Background
Lateral lumbar interbody fusion (LLIF) and single position prone lateral (PTP) approaches represent significant advances in minimally invasive spine surgery, yet comprehensive comparative analysis of their research trajectories remains limited.
Purpose
This bibliometric analysis aims to comprehensively compare the scientific landscapes surrounding LLIF and PTP approaches by examining publication trends, citation patterns, authorship networks, and thematic evolution.
Methods
We systematically searched Scopus, PubMed and Google Scholar from inception through September 2025 for articles addressing LLIF and single position prone lateral approaches. Bibliometrix package in R was used to complete the bibliometric analysis. We included the following parameters: publication output, citation metrics, journal distribution, author productivity, international collaboration networks, keyword co-occurrence, and thematic mapping in the analysis.
Results
We identified 823 LLIF publications and 107 single position prone lateral publications. LLIF accounted for 20,707 total citations with an h-index of 70 and a mean of 31.93 citations per document, whereas PTP accumulated 915 citations with an h-index of 17 and a mean of 8.44 citations per document. Although LLIF has a larger volume of publications, PTP has progressed more rapidly, showing annual growth rates of 44% compared with 30% for LLIF during comparable developmental periods. The United States contributed 45.6% of LLIF and 71.8% of PTP publications, with LLIF research spanning 42 countries and PTP 16 countries. Core research themes for both techniques evolved from technical descriptions to comparative effectiveness studies, and the substantial overlap in authors and institutions indicates complementary rather than competitive research trajectories.
Conclusions
LLIF represents a mature surgical approach with a strong evidence base while PTP demonstrates accelerating research interest, with growth trajectories exceeding those of LLIF during comparable developmental stages. Based on current publication trends and thematic evolution, future research on PTP should prioritize rigorous comparative studies, long-term outcome evaluations, cost-effectiveness analyses, and patient-centered outcome research to strengthen the evidence base and guide clinical adoption.
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