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Physiology, Genomics, and Biotechnological Applications of Extremophiles最新文献

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Extremophiles and Their Application in Bioremediation 极端微生物及其在生物修复中的应用
Pub Date : 1900-01-01 DOI: 10.4018/978-1-7998-9144-4.ch009
H. Pandey, Devendra N. Singh, Vinay Kumar Dhiman, V. K. Dhiman, D. Pandey
A microorganism dwelling in severe environmental conditions is termed an extremophile. These unfavorable environmental conditions include high salinity, toxin compounds, heavy metals, unfavorable temperature, and extremely acidic and alkaline pH. Microorganisms belonging to prokaryotes include true bacteria and archaea bacteria which prevail in harsh environments. In recent years, extremophilic, basically, archaea bacteria have been reported for their immense potential application in the bioremediation process. Bioremediation is a technique that utilizes microorganisms for the decomposition of organic and inorganic pollutants; anthropogenic activities are the basic cause of soil pollution, water pollution, and air pollution globally. Extremophiles are capable of producing enzymes that are thermolabile and can function normally even in extreme conditions. These enzymes and proteins can be utilized in the bioremediation process under extreme pH, heavy metal stress, and unfavorable temperature conditions. In this chapter, the role of extremophiles in bioremediation is discussed.
生活在恶劣环境条件下的微生物称为嗜极微生物。这些不利的环境条件包括高盐度、毒素化合物、重金属、不利的温度、极酸和极碱性。原核生物的微生物包括真细菌和古细菌,它们在恶劣的环境中占优势。近年来,极端微生物,基本上是古细菌,因其在生物修复过程中的巨大潜力而被报道。生物修复是一种利用微生物分解有机和无机污染物的技术;人类活动是全球土壤污染、水污染和大气污染的根本原因。极端微生物能够产生耐热酶,即使在极端条件下也能正常工作。这些酶和蛋白质可用于极端pH、重金属胁迫和不利温度条件下的生物修复过程。在本章中,讨论了极端微生物在生物修复中的作用。
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引用次数: 0
Extremophiles 极端微生物
Pub Date : 1900-01-01 DOI: 10.4018/978-1-7998-9144-4.ch001
Aniruddh Rabari, Janki Ruparelia, C. Jha
Extremophiles are extreme nature devotees, mostly bacteria and archaea, which bloom with extreme environmental parameters like temperature, pH, pressure, and salinity. Extremophiles are responsible for the beginning of geographical structures throughout the evolution and establishment of all presently known ecological units. They are classified into several categories like acidophiles, alkaliphiles, psychrophiles, thermophiles, xerophiles, piezophiles/barophiles, halophiles, and many more, as given in this chapter. The subsistence of these microorganisms in extreme environments produces extremolytes and extremozymes that have the potential of valued resources for the enlargement of a bio-based economy. In addition to their solicitations, extremophiles offer treasured information regarding the physiochemical limitations of natural life. This chapter mainly evaluates extremophiles, the classification of extremophiles, and their biotechnological applications in grey, white, and red biotechnologies with the perspective of exploring celestial life.
极端微生物是极端的自然爱好者,主要是细菌和古菌,它们在极端的环境参数下繁殖,如温度、pH值、压力和盐度。在所有已知的生态单位的进化和建立过程中,极端微生物负责地理结构的开始。它们被分为几类,如嗜酸菌、嗜碱菌、嗜冷菌、嗜热菌、嗜干菌、嗜水菌/嗜氧菌、嗜盐菌等等,如本章所述。这些微生物在极端环境下的生存产生了极溶物和极酶,这些极溶物和极酶具有扩大生物经济的宝贵资源潜力。除了它们的恳求之外,极端微生物还提供了关于自然生命的物理化学限制的宝贵信息。本章主要从探索天体生命的角度对极端微生物、极端微生物的分类及其在灰色、白色和红色生物技术方面的生物技术应用进行评价。
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引用次数: 0
Psychrophiles 它们有着
Pub Date : 1900-01-01 DOI: 10.4018/978-1-7998-9144-4.ch005
S. Bhatt
Life on the Earth has evolved in the cold environments. Such cold habitats pose special challenges to the microbes in cold ecosystems, such as minimum metabolic activities, very limited nutrient availability, and often extreme conditions such as pH and salinity apart from temperature. Microbial communities surviving under these extreme conditions must have evolved complex structural and functional adaptations. Prokaryotic adaptations to cold environments are through physiological adaptations by increasing membrane fluidity through large amount of unsaturated fatty acids. These microbes also possess some cold adapted proteins whose steady state levels are maintained. They also produce certain compounds such as polyamines, sugars, polyols, amino acids, and some antifreeze proteins to protect themselves under freezing conditions. They also produce exopolymeric substances that promote adhesion of microbes to moist surfaces to induce biofilm formation which helps getting nutrients and protect the cells from harsh conditions. Antioxidants help destroying toxic reactive oxygen species.
地球上的生命是在寒冷的环境中进化的。这种寒冷的栖息地对寒冷生态系统中的微生物构成了特殊的挑战,例如最低的代谢活动,非常有限的营养物质可用性,以及除了温度之外的pH和盐度等极端条件。在这些极端条件下生存的微生物群落必须进化出复杂的结构和功能适应。原核生物对寒冷环境的适应是通过大量不饱和脂肪酸增加膜流动性的生理适应。这些微生物还具有一些冷适应蛋白,其稳定状态水平得以维持。它们还会产生某些化合物,如多胺、糖、多元醇、氨基酸和一些防冻蛋白,以在冷冻条件下保护自己。它们还产生外聚合物质,促进微生物与潮湿表面的粘附,从而诱导生物膜的形成,从而帮助获取营养并保护细胞免受恶劣条件的影响。抗氧化剂有助于破坏有毒的活性氧。
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引用次数: 44
Thermophilic Bacterial Exopolysaccharides 嗜热细菌胞外多糖
Pub Date : 1900-01-01 DOI: 10.4018/978-1-7998-9144-4.ch016
R. Goswami, Bidyut Bandyopadhyay, S. Sadhukhan
Bacterial exopolysaccharides have enormous diversity with valuable characteristics, synthesized by various pathways in extreme conditions like salinity, geothermal springs, or hydrothermal vents. Due to extreme environments, these microorganisms have various adaption principles (e.g., low pH, high temperature, high saltation, and high radiation). Exopolysaccharide is an organic compound produced by most bacteria during fermentation using various carbon sources, resulting in a jelly-like or mass network structure outside the cell wall. This biopolymer has an adherent cohesive layer throughout the cell layer. Hot spring bacterial polysaccharides contain diverse extracellular polymeric substances. With a gain in popularity in applications of thermophilic microbial polysaccharides and its demand in diverse value-added industrial products, this chapter aims to provide valuable information on the physicochemical function and biotechnological applications in the field of food, medical imaging, nano-drugs, bioremediation, cancer, anti-bacterial, tissue engineering, etc.
细菌胞外多糖具有巨大的多样性和有价值的特性,在盐度、地热泉或热液喷口等极端条件下通过各种途径合成。由于极端的环境,这些微生物有不同的适应原则(如低pH值、高温、高跃变、高辐射)。胞外多糖是大多数细菌在发酵过程中利用各种碳源产生的一种有机化合物,在细胞壁外形成果冻状或块状网络结构。该生物聚合物具有贯穿细胞层的粘附内聚层。温泉细菌多糖含有多种胞外聚合物质。随着嗜热微生物多糖的广泛应用及其在各种高附加值工业产品中的需求,本章旨在提供有关其在食品、医学成像、纳米药物、生物修复、癌症、抗菌、组织工程等领域的理化功能和生物技术应用的宝贵信息。
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引用次数: 0
Halophiles 嗜盐菌
Pub Date : 1900-01-01 DOI: 10.4018/978-1-7998-9144-4.ch002
A. Gunjal, Nilaja Badodekar
Halophiles are extremophilic salt-loving microorganisms that can survive in an extremely high level of salinity (10-30% NaCl). They belong to all three groups (i.e., bacteria, archaea, and eukaryotes). Halophiles tolerate high salt concentration due to unique cellular adaptations like salt-in strategy, compatible solute strategy, and enzyme adaptations. The chapter describes the classification, physiology, ecology, and mechanisms of adaptations and biotechnological applications of halophiles.
嗜盐菌是嗜极嗜盐微生物,可以在极高的盐度(10-30% NaCl)下生存。它们属于所有三组(即细菌、古细菌和真核生物)。由于独特的细胞适应,如盐入策略,相容溶质策略和酶适应,嗜盐菌耐受高浓度盐。本章描述了嗜盐菌的分类、生理、生态、适应机制和生物技术应用。
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引用次数: 66
Extremophiles as a Source of Biotechnological Products 极端微生物作为生物技术产品的来源
Pub Date : 1900-01-01 DOI: 10.4018/978-1-7998-9144-4.ch015
P. Murthy, V. M, S. H. P., Inderjit Prakash
Extremophile and extremozyme capabilities to uphold catalytic actions under extreme situations open up a varied array of biotechnological applications. Extremophiles are a rich supply of biocatalysts used for innumerable purposes. Bioactive molecules and enzymes isolated from organisms inhabiting risky environments being used in biological innovation pipelines and pharmaceutical have positive claims. The species biodiversity has favourable reservoir of the unexploited amalgams with biotechnological significance. Prospective solicitations of extremozymes, chiefly as catalysis of multistep progressions, quorum sensing, bioremediation, biofuel, biodiversity and prospecting, biomining, and genetic technology are explored. To boost the biotechnological uses of extremozymes, research and development efforts are needed to address hurdles such as extremophile culture, gene expression in host cells, and extremozyme bioprocessing. Extremophiles can be a resource for innovative biotechnological comprising industrial biotechnology, agriculture, medical, food, and environmental biotechnology.
极端微生物和极端酶在极端情况下维持催化作用的能力开辟了各种各样的生物技术应用。极端微生物是一种丰富的生物催化剂,用于无数的目的。从生活在危险环境中的生物体中分离出来的生物活性分子和酶被用于生物创新管道和制药领域。物种多样性具有良好的未开发汞合金资源库,具有生物技术意义。极酶的潜在用途,主要是作为多步骤进展的催化剂,群体感应,生物修复,生物燃料,生物多样性和勘探,生物采矿和基因技术进行了探索。为了促进极端酶的生物技术应用,研究和开发工作需要解决诸如极端微生物培养、宿主细胞中的基因表达和极端酶生物处理等障碍。极端微生物可以成为创新生物技术的资源,包括工业生物技术、农业、医疗、食品和环境生物技术。
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引用次数: 1
期刊
Physiology, Genomics, and Biotechnological Applications of Extremophiles
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