{"title":"Increased Seizure Risk Among the Patients During the COVID-19 Pandemic: Is a Single-Drug Regime Better?","authors":"Ümmü Serpil Sarı","doi":"10.14744/bmj.2022.99815","DOIUrl":"https://doi.org/10.14744/bmj.2022.99815","url":null,"abstract":"","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67322959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Determination of the Diet Quality and Emotional Appetite of Overweight and Obese Individuals Who Consult to the Nutrition and Diet Clinic During the Pandemic Period","authors":"Deran Dalbudak Sansar","doi":"10.14744/bmj.2023.92005","DOIUrl":"https://doi.org/10.14744/bmj.2023.92005","url":null,"abstract":"","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67323474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: This study aimed to compare the status of disability between chronic renal failure patients who underwent hemodialysis (HD) and patients with paraplegia due to spinal cord injuries. Methods: Thirty chronic renal failure patients (12 women and 18 men) who have been receiving regular HD treat-ment (HD group) and 30 paraplegic patients (Paraplegic group) (22 women and 8 men) defined by Spinal Cord Injury Association were recruited to the study. All sociodemographical characteristics and brief personal information about the dialysis and paraplegic patients were recorded. The disability status was analyzed by Craig Handicap Assessment and Reporting Technique Short Form (CHART-SF). Results: The mean ages of patients were 39.40±6.81 in HD and 36.17±8.92 years in the spinal cord injury group (p>0.05). According to CHART subgroup analysis, the physical independence level was 89.20±21.43 and 77.87±33.25 (p>0.05); cognitive evaluation was 91.97±18.15 and 77.63±33.25 (p<0.05*); mobility was 76.23±11.14 and 70.10±23.68 (p>0.05); roles and activities status were 24.58±35.10 and 38.75±40.22 (p>0.05); social integration was 70.37±16.30 and 64.37±22,64 (p>0.05); in HD and paraplegic group, respectively. Conclusion: Although there is no physically handicapped state in HD patients, the severity of disability level is considered to be as high as in paraplegic patients.
{"title":"Disability in Patients with Spinal Cord Injury and Chronic Renal Failure","authors":"Işıl Üstün","doi":"10.14744/bmj.2023.41275","DOIUrl":"https://doi.org/10.14744/bmj.2023.41275","url":null,"abstract":"Objectives: This study aimed to compare the status of disability between chronic renal failure patients who underwent hemodialysis (HD) and patients with paraplegia due to spinal cord injuries. Methods: Thirty chronic renal failure patients (12 women and 18 men) who have been receiving regular HD treat-ment (HD group) and 30 paraplegic patients (Paraplegic group) (22 women and 8 men) defined by Spinal Cord Injury Association were recruited to the study. All sociodemographical characteristics and brief personal information about the dialysis and paraplegic patients were recorded. The disability status was analyzed by Craig Handicap Assessment and Reporting Technique Short Form (CHART-SF). Results: The mean ages of patients were 39.40±6.81 in HD and 36.17±8.92 years in the spinal cord injury group (p>0.05). According to CHART subgroup analysis, the physical independence level was 89.20±21.43 and 77.87±33.25 (p>0.05); cognitive evaluation was 91.97±18.15 and 77.63±33.25 (p<0.05*); mobility was 76.23±11.14 and 70.10±23.68 (p>0.05); roles and activities status were 24.58±35.10 and 38.75±40.22 (p>0.05); social integration was 70.37±16.30 and 64.37±22,64 (p>0.05); in HD and paraplegic group, respectively. Conclusion: Although there is no physically handicapped state in HD patients, the severity of disability level is considered to be as high as in paraplegic patients.","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135841169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: The present study is intended to evaluate serum lipid levels in patients with spinal cord injury (SCI) and to investigate the factors affecting lipid levels. Methods: A total of 96 patients with SCI who were followed up in our Physical Medicine and Rehabilitation Clinic between 2018 and 2023 were included in this retrospective study. The American Spinal Injury Association Impairment Scale, Functional Ambulation Categories (FAC), SCI Spasticity Evaluation Tool and Spinal Cord Independence Measure, version III (SCIM III) assessments of the included patients were obtained from patient files and recorded. Serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL-c), high-density lipoprotein cholesterol (HDL-c), triglyceride (TG) levels, and TC/HDL-c ratios were evaluated. Results: Among the patients included, 41.7% had TC over 200 mg/dL, 32.3% had LDL-c over 130 mg/dL, 47.9% had HDL-c below 40 mg/dL, and 41.7% had a TC level above 150 mg/dL. In 29.2% of patients, the TC/HDL ratio was 4.5 or higher. 74 patients (77.1%) had an abnormality in at least one lipid profile. Male patients with SCI had lower HDL-c levels and higher TG levels and TC/HDL-c ratios than female SCI patients (p<0.05). There was a statistically significant correlation between TC and LDL-c and Body mass index (BMI) and FAC (p<0.05). HDL-c was significantly correlated with the duration of SCI, FAC, and SCIM III total score (p<0.05). There was a significant correlation be-tween TG levels and BMI only (p<0.05). There was a statistically significant positive correlation between TC/HDL-c ratio and BMI and a negative correlation between the duration of SCI and SCIM III total score (p<0.05). Conclusion: Dyslipidemia was present in the majority of patients with SCI. Dyslipidemia rates were higher in the group of male patients. There was a correlation between lipid levels and BMI, SCI duration, independence levels, and ambulation degrees.
{"title":"Evaluation of Serum Lipid Levels in Patients with Chronic Spinal Cord Injury","authors":"Arzu Atıcı","doi":"10.14744/bmj.2023.92300","DOIUrl":"https://doi.org/10.14744/bmj.2023.92300","url":null,"abstract":"Objectives: The present study is intended to evaluate serum lipid levels in patients with spinal cord injury (SCI) and to investigate the factors affecting lipid levels. Methods: A total of 96 patients with SCI who were followed up in our Physical Medicine and Rehabilitation Clinic between 2018 and 2023 were included in this retrospective study. The American Spinal Injury Association Impairment Scale, Functional Ambulation Categories (FAC), SCI Spasticity Evaluation Tool and Spinal Cord Independence Measure, version III (SCIM III) assessments of the included patients were obtained from patient files and recorded. Serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL-c), high-density lipoprotein cholesterol (HDL-c), triglyceride (TG) levels, and TC/HDL-c ratios were evaluated. Results: Among the patients included, 41.7% had TC over 200 mg/dL, 32.3% had LDL-c over 130 mg/dL, 47.9% had HDL-c below 40 mg/dL, and 41.7% had a TC level above 150 mg/dL. In 29.2% of patients, the TC/HDL ratio was 4.5 or higher. 74 patients (77.1%) had an abnormality in at least one lipid profile. Male patients with SCI had lower HDL-c levels and higher TG levels and TC/HDL-c ratios than female SCI patients (p<0.05). There was a statistically significant correlation between TC and LDL-c and Body mass index (BMI) and FAC (p<0.05). HDL-c was significantly correlated with the duration of SCI, FAC, and SCIM III total score (p<0.05). There was a significant correlation be-tween TG levels and BMI only (p<0.05). There was a statistically significant positive correlation between TC/HDL-c ratio and BMI and a negative correlation between the duration of SCI and SCIM III total score (p<0.05). Conclusion: Dyslipidemia was present in the majority of patients with SCI. Dyslipidemia rates were higher in the group of male patients. There was a correlation between lipid levels and BMI, SCI duration, independence levels, and ambulation degrees.","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135314221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: The number of patients diagnosed with ductal carcinoma in situ (DCIS) has increased in the past 20 years with the widespread use of mammography screening. This study aims to investigate which patients with DCIS should undergo sentinel lymph node biopsy (SLNB). Methods: Between 2008 and 2023, patients diagnosed with DCIS in the General Surgery Clinic were evaluated retrospectively. Age, clinical features, tumor nuclear grade, presence of comedonecrosis, tumor diameter, hormone receptor, presence of microinvasive components, axillary pathology, surgical interventions, locoregional recür-rences, overall and disease-free survival information of the patients were evaluated. Results: Forty-eight patients with a mean age of 52.2+12.4 years (25–76) were included in the study. Mastectomy was performed in 16, breast-conserving surgery in 32, SLNB in 21, axillary dissection in three, and no axillary-di-rected intervention was performed in 24 patients. Pure DCIS was detected in 44 patients and microinvasive component was detected in four patients (8.3%). No metastasis was detected after axillary sampling. It was statistically significant that a higher proportion of patients who underwent axillary intervention were in the mastectomy group and had diffuse microcalcifications in their mammograms (p<0.001 and p=0.009). Patients were followed up for a mean of 82.5 months, and locoregional recurrence was detected in 3 (6.25%) patients. One of the recurrences was due to DCIS, and the others were due to invasive cancer. The tumor sizes in these cases were above the average tumor size in the study. Conclusion: Although the absence of axillary metastasis in our study is attributed to the low number of patients and small mean tumor size, routine SLNB might not be performed in patients with DCIS due to the low rate of axillary metastasis. SLNB may be preferred only in cases where mastectomy will be performed.
{"title":"Is Sentinel Lymph Node Biopsy Necessary in Patients with Ductal Carcinoma in situ of the Breast?","authors":"Hakan Baysal","doi":"10.14744/bmj.2023.88700","DOIUrl":"https://doi.org/10.14744/bmj.2023.88700","url":null,"abstract":"Objectives: The number of patients diagnosed with ductal carcinoma in situ (DCIS) has increased in the past 20 years with the widespread use of mammography screening. This study aims to investigate which patients with DCIS should undergo sentinel lymph node biopsy (SLNB). Methods: Between 2008 and 2023, patients diagnosed with DCIS in the General Surgery Clinic were evaluated retrospectively. Age, clinical features, tumor nuclear grade, presence of comedonecrosis, tumor diameter, hormone receptor, presence of microinvasive components, axillary pathology, surgical interventions, locoregional recür-rences, overall and disease-free survival information of the patients were evaluated. Results: Forty-eight patients with a mean age of 52.2+12.4 years (25–76) were included in the study. Mastectomy was performed in 16, breast-conserving surgery in 32, SLNB in 21, axillary dissection in three, and no axillary-di-rected intervention was performed in 24 patients. Pure DCIS was detected in 44 patients and microinvasive component was detected in four patients (8.3%). No metastasis was detected after axillary sampling. It was statistically significant that a higher proportion of patients who underwent axillary intervention were in the mastectomy group and had diffuse microcalcifications in their mammograms (p<0.001 and p=0.009). Patients were followed up for a mean of 82.5 months, and locoregional recurrence was detected in 3 (6.25%) patients. One of the recurrences was due to DCIS, and the others were due to invasive cancer. The tumor sizes in these cases were above the average tumor size in the study. Conclusion: Although the absence of axillary metastasis in our study is attributed to the low number of patients and small mean tumor size, routine SLNB might not be performed in patients with DCIS due to the low rate of axillary metastasis. SLNB may be preferred only in cases where mastectomy will be performed.","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135314410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vitreoretinal surgery procedures and results in a tertiary eye hospital during the Covid-19 pandemic and national quarantine period","authors":"S. Ozcaliskan","doi":"10.14744/bmj.2022.00821","DOIUrl":"https://doi.org/10.14744/bmj.2022.00821","url":null,"abstract":"","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"233 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67321033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Depression and Sleep Quality in Restless Legs Syndrome/Willis-Ekbom Disease","authors":"C. Sayman","doi":"10.14744/bmj.2022.04909","DOIUrl":"https://doi.org/10.14744/bmj.2022.04909","url":null,"abstract":"","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67321112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: The COVID-19 pandemic caused a serious reduction both in blood donation and use of blood. The number of volunteer blood donors reduced to a great extent. Planning of blood transfusion services during a pandemic is essential to ensure appropriate management of blood reserve. The objective of this study was to define the transfusion needs of COVID-19 patients who needed to be hospitalized and to evaluate the impact on total hospital blood supply. Methods: This is a single-center retrospective observational study evaluating blood transfusion requirements over a 1-year period between March 11, 2020 and March 1, 2021 at the transfusion center. The clinical data were obtained from the hospital information management system records, and transfusion data were obtained from the laboratory information management system. Results: One hundred and eighty-one (44.5%) of 406 COVID-19 patients who were hospitalized needed blood transfusion. A total of 4106 (17.6%) units of blood were transfused to these individuals. The majority of blood products used were fresh frozen plasma (FFP). The number of transfusion of platelets (PLT) and erythrocyte suspensions (ES) were lower. The ES, PLT, and FFP transfusion rates in COVID-19 patients were found lower compared to patients who did not have COVID-19. The total number of transfusions of blood components was found significantly reduced compared to the same period in previous years. There was a 10.4% decrease in total blood component count, 15.4% decrease in ES, 40.2% decrease in PLT, and an 11% increase in FFP. Conclusion: While pandemics may reduce blood supply, our study showed that the rate of use of blood products was low in COVID-19 patients who were hospitalized. Studies examining patient factors may help to elucidate the mechanisms that affect the use of blood products in hospitalized COVID-19 populations to a greater extent.
{"title":"Do You Need More Blood Product or No! Use of Blood and Blood Products During COVID-19 Pandemic","authors":"Selma Dağcı","doi":"10.14744/bmj.2023.14632","DOIUrl":"https://doi.org/10.14744/bmj.2023.14632","url":null,"abstract":"Objectives: The COVID-19 pandemic caused a serious reduction both in blood donation and use of blood. The number of volunteer blood donors reduced to a great extent. Planning of blood transfusion services during a pandemic is essential to ensure appropriate management of blood reserve. The objective of this study was to define the transfusion needs of COVID-19 patients who needed to be hospitalized and to evaluate the impact on total hospital blood supply. Methods: This is a single-center retrospective observational study evaluating blood transfusion requirements over a 1-year period between March 11, 2020 and March 1, 2021 at the transfusion center. The clinical data were obtained from the hospital information management system records, and transfusion data were obtained from the laboratory information management system. Results: One hundred and eighty-one (44.5%) of 406 COVID-19 patients who were hospitalized needed blood transfusion. A total of 4106 (17.6%) units of blood were transfused to these individuals. The majority of blood products used were fresh frozen plasma (FFP). The number of transfusion of platelets (PLT) and erythrocyte suspensions (ES) were lower. The ES, PLT, and FFP transfusion rates in COVID-19 patients were found lower compared to patients who did not have COVID-19. The total number of transfusions of blood components was found significantly reduced compared to the same period in previous years. There was a 10.4% decrease in total blood component count, 15.4% decrease in ES, 40.2% decrease in PLT, and an 11% increase in FFP. Conclusion: While pandemics may reduce blood supply, our study showed that the rate of use of blood products was low in COVID-19 patients who were hospitalized. Studies examining patient factors may help to elucidate the mechanisms that affect the use of blood products in hospitalized COVID-19 populations to a greater extent.","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135310813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: Huntington’s disease (HD), characterized by choreiform movements, psychiatric problems, and dementia, is an inherited progressive neurodegenerative disorder. While HD is typically perceived as a motor disorder, cognitive decline could manifest before the clinical symptoms. Cognitive impairments might appear as emotional instability, decreased vocabulary, or impaired executive functions. Herein, we aimed to evaluate the cognitive findings of our patients diagnosed with HD and the relationship with disease parameters. Methods: Our study included 15 patients and fifteen controls. To determine the clinical findings of the patients, the unified HD rating scale (UHDRS) was administered, and total motor score (TMS), independence scale scores, and functional capacity scores were calculated. To assess the cognitive status of individuals, the Montreal Cognitive Assessment Battery Turkish validated form (MOCA-TR), Stroop test Turkish validated form (Stroop test TBAG form), and Symbol Digit Modalities Test were conducted. Results: The MoCA-TR scores were significantly reduced in HD patients compared to controls (p<0.001). Among all patients, there was a notable elongation in completion time for the Stroop test TBAG form than controls (p<0.05). The MoCA-TR showed a robust negative correlation with the TMS while exhibiting a marked positive correlation with the independence scale score and functional capacity. Conversely, the MoCA-TR demonstrated a moderate negative correlation with the disease burden score (DBS) and a pronounced negative relationship with the progression rate (p<0.05). A strong opposing correlation was observed between cytosine-adenine-guanine (CAG) repeats and the age of disease onset, whereas a highly significant positive relationship emerged between CAG repeats and the DBS (p<0.05). Conclusion: We have demonstrated a strong correlation between patients’ cognitive scores and disease clinical findings. Patients’ cognitive scores have also been shown to impact disease burden and disease progression rate. The designation of cognitive impairment in the early stages could contribute to personalized disease-modifying treatment strategies
{"title":"Evaluation of Cognitive Disorders in Huntington’s Disease and Their Relationship with Motor Symptoms and Trinucleotide Repeat Expansion","authors":"Esma Kobak Tur","doi":"10.14744/bmj.2023.49389","DOIUrl":"https://doi.org/10.14744/bmj.2023.49389","url":null,"abstract":"Objectives: Huntington’s disease (HD), characterized by choreiform movements, psychiatric problems, and dementia, is an inherited progressive neurodegenerative disorder. While HD is typically perceived as a motor disorder, cognitive decline could manifest before the clinical symptoms. Cognitive impairments might appear as emotional instability, decreased vocabulary, or impaired executive functions. Herein, we aimed to evaluate the cognitive findings of our patients diagnosed with HD and the relationship with disease parameters. Methods: Our study included 15 patients and fifteen controls. To determine the clinical findings of the patients, the unified HD rating scale (UHDRS) was administered, and total motor score (TMS), independence scale scores, and functional capacity scores were calculated. To assess the cognitive status of individuals, the Montreal Cognitive Assessment Battery Turkish validated form (MOCA-TR), Stroop test Turkish validated form (Stroop test TBAG form), and Symbol Digit Modalities Test were conducted. Results: The MoCA-TR scores were significantly reduced in HD patients compared to controls (p<0.001). Among all patients, there was a notable elongation in completion time for the Stroop test TBAG form than controls (p<0.05). The MoCA-TR showed a robust negative correlation with the TMS while exhibiting a marked positive correlation with the independence scale score and functional capacity. Conversely, the MoCA-TR demonstrated a moderate negative correlation with the disease burden score (DBS) and a pronounced negative relationship with the progression rate (p<0.05). A strong opposing correlation was observed between cytosine-adenine-guanine (CAG) repeats and the age of disease onset, whereas a highly significant positive relationship emerged between CAG repeats and the DBS (p<0.05). Conclusion: We have demonstrated a strong correlation between patients’ cognitive scores and disease clinical findings. Patients’ cognitive scores have also been shown to impact disease burden and disease progression rate. The designation of cognitive impairment in the early stages could contribute to personalized disease-modifying treatment strategies","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"124 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135317808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}