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Tic & Tourette Syndrome and Motor Disorders 抽动秽语综合征和运动障碍
Pub Date : 2016-02-01 DOI: 10.7599/HMR.2016.36.1.46
T. Park, Juhyun Park
Motor disorder refers to neuropsychiatric disorders such as abnormal movements, meaningless repetitive movements, and impairment in acquisition and performance of motor skills. Motor disorder was included as a sub-category of neurodevelopmental disorder chapter in the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) [1]. DSM-5’s motor disorders include tic disorders (Tourette’s disorder, persistent motor or vocal tic disorder, provisional tic disorder, other specified tic disorder, and unspecified tic disorder), developmental coordination disorder, and stereotypic movement disorder. This review overviews and summarizes current knowledge on the motor disorder’s cause, diagnosis, and treatment. TIC DISORDERS
运动障碍是指神经精神障碍,如异常运动,无意义的重复运动,以及运动技能的习得和表现障碍。《精神障碍诊断与统计手册》第5版(DSM-5)[1]将运动障碍作为神经发育障碍章节的一个子类别。DSM-5的运动障碍包括抽动障碍(抽动障碍,持续性运动或声音抽动障碍,暂时性抽动障碍,其他特定的抽动障碍和未指定的抽动障碍),发育协调障碍和刻板运动障碍。这篇综述概述和总结了目前关于运动障碍的病因、诊断和治疗的知识。国际资本流动障碍
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引用次数: 1
Psychological Assessment in Neurodevelopmental Disorders 神经发育障碍的心理评估
Pub Date : 2016-02-01 DOI: 10.7599/HMR.2016.36.1.72
M. Oh
Neurodevelopmental disorders are characterized by impaired development that causes adjustment problems. The spectrum of developmental impairment varies and includes in- tellectual disabilities, communication and social interaction challenges, and attention and executive function deficits. The neurodevelopmental disorders include intellectual disabil- ity, communication disorder, autism spectrum disorder, attention-deficit/hyperactivity dis- order, neurodevelopmental motor disorders, and specific learning disorder. The differential diagnosis of neurodevelopmental disorders is important, comprehensive psychological assessmentsare required for individuals who may have a neurodevelopmental disorder. This paper focuses on intellectual, neuropsychological, adaptive behavior, and autism di- agnostic assessments and psychiatric comorbidities. These assessments accurately screen for neurodevelopmental disorders and aid in differential diagnosis. The goals of psycho- logical assessment include facilitating therapeutic planning, and suggesting prognosis. Further research is required to clarify each aspect of neurodevelopmental disorders and optimize psychological assessment tools accordingly.
神经发育障碍的特点是发育受损,导致适应问题。发育障碍的范围各不相同,包括智力障碍、沟通和社会互动障碍、注意力和执行功能缺陷。神经发育障碍包括智力障碍、交流障碍、自闭症谱系障碍、注意力缺陷/多动障碍、神经发育运动障碍和特定学习障碍。神经发育障碍的鉴别诊断是重要的,对可能患有神经发育障碍的个体需要进行全面的心理评估。本文的重点是智力、神经心理学、适应性行为和自闭症诊断评估和精神合并症。这些评估准确地筛选神经发育障碍,并有助于鉴别诊断。心理评估的目的包括促进治疗计划和提示预后。需要进一步的研究来阐明神经发育障碍的各个方面,并相应地优化心理评估工具。
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引用次数: 2
Neurodevelopmental Outcome of Preterm Infants at Childhood: Cognition and Language 早产儿在儿童期的神经发育结局:认知和语言
Pub Date : 2016-02-01 DOI: 10.7599/HMR.2016.36.1.55
H. J. Lee, Hyun Kyung Park
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引用次数: 7
Socially Assistive Robotics in Autism Spectrum Disorder 自闭症谱系障碍中的社交辅助机器人
Pub Date : 2016-02-01 DOI: 10.7599/HMR.2016.36.1.17
Seong Jin Cho, D. Ahn
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引用次数: 23
Brain Stimulation and Modulation for Autism Spectrum Disorder 自闭症谱系障碍的脑刺激和调节
Pub Date : 2016-02-01 DOI: 10.7599/HMR.2016.36.1.65
T. Kim, Jimi Ryu, G. Bahn
Autism spectrum disorder (ASD) is characterized by a range of conditions including impairments in social interaction, communication, and restricted and repetitive behaviors. Pharmacological treatments can improve some symptoms of ASD, but the effect is limited and there is a huge unmet demand for successful interventions of ASD. Brain stimulation and modulation are emerging treatment options for ASD: electroconvulsive therapy for catatonia in ASD, vagal nerve stimulation for comorbid epilepsy and ASD, and deep brain stimulation for serious self-injurious behavior. Therapeutic tools are evolving to mechanism-driven treatment. Excitation/Inhibition (E/I) imbalance alters the brain mechanism of information processing and behavioral regulation. Repetitive transcranial magnetic stimulation can stabilize aberrant neuroplasticity by improving E/I balance. These brain stimulation and modulation methods are expected to be used for exploration of the pathophysiology and etiology of ASD and might facilitate the development of a mechanism-driven solution of core domains of ASD in the future.
自闭症谱系障碍(ASD)的特点是一系列的情况,包括社会互动,沟通障碍,限制和重复行为。药物治疗可以改善ASD的一些症状,但效果有限,而且对ASD的成功干预还有巨大的未满足的需求。脑刺激和调节是ASD的新兴治疗选择:电痉挛治疗ASD中的紧张症,迷走神经刺激治疗共病癫痫和ASD,深部脑刺激治疗严重自残行为。治疗工具正在演变为机制驱动的治疗。兴奋/抑制(E/I)失衡改变了大脑的信息加工和行为调节机制。反复经颅磁刺激可通过改善E/I平衡来稳定异常的神经可塑性。这些脑刺激和调节方法有望用于探索ASD的病理生理学和病因学,并可能促进未来ASD核心领域机制驱动的解决方案的发展。
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引用次数: 4
Life Persistence of Attention-Deficit/Hyperactivity Disorder 注意缺陷/多动障碍的生命持续性
Pub Date : 2016-02-01 DOI: 10.7599/HMR.2016.36.1.38
A. Min, D. Ahn
This paper is to review Attention Deficit-Hyperactivity Disorder (ADHD) in the developmental perspective, focusing on clinical features, diagnosis and treatment of ADHD throughout life stage. When diagnosed with ADHD, before entering elementary school early diagnosis and early intervention is encouraged to reduce various impairments that occur during development. Thirty to eighty percent of school-age ADHD symptoms remain throughout the adolescence or meet the ADHD diagnosis criteria. During adolescence, hyperactivity and impulsiveness from other existing symptoms become less severe but children have insufficiency to continue studying or task compared to their peers. Pharmacologic treatment had been shown to be the most effective treatment regimen for adolescents who continue to have ADHD symptoms. In adults, representative symptoms of ADHD, hyperactivity and impulsiveness, often gradually decrease while lack of concentration remains. As Conner's Adult ADHD Diagnostic Interview for DSM-IV (CAADID), a structured interview for the diagnosis of adulthood ADHD has been translated into Korean, it can be applied clinically. Pharmacological and nonpharmacological treatment in adults had been shown to be effective.
本文从发展的角度对注意力缺陷多动障碍(ADHD)进行综述,重点介绍ADHD的临床特征、诊断和治疗。当被诊断为多动症时,在进入小学之前,鼓励早期诊断和早期干预,以减少在发展过程中发生的各种损害。30%到80%的学龄ADHD症状会持续到整个青春期,或者符合ADHD的诊断标准。在青少年时期,其他症状的多动和冲动变得不那么严重,但与同龄人相比,儿童无法继续学习或完成任务。药物治疗已被证明是对持续有ADHD症状的青少年最有效的治疗方案。在成人中,多动症的典型症状,多动和冲动,往往逐渐减少,但注意力不集中。作为诊断成人ADHD的结构化访谈,《Conner’s Adult ADHD Diagnostic Interview for DSM-IV》(CAADID)已被翻译成韩文,可以应用于临床。成人的药物和非药物治疗已被证明是有效的。
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引用次数: 3
Cerebral Palsy Update - Focusing on the Treatments and Interventions 脑瘫最新进展-关注治疗和干预措施
Pub Date : 2016-02-01 DOI: 10.7599/HMR.2016.36.1.59
M. Kim
Cerebral palsy (CP), known as “Little’s disease” is the most common neurologic disorder in pediatric patients. The core problem of CP is the abnormal movement and posture which manifests very early in the development. The cornerstone to treat the children with CP is the conventional rehabilitation program based on neurodevelopmental approach that has been done for decades. Recently, various translational research has emerged, and focused on the changing therapeutic paradigm using high technologic equipment such as computer- or robotic-approach, botulinum toxin, or stem cell use with potential therapeutic effect. Many other trials using newly developed devices, or combination of old and new therapies are ongoing to demonstrate the evidence, however obstacles still remain. Regarding rehabilitative therapy, the use of exercise-based treatment such as early intervention, gross motor task training, hippotherapy, reactive balance training, treadmill training with/without body weight support, and trunk-targeted training are promising. Virtual reality, robot-assisted and computer-enhanced therapies are very potent therapeutic tools for CP under way of mass commercialization. Regarding medical therapy, botulinum toxin injection showed the most concrete benefit for CP children. Stem cell therapy is just beginning, performing experimental studies in vivo. The author reviewed the current research, expanding therapeutic options to improve the posture and movement control in children with CP.
脑瘫(CP),被称为“利特氏病”,是儿科患者中最常见的神经系统疾病。脑瘫的核心问题是在发育早期就表现出来的异常动作和姿势。治疗儿童脑瘫的基石是基于神经发育方法的传统康复计划,这已经进行了几十年。最近,各种转化研究已经出现,并集中于改变治疗范式,使用高科技设备,如计算机或机器人方法,肉毒杆菌毒素,或干细胞使用具有潜在的治疗效果。许多其他使用新开发设备或新旧疗法结合的试验正在进行中,以证明证据,但仍然存在障碍。关于康复治疗,使用基于运动的治疗,如早期干预、大运动任务训练、海马疗法、反应性平衡训练、有/没有体重支持的跑步机训练和躯干目标训练是有希望的。虚拟现实,机器人辅助和计算机增强治疗是非常有效的治疗工具的CP正在大规模商业化。在药物治疗方面,注射肉毒杆菌毒素对CP患儿的疗效最为明显。干细胞治疗才刚刚开始,在体内进行实验研究。作者回顾了目前的研究,扩大治疗方案,以改善儿童的姿势和运动控制的CP。
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引用次数: 4
Psychosocial Treatments for Children with Autism Spectrum Disorder 自闭症谱系障碍儿童的社会心理治疗
Pub Date : 2016-02-01 DOI: 10.7599/HMR.2016.36.1.27
Hyunsook Kim
Given the situation where various psychosocial treatments for autism spectrum disorder (ASD) are proposed and body of treatment outcome studies for ASD are accumulated, this study purported to review psychosocial treatments for children with ASD that currently receive empirical supports. To address these purposes, the study focused on the three types of psychosocial treatments frequently observed in ASD literature (behavioral interventions, social-communication skills interventions, and parent training interventions), and reviewed research findings pertaining to each of these interventions. Toward the end, clinically useful findings were emphasized, important clinical and research issues were discussed, and directions for future treatment outcome studies were provided.
鉴于自闭症谱系障碍(ASD)的各种社会心理治疗方法被提出,以及ASD治疗结果的大量研究积累,本研究旨在回顾目前得到经验支持的ASD儿童的社会心理治疗方法。为了解决这些问题,本研究将重点放在ASD文献中经常观察到的三种类型的社会心理治疗上(行为干预、社会沟通技能干预和父母培训干预),并回顾了与每种干预相关的研究结果。最后,强调了临床有用的发现,讨论了重要的临床和研究问题,并提出了未来治疗结果研究的方向。
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引用次数: 4
Introduction: Neurodevelopmental Disorders 简介:神经发育障碍
Pub Date : 2016-02-01 DOI: 10.7599/HMR.2016.36.1.1
D. Ahn
In this issue, I’m glad to introduce neurodevelopmental disorders. The neurodevelopmental disorders are ‘a group of conditions with onset in the developmental period’, which are firstly introduced in American Psychiatric Association’s fifth edition of Diagnostic and Statistical Manual of Mental Disorders (DSM-5, APA, 2013) [1]. The disorders typically occur in early development and are characterized by developmental deficits that produce impairments of personal, social, academic, or occupational functioning. The deficits of disorders are widely ranged from very specific limitations of learning or communicative skills to global impairments of social interactions or intellectual function. Under the category of the neurodevelopmental disorders, as you know, six diagnostic entities are there. Intellectual disability (intellectual developmental disorder, formerly mental retardation) is characterized by deficits in general mental abilities, such as reasoning, problem solving, planning, abstract thinking, judgement, academic learning, and learning from experience, and also in adaptive functioning in comparison to an individual’s age-, gender-, and socioculturally matched peers. Recently the term ‘mental retardation’ is replaced with the term ‘intellectual disability’ by forensic, educational, and other professionals and public and advocacy groups. The communication disorders include language disorder, speech sound disorder, social (pragmatic) communication disorder, and childhood-onset fluency disorder (stuttering). The first three disorder are characterized by deficits in the development and use of language, speech, and social communication, respectively. Speech is the expressive production of sounds and includes an individual’s articulation, fluency, voice, and resonance quality. Language includes the form, function, and use of a conventional system of symbols (i.e., spoken words, sign language, written words, pictures) in a rule-governed manner for communication. Communication includes any verbal or nonverbal behavior that influences the behavior, ideas, or attitudes of another individual. The core features of language disorder are persistent difficulties in the acquisition and use of language across modalities (i.e., spoken, written, sign language, or other) due to deficits in comprehension or production. Speech sound disorder is characterized by persistent difficulty with speech sound production. Childhood-onset fluency disorder (stuttering) is characterized by disturbances of normal fluency and time patterning of speech, including sound and syllable repetitions, sound prolongation of consonants as well as vowels, broken words, audible or silent blocking, circumlocutions, words produced with an excess of physical tension. Social (pragmatic) communication disorder is a new category in DSM-5, which is characterized by a primary difficulty with language pragmatics, or the social use of language and communication, as manifested by deficits in understan
在这一期,我很高兴介绍神经发育障碍。神经发育障碍是“发育期发病的一组病症”,首次在美国精神病学协会第五版《精神疾病诊断与统计手册》(DSM-5, APA, 2013)中被引入[1]。这些障碍通常发生在发育早期,其特征是发育缺陷,导致个人、社会、学术或职业功能受损。障碍的缺陷范围很广,从非常具体的学习或交流技能的限制到社会交往或智力功能的全面损害。在神经发育障碍的范畴下,如你所知,有六种诊断实体。智力残疾(智力发育障碍,以前称为智力迟钝)的特征是一般智力能力的缺陷,如推理、解决问题、计划、抽象思维、判断、学术学习和从经验中学习,以及与年龄、性别和社会文化匹配的同龄人相比的适应功能。最近,“智力迟钝”一词被法医、教育和其他专业人士以及公众和倡导团体用“智力残疾”一词取代。沟通障碍包括语言障碍、语音障碍、社会(语用)沟通障碍和儿童时期的流利性障碍(口吃)。前三种障碍的特征分别是语言、言语和社会沟通的发展和使用缺陷。言语是声音的表达,包括个人的发音、流利度、声音和共鸣质量。语言包括形式、功能和使用传统的符号系统(即口语、手语、书面文字、图片),以一种规则管理的方式进行交流。沟通包括任何影响他人行为、想法或态度的言语或非言语行为。语言障碍的核心特征是由于理解或生产方面的缺陷,在跨形式(即口语、书面语、手语或其他)的语言习得和使用方面持续存在困难。语音障碍的特征是语音产生持续困难。儿童期发作的流利性障碍(口吃)的特征是正常的流利性和语言时间模式的紊乱,包括声音和音节的重复,辅音和元音的发音延长,破碎的单词,可听或无声的阻塞,绕口令,说话时身体过度紧张。社会(语用)交际障碍是DSM-5中的一个新类别,其特征是语言语用或语言的社会使用和交际的主要困难,表现为理解和遵循言语和非言语交际的社会规则的缺陷,改变语言以适应语境或听者的需要,遵循对话和讲故事的规则。自闭症谱系障碍(Autism spectrum disorder, ASD)是DSM-5中新增的一个类别,取代了dsm - iv中的广泛性发育障碍(pervasive developmental disorders, pdd)。DSM-5引入了由维度衍生的频谱概念。基于之前在DSM-IV中单独列出的PDD标题下的三种疾病的理解是更好的控制
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引用次数: 0
Early Detection and Intervention of Autism Spectrum Disorder 自闭症谱系障碍的早期发现与干预
Pub Date : 2016-02-01 DOI: 10.7599/HMR.2016.36.1.4
H. Yoo
Autism spectrum disorder (ASD) is a neurodevelopmental disorder typically identified in early toddlerhood. Both retrospective and prospective follow up studies of high risk infants reveal early risk signs of ASD at 12-24 months of age. The most frequently replicated early signs of ASD are atypical visual tracking and coordination, lack of social reciprocity, abnor- mal social communication and unusual patterns of manipulating objects, atypical sensory exploration, expressed as uncoordinated eye contact, unresponsiveness to naming, lack of social smile, delayed development of nonverbal communication and joint attention, less sharing interest, and unusually repetitive use of objects. Early intervention, before 2 years of age, appears to change the underlying developmental trajectories of the brain in indi- viduals with ASD. In this review, the early risk signs of ASD in infancy and toddlerhood, along with early intervention and their implications, are discussed.
自闭症谱系障碍(ASD)是一种典型的幼儿期神经发育障碍。对高危婴儿的回顾性和前瞻性随访研究均显示,在12-24个月大时出现ASD的早期危险体征。最常见的ASD早期症状是非典型的视觉跟踪和协调,缺乏社会互惠,异常的社会沟通和不寻常的操作物体模式,非典型的感官探索,表现为不协调的眼神交流,对命名没有反应,缺乏社交微笑,非语言沟通和共同注意发展迟缓,缺乏共享兴趣,以及异常重复使用物体。早期干预,在2岁之前,似乎可以改变ASD患者大脑的潜在发育轨迹。本文就婴幼儿期ASD的早期危险体征、早期干预及其意义进行综述。
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引用次数: 8
期刊
Hanyang Medical Reviews
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