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In Memory of Kittipong Srivatanakul 纪念基蒂蓬·斯里瓦塔纳库尔
Pub Date : 2022-01-01 DOI: 10.5797/jnet.ob.2022-1000
S. Miyachi, Sirintara (Pongpech) Singhara Na Ayudhaya, Jeyaledchumy Mahadevan, Timo Krings, M. Shapiro, E. Raz, E. Nossek, P. Nelson, H. Shigematsu
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引用次数: 0
A Case of Brainstem Arteriovenous Malformation Cured by Transvenous Embolization with Onyx 玛瑙经静脉栓塞治疗脑干动静脉畸形1例
Pub Date : 2019-10-21 DOI: 10.5797/jnet.cr.2019-0036
Y. Tsuboi, Tomoaki Terada, H. Itokawa, S. Yamana, Michihisa Narikiyo, Norio Fujii, H. Nagasaki, Seiya Nagao, Chisaku Kambayashi
Objective: We report a case of ruptured brain stem arteriovenous malformation that was successfully treated by transvenous embolization in addition to transarterial embolization using Onyx. Case Presentation: A 61-year-old woman was admitted because of consciousness disorder following sudden-onset headache. CT revealed brain stem hemorrhage and MRI revealed abnormal vessels around the brainstem. Cerebral arteriovenous malformation on the right side of the pons was identified from an angiography. Her consciousness gradually improved from conservative treatment. Thereafter, endovascular treatment was performed. First, transarterial embolization with Onyx was performed to reduce the nidus as much as possible. Then, transvenous embolization for the remaining nidus was performed to completely embolize the cerebral arteriovenous malformation. No new neurological deficits were observed after treatment and no recurrence was noted on follow-up angiography 1 month after treatment. Conclusion: We treated the brainstem arteriovenous malformation using a combination of transvenous and transarterial embolizations. In suitable cases, transvenous embolization can be an alternative treatment for deep-seated cerebral arteriovenous malformations that are difficult to treat by transarterial embolization or direct surgery.
目的:我们报告一例脑干动静脉畸形破裂的病例,该病例在使用Onyx经动脉栓塞的基础上,经静脉栓塞成功治疗。病例介绍:一位61岁的女性因突发性头痛后意识障碍入院。CT显示脑干出血,MRI显示脑干周围血管异常。脑桥右侧的脑动静脉畸形是通过血管造影术确认的。经过保守治疗,她的意识逐渐好转。之后,进行血管内治疗。首先,用玛瑙经动脉栓塞以尽可能减少病灶。然后,对剩余的病灶进行经静脉栓塞,以完全栓塞脑动静脉畸形。治疗后未观察到新的神经功能缺损,治疗后1个月随访血管造影术未发现复发。结论:我们采用经静脉和经动脉栓塞相结合的方法治疗脑干动静脉畸形。在合适的情况下,经静脉栓塞可以作为深部脑动静脉畸形的替代治疗方法,这些畸形难以通过动脉栓塞或直接手术治疗。
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引用次数: 0
A Case of Ruptured Vertebral Artery Dissection Involving the Origin of the Posterior Inferior Cerebellar Artery Was Conserved by Placing a Stent via the Contralateral Vertebral Artery 一例涉及小脑后下动脉起源的椎动脉破裂夹层通过对侧椎动脉放置支架得以保存
Pub Date : 2019-10-18 DOI: 10.5797/jnet.cr.2019-0043
A. Tsuji, H. Kayatani, K. Tsuji, Y. Yoshimura, T. Yokoi, T. Nakazawa, K. Nozaki
Objective: We report the first case of a vertebral artery (VA) dissecting aneurysm involving the posterior inferior cerebellar artery (PICA) treated by placing a stent on the PICA from the contralateral VA and parent artery occlusion in the acute hemorrhagic phase. Case Presentation: The patient was a 47-year-old man with World Federation of Neurosurgical Societies (WFNS) grade 3 subarachnoid hemorrhage (SAH) and a VA dissecting aneurysm involving the origin of the PICA. We approached from the contralateral VA, and placed a stent from the PICA to VA to preserve the PICA, and parent artery occlusion of the VA was performed. As of 6 months postoperatively, no rebleeding or recurrence of aneurysm has been observed. Conclusion: Although the use of stents in the acute phase is difficult, they can fully preserve the PICA and parent artery occlusion, and may be an effective treatment method to prevent rebleeding and chronic phase recurrence.
目的:我们报告第一例涉及小脑后下动脉(PICA)的椎动脉夹层动脉瘤,在急性出血期由对侧小脑后下动脉和母动脉闭塞的PICA上放置支架治疗。病例介绍:患者是一名47岁的男性,患有世界神经外科学会联合会(WFNS)三级蛛网膜下腔出血(SAH)和一个涉及异食癖起源的VA夹层动脉瘤。我们从对侧VA入路,从异位静脉到VA放置支架以保存异位静脉,并对VA进行母动脉闭塞。术后6个月未见动脉瘤再出血或复发。结论:虽然急性期支架使用困难,但支架能充分保留异食静脉和母动脉闭塞,是预防再出血和慢性期复发的有效治疗方法。
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引用次数: 0
Treatment Outcome Using Insertable Cardiac Monitoring in Patients with Cryptogenic Stroke after Thrombectomy 插入式心脏监护在血栓切除术后隐源性卒中患者中的治疗效果
Pub Date : 2019-10-18 DOI: 10.5797/jnet.oa.2019-0042
R. Doijiri, Naoto Kimura, Ken Takahashi, Hideaki Endo, Michiko Yokosawa, Hiroaki Takahashi, T. Sugawara, Takahiko Kikuchi
Objective: Insertable cardiac monitoring (ICM) systems are useful for diagnosing paroxysmal atrial fibrillation (PAF) in cryptogenic stroke (CS). We assessed the initial treatment outcome using insertable cardiac monitors in CS treated by endovascular reperfusion therapy. Methods: Of 102 consecutive acute ischemic stroke patients with large vessel occlusion (LVO) treated by endovascular therapy, we included 10 with CS who underwent insertable cardiac monitor placement between December 2016 and June 2018 at our hospital. Atrial fibrillation (AF) was determined by performing screening tests such as 12-lead electrocardiography (ECG), Holter ECG, and continued electrocardiographic monitoring for 3 days. Transesophageal echocardiogram (TEE) was essential to diagnose CS. We analyzed the parameters of AF and the time at which AF was first detected within 1 year. Results: There were eight (80%) male patients, and the median age was 68 (interquartile range [IQR]: 59–76) years. The parameters of AF were not outliers. The detection rate of AF at 12 months was 60%. The median time from onset of stroke to device insertion was 17 (range: 10–22) days, and the median time from device insertion to detection of the first AF episode was 52 (range: 12–344) days. Conclusion: The detection rate of AF in acute ischemic stroke patients with LVO treated by endovascular therapy was higher than that in previous reports.
目的:插入式心脏监测(ICM)系统可用于诊断隐源性卒中(CS)中的阵发性心房颤动(PAF)。我们在接受血管内再灌注治疗的CS中使用插入式心脏监测仪评估了初步治疗结果。方法:在102例连续接受血管内治疗的急性缺血性脑卒中大血管闭塞(LVO)患者中,我们纳入了10例CS患者,他们于2016年12月至2018年6月在我院接受了可插入式心脏监测仪植入术。心房颤动(AF)是通过进行筛选测试来确定的,如12导联心电图(ECG)、动态心电图和持续3天的心电图监测。经食道超声心动图(TEE)对CS的诊断至关重要。我们分析了房颤的参数和1年内首次检测到房颤的时间。结果:共有8名(80%)男性患者,中位年龄为68岁(四分位间距[IQR]:59-76)。AF的参数不是异常值。12个月时AF的检出率为60%。从中风发作到植入装置的中位时间为17天(范围:10-22),从植入装置到检测到第一次房颤发作的中位日期为52天(范围为12-344)。结论:血管内治疗LVO的急性缺血性脑卒中患者AF检出率高于以往报道。
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引用次数: 0
A Case of Spontaneous High-flow Vertebral Arteriovenous Fistula Treated by Trans-arterial Target Embolization Using Balloon Remodeling Technique 经动脉靶栓塞球囊重塑技术治疗自发性高流量椎动静脉瘘1例
Pub Date : 2019-10-18 DOI: 10.5797/jnet.cr.2019-0044
S. Kawada, K. Sugiu
Objective: Spontaneous vertebral arteriovenous fistula (VAVF) is a rare vascular disorder. Herein, we report a case of high-flow VAVF with ipsilateral persistent primitive trigeminal artery (PPTA) treated by trans-arterial target embolization (TE) using balloon remodeling technique (BRT). Case Presentation: A 58-year-old woman with a medical history of non-tuberculous mycobacterial lung disease had complained of right-sided pulsatile tinnitus for 3 years; however, there were no symptoms due to brain or spinal cord dysfunction. DSA revealed high-flow VAVF in the right V3 segment at the C2 vertebral body level and ipsilateral PPTA. The multi-planar reconstruction (MPR) images of cone-beam CT (CB-CT) obtained from 3D rotational angiography (3D-RA) in the arterial phase were useful to evaluate the morphology of VAVF. The fistula was single and positioned in the V3 segment at the C2 vertebral body level. The venous side of the fistula had expanded into a spheroid-like shape. A planned trans-arterial TE was performed 39 months after diagnosis due to recurring lung hemorrhage. Using BRT, TE was successful by packing back from the spheroid-like space with coils. The spheroid-like space was located slightly caudal to the fistula, and occlusion balloon inflated just distal to the fistula was helpful to navigate the microcatheter. After 12 months, DSA showed no recurrence of VAVF. Conclusion: The MPR images of CB-CT obtained from 3D-RA were useful for evaluation of the morphological structure of VAVF. The BRT was useful for successful TE.
目的:自发性椎动静脉瘘(VAVF)是一种罕见的血管疾病。在此,我们报告了一例高流量VAVF伴同侧持久性原始三叉动脉(PPTA)的病例,该病例采用球囊重建技术(BRT)经动脉靶点栓塞(TE)治疗。病例介绍:一名58岁女性,有非结核分枝杆菌肺病病史,主诉右侧搏动性耳鸣3年;然而,没有任何由于大脑或脊髓功能障碍引起的症状。DSA显示C2椎体水平的右侧V3段和同侧PPTA有高流量VAVF。从动脉期的三维旋转血管造影术(3D-RA)中获得的锥束CT(CB-CT)的多平面重建(MPR)图像有助于评估VAVF的形态。瘘管是单一的,位于C2椎体水平的V3段。瘘管的静脉侧已经扩张成球状。由于复发性肺出血,在诊断后39个月进行了计划的经动脉TE。使用BRT,TE通过用线圈从类似球体的空间打包而获得成功。球状空间位于瘘管的尾部,在瘘管远端膨胀的闭塞球囊有助于引导微导管。12个月后,DSA显示VAVF无复发。结论:3D-RA获得的CB-CT MPR图像有助于评价VAVF的形态结构。快速公交系统对TE的成功非常有用。
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引用次数: 0
A Patient with Repeated Hemorrhage during Coil Embolization of Aspergillus Aneurysm Rupture 曲霉菌动脉瘤破裂线圈栓塞术中反复出血1例
Pub Date : 2019-06-24 DOI: 10.5797/JNET.CR.2018-0120
Akira Wakako, S. Nagahisa, M. Oeda, Hirotaka Kogame, A. Sadato
Objective: There are few reports of fungal aneurysms developing in the basilar artery where endovascular therapy has been provided. Cerebral infarction was observed before the occurrence of the aneurysm. The aneurysm ruptured repeatedly during treatment. Since the clinical course was complicated, it is reviewed in the literature. Case Presentation: A 71-year-old female patient receiving chemotherapy was admitted with a chief complaint of fever. On the day of hospitalization, right-sided paralysis appeared. MRI confirmed a pontine infarction. A sudden decrease in the consciousness level was observed on the 7th day of hospitalization. Head CT showed subarachnoid hemorrhage. The formation of a basilar artery aneurysm was confirmed on 3D-CTA. We suspected an infectious aneurysm and treated using coil embolization. This aneurysm ruptured repeatedly during treatment. The patient died on the 28th day of hospitalization. From the cerebrospinal fluid examination and autopsy results, subarachnoid hemorrhage due to ruptured infectious aneurysm caused by Aspergillus was diagnosed. Conclusion: An endosaccular embolization of an Aspergillus aneurysm caused repeated intraoperative rupture and the prognosis was poor.
目的:在提供血管内治疗的基底动脉内发生真菌性动脉瘤的报道很少。在动脉瘤发生前观察到脑梗死。动脉瘤在治疗过程中反复破裂。由于临床过程复杂,文献对此进行了综述。病例介绍:一位71岁接受化疗的女性患者因发烧而入院。住院当天,出现右侧麻痹。核磁共振成像证实了脑桥梗死。住院第7天观察到意识水平突然下降。头部CT显示蛛网膜下腔出血。在3D-CTA上证实了基底动脉瘤的形成。我们怀疑是感染性动脉瘤,并用线圈栓塞治疗。这个动脉瘤在治疗过程中反复破裂。患者在住院第28天死亡。根据脑脊液检查和尸检结果,诊断为曲霉菌引起的感染性动脉瘤破裂引起蛛网膜下腔出血。结论:一个曲霉菌动脉瘤的腔内栓塞导致术中多次破裂,预后不良。
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引用次数: 1
A Case of Mechanical Reperfusion Therapy for Cerebral Infarction Induced by Tumor Embolism from Lung Cancer 机械再灌注治疗肺癌肿瘤栓塞性脑梗死1例
Pub Date : 2019-06-17 DOI: 10.5797/JNET.CR.2018-0138
Yuichiro Tsurusaki, Kenta Takahara, Noriyuki Koga, T. Amano, S. Haga, S. Arihiro
Objective: We report a case of cerebral infarction with mechanical reperfusion therapy for tumor embolism caused by lung cancer. Case Presentation: The patient was a 72-year-old man. We performed emergency mechanical thrombectomy alone for acute left internal cerebral artery (ICA) occlusion and achieved complete reperfusion at the fifth pass with Trevo 4 × 20 mm. Pathologically, the embolus was diagnosed as squamous cell carcinoma. In chest contrast CT, lung cancer invaded the left atrium and pulmonary vein, diagnosed as tumor embolism by this invading tumor. Conclusion: We experienced a very rare case of tumor embolism caused by lung cancer. Although it was difficult to re-canalize, the strut structure of Trevo and push and fluff technique may have been effective against the hard embolus.
目的:报告一例肺癌致肿瘤栓塞脑梗死机械再灌注治疗。病例介绍:患者为72岁男性。我们对急性左大脑内动脉(ICA)闭塞进行了紧急机械取栓,并在第5次通过Trevo 4 × 20 mm实现了完全再灌注。病理诊断为鳞状细胞癌。胸部对比CT显示肺癌侵袭左心房及肺静脉,经肿瘤侵袭诊断为肿瘤栓塞。结论:我们经历了一例罕见的由肺癌引起的肿瘤栓塞。虽然很难再通,但Trevo的支撑结构和推软技术可能对硬栓子有效。
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引用次数: 10
Endovascular Therapy of Distal Anterior Cerebral Artery Aneurysms: Single-institution Clinical Experience with 47 Patients (49 Aneurysms) 脑前远端动脉瘤的血管内治疗:47例(49个动脉瘤)单院临床体会
Pub Date : 2019-06-03 DOI: 10.5797/JNET.OA.2019-0004
Kazumoto Suzuki, K. Yatomi, Munetaka Yamamoto, H. Oishi, H. Arai
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引用次数: 4
Efficacy of Middle Meningeal Artery Embolization for Organized Chronic Subdural Hematoma 脑膜中动脉栓塞治疗有组织慢性硬膜下血肿的疗效观察
Pub Date : 2019-05-22 DOI: 10.5797/JNET.OA.2018-0116
Daisuke Izawa, H. Matsumoto, Hirokazu Nishiyama, N. Toki, Takumi Kawaguchi, Rie Yako, N. Nakao
Objective: This study evaluated the efficacy of middle meningeal artery (MMA) embolization for organized chronic subdural hematoma (OCSDH). Methods: Between 2013 and 2017 at our institution, 11 consecutive patients with 14 OCSDH lesions required MMA embolization, accounting for 4.5% of the 314 patients treated for chronic subdural hematoma (CSDH) in this period. Initially, all lesions underwent burr-hole surgery (BHS) under local anesthesia. At the regrowth, BHS was first performed under local anesthesia. OCSDH was diagnosed based on second-operative findings and postoperative CT or magnetic resonance imaging of the brain, and MMA embolization was performed for OCSDH. We investigated the efficacy of MMA embolization in reducing the hematoma and preventing regrowth of OCSDH. Results: In the second surgery, 12 lesions underwent BHS. Additionally, two lesions were treated with small craniotomy after BHS under local anesthesia. In all lesions, MMA embolization was performed within 3 weeks after the second surgery. In all, 12 lesions improved on brain CT within 2–4 weeks. Two lesions underwent craniotomy and membranectomy under general anesthesia, 2 and 10 days after MMA embolization. In one case, the BHS and small craniotomy were insufficient to reduce the mass effect. In the other case, infectious CSDH was diagnosed at craniotomy. Conclusions: MMA embolization may be effective additional modality for OCSDH after BHS.
目的:评价脑膜中动脉栓塞治疗有组织慢性硬膜下血肿(OCSDH)的疗效。方法:2013年至2017年,我院连续11例14例OCSDH病变患者需要MMA栓塞,占同期314例慢性硬膜下血肿(CSDH)患者的4.5%。最初,所有病变在局部麻醉下进行钻孔手术(BHS)。在再生时,首先在局部麻醉下进行BHS。根据二次手术表现及术后脑CT或磁共振成像诊断为OCSDH,并对OCSDH进行MMA栓塞治疗。我们研究了MMA栓塞对减少血肿和防止OCSDH再生的效果。结果:在第二次手术中,12个病灶行BHS。另外,2例病灶在局麻下行小开颅治疗。在所有病变中,MMA栓塞在第二次手术后3周内进行。在2-4周内,12个病灶在脑部CT上得到改善。在MMA栓塞后2天和10天,在全身麻醉下分别行开颅和膜切除术。在1例中,BHS和小开颅术不足以减少肿块效应。另一例,感染性CSDH在开颅时被诊断。结论:MMA栓塞可能是治疗BHS后OCSDH的有效补充方式。
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引用次数: 1
Characteristics and Treatment Results of In-hospital Acute Ischemic Stroke due to Large Vessel Occlusion Treated by Mechanical Thrombectomy 机械性血栓切除术治疗院内大血管闭塞性急性缺血性脑卒中的特点及治疗效果
Pub Date : 2019-05-16 DOI: 10.5797/JNET.OA.2018-0134
N. Matsubara, R. Hiramatsu, Ryokichi Yagi, H. Ohnishi, S. Miyachi, G. Futamura, Y. Tsuji, Yangtae Park, S. Kawabata, T. Kuroiwa
Objective: The purpose of this study was to investigate the characteristics, time-line, and treatment results of in-hospital acute ischemic stroke due to large vessel occlusion (LVO) treated by mechanical thrombectomy. Methods: The authors investigated 10 patients (six males and four females; mean age 78.6 years, range 65–92) with in-hospital LVO treated by thrombectomy between January 2016 and July 2018 in our institute. Patient characteristics, procedural results, clinical outcome, and time-line data of thrombectomy (last well known [LWK]/onset, recognition, arterial puncture, and recanalization) were retrospectively evaluated. Results obtained from in-hospital LVO were compared with those from 13 patients with community-onset LVO (eight males and five females; mean age 78.3 years, range 45–87). Results: The initial admitting departments of in-hospital LVO were cardiology in six (60%) and hematology, otolaryngology, urology, and gastroenterology in one each (10%). The etiologies of ischemic stroke were cardioembolism in eight (80%), thrombosis in one (10%), and iatrogenic consequence in one (10%). The comorbid disease of in-hospital LVO included cardiac disease in eight (80%) and malignant tumor in four (40%) with overlapping. The factor contributing to in-hospital LVO was invasive procedure with withdrawal of antithrombotic agents in three (30%). The interval between LWK and recognition was a median of 60 minutes in in-hospital LVO, which was shorter than LWK-to-arrival time in communityonset LVO (medial 225 minutes). The interval between recognition and consultation to the neuroendovascular team was a median of 50 minutes. The recognition-to-puncture time was compared with arrival-to-puncture time in communityonset LVO. That presented no difference between them (median 130 vs 150 minutes). The LWK-to-recanalization time in in-hospital LVO was shorter than that in community-onset LVO (median 240 vs 495 minutes). The procedural results of thrombectomy demonstrated no differences between them. The rate of thrombolysis in cerebral infarction (TICI) 2b-3 was 70% in in-hospital vs 85% in community-onset LVO. The rate of favorable outcome (modified Rankin Scale [mRS] 0-2) at discharge was not different (30% vs 23%); however, higher rates of mortality and severe disability (mRS 5-6) were observed in patients with in-hospital LVO compared to those with community-onset LVO (40% vs 15%). Conclusion: In this series, the procedural results of thrombectomy were not different between in-hospital and communityonset LVO. The recognition-to-puncture time in in-hospital LVO was similar to the arrival-to-puncture time in community-onset LVO, although the LWK-to-recognition/recanalization time in in-hospital LVO was shorter compared with the LWK-toarrival/recanalization-time in community-onset LVO. The rate of clinical favorable outcome was similar, although a higher rate of poor outcome was observed in in-hospital LVO. Comorbid diseases may be associated with po
目的:探讨机械性血栓切除术治疗院内大血管闭塞性急性缺血性脑卒中的特点、时间线和治疗效果。方法:作者调查了2016年1月至2018年7月在我所接受血栓切除术治疗的10名住院LVO患者(6名男性和4名女性;平均年龄78.6岁,范围65-92岁)。回顾性评估血栓切除术的患者特征、手术结果、临床结果和时间线数据(最后一次已知[LWK]/发病、识别、动脉穿刺和再通)。将住院LVO的结果与13名社区发病LVO患者的结果进行比较(8名男性和5名女性;平均年龄78.3岁,范围45-87岁)。结果:住院LVO的最初入院科室是心脏科6个(60%),血液科、耳鼻喉科、泌尿科和胃肠科各1个(10%)。缺血性中风的病因是8例(80%)的心脏栓塞,1例(10%)的血栓形成和1例(10%)的医源性后果。住院LVO的合并症包括心脏病8例(80%)和恶性肿瘤4例(40%),并有重叠。导致院内LVO的因素是侵入性手术,其中三例(30%)患者停药。在住院LVO中,LWK和识别之间的间隔中值为60分钟,比LWK到社区LVO的到达时间(中间225分钟)短。从识别到咨询神经血管内团队的时间间隔中位数为50分钟。将社区集合LVO中对穿刺时间的识别与到达穿刺时间进行比较。这在他们之间没有差异(中位数为130分钟与150分钟)。住院LVO患者的LWK至再通时间短于社区发病LVO患者(中位数240 vs 495分钟)。血栓切除术的手术结果显示两者之间没有差异。脑梗死2b-3的住院溶栓率为70%,而社区发病LVO的溶栓率为85%。出院时的良好结局率(改良兰金量表[mRS]0-2)没有差异(30%对23%);然而,与社区发病的LVO患者相比,住院LVO患者的死亡率和严重残疾率(mRS 5-6)更高(40%对15%)。结论:在本系列中,住院和社区LVO的血栓切除术结果没有差异。住院LVO中对穿刺的识别时间与社区发病LVO中到达穿刺的时间相似,尽管住院LVO的LWK到识别/再通的时间比社区发病LVO的LWK到达/再通时间短。尽管在住院LVO中观察到不良结果的发生率较高,但临床上的良好结果发生率相似。合并症可能与LVO导致的住院缺血性卒中的不良结局有关。
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引用次数: 2
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JNET
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