Objectives: Inflammatory bowel disease (IBD) is a chronic disease, in which autoimmunity has been thought to involve the mucosal barrier, leading to a chronic inflammation and affecting different regions and layers of the gastrointestinal tract. The main types of IBD include ulcerative colitis (UC), Crohn’s disease (CD), and indeterminate colitis which often cannot be distinguished from the other ones. The prevalence of reduced bone mineral density (BMD) is higher in patients with IBD than healthy individuals. In this study, we aimed to evaluate the BMD in patients with UC, CD, and in healthy individuals. Methods: A total of 71 IBD patients (21 CD, 50 UC) and 30 age-and sex-matched healthy individuals were included in this prospective study. Dual-energy X-ray absorptiometry was performed to measure BMD of the vertebra and femoral neck. Results: There was no significant difference in the age, sex, and body mass index between the study and control groups (p<0.05). The BMD values were significantly lower in 16 of 21 CD patients (76.2%). A total of 27 patients (54%) with UC had pathological T-scores, indicating borderline significance (p=0.058). The reduction in BMD was not significant between the IBD patients treated with >5 g/day corticosteroids and those treated with ≤5 g/day or treatment-naive patients (p>0.05). Conclusion: Our study results suggest that BMD is significantly lower in IBD patients, particularly in CD patients.
{"title":"Factors Affecting Bone Mineral Density in Inflammatory Bowel Disease","authors":"M. Köroğlu","doi":"10.14744/bmj.2021.09709","DOIUrl":"https://doi.org/10.14744/bmj.2021.09709","url":null,"abstract":"Objectives: Inflammatory bowel disease (IBD) is a chronic disease, in which autoimmunity has been thought to involve the mucosal barrier, leading to a chronic inflammation and affecting different regions and layers of the gastrointestinal tract. The main types of IBD include ulcerative colitis (UC), Crohn’s disease (CD), and indeterminate colitis which often cannot be distinguished from the other ones. The prevalence of reduced bone mineral density (BMD) is higher in patients with IBD than healthy individuals. In this study, we aimed to evaluate the BMD in patients with UC, CD, and in healthy individuals. Methods: A total of 71 IBD patients (21 CD, 50 UC) and 30 age-and sex-matched healthy individuals were included in this prospective study. Dual-energy X-ray absorptiometry was performed to measure BMD of the vertebra and femoral neck. Results: There was no significant difference in the age, sex, and body mass index between the study and control groups (p<0.05). The BMD values were significantly lower in 16 of 21 CD patients (76.2%). A total of 27 patients (54%) with UC had pathological T-scores, indicating borderline significance (p=0.058). The reduction in BMD was not significant between the IBD patients treated with >5 g/day corticosteroids and those treated with ≤5 g/day or treatment-naive patients (p>0.05). Conclusion: Our study results suggest that BMD is significantly lower in IBD patients, particularly in CD patients.","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67320793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interventional Procedures Under the Guidance of Mammography in Breast Diseases","authors":"Fatma Nur Soylu Boy","doi":"10.14744/bmj.2022.50570","DOIUrl":"https://doi.org/10.14744/bmj.2022.50570","url":null,"abstract":"","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67321529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MR Imaging Evaluation of the Volume Changes and the Signs of Deformation in the Breasts with Granulomatous Mastitis","authors":"Fatma Nur Soylu Boy","doi":"10.14744/bmj.2022.09327","DOIUrl":"https://doi.org/10.14744/bmj.2022.09327","url":null,"abstract":"","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67321255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Has IV TPA application decreased in our Stroke Center during the pandemic period?","authors":"Isil Kalyoncu Aslan","doi":"10.14744/bmj.2022.63325","DOIUrl":"https://doi.org/10.14744/bmj.2022.63325","url":null,"abstract":"","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67322284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Plasma vitamin D levels in patients with vitiligo","authors":"N. Akpolat","doi":"10.14744/bmj.2022.96158","DOIUrl":"https://doi.org/10.14744/bmj.2022.96158","url":null,"abstract":"","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67323295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is There Any Relation with Chronic Headache Disorder and Dementia?","authors":"M. Ülker","doi":"10.14744/bmj.2022.13471","DOIUrl":"https://doi.org/10.14744/bmj.2022.13471","url":null,"abstract":"","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67321308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The clinical and radiological outcomes of surgical decompression in older patients with lumbar spinal stenosis","authors":"Ş. Gök","doi":"10.14744/bmj.2022.51423","DOIUrl":"https://doi.org/10.14744/bmj.2022.51423","url":null,"abstract":"","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67321740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Unrecognized Symptom Of Brain Tumors In The Emergency Department: Left Homonymous Hemianopsia","authors":"M. Ekşioğlu","doi":"10.14744/bmj.2022.68442","DOIUrl":"https://doi.org/10.14744/bmj.2022.68442","url":null,"abstract":"","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67321963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The relationship of CRP/Albumin ratio with etiology and prognosis in acute ischaemic stroke","authors":"M. Ülker","doi":"10.14744/bmj.2022.60352","DOIUrl":"https://doi.org/10.14744/bmj.2022.60352","url":null,"abstract":"","PeriodicalId":34126,"journal":{"name":"Bogazici Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67322236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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