首页 > 最新文献

Journal of Cardiac Critical Care TSS最新文献

英文 中文
Beta-Adrenergic Blockade: Is It the Prudent Choice against Sympathetic Overdrive in Patients with Hypertension or Heart Failure? 肾上腺素能阻滞剂:是高血压或心力衰竭患者对抗交感神经过度亢进的审慎选择吗?
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1759804
H. Chopra, A. Pancholia, Bhupen N. Desai, A. Sinha, Dhammdeep C. Dabhade, S. Newale
Abstract The development of hypertension and heart failure is correlated with the hyperactivation of the sympathetic nervous system. Beta-blockers are often considered a good therapeutic option in such clinical scenarios. However, the choice of β-blocker is a concern because of certain aspects like associated metabolic disturbances with their usage. Metoprolol has been reported to have the potential to alleviate sympathetic overdrive in patients with hypertension and heart failure. S-Metoprolol is the chirally pure β-blocker with favorable pharmacological features, improved safety profile, and allied clinical advantages versus racemic metoprolol; given this, can it be an effective therapeutic option against sympathetic overdrive in patients with hypertension and/or heart failure is not fully recognized yet. In this review, we attempted to discuss the current facts around sympathetic overdrive linked with hypertension as well as heart failure and pertaining pharmacological intervention with a focus on β-blockers in these clinical situations with an emphasis on the likely beneficial role of S-metoprolol.
高血压和心力衰竭的发生与交感神经系统的过度激活有关。在这种临床情况下,β受体阻滞剂通常被认为是一种很好的治疗选择。然而,β受体阻滞剂的选择是一个问题,因为某些方面,如相关的代谢紊乱与他们的使用。据报道,美托洛尔有可能缓解高血压和心力衰竭患者的交感神经过度亢进。s -美托洛尔是手性纯β受体阻滞剂,与外消旋美托洛尔相比,具有良好的药理特性、更高的安全性和相关的临床优势;鉴于此,它能否成为高血压和/或心力衰竭患者交感神经过度亢进的有效治疗选择尚不完全清楚。在这篇综述中,我们试图讨论当前与高血压和心力衰竭相关的交感神经过度亢进和相关的药物干预,重点是β受体阻滞剂在这些临床情况下的作用,并强调s -美托洛尔可能的有益作用。
{"title":"Beta-Adrenergic Blockade: Is It the Prudent Choice against Sympathetic Overdrive in Patients with Hypertension or Heart Failure?","authors":"H. Chopra, A. Pancholia, Bhupen N. Desai, A. Sinha, Dhammdeep C. Dabhade, S. Newale","doi":"10.1055/s-0042-1759804","DOIUrl":"https://doi.org/10.1055/s-0042-1759804","url":null,"abstract":"Abstract The development of hypertension and heart failure is correlated with the hyperactivation of the sympathetic nervous system. Beta-blockers are often considered a good therapeutic option in such clinical scenarios. However, the choice of β-blocker is a concern because of certain aspects like associated metabolic disturbances with their usage. Metoprolol has been reported to have the potential to alleviate sympathetic overdrive in patients with hypertension and heart failure. S-Metoprolol is the chirally pure β-blocker with favorable pharmacological features, improved safety profile, and allied clinical advantages versus racemic metoprolol; given this, can it be an effective therapeutic option against sympathetic overdrive in patients with hypertension and/or heart failure is not fully recognized yet. In this review, we attempted to discuss the current facts around sympathetic overdrive linked with hypertension as well as heart failure and pertaining pharmacological intervention with a focus on β-blockers in these clinical situations with an emphasis on the likely beneficial role of S-metoprolol.","PeriodicalId":34567,"journal":{"name":"Journal of Cardiac Critical Care TSS","volume":"1 1","pages":"206 - 209"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81991257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pathophysiology and Management of Hypercoagulation in Infectious Diseases 感染性疾病高凝的病理生理学和管理
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1757370
A. Tandayam, MujtabaHussain Naqvi Syed, G. Kumar
Numerous systemic infections may have hypercoagulation as one of the complications, which may range from asymptomatic presentation of elevation of biochemical markers of coagulation such as that of fibrin and thrombin generation, to a much severe, symptomatic, life-threatening, disseminated intravascular coagulation (DIC), which results in the formation of thrombi in the microvasculature of various organs. This phenomenon contributes to increase in morbidity and mortality in various infectious diseases. The current review discusses various mechanisms of hypercoagulation during infections such as tissue factor activation, endothelial cell activation, inhibition of physiological anticoagulant pathways, and fibrinolysis inhibition. The review also discusses pathophysiological changes in the coagulation system and its management in the recent pandemic of COVID-19. The article also discusses role of various parenteral and oral anticoagulants in the management of infectious diseases. The review provides clinical data on various anticoagulants used during hospitalization and extended prophylaxis for the management of venous thromboembolism in various infections. Methodology Because this is a review of published literature and no humans or animals were involved, ethical committee approval was not required and patient consent was not required.
许多全身性感染可能以高凝作为并发症之一,其范围可能从无症状的凝血生化指标(如纤维蛋白和凝血酶生成)升高,到非常严重的、有症状的、危及生命的弥散性血管内凝血(DIC),导致各种器官微血管形成血栓。这一现象导致各种传染病的发病率和死亡率增加。目前的综述讨论了感染期间高凝的各种机制,如组织因子活化、内皮细胞活化、生理抗凝途径的抑制和纤维蛋白溶解抑制。本文还讨论了近期COVID-19大流行中凝血系统的病理生理变化及其管理。本文还讨论了各种肠外和口服抗凝剂在感染性疾病治疗中的作用。该综述提供了住院期间使用的各种抗凝剂的临床数据,并扩展了预防各种感染的静脉血栓栓塞的管理。由于这是对已发表文献的回顾,不涉及人类或动物,因此不需要伦理委员会的批准,也不需要患者的同意。
{"title":"Pathophysiology and Management of Hypercoagulation in Infectious Diseases","authors":"A. Tandayam, MujtabaHussain Naqvi Syed, G. Kumar","doi":"10.1055/s-0042-1757370","DOIUrl":"https://doi.org/10.1055/s-0042-1757370","url":null,"abstract":"Numerous systemic infections may have hypercoagulation as one of the complications, which may range from asymptomatic presentation of elevation of biochemical markers of coagulation such as that of fibrin and thrombin generation, to a much severe, symptomatic, life-threatening, disseminated intravascular coagulation (DIC), which results in the formation of thrombi in the microvasculature of various organs. This phenomenon contributes to increase in morbidity and mortality in various infectious diseases. The current review discusses various mechanisms of hypercoagulation during infections such as tissue factor activation, endothelial cell activation, inhibition of physiological anticoagulant pathways, and fibrinolysis inhibition. The review also discusses pathophysiological changes in the coagulation system and its management in the recent pandemic of COVID-19. The article also discusses role of various parenteral and oral anticoagulants in the management of infectious diseases. The review provides clinical data on various anticoagulants used during hospitalization and extended prophylaxis for the management of venous thromboembolism in various infections.\u0000 Methodology Because this is a review of published literature and no humans or animals were involved, ethical committee approval was not required and patient consent was not required.","PeriodicalId":34567,"journal":{"name":"Journal of Cardiac Critical Care TSS","volume":"125 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83998048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Role of Cerebral Oximetry in Extracorporeal Membrane Oxygenation 脑氧饱和度在体外膜氧合中的作用
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1757393
N. Shastri
Cerebral oximetry, which is based on near-infrared spectroscopy (NIRS) technology, is an optical technique that allows for noninvasive and continuous monitoring of brain oxygenation by determining cerebral tissue blood oxygen saturation. Many research and observational studies were performed with neonates using various types of NIRS/cerebral oximetry monitors. However, no food and drug administration (FDA) approved-cerebral oximeter is available for neonates. Successful validation of cerebral oximetry for the FDA has been done in human adult volunteer studies under protocols in which jugular bulb and arterial blood samples were obtained under different levels of fractional inspired oxygen levels.
脑血氧仪是一种基于近红外光谱(NIRS)技术的光学技术,可以通过测定脑组织血氧饱和度来实现对脑氧合的无创和连续监测。许多研究和观察性研究使用不同类型的NIRS/脑氧饱和度监测仪对新生儿进行。然而,没有食品和药物管理局(FDA)批准的脑血氧仪可用于新生儿。美国食品药品监督管理局(FDA)在成人志愿者研究中成功验证了脑血氧仪的有效性,研究方案是在不同分数吸入氧水平下获得颈静脉和动脉血液样本。
{"title":"Role of Cerebral Oximetry in Extracorporeal Membrane Oxygenation","authors":"N. Shastri","doi":"10.1055/s-0042-1757393","DOIUrl":"https://doi.org/10.1055/s-0042-1757393","url":null,"abstract":"Cerebral oximetry, which is based on near-infrared spectroscopy (NIRS) technology, is an optical technique that allows for noninvasive and continuous monitoring of brain oxygenation by determining cerebral tissue blood oxygen saturation. Many research and observational studies were performed with neonates using various types of NIRS/cerebral oximetry monitors. However, no food and drug administration (FDA) approved-cerebral oximeter is available for neonates. Successful validation of cerebral oximetry for the FDA has been done in human adult volunteer studies under protocols in which jugular bulb and arterial blood samples were obtained under different levels of fractional inspired oxygen levels.","PeriodicalId":34567,"journal":{"name":"Journal of Cardiac Critical Care TSS","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91075233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Splenic Artery Pseudoaneurysm—A Concern for the Anesthesiologist 脾动脉假性动脉瘤——麻醉师应关注的问题
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1756472
Ankita Singh, N. Makhija, Shruti K. Somani, M. Verma, Sanjeev Kumar
Pseudoaneurysms as compared with aneurysms lack a true wall and have a higher propensity of rupture. Visceral artery pseudoaneurysms are uncommon and are life-threatening. We, hereby, report anesthetic management of a rare case of splenic artery pseudoaneurysm that accompanied the dilatation of aorta from its origin extending up to its bifurcation.
假性动脉瘤与缺乏真壁的动脉瘤相比,有较高的破裂倾向。内脏动脉假性动脉瘤并不常见,且危及生命。在此,我们报告一例罕见的脾动脉假性动脉瘤的麻醉处理,伴随著主动脉从其起源延伸到其分叉的扩张。
{"title":"Splenic Artery Pseudoaneurysm—A Concern for the Anesthesiologist","authors":"Ankita Singh, N. Makhija, Shruti K. Somani, M. Verma, Sanjeev Kumar","doi":"10.1055/s-0042-1756472","DOIUrl":"https://doi.org/10.1055/s-0042-1756472","url":null,"abstract":"Pseudoaneurysms as compared with aneurysms lack a true wall and have a higher propensity of rupture. Visceral artery pseudoaneurysms are uncommon and are life-threatening. We, hereby, report anesthetic management of a rare case of splenic artery pseudoaneurysm that accompanied the dilatation of aorta from its origin extending up to its bifurcation.","PeriodicalId":34567,"journal":{"name":"Journal of Cardiac Critical Care TSS","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78947510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrospective Analysis of Arterial Carbon Dioxide Level and Arterial pH Level at the Time of Initiation of Respiratory ECMO and Outcome 呼吸性ECMO开始时动脉二氧化碳水平和动脉pH水平及结果的回顾性分析
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1757395
Pranay Oza, Rajendra Umbarkar, V. Goyal, P. Shukla
Introduction Respiratory extracorporeal membrane oxygenation (ECMO) is well established and its popularity has increased during coronavirus disease 2019 (COVID-19) time. The efficacy of ECMO has been proved in refractory respiratory failure with varied etiology. More than 85,000 respiratory ECMO cases (neonatal, pediatric, adult) registered as per Extracorporeal Life support Organization (ELSO) statistics April 2022 report, with survived to discharge or transfer ranging from 58 to 73%. Early initiation of ECMO is usually associated with shorter ECMO run and better outcome. Many patient factors have been associated with mortality while on ECMO. Pre-ECMO patient pH and arterial partial pressure of carbon dioxide (paCO2) have been associated with poor outcome. We designed a retrospective study from a single tertiary care center and analyzed our data of all respiratory ECMO (neonatal, pediatric, and adult) to understand the effect of pre ECMO, paCO2, and arterial pH to ECMO outcome. Methods It is a retrospective analysis of data collected of patients with acute respiratory failure managed on ECMO from January 2010 to December 2021. Pre-ECMO (1–6 hours before initiation), paCO2, and arterial pH level were noted and analyzed with primary and secondary outcome. Primary outcome goal was survivor and discharged home versus nonsurvivor, while secondary goal was the number of ECMO days and incidence of neurological complications. The statistical analysis was done for primary outcome and incidences of neurological complications and p-value obtained by using chi-squared method. Meta-analysis was done by classifying the respiratory ECMO cases in three major category—COVID-19, H1N1 non-COVID-19, and H1N1 respiratory failure. Results The total 256 patients of respiratory failure were treated with ECMO during specified period by Riddhi Vinayak Multispecialty Hospital ECMO team. Data analysis of 251 patients (5 patients were transferred for lung transplant, hence been not included in study) done. Patients were divided on the basis of pH level less than 7.2 and more than 7.2 and analyzed for primary and secondary outcome. Similarly, patients were divided on the basis of paCO2 level of less than 45 and more than 45.Patient with pre-ECMO pH level more than 7.2 has statistically better survived extracorporeal life support (ECLS) (p-value: 0.008) and survival to discharge home (p-value: 0.038) chances. Pre-ECMO paCO2 level of less than 45 also showed better survival chance of survived ECLS (46.67 vs. 36.02) and survived to discharge home (42.22 vs. 31.06) but not statistically significant (p-value: 0.15 and 0.18, respectively). There was no significant difference in average number of ECMO days in patient survived to discharge home with paCO2 less than 45 and more than 45 (15.7 vs. 11.1 days), and also in pH more than 7.2 and pH less than 7.2 (15.8 vs. 11.6). The incidence of neurological complications was also found lower in patient with pH more than 7.2 (7.5 vs. 1
在2019冠状病毒病(COVID-19)期间,呼吸体外膜氧合(ECMO)已经建立并普及。ECMO治疗各种病因的难治性呼吸衰竭的疗效已得到证实。根据体外生命支持组织(ELSO) 2022年4月的统计报告,超过85,000例呼吸ECMO病例(新生儿,儿童,成人)登记,存活至出院或转移的比例为58%至73%。早期开始ECMO通常与较短的ECMO运行时间和较好的结果相关。许多患者因素与体外氧合时的死亡率有关。ecmo前患者的pH值和动脉二氧化碳分压(paCO2)与不良预后相关。我们设计了一项来自单一三级护理中心的回顾性研究,并分析了所有呼吸系统ECMO(新生儿、儿童和成人)的数据,以了解ECMO前、paCO2和动脉pH对ECMO结果的影响。方法回顾性分析2010年1月至2021年12月ECMO治疗急性呼吸衰竭患者的资料。记录ecmo前(开始前1-6小时)、paCO2和动脉pH水平,并分析其主要和次要结局。主要结局目标是幸存者和出院回家与非幸存者的比较,而次要目标是ECMO天数和神经系统并发症的发生率。对主要结局和神经系统并发症发生率进行统计学分析,p值采用卡方法。将呼吸道ECMO病例分为covid -19、H1N1非covid -19和H1N1呼吸衰竭3大类进行meta分析。结果共有256例呼吸衰竭患者在规定的时间内接受了Riddhi Vinayak多专科医院ECMO组的ECMO治疗。对251例患者进行了数据分析(其中5例患者转行肺移植,因此未纳入研究)。根据pH值小于7.2和大于7.2进行分组,分析主要和次要结局。同样,根据paCO2水平小于45和大于45分患者。ecmo前pH值大于7.2的患者体外生命支持(ECLS)存活(p值:0.008)和出院回家存活(p值:0.038)的机会有统计学意义。ecmo前paCO2水平低于45的患者ECLS存活几率(46.67比36.02)和出院几率(42.22比31.06)也更高,但p值分别为0.15和0.18,差异无统计学意义。paCO2小于45和大于45的患者存活至出院的ECMO平均天数(15.7天vs 11.1天),以及pH大于7.2和小于7.2的患者(15.8天vs 11.6天)无显著差异。pH > 7.2 (7.5 vs. 17.3%, p值:0.034)和paCO2 < 45 (4.4 vs. 12.65, p值:0.15)患者神经系统并发症发生率较低。结论ecmo前动脉pH > 7.2(有统计学意义)、paCO2 < 45(无统计学意义)患者的生存几率明显提高,神经系统并发症发生率明显降低。两组患者ECMO天数差异无统计学意义。作者建议尽早开始ECMO以降低死亡率和发病率。
{"title":"Retrospective Analysis of Arterial Carbon Dioxide Level and Arterial pH Level at the Time of Initiation of Respiratory ECMO and Outcome","authors":"Pranay Oza, Rajendra Umbarkar, V. Goyal, P. Shukla","doi":"10.1055/s-0042-1757395","DOIUrl":"https://doi.org/10.1055/s-0042-1757395","url":null,"abstract":"\u0000 Introduction Respiratory extracorporeal membrane oxygenation (ECMO) is well established and its popularity has increased during coronavirus disease 2019 (COVID-19) time. The efficacy of ECMO has been proved in refractory respiratory failure with varied etiology. More than 85,000 respiratory ECMO cases (neonatal, pediatric, adult) registered as per Extracorporeal Life support Organization (ELSO) statistics April 2022 report, with survived to discharge or transfer ranging from 58 to 73%. Early initiation of ECMO is usually associated with shorter ECMO run and better outcome. Many patient factors have been associated with mortality while on ECMO. Pre-ECMO patient pH and arterial partial pressure of carbon dioxide (paCO2) have been associated with poor outcome. We designed a retrospective study from a single tertiary care center and analyzed our data of all respiratory ECMO (neonatal, pediatric, and adult) to understand the effect of pre ECMO, paCO2, and arterial pH to ECMO outcome.\u0000 Methods It is a retrospective analysis of data collected of patients with acute respiratory failure managed on ECMO from January 2010 to December 2021. Pre-ECMO (1–6 hours before initiation), paCO2, and arterial pH level were noted and analyzed with primary and secondary outcome. Primary outcome goal was survivor and discharged home versus nonsurvivor, while secondary goal was the number of ECMO days and incidence of neurological complications. The statistical analysis was done for primary outcome and incidences of neurological complications and p-value obtained by using chi-squared method. Meta-analysis was done by classifying the respiratory ECMO cases in three major category—COVID-19, H1N1 non-COVID-19, and H1N1 respiratory failure.\u0000 Results The total 256 patients of respiratory failure were treated with ECMO during specified period by Riddhi Vinayak Multispecialty Hospital ECMO team. Data analysis of 251 patients (5 patients were transferred for lung transplant, hence been not included in study) done. Patients were divided on the basis of pH level less than 7.2 and more than 7.2 and analyzed for primary and secondary outcome. Similarly, patients were divided on the basis of paCO2 level of less than 45 and more than 45.Patient with pre-ECMO pH level more than 7.2 has statistically better survived extracorporeal life support (ECLS) (p-value: 0.008) and survival to discharge home (p-value: 0.038) chances. Pre-ECMO paCO2 level of less than 45 also showed better survival chance of survived ECLS (46.67 vs. 36.02) and survived to discharge home (42.22 vs. 31.06) but not statistically significant (p-value: 0.15 and 0.18, respectively). There was no significant difference in average number of ECMO days in patient survived to discharge home with paCO2 less than 45 and more than 45 (15.7 vs. 11.1 days), and also in pH more than 7.2 and pH less than 7.2 (15.8 vs. 11.6). The incidence of neurological complications was also found lower in patient with pH more than 7.2 (7.5 vs. 1","PeriodicalId":34567,"journal":{"name":"Journal of Cardiac Critical Care TSS","volume":"71 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86573934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Papillary Muscle Rupture following Acute Myocardial Infarction 急性心肌梗死后乳头肌破裂
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1759803
Ajmer Singh, C. Nanda, Y. Mehta
Abstract Rupture of a papillary muscle after acute myocardial infarction is a rare but potentially fatal complication. It can lead to acute, severe mitral regurgitation, pulmonary edema, cardiogenic shock, and death. Immediate surgical intervention in the form of mitral valve repair/replacement with concomitant coronary revascularization can reduce mortality. We herein report such a case who presented with cardiogenic shock and made a successful outcome after emergent surgery.
摘要急性心肌梗死后乳头状肌破裂是一种罕见但可能致命的并发症。它可导致急性严重二尖瓣反流、肺水肿、心源性休克和死亡。立即进行二尖瓣修复/置换术并合并冠状动脉血运重建术可以降低死亡率。我们在此报告这样一个病例谁提出心源性休克,并取得了成功的结果后紧急手术。
{"title":"Papillary Muscle Rupture following Acute Myocardial Infarction","authors":"Ajmer Singh, C. Nanda, Y. Mehta","doi":"10.1055/s-0042-1759803","DOIUrl":"https://doi.org/10.1055/s-0042-1759803","url":null,"abstract":"Abstract Rupture of a papillary muscle after acute myocardial infarction is a rare but potentially fatal complication. It can lead to acute, severe mitral regurgitation, pulmonary edema, cardiogenic shock, and death. Immediate surgical intervention in the form of mitral valve repair/replacement with concomitant coronary revascularization can reduce mortality. We herein report such a case who presented with cardiogenic shock and made a successful outcome after emergent surgery.","PeriodicalId":34567,"journal":{"name":"Journal of Cardiac Critical Care TSS","volume":"60 1","pages":"230 - 232"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87114903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plugging the Unplugged: Simultaneous Percutaneous Closure of Anterior Mitral Leaflet and Aortic Root Perforation 堵塞未堵塞:同时经皮缝合二尖瓣前小叶和主动脉根部穿孔
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1756471
C. Nanda, Sudipto Banerjee, Y. Mehta
There are very few case reports of percutaneous device closure of anterior mitral leaflet perforation. We describe here a case of simultaneous percutaneous closure of aortic root perforation and anterior mitral perforation. These cases are challenging as they are presently done in high-risk patients with no guidelines described to date.
有很少的病例报告经皮装置关闭前二尖瓣小叶穿孔。我们在这里描述一个同时经皮缝合主动脉根部穿孔和前二尖瓣穿孔的病例。这些病例具有挑战性,因为它们目前在高风险患者中进行,迄今尚无指南描述。
{"title":"Plugging the Unplugged: Simultaneous Percutaneous Closure of Anterior Mitral Leaflet and Aortic Root Perforation","authors":"C. Nanda, Sudipto Banerjee, Y. Mehta","doi":"10.1055/s-0042-1756471","DOIUrl":"https://doi.org/10.1055/s-0042-1756471","url":null,"abstract":"There are very few case reports of percutaneous device closure of anterior mitral leaflet perforation. We describe here a case of simultaneous percutaneous closure of aortic root perforation and anterior mitral perforation. These cases are challenging as they are presently done in high-risk patients with no guidelines described to date.","PeriodicalId":34567,"journal":{"name":"Journal of Cardiac Critical Care TSS","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79686661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does Preoperative Plasma Endothelin-1 Level Influences the Postoperative Events in Patients Undergoing Coronary Artery Bypass Grafting (CABG)? Revisiting Endothelin-1 Molecule in CABG Patients 术前血浆内皮素-1水平是否影响冠状动脉搭桥术(CABG)患者术后事件?CABG患者内皮素-1分子的研究
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1757362
Minati Choudhury, M. Hote, P. Kapoor, S. Saini, U. Kiran
Endothelin-1 (ET-1) is a powerful physiological vasoconstrictor release in response to endothelial injury. Increased synthesis of endothelin is associated with myocardial ischemia and reperfusion injury. The normal level varies between 0.2 and 18.5 pg/mL that maintains normal vascular homeostasis. We hypothesized that there exists a correlation between ET-1 and clinical outcome in patient undergoing elective coronary artery bypass grafting (CABG) surgery under cardiopulmonary bypass.Fifty-eight patients undergoing elective on-pump CABG were enrolled in the study. Blood sample for plasma ET-1 was taken before anesthesia induction. The median ET-1 level was 5 pg/mL (range: 0.6–30.33 pg/mL). The inotropic and intraaortic balloon pump requirement was significantly higher among patients having baseline ET-1 level more than 14.24pg/mL (p = 0.001in each case). A similar finding was observed in the duration of mechanical ventilation, intensive care unit stay, and duration of hospital stay (r = 0.68, p = 0.000; r = 0.58, p = 0.000; and r = 0.61, p = 0.000 respectively). The occurrence of complications was also more in individuals with higher baseline ET-1 level. The p-value was significant for occurrence infection, arrhythmia, renal and respiratory problems as observed in postoperative period by using Mann–Whitney U test.This study concludes that higher level of preoperative ET-1 levels correlates well to adverse clinical outcome in patients undergoing on-pump CABG surgery, so herein it can be used as a single independent parameter to predict postoperative outcome.
内皮素-1 (ET-1)是一种强大的生理血管收缩剂,是对内皮损伤的反应。内皮素合成增加与心肌缺血再灌注损伤有关。正常水平在0.2 - 18.5 pg/mL之间,维持正常的血管稳态。我们假设体外循环下择期冠状动脉旁路移植术(CABG)患者的ET-1与临床结果存在相关性。58名接受选择性非泵式冠脉搭桥的患者参加了这项研究。麻醉诱导前采血检测血浆ET-1。ET-1中位水平为5 pg/mL(范围:0.6-30.33 pg/mL)。基线ET-1水平高于14.24pg/mL的患者,肌力和主动脉内球囊泵的需求明显更高(p = 0.001)。在机械通气时间、重症监护病房住院时间和住院时间方面也有类似的发现(r = 0.68, p = 0.000;R = 0.58, p = 0.000;r = 0.61, p = 0.000)。ET-1基线水平较高的患者并发症发生率也较高。Mann-Whitney U检验观察术后感染、心律失常、肾脏及呼吸问题的发生p值均有显著性意义。本研究认为无泵搭桥患者术前较高的ET-1水平与不良临床结局相关,可作为预测术后预后的单一独立参数。
{"title":"Does Preoperative Plasma Endothelin-1 Level Influences the Postoperative Events in Patients Undergoing Coronary Artery Bypass Grafting (CABG)? Revisiting Endothelin-1 Molecule in CABG Patients","authors":"Minati Choudhury, M. Hote, P. Kapoor, S. Saini, U. Kiran","doi":"10.1055/s-0042-1757362","DOIUrl":"https://doi.org/10.1055/s-0042-1757362","url":null,"abstract":"Endothelin-1 (ET-1) is a powerful physiological vasoconstrictor release in response to endothelial injury. Increased synthesis of endothelin is associated with myocardial ischemia and reperfusion injury. The normal level varies between 0.2 and 18.5 pg/mL that maintains normal vascular homeostasis. We hypothesized that there exists a correlation between ET-1 and clinical outcome in patient undergoing elective coronary artery bypass grafting (CABG) surgery under cardiopulmonary bypass.Fifty-eight patients undergoing elective on-pump CABG were enrolled in the study. Blood sample for plasma ET-1 was taken before anesthesia induction. The median ET-1 level was 5 pg/mL (range: 0.6–30.33 pg/mL). The inotropic and intraaortic balloon pump requirement was significantly higher among patients having baseline ET-1 level more than 14.24pg/mL (p = 0.001in each case). A similar finding was observed in the duration of mechanical ventilation, intensive care unit stay, and duration of hospital stay (r = 0.68, p = 0.000; r = 0.58, p = 0.000; and r = 0.61, p = 0.000 respectively). The occurrence of complications was also more in individuals with higher baseline ET-1 level. The p-value was significant for occurrence infection, arrhythmia, renal and respiratory problems as observed in postoperative period by using Mann–Whitney U test.This study concludes that higher level of preoperative ET-1 levels correlates well to adverse clinical outcome in patients undergoing on-pump CABG surgery, so herein it can be used as a single independent parameter to predict postoperative outcome.","PeriodicalId":34567,"journal":{"name":"Journal of Cardiac Critical Care TSS","volume":"172 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79514265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Redo Mitral Valve Replacement Using St. Jude Medical Mechanical Prosthesis via Transseptal Approach in a Patient with Degenerated Mitral Epic Bioprosthesis: A Video Presentation 圣犹达医疗机械假体经鼻中隔入路治疗二尖瓣生物假体退行性变患者:录像报告
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1757365
S. Goja, Niwin George, L. Sankhyan, Sumanth Raghuprakash, Shradha Gupta, Shweta Sharma, P. Kapoor, U. Chowdhury
A 58-year-old male patient with degenerated St. Jude Epic mitral bioprosthesis underwent successful mitral valve replacement using 29 mm St. Jude Medical mechanical prosthesis. Case history presented here to prevent organ injury via a transeptal approach for a degenerated epic bioprosthesis.
一位58岁的St. Jude Epic生物假体退行性二尖瓣置换术的男性患者使用29毫米St. Jude Medical机械假体成功置换术。本文介绍了通过经间隔入路治疗退行性史诗生物假体以防止器官损伤的病例。
{"title":"Redo Mitral Valve Replacement Using St. Jude Medical Mechanical Prosthesis via Transseptal Approach in a Patient with Degenerated Mitral Epic Bioprosthesis: A Video Presentation","authors":"S. Goja, Niwin George, L. Sankhyan, Sumanth Raghuprakash, Shradha Gupta, Shweta Sharma, P. Kapoor, U. Chowdhury","doi":"10.1055/s-0042-1757365","DOIUrl":"https://doi.org/10.1055/s-0042-1757365","url":null,"abstract":"A 58-year-old male patient with degenerated St. Jude Epic mitral bioprosthesis underwent successful mitral valve replacement using 29 mm St. Jude Medical mechanical prosthesis. Case history presented here to prevent organ injury via a transeptal approach for a degenerated epic bioprosthesis.","PeriodicalId":34567,"journal":{"name":"Journal of Cardiac Critical Care TSS","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75345749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ankle Block for Acute Pain Management in a Patient with Mitral Valve Prolapse and Infective Endocarditis with Dry Gangrene of Toes 二尖瓣脱垂合并感染性心内膜炎伴干性趾坏疽患者的踝部阻滞治疗急性疼痛
Pub Date : 2022-07-01 DOI: 10.1055/s-0042-1759808
Sambhunath Das, M. Prakash, Vishnu Anandan
Abstract Ankle block represents a regional anesthesia technique to provide anesthesia for the procedures related to the foot. It is mainly used as a sole anesthesia technique or as an adjunct for postoperative pain relief in foot operations. It is an infiltrative block with advantages like being technically easier, safe, having minimal side effects, and having a high success rate. Management of postoperative pain is an essential service provided by a cardiac anesthesiologist to patients undergoing operative procedures, but the knowledge in providing regional anesthesia may be used beyond the operating room or critical care unit. In the present case, we administered an ankle block to alleviate the pain in case of dry gangrene.
踝关节阻滞是一种为足部相关手术提供麻醉的区域麻醉技术。它主要用作足底麻醉技术或作为足部手术后疼痛缓解的辅助手段。它是一种渗透性阻断,具有技术上更简单、安全、副作用最小、成功率高等优点。术后疼痛管理是心脏麻醉师为手术患者提供的一项基本服务,但提供区域麻醉的知识可能会在手术室或重症监护病房之外使用。在本病例中,我们使用踝部阻滞来缓解干性坏疽的疼痛。
{"title":"Ankle Block for Acute Pain Management in a Patient with Mitral Valve Prolapse and Infective Endocarditis with Dry Gangrene of Toes","authors":"Sambhunath Das, M. Prakash, Vishnu Anandan","doi":"10.1055/s-0042-1759808","DOIUrl":"https://doi.org/10.1055/s-0042-1759808","url":null,"abstract":"Abstract Ankle block represents a regional anesthesia technique to provide anesthesia for the procedures related to the foot. It is mainly used as a sole anesthesia technique or as an adjunct for postoperative pain relief in foot operations. It is an infiltrative block with advantages like being technically easier, safe, having minimal side effects, and having a high success rate. Management of postoperative pain is an essential service provided by a cardiac anesthesiologist to patients undergoing operative procedures, but the knowledge in providing regional anesthesia may be used beyond the operating room or critical care unit. In the present case, we administered an ankle block to alleviate the pain in case of dry gangrene.","PeriodicalId":34567,"journal":{"name":"Journal of Cardiac Critical Care TSS","volume":"57 1","pages":"233 - 234"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89143427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Cardiac Critical Care TSS
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1