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A Patient with Encephalopathy Following Coil Embolization of Cerebral Aneurysm and Extracranial Stent Placement 脑动脉瘤线圈栓塞及颅外支架置入术后脑病1例
Pub Date : 2019-02-07 DOI: 10.5797/JNET.CR.2018-0083
Y. Sagara, H. Kiyosue, M. Okahara, M. Oga, A. Kaga, Yosuke Kamenofuchi
Objective: We report a patient in whom encephalopathy developed after coil embolization of an unruptured basilar artery aneurysm and stent placement for vertebral artery stenosis. Case Presentation: A 69-year-old female. When the unruptured basilar artery aneurysm was treated with coil embolization, a balloon-expandable stent was placed for left vertebral artery stenosis, and treatment was completed without complication. Loss of appetite and lightheadedness developed from 2 weeks after discharge, and multiple FLAIR highintensity areas, and nodular contrast enhancement in the left vertebral artery territory were observed on MRI. Steroid pulse therapy was performed suspecting metal allergy and foreign body granuloma, and symptoms improved. Conclusion: Encephalopathy associated with foreign body granuloma and metal allergy may be caused by coil and stent placement. Patients should be sufficiently interviewed, and when allergies are suspected, reconsideration of the treatment method may be necessary in advance.
目的:我们报告一例未破裂基底动脉瘤的线圈栓塞和椎动脉狭窄的支架置入术后出现脑病的患者。病例介绍:一名69岁女性。对未破裂的基底动脉瘤进行线圈栓塞治疗时,放置球囊扩张支架治疗左椎动脉狭窄,治疗成功,无并发症。出院后2周开始出现食欲下降和头晕,MRI上观察到左侧椎动脉区域有多个FLAIR高强度区域和结节性增强。怀疑金属过敏和异物肉芽肿,进行类固醇脉冲治疗,症状得到改善。结论:放置线圈和支架可能引起与异物肉芽肿和金属过敏相关的脑病。患者应该接受充分的采访,当怀疑过敏时,可能有必要提前重新考虑治疗方法。
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引用次数: 0
Investigation of Safe Termination of Antiplatelet Therapy after LVIS Stent-assisted Cerebral Aneurysm Coiling LVIS支架辅助脑动脉瘤盘绕术后抗血小板治疗安全终止的探讨
Pub Date : 2019-02-07 DOI: 10.5797/JNET.OA.2018-0112
T. Wada, K. Takayama, K. Myouchin, M. Kotsugi, I. Nakagawa, Toshihiko Tanaka, S. Kurokawa, H. Nakase, K. Kichikawa
Objective: Patients who undergo stent-assisted cerebral aneurysm coiling require long-term antiplatelet therapy (AT). Recently, the low-profile visualized intraluminal support (LVIS) stent (LS) has been available for cerebral aneurysm treatment in Japan as a new design braided stent with excellent wall apposition due to manipulation even if the parent artery is tortuous, like the carotid siphon. The aim of this study was to evaluate whether AT could be terminated without increasing the risk of ischemic events among patients who have undergone LS-assisted cerebral aneurysm coiling. Methods: In all, 15 consecutive patients with 15 unruptured aneurysms who underwent LS-assisted cerebral aneurysm coiling and were confirmed to have neointimal formation by follow-up angiography at 3 months were evaluated in this study. All aneurysms were located in the internal carotid artery (ICA). Dual AT was given for 1 month, and then a single antiplatelet agent was given for 2 months until confirmation of neointimal formation. After confirmation of neointimal formation, AT was terminated. The incidences of ipsilateral ischemic events and stent occlusion, as evaluated by angiography or contrast-enhanced MRA, after termination of AT were prospectively assessed. Results: During follow-up, no ipsilateral ischemic events (mean, 10.3 months; range, 3.1–19.8 months) occurred, and no stent occlusion (mean, 8.0 months; range, 1–17.5 months) was observed in any cases. Conclusion: Termination of the antiplatelet drugs 3 months after the procedure may be safe who underwent LS-assisted
目的:接受支架辅助脑动脉瘤盘绕术的患者需要长期抗血小板治疗(AT)。最近,在日本,低剖面可视化管腔内支持(LVIS)支架(LS)已可用于脑动脉瘤治疗,作为一种新设计的编织支架,即使母动脉弯曲(如颈动脉虹吸管),也能通过操作获得良好的壁贴附。本研究的目的是评估在接受LS辅助脑动脉瘤盘绕术的患者中,AT是否可以在不增加缺血性事件风险的情况下终止。方法:本研究共评估了15例未破裂动脉瘤的连续15例患者,这些患者接受了LS辅助脑动脉瘤卷取术,并在3个月时通过随访血管造影证实有新生内膜形成。所有动脉瘤均位于颈内动脉(ICA)。给予双重AT 1个月,然后给予单一抗血小板药物2个月,直到确认新生内膜形成。在确认新生内膜形成后,终止AT。通过血管造影术或对比增强MRA评估AT终止后同侧缺血性事件和支架闭塞的发生率。结果:在随访期间,任何病例均未发生同侧缺血性事件(平均10.3个月;范围3.1-19.8个月),也未观察到支架闭塞(平均8.0个月,范围1-17.5个月)。结论:对于LS辅助的患者,术后3个月停止抗血小板药物治疗可能是安全的
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引用次数: 4
Mechanical Thrombectomy for Acute Ischemic Stroke Caused by Cardiac Papillary Fibroelastoma: A Case Report 机械取栓治疗心脏乳头状纤维弹性瘤所致急性缺血性脑卒中1例
Pub Date : 2019-01-09 DOI: 10.5797/JNET.CR.2018-0121
E. Abe, T. Mitsuhashi, K. Nishioka, Munetaka Yamamoto, R. Ikemura, K. Kudo, J. Tokugawa, M. Hishii, K. Fukuda, H. Oishi, H. Arai
Objective: Reperfusion by endovascular mechanical thrombectomy has been proven effective for patients with acute ischemic stroke. Although most embolization sources are thrombi, other types of clots could also be embolic sources. We report a sporadic case of acute ischemic stroke caused by mobilization of cardiac papillary fibroelastoma (CPF). Case Presentation: A 79-year-old man presented was hospitalized with chronic heart failure due to disdialysis syndrome. He developed sudden consciousness disturbance and was diagnosed with basilar artery occlusion. Mechanical thrombectomy with only one pass of the Penumbra 5MAX ACE (Penumbra Inc., Alameda, CA, USA) was successful with a direct aspiration first-pass technique. Histopathological examination of the papilla-shaped fragile clot with white granular surface, revealed papillary fibroelastoma. Slight improvement in his clinical symptoms was seen after thrombectomy, but the patient died of deterioration of the disdialysis syndrome. CPF diagnosis was based on the pathological findings of the embolus, not on transesophageal echocardiography (TEE) or open heart surgery due to disdialysis syndrome in our patient. In addition, the presence of cardiac tumor could not be confirmed in the autopsy. Conclusion: CPF is a rare benign cardiac tumor, which might cause cerebral infarction either directly or through thrombus formed by platelets and fibrin. While mechanical thrombectomy is safe and effective, but histopathological diagnosis of the aspirated clot can be recommended, especially if the appearance of the embolic material is unusual.
目的:血管内机械血栓切除术再灌注已被证明对急性缺血性脑卒中患者有效。尽管大多数栓塞来源是血栓,但其他类型的血栓也可能是栓塞来源。我们报告了一例由心脏乳头状纤维弹性瘤(CPF)动员引起的急性缺血性卒中的散发病例。病例介绍:一位79岁的男性因脱透析综合征导致慢性心力衰竭住院治疗。他突然出现意识障碍,被诊断为基底动脉闭塞。Penumbra 5MAX ACE(Penumbra股份有限公司,Alameda,CA,USA)仅一次通过的机械血栓切除术通过直接抽吸一次通过技术成功。组织病理学检查乳头状易碎凝块,表面有白色颗粒,显示乳头状纤维弹性瘤。血栓切除术后,他的临床症状略有改善,但患者死于脱透析综合征恶化。CPF的诊断是基于栓子的病理结果,而不是基于经食道超声心动图(TEE)或由于患者的脱透析综合征而进行的心脏直视手术。此外,尸检中无法确认是否存在心脏肿瘤。结论:CPF是一种罕见的良性心脏肿瘤,可直接或通过血小板和纤维蛋白形成的血栓引起脑梗死。虽然机械血栓切除术是安全有效的,但可以建议对吸入的血栓进行组织病理学诊断,尤其是在栓塞物质出现异常的情况下。
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引用次数: 1
Hypoglossal Canal Dural Arteriovenous Fistula Induced after Mechanical Thrombectomy for Acute Ischemic Stroke 急性缺血性脑卒中机械取栓术后引起的舌下管硬脑膜动静脉瘘
Pub Date : 2019-01-01 DOI: 10.5797/JNET.CR.2018-0042
K. Mizutani, K. Nakabayashi, Y. Aimi, Mitsuhiro Yoshida, Daimon Shiraishi, Tomoki Nawashiro, Y. Ito
Objective: In this study, we report a patient in whom a dural arteriovenous fistula (dAVF) developed after mechanical thrombectomy for acute ischemic stroke, and embolization was performed. Case Presentation: The patient was a 44-year-old male. He was brought to the emergency room of our hospital by ambulance with cervical pain. Head MRI revealed ischemic stroke related to right internal carotid artery occlusion. Mechanical thrombectomy was performed and thrombolysis in cerebral infarction (TICI) 2b recanalization was achieved. Middle cerebral artery (M2) occlusion and internal carotid artery dissection were observed. Follow-up was conducted. The postoperative course was favorable, and he was referred to another hospital for rehabilitation. However, cerebral angiography 4 months after surgery showed a dAVF. Transarterial embolization was performed. The postoperative course was uneventful and she was discharged. Conclusion: In the present case, dissection-related dilation/elevation of the internal carotid artery may have resulted in venous compression, leading to the development of a dAVF. We could confirm these serial changes in images before and after its development.
目的:在本研究中,我们报告了一例急性缺血性脑卒中机械取栓后出现硬脑膜动静脉瘘(dAVF)并进行栓塞治疗的患者。病例介绍:患者男,44岁。他因为颈椎疼痛被救护车送到了我们医院的急诊室。头部MRI显示缺血性脑卒中与右侧颈内动脉闭塞有关。机械取栓,实现脑梗死(TICI) 2b再通溶栓。观察大脑中动脉(M2)闭塞及颈内动脉剥离。进行了随访。术后过程良好,他被转到另一家医院进行康复治疗。然而,术后4个月脑血管造影显示dAVF。经动脉栓塞。术后过程顺利,她出院了。结论:在本病例中,与解剖相关的颈内动脉扩张/抬高可能导致静脉压迫,导致dAVF的发展。我们可以在显影前后的图像中确认这些连续的变化。
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引用次数: 0
Stent Folding Deformation of PRECISE and PROTÉGÉ during Carotid Artery Stenting: Two Case Reports 颈动脉支架植入术中支架折叠变形的准确性和PROTÉGÉ: 2例报告
Pub Date : 2019-01-01 DOI: 10.5797/jnet.cr.2018-0143
Masato Naraoka, N. Shimamura, Naoya Matsuda, Takeshi Katagai, Nozomi Fujiwara, H. Ohkuma
Objective: We report two cases of folding deformation of open-cell stents that occurred during carotid artery stenting (CAS) for internal carotid artery (ICA) stenosis. Case Presentations: Case 1: A 64-year-old man was diagnosed with asymptomatic right ICA severe stenosis. The stenosis was eccentric, comprising soft plaque with calcification. CAS was performed by standard procedure under protection with MOMA (Medtronic, Minneapolis, MN, USA) and GuardWire (Medtronic). We attempted post-dilation two times because PRECISE (Cordis, Miami, FL, USA) stent did not sufficiently dilate. Cone-beam CT showed a folding deformation of the stent. Case 2: A 60-year-old man was diagnosed with asymptomatic left carotid artery severe stenosis 5 years after radiation therapy for esophageal carcinoma. The stenosis was long, comprising soft plaque without calcification. CAS was performed under protection with MOMA and GuardWire. A PROTÉGÉ (Covidien, Irvine, CA, USA) stent was placed in the etiologic portion. After post-dilation, intravascular ultrasound (IVUS) examination showed suspected in-stent plaque protrusion, but cone-beam CT revealed a folding deformation of the PROTÉGÉ. We did not try any additional treatment. Both patients had no ischemic complications after the procedure and no infarction was detected on MRI. Conclusion: We reported two cases of folding deformation with PRECISE or PROTÉGÉ. In addition to careful attention to not using an oversized stent, it is important to select a protection device and a balloon as a device to avoid deformation. It is difficult to predict or repair stent deformity. Continuation of antiplatelet therapy and long-term follow-up are required.
目的:报告两例颈内动脉(ICA)狭窄行颈动脉支架置入术时开放性支架发生折叠变形的病例。病例介绍:病例1:一名64岁男性被诊断为无症状的右侧ICA严重狭窄。狭窄偏心性,包括软斑块伴钙化。在MOMA (Medtronic, Minneapolis, MN, USA)和GuardWire (Medtronic)的保护下,按照标准程序进行CAS。由于PRECISE (Cordis, Miami, FL, USA)支架没有充分扩张,我们尝试了两次扩张后支架。锥形梁CT显示支架折叠变形。病例2:60岁男性食管癌放射治疗5年后诊断为无症状左颈动脉严重狭窄。狭窄较长,包括无钙化的软斑块。在MOMA和GuardWire的保护下进行CAS。在病因部分放置PROTÉGÉ (Covidien, Irvine, CA, USA)支架。扩张后血管内超声(IVUS)检查显示疑似支架内斑块突出,但锥束CT显示PROTÉGÉ折叠变形。我们没有尝试任何额外的治疗。两例患者术后均无缺血性并发症,MRI未发现梗死。结论:我们报告了2例使用PRECISE或PROTÉGÉ进行折叠变形的病例。除了要注意不要使用过大的支架外,重要的是要选择保护装置和气囊作为避免变形的装置。支架畸形很难预测或修复。需要继续抗血小板治疗和长期随访。
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引用次数: 2
Internal Carotid Artery Injury due to Aspiration Technique from Balloon Guide Catheter on Acute Thrombectomy: A Case Report 急性取栓术中球囊导尿管穿刺技术致颈内动脉损伤1例
Pub Date : 2019-01-01 DOI: 10.5797/JNET.CR.2018-0144
Akikazu Nakamura, A. Kawashima, M. Hayashi, Kazutoshi Hashimoto, Ayumi Nagahara, T. Arai, T. Kawamata
Objective: Acute large vessel occlusion is treated with endovascular thrombectomy. We encountered a patient in whom the internal carotid artery (ICA) was injured by direct aspiration through a balloon guide catheter (BGC). Case Presentation: The patient was an 82-year-old woman being treated with oral warfarin for atrial fibrillation. Endovascular thrombectomy was performed for right ICA occlusion presented with left hemiplegia when direct aspiration was applied through BGC which placed into the right ICA, extravasation was noted on imaging immediately after its application. Hemostasis was acquired by coil embolization, but extensive subarachnoid hemorrhage was noted on postoperative CT and the patient died after 3 days. Conclusion: The direct aspiration technique through BGC should be carefully performed because it may have a risk of vascular injury.
目的:采用血管内取栓术治疗急性大血管闭塞。我们遇到了一位通过球囊引导导管(BGC)直接抽吸导致颈内动脉(ICA)损伤的患者。病例介绍:患者是一名82岁的女性,口服华法林治疗心房颤动。左偏瘫右ICA闭塞行血管内取栓术,经BGC直接吸入右ICA,即刻显像发现外渗。通过线圈栓塞止血,但术后CT显示广泛的蛛网膜下腔出血,患者于3天后死亡。结论:经BGC直接抽吸术有血管损伤的危险,应谨慎操作。
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引用次数: 2
Case of a Patient Who Developed Basilar Artery Occlusion after Treatment of Traumatic Vertebral Artery Dissection with Proximal Coil Occlusion 外伤性椎动脉夹层合并近端线圈闭塞治疗后发生基底动脉闭塞1例
Pub Date : 2019-01-01 DOI: 10.5797/jnet.cr.2019-0010
Azusa Yonezawa, H. Neki, S. Mizuhashi, Toshihiro Otsuka, Eisuke Tsukagoshi, F. Yamane, S. Kohyama
Objective: To examine a case of basilar artery (BA) occlusion caused by traumatic vertebral artery (VA) dissection after incomplete endovascular therapy. Case Presentation: A 32-year-old man who got caught sustained injuries in a truck accident wherein he was stuck between two trucks was transported to a nearby hospital. Stenting was performed for the left common carotid artery (CCA). For left VA dissection, coil embolization of the VA was performed to prevent thromboembolic infarction because floating thrombus was found at the V3 segment. On postoperative day 1, he exhibited conscious disturbance. MRA revealed BA occlusion. Upon transfer to our hospital, thrombectomy was performed. After revascularization, the patient was alert. Conclusion: Although optimal treatment of traumatic VA injury is still debated, proximal coil occlusion is regarded as an effective preventive treatment for thromboembolic stroke. In case of VA dissection with floating thrombus, proximal VA occlusion is insufficient to prevent thromboembolic stroke, and thrombus capture should be considered.
目的:观察1例外伤性椎动脉剥离后不完全血管内治疗引起的基底动脉闭塞。病例介绍:一名32岁的男子在一次卡车事故中受伤,他被卡在两辆卡车之间,被送往附近的医院。左侧颈总动脉(CCA)行支架植入术。对于左室间隔夹层,由于在V3段发现漂浮血栓,对左室间隔进行线圈栓塞以防止血栓栓塞性梗死。术后第1天,患者出现意识障碍。MRA显示BA闭塞。转至我院后,行取栓术。血运重建术后,病人神志清醒。结论:尽管外伤性VA损伤的最佳治疗方法仍存在争议,近端线圈闭塞被认为是血栓栓塞性卒中的有效预防治疗方法。对于游离血栓的VA夹层,近端VA闭塞不足以预防血栓栓塞性卒中,应考虑血栓捕获。
{"title":"Case of a Patient Who Developed Basilar Artery Occlusion after Treatment of Traumatic Vertebral Artery Dissection with Proximal Coil Occlusion","authors":"Azusa Yonezawa, H. Neki, S. Mizuhashi, Toshihiro Otsuka, Eisuke Tsukagoshi, F. Yamane, S. Kohyama","doi":"10.5797/jnet.cr.2019-0010","DOIUrl":"https://doi.org/10.5797/jnet.cr.2019-0010","url":null,"abstract":"Objective: To examine a case of basilar artery (BA) occlusion caused by traumatic vertebral artery (VA) dissection after incomplete endovascular therapy. Case Presentation: A 32-year-old man who got caught sustained injuries in a truck accident wherein he was stuck between two trucks was transported to a nearby hospital. Stenting was performed for the left common carotid artery (CCA). For left VA dissection, coil embolization of the VA was performed to prevent thromboembolic infarction because floating thrombus was found at the V3 segment. On postoperative day 1, he exhibited conscious disturbance. MRA revealed BA occlusion. Upon transfer to our hospital, thrombectomy was performed. After revascularization, the patient was alert. Conclusion: Although optimal treatment of traumatic VA injury is still debated, proximal coil occlusion is regarded as an effective preventive treatment for thromboembolic stroke. In case of VA dissection with floating thrombus, proximal VA occlusion is insufficient to prevent thromboembolic stroke, and thrombus capture should be considered.","PeriodicalId":34768,"journal":{"name":"JNET","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71056547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Orbital Dural Arteriovenous Fistula with Exophthalmos Treated by Transarterial Embolization 经动脉栓塞治疗眼眶硬脑膜动静脉瘘伴眼球突出1例
Pub Date : 2019-01-01 DOI: 10.5797/JNET.TN.2018-0110
T. Terakado, Y. Nakai, Kazuaki Tsukada, Takahito Nishihira, H. Kohzuki, T. Konishi, M. Shiigai, K. Uemura
Objective: Transarterial embolization (TAE) for dural arteriovenous fistula (dAVF) is sometimes risky because of dangerous anastomosis. We successfully treated orbital apex dAVF by blocking back-flow to the internal carotid artery and ophthalmic artery with coil and balloon. Case Presentation: A 51-year-old man had red right eye and exophthalmos, and was diagnosed with right orbital apex dAVF. TAE using n-butyl-2-cyanoacrylate (NBCA)/lipiodol mixture via the artery of the superior orbital fissure was performed under flow control of the internal carotid artery and ophthalmic artery with balloon microcatheter and temporary placing of detachable coil. After the treatment, the shunt disappeared and the symptoms were improved. Conclusion: A proper understanding of dangerous anastomosis is important for safe and effective use of TAE for dAVF.
目的:经动脉栓塞治疗硬脑膜动静脉瘘(dAVF)有时因吻合危险而存在风险。我们成功地用线圈和球囊阻断内颈动脉和眼动脉的回流。病例介绍:51岁男性,右眼红肿,眼球突出,诊断为右眼眶尖dAVF。采用正丁基-2-氰基丙烯酸酯(NBCA)/脂醇混合物经眶上裂动脉行眶内动脉及眼动脉血流控制下气囊微导管及临时放置可拆卸线圈行眶上裂动脉TAE。治疗后分流消失,症状改善。结论:正确认识吻合术的危险性,对安全有效地使用TAE治疗大室性房颤具有重要意义。
{"title":"A Case of Orbital Dural Arteriovenous Fistula with Exophthalmos Treated by Transarterial Embolization","authors":"T. Terakado, Y. Nakai, Kazuaki Tsukada, Takahito Nishihira, H. Kohzuki, T. Konishi, M. Shiigai, K. Uemura","doi":"10.5797/JNET.TN.2018-0110","DOIUrl":"https://doi.org/10.5797/JNET.TN.2018-0110","url":null,"abstract":"Objective: Transarterial embolization (TAE) for dural arteriovenous fistula (dAVF) is sometimes risky because of dangerous anastomosis. We successfully treated orbital apex dAVF by blocking back-flow to the internal carotid artery and ophthalmic artery with coil and balloon. Case Presentation: A 51-year-old man had red right eye and exophthalmos, and was diagnosed with right orbital apex dAVF. TAE using n-butyl-2-cyanoacrylate (NBCA)/lipiodol mixture via the artery of the superior orbital fissure was performed under flow control of the internal carotid artery and ophthalmic artery with balloon microcatheter and temporary placing of detachable coil. After the treatment, the shunt disappeared and the symptoms were improved. Conclusion: A proper understanding of dangerous anastomosis is important for safe and effective use of TAE for dAVF.","PeriodicalId":34768,"journal":{"name":"JNET","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5797/JNET.TN.2018-0110","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71061720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Usefulness of a Microcatheter with a Short and Acute Angled Tip Made from an Excelsior SL-10 Pre-shaped S Catheter Preserving Its Distal Curve 由Excelsior SL-10预成形S型导管制成的短尖角微导管保留其远端曲线的实用性
Pub Date : 2019-01-01 DOI: 10.5797/jnet.oa.2019-0030
K. Hoya, Kazuya Nakamura, H. Nishido, Akihiro Nishikawa, Kenta Ohara, S. Miyamoto, K. Wakui
Objective: A method to create a microcatheter with a short and acute-angled tip using an Excelsior SL-10 pre-shaped S catheter (Stryker, Kalamazoo, MI, USA) by straightening its proximal curve is described. Its clinical application, in which a guidewire and a microcatheter are led into a distal artery branching sharply to prepare stent deployment, is presented. Methods: The proximal curve of a catheter was introduced into a disposable 18-gauge blunt needle. The needle was heated using a heat gun so as to heat and straighten only the proximal curve and to preserve the original shape and firmness of the distal curve. The catheter was then used to lead a guidewire to a sharply branching distal artery and subsequently to navigate itself into the artery. In each case, the angle formed by the vector of the proximal parent artery and that of the distal artery was measured to evaluate the technical difficulty. The usefulness of the catheter was assessed by whether stenting was completed. Results: The microcatheter was used in 10 cases. The average angle between the distal artery and the proximal parent artery was 144 ° . In two cases where the angle was over 180 ° , the guidewire could not enter the orifice of the distal artery directly. The guidewire could directly enter the orifice of the distal branch in eight cases, with angles of 108 ° –151 ° . In seven of the eight, the guidewire and microcatheter could go further into the distal artery, and stenting was achieved. Conclusion: A short and acutely angled catheter tip made from an Excelsior SL-10 pre-shaped S catheter with preservation of the distal curve is stable in shape. It is often useful when leading a guidewire to an artery branching at a sharp angle to prepare for stent-assisted coiling.
目的:描述了一种使用Excelsior SL-10预成形S型导管(Stryker, Kalamazoo, MI, USA)通过矫直其近端曲线来制作尖端短且锐角微导管的方法。介绍了其临床应用,其中导丝和微导管被引入远端动脉分支,以准备支架部署。方法:将导管的近端曲线插入一次性18号钝针中。用热风枪加热针头,只加热和拉直近端弯曲,保留远端弯曲的原始形状和牢固度。然后使用导管将导丝引导到一个急剧分支的远端动脉,随后引导自己进入动脉。在每种情况下,测量近端母动脉矢量与远端动脉矢量形成的角度以评估技术难度。通过支架植入是否完成来评估导管的有效性。结果:应用微导管治疗10例。远端动脉与近端载动脉的平均夹角为144°。在两例角度超过180°的情况下,导丝不能直接进入远端动脉口。8例导丝可直接进入远端分支孔内,角度为108°~ 151°。在8例患者中,有7例导丝和微导管可以进一步进入远端动脉,并且支架植入术成功。结论:用Excelsior SL-10预成形S型导管制成的短而尖锐角度的导管尖端保存了远端弯曲,形状稳定。当导丝以一个尖锐的角度引导动脉分支为支架辅助盘绕做准备时,它通常是有用的。
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引用次数: 1
Histological Examination of Thrombi in Patients with Cerebral Infarction in Embolic Stroke of Undetermined Source 来源不明的栓塞性脑梗死患者血栓的组织学检查
Pub Date : 2019-01-01 DOI: 10.5797/JNET.OA.2019-0015
Takehiro Katano, Genki Usui, Hirotsugu Hashimoto, T. Morikawa, S. Okubo, A. Ishii, S. Miyamoto, K. Kimura
Objective: We pathologically examined thrombi collected by mechanical thrombectomy in Embolic Stroke of Undetermined Source (ESUS). Methods: We examined the thrombi of acute ischemic stroke patients who underwent mechanical thrombectomy from January 2017 to June 2018. We histopathologically investigated the thrombi in ESUS patients, and performed a comparison with the thrombi of cardioembolic stroke. Results: Mechanical thrombectomy was performed in 35 patients, and the thrombus were obtained from five patients diagnosed as ESUS. The thrombus in one patient consisted of neutrophils and nuclear crush cells not only the red blood cells, and another one was included atheroma which was different from the typical clot in one patient. In the 25 cardioembolic stroke patients in this study, the thrombi were all constructed of fibrin, red blood cells, and platelets. Conclusion: In this pathological study, a difference was recognized in the clot components of ESUS. The results suggest that a pathological examination of thrombi obtained by mechanical thrombectomy is useful because there is a possibility that we can recognize the etiology of ESUS, and choose the best treatment for prevention of recurrence of stroke.
目的:对不明来源栓塞性脑卒中(ESUS)机械取栓术采集的血栓进行病理检查。方法:对2017年1月至2018年6月行机械取栓术的急性缺血性脑卒中患者的血栓进行检测。我们对ESUS患者的血栓进行了组织病理学研究,并与心源性卒中的血栓进行了比较。结果:35例患者行机械取栓术,其中5例诊断为ESUS患者取栓。1例患者的血栓不仅包括红细胞,还包括中性粒细胞和核粉碎细胞,另1例患者的血栓包括与典型血栓不同的动脉粥样硬化。在本研究的25例心源性卒中患者中,血栓均由纤维蛋白、红细胞和血小板构成。结论:在病理研究中,ESUS的凝块成分存在差异。结果提示,通过机械取栓获得的血栓病理检查是有用的,因为我们有可能识别ESUS的病因,并选择最佳的治疗方法来预防卒中复发。
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引用次数: 1
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