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Psychedelics, embodiment, and intersubjectivity 致幻剂、化身和主体间性
IF 4.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2023-08-14 DOI: 10.1556/2054.2023.00257
Kai River Blevins
Research into the social aspects of set and setting have demonstrated that race is a significant factor in psychedelic experiences for racially marginalized populations. Yet, many studies of psychedelic-induced experiences continue to proceed without collecting data on or considering the influence of race or other social categories. These approaches abstract subjectivity from its embodied and historical conditions, isolating consciousness in ways that do not accord with lived experience.This article draws on critical phenomenology, anthropology, and treatments of race in the field of psychedelic studies to outline how social categories mediate subjective experience in historically specific ways through the framework of embodiment.I argue that consciousness is fundamentally intersubjective, including during psychedelic-induced experiences. Intersubjectivity is an existential condition that makes possible meaning, communication, and socialization, processes which rely on and are perpetually (re)enacted through social categories. Therefore, studies of psychedelic-induced experiences must account for the foundational role that social categories play in constituting such embodied experiences and their effects.This approach makes embodied differences matter to the study of psychedelic-induced experiences, opening new avenues of inquiry that foreground identity, power, and context in both clinical and naturalistic research.
对set和setting的社会方面的研究表明,种族是种族边缘化人群迷幻体验的重要因素。然而,许多关于迷幻药诱发体验的研究继续进行,没有收集数据或考虑种族或其他社会类别的影响。这些方法将主体性从其具体的和历史的条件中抽象出来,以不符合生活经验的方式孤立意识。本文借鉴了迷幻研究领域的批判现象学、人类学和种族治疗方法,概述了社会类别如何通过具体化的框架以历史上特定的方式调解主观体验。我认为意识基本上是主体间性的,包括在迷幻药诱导的体验中。主体间性是一种存在条件,它使意义、交流和社会化成为可能,这些过程依赖于社会类别,并通过社会类别不断(重新)制定。因此,对迷幻诱导体验的研究必须考虑到社会类别在构成这种具体化体验及其影响中所起的基础作用。这种方法使得具身差异对迷幻诱导体验的研究很重要,在临床和自然主义研究中开辟了新的研究途径,前景身份,权力和背景。
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引用次数: 0
In naturalistic psychedelic use, group use is common and acceptable 在自然主义的迷幻药使用中,集体使用是常见的,也是可以接受的
IF 4.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2023-06-19 DOI: 10.1556/2054.2023.00261
K. Byrne, S. Lindsay, Nicholas M. Baker, C. Schmutz, Ben Lewis
Most modern modalities of psychedelic-assisted psychotherapy (PAP) aim to minimize harm and maximize support by utilizing close, formalized supervision for a single participant per session. However, these substances are used naturalistically in a wide variety of settings. Our goal was to evaluate the perceived benefits and harms of naturalistic psychedelic use in diverse settings, with and without guidance/supervision.An anonymous survey was distributed over Internet forums to solicit responses from English-speaking adults, with questions regarding the setting and perceived mental health-related outcomes of classic psychedelics. Data were analyzed to compare effects of group versus solo setting on perceived outcomes.For the goal of improving mental health, use in a solo setting was more common than in a group setting (COR 0.37 (0.20–0.68), p = 0.03) and was associated with more subjective symptom improvement (COR 0.22 (0.11–0.42), p = 0.0002). However, there was no significant difference in perceived overall mental health benefit between use in group and solo settings (p = 1). Subjective negative outcomes on mental health were rare and not associated more so with psychedelic use in any particular setting. A majority of naturalistic psychedelic use took place in an informal setting, with no significant difference between solo or group users (95% vs 91%, p = 0.3).Naturalistic psychedelic users are as likely to report an overall positive outcome and no more likely to report adverse events in group settings than in solo settings. This supports further research into PAP in group settings.
大多数现代的迷幻辅助心理治疗(PAP)模式旨在通过在每次治疗中对单个参与者进行密切、正式的监督,将伤害降至最低,并最大限度地提供支持。然而,这些物质被自然地用于各种各样的环境中。我们的目标是在有指导/监督的情况下,评估在不同环境中使用自然主义迷幻药的益处和危害。通过互联网论坛发布了一项匿名调查,征求讲英语的成年人的回复,询问有关经典迷幻药环境和感知的心理健康结果的问题。对数据进行分析,比较小组和单独设置对感知结果的影响。为了改善心理健康,在单独环境中使用比在团体环境中更常见(COR 0.37(0.20–0.68),p=0.003),并且与更主观的症状改善有关(COR 0.22(0.11–0.42),p=0.0002)。然而,在团体和单独环境中的使用在感知的整体心理健康益处方面没有显著差异(p=1)。心理健康方面的主观负面结果是罕见的,在任何特定环境中使用迷幻药都没有更大的关联。大多数自然主义迷幻药的使用发生在非正式环境中,单独或集体使用者之间没有显著差异(95%对91%,p=0.03)。自然主义迷幻剂使用者在集体环境中报告总体积极结果的可能性与单独环境中报告不良事件的可能性一样大。这有助于进一步研究群体环境中的PAP。
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引用次数: 0
Philosophy and psychedelics: Frameworks for exceptional experience 哲学与迷幻:特殊体验的框架
IF 4.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2023-06-19 DOI: 10.1556/2054.2023.00283
T. Dowie, Julien Tempone-Wiltshire
The intersection between philosophy and psychedelics is explored in the book “Philosophy and Psychedelics: Frameworks for Exceptional Experience”. The authors aim to develop a dialogue between the two disciplines and explore the various frameworks for understanding exceptional experiences that psychedelics have afforded human beings. The book delves into foundational, ontological, and epistemological questions, including the hard problem of consciousness, the metaphysical understanding of the self, and the aesthetic meaning of the sublime in psychedelic experience. The book provides valuable exploration of questions concerning prevailing metaphysical frameworks, epistemic belief structures, and modes of inquiry, and the effort made by the authors to bring into dialogue multiple dialectics and practices, perspectives and methods is commendable.
《哲学与迷幻:特殊体验的框架》一书探讨了哲学与迷幻之间的交集。作者旨在发展两个学科之间的对话,并探索理解迷幻药给人类带来的特殊体验的各种框架。这本书深入研究了基础,本体论和认识论问题,包括意识的难题,对自我的形而上学理解,以及迷幻体验中崇高的美学意义。本书对流行的形而上学框架、认知信仰结构和探究模式等问题进行了有价值的探索,作者将多种辩证法和实践、观点和方法带入对话的努力值得称赞。
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引用次数: 7
The DEA report on ayahuasca risks: “Science” in service of prohibition? 缉毒局关于阿亚瓦斯卡风险的报告:为禁令服务的“科学”?
IF 4.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2023-06-09 DOI: 10.1556/2054.2023.00279
B. Labate, A. Ermakova, Jordan Sloshower, N. Galvão-Coelho, Fernanda Palhano-Fontes, Henrique Fernandes Antunes, Glauber Loures de Assis, Clancy Cavnar, D. D. de Araujo, S. Ribeiro
On February 2023, the Drug Enforcement Administration (DEA) released a document to the legal team representing the Church of the Eagle and the Condor (“CEC”). This disclosure came two years after the church, in conjunction with Chacruna Institute, submitted two FOIA requests to the DEA and the Department of Justice requesting all records pertaining to ayahuasca. This report, titled “Ayahuasca: Risks to Public Health and Safety,” was issued in July 2020. In the present article, we challenge a number of claims made in the DEA report and highlight significant factual omissions, theoretical biases, and misinterpretations of existing data. We will demonstrate that the DEA report severely downplays the safety profile and therapeutic potential of ayahuasca and overemphasizes the risks. It also fails to include current research on ayahuasca demonstrating its potential benefits.
2023年2月,缉毒局向代表鹰与秃鹰教会(“CEC”)的法律团队发布了一份文件。两年前,教会与查克鲁纳研究所一起向缉毒局和司法部提交了两份《信息自由法》请求,要求提供与阿亚瓦斯卡有关的所有记录。这份题为《阿亚瓦斯卡:公共健康和安全风险》的报告于2020年7月发布。在本文中,我们对缉毒局报告中的一些说法提出了质疑,并强调了对现有数据的重大事实遗漏、理论偏见和误解。我们将证明,缉毒局的报告严重淡化了阿亚瓦斯卡的安全性和治疗潜力,并过度强调了风险。它也没有包括目前对阿亚瓦斯卡的研究,证明其潜在的好处。
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引用次数: 0
Ten years of Psychedemia — and the future 精神病的十年——以及未来
IF 4.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2023-05-24 DOI: 10.1556/2054.2023.00272
Emma Stamm
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引用次数: 0
Lifetime classic psychedelic use is associated with greater psychological distress in unemployed job seekers 终身使用经典迷幻药与失业求职者更大的心理困扰有关
IF 4.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2023-05-16 DOI: 10.1556/2054.2023.00246
Benjamin A. Korman
Despite recent research linking lifetime classic psychedelic use to positive mental health outcomes, little work has explored the role played by classic psychedelics in healthy users' ability to cope with ordinary, yet stressful, life situations.This study begins to fill this gap by exploring whether lifetime classic psychedelic use is associated with attenuated or exacerbated psychological distress in unemployed job seekers.Drawing on openly-available data from the National Survey on Drug Use and Health (2013–2019) on 208,136 adults in the United States, this study tests whether lifetime classic psychedelic use interacts with employment status to predict differences in respondents' psychological distress experienced in the last 30 days.After adjusting for sociodemographics, health factors, and other substance use, unemployed job seekers with lifetime classic psychedelic use are found to report greater psychological distress relative to unemployed job seekers without lifetime psychedelic use. No differences in psychological distress based on lifetime classic psychedelic use were found in employed individuals.This study suggests that lifetime classic psychedelic use (of indoleamines specifically) may exacerbate stressful phases of life and provides context to previous studies linking lifetime classic psychedelic use to predominantly positive mental health outcomes in healthy populations.This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors. Furthermore, the author declares that there is no conflict of interest.
尽管最近的研究将终生使用经典迷幻药与积极的心理健康结果联系起来,但很少有研究探讨经典迷幻剂在健康使用者应对普通但有压力的生活情况的能力中所起的作用。这项研究开始填补这一空白,探索终身使用经典迷幻药是否与失业求职者的心理痛苦减轻或加剧有关。根据美国国家药物使用与健康调查(2013-2019)对208136名成年人的公开数据,本研究测试了终生经典迷幻药的使用是否与就业状况相互作用,以预测受访者在过去30天内经历的心理困扰的差异。在对社会人口统计学、健康因素和其他物质使用进行调整后,发现终身使用经典迷幻药的失业求职者报告的心理困扰比终身未使用迷幻药求职者更大。在就业个体中,基于终生经典迷幻药使用的心理困扰没有发现差异。这项研究表明,终生经典迷幻药的使用(特别是吲哚胺)可能会加剧生活中的压力阶段,并为之前的研究提供了背景,这些研究将终生经典迷幻剂的使用与健康人群中主要积极的心理健康结果联系起来。这项研究没有得到任何公共、商业或非营利部门资助机构的具体资助。此外,提交人声称不存在利益冲突。
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引用次数: 0
Entheogens and spiritual seeking: The quest for self-transcendence, psychological well-being, and psychospiritual growth 热情与精神追求:对自我超越、心理健康和精神成长的追求
IF 4.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2023-04-21 DOI: 10.1556/2054.2023.00263
K. O. St. Arnaud, D. Sharpe
Although numerous cultures have used psychoactive substances for spiritual, or entheogenic, purposes, little is known about contemporary entheogenic spirituality, particularly outside of the few traditions that retain sacramental drug use practices.To better conceptualize contemporary patterns of entheogenic drug use, an international, online study of entheogenic drug users was conducted (n = 684). Hierarchical regression analysis was used to explore entheogenic drug use in relation to measures of spiritual seeking (importance of spirituality in life, mediation practice, openness to experience), self-transcendent experiences (awe-proneness, mystical experiences), psychological well-being (psychological distress, subjective and eudaimonic well-being), and psychospiritual development (quiet ego, self-transcendence/wisdom, and spiritual development). ANOVA was used to compare entheogenic drug users with non-entheogenic drug users and non-drug users to assess differences across these psychospiritual variables.Of the 12 drug categories assessed, the classic psychedelics were most commonly used as entheogens. Entheogenic classic psychedelic use was associated with all of the assessed psychospiritual variables; entheogenic classic psychedelic users showed higher levels of spiritual seeking, self-transcendence, psychological well-being, and psychospiritual development compared to non-entheogenic classic psychedelic users and non-users.Entheogenic spirituality may be conceptualized as a practice of spiritual seeking or implicit mysticism–the quest for self-transcendence and personal growth.
尽管许多文化都将精神活性物质用于精神或致幻目的,但对当代致幻精神知之甚少,尤其是在少数保留圣礼药物使用习俗的传统之外。为了更好地概念化当代致幻药物使用模式,对致幻药物使用者进行了一项国际在线研究(n=684)。采用层次回归分析法探讨了致幻药物的使用与精神寻求(精神在生活中的重要性、中介实践、对体验的开放性)、自我超越体验(敬畏倾向、神秘体验)、心理幸福感(心理困扰、主观幸福感和幸福感)、,精神心理发展(安静的自我、自我超越/智慧和精神发展)。方差分析用于比较致幻性药物使用者、非致幻性毒品使用者和非毒品使用者,以评估这些精神心理变量之间的差异。在评估的12种药物类别中,经典的迷幻药最常被用作兴奋剂。致热的经典迷幻药使用与所有评估的精神心理变量有关;与非致幻性经典迷幻药使用者和非致幻型经典迷幻剂使用者相比,致幻性古典迷幻药用户表现出更高的精神追求、自我超越、心理健康和精神心理发展水平。热情精神可以被概念化为一种精神追求或隐含神秘主义的实践——对自我超越和个人成长的追求。
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引用次数: 0
View, meditation, action: A Tibetan framework to inform psychedelic-assisted therapy 观点、冥想、行动:一个为迷幻辅助治疗提供信息的西藏框架
IF 4.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2023-03-28 DOI: 10.1556/2054.2023.00255
Colin H. Simonds
Whether occasioned through careful, consistent meditative practice or through quicker means like the ritual ingestion of psilocybin or ayahuasca, global contemplative practices have established effective systems of implementing, directing, and integrating the very kinds of non-ordinary experiences central to psychedelic use. However, contemplative traditions are largely absent from the present discourse on psychedelic therapy. This paper addresses this gap and offers a novel analysis of psychedelic-assisted therapy through the lens of the Tibetan Buddhist contemplative tradition. It first establishes a baseline for comparing the non-ordinary experience occasioned by Tibetan Buddhist meditation and the psychedelic experience by referencing the phenomenological literature of both. It then articulates the Tibetan contemplative framework of view, meditation, action (Tib. lta sgom spyod gsum) as the way Tibetan Buddhism directs its non-ordinary meditative experience towards its desired ends and suggests how this framework may be applied to psychedelic-assisted therapy. Finally, this paper uses this Tibetan Buddhist lens of analysis to compare and assess two protocols for psychedelic-assisted therapy and to make recommendations for future clinical protocols. Given the phenomenological similarity of Tibetan Buddhist meditative experience and the psychedelic experience, this article suggests that a more intensive preparatory session where maladaptive conceptual narratives are worked through and beneficial ones are introduced, repeated dosing sessions, and a more directed psychedelic experience may increase the efficacy of psychedelic-assisted therapy. It thus argues that the insights of the Tibetan framework of view, meditation, action can improve future protocols and allow for psychedelic-assisted therapy to be of even greater benefit.
无论是通过谨慎、持续的冥想练习,还是通过仪式性摄入裸盖菇素或阿亚瓦斯卡等更快的方式,全球冥想练习都建立了有效的系统来实施、指导和整合迷幻药使用的核心非普通体验。然而,在目前关于迷幻疗法的讨论中,沉思传统在很大程度上是缺失的。本文解决了这一差距,并通过藏传佛教冥想传统的视角对迷幻辅助治疗进行了新颖的分析。它首先通过参考藏传佛教冥想和迷幻体验的现象学文献,为比较这两种体验建立了一个基线。然后,它阐述了西藏的冥想、冥想和行动框架(Tib.lta-sgom spyod-gsum),作为藏传佛教将其非普通冥想体验引导到其期望目的的方式,并建议如何将该框架应用于迷幻辅助治疗。最后,本文利用藏传佛教的分析视角,对两种迷幻辅助治疗方案进行了比较和评估,并对未来的临床方案提出了建议。鉴于藏传佛教冥想体验和迷幻体验在现象学上的相似性,本文建议,在更密集的准备会议上,通过不适应的概念叙事并引入有益的叙事,重复给药会议,以及更直接的迷幻体验,可以提高迷幻辅助治疗的疗效。因此,它认为,藏人的观点、冥想和行动框架的见解可以改善未来的方案,并使迷幻辅助治疗具有更大的益处。
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引用次数: 0
Association between mystical-type experiences under psychedelics and improvements in well-being or mental health – A comprehensive review of the evidence 迷幻药下的神秘体验与幸福感或心理健康改善之间的联系——证据的全面综述
IF 4.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2023-03-03 DOI: 10.1556/2054.2023.00243
Samuli Kangaslampi
Ingestion or administration of classic psychedelics is sometimes associated with improvements in well-being or mental health. Acute mystical-type experiences that psychedelics occasion have been suggested to be related to such improvements. Meanwhile, other features of the psychedelic experience, such as psychological insights and emotional breakthroughs, are also increasingly being studied. This review aimed to collect and assess the available evidence for mystical-type experiences under psychedelics associating with medium-to-long term improvements in well-being or mental health, on their own and as compared with other features of the acute experience.I conducted a pre-registered, comprehensive review of existing empirical studies on the topic, based on a systematic search of the literature.Forty-four eligible studies were found, with most reporting positive associations between mystical-type experiences and improvements in well-being or mental health. The current level of evidence appeared stronger among healthy people, in cross-sectional studies, and for links with positive changes in general well-being and life satisfaction, attitudes and behavior, and anxiety, than for depression or other aspects of well-being and mental health. A few studies suggested that psychological insights and emotional breakthroughs may be as or more closely associated with positive changes than mystical-type experiences.Despite their significant limitations, the identified studies suggest that mystical-type experiences under psychedelics are associated with improvements in some areas of well-being. However, psychological insights and emotional breakthroughs might be at least as important and should also be measured in future studies.
摄入或服用经典致幻剂有时与改善幸福感或精神健康有关。迷幻药引起的急性神秘型体验被认为与这种改善有关。与此同时,迷幻体验的其他特征,如心理洞察力和情感突破,也越来越多地被研究。本综述旨在收集和评估迷幻药下的神秘型体验与幸福感或心理健康的中长期改善相关的现有证据,这些体验本身以及与急性体验的其他特征相比较。在系统检索文献的基础上,我对该主题的现有实证研究进行了预先注册的全面回顾。发现了44项符合条件的研究,其中大多数报告了神秘类型的体验与幸福感或心理健康的改善之间的积极联系。在横断面研究中,目前的证据水平在健康人群中似乎更强,并且与总体福祉和生活满意度,态度和行为以及焦虑的积极变化有关,而不是抑郁或福祉和心理健康的其他方面。一些研究表明,与神秘的体验相比,心理上的洞察力和情感上的突破可能与积极的变化有着同样或更密切的联系。尽管存在显著的局限性,但已确定的研究表明,迷幻药下的神秘体验与某些领域的幸福感改善有关。然而,心理上的洞察力和情感上的突破可能至少同样重要,也应该在未来的研究中加以衡量。
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引用次数: 3
The impacts of the drug war on Indigenous Peoples in Latin America: An overview 毒品战争对拉丁美洲土著人民的影响:概述
IF 4.5 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2023-03-03 DOI: 10.1556/2054.2023.00239
B. Labate, Thiago Rodrigues
This paper aims at presenting an overview of the historic and current features concerning the relationship among original peoples, psychoactive drugs, and various forms of anti-drug practices in Latin America. The current expansion of extractivist capitalism in Latin America overlaps with Indigenous peoples' traditional lands, provoking new forms of violence and confrontation. The War on Drugs is being used as a justification to militarize these lands and to criminalize Indigenous populations. Thus, neo-extractivist initiatives in Latin America provoke renewed clashes between Indigenous peoples' interests and local and global elites' purposes. We seek to raise awareness about the relationship between the drug war and Indigenous people's human rights violations as an alert and an invitation for social scientists to engage in theoretical and empirical research on this issue.
本文旨在概述拉丁美洲原住民,精神药物和各种形式的禁毒实践之间关系的历史和当前特征。目前在拉丁美洲,采掘资本主义的扩张与土著人民的传统土地重叠,引发了新形式的暴力和对抗。禁毒战争正被用来作为将这些土地军事化和将土著居民定为犯罪的理由。因此,拉丁美洲的新采掘主义倡议在土著人民的利益与当地和全球精英的目的之间引发了新的冲突。我们力求提高对毒品战争与土著人民侵犯人权之间关系的认识,以此作为一种警告,并邀请社会科学家对这一问题进行理论和实证研究。
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引用次数: 0
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Journal of Psychedelic Studies
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