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ICU Readmission in Cardiac Surgical Subset: A Problem Worth Pondering 心脏外科患者ICU再入院:一个值得思考的问题
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1759816
Jaffrey Kalaiselvan, R. Kashav, Jasvinder K Kohli, R. Magoon, Iti Shri, V. Grover, Narender Singh Jhajharia
Abstract Over the past decades, there have been noteworthy advancements in the cardiac surgical practice that have assisted fast-tracking and enhanced recovery after cardiac surgery (ERACS). With that said, intensive care unit (ICU) readmission in this high-risk patient cohort entails a significant morbidity–mortality burden. As an extension of the same, there has been a heightened emphasis on a comprehensive evaluation of the predisposition to readmission following a primary ICU discharge. However, the variability of the institutional perioperative practices and the research complexities compound our understanding of this heterogeneous outcome of readmission, which is intricately linked to both patient and organizational factors. Moreover, a discussion on ICU readmission in the recent times can only be rendered comprehensive when staged in close conjunction to the fast-tracking practices in cardiac surgery. From a more positive probing of the matter, a preventative outlook can likely mitigate a part of the larger problem of ICU readmission. Herein, focused cardiac prehabilitation programs can play a potential role given the emerging literature on the positive impact of the former on the most relevant readmission causes. Therefore, the index review article aims to address the subject of cardiac surgical ICU readmission, highlighting the magnitude and burden, the causes and risk-factors, and the research complexities alongside deliberating the topic in the present-day context of ERACS and cardiac prehabilitation.
在过去的几十年里,心脏外科实践有了显著的进步,有助于心脏手术后快速追踪和增强恢复(ERACS)。综上所述,在这一高危患者队列中,再入住重症监护病房(ICU)会带来显著的发病率-死亡率负担。作为同样的延伸,对初级ICU出院后再入院倾向的综合评估得到了高度重视。然而,机构围手术期实践的可变性和研究的复杂性使我们对再入院的异质性结果的理解复杂化,这与患者和组织因素错综复杂地联系在一起。此外,最近关于ICU再入院的讨论只有在与心脏外科快速跟踪实践紧密结合时才能呈现全面。从一个更积极的探索问题,预防性的前景可能会减轻ICU再入院的更大问题的一部分。在此,鉴于关于心脏康复对最相关的再入院原因的积极影响的新兴文献,重点心脏康复计划可以发挥潜在的作用。因此,该索引综述文章旨在解决心脏外科ICU再入院的问题,强调其规模和负担,原因和风险因素,以及研究的复杂性,同时在当前ERACS和心脏康复的背景下审议该主题。
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引用次数: 0
Echocardiography for Left Ventricular Assist Device Patients 左心室辅助装置患者的超声心动图
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1757363
P. Menon, P. Kapoor, Minati Choudhury
Heart transplantation is the only cure for patients with end-stage heart failure; the shortage of donors has led to a high mortality rate among these patients. A left ventricular assist device (LVAD) is a device to provide mechanical circulatory support for patients unresponsive to heart failure therapy. Echocardiography should be considered an indispensable tool in the evaluation of patients with an LVAD. In fact, as outlined in this review, it provides useful and readily available information that could be crucial for the patient's survival. In the preoperative assessment, it is important to detect through echocardiography conditions and parameters that could hint the development of a postoperative complication, in order to treat them before LVAD implant or to consider the patient ineligible to this advanced treatment.
心脏移植是治疗终末期心力衰竭的唯一方法;捐献者的短缺导致了这些病人的高死亡率。左心室辅助装置(LVAD)是一种为对心力衰竭治疗无反应的患者提供机械循环支持的装置。超声心动图应该被认为是一个不可或缺的工具,在评估患者与左室辅助功能。事实上,正如这篇综述所概述的,它提供了有用的和现成的信息,可能对患者的生存至关重要。在术前评估中,重要的是通过超声心动图检测可能提示术后并发症发展的情况和参数,以便在LVAD植入前进行治疗或考虑患者不适合这种高级治疗。
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引用次数: 0
Technical Details of Rechanneling of Obstructive Coronary Sinus Type of Totally Anomalous Pulmonary Venous Connection Using Malm's Coronary Sinus Cutback Technique and Left Atrial Augmentation: A Video Presentation 利用马尔姆冠状窦切断技术和左心房增强技术重新通道阻塞性冠状窦型完全异常肺静脉连接的技术细节:视频报告
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1759806
U. Chowdhury, Niwin George, S. B., Balaji Chandhirasekar, S. Goja, Nagasai Manjusha, N. Pandey, P. Kapoor
Abstract Obstructive coronary sinus totally anomalous pulmonary venous connection although rare, is associated with a high mortality. A 2-month-old female child diagnosed with obstructive coronary sinus type of totally anomalous pulmonary venous connection and severe pulmonary arterial hypertension underwent complete unroofing of the coronary sinus by the “coronary sinus cutback technique” of Malm with left atrial augmentation and atrial septal fenestration.
梗阻性冠状窦完全异常肺静脉连接虽然罕见,但死亡率高。一个2个月大的女婴被诊断为阻塞性冠状窦型肺静脉连接完全异常和严重肺动脉高压,采用马尔姆“冠状窦切断技术”左房增强和房间隔开窗完全打开冠状窦。
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引用次数: 0
Sepsis Associated with Extracorporeal Membrane Oxygenation 脓毒症与体外膜氧合有关
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1757392
Aashish Jain, Y. Mehta
Sepsis in patients on extracorporeal membrane oxygenation (ECMO) remains a serious complication. Its presence is a poor prognostic marker and increases overall mortality. Adult patients with prolonged duration on ECMO are at high risk of developing sepsis. Ventilator-associated pneumonia and bloodstream infections are the main sources of infection these patients. A strong early suspicion, drawing adequate volume for blood cultures, and early and timely administration of empirical antibiotics can help control the infection and decrease the morbidity and mortality. The diagnostic and the treatment are both challenging. Cardiac patients have increased risk of nosocomial infection while on ECMO, which may be in part due to longer cannulation times, as well as increased likelihood of undergoing major procedures or having an open chest.
体外膜氧合(ECMO)患者的脓毒症仍然是一个严重的并发症。它的存在是一个预后不良的标志,并增加总体死亡率。ECMO持续时间延长的成年患者发生败血症的风险很高。呼吸机相关性肺炎和血流感染是这些患者的主要感染源。强烈的早期怀疑,抽取足够的血培养量,以及早期和及时给予经验性抗生素可以帮助控制感染并降低发病率和死亡率。诊断和治疗都具有挑战性。心脏患者在ECMO期间发生医院感染的风险增加,部分原因可能是插管时间较长,以及接受重大手术或开胸的可能性增加。
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引用次数: 0
The Importance of TEE Examination in Patients with Pseudoaneurysm of Arch of Aorta Post-TEVAR Procedure tevar术后假性主动脉弓动脉瘤TEE检查的重要性
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1756473
Tanya Mital, P. Kapoor
A 57-year-old male patient presented to the emergency department with acute onset severe and tearing pain in the back. He was a chronic smoker and was a known hypertensive. He was admitted in view of type B aortic dissection with entry tear distal to left subclavian artery (LSCA) and underwent thoracic endovascular aortic repair (TEVAR) procedure for the same. Two stents (34–30–200mm size, Ankura, Lifetech, Nanshan District, Shenzhen, China) were placed overlapping each other to cover the dissection flap starting from distal end of left common carotid artery to proximal part of celiac artery. Post-stenting, patient developed recurrent episodes of melena, abdominal distension, and fever that were managed conservatively. Two months later, a routine follow-up computed tomographic aortic angiography revealed a focal contrast filled outpouching (2.1*1.9cm) extending from the proximal part of endovascular stent with surrounding thrombosis from anterior wall of the aortic arch. On inspecting the arch vessels, an ostial occlusion of LSCA was also discovered. Routine blood investigations were all within normal limits. Two-dimensional echocardiography showed a normal biventricular function with concentric left ventricular hypertrophy. All valves were normal.
一名57岁男性患者因急性发作的背部严重撕裂性疼痛而就诊于急诊科。他长期吸烟,并有高血压。他因B型主动脉夹层并左侧锁骨下动脉(LSCA)远端进入撕裂而入院,并接受了胸椎血管内主动脉修复(TEVAR)手术。两个支架(34-30-200mm尺寸,Ankura, Lifetech,南山区,中国深圳)相互重叠放置,覆盖从左颈总动脉远端到腹腔动脉近端的夹层皮瓣。支架置入术后,患者出现黑黑、腹胀和发烧的反复发作,并予以保守治疗。2个月后,例行随访ct主动脉造影,发现血管内支架近端有局灶性造影剂填充的突起(2.1*1.9cm),主动脉弓前壁周围有血栓形成。在检查弓血管时,还发现了LSCA的口闭塞。血常规检查均在正常范围内。二维超声心动图显示双心室功能正常,左心室同心性肥厚。所有瓣膜正常。
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引用次数: 0
Heparin-Induced Fever in a Cardiac Transplant Candidate 肝素诱发的心脏移植患者发热
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1759811
Payal R. Patel, Bria Giacomino
Abstract Patient admitted to intensive care units frequently have fevers. A less common cause for fever is a drug-induced fever. For patients who are candidates for heart transplantation, persistent fevers can place a hold on their transplant candidacy until the etiology is found and the fevers resolve. We present a case of a patient with dilated cardiomyopathy who experienced fevers thought secondary to heparin that improved only with discontinuation of therapy and later underwent successful heart transplantation. Only three prior case reports of heparin-induced fevers are currently described in literature.
入住重症监护病房的病人经常发烧。一种不太常见的发烧原因是药物引起的发烧。对于准备进行心脏移植的患者,持续发热可能会影响他们的移植候选资格,直到找到病因并退烧。我们提出了一例扩张型心肌病患者,他经历了发烧,认为继发于肝素,只有在停止治疗后才有所改善,后来进行了成功的心脏移植。只有三个先前的病例报告肝素引起的发烧,目前在文献中描述。
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引用次数: 0
Extracorporeal Membrane Oxygenation for Lung Transplantation 肺移植的体外膜氧合
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1757364
P. Kapoor
Extracorporeal membrane oxygenation (ECMO) has a clearly defined role in preoperative and postoperative transplant management of both heart and lung transplant. It is used on the recipient as a bridge to transplant, until the organs are made available. It provides a good support during surgery as a partial cardiopulmonary bypass. Posttransplant, it again provides support in case of an acute rejection or when graft dysfunction occurs, postoperatively. When ECMO as an indication is continued to provide support. Thus, ECMO has a positive impact on lung transplant outcomes.1 In a randomized control study, known as the CAESAR TRIAL in 2009, ECMO was confirmed as a definitive modern of treatment for ARDS.2 It gained the popularity for treating adult ARDS. Veith et al in 19773 reported that can be used as a support or as a bridge to lung transplant, with both short-term and long-term results. Thus, today in 2022, ECMO has emerged as a preferred modality of intraoperative support over conventional CPB.4 It was the reports of successful therapy of post graft dysfunction (PGD) with ECMO that prompted the use of ECMO intraoperatively. Currently, ECMO for lung transplant patients is the only rescue therapy to salvage a graft affected by severe PGD.
体外膜氧合(Extracorporeal membrane oxygenation, ECMO)在心肺移植的术前和术后管理中都有明确的作用。它在接受者身上用作移植的桥梁,直到器官可用为止。它在手术中作为部分体外循环提供了很好的支持。移植后,在急性排斥反应或术后发生移植物功能障碍时,它再次提供支持。当ECMO作为指征是继续提供支持。因此,ECMO对肺移植结果有积极影响在一项随机对照研究中,即2009年的CAESAR试验,ECMO被证实是ARDS的决定性现代治疗方法2,它在治疗成人ARDS中得到了普及。Veith等人在19773年报道可作为肺移植的支持或桥梁,有短期和长期的效果。因此,在2022年的今天,ECMO已成为一种优于传统cpmo的术中支持方式。4正是ECMO成功治疗移植后功能障碍(PGD)的报道促使了ECMO术中应用。目前,肺移植患者的ECMO是挽救严重PGD影响的移植物的唯一拯救疗法。
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引用次数: 0
A Trip Down the Memory Lane of Dr. Frank Gollan, an Achilles of Extracorporeal Oxygenation 弗兰克·戈兰医生的记忆之旅,体外氧合的阿喀琉斯
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1759807
Doniparthi Pradeep, Jaydeep Malakar
Abstract Every health care professional does his best for mankind, but handling a patient on extracorporeal circulation places cardiac surgeons, cardiac anesthetists, and perfusionists in a separate class of health professional altogether. This is a humble effort to reminisce the research work done by Dr. Frank Gollan since his instrumental time to the current day practice, without whom it is impossible to imagine open heart surgery and circulatory arrest.
每个医疗保健专业人员都尽其所能为人类服务,但处理体外循环病人时,心脏外科医生、心脏麻醉师和灌注师完全被划分为不同的医疗专业人员类别。这是对弗兰克·戈兰博士从他的仪器时代到现在的实践中所做的研究工作的一种谦卑的回忆,没有他,我们无法想象心脏直视手术和循环停止。
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引用次数: 0
Should We Implement Type and Screen Transfusion Policy in Pediatric Cardiac Surgery to Improve Patient Blood Management? 小儿心脏外科是否应该实施输血类型和筛选政策以改善患者血液管理?
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1759830
S. Datta
Bleeding during or after cardiac surgery is common in adults and associated with signi fi cant utilization of blood products. 1 There is very little evidence available on patient blood management in pediatric cardiac surgery. Children typically receive transfusions perioperatively for many reasons, including developmental alterations of their hemostatic sys-tem, hemodilution, and hypothermia with cardiopulmonary bypass, systemic anticoagulation, etc. The complexity of their surgical procedures, complex cardiopulmonary inter-actions, and risk for inadequate oxygen delivery and post-operative bleeding further contribute to blood product utilization in this vulnerable population. Till date, most of the blood centers in India follow blood typing and crossmatch policy as a part of pretransfusion testing to select the right blood for these patients. In this policy, patients are typed for their ABO/RhD and received red cell transfusions based on the antihuman globulin crossmatch results. However, in type and screen policy, the transfusion services perform ABO/RhD typing and a screen for atypical antibodies of the patient ’ s blood and plasma. A negative antibodyscreen signi fi es that the patient does not demonstrate any clinically signi fi cant antibodies and, therefore, only an immediate spin or abbreviated crossmatch is required. Because an immediate spin crossmatch is a fairly simple test, taking approxi-mately 10minutes in comparison to full crossmatch that takes around 45minutes, blood is available rather quickly if the need should arise. Since blood is not unnecessarily crossmatched and reserved for a patient who might not
心脏手术期间或手术后出血在成人中很常见,并与血液制品的大量使用有关。关于儿童心脏手术患者血液管理的证据很少。儿童围手术期接受输血的典型原因有很多,包括其止血系统的发育改变、血液稀释、低温伴体外循环、全身抗凝等。外科手术的复杂性、复杂的心肺相互作用以及供氧不足和术后出血的风险进一步促进了这一弱势人群的血液制品使用。迄今为止,印度的大多数血液中心都遵循血型和交叉配型政策,作为输血前检测的一部分,为这些患者选择合适的血液。在这项政策中,患者根据ABO/RhD进行分型,并根据抗人球蛋白交叉配型结果接受红细胞输注。然而,在血型和筛查政策中,输血服务部门执行ABO/RhD分型和筛查患者血液和血浆的非典型抗体。抗体筛查阴性表明患者未表现出任何临床显著的抗体,因此只需要立即进行自旋或短暂交叉配型。因为即时旋转交叉配型是一个相当简单的测试,大约需要10分钟,而完全交叉配型大约需要45分钟,如果需要的话,血液可以很快得到。因为血液不是不必要的交叉配型,留给可能不匹配的病人
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引用次数: 0
Transesophageal Echocardiography (TEE)-Guided Paravalvular Leak (PVL) Closure: Expanding Horizons Beyond Operating Room 经食道超声心动图(TEE)引导瓣旁漏(PVL)闭合:拓展手术室以外的视野
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1757369
Rashmi Singh, P. Kapoor
Paravalvular leak (PVL) is a common, yet challenging entity occurring due to dehiscence of the annular tissue around the prosthetic valve, resulting in regurgitation of blood retrogradely. Although any prosthetic valve can be subjected to the risk of developing PVL, it is most commonly reported with the mitral valve followed by the aortic valve. The incidence of mitral PVL is around 7 to 17%, whereas with the aortic valve it is 5 to 10%. Symptomology can vary from asymptomatic patients with mild PVL to disabling symptoms pertaining to heart failure and hemolysis. TEE plays a pivotal role in the overall assessment along with procedural guidance for their closure. Multiple two-dimensional (2D) imaging views are required to scan the entire sewing ring diameter of a prosthetic valve. Three-dimensional (3D) TEE can give crucial information such as the number, size, shape, and circumference of the defects. 3D mitral en face view can give anatomical localization of the defect. During the procedure, TEE can assist in the confirmation of the position of the guidewire through the defect and not through the prosthetic valve. It also helps to conform to the adequate positioning of the vascular plug device and unrestrictive movement of the native prosthetic heart valve. TEE when combined with fluoroscopy can help in real-time guidance of passage of the guidewire and transcatheter device in relation to the prosthetic valve. Recently, Ahmed et al have named this technology as “Fusion Technique,” where they have combined real-time 2D and 3D TEE with fluoroscopy to facilitate the closure of PVL. Now that the time of minimally invasive surgery has taken over conventional surgery and fast tracking and enhanced recovery after surgery (ERAS) is the need of the moment, percutaneous PVL closure is preferred over surgical PVL closure. A study done by Gakrinho et al showed that percutaneous PVL closure has a reasonable success rate along with a low complication rate and the results are comparable to surgical treatment in high-risk patients. We hereby share our experience of the successful closure of PVL via the transcatheter technique using various 2D and 3D techniques.
瓣旁漏(PVL)是一种常见的,但具有挑战性的实体,由于假体瓣膜周围的环状组织破裂,导致血液逆行反流。尽管任何人工瓣膜都有发生PVL的风险,但最常见的是二尖瓣,其次是主动脉瓣。二尖瓣PVL的发生率约为7 - 17%,而主动脉瓣的发生率为5 - 10%。症状可以从无症状的轻度PVL患者到与心力衰竭和溶血有关的致残症状。TEE在总体评估中发挥关键作用,并为其结束提供程序指导。需要多个二维(2D)成像视图来扫描假体瓣膜的整个缝纫环直径。三维TEE可以提供诸如缺陷的数量、大小、形状和周长等关键信息。三维二尖瓣正面图可以给出缺损的解剖定位。在手术过程中,TEE可以帮助确认导丝穿过缺损的位置,而不是穿过假体瓣膜的位置。它还有助于符合血管塞装置的适当定位和天然人工心脏瓣膜的无限制运动。TEE结合透视可以帮助实时引导导丝和经导管装置相对于假体瓣膜的通过。最近,Ahmed等人将这项技术命名为“融合技术”,他们将实时2D和3D TEE与透视相结合,以促进PVL的闭合。现在微创手术的时代已经取代了传统手术,快速跟踪和术后恢复(ERAS)是当下的需要,经皮PVL闭合优于手术PVL闭合。Gakrinho等研究表明,经皮PVL闭合成功率合理,并发症发生率低,在高危患者中的效果可与手术治疗相媲美。我们在此分享我们使用各种2D和3D技术通过经导管技术成功关闭PVL的经验。
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引用次数: 0
期刊
Journal of Cardiac Critical Care TSS
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