Pub Date : 2008-10-01DOI: 10.11405/NISSHOSHI.105.1482
陽子 新井, 恒男 小山, 欣一 堀田, 彰寿 友利, 佳典 宮田
: 5-Fluorouracil(5-FU)and cis-dichlorodiammineplatinum(CDDP)combined with 60Gy of radiation was administered to a 65-year-old man with advanced esophageal cancer complicated with chronic renal failure treated with hemodialysis(HD). Continuous infusion of 5-FU 680mg/m(2) on Days 1-5 and 8-12, and drip infusion of CDDP 40mg/m(2) on Days 1 and 8 were administered twice with a 5-week interval. The CDDP dosage was reduced to 40% and HD was started 30 minutes after CDDP administration. Concurrent radiotherapy was started on Day 1 at 2Gy/d for 5d/week. The concentration of both free CDDP and total CDDP was measured using the atomic absorption method after the second treatment period. The area under the curve(AUC)of free CDDP was 3.3microg x h/ml. Both Grade 4 anemia and Grade 3 leukopenia were observed, but the renal failure did not progress. All toxicities were tolerable and the CDDP dose reduction and HD method were appropriate for the patient.
5-氟尿嘧啶(5-FU)和顺式二氯二胺铂(CDDP)联合60Gy放射治疗1例65岁晚期食管癌合并慢性肾衰竭经血液透析(HD)治疗的男性。5-FU连续滴注680mg/m(2)于第1-5天、第8-12天，CDDP滴注40mg/m(2)于第1天、第8天，两次，间隔5周。CDDP给药后30min, CDDP剂量降至40%，开始HD治疗。第1天开始同步放疗，放疗剂量为2Gy/d，持续5d/周。第二次处理后，用原子吸收法测定游离CDDP和总CDDP的浓度。游离CDDP曲线下面积(AUC)为3.3 μ g × h/ml。观察到4级贫血和3级白细胞减少，但肾功能衰竭没有进展。所有毒副反应均可耐受，CDDP减量和HD方法适用于患者。
{"title":"血液透析中の慢性腎不全患者に合併した進行食道癌に対して5-Fluorouracil+cis-dichlorodiammineplatinum+放射線照射同時併用療法が有効であった1例","authors":"陽子 新井, 恒男 小山, 欣一 堀田, 彰寿 友利, 佳典 宮田","doi":"10.11405/NISSHOSHI.105.1482","DOIUrl":"https://doi.org/10.11405/NISSHOSHI.105.1482","url":null,"abstract":": 5-Fluorouracil(5-FU)and cis-dichlorodiammineplatinum(CDDP)combined with 60Gy of radiation was administered to a 65-year-old man with advanced esophageal cancer complicated with chronic renal failure treated with hemodialysis(HD). Continuous infusion of 5-FU 680mg/m(2) on Days 1-5 and 8-12, and drip infusion of CDDP 40mg/m(2) on Days 1 and 8 were administered twice with a 5-week interval. The CDDP dosage was reduced to 40% and HD was started 30 minutes after CDDP administration. Concurrent radiotherapy was started on Day 1 at 2Gy/d for 5d/week. The concentration of both free CDDP and total CDDP was measured using the atomic absorption method after the second treatment period. The area under the curve(AUC)of free CDDP was 3.3microg x h/ml. Both Grade 4 anemia and Grade 3 leukopenia were observed, but the renal failure did not progress. All toxicities were tolerable and the CDDP dose reduction and HD method were appropriate for the patient.","PeriodicalId":341053,"journal":{"name":"The Japanese journal of gastro-enterology","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132020177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
: The patients was a 54-year-old woman. In the liver, a high-echo phyma was detected. The lesion increased from 5 to 23mm over 2 years and 4 months. On CT and MRI, it was difficult to differentiate the phyma from hepatocellular carcinoma. However, angiography revealed early outflow to the hepatic vein. In the late CTHA phase of angio-CT, there was no ring-like dark staining reaction (corona), as observed in hepatocellular carcinoma patients, outside the tumor. Hepatectomy was performed, suggesting angiomyolipoma. The course of enlargement could be followed-up, and we present findings that may be useful for differentiating this tumor from hepatocellular carcinoma.
{"title":"増大の経過を確認できた肝血管筋脂肪腫(angiomyolipoma: AML）の1例","authors":"憲昭 采田, 治男 今村, 修治 多田, 上川 健太郎, 康一 工藤, 秀人 近澤, 秀一 宮瀬, 博信 須古, 和彦 廣田, 譲治 浦田, 克彦 満崎, 神尾 多喜浩","doi":"10.11405/NISSHOSHI.105.1375","DOIUrl":"https://doi.org/10.11405/NISSHOSHI.105.1375","url":null,"abstract":": The patients was a 54-year-old woman. In the liver, a high-echo phyma was detected. The lesion increased from 5 to 23mm over 2 years and 4 months. On CT and MRI, it was difficult to differentiate the phyma from hepatocellular carcinoma. However, angiography revealed early outflow to the hepatic vein. In the late CTHA phase of angio-CT, there was no ring-like dark staining reaction (corona), as observed in hepatocellular carcinoma patients, outside the tumor. Hepatectomy was performed, suggesting angiomyolipoma. The course of enlargement could be followed-up, and we present findings that may be useful for differentiating this tumor from hepatocellular carcinoma.","PeriodicalId":341053,"journal":{"name":"The Japanese journal of gastro-enterology","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116563175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We report three cases of gastrointestinal stromal tumor (GIST) with delayed bone metastasis at least four years after initial surgery. One small intestinal and two rectal GISTs were all considered as high-risk according to the classification based on tumor size and mitotic count. GIST usually metastasizes to the liver and peritoneum, however bone metastasis should be considered in the patients with long prognosis.
{"title":"骨転移をきたしたgastrointestinal stromal tumor(GIST）3症例の検討","authors":"隆彦 中嶋, 重治 三輪, 孝将 安藤, 一樹 山田, 孝子 宮嵜, 歩 細川, 俊彦 工藤, 寛 野澤, 基一 前田, 敏郎 杉山","doi":"10.11405/NISSHOSHI.105.836","DOIUrl":"https://doi.org/10.11405/NISSHOSHI.105.836","url":null,"abstract":"We report three cases of gastrointestinal stromal tumor (GIST) with delayed bone metastasis at least four years after initial surgery. One small intestinal and two rectal GISTs were all considered as high-risk according to the classification based on tumor size and mitotic count. GIST usually metastasizes to the liver and peritoneum, however bone metastasis should be considered in the patients with long prognosis.","PeriodicalId":341053,"journal":{"name":"The Japanese journal of gastro-enterology","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132230261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
: Von Hippel-Lindau disease (VHL disease) is an inherited neoplasia syndrome. VHL disease which frequently complicates pancreatic lesions is rarely diagnosed by existence of pancreatic involvements. We report two cases of VHL disease with pancreatic lesions. The first patient was a 40-year-old woman. Adrenal pheochromocytoma, spinal hemangioblastoma and pancreatic endocrine tumor were resected. The second case was a 68-year-old woman with past surgical histories included cerebellar and spinal hemangioblastoma. Subtotal pancreatectomy was performed for multiple serous cystadenoma. IPMN which has been never reported as pancreatic involvement of VHL disease were documented by imaging diagnosis in the first case, and by histological examination in the second case. We considered VHL disease from coexistent multiple tumors include pancreatic involvements and finally diagnosed by genetic examination in both cases. Care should be taken regarding the patient's right for treatment against for the genetic disease. We hold a genetic conference composed of multidisciplinary team. Consequently we detected another VHL disease patient from patient's family.
Von Hippel-Lindau病(VHL病)是一种遗传性肿瘤综合征。VHL疾病常并发胰腺病变，很少因累及胰腺而被诊断。我们报告两例VHL疾病伴胰腺病变。第一位患者是一位40岁的女性。切除肾上腺嗜铬细胞瘤、脊髓成血管细胞瘤和胰腺内分泌肿瘤。第二例为68岁女性，既往手术史包括小脑和脊柱血管母细胞瘤。多发性浆液性囊腺瘤行胰次全切除术。IPMN从未被报道为VHL疾病的胰腺累及，在第一例中通过影像学诊断，在第二例中通过组织学检查。我们认为VHL疾病来自共存的多个肿瘤，包括胰腺受累，并最终通过遗传检查诊断。应注意病人对遗传疾病的治疗权利。我们召开了由多学科小组组成的遗传学会议。因此，我们从患者家庭中发现了另一名VHL患者。
{"title":"Von Hippel-Lindau病に合併した膵腫瘍(内分泌腫瘍，漿液性嚢胞腺腫）の2切除例","authors":"秀則 唐崎, 彰 石崎, 伸幸 柳川, 靖弘 中野, 順平 笹島, 裕輔 水上, 誠志 丹野, 良彦 徳差, 斉之 三代川, 充裕 小原, 順一 後藤, 修一 紀野, 透 河野, 眞一 葛西","doi":"10.11405/NISSHOSHI.105.725","DOIUrl":"https://doi.org/10.11405/NISSHOSHI.105.725","url":null,"abstract":": Von Hippel-Lindau disease (VHL disease) is an inherited neoplasia syndrome. VHL disease which frequently complicates pancreatic lesions is rarely diagnosed by existence of pancreatic involvements. We report two cases of VHL disease with pancreatic lesions. The first patient was a 40-year-old woman. Adrenal pheochromocytoma, spinal hemangioblastoma and pancreatic endocrine tumor were resected. The second case was a 68-year-old woman with past surgical histories included cerebellar and spinal hemangioblastoma. Subtotal pancreatectomy was performed for multiple serous cystadenoma. IPMN which has been never reported as pancreatic involvement of VHL disease were documented by imaging diagnosis in the first case, and by histological examination in the second case. We considered VHL disease from coexistent multiple tumors include pancreatic involvements and finally diagnosed by genetic examination in both cases. Care should be taken regarding the patient's right for treatment against for the genetic disease. We hold a genetic conference composed of multidisciplinary team. Consequently we detected another VHL disease patient from patient's family.","PeriodicalId":341053,"journal":{"name":"The Japanese journal of gastro-enterology","volume":"102 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125283604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-04-05DOI: 10.11405/NISSHOSHI.105.550
R. Kita, M. Nakatsuji, N. Nishijima, Hisatoku Kawakami, Kiyoaki Hatano, H. Matsuo, Sumio Saito, Atsuyuki Ikeda, Akihiro Nasu, Hiroki Nishikawa, Toru Kimura, Y. Osaki, O. Nakashima
A hepatic nodule was detected in segment 5/6 on abdominal US study in a 28 year-old male. The nodule was 7cm in diameter and the early phase of contrasted US, CT and MRI images showed spoke-wheel like vessels radiating from the center. No defect images were observed on postvascular phase contrasted US and SPIO MRI, which indicated the presence of Kupffer cells in the nodule. The nodule was diagnosed as a focal nodular hyperplasia (FNH) based on histological findings. The late phase of single level dynamic CT during hepatic arteriography (CTHA) showed corona enhancement of the nodule, which is considered to be characteristic of hypervascular metastatic liver tumors, hyperplastic nodules and HCCs. In our case, the drainage flow from the nodule may have been visualized as corona enhancement via the pathway from the sinusoid in the nodular periphery to the one in the adjacent and contiguous parenchyma.
{"title":"コロナ様濃染を認めた限局性結節性過形成(FNH)の1症例","authors":"R. Kita, M. Nakatsuji, N. Nishijima, Hisatoku Kawakami, Kiyoaki Hatano, H. Matsuo, Sumio Saito, Atsuyuki Ikeda, Akihiro Nasu, Hiroki Nishikawa, Toru Kimura, Y. Osaki, O. Nakashima","doi":"10.11405/NISSHOSHI.105.550","DOIUrl":"https://doi.org/10.11405/NISSHOSHI.105.550","url":null,"abstract":"A hepatic nodule was detected in segment 5/6 on abdominal US study in a 28 year-old male. The nodule was 7cm in diameter and the early phase of contrasted US, CT and MRI images showed spoke-wheel like vessels radiating from the center. No defect images were observed on postvascular phase contrasted US and SPIO MRI, which indicated the presence of Kupffer cells in the nodule. The nodule was diagnosed as a focal nodular hyperplasia (FNH) based on histological findings. The late phase of single level dynamic CT during hepatic arteriography (CTHA) showed corona enhancement of the nodule, which is considered to be characteristic of hypervascular metastatic liver tumors, hyperplastic nodules and HCCs. In our case, the drainage flow from the nodule may have been visualized as corona enhancement via the pathway from the sinusoid in the nodular periphery to the one in the adjacent and contiguous parenchyma.","PeriodicalId":341053,"journal":{"name":"The Japanese journal of gastro-enterology","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116771357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-03-01DOI: 10.11405/NISSHOSHI.105.367
俊明 平澤, 新吾 浅原, 聡 藤崎, 賢輔 倉岡, 浩一 高野, 明徳 亀井, 功遺 猪狩
: We reviewed the effects and complications of transcatheter arterial chemoembolization (TACE), using degradable starch microspheres (DSM) in eight patients with hepatic metastases from gastric cancer. The rate of complete remission (CR) +partial remission (PR) was 62.5%, and the actual survival rates at one and two years post-treatment were 87.5%, and 52.5% respectively. The median survival time was 36.1 months. Almost all side effects were acceptable but in one case, we observed liver abscess. From this study, we suggest that DSM-TACE might be a safe and effective multimodal treatment for metastatic liver tumors in patients with gastric cancer.
{"title":"胃癌肝転移に対するDSM併用動注化学療法(DSM-TACE）の検討","authors":"俊明 平澤, 新吾 浅原, 聡 藤崎, 賢輔 倉岡, 浩一 高野, 明徳 亀井, 功遺 猪狩","doi":"10.11405/NISSHOSHI.105.367","DOIUrl":"https://doi.org/10.11405/NISSHOSHI.105.367","url":null,"abstract":": We reviewed the effects and complications of transcatheter arterial chemoembolization (TACE), using degradable starch microspheres (DSM) in eight patients with hepatic metastases from gastric cancer. The rate of complete remission (CR) +partial remission (PR) was 62.5%, and the actual survival rates at one and two years post-treatment were 87.5%, and 52.5% respectively. The median survival time was 36.1 months. Almost all side effects were acceptable but in one case, we observed liver abscess. From this study, we suggest that DSM-TACE might be a safe and effective multimodal treatment for metastatic liver tumors in patients with gastric cancer.","PeriodicalId":341053,"journal":{"name":"The Japanese journal of gastro-enterology","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117007328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We report a 52-year-old patient with a small hepatic mass which was ultrasonographically anechoic with scattered high echoic spots, and appearing slightly hyperattenuating relative to the surrounding parenchyma on unenhanced CT scans. Laparotomy revealed that the lesion was a unilocular cyst containing a mucinous fluid. The histologic diagnosis was ciliated hepatic foregut cyst (CHFC). The CHFC is a rare congenital cystic tumor which derives from the embryologic foregut. Up to 2006, only 24 cases, including our case, had been reported in Japan. The patients were 13 men and 11 women, aged between 41 years and 79 years. All of the lesions were solitary and unilocular. In 22 cases, the CHFC was located in the medial segment of the left lobe, mostly just beneath the hepatic surface. In all 24 Japanese cases, the cystic wall was benign histologically. However, reports of 3 malignant cases overseas indicates we should treat this disease cautiously.
{"title":"線毛性前腸性肝嚢胞(ciliated hepatic foregut cyst）の1例-本邦報告例24例の検討-","authors":"智彦 万波, 嘉洋 大藤, 恵子 藤原, 勝弘 江野村, 徹哉 太田, 浩範 國末, 修一 野村, 香織 江口, 小田 和歌子, 一郎 山鳥, 晴弘 山下","doi":"10.11405/NISSHOSHI.105.235","DOIUrl":"https://doi.org/10.11405/NISSHOSHI.105.235","url":null,"abstract":"We report a 52-year-old patient with a small hepatic mass which was ultrasonographically anechoic with scattered high echoic spots, and appearing slightly hyperattenuating relative to the surrounding parenchyma on unenhanced CT scans. Laparotomy revealed that the lesion was a unilocular cyst containing a mucinous fluid. The histologic diagnosis was ciliated hepatic foregut cyst (CHFC). The CHFC is a rare congenital cystic tumor which derives from the embryologic foregut. Up to 2006, only 24 cases, including our case, had been reported in Japan. The patients were 13 men and 11 women, aged between 41 years and 79 years. All of the lesions were solitary and unilocular. In 22 cases, the CHFC was located in the medial segment of the left lobe, mostly just beneath the hepatic surface. In all 24 Japanese cases, the cystic wall was benign histologically. However, reports of 3 malignant cases overseas indicates we should treat this disease cautiously.","PeriodicalId":341053,"journal":{"name":"The Japanese journal of gastro-enterology","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115860932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-12-05DOI: 10.11405/NISSHOSHI.104.1728
Koichi Takahashi, Yoshihide Otani, Nobuji Ogawa, Akihiro Yasumoto, A. Takeda, Mitsuo Miyazawa, Nozomi Shinozuka, Isamu Koyama, S. Arai, Shinichi Ota, Shin-ichi Ban
A 52-year-old man undergoing distal gastrectomy for gastric cancer in July 1998 was found to have a 0-IIa type gastric tumor near EC junction in January 2005. Histological examination showed the tumor was moderately differentiated adenocarcinoma. As the tumor was diagnosed as mucosal cancer, endoscopic mucosal dissection was performed. But pathological findings showed the depth of cancer cell invasion into deep submucosal layer. Then total resection of remnant stomach was performed. Both tumors were diagnosed as EBV-associated carcinoma. It is speculated that the mucosa changing after initial operation would give risk to a new occurrence of EBV-associated remnant gastric carcinoma. And then follow up after operation is important. Although some cases of EBV-associated remnant gastric carcinoma is found for short period after the primary surgery, our case second primary cancer was found 7 year after primary surgery. Long term follow-up by Endoscopy seems to be important.
{"title":"Epstein-Barr Virus (EBV) 関連胃癌手術7年後に発生したEBV関連残胃癌の1例","authors":"Koichi Takahashi, Yoshihide Otani, Nobuji Ogawa, Akihiro Yasumoto, A. Takeda, Mitsuo Miyazawa, Nozomi Shinozuka, Isamu Koyama, S. Arai, Shinichi Ota, Shin-ichi Ban","doi":"10.11405/NISSHOSHI.104.1728","DOIUrl":"https://doi.org/10.11405/NISSHOSHI.104.1728","url":null,"abstract":"A 52-year-old man undergoing distal gastrectomy for gastric cancer in July 1998 was found to have a 0-IIa type gastric tumor near EC junction in January 2005. Histological examination showed the tumor was moderately differentiated adenocarcinoma. As the tumor was diagnosed as mucosal cancer, endoscopic mucosal dissection was performed. But pathological findings showed the depth of cancer cell invasion into deep submucosal layer. Then total resection of remnant stomach was performed. Both tumors were diagnosed as EBV-associated carcinoma. It is speculated that the mucosa changing after initial operation would give risk to a new occurrence of EBV-associated remnant gastric carcinoma. And then follow up after operation is important. Although some cases of EBV-associated remnant gastric carcinoma is found for short period after the primary surgery, our case second primary cancer was found 7 year after primary surgery. Long term follow-up by Endoscopy seems to be important.","PeriodicalId":341053,"journal":{"name":"The Japanese journal of gastro-enterology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128463079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A 74-year-old woman was admitted to our hospital to treat her hepatocellular carcinoma (stage IVB) with multiple lung metastases. She was treated with 3 times of hepatic arterial infusion of cisplatin powder (IA-call). After the treatment, liver mass and lung tumors were disappeared and high levels of tumor markers (AFP and PIVKA-II) were markedly decreased. These data revealed that a complete response (CR) was obtained for her. She has still been maintained in CR for 2 years since the first treatment.
{"title":"多発肺転移をともなう進行肝細胞癌に微粉末化シスプラチン(動注用アイエーコール®）肝動注が著効した1症例","authors":"武 飯田, 裕子 水永, 正 岡澤, 昌子 土屋, 善人 稲本, 聖治 戒能, 倫好 草野, 美雪 戒能, 典枝 黒川, 忠彦 伊藤","doi":"10.11405/NISSHOSHI.104.1738","DOIUrl":"https://doi.org/10.11405/NISSHOSHI.104.1738","url":null,"abstract":"A 74-year-old woman was admitted to our hospital to treat her hepatocellular carcinoma (stage IVB) with multiple lung metastases. She was treated with 3 times of hepatic arterial infusion of cisplatin powder (IA-call). After the treatment, liver mass and lung tumors were disappeared and high levels of tumor markers (AFP and PIVKA-II) were markedly decreased. These data revealed that a complete response (CR) was obtained for her. She has still been maintained in CR for 2 years since the first treatment.","PeriodicalId":341053,"journal":{"name":"The Japanese journal of gastro-enterology","volume":"7 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132153925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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