{"title":"Efficacy and Safety of Traditional Chinese Medicine Combined with Western Medicine for the Treatment of COVID-19: A Systematic Review and Meta-analysis","authors":"","doi":"10.4103/hm.hm_9_24","DOIUrl":"https://doi.org/10.4103/hm.hm_9_24","url":null,"abstract":"","PeriodicalId":34653,"journal":{"name":"Heart and Mind","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141015193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Empirical Findings on Associations between Anxiety, Depression, and Congenital Heart Disease in Adults – A Systematic Review and Meta-analysis","authors":"","doi":"10.4103/hm.hm_8_24","DOIUrl":"https://doi.org/10.4103/hm.hm_8_24","url":null,"abstract":"","PeriodicalId":34653,"journal":{"name":"Heart and Mind","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141015603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Role of Implantable Loop Recorder in Patients with Cryptogenic Stroke: A Systematic Review and Meta-analysis","authors":"","doi":"10.4103/hm.hm_7_24","DOIUrl":"https://doi.org/10.4103/hm.hm_7_24","url":null,"abstract":"","PeriodicalId":34653,"journal":{"name":"Heart and Mind","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141015850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative Utility of Biofeedback Parameters in Predicting Perceived Relaxation","authors":"","doi":"10.4103/hm.hm_6_24","DOIUrl":"https://doi.org/10.4103/hm.hm_6_24","url":null,"abstract":"","PeriodicalId":34653,"journal":{"name":"Heart and Mind","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140664504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-10DOI: 10.4103/hm.hm-d-23-00066
Ni He, Hanxiu Liu, Jing Liu, Xiqiang Wang, Junkui Wang, Hengwei Xu, Zhongwei Liu
Mood disorders, encompassing major depressive disorder and bipolar disorder, present complex etiologies involving neuroanatomical, neurotransmitter, and inflammatory mechanisms. Recent research explores the role of platelets, traditionally associated with hemostasis, in the pathophysiology of mood disorders. We examine neuroanatomical insights, neurotransmitter dysregulation, and the link between inflammation and mood disorders, emphasizing the complex nature of mood disturbances. Emerging evidence of altered platelet function in mood disorders and the therapeutic potential of antiplatelet agents and serotonin reuptake inhibitors are discussed. While personalized medicine holds promise, further research is needed to fully comprehend this evolving field. This review offers comprehensive insights into mood disorder diagnosis, intervention, and pathophysiology. In this review, a comprehensive literature search was conducted using databases such as PubMed, Scopus, and Web of Science. The search focused on articles published from 2000 to 2023, using keywords like “platelet function,” “mood disorders,” and “neurotransmitter dysregulation.” We included studies that specifically investigated the role of platelets in mood disorders, encompassing various study designs and population demographics.
情绪障碍包括重度抑郁障碍和双相情感障碍，病因复杂，涉及神经解剖、神经递质和炎症机制。最近的研究探索了传统上与止血相关的血小板在情绪障碍病理生理学中的作用。我们研究了神经解剖学见解、神经递质失调以及炎症与情绪障碍之间的联系，强调了情绪障碍的复杂性。我们还讨论了情绪障碍中血小板功能改变的新证据，以及抗血小板药物和血清素再摄取抑制剂的治疗潜力。虽然个性化医疗前景广阔，但要全面了解这一不断发展的领域，还需要进一步的研究。本综述对情绪障碍的诊断、干预和病理生理学提供了全面的见解。本综述使用 PubMed、Scopus 和 Web of Science 等数据库进行了全面的文献检索。检索的重点是 2000 年至 2023 年发表的文章，使用的关键词包括 "血小板功能"、"情绪障碍 "和 "神经递质失调"。我们收录了专门研究血小板在情绪障碍中作用的研究，包括各种研究设计和人口统计数据。
{"title":"Platelet Function in Mood Disorders: Interplay, Clinical Implications, and Future Perspectives – A Narrative Review","authors":"Ni He, Hanxiu Liu, Jing Liu, Xiqiang Wang, Junkui Wang, Hengwei Xu, Zhongwei Liu","doi":"10.4103/hm.hm-d-23-00066","DOIUrl":"https://doi.org/10.4103/hm.hm-d-23-00066","url":null,"abstract":"\u0000 Mood disorders, encompassing major depressive disorder and bipolar disorder, present complex etiologies involving neuroanatomical, neurotransmitter, and inflammatory mechanisms. Recent research explores the role of platelets, traditionally associated with hemostasis, in the pathophysiology of mood disorders. We examine neuroanatomical insights, neurotransmitter dysregulation, and the link between inflammation and mood disorders, emphasizing the complex nature of mood disturbances. Emerging evidence of altered platelet function in mood disorders and the therapeutic potential of antiplatelet agents and serotonin reuptake inhibitors are discussed. While personalized medicine holds promise, further research is needed to fully comprehend this evolving field. This review offers comprehensive insights into mood disorder diagnosis, intervention, and pathophysiology. In this review, a comprehensive literature search was conducted using databases such as PubMed, Scopus, and Web of Science. The search focused on articles published from 2000 to 2023, using keywords like “platelet function,” “mood disorders,” and “neurotransmitter dysregulation.” We included studies that specifically investigated the role of platelets in mood disorders, encompassing various study designs and population demographics.","PeriodicalId":34653,"journal":{"name":"Heart and Mind","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140720104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-15DOI: 10.4103/hm.hm-d-23-00047
Yewei Pan, Zishan Zhang, Xuerui Tan, Jinxiu Zhu
Brain-derived neurotrophic factor (BDNF) as a biomarker of depressive symptoms manifests a novel role in the cardiovascular system. This study aims to indicate the association of BDNF levels between depressive symptoms and the cardiovascular prognosis in coronary heart disease (CHD) patients. Participants were recruited from hospitalized CHD patients between November 18, 2020 and November 26, 2021, in the First Affiliated Hospital of Shantou University Medical College. Serum BDNF levels were measured by the enzyme-linked immunosorbent assays. Depressive symptom was evaluated using Patient Health Questionnaire (PHQ-9). The cardiovascular events were the endpoint outcomes across the 12-month follow-up. Kaplan–Meier curves and Cox proportional hazards regression models were used to investigate the relationship of serum BDNF levels between depressive symptom and prognosis. A total of 102 CHD patients (60.6 ± 10.4 year, 76% male) were enrolled. Based on the median serum BDNF levels, the participants were grouped into those “low BDNF (≤0.65 ng/mL)” versus “high BDNF (≥0.65 ng/mL).” CHD patients with low BDNF levels had a higher prevalence of depressive symptoms (PHQ–9 ≥10) compared with high BDNF levels. Within a median 540 days of follow-up, low serum BDNF increased the risk of cardiovascular events (adjusted hazard ratio = 3.26; 95% confidence interval = 1.18–9.02, P = 0.02) after adjustment for confounding factors. CHD patients with low serum BDNF levels were significantly associated with an increased risk of cardiovascular events, independently of depressive symptoms.
{"title":"Independent Impact of Brain-Derived Neurotrophic Factor on Cardiovascular Prognosis in Coronary Heart Disease Patients: A Prospective Cohort Study","authors":"Yewei Pan, Zishan Zhang, Xuerui Tan, Jinxiu Zhu","doi":"10.4103/hm.hm-d-23-00047","DOIUrl":"https://doi.org/10.4103/hm.hm-d-23-00047","url":null,"abstract":"\u0000 \u0000 \u0000 Brain-derived neurotrophic factor (BDNF) as a biomarker of depressive symptoms manifests a novel role in the cardiovascular system. This study aims to indicate the association of BDNF levels between depressive symptoms and the cardiovascular prognosis in coronary heart disease (CHD) patients.\u0000 \u0000 \u0000 \u0000 Participants were recruited from hospitalized CHD patients between November 18, 2020 and November 26, 2021, in the First Affiliated Hospital of Shantou University Medical College. Serum BDNF levels were measured by the enzyme-linked immunosorbent assays. Depressive symptom was evaluated using Patient Health Questionnaire (PHQ-9). The cardiovascular events were the endpoint outcomes across the 12-month follow-up. Kaplan–Meier curves and Cox proportional hazards regression models were used to investigate the relationship of serum BDNF levels between depressive symptom and prognosis.\u0000 \u0000 \u0000 \u0000 A total of 102 CHD patients (60.6 ± 10.4 year, 76% male) were enrolled. Based on the median serum BDNF levels, the participants were grouped into those “low BDNF (≤0.65 ng/mL)” versus “high BDNF (≥0.65 ng/mL).” CHD patients with low BDNF levels had a higher prevalence of depressive symptoms (PHQ–9 ≥10) compared with high BDNF levels. Within a median 540 days of follow-up, low serum BDNF increased the risk of cardiovascular events (adjusted hazard ratio = 3.26; 95% confidence interval = 1.18–9.02, P = 0.02) after adjustment for confounding factors.\u0000 \u0000 \u0000 \u0000 CHD patients with low serum BDNF levels were significantly associated with an increased risk of cardiovascular events, independently of depressive symptoms.\u0000","PeriodicalId":34653,"journal":{"name":"Heart and Mind","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140241162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.4103/hm.hm-d-23-00040
Joana Brito, Daniel Caldeira, Catarina Gregório, Rui Plácido, Fausto J. Pinto
COVID-19 infection is associated with significant complications affecting multiple organs other than the respiratory system. In fact, there seems to be a bidirectional relation between cardiovascular disease and viral infection, as patients with prior cardiac comorbidities are at a higher risk of adverse events during infection, and COVID-19 infection seems to exponentiate the risk of acute and long-term cardiac events. In this review, the authors will discuss the acute and long-term impact of COVID-19 infection in arterial hypertension, heart failure, angina pectoris, myocardial infarction, and atrial fibrillation.
{"title":"Arterial Hypertension, Heart Failure, Angina Pectoris, Myocardial Infarction, and Atrial Fibrillation after COVID-19: A Narrative Review","authors":"Joana Brito, Daniel Caldeira, Catarina Gregório, Rui Plácido, Fausto J. Pinto","doi":"10.4103/hm.hm-d-23-00040","DOIUrl":"https://doi.org/10.4103/hm.hm-d-23-00040","url":null,"abstract":"\u0000 COVID-19 infection is associated with significant complications affecting multiple organs other than the respiratory system. In fact, there seems to be a bidirectional relation between cardiovascular disease and viral infection, as patients with prior cardiac comorbidities are at a higher risk of adverse events during infection, and COVID-19 infection seems to exponentiate the risk of acute and long-term cardiac events. In this review, the authors will discuss the acute and long-term impact of COVID-19 infection in arterial hypertension, heart failure, angina pectoris, myocardial infarction, and atrial fibrillation.","PeriodicalId":34653,"journal":{"name":"Heart and Mind","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139684824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-25DOI: 10.4103/hm.hm-d-23-00050
J. Rissardo, A. Caprara
{"title":"Impact of Age on the Outcomes of Atrial Fibrillation-Related Stroke","authors":"J. Rissardo, A. Caprara","doi":"10.4103/hm.hm-d-23-00050","DOIUrl":"https://doi.org/10.4103/hm.hm-d-23-00050","url":null,"abstract":"","PeriodicalId":34653,"journal":{"name":"Heart and Mind","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139596912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-24DOI: 10.4103/hm.hm-d-23-00056
Łukasz A. Małek
Athletes undergo mandatory or voluntary cardiac testing, which may include 24-h ambulatory electrocardiogram monitoring. This study can on occasion disclose nocturnal pauses in otherwise asymptomatic healthy individuals. In some athletes, particularly those engaging in endurance or mixed sports, the pauses can be longer than 2–3 s and/or be caused by sinus arrest high-degree atrioventricular block not typical for physiological adaptation to exercise. The manuscript discusses the physiology and potential pathologies behind long nocturnal pauses in athletes. Several management strategies are proposed including emerging treatment techniques such as cardioneuroablation.
{"title":"How Long is Too Long? Asymptomatic Nocturnal Pauses in Athletes: A Narrative Review","authors":"Łukasz A. Małek","doi":"10.4103/hm.hm-d-23-00056","DOIUrl":"https://doi.org/10.4103/hm.hm-d-23-00056","url":null,"abstract":"\u0000 Athletes undergo mandatory or voluntary cardiac testing, which may include 24-h ambulatory electrocardiogram monitoring. This study can on occasion disclose nocturnal pauses in otherwise asymptomatic healthy individuals. In some athletes, particularly those engaging in endurance or mixed sports, the pauses can be longer than 2–3 s and/or be caused by sinus arrest high-degree atrioventricular block not typical for physiological adaptation to exercise. The manuscript discusses the physiology and potential pathologies behind long nocturnal pauses in athletes. Several management strategies are proposed including emerging treatment techniques such as cardioneuroablation.","PeriodicalId":34653,"journal":{"name":"Heart and Mind","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139600772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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