compared with mild to moderate cases. Conclusion Fasting could be useful to improve immune response against infection and to reduce severity and mortality in patients with infections. Smoking benefit in preventing and ameliorating of respiratory tract infection needs to be further investigated. .
背景:禁食已被证明对身体系统有不同方式的影响。禁食对免疫系统调节的影响仍有争议。尼古丁的免疫调节作用是近年来提出的。COVID-19患者的吸烟率较低。目的:研究禁食作为免疫调节剂与COVID-19患者严重程度和死亡率的关系,并确定吸烟对这类患者的影响。方法:这是一项比较研究,包括2020年4月、5月和6月在巴士拉所有pcr确诊的COVID-19患者。研究了斋月禁食患者与斋月前和一个月后非禁食患者的COVID-19感染严重程度和死亡率。目前吸烟与感染严重程度的关系也进行了研究。结果:与禁食月前后的非禁食患者相比,禁食的COVID-19患者的重症病例和死亡率明显减少。与轻度至中度病例相比,在重度病例中发现当前吸烟的频率明显较低。结论禁食可提高感染患者的免疫应答,降低感染的严重程度和死亡率。吸烟对预防和改善呼吸道感染的益处有待进一步研究。
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引用次数: 0
Association between Taq1 rs: 731236 SNP of VDR gene and risk factor among Sudanese patients with breast cancer 苏丹乳腺癌患者VDR基因Taq1 rs: 731236 SNP与危险因素的相关性研究
Pub Date : 2021-12-15 DOI: 10.33762/mjbu.2021.130830.1082
Amira S. Khalafalla, Abuagla M. Dafalla, Y. Mohammed, A. Abakar, M. Adil, G. Modawe
Introduction: Breast cancer is the most frequent cancer in women globally as well asSudan, it has risen to become the second commonest cause of death in women.Vitamin D receptor (VDR) is a ligand-dependent transcription factor. Vitamin D-ligandedVDR, has antiproliferative properties in a variety of tumor types by inducing cell cycle arrest, senescence, differentiation, and death. The role of VDR TaqI polymorphism is currently unknown. However, studies suggest that these polymorphisms may affect messenger RNA (mRNA) stability. Methods:This case control 198 participants, (97) breast cancer patients and another 101control group.Data wascollectedby a questionnaire. 2 ml of venous blood was collected and stored at -20 till DNA extraction. Phenol chloroform method was used for DNA extraction. VDR TaqI was examined and genotyped using CTPP-PCR after designing of suitable primers and PCR condition. Then data was analyzed statistically using the SPSS program (version 21) and the SNPStats online tool. Results:the three genotypes reported in this study for TaqI SNP (CC, TC, and TT) were evenly distributed throughout cases and controls, so according to this findings there is no statistically significant association of this SNP with breast cancer risk (p. value 0.650) (OR(95%CI) 1.39 (0.64-3.00), 1.00 (0.54-1.87), 1.00). Conclusions:This study found no association of TaqI polymorphism and breast cancer riskfactors
简介:乳腺癌是全球以及苏丹妇女中最常见的癌症,它已上升为妇女死亡的第二大常见原因。维生素D受体(VDR)是一种依赖配体的转录因子。维生素d配体dvdr通过诱导细胞周期阻滞、衰老、分化和死亡,在多种肿瘤类型中具有抗增殖特性。VDR TaqI多态性的作用目前尚不清楚。然而,研究表明这些多态性可能会影响信使RNA (mRNA)的稳定性。方法:本病例对照198例,其中97例为乳腺癌患者,另设101例为对照组。通过问卷调查收集数据。取静脉血2ml, -20℃保存至提取DNA。采用苯酚-氯仿法提取DNA。设计合适的引物和PCR条件后,采用CTPP-PCR对VDR TaqI进行检测和分型。然后使用SPSS软件(版本21)和SNPStats在线工具对数据进行统计分析。结果:本研究报道的TaqI SNP的三种基因型(CC、TC、TT)在病例和对照组中分布均匀,因此根据本研究结果,该SNP与乳腺癌风险的相关性无统计学意义(p值0.650)(OR(95%CI) 1.39(0.64-3.00)、1.00(0.54-1.87)、1.00)。结论:本研究未发现TaqI多态性与乳腺癌危险因素相关
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引用次数: 0
Practical approach to train and assess professional behaviour of medical students 培养和评估医学生专业行为的实用方法
Pub Date : 2021-12-15 DOI: 10.33762/mjbu.2021.169992
G. Alsheikh
The gradual decline of doctor-patient communication skills and professional attitudes and behaviour have steadily been observed in all countries across the globe. This deterioration has resulted in repeated and renewed demands to make medical schools more aligned to the necessity to train professional behaviours in undergraduate medical study. Medical educators have been criticised for not effectively training and rigorously assessing these skills. Training of behaviour has been abstracted in teaching of ethics and communication skills which in most of the cases is based on theoretical “preaching” lectures and use of book/guide and in some cases, training using supervised role-playing sessions at the best of options. Although good communication skills are essential for an optimal doctor-patient relationship and certainly contribute to improved health outcomes, still other aspects of behaviour are not covered. Furthermore, while the need for training on professional behaviour is specified as a requirement in the adopted graduate outcomes, formal training in these skills has been fragmentary and not clearly addressed in curriculum documents of the medical colleges in Iraq. A practical approach is here proposed to support medical colleges to bridge this gap. The methods of design, construction and use of standardised checklists for training medical students and assessing their acquisition of behavioural (affective) skills is described
在全球所有国家,医患沟通技巧和专业态度和行为都在逐渐下降。这种恶化导致人们一再提出要求,要求医学院更加符合在本科医学学习中培养专业行为的必要性。医学教育者因没有有效地培训和严格评估这些技能而受到批评。行为训练被抽象为道德和沟通技巧的教学,在大多数情况下,这是基于理论上的“说教”讲座和使用书籍/指南,在某些情况下,在最好的选择下,使用有监督的角色扮演课程进行训练。虽然良好的沟通技巧对于最佳的医患关系至关重要,并且肯定有助于改善健康结果,但行为的其他方面仍未包括在内。此外,虽然在通过的毕业生成果中明确规定了对专业行为进行培训的必要性,但这些技能的正式培训是零碎的,在伊拉克医学院的课程文件中没有明确提到。这里提出了一种实用的方法来支持医学院弥合这一差距。描述了为培训医学生和评估他们获得行为(情感)技能而设计、构建和使用标准化核对表的方法
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引用次数: 1
low birth weight risk factors in Basra city 低出生体重的风险因素
Pub Date : 2021-12-15 DOI: 10.33762/mjbu.2021.129962.1070
Zainab Almussa
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引用次数: 0
Serum potassium and calcium level in patients with post-myocardial infarction ventricular fibrillation 心肌梗死后心室颤动患者血清钾、钙水平的变化
Pub Date : 2021-06-15 DOI: 10.33762/mjbu.2021.129372.1063
Z. Mahmood
Background: Arrhythmias are common in the first hours after myocardial infarction. Electrolytes imbalance often contribute to the development of cardiac arrhythmias. Aims of the study to show the correlation between serum potassium and calcium and development of post myocardial infarction ventricular fibrillation and to assess the effect of different age groups and gender in the development of this arrhythmia. Methods: Ninety-three patients, 66(70.96%) males and 27 (29%) females were studied. The mean age was 57.13±11.86 years. Patients included were those who were admitted to the cardiac care units with acute myocardial infarction in 4 hospitals in Basra (southern of Iraq), blood samples for Potassium and Calcium were taken upon admission. Results: Forty (43%) patients had developed primary ventricular fibrillation. The incidence of primary ventricular fibrillation was greater among patients with serum Potassium ≤3.5mmol/L and >4.5mmol/L (p value=0.002). Age was not associated with increased frequency of primary ventricular fibrillation in patients with abnormal serum Potassium, but the incidence of primary ventricular fibrillation as caused by abnormal serum Potassium level was higher among females. No increase in primary ventricular fibrillation was found in patients with abnormal serum Calcium. Conclusion: The incidence of post myocardial ischemic primary ventricular fibrillation was very common in patients with serum Potassium ≤3.5mmo/L and >4.5mmol/L.
背景:心律失常常见于心肌梗死后的头几个小时。电解质失衡常导致心律失常的发生。目的探讨血清钾、钙与心肌梗死后心室颤动发生的相关性,并探讨不同年龄组和性别对心肌梗死后心室颤动发生的影响。方法:对93例患者进行分析,其中男性66例(70.96%),女性27例(29%)。平均年龄57.13±11.86岁。纳入的患者是在巴士拉(伊拉克南部)的4家医院因急性心肌梗死入住心脏护理部门的患者,在入院时采集了钾和钙的血液样本。结果:40例(43%)患者发生原发性心室颤动。血清钾≤3.5mmol/L和>4.5mmol/L的患者原发性心室颤动发生率更高(p值=0.002)。在血钾异常患者中,年龄与原发性心室颤动的发生率增加无关,但血钾异常引起的原发性心室颤动的发生率在女性中较高。血清钙异常患者原发性心室颤动发生率未见增加。结论:血钾≤3.5 mmol/L、>4.5mmol/L的患者心肌缺血后原发性室颤发生率较高。
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引用次数: 0
期刊
The Medical Journal of Basrah University
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