Pub Date : 2022-01-01DOI: 10.5797/jnet.ob.2022-1000
S. Miyachi, Sirintara (Pongpech) Singhara Na Ayudhaya, Jeyaledchumy Mahadevan, Timo Krings, M. Shapiro, E. Raz, E. Nossek, P. Nelson, H. Shigematsu
{"title":"In Memory of Kittipong Srivatanakul","authors":"S. Miyachi, Sirintara (Pongpech) Singhara Na Ayudhaya, Jeyaledchumy Mahadevan, Timo Krings, M. Shapiro, E. Raz, E. Nossek, P. Nelson, H. Shigematsu","doi":"10.5797/jnet.ob.2022-1000","DOIUrl":"https://doi.org/10.5797/jnet.ob.2022-1000","url":null,"abstract":"","PeriodicalId":34768,"journal":{"name":"JNET","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71059280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-21DOI: 10.5797/jnet.cr.2019-0036
Y. Tsuboi, Tomoaki Terada, H. Itokawa, S. Yamana, Michihisa Narikiyo, Norio Fujii, H. Nagasaki, Seiya Nagao, Chisaku Kambayashi
Objective: We report a case of ruptured brain stem arteriovenous malformation that was successfully treated by transvenous embolization in addition to transarterial embolization using Onyx. Case Presentation: A 61-year-old woman was admitted because of consciousness disorder following sudden-onset headache. CT revealed brain stem hemorrhage and MRI revealed abnormal vessels around the brainstem. Cerebral arteriovenous malformation on the right side of the pons was identified from an angiography. Her consciousness gradually improved from conservative treatment. Thereafter, endovascular treatment was performed. First, transarterial embolization with Onyx was performed to reduce the nidus as much as possible. Then, transvenous embolization for the remaining nidus was performed to completely embolize the cerebral arteriovenous malformation. No new neurological deficits were observed after treatment and no recurrence was noted on follow-up angiography 1 month after treatment. Conclusion: We treated the brainstem arteriovenous malformation using a combination of transvenous and transarterial embolizations. In suitable cases, transvenous embolization can be an alternative treatment for deep-seated cerebral arteriovenous malformations that are difficult to treat by transarterial embolization or direct surgery.
{"title":"A Case of Brainstem Arteriovenous Malformation Cured by Transvenous Embolization with Onyx","authors":"Y. Tsuboi, Tomoaki Terada, H. Itokawa, S. Yamana, Michihisa Narikiyo, Norio Fujii, H. Nagasaki, Seiya Nagao, Chisaku Kambayashi","doi":"10.5797/jnet.cr.2019-0036","DOIUrl":"https://doi.org/10.5797/jnet.cr.2019-0036","url":null,"abstract":"Objective: We report a case of ruptured brain stem arteriovenous malformation that was successfully treated by transvenous embolization in addition to transarterial embolization using Onyx. Case Presentation: A 61-year-old woman was admitted because of consciousness disorder following sudden-onset headache. CT revealed brain stem hemorrhage and MRI revealed abnormal vessels around the brainstem. Cerebral arteriovenous malformation on the right side of the pons was identified from an angiography. Her consciousness gradually improved from conservative treatment. Thereafter, endovascular treatment was performed. First, transarterial embolization with Onyx was performed to reduce the nidus as much as possible. Then, transvenous embolization for the remaining nidus was performed to completely embolize the cerebral arteriovenous malformation. No new neurological deficits were observed after treatment and no recurrence was noted on follow-up angiography 1 month after treatment. Conclusion: We treated the brainstem arteriovenous malformation using a combination of transvenous and transarterial embolizations. In suitable cases, transvenous embolization can be an alternative treatment for deep-seated cerebral arteriovenous malformations that are difficult to treat by transarterial embolization or direct surgery.","PeriodicalId":34768,"journal":{"name":"JNET","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5797/jnet.cr.2019-0036","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41373981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-18DOI: 10.5797/jnet.cr.2019-0043
A. Tsuji, H. Kayatani, K. Tsuji, Y. Yoshimura, T. Yokoi, T. Nakazawa, K. Nozaki
Objective: We report the first case of a vertebral artery (VA) dissecting aneurysm involving the posterior inferior cerebellar artery (PICA) treated by placing a stent on the PICA from the contralateral VA and parent artery occlusion in the acute hemorrhagic phase. Case Presentation: The patient was a 47-year-old man with World Federation of Neurosurgical Societies (WFNS) grade 3 subarachnoid hemorrhage (SAH) and a VA dissecting aneurysm involving the origin of the PICA. We approached from the contralateral VA, and placed a stent from the PICA to VA to preserve the PICA, and parent artery occlusion of the VA was performed. As of 6 months postoperatively, no rebleeding or recurrence of aneurysm has been observed. Conclusion: Although the use of stents in the acute phase is difficult, they can fully preserve the PICA and parent artery occlusion, and may be an effective treatment method to prevent rebleeding and chronic phase recurrence.
{"title":"A Case of Ruptured Vertebral Artery Dissection Involving the Origin of the Posterior Inferior Cerebellar Artery Was Conserved by Placing a Stent via the Contralateral Vertebral Artery","authors":"A. Tsuji, H. Kayatani, K. Tsuji, Y. Yoshimura, T. Yokoi, T. Nakazawa, K. Nozaki","doi":"10.5797/jnet.cr.2019-0043","DOIUrl":"https://doi.org/10.5797/jnet.cr.2019-0043","url":null,"abstract":"Objective: We report the first case of a vertebral artery (VA) dissecting aneurysm involving the posterior inferior cerebellar artery (PICA) treated by placing a stent on the PICA from the contralateral VA and parent artery occlusion in the acute hemorrhagic phase. Case Presentation: The patient was a 47-year-old man with World Federation of Neurosurgical Societies (WFNS) grade 3 subarachnoid hemorrhage (SAH) and a VA dissecting aneurysm involving the origin of the PICA. We approached from the contralateral VA, and placed a stent from the PICA to VA to preserve the PICA, and parent artery occlusion of the VA was performed. As of 6 months postoperatively, no rebleeding or recurrence of aneurysm has been observed. Conclusion: Although the use of stents in the acute phase is difficult, they can fully preserve the PICA and parent artery occlusion, and may be an effective treatment method to prevent rebleeding and chronic phase recurrence.","PeriodicalId":34768,"journal":{"name":"JNET","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46356572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-18DOI: 10.5797/jnet.oa.2019-0042
R. Doijiri, Naoto Kimura, Ken Takahashi, Hideaki Endo, Michiko Yokosawa, Hiroaki Takahashi, T. Sugawara, Takahiko Kikuchi
Objective: Insertable cardiac monitoring (ICM) systems are useful for diagnosing paroxysmal atrial fibrillation (PAF) in cryptogenic stroke (CS). We assessed the initial treatment outcome using insertable cardiac monitors in CS treated by endovascular reperfusion therapy. Methods: Of 102 consecutive acute ischemic stroke patients with large vessel occlusion (LVO) treated by endovascular therapy, we included 10 with CS who underwent insertable cardiac monitor placement between December 2016 and June 2018 at our hospital. Atrial fibrillation (AF) was determined by performing screening tests such as 12-lead electrocardiography (ECG), Holter ECG, and continued electrocardiographic monitoring for 3 days. Transesophageal echocardiogram (TEE) was essential to diagnose CS. We analyzed the parameters of AF and the time at which AF was first detected within 1 year. Results: There were eight (80%) male patients, and the median age was 68 (interquartile range [IQR]: 59–76) years. The parameters of AF were not outliers. The detection rate of AF at 12 months was 60%. The median time from onset of stroke to device insertion was 17 (range: 10–22) days, and the median time from device insertion to detection of the first AF episode was 52 (range: 12–344) days. Conclusion: The detection rate of AF in acute ischemic stroke patients with LVO treated by endovascular therapy was higher than that in previous reports.
{"title":"Treatment Outcome Using Insertable Cardiac Monitoring in Patients with Cryptogenic Stroke after Thrombectomy","authors":"R. Doijiri, Naoto Kimura, Ken Takahashi, Hideaki Endo, Michiko Yokosawa, Hiroaki Takahashi, T. Sugawara, Takahiko Kikuchi","doi":"10.5797/jnet.oa.2019-0042","DOIUrl":"https://doi.org/10.5797/jnet.oa.2019-0042","url":null,"abstract":"Objective: Insertable cardiac monitoring (ICM) systems are useful for diagnosing paroxysmal atrial fibrillation (PAF) in cryptogenic stroke (CS). We assessed the initial treatment outcome using insertable cardiac monitors in CS treated by endovascular reperfusion therapy. Methods: Of 102 consecutive acute ischemic stroke patients with large vessel occlusion (LVO) treated by endovascular therapy, we included 10 with CS who underwent insertable cardiac monitor placement between December 2016 and June 2018 at our hospital. Atrial fibrillation (AF) was determined by performing screening tests such as 12-lead electrocardiography (ECG), Holter ECG, and continued electrocardiographic monitoring for 3 days. Transesophageal echocardiogram (TEE) was essential to diagnose CS. We analyzed the parameters of AF and the time at which AF was first detected within 1 year. Results: There were eight (80%) male patients, and the median age was 68 (interquartile range [IQR]: 59–76) years. The parameters of AF were not outliers. The detection rate of AF at 12 months was 60%. The median time from onset of stroke to device insertion was 17 (range: 10–22) days, and the median time from device insertion to detection of the first AF episode was 52 (range: 12–344) days. Conclusion: The detection rate of AF in acute ischemic stroke patients with LVO treated by endovascular therapy was higher than that in previous reports.","PeriodicalId":34768,"journal":{"name":"JNET","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41949782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-18DOI: 10.5797/jnet.cr.2019-0044
S. Kawada, K. Sugiu
Objective: Spontaneous vertebral arteriovenous fistula (VAVF) is a rare vascular disorder. Herein, we report a case of high-flow VAVF with ipsilateral persistent primitive trigeminal artery (PPTA) treated by trans-arterial target embolization (TE) using balloon remodeling technique (BRT). Case Presentation: A 58-year-old woman with a medical history of non-tuberculous mycobacterial lung disease had complained of right-sided pulsatile tinnitus for 3 years; however, there were no symptoms due to brain or spinal cord dysfunction. DSA revealed high-flow VAVF in the right V3 segment at the C2 vertebral body level and ipsilateral PPTA. The multi-planar reconstruction (MPR) images of cone-beam CT (CB-CT) obtained from 3D rotational angiography (3D-RA) in the arterial phase were useful to evaluate the morphology of VAVF. The fistula was single and positioned in the V3 segment at the C2 vertebral body level. The venous side of the fistula had expanded into a spheroid-like shape. A planned trans-arterial TE was performed 39 months after diagnosis due to recurring lung hemorrhage. Using BRT, TE was successful by packing back from the spheroid-like space with coils. The spheroid-like space was located slightly caudal to the fistula, and occlusion balloon inflated just distal to the fistula was helpful to navigate the microcatheter. After 12 months, DSA showed no recurrence of VAVF. Conclusion: The MPR images of CB-CT obtained from 3D-RA were useful for evaluation of the morphological structure of VAVF. The BRT was useful for successful TE.
{"title":"A Case of Spontaneous High-flow Vertebral Arteriovenous Fistula Treated by Trans-arterial Target Embolization Using Balloon Remodeling Technique","authors":"S. Kawada, K. Sugiu","doi":"10.5797/jnet.cr.2019-0044","DOIUrl":"https://doi.org/10.5797/jnet.cr.2019-0044","url":null,"abstract":"Objective: Spontaneous vertebral arteriovenous fistula (VAVF) is a rare vascular disorder. Herein, we report a case of high-flow VAVF with ipsilateral persistent primitive trigeminal artery (PPTA) treated by trans-arterial target embolization (TE) using balloon remodeling technique (BRT). Case Presentation: A 58-year-old woman with a medical history of non-tuberculous mycobacterial lung disease had complained of right-sided pulsatile tinnitus for 3 years; however, there were no symptoms due to brain or spinal cord dysfunction. DSA revealed high-flow VAVF in the right V3 segment at the C2 vertebral body level and ipsilateral PPTA. The multi-planar reconstruction (MPR) images of cone-beam CT (CB-CT) obtained from 3D rotational angiography (3D-RA) in the arterial phase were useful to evaluate the morphology of VAVF. The fistula was single and positioned in the V3 segment at the C2 vertebral body level. The venous side of the fistula had expanded into a spheroid-like shape. A planned trans-arterial TE was performed 39 months after diagnosis due to recurring lung hemorrhage. Using BRT, TE was successful by packing back from the spheroid-like space with coils. The spheroid-like space was located slightly caudal to the fistula, and occlusion balloon inflated just distal to the fistula was helpful to navigate the microcatheter. After 12 months, DSA showed no recurrence of VAVF. Conclusion: The MPR images of CB-CT obtained from 3D-RA were useful for evaluation of the morphological structure of VAVF. The BRT was useful for successful TE.","PeriodicalId":34768,"journal":{"name":"JNET","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5797/jnet.cr.2019-0044","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42958816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-24DOI: 10.5797/JNET.CR.2018-0120
Akira Wakako, S. Nagahisa, M. Oeda, Hirotaka Kogame, A. Sadato
Objective: There are few reports of fungal aneurysms developing in the basilar artery where endovascular therapy has been provided. Cerebral infarction was observed before the occurrence of the aneurysm. The aneurysm ruptured repeatedly during treatment. Since the clinical course was complicated, it is reviewed in the literature. Case Presentation: A 71-year-old female patient receiving chemotherapy was admitted with a chief complaint of fever. On the day of hospitalization, right-sided paralysis appeared. MRI confirmed a pontine infarction. A sudden decrease in the consciousness level was observed on the 7th day of hospitalization. Head CT showed subarachnoid hemorrhage. The formation of a basilar artery aneurysm was confirmed on 3D-CTA. We suspected an infectious aneurysm and treated using coil embolization. This aneurysm ruptured repeatedly during treatment. The patient died on the 28th day of hospitalization. From the cerebrospinal fluid examination and autopsy results, subarachnoid hemorrhage due to ruptured infectious aneurysm caused by Aspergillus was diagnosed. Conclusion: An endosaccular embolization of an Aspergillus aneurysm caused repeated intraoperative rupture and the prognosis was poor.
{"title":"A Patient with Repeated Hemorrhage during Coil Embolization of Aspergillus Aneurysm Rupture","authors":"Akira Wakako, S. Nagahisa, M. Oeda, Hirotaka Kogame, A. Sadato","doi":"10.5797/JNET.CR.2018-0120","DOIUrl":"https://doi.org/10.5797/JNET.CR.2018-0120","url":null,"abstract":"Objective: There are few reports of fungal aneurysms developing in the basilar artery where endovascular therapy has been provided. Cerebral infarction was observed before the occurrence of the aneurysm. The aneurysm ruptured repeatedly during treatment. Since the clinical course was complicated, it is reviewed in the literature. Case Presentation: A 71-year-old female patient receiving chemotherapy was admitted with a chief complaint of fever. On the day of hospitalization, right-sided paralysis appeared. MRI confirmed a pontine infarction. A sudden decrease in the consciousness level was observed on the 7th day of hospitalization. Head CT showed subarachnoid hemorrhage. The formation of a basilar artery aneurysm was confirmed on 3D-CTA. We suspected an infectious aneurysm and treated using coil embolization. This aneurysm ruptured repeatedly during treatment. The patient died on the 28th day of hospitalization. From the cerebrospinal fluid examination and autopsy results, subarachnoid hemorrhage due to ruptured infectious aneurysm caused by Aspergillus was diagnosed. Conclusion: An endosaccular embolization of an Aspergillus aneurysm caused repeated intraoperative rupture and the prognosis was poor.","PeriodicalId":34768,"journal":{"name":"JNET","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44027430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-17DOI: 10.5797/JNET.CR.2018-0138
Yuichiro Tsurusaki, Kenta Takahara, Noriyuki Koga, T. Amano, S. Haga, S. Arihiro
Objective: We report a case of cerebral infarction with mechanical reperfusion therapy for tumor embolism caused by lung cancer. Case Presentation: The patient was a 72-year-old man. We performed emergency mechanical thrombectomy alone for acute left internal cerebral artery (ICA) occlusion and achieved complete reperfusion at the fifth pass with Trevo 4 × 20 mm. Pathologically, the embolus was diagnosed as squamous cell carcinoma. In chest contrast CT, lung cancer invaded the left atrium and pulmonary vein, diagnosed as tumor embolism by this invading tumor. Conclusion: We experienced a very rare case of tumor embolism caused by lung cancer. Although it was difficult to re-canalize, the strut structure of Trevo and push and fluff technique may have been effective against the hard embolus.
{"title":"A Case of Mechanical Reperfusion Therapy for Cerebral Infarction Induced by Tumor Embolism from Lung Cancer","authors":"Yuichiro Tsurusaki, Kenta Takahara, Noriyuki Koga, T. Amano, S. Haga, S. Arihiro","doi":"10.5797/JNET.CR.2018-0138","DOIUrl":"https://doi.org/10.5797/JNET.CR.2018-0138","url":null,"abstract":"Objective: We report a case of cerebral infarction with mechanical reperfusion therapy for tumor embolism caused by lung cancer. Case Presentation: The patient was a 72-year-old man. We performed emergency mechanical thrombectomy alone for acute left internal cerebral artery (ICA) occlusion and achieved complete reperfusion at the fifth pass with Trevo 4 × 20 mm. Pathologically, the embolus was diagnosed as squamous cell carcinoma. In chest contrast CT, lung cancer invaded the left atrium and pulmonary vein, diagnosed as tumor embolism by this invading tumor. Conclusion: We experienced a very rare case of tumor embolism caused by lung cancer. Although it was difficult to re-canalize, the strut structure of Trevo and push and fluff technique may have been effective against the hard embolus.","PeriodicalId":34768,"journal":{"name":"JNET","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5797/JNET.CR.2018-0138","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46944027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-22DOI: 10.5797/JNET.OA.2018-0116
Daisuke Izawa, H. Matsumoto, Hirokazu Nishiyama, N. Toki, Takumi Kawaguchi, Rie Yako, N. Nakao
Objective: This study evaluated the efficacy of middle meningeal artery (MMA) embolization for organized chronic subdural hematoma (OCSDH). Methods: Between 2013 and 2017 at our institution, 11 consecutive patients with 14 OCSDH lesions required MMA embolization, accounting for 4.5% of the 314 patients treated for chronic subdural hematoma (CSDH) in this period. Initially, all lesions underwent burr-hole surgery (BHS) under local anesthesia. At the regrowth, BHS was first performed under local anesthesia. OCSDH was diagnosed based on second-operative findings and postoperative CT or magnetic resonance imaging of the brain, and MMA embolization was performed for OCSDH. We investigated the efficacy of MMA embolization in reducing the hematoma and preventing regrowth of OCSDH. Results: In the second surgery, 12 lesions underwent BHS. Additionally, two lesions were treated with small craniotomy after BHS under local anesthesia. In all lesions, MMA embolization was performed within 3 weeks after the second surgery. In all, 12 lesions improved on brain CT within 2–4 weeks. Two lesions underwent craniotomy and membranectomy under general anesthesia, 2 and 10 days after MMA embolization. In one case, the BHS and small craniotomy were insufficient to reduce the mass effect. In the other case, infectious CSDH was diagnosed at craniotomy. Conclusions: MMA embolization may be effective additional modality for OCSDH after BHS.
{"title":"Efficacy of Middle Meningeal Artery Embolization for Organized Chronic Subdural Hematoma","authors":"Daisuke Izawa, H. Matsumoto, Hirokazu Nishiyama, N. Toki, Takumi Kawaguchi, Rie Yako, N. Nakao","doi":"10.5797/JNET.OA.2018-0116","DOIUrl":"https://doi.org/10.5797/JNET.OA.2018-0116","url":null,"abstract":"Objective: This study evaluated the efficacy of middle meningeal artery (MMA) embolization for organized chronic subdural hematoma (OCSDH). Methods: Between 2013 and 2017 at our institution, 11 consecutive patients with 14 OCSDH lesions required MMA embolization, accounting for 4.5% of the 314 patients treated for chronic subdural hematoma (CSDH) in this period. Initially, all lesions underwent burr-hole surgery (BHS) under local anesthesia. At the regrowth, BHS was first performed under local anesthesia. OCSDH was diagnosed based on second-operative findings and postoperative CT or magnetic resonance imaging of the brain, and MMA embolization was performed for OCSDH. We investigated the efficacy of MMA embolization in reducing the hematoma and preventing regrowth of OCSDH. Results: In the second surgery, 12 lesions underwent BHS. Additionally, two lesions were treated with small craniotomy after BHS under local anesthesia. In all lesions, MMA embolization was performed within 3 weeks after the second surgery. In all, 12 lesions improved on brain CT within 2–4 weeks. Two lesions underwent craniotomy and membranectomy under general anesthesia, 2 and 10 days after MMA embolization. In one case, the BHS and small craniotomy were insufficient to reduce the mass effect. In the other case, infectious CSDH was diagnosed at craniotomy. Conclusions: MMA embolization may be effective additional modality for OCSDH after BHS.","PeriodicalId":34768,"journal":{"name":"JNET","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5797/JNET.OA.2018-0116","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46018648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-16DOI: 10.5797/JNET.OA.2018-0134
N. Matsubara, R. Hiramatsu, Ryokichi Yagi, H. Ohnishi, S. Miyachi, G. Futamura, Y. Tsuji, Yangtae Park, S. Kawabata, T. Kuroiwa
Objective: The purpose of this study was to investigate the characteristics, time-line, and treatment results of in-hospital acute ischemic stroke due to large vessel occlusion (LVO) treated by mechanical thrombectomy. Methods: The authors investigated 10 patients (six males and four females; mean age 78.6 years, range 65–92) with in-hospital LVO treated by thrombectomy between January 2016 and July 2018 in our institute. Patient characteristics, procedural results, clinical outcome, and time-line data of thrombectomy (last well known [LWK]/onset, recognition, arterial puncture, and recanalization) were retrospectively evaluated. Results obtained from in-hospital LVO were compared with those from 13 patients with community-onset LVO (eight males and five females; mean age 78.3 years, range 45–87). Results: The initial admitting departments of in-hospital LVO were cardiology in six (60%) and hematology, otolaryngology, urology, and gastroenterology in one each (10%). The etiologies of ischemic stroke were cardioembolism in eight (80%), thrombosis in one (10%), and iatrogenic consequence in one (10%). The comorbid disease of in-hospital LVO included cardiac disease in eight (80%) and malignant tumor in four (40%) with overlapping. The factor contributing to in-hospital LVO was invasive procedure with withdrawal of antithrombotic agents in three (30%). The interval between LWK and recognition was a median of 60 minutes in in-hospital LVO, which was shorter than LWK-to-arrival time in communityonset LVO (medial 225 minutes). The interval between recognition and consultation to the neuroendovascular team was a median of 50 minutes. The recognition-to-puncture time was compared with arrival-to-puncture time in communityonset LVO. That presented no difference between them (median 130 vs 150 minutes). The LWK-to-recanalization time in in-hospital LVO was shorter than that in community-onset LVO (median 240 vs 495 minutes). The procedural results of thrombectomy demonstrated no differences between them. The rate of thrombolysis in cerebral infarction (TICI) 2b-3 was 70% in in-hospital vs 85% in community-onset LVO. The rate of favorable outcome (modified Rankin Scale [mRS] 0-2) at discharge was not different (30% vs 23%); however, higher rates of mortality and severe disability (mRS 5-6) were observed in patients with in-hospital LVO compared to those with community-onset LVO (40% vs 15%). Conclusion: In this series, the procedural results of thrombectomy were not different between in-hospital and communityonset LVO. The recognition-to-puncture time in in-hospital LVO was similar to the arrival-to-puncture time in community-onset LVO, although the LWK-to-recognition/recanalization time in in-hospital LVO was shorter compared with the LWK-toarrival/recanalization-time in community-onset LVO. The rate of clinical favorable outcome was similar, although a higher rate of poor outcome was observed in in-hospital LVO. Comorbid diseases may be associated with po
目的:探讨机械性血栓切除术治疗院内大血管闭塞性急性缺血性脑卒中的特点、时间线和治疗效果。方法:作者调查了2016年1月至2018年7月在我所接受血栓切除术治疗的10名住院LVO患者(6名男性和4名女性;平均年龄78.6岁,范围65-92岁)。回顾性评估血栓切除术的患者特征、手术结果、临床结果和时间线数据(最后一次已知[LWK]/发病、识别、动脉穿刺和再通)。将住院LVO的结果与13名社区发病LVO患者的结果进行比较(8名男性和5名女性;平均年龄78.3岁,范围45-87岁)。结果:住院LVO的最初入院科室是心脏科6个(60%),血液科、耳鼻喉科、泌尿科和胃肠科各1个(10%)。缺血性中风的病因是8例(80%)的心脏栓塞,1例(10%)的血栓形成和1例(10%)的医源性后果。住院LVO的合并症包括心脏病8例(80%)和恶性肿瘤4例(40%),并有重叠。导致院内LVO的因素是侵入性手术,其中三例(30%)患者停药。在住院LVO中,LWK和识别之间的间隔中值为60分钟,比LWK到社区LVO的到达时间(中间225分钟)短。从识别到咨询神经血管内团队的时间间隔中位数为50分钟。将社区集合LVO中对穿刺时间的识别与到达穿刺时间进行比较。这在他们之间没有差异(中位数为130分钟与150分钟)。住院LVO患者的LWK至再通时间短于社区发病LVO患者(中位数240 vs 495分钟)。血栓切除术的手术结果显示两者之间没有差异。脑梗死2b-3的住院溶栓率为70%,而社区发病LVO的溶栓率为85%。出院时的良好结局率(改良兰金量表[mRS]0-2)没有差异(30%对23%);然而,与社区发病的LVO患者相比,住院LVO患者的死亡率和严重残疾率(mRS 5-6)更高(40%对15%)。结论:在本系列中,住院和社区LVO的血栓切除术结果没有差异。住院LVO中对穿刺的识别时间与社区发病LVO中到达穿刺的时间相似,尽管住院LVO的LWK到识别/再通的时间比社区发病LVO的LWK到达/再通时间短。尽管在住院LVO中观察到不良结果的发生率较高,但临床上的良好结果发生率相似。合并症可能与LVO导致的住院缺血性卒中的不良结局有关。
{"title":"Characteristics and Treatment Results of In-hospital Acute Ischemic Stroke due to Large Vessel Occlusion Treated by Mechanical Thrombectomy","authors":"N. Matsubara, R. Hiramatsu, Ryokichi Yagi, H. Ohnishi, S. Miyachi, G. Futamura, Y. Tsuji, Yangtae Park, S. Kawabata, T. Kuroiwa","doi":"10.5797/JNET.OA.2018-0134","DOIUrl":"https://doi.org/10.5797/JNET.OA.2018-0134","url":null,"abstract":"Objective: The purpose of this study was to investigate the characteristics, time-line, and treatment results of in-hospital acute ischemic stroke due to large vessel occlusion (LVO) treated by mechanical thrombectomy. Methods: The authors investigated 10 patients (six males and four females; mean age 78.6 years, range 65–92) with in-hospital LVO treated by thrombectomy between January 2016 and July 2018 in our institute. Patient characteristics, procedural results, clinical outcome, and time-line data of thrombectomy (last well known [LWK]/onset, recognition, arterial puncture, and recanalization) were retrospectively evaluated. Results obtained from in-hospital LVO were compared with those from 13 patients with community-onset LVO (eight males and five females; mean age 78.3 years, range 45–87). Results: The initial admitting departments of in-hospital LVO were cardiology in six (60%) and hematology, otolaryngology, urology, and gastroenterology in one each (10%). The etiologies of ischemic stroke were cardioembolism in eight (80%), thrombosis in one (10%), and iatrogenic consequence in one (10%). The comorbid disease of in-hospital LVO included cardiac disease in eight (80%) and malignant tumor in four (40%) with overlapping. The factor contributing to in-hospital LVO was invasive procedure with withdrawal of antithrombotic agents in three (30%). The interval between LWK and recognition was a median of 60 minutes in in-hospital LVO, which was shorter than LWK-to-arrival time in communityonset LVO (medial 225 minutes). The interval between recognition and consultation to the neuroendovascular team was a median of 50 minutes. The recognition-to-puncture time was compared with arrival-to-puncture time in communityonset LVO. That presented no difference between them (median 130 vs 150 minutes). The LWK-to-recanalization time in in-hospital LVO was shorter than that in community-onset LVO (median 240 vs 495 minutes). The procedural results of thrombectomy demonstrated no differences between them. The rate of thrombolysis in cerebral infarction (TICI) 2b-3 was 70% in in-hospital vs 85% in community-onset LVO. The rate of favorable outcome (modified Rankin Scale [mRS] 0-2) at discharge was not different (30% vs 23%); however, higher rates of mortality and severe disability (mRS 5-6) were observed in patients with in-hospital LVO compared to those with community-onset LVO (40% vs 15%). Conclusion: In this series, the procedural results of thrombectomy were not different between in-hospital and communityonset LVO. The recognition-to-puncture time in in-hospital LVO was similar to the arrival-to-puncture time in community-onset LVO, although the LWK-to-recognition/recanalization time in in-hospital LVO was shorter compared with the LWK-toarrival/recanalization-time in community-onset LVO. The rate of clinical favorable outcome was similar, although a higher rate of poor outcome was observed in in-hospital LVO. Comorbid diseases may be associated with po","PeriodicalId":34768,"journal":{"name":"JNET","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45620274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}