Navnee Jain, Y. Marfatia, Preksha Panthesh Jinwala, Hiral Patel
Epidermolysis bullosa pruriginosa (EBP) is a rare inherited and distinctive clinical subtype of dystrophic epidermolysis bullosa. Here is a pediatric case of EBP with extremely pruritic lesions on extensor aspect of limbs and back, where the main modality of treatment given was topical retinoid (tazarotene) and oral retinoid (Acitretin), to which she had responded well clinically as well as symptomatically.
{"title":"Epidermolysis Bullosa Pruriginosa Treated with Acitretin","authors":"Navnee Jain, Y. Marfatia, Preksha Panthesh Jinwala, Hiral Patel","doi":"10.25259/ijpgd_8_2023","DOIUrl":"https://doi.org/10.25259/ijpgd_8_2023","url":null,"abstract":"Epidermolysis bullosa pruriginosa (EBP) is a rare inherited and distinctive clinical subtype of dystrophic epidermolysis bullosa. Here is a pediatric case of EBP with extremely pruritic lesions on extensor aspect of limbs and back, where the main modality of treatment given was topical retinoid (tazarotene) and oral retinoid (Acitretin), to which she had responded well clinically as well as symptomatically.","PeriodicalId":339918,"journal":{"name":"Indian Journal of Postgraduate Dermatology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124398925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Kavya, Mohammed Salman Hyder, Keshavmurthy A Adya, A. Inamadar
{"title":"Dermoscopy-assisted Radiofrequency-facilitated Extraction of a Live Tick","authors":"R. Kavya, Mohammed Salman Hyder, Keshavmurthy A Adya, A. Inamadar","doi":"10.25259/ijpgd_30_2023","DOIUrl":"https://doi.org/10.25259/ijpgd_30_2023","url":null,"abstract":"","PeriodicalId":339918,"journal":{"name":"Indian Journal of Postgraduate Dermatology","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132503197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Monkeypox: Anecdotes from the UAE","authors":"S. Pillai","doi":"10.25259/ijpgd_14_2023","DOIUrl":"https://doi.org/10.25259/ijpgd_14_2023","url":null,"abstract":"","PeriodicalId":339918,"journal":{"name":"Indian Journal of Postgraduate Dermatology","volume":"198 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132868868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Jagadeesan, Prasanna Duraisamy, V. Panicker, Gopikrishnan Anjaneyan, Lekshmi Sajini, Sreedevan Velayudhan, Jacob Thomas
Erythrokeratodermas are genodermatoses of keratinisation which usually presents in infancy. Erythrokeratoderma en cocardes is a rare variant of erythrokeratoderma which present as polycyclic hyperkeratotic plaques with a peripheral desquamation, forming a concentric appearance termed ‘en cocarde’. Here, we report a case of erythrokeratoderma en cocardes with onset in childhood showing excellent response after 2 months of acitretin therapy.
{"title":"Childhood Onset Erythrokeratoderma En Cocardes Treated with Oral Acitretin","authors":"S. Jagadeesan, Prasanna Duraisamy, V. Panicker, Gopikrishnan Anjaneyan, Lekshmi Sajini, Sreedevan Velayudhan, Jacob Thomas","doi":"10.25259/ijpgd_1_2022","DOIUrl":"https://doi.org/10.25259/ijpgd_1_2022","url":null,"abstract":"Erythrokeratodermas are genodermatoses of keratinisation which usually presents in infancy. Erythrokeratoderma en cocardes is a rare variant of erythrokeratoderma which present as polycyclic hyperkeratotic plaques with a peripheral desquamation, forming a concentric appearance termed ‘en cocarde’. Here, we report a case of erythrokeratoderma en cocardes with onset in childhood showing excellent response after 2 months of acitretin therapy.","PeriodicalId":339918,"journal":{"name":"Indian Journal of Postgraduate Dermatology","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134646294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Circumscribed Translucent Papule on the Eyelid","authors":"Keshavmurthy A Adya, A. Inamadar","doi":"10.25259/ijpgd_20_2023","DOIUrl":"https://doi.org/10.25259/ijpgd_20_2023","url":null,"abstract":"","PeriodicalId":339918,"journal":{"name":"Indian Journal of Postgraduate Dermatology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130269601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erythematous Plaques on the Extensors of the Extremities in a Middle-aged Female","authors":"Molisha Bhandari, G. Khullar, Shruti Sharma","doi":"10.25259/ijpgd_6_2023","DOIUrl":"https://doi.org/10.25259/ijpgd_6_2023","url":null,"abstract":"","PeriodicalId":339918,"journal":{"name":"Indian Journal of Postgraduate Dermatology","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115338057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A 13-year-old boy presented with multiple transient painless swellings over the body for the past 6 months. Lesions would persist for 6–8 weeks and spontaneously resolve leaving behind discolouration and altered skin texture. Clinical examination revealed a single soft, non-tender mobile nodule of 2 × 2 cm over left arm, along with multiple discrete well defined post-inflammatory hypopigmented patches with hyperpigmented scaly papules over the arms, thighs and trunk. Skin biopsy showed lobular panniculitis composed of lymphoid cells, histiocytes and plasma cells with characteristic rimming of fat cells by lymphoid cells suggestive of cytophagic histiocytic panniculitis. Immunohistochemistry showed positive CD3, CD5, CD7 and CD8, negative CD20, CD4, CD56, Ki67 – 75–80%, CD68 highlighting the histiocytes and C30 negative. Positron emission tomography–magnetic resonance imaging showed multiple fluorodeoxyglucose (FDG) avid cutaneous and subcutaneous nodules throughout the body and minimally FDG avid axillary and inguinal lymph nodes. Thereby, a final diagnosis of subcutaneous panniculitis like T-cell lymphoma was concluded. Our patient was started on tapering dose of oral prednisolone and cyclosporine, following which the lesions significantly improved.
{"title":"Intriguing Subcutaneous Nodules – A Panic-Stricken Panniculitis","authors":"S. Jagadeesan, Radhika Krishna, M. Eapen","doi":"10.25259/ijpgd_23_2022","DOIUrl":"https://doi.org/10.25259/ijpgd_23_2022","url":null,"abstract":"A 13-year-old boy presented with multiple transient painless swellings over the body for the past 6 months. Lesions would persist for 6–8 weeks and spontaneously resolve leaving behind discolouration and altered skin texture. Clinical examination revealed a single soft, non-tender mobile nodule of 2 × 2 cm over left arm, along with multiple discrete well defined post-inflammatory hypopigmented patches with hyperpigmented scaly papules over the arms, thighs and trunk. Skin biopsy showed lobular panniculitis composed of lymphoid cells, histiocytes and plasma cells with characteristic rimming of fat cells by lymphoid cells suggestive of cytophagic histiocytic panniculitis. Immunohistochemistry showed positive CD3, CD5, CD7 and CD8, negative CD20, CD4, CD56, Ki67 – 75–80%, CD68 highlighting the histiocytes and C30 negative. Positron emission tomography–magnetic resonance imaging showed multiple fluorodeoxyglucose (FDG) avid cutaneous and subcutaneous nodules throughout the body and minimally FDG avid axillary and inguinal lymph nodes. Thereby, a final diagnosis of subcutaneous panniculitis like T-cell lymphoma was concluded. Our patient was started on tapering dose of oral prednisolone and cyclosporine, following which the lesions significantly improved.","PeriodicalId":339918,"journal":{"name":"Indian Journal of Postgraduate Dermatology","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131882760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bhargavi Mayakuntla, M. Susmitha, S. Ravi, Indira Bonthu, V. Anitha, V. Satyanarayana
Pyogenic granuloma (PG) is a common, benign lesion of vascular origin. It may rapidly grow in response to an unknown stimulus that triggers endothelial proliferation. The treatment of PG using sclerosing agents is a novel approach to overcome drawbacks associated with other procedures. The crucial purpose of this study is to evaluate the efficacy and safety of detergent sclerosant, sodium tetradecyl sulphate (STS) in the management of PG. A total of 18 patients with PG, attending dermatology venereology and leprosy (DVL) outpatient department (OPD) were treated with sclerotherapy after obtaining written and informed consent. STS solution (3%, 30 mg/mL) was injected with insulin syringe slowly into the lesion until the lesion blanched up to maximum amount of 0.3 mL. Injection was repeated every week until resolution or up to maximum of 4 doses. Follow-up evaluation was performed monthly, up to 3 months. In our study, complete resolution was seen in all the patients. No complication occurred after injection. All the patients were followed up for 3 months and none of the lesions recurred over this duration. Sclerotherapy is effective and safe in the treatment of PG without any recurrence. This approach may become a first-line therapy option for PG, especially in cases of recurrent PG associated with bleeding, and in lesions over surgically inaccessible areas.
{"title":"Sclerotherapy in Pyogenic Granuloma: An Open Uncontrolled Trial","authors":"Bhargavi Mayakuntla, M. Susmitha, S. Ravi, Indira Bonthu, V. Anitha, V. Satyanarayana","doi":"10.25259/ijpgd_2_2023","DOIUrl":"https://doi.org/10.25259/ijpgd_2_2023","url":null,"abstract":"\u0000\u0000Pyogenic granuloma (PG) is a common, benign lesion of vascular origin. It may rapidly grow in response to an unknown stimulus that triggers endothelial proliferation. The treatment of PG using sclerosing agents is a novel approach to overcome drawbacks associated with other procedures. The crucial purpose of this study is to evaluate the efficacy and safety of detergent sclerosant, sodium tetradecyl sulphate (STS) in the management of PG.\u0000\u0000\u0000\u0000A total of 18 patients with PG, attending dermatology venereology and leprosy (DVL) outpatient department (OPD) were treated with sclerotherapy after obtaining written and informed consent. STS solution (3%, 30 mg/mL) was injected with insulin syringe slowly into the lesion until the lesion blanched up to maximum amount of 0.3 mL. Injection was repeated every week until resolution or up to maximum of 4 doses. Follow-up evaluation was performed monthly, up to 3 months.\u0000\u0000\u0000\u0000In our study, complete resolution was seen in all the patients. No complication occurred after injection. All the patients were followed up for 3 months and none of the lesions recurred over this duration.\u0000\u0000\u0000\u0000Sclerotherapy is effective and safe in the treatment of PG without any recurrence. This approach may become a first-line therapy option for PG, especially in cases of recurrent PG associated with bleeding, and in lesions over surgically inaccessible areas.\u0000","PeriodicalId":339918,"journal":{"name":"Indian Journal of Postgraduate Dermatology","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129366230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Monkeypox is a zoonotic disease which mimics smallpox very closely in morphology with presence of deep seated umbilicated vesicles, pustules and erosions going through various stages of evolution. However, sexual transmission has now been recognized as another mode of transmission. In almost all cases where sexual transmission was suspected, it was observed that the typical umbilicated vesicles and pustules were limited around the mouth, pubic and perianal area with mucosal erosions and crusted lesions around these sites (areas of skin to skin sexual contact). Viremia is seen to be more severe in receptive anal intercourse due to greater trauma to the mucosa, with a greater clustering of cases in homosexual and bisexual males. It was observed that people living with HIV had a greater prevalence of monkeypox and the cutaneous lesions tended to be more severe. The best way to prevent transmission is abstinence from any kind of intercourse until the lesions and fever subside.
{"title":"Sexual Transmission of Monkeypox Virus","authors":"P. Agarwal, Dhruv Gupta","doi":"10.25259/ijpgd_24_2022","DOIUrl":"https://doi.org/10.25259/ijpgd_24_2022","url":null,"abstract":"Monkeypox is a zoonotic disease which mimics smallpox very closely in morphology with presence of deep seated umbilicated vesicles, pustules and erosions going through various stages of evolution. However, sexual transmission has now been recognized as another mode of transmission. In almost all cases where sexual transmission was suspected, it was observed that the typical umbilicated vesicles and pustules were limited around the mouth, pubic and perianal area with mucosal erosions and crusted lesions around these sites (areas of skin to skin sexual contact). Viremia is seen to be more severe in receptive anal intercourse due to greater trauma to the mucosa, with a greater clustering of cases in homosexual and bisexual males. It was observed that people living with HIV had a greater prevalence of monkeypox and the cutaneous lesions tended to be more severe. The best way to prevent transmission is abstinence from any kind of intercourse until the lesions and fever subside.","PeriodicalId":339918,"journal":{"name":"Indian Journal of Postgraduate Dermatology","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115362922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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