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Knowledge and Attitude towards Do-Not-Resuscitate Order among Nurses of a Tertiary Level Hospital 某三级医院护士对“不抢救令”的认知与态度
Pub Date : 2021-09-06 DOI: 10.3126/mjsbh.v20i2.31670
Asmita Shrestha, S. Shrestha
Introduction: Knowledge regarding and attitude towards end-of-life care can shape the behaviour and actions of a health professional in provision of supportive care for the comfort of the patients as well as their family members. Very little is known about nurses’ knowledge and attitude regarding do-not-resuscitate (DNR) order. Therefore, the purpose of this study was to identify the knowledge of and attitude towards DNR order and relationship between knowledge and attitude towards DNR order among the nurses of a tertiary level hospital.  Methods: Descriptive correlation design was used.  Convenient sampling method was used to select 70 nurses from a tertiary level hospital. Data were collected using pretested self administered structured questionnaire. Data were analysed using SPSS version 20 and analysed using descriptive and inferential statistics. Result: Among 70 respondents, almost all (95.7%) of the respondents had good level of knowledge, 2.9% had fair and 1.4% had poor level of knowledge. Most (80.0%) of the respondents had positive attitude towards DNR order and 20.0% had negative attitude. There was a positive relationship between knowledge of and attitude towards DNR order (r = 0.068) but the relationship was statistically insignificant. Conclusions: Based on the findings, the study concludes that nurses of tertiary level hospital have good knowledge and positive attitude towards DNR order. Likewise, knowledge regarding DNR order is related with the attitude towards DNR order and thus knowledge can be enhanced to improve the attitude towards DNR by regular in-service education.
导言:关于临终关怀的知识和态度可以塑造卫生专业人员在提供支持性护理方面的行为和行动,以使患者及其家属感到舒适。护士对不抢救(DNR)命令的知识和态度了解甚少。因此,本研究的目的是确定三级医院护士对急诊顺序的知识和态度,以及知识和态度之间的关系。方法:采用描述性相关设计。采用方便抽样法,选取某三级医院护士70名。数据收集采用预测试的自我管理结构化问卷。数据分析采用SPSS version 20,分析采用描述性统计和推理统计。结果:70名被调查者中,几乎所有(95.7%)的人知识水平良好,2.9%的人知识水平一般,1.4%的人知识水平较差。大多数受访者(80.0%)对DNR订单持肯定态度,20.0%持否定态度。对DNR顺序的认知与态度呈正相关(r = 0.068),但无统计学意义。结论:根据调查结果,三级医院护士对急诊顺序有较好的认识和积极的态度。同样,关于DNR顺序的知识与对DNR顺序的态度有关,因此可以通过定期在职教育来增强知识以改善对DNR的态度。
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引用次数: 0
Knowledge, Acceptability, Perception and Stigmas on Safe Abortion among the women of reproductive age group (15-49 years) in Bhaktapur District. 巴克塔普尔地区育龄妇女(15-49岁)安全堕胎的知识、可接受性、认知和耻辱。
Pub Date : 2021-09-06 DOI: 10.3126/mjsbh.v20i2.37426
Ankisha Shrestha, Ram Chandra Sinha, A. Ahmad
Introduction: The termination of pregnancy by the removal of a foetus or an embryo before surviving outside the uterus or before attaining its viability is called abortion. This study was conducted to study the knowledge, acceptability, perception and stigma of safe abortion among women of reproductive age group.  Methods: A cross-sectional analytical study was carried out in Bhaktapur District, Nepal from July 2019 to December 2019. Women of reproductive age group were included in the study. The semi-structured questionnaires were used as a data collection tool and Likert scales were used for perception and stigma which were self-designed. For Likert scale on perception and stigma, Cronbach’s α was calculated from the pre-tested samples which was found to be acceptable i.e., 0.649 and 0.856. Interview was taken as data collection technique. Data-entry was done in Epi-Data and analysed through SPSS 16.0. Chi square test was used to measure the association between dependent and independent variables. Result: The association between “Knowledge and Perception” was found to be significant with p-value of 0.04, the association between “Knowledge and Stigma” was also noted to be significant with p-value of 0.00 and “Knowledge and Acceptability” was also found to be significant with p-value of 0.00 through the assessment of knowledge, acceptability, perception and stigma. Conclusions: The study emphasises on educating and making aware every woman on safe abortion, its legalisation and its amended law to avoid the stigma and unsafe abortion practices.
引言:在胎儿或胚胎在子宫外存活或达到其生存能力之前,通过移除胎儿或胚胎来终止妊娠被称为流产。本研究旨在探讨育龄妇女对安全堕胎的认知、可接受性、认知及污名。方法:于2019年7月至2019年12月在尼泊尔巴克塔普尔地区进行横断面分析研究。研究对象为育龄妇女。采用半结构化问卷作为数据收集工具,采用李克特量表自行设计感知和污名。知觉和耻感的Likert量表采用预测样本计算Cronbach’s α,分别为0.649和0.856,可接受。采用访谈作为数据收集方法。数据在Epi-Data中录入,并通过SPSS 16.0进行分析。因变量与自变量之间的相关性采用卡方检验。结果:通过对知识、可接受性、知觉和病耻感的评估,发现“知识与知觉”的相关性显著,p值为0.04;通过对知识、可接受性、知觉和病耻感的评估,发现“知识与病耻感”的相关性显著,p值为0.00;通过对“知识与病耻感”的评估,发现“知识与病耻感”的相关性显著,p值为0.00。结论:该研究强调教育和提高每个妇女对安全堕胎、其合法化及其修订法律的认识,以避免耻辱和不安全堕胎做法。
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引用次数: 0
Awareness and Practice of Junk Foods among Adolescents in Secondary Level Students 中学生青少年对垃圾食品的认知与行为
Pub Date : 2021-09-06 DOI: 10.3126/mjsbh.v20i2.30309
R. Paudel, Sarita Shrestha
Introduction: Junk food consumption among adolescents has become a serious issue that may lead to harmful effects on health. Dietary patterns of people are shifting from homemade foods to junk foods. Therefore, this study was undertaken to assess the awareness and practice of junk foods among adolescents. Methods: A descriptive cross-sectional study was conducted among adolescents of secondary level students. A simple random sampling technique was used to select the sample and the sample size was 237. Data collection was done from April 15, 2019 to May 14, 2019. A set of semi-structured self-administered questionnaire was used for data collection. Descriptive and inferential statistics were used to analyse and interpret the findings. Results: The findings showed that more than three-fifth (67.9%) of adolescents had a moderate level of awareness about junk foods. Half (49.4%) of them consumed junk foods highly. All (100%) adolescents have consumed junk foods regularly whereas two-fifth (42.2%) replaced meals once a week with junk foods. Four-fifth (82.3%) of adolescents did not bring tiffin from home. There was no significant association between the awareness and practice of junk foods (p < 0.05). Conclusions: This study concludes that most of the adolescents possessed a moderate level of awareness of junk foods. Majority of them did not bring tiffin from their home. Around half of them consumed junk foods in their daily life. Majority of them were aware of junk foods, although they still consumed junk foods.
青少年消费垃圾食品已经成为一个严重的问题,可能会对健康造成有害影响。人们的饮食模式正在从自制食品转向垃圾食品。因此,本研究旨在评估青少年对垃圾食品的认知和行为。方法:采用描述性横断面调查方法,对中学生进行调查。采用简单随机抽样方法选取样本,样本量为237例。数据收集时间为2019年4月15日至2019年5月14日。数据收集采用一套半结构化的自填问卷。描述性和推断性统计用于分析和解释研究结果。结果:调查结果显示,超过五分之三(67.9%)的青少年对垃圾食品有中等程度的认识。其中一半(49.4%)的人高度食用垃圾食品。所有(100%)青少年都经常食用垃圾食品,而五分之二(42.2%)的青少年用垃圾食品代替一周一次的正餐。五分之四(82.3%)的青少年没有从家里带午餐。对垃圾食品的认知与行为之间无显著相关性(p < 0.05)。结论:本研究得出的结论是,大多数青少年对垃圾食品有中等程度的认识。他们中的大多数人没有从家里带午餐。大约一半的人在日常生活中食用垃圾食品。他们中的大多数人都知道垃圾食品,尽管他们仍然吃垃圾食品。
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引用次数: 2
A spectrum of HRCT chest findings in RT-PCR positive asymptomatic COVID-19 patients at a COVID designated hospital in Nepal 尼泊尔某COVID指定医院RT-PCR阳性无症状COVID-19患者HRCT胸部检查谱
Pub Date : 2021-06-27 DOI: 10.1101/2021.06.25.21259523
Binamra Basnet, Sujata Pant, Sujit Pant, Kalpana Rai, N. Tulachan, Bibek Karki, R. Shahi, S. Basnet, B. Thapa
Introduction: COVID-19 pandemic is grappling the world with the surge of infection time and again. Clinicians are trying to justify the ethics of public health care. Asymptomatic COVID-19 cases are going undocumented and most of them practice self-isolation. Studies have revealed significant radiological changes among RT-PCR positive asymptomatic COVID-19 cases. Objective: The aim of this cross-sectional study is to characterized chest CT findings of asymptomatic RT-PCR-positive patients in one of the COVID designated hospitals in Nepal. Results: Out of 43, 26 (60.5%) participants had positive Chest CT scan findings consistent with COVID pneumonia. 65% had bilateral and 77% had multifocal lesions. The ground-glass opacities (92%), mixed (ground-glass opacities and consolidation) pattern (30.7%), and consolidation only (34.6%) were common chest CT findings. The median CT score was 3.5 (Interquartile range; 2-6). Conclusion: The majority of the RT-PCR positive asymptomatic patient present with CT scan changes of lungs which are important to determine clinical status, prognosis, and long-term sequel in those cohorts.
导言:2019冠状病毒病(COVID-19)大流行使世界面临感染人数一次又一次激增的问题。临床医生正试图证明公共卫生保健的道德规范。无症状的新冠肺炎患者没有记录在案,大多数人实行自我隔离。研究显示,在RT-PCR阳性的无症状COVID-19病例中,影像学变化明显。目的:本横断面研究的目的是表征尼泊尔一家COVID指定医院无症状rt - pcr阳性患者的胸部CT表现。结果:在43名参与者中,26名(60.5%)的胸部CT扫描结果与COVID -肺炎一致。65%为双侧病灶,77%为多灶性病变。毛玻璃混浊(92%)、混合(毛玻璃混浊及实变)型(30.7%)及单纯实变型(34.6%)是常见的胸部CT表现。CT评分中位数为3.5(四分位范围;2 - 6)。结论:大多数RT-PCR阳性无症状患者存在肺部CT扫描改变,这对确定这些队列的临床状态、预后和长期随访具有重要意义。
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引用次数: 0
Trends and Determinants of Perinatal Mortality in a Tertiary Care Hospital of Nepal 尼泊尔一家三级护理医院围产期死亡率的趋势和决定因素
Pub Date : 2021-02-02 DOI: 10.3126/MJSBH.V20I1.29133
Y. Basaula, R. Paudel, R. Chapagain
Introduction: Perinatal mortality rate (PMR) in Nepal is still very high. In major hospitals of Nepal, it is still ranging from 20 to 30 per thousand births. This study was carried out to review the different aspects of PMR and classifying them and identify the causes of perinatal and neonatal deaths and assessing the need for improvement in quality of pregnancy and newborn care. Methods: It was a retrospective study carried out in Bharatpur Hospital, Chitawan, Nepal. Data of all stillbirths from 22 weeks of pregnancy and neonatal deaths up to seven days of life was taken from monthly perinatal audit and annual mortality review. The data was taken from July 2017 to Jun 2019. All the perinatal deaths were then classified. Results: Over a two year period, there were total 25,977 births and total death was 369. Thus perinatal mortality rate was 12.3 per thousand births. Still births (fresh and macerated) contributed almost 82.4% of the perinatal deaths and neonatal death contributed 17.6% of total deaths. Deaths related to unexplained intrauterine fetal death (IUFD) showed an increasing trend and have increased by more than 20% in past two years from 39.1% to 60.8%. Deaths due to perinatal asphyxia, neonatal sepsis, respiratory distress syndrome and extreme prematurity were increased. Conclusions: PMR over the two years has shown increasing trend at our institute. There is need to improve antenatal, obstetric as well as intra-partum services to further reduce the still birth as well as deaths due to prematurity, RDS, neonatal sepsis and perinatal asphyxia.
引言:尼泊尔的围产期死亡率仍然很高。在尼泊尔的主要医院,这一比例仍然在千分之二十到三十之间。本研究旨在审查PMR的不同方面并对其进行分类,确定围产期和新生儿死亡的原因,并评估提高妊娠和新生儿护理质量的必要性。方法:回顾性研究在尼泊尔奇塔万的巴拉特布尔医院进行。从怀孕22周到新生儿死亡7天的所有死产数据来自每月围产期审计和年度死亡率审查。数据取自2017年7月至2019年6月。然后对所有围产期死亡进行分类。结果:在两年的时间里,共有25977人出生,369人死亡。因此,围产期死亡率为12.3‰。死产(新鲜和浸渍)占围产期死亡的82.4%,新生儿死亡占总死亡的17.6%。与不明原因宫内胎儿死亡(IUFD)相关的死亡呈上升趋势,在过去两年中增加了20%以上,从39.1%增加到60.8%。围产期窒息、新生儿败血症、呼吸窘迫综合征和极度早产导致的死亡增加。结论:近两年来,我院PMR呈上升趋势。需要改善产前、产科和产后服务,以进一步减少早产、RDS、新生儿败血症和围产期窒息造成的死产和死亡。
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引用次数: 2
Pattern of Medicine Prescribing in PHC Facilities before and after earthquake in Nepal 尼泊尔地震前后初级保健机构的用药模式
Pub Date : 2021-02-02 DOI: 10.3126/MJSBH.V20I1.28552
G. Bhuju, K. Kafle, R. R. Prasad, V. Rajbhandari, Gorkha Bahadur Dc, S. B. Karkee, B. Shrestha, Praful Pradhananga

 MJSBH Vol 20 Issue 1 Jan-Jun 2021 !41 Pattern of Medicine Prescribing in PHC Facilities before and after earthquake in Nepal Gajendra Bahadur Bhuju1,2, Kumud Kumar Kafle1,3, Radha Raman Prasad1,4, Vabha Rajbhandari1,5, Gorkha Bahadur DC1,6, Shiba Bahadur Karkee1,2, Bimal Man Shrestha1,7 and Praful Pradhananga1,8 1Pharmaceutical Horizon of Nepal 2Centre Institute of Science and Technology, New Baneshwor, Kathmandu, Nepal 3College of Medicine, Nepalese Army Institute of Health Sciences, Syanobharyang,Kathmandu, Nepal 4Association of Pharmaceutical Producers of Nepal, Nepal 5Sun Pharmaceuticals Limited 6Nepal Ausadhi Limited, Babarmahal, Kathmandu, Nepal 7Canadian Diabetes Association 8Agrata Health Education and Development (AHEAD)-Nepal, Kathmandu, Nepal
41尼泊尔地震前后初级保健机构的药物处方模式Gajendra Bahadur bhuju1,2, Kumud Kumar kafle1,3, Radha Raman prasad1,4, Vabha rajbhandari1,5, Gorkha Bahadur DC1,6, Shiba Bahadur karke1,2, Bimal Man shrestha 1,7和Praful Pradhananga1,8尼泊尔药学视野2尼泊尔加德满都新巴内什霍尔科学技术中心3尼泊尔陆军卫生科学研究所医学学院Syanobharyang,尼泊尔加德满都4尼泊尔药品生产商协会5太阳制药有限公司6尼泊尔Ausadhi有限公司,Babarmahal,尼泊尔加德满都7加拿大糖尿病协会8Agrata健康教育和发展(AHEAD)-尼泊尔,尼泊尔加德满都
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引用次数: 0
Factors Influencing Participation In Professional Developmental Activities Among Nursing Personnel 影响护理人员参与专业发展活动的因素
Pub Date : 2021-02-02 DOI: 10.3126/MJSBH.V20I1.29061
Rojeena Silwal, Sarita Panta
Introduction: Professional Developmental Activities (PDA) are the means to update the health care providers with new knowledge and help them to provide quality care and better patient outcomes. This study aims to determine the factors that influence participation in professional development activities among nursing personnel. Methods: A cross sectional study was conducted among nurses in Tribhuvan University Teaching Hospital, Maharajgung, Kathmandu, Nepal. Simple random sampling technique was used to collect data. Data was collected through self-administered semi-structured questionnaire. The collected data were analysed for descriptive and inferential statistics using SPSS version 20. Results: Total 124 nurses participated in the study. Most (88.7%) were working as a staff nurse. Majority (60.5%) of nurses had participated in PDA within last 12 months. The most common factors which motivated nurses to participate in PDA were family / spouse support and improve knowledge (98.7%). The major hindering factors were shortage of staff (97.9%), and lack of cost (91.8%). Chi-square and Fisher exact tests were used to test the association of selected variables and PDA participation and significant association was seen between participants designation categorised as staff nurse, senior staff nurse and nursing in charge (p < 0.008) and those who were involved in professional developmental activities. Conclusions: Based on findings, the study concluded that there are several factors either hindering or motivating related to work, family, financial, personal and career that contributes to nurses participation in PDA.
简介:专业发展活动(PDA)是向医疗保健提供者提供新知识的手段,帮助他们提供高质量的护理和更好的患者结果。本研究旨在确定影响护理人员参与专业发展活动的因素。方法:对尼泊尔加德满都Maharajgung Tribhuvan大学教学医院的护士进行横断面研究。采用简单的随机抽样技术收集数据。数据是通过自我管理的半结构化问卷收集的。使用SPSS版本20对收集的数据进行描述性和推断统计学分析。结果:共有124名护士参与了这项研究。大多数(88.7%)是一名护士。大多数(60.5%)护士在过去12个月内参加过PDA。促使护士参与PDA的最常见因素是家庭/配偶支持和提高知识(98.7%),卡方检验和Fisher精确检验用于检验所选变量与PDA参与度的相关性,被归类为护士长、高级护士长和护理主管的参与者与参与专业发展活动的参与者之间存在显著相关性(p<0.008)。结论:根据研究结果,该研究得出结论,有几个因素阻碍或激励护士参与PDA,这些因素与工作、家庭、经济、个人和职业有关。
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引用次数: 2
Job Satisfaction among Nurses Working in a Tertiary Level Government Hospital 三级政府医院护士工作满意度调查
Pub Date : 2021-02-02 DOI: 10.3126/MJSBH.V20I1.28777
Ajanta Singh, Roshi Chakradhar, Nibaran Joshi
This work is licensed under creative common license: http://creativecommons.org/licenses/by-nc-nd/4.0/ © MJSBH 2020 ABSTRACT Introduction: Job satisfaction refers to the employees having a feeling of job stability, career growth and a comfortable work life balance which implies that the employee is having satisfaction at job and the individual’s expectations are met. Job satisfaction is one of the most important factors that determine efficiency and productivity of human resources. It is vital to increase nurse’s job satisfaction to improve patients care quality and ensure adequate nursing workforce which helps in the development of effective strategies to address the nursing shortage and increase the quality of patient care. The objective of this study was to assess the level of job satisfaction among nurses working in the government hospital. Methods: A descriptive cross-sectional design was adopted. All the nursing staffs working in Kanti Children’s Hospital, Kathmandu, Nepal were the study population and the total sample size was 81, selected using stratified random sampling techniques from different wards. The information was collected by using self-administered structured questionnaire. Level of job satisfaction was assessed by using 5point Likert Scale. The collected data were entered into SPSS version 16 and were analysed using descriptive and inferential statistics. Results: The study findings showed that almost half (46.9%) of the respondents were satisfied with their current job. The satisfaction mean score obtained by work itself and nursing practice was (23.35 + 4.25) followed by advancement opportunity with mean value (20.44 + 4.97). Similarly, the satisfaction score obtained for recognition and reward (6.80 + 2.62) followed by participation in decision making with mean value (9.45 + 2.24). There was a statistical association between the level of job satisfaction and ethnicity (p = 0.41), marital status (p = 0.005), professional qualification (p = 0.001) and work experience (p = 0.002) of the respondents.
摘要简介:工作满意度是指员工对工作稳定、职业发展和舒适的工作生活平衡的感觉,这意味着员工对工作有满意度,个人的期望得到满足。工作满意度是决定人力资源效率和生产力的最重要因素之一。提高护士的工作满意度对提高患者护理质量和保证足够的护理队伍至关重要,这有助于制定有效的策略来解决护理短缺问题,提高患者护理质量。本研究的目的是评估公立医院护士的工作满意度。方法:采用描述性横断面设计。所有在尼泊尔加德满都Kanti儿童医院工作的护理人员为研究人群,总样本量为81人,采用分层随机抽样技术从不同病房选择。采用自我管理的结构化问卷收集信息。工作满意度采用李克特5点量表进行评估。将收集到的数据输入SPSS version 16,并使用描述性统计和推理统计进行分析。结果:调查结果显示,近一半(46.9%)的受访者对目前的工作感到满意。工作本身满意度和护理实践满意度平均得分为(23.35 + 4.25)分,其次是晋升机会满意度平均得分为(20.44 + 4.97)分。同样,对认可和奖励的满意度得分为6.80 + 2.62,其次是参与决策,平均得分为9.45 + 2.24。工作满意度水平与被调查者的种族(p = 0.41)、婚姻状况(p = 0.005)、职业资格(p = 0.001)和工作经验(p = 0.002)有统计学相关性。
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引用次数: 0
Role of Breast Ultrasonography in Adding Diagnostic Value in Case of Dense Breasts Detected by Mammography 乳腺超声对乳腺x线摄影检查致密性乳房的诊断价值
Pub Date : 2021-02-02 DOI: 10.3126/MJSBH.V20I1.31025
S. Panta, R. Shahi, Sujit Panta, Binamra Basnet, Kalpana Rai, Neeraj Basanta Tulachan
Introduction: Mammography is a simple and effective tool in early detection of breast lesions. However its sensitivity is less in dense breast. The aim of the study is to see whether addition of ultrasonography adds on to the diagnostic value by finding more breast lesions in evaluation of mammographic dense breasts or not. Methods: The hospital data of all the patients who underwent mammography in the Department of Radiology of Shree Birendra Hospital, Kathmandu over a period of two and a half years from November 2017 to April 2020 were retrieved and retrospectively analyzed. The mammographic findings of patients with dense breast were compared with the corroborative ultrasonographic findings. Discrepancy in positive findings between the two imaging modalities was studied. Results: Out of 536 patients studied, 238 patients had mammographic dense breast. Comparative study showed 82 cases with positive findings on mammography alone, compared to 114 cases with positive findings on combined mammography and ultrasonography with p-value < 0.05 which is statistically significant. Conclusions: Ultrasonography is a useful additional imaging modality in evaluation of mammographic dense breast by finding more breast lesions compared to Mammography alone.
简介:乳房x光检查是早期发现乳腺病变的一种简单有效的工具。但在致密乳腺中其敏感性较低。本研究的目的是观察超声检查的增加是否增加了乳房致密性乳房的诊断价值,从而发现更多的乳腺病变。方法:检索加德满都Shree Birendra医院放射科2017年11月至2020年4月2年半期间所有接受乳房x光检查的患者的医院资料并进行回顾性分析。将致密乳腺患者的乳腺x线检查结果与确证性超声检查结果进行比较。研究了两种成像方式之间阳性结果的差异。结果:在536例患者中,238例患者有乳腺致密。对比研究显示,单独x光检查阳性82例,联合x光检查阳性114例,p值< 0.05,差异有统计学意义。结论:超声检查是一种有用的附加成像方式,可以发现更多的乳腺病变,与单独的乳房x光检查相比。
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引用次数: 0
Epidemiology, Clinico-radiological Profile and Management of Hepatocellular Carcinoma in a Tertiary Care Center in Nepal 尼泊尔一家三级医疗中心肝细胞癌的流行病学、临床放射学特征和管理
Pub Date : 2021-02-02 DOI: 10.3126/MJSBH.V20I1.32256
R. Deo, P. Chitalkar, Srijan Malla, I. Kc, Binod Karki, R. Thapa
Introduction: Hepatocellular Carcinoma (HCC) is a common malignancy of gastrointestinal tract presenting in clinical practice. The common etiologies are hepatitis B virus (HBV), hepatitis C virus (HCV) and alcohol consumption. Treatment of HCC is multimodality based on Barcelona Clinic Liver Cancer (BCLC) staging system. The aim of the article is to study the demographic, clinico-radiological profile and treatment patterns of HCC patients. Methods: This is a retrospective cross sectional study of patients diagnosed as HCC at Shree Birendra Hospital, Chhauni, Kathmandu, Nepal from April 2017 to March 2020. The study was approved by Institutional Review Committee. Data were collected for demography, clinical feature, histology, HBsAg status, serum AFP values, radiological findings and treatment details from hospital record. Data were analysed using Excel 2010 and SPSS v 21. Results: Total of 36 patients diagnosed with HCC were included for analysis. There was a male predominance (72.22%) and the mean age was 66.75 ± 12.02 years. Pain abdomen and jaundice were present in 63.89% and 38.89% respectively at presentation and features of chronic liver disease (CLD) were evident in 83.33%. HBsAg was present in 44.44% of HCC. Location of tumour was primarily in right lobe (80.56%) and size of lesion varied greatly. Tissue diagnosis was obtained in 52.78% patients. Chemotherapy option was limited to Sorafenib. Conclusions: HCC is more prevalent in older males. The common modes of presentation were pain abdomen and jaundice. Most of the HCC had underlying CLD and were advanced. Sorafenib was the mainstay of treatment in advanced HCC.
前言:肝细胞癌是临床上常见的胃肠道恶性肿瘤。常见的病因是乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)和饮酒。HCC的治疗是基于巴塞罗那临床癌症(BCLC)分期系统的多模式治疗。本文的目的是研究HCC患者的人口统计学、临床放射学特征和治疗模式。方法:这是对2017年4月至2020年3月在尼泊尔加德满都乔尼Shree Birendra医院诊断为HCC的患者进行的回顾性横断面研究。该研究得到了机构审查委员会的批准。从医院记录中收集人口统计学、临床特征、组织学、HBsAg状态、血清AFP值、放射学检查结果和治疗细节的数据。使用Excel 2010和SPSS v21对数据进行分析。结果:共纳入36例诊断为HCC的患者进行分析。男性占优势(72.22%),平均年龄66.75±12.02岁。腹痛和黄疸分别占63.89%和38.89%,慢性肝病(CLD)特征明显者占83.33%,HBsAg阳性者占44.44%。肿瘤主要位于右叶(80.56%),病变大小变化较大。52.78%的患者获得了组织诊断。化疗选择仅限于索拉非尼。结论:HCC在老年男性中更为普遍。常见的表现方式是腹部疼痛和黄疸。大多数HCC有潜在的CLD,并且是晚期的。索拉非尼是治疗晚期HCC的主要药物。
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引用次数: 2
期刊
Medical Journal of Shree Birendra Hospital
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