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A Patient with Hyperperfusion-related Cerebral Hemorrhage after Neuroendovascular Treatment for Vertebral Artery Stenosis 椎动脉狭窄神经血管内治疗后发生高灌注相关性脑出血1例
Pub Date : 2019-01-01 DOI: 10.5797/JNET.CR.2018-0014
K. Maeda, T. Ochi, Yoshiaki Goto, K. Arisawa, Shouhei Nanbu
Objective: We report a patient with hyperperfusion-related cerebral hemorrhage after neuroendovascular treatment for symptomatic vertebral artery stenosis. Case Presentation: The patient was a 75-year-old male, who presented with repeated attacks of vertigo. He was diagnosed with vertebral-basilar insufficiency. Subsequently, medical treatment involving the administration of an antiplatelet drug was performed, but brainstem infarction developed. Cerebral angiography showed occlusion of the left vertebral artery and stenosis at the origin and intracranial area of the right vertebral artery. Cerebral blood flow scintigraphy revealed a reduction in cerebellar blood flow as well as the site of infarction. The patient was considered to be resistant to medical treatment, and angioplasty was performed at two stenotic sites of the left vertebral artery. Despite strict blood pressure control, brainstem hemorrhage occurred 4 hours after surgery. The postoperative cerebral blood flow scintigraphy findings suggested hyperperfusion-related hemorrhage. Conclusion: For endovascular treatment of vertebral artery stenosis with cerebral blood flow failure, postoperative hyperperfusion-related cerebral hemorrhage may not be prevented by blood pressure control alone. Therapeutic strategies, such as a staged angioplasty, should be established based on cerebral blood flow examination findings.
目的:我们报告一例因症状性椎动脉狭窄接受神经血管内治疗后出现高灌注相关性脑出血的患者。病例介绍:患者男性,75岁,反复出现眩晕发作。他被诊断为椎基底动脉功能不全。随后,进行了包括抗血小板药物管理在内的医学治疗,但发展为脑干梗死。脑血管造影显示左侧椎动脉闭塞,右侧椎动脉起始及颅内狭窄。脑血流显像显示小脑血流减少以及梗死部位。患者被认为对药物治疗有抵抗力,并在左椎动脉的两个狭窄部位进行血管成形术。尽管严格控制血压,术后4小时仍发生脑干出血。术后脑血流显像提示高灌注相关出血。结论:对于椎动脉狭窄合并脑血流衰竭的血管内治疗,单纯控制血压可能无法预防术后高灌注相关性脑出血。治疗策略,如分阶段血管成形术,应根据脑血流检查结果确定。
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引用次数: 1
Use of Direct Carotid Artery Puncture Access for Flow Diverter Embolization Combined with Coil Embolization: A Case Report 颈动脉直接穿刺入路用于分流器栓塞联合线圈栓塞:1例报告
Pub Date : 2019-01-01 DOI: 10.5797/JNET.CR.2018-0109
Y. Funakoshi, T. Hatano, M. Ando, H. Chihara, W. Takita, K. Tokunaga, Takuro Hashikawa, T. Kamata, Eiji Higashi, I. Nagata
Objective: The fl ow diverter (FD) was developed as a new approach for treating aneurysms. However, FD embolization requires high technical skills and is challenging when the access to the aneurysm is diffi cult and when suffi cient force cannot be transmitted to the catheter because of severe vascular tortuosity. For FD embolization, when a transfemoral approach is too diffi cult, we perform direct puncture of the common carotid artery (CCA) under direct visualization by making a small incision. Herein, we report our experience using this approach. Case Presentation: We present a case of an 80-year-old woman with an unruptured aneurysm on the right internal carotid artery (ICA) treated by FD embolization in conjunction with coil embolization. We considered that access to the aneurysm would be challenging, with limited catheter maneuverability because of severe tortuosity of the bilateral femoral arteries and the region from the right CCA to the ICA. Thus, we decided to access the aneurysm by direct puncture of the right CCA. The aneurysm was easily accessed using this approach, and a stable procedure was completed by placing a sheath with a detachable hemostasis valve and then switching the hemostasis valve to a Y-connector on the sheath. As good catheter control was obtained despite the vascular tortuosity, the Pipeline Flex could be deployed and placed at the appropriate position. Conclusion: Direct puncture of the CCA under direct visualization for FD embolization is useful when access to the aneurysm is challenging and when catheter maneuverability decreases because of severe tortuosity.
目的:血流分流器(FD)是治疗动脉瘤的新方法。然而,FD栓塞需要较高的技术技能,当动脉瘤进入困难,且由于严重的血管扭曲无法将足够的力传递到导管时,FD栓塞具有挑战性。对于FD栓塞,当经股入路太困难时,我们通过做一个小切口在直接可见下直接穿刺颈总动脉(CCA)。在此,我们报告使用此方法的经验。病例介绍:我们报告了一例80岁的女性右颈内动脉(ICA)未破裂动脉瘤,采用FD栓塞联合线圈栓塞治疗。我们认为,由于双侧股动脉和右侧CCA到ICA的区域严重扭曲,导管可操作性有限,因此进入动脉瘤将是具有挑战性的。因此,我们决定通过直接穿刺右侧CCA进入动脉瘤。使用这种方法可以很容易地进入动脉瘤,并通过放置带有可拆卸止血阀的护套,然后将止血阀切换到护套上的y型连接器,完成了稳定的手术。尽管血管扭曲,但由于导管控制良好,因此可以将Pipeline Flex展开并放置在适当的位置。结论:在直视下直接穿刺CCA进行FD栓塞是有效的,当进入动脉瘤有困难时,当导管因严重扭曲而可操作性降低时。
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引用次数: 0
A Case of Transverse-sigmoid Sinus Dural Arteriovenous Fistula Treated by Transarterial and Transvenous Embolization via the Balloon Microcatheter with Overinflated Balloon Protection of the Torcula 球囊微导管经动、静脉栓塞治疗横乙状窦硬膜动静脉瘘1例,球囊过度充气保护小圆管
Pub Date : 2019-01-01 DOI: 10.5797/JNET.CR.2018-0103
Hajime Yabuzaki, T. Terada, H. Ikeda, M. Kawamo, A. Wada, S. Nakayama, Tomomi Yoshiyama, Eisuke Hirose, Yuuta Kawauchi, Y. Yamaguchi
Objective: The objectives of treating dural arteriovenous fistula (dAVF) are to achieve complete occlusion of the arteriovenous (AV) shunt and restoration of anterograde venous flow. We report a patient with complex dAVF who was managed by double overinflated balloon protection of the torcula and percutaneous transluminal angioplasty (PTA) for the occluded venous sinus. Case Presentation: A 62-year-old woman was admitted with gradually worsening nausea and vomiting, as well as progressive memory disturbance and left hemiparesis. Head MRI/MRA demonstrated a dAVF involving the region from the right sigmoid sinus (SS) to transverse sinus (TS) along with occlusion of the left TS and right proximal SS. There was associated dilatation of the right TS, torcula, and superior sagittal sinus (SSS). The intracranial venous circulation was impaired, with venous reflux draining into the deep cerebral veins as well as the cortical veins. Transarterial embolization (TAE) and transvenous embolization (TVE) were performed with double overinflated balloon protection of the torcula, and shunt flow was completely abolished. The occluded sinus was recanalized by PTA. Her symptoms gradually improved after treatment. Conclusion: In this patient, double overinflated balloon protection was effective for maintaining the torcula.
目的:硬脑膜动静脉瘘(dAVF)的治疗目的是完全阻断动静脉(AV)分流,恢复顺行静脉流动。我们报告了一位复杂的dAVF患者,他通过双重过度充气球囊保护环和经皮腔内血管成形术(PTA)治疗闭塞的静脉窦。病例介绍:一名62岁女性因逐渐加重的恶心和呕吐,以及进行性记忆障碍和左偏瘫入院。头部MRI/MRA显示dAVF累及右乙状窦(SS)至横窦(TS)区域,伴左侧TS和右侧SS近端闭塞。右侧TS、圆环和上矢状窦(SSS)伴有扩张。颅内静脉循环受损,静脉回流至脑深部静脉和皮质静脉。经动脉栓塞术(TAE)和经静脉栓塞术(TVE)采用双过气球囊保护环,完全消除分流血流。闭塞的鼻窦经PTA再通。治疗后症状逐渐好转。结论:双充气球囊保护对维持血管环是有效的。
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引用次数: 3
Carotid Stent Fracture due to Eagle Syndrome after Endovascular Stenting for the Treatment of Acute Ischemic Stroke Caused by Internal Carotid Artery Dissection: Case Report 血管内支架置入治疗颈内动脉夹层所致急性缺血性卒中后发生Eagle综合征颈动脉支架断裂1例
Pub Date : 2019-01-01 DOI: 10.5797/jnet.cr.2019-0032
T. Yano, I. Sasaki, Kanako Kiyohara, M. Kawanishi
Objective: We report a case of stent fracture caused by an elongated styloid process, a form of Eagle syndrome. Case Presentation: A 58-year-old man presented with sudden right hemisensation disturbance and aphasia. MRI revealed multiple acute cerebral infarction in the left parietal and insula cortex. MRA revealed a left-sided internal carotid artery (ICA) occlusion distal to the carotid bifurcation. Digital subtraction angiography (DSA) revealed a left-sided ICA dissection distal to the carotid bifurcation. We performed acute revascularization with aspiration of the thrombus and stenting to treat the carotid dissection. Recanalization with thrombolysis in cerebral infarction (TICI) grade III was achieved. We performed DSA 3 months after an operation, it showed stent fracture and aneurysmal formation in the stent fractured department. From CT findings, the carotid artery dissection and stent fracture appeared to be triggered by the elongated styloid process. We performed stent-assisted coil embolization. After conducting percutaneous transluminal angioplasty (PTA) at high pressure after coil embolization, the elongated styloid process was fractured, and accepted a shift to the outside of the stent contact department. The patient was discharged without medical problems, and no recurrence was observed for 2 months after the surgery. Conclusion: We experienced a rare case of ICA dissection and carotid stent fracture from Eagle syndrome. Eagle syndrome is an important disease to consider in the differential diagnosis of extracranial carotid artery dissection.
目的:我们报告一例由茎突拉长引起的支架骨折,这是鹰综合征的一种形式。病例介绍:一名58岁男性,表现为突发性右半球感觉障碍和失语。MRI显示左顶叶及脑岛皮层多发急性脑梗死。MRA显示左侧颈内动脉(ICA)闭塞远颈动脉分叉。数字减影血管造影(DSA)显示颈动脉分叉远端左侧ICA夹层。我们进行了急性血运重建术,血栓抽吸和支架置入治疗颈动脉夹层。在III级脑梗死(TICI)中实现了溶栓再通。术后3个月行DSA检查,发现支架骨折部有支架断裂及动脉瘤形成。从CT表现来看,颈动脉剥离和支架断裂似乎是由茎突延长引发的。我们进行了支架辅助线圈栓塞。在线圈栓塞后进行高压经皮腔内血管成形术(PTA)后,延长的茎突断裂,并接受转移到支架接触部外。患者出院无内科问题,术后2个月无复发。结论:我们经历了一例罕见的Eagle综合征颈动脉内动脉夹层和颈动脉支架断裂。Eagle综合征是颅外颈动脉夹层鉴别诊断中需要考虑的重要疾病。
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引用次数: 4
Usefulness of Preoperative Transarterial Feeder Embolization of Cerebellar Hemangioblastomas 术前经动脉喂食器栓塞治疗小脑血管母细胞瘤的有效性
Pub Date : 2019-01-01 DOI: 10.5797/jnet.oa.2018-0021
T. Kinoshita, Yusuke Egashira, Naoya Imai, Y. Enomoto, N. Nakayama, H. Yano, S. Yoshimura, T. Iwama
Objective: Preoperative transarterial feeder embolization (TAE) may contribute to the safe surgical removal of hyper­ vascular tumors such as cerebellar hemangioblastomas (CHBs). We examined the usefulness of preoperative TAE of CHBs in our series. Methods: We retrospectively analyzed the results of treatment in seven patients with CHBs who had undergone preoperative TAE and subsequent surgery in our hospital between 2005 and 2015 (four males and three females, mean age: 45 years). Results: The embolized feeders consisted of the posterior inferior cerebellar artery in five patients, superior cerebellar artery (SCA) in one patient, and occipital artery (OA) in one patient. The embolic materials consisted of polyvinyl alcohol (PVA) in two patients, n­butyl­2­cyanoacrylate (NBCA) in four patients, and the combination of PVA and NBCA in one patient. Surgery was performed 1–4 days after embolization. The mean volume of intraoperative blood loss was 593 mL. In all patients, total surgical removal of the tumor was possible in the absence of non­autologous blood transfusion. Furthermore, embolic blood vessels could be identified during surgery in all patients, contributing to intraoperative orientation. Periprocedural complication related to TAE, cerebellar infarction related to embolic­material migration into a normal blood vessel occurred in one patient (13%). Conclusion: The results suggest that preoperative TAE of CHBs using NBCA contributes to a decrease in the volume of intraoperative blood loss, intraoperative orientation, and safe surgical removal of CHBs.
目的:术前经动脉喂食器栓塞(TAE)可能有助于小脑血管母细胞瘤(CHBs)等高血管肿瘤的安全手术切除。在我们的系列研究中,我们检查了CHBs术前TAE的有效性。方法:回顾性分析我院2005 - 2015年间行术前TAE及术后手术的7例CHBs患者(男4例,女3例,平均年龄45岁)的治疗结果。结果:5例为小脑后下动脉栓塞,1例为小脑上动脉栓塞,1例为枕动脉栓塞。栓塞材料包括2例聚乙烯醇(PVA), 4例正丁基- 2 -氰基丙烯酸酯(NBCA), 1例PVA和NBCA联合使用。栓塞后1-4天进行手术。术中平均失血量为593 mL。所有患者均可在无非自体输血的情况下手术切除肿瘤。此外,所有患者在手术过程中均可识别栓塞血管,有助于术中定位。1例(13%)患者发生与TAE相关的围手术期并发症,栓塞物质迁移到正常血管相关的小脑梗死。结论:术前应用NBCA对CHBs进行TAE有助于减少术中出血量,降低术中定向,安全切除CHBs。
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引用次数: 0
Cerebral Vasospasm and Patient Outcome after Coiling or Clipping for Intracranial Aneurysmal Subarachnoid Hemorrhage 颅内动脉瘤性蛛网膜下腔出血卷取或夹持后脑血管痉挛与患者预后
Pub Date : 2019-01-01 DOI: 10.5797/jnet.oa.2019-0023
Kentaro Shimoda, K. Kamiya, T. Kano, M. Furuichi, A. Yoshino
Objective: It is still controversial whether coiling or clipping has a lower incidence of cerebral vasospasm following an aneurysmal subarachnoid hemorrhage (SAH). In this study, we compared angiographic vasospasm (AV), symptomatic vasospasm (SV), and the outcome of both procedures for ruptured cerebral aneurysms. Methods: From 2007 to 2018, 127 patients were coiled and 127 were clipped for ruptured cerebral aneurysms. We retrospectively reviewed AV, SV, and the outcome of both procedures. Results: The incidence of AV was 32 (25%) patients for coiling and 59 (46%) patients for clipping. SV occurred in eight (6%) patients for coiling and 19 (15%) patients for clipping, and was significantly less in the coiling group. A favorable outcome (modified Rankin scale [mRS] 0-2 on discharge) was in 71 (56%) patients for coiling and 77 (61%) patients for clipping, and there was no significant difference between the two groups. Conclusion: The incidence of SV was significantly less in the coiling group for ruptured cerebral aneurysms. Even if SV occurred following aneurysmal SAH, early therapeutic intervention may prevent deterioration of the outcome.
目的:动脉瘤性蛛网膜下腔出血(SAH)后脑血管痉挛的发生率是否较低仍存在争议。在这项研究中,我们比较了血管造影血管痉挛(AV)、症状性血管痉挛(SV)以及两种手术治疗脑动脉瘤破裂的结果。方法:2007年至2018年,对127例脑动脉瘤破裂患者行螺旋治疗,127例行夹持治疗。我们回顾性地回顾了AV、SV和两种手术的结果。结果:卷取组AV发生率为32例(25%),夹取组AV发生率为59例(46%)。卷取组有8例(6%)患者发生SV,夹取组有19例(15%)患者发生SV,卷取组明显较少。卷取组71例(56%)、夹取组77例(61%)预后良好(出院时改良Rankin量表[mRS] 0-2),两组比较无显著差异。结论:脑动脉瘤破裂后,卷取组SV发生率明显降低。即使SV发生在动脉瘤性SAH之后,早期治疗干预也可以防止结果恶化。
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引用次数: 1
Continuous Educational Interventions Help Emergency Medical Services Effectively Reduce the Therapeutic Time in Acute Ischemic Stroke 持续教育干预有助于急诊医疗服务有效缩短急性缺血性卒中的治疗时间
Pub Date : 2019-01-01 DOI: 10.5797/jnet.oa.2019-0073
Manoj Bohara, Y. Nishimuta, Y. Sadamura, Dan Kawahara, Soichiro Komasaku, Masanao Mori, M. Yamada, H. Tokimura, K. Yoshimoto
Background: Early recognition of stroke symptoms, pre-notification to the hospital, and rapid transport of the patients has been associated with faster intervention and better outcomes. We studied the impact of continuous monthly educational intervention to the emergency medical services (EMS) members on the therapeutic time till mechanical thrombectomy in acute ischemic stroke. Methods: Our hospital manages Doctor Heli (DH) and Doctor Car (DC). Since April 2017, continuous monthly educational sessions on stroke care have been conducted involving the EMS doctors and paramedics, using the modalities like lectures and focus group discussions. We evaluated the change in performance time indicators prior to and after the initiation of this educational intervention. Results: In all, 10 patients underwent mechanical thrombectomy for acute ischemic stroke before and 36 patients underwent the procedure after the initiation of educational intervention program. The number of EMS-transported patients (by DH and DC) out of the total patients who underwent mechanical thrombectomy increased from 20% to 42% after the initiation of the educational intervention. The median time interval of onset to door (O2D) decreased from 109.5 to 71 minutes and that of door to recanalization (D2R) decreased from 164 to 88 minutes following the educational intervention. Other performance time indicators were also notably reduced. This improvement of time indicators was observed gradually and annually. Conclusion: This study showed that the continuous monthly education on stroke care to EMS members notably increased the number of EMS-transported patients as well as improved the performance time indicators till treatment in acute ischemic stroke.
背景:早期识别脑卒中症状,提前通知医院,快速运送患者与更快的干预和更好的结果相关。我们研究了急诊医疗服务(EMS)成员持续每月教育干预对急性缺血性脑卒中机械取栓治疗时间的影响。方法:我院对Heli医生(DH)和Car医生(DC)进行管理。自2017年4月起,通过讲座和焦点小组讨论等方式,持续每月举办一次由急救医生和护理人员参加的中风护理教育课程。我们评估了在这种教育干预开始之前和之后表现时间指标的变化。结果:10例急性缺血性脑卒中患者在教育干预计划启动前接受机械取栓,36例患者在教育干预计划启动后接受机械取栓。在教育干预开始后,接受机械取栓的患者中ems转运患者(由DH和DC转运)的数量从20%增加到42%。教育干预后,患者从发病到门的中位时间间隔(O2D)从109.5分钟减少到71分钟,从门到再通的中位时间间隔(D2R)从164分钟减少到88分钟。其他性能时间指标也显著降低。这种时间指标的改善是逐年逐步观察到的。结论:本研究表明,持续每月对EMS成员进行卒中护理教育,可显著增加EMS转运患者的数量,改善急性缺血性卒中治疗的绩效时间指标。
{"title":"Continuous Educational Interventions Help Emergency Medical Services Effectively Reduce the Therapeutic Time in Acute Ischemic Stroke","authors":"Manoj Bohara, Y. Nishimuta, Y. Sadamura, Dan Kawahara, Soichiro Komasaku, Masanao Mori, M. Yamada, H. Tokimura, K. Yoshimoto","doi":"10.5797/jnet.oa.2019-0073","DOIUrl":"https://doi.org/10.5797/jnet.oa.2019-0073","url":null,"abstract":"Background: Early recognition of stroke symptoms, pre-notification to the hospital, and rapid transport of the patients has been associated with faster intervention and better outcomes. We studied the impact of continuous monthly educational intervention to the emergency medical services (EMS) members on the therapeutic time till mechanical thrombectomy in acute ischemic stroke. Methods: Our hospital manages Doctor Heli (DH) and Doctor Car (DC). Since April 2017, continuous monthly educational sessions on stroke care have been conducted involving the EMS doctors and paramedics, using the modalities like lectures and focus group discussions. We evaluated the change in performance time indicators prior to and after the initiation of this educational intervention. Results: In all, 10 patients underwent mechanical thrombectomy for acute ischemic stroke before and 36 patients underwent the procedure after the initiation of educational intervention program. The number of EMS-transported patients (by DH and DC) out of the total patients who underwent mechanical thrombectomy increased from 20% to 42% after the initiation of the educational intervention. The median time interval of onset to door (O2D) decreased from 109.5 to 71 minutes and that of door to recanalization (D2R) decreased from 164 to 88 minutes following the educational intervention. Other performance time indicators were also notably reduced. This improvement of time indicators was observed gradually and annually. Conclusion: This study showed that the continuous monthly education on stroke care to EMS members notably increased the number of EMS-transported patients as well as improved the performance time indicators till treatment in acute ischemic stroke.","PeriodicalId":34768,"journal":{"name":"JNET","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71058701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Verification of the Availability of Cerulean DD6 验证天蓝色DD6的可用性
Pub Date : 2019-01-01 DOI: 10.5797/jnet.oa.2019-0031
Keisuke Sato, Yasushi Ito, H. Hasegawa, Tsutomu Kobayashi, H. Aoki, Shinya Jinguji, Y. Fujii
Objective: We show our experiences with the use of a 6Fr Cerulean DD6 (Medikit, Tokyo, Japan) catheter and represent the availability of DD6. Methods: Between May 2017 and October 2018, we performed 19 neurointerventional procedures for 17 patients of anterior circulation aneurysms and two neurointerventional procedures for two patients of posterior circulation aneurysms. We validated the results of the procedures with DD6 such as the techniques of coil embolization, the positions of DD6, the related complications, the kickbacks of DD6, and so on. Results: In all cases, we succeeded with the placement of DD6 and there were no related complications and kickbacks of DD6. The positions of DD6 were C3 in six cases, C4 in 8, C5 in 5, V3 in 1, and V4 in 1. Of all procedures, 12 were performed with the balloon assist technique, 5 were with the stent assist technique, and 4 were with the simple technique. Conclusion: Utilizing DD6, the access difficulty of cervical vessels is apparently reduced and the maneuvers of microcatheters can be made much safer and more reliable for neurointerventional procedures.
目的:我们展示我们使用6Fr Cerulean DD6 (Medikit,东京,日本)导管的经验,并代表DD6的可用性。方法:2017年5月至2018年10月,我们对17例前循环动脉瘤患者进行了19例神经介入手术,对2例后循环动脉瘤患者进行了2例神经介入手术。我们对DD6的手术结果进行了验证,如线圈栓塞技术、DD6的位置、相关并发症、DD6的回扣等。结果:所有病例均成功置入DD6,无DD6相关并发症及回扣。DD6位置依次为C3 6例,C4 8例,C5 5例,V3 1例,V4 1例。12例采用球囊辅助技术,5例采用支架辅助技术,4例采用简单技术。结论:使用DD6可明显降低颈椎血管的通路难度,使微导管在神经介入手术中的操作更加安全可靠。
{"title":"Verification of the Availability of Cerulean DD6","authors":"Keisuke Sato, Yasushi Ito, H. Hasegawa, Tsutomu Kobayashi, H. Aoki, Shinya Jinguji, Y. Fujii","doi":"10.5797/jnet.oa.2019-0031","DOIUrl":"https://doi.org/10.5797/jnet.oa.2019-0031","url":null,"abstract":"Objective: We show our experiences with the use of a 6Fr Cerulean DD6 (Medikit, Tokyo, Japan) catheter and represent the availability of DD6. Methods: Between May 2017 and October 2018, we performed 19 neurointerventional procedures for 17 patients of anterior circulation aneurysms and two neurointerventional procedures for two patients of posterior circulation aneurysms. We validated the results of the procedures with DD6 such as the techniques of coil embolization, the positions of DD6, the related complications, the kickbacks of DD6, and so on. Results: In all cases, we succeeded with the placement of DD6 and there were no related complications and kickbacks of DD6. The positions of DD6 were C3 in six cases, C4 in 8, C5 in 5, V3 in 1, and V4 in 1. Of all procedures, 12 were performed with the balloon assist technique, 5 were with the stent assist technique, and 4 were with the simple technique. Conclusion: Utilizing DD6, the access difficulty of cervical vessels is apparently reduced and the maneuvers of microcatheters can be made much safer and more reliable for neurointerventional procedures.","PeriodicalId":34768,"journal":{"name":"JNET","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71059154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Internal Trapping of a Symptomatic Unruptured Giant Vertebral Artery Aneurysm Using the Coiling-in-bridging-stent Technique: A Case Report 用桥内支架技术圈闭有症状的未破裂巨大椎动脉动脉瘤1例报告
Pub Date : 2019-01-01 DOI: 10.5797/JNET.CR.2018-0076
Osamu Ishikawa, K. Tsutsumi, M. Shojima, Gakushi Yoshikawa, A. Saito, Sho Tsunoda, Katsuya Sato, Takaki Omura, N. Saito
Objective: We report a patient in whom a devised stent-assisted internal trapping was effective to eliminate the mass effect of a symptomatic giant vertebral artery (VA) aneurysm. Case Presentation: A 63-year-old female. Detailed examination of gait disorder showed a brainstem-compressing, nonthrombotic, giant, fusiform aneurysm at an area distal to the posterior inferior cerebellar artery (PICA) bifurcation of the left VA. Endovascular internal trapping was planned, but the exacerbation of mass effects related to the coils inserted into the aneurysm cavity was concerned. Thus, before the usual internal trapping procedure, a self-expanding stent was deployed across the aneurysm to limit the coils in the stent during the internal trapping procedure. Six months later, the aneurysm decreased markedly in size with a complete relief of neurological symptom. Conclusion: Our devised stent-assisted internal trapping method, coiling-in bridging-stent technique, was successful to exclude a symptomatic giant VA aneurysm from the circulation with a minimum amount of coil in the aneurysm cavity. With this method, marked decrease in size could be expected since coils would not interfere with the shrinkage of the aneurysm. This method would be useful in giant cerebral aneurysms which need endovascular internal trapping.
目的:我们报告了一位病人,他设计了支架辅助的内夹有效地消除了有症状的椎巨动脉(VA)动脉瘤的肿块效应。病例介绍:63岁女性。步态障碍的详细检查显示,在左心室后下小脑动脉(PICA)分支远端区域有一个脑干压迫性、非血栓性、巨大的梭状动脉瘤。计划进行血管内捕获,但担心与插入动脉瘤腔的线圈相关的肿块效应加剧。因此,在通常的内部捕获程序之前,在动脉瘤上部署一个自膨胀支架,以限制支架在内部捕获过程中的线圈。6个月后,动脉瘤大小明显减小,神经症状完全缓解。结论:我们设计的支架辅助内捕获方法,即线圈内桥式支架技术,成功地将有症状的巨大VA动脉瘤从循环中排除,动脉瘤腔内的线圈最少。使用这种方法,由于线圈不会干扰动脉瘤的收缩,因此可以预期尺寸显着减小。该方法适用于需要血管内夹闭的巨大脑动脉瘤。
{"title":"Internal Trapping of a Symptomatic Unruptured Giant Vertebral Artery Aneurysm Using the Coiling-in-bridging-stent Technique: A Case Report","authors":"Osamu Ishikawa, K. Tsutsumi, M. Shojima, Gakushi Yoshikawa, A. Saito, Sho Tsunoda, Katsuya Sato, Takaki Omura, N. Saito","doi":"10.5797/JNET.CR.2018-0076","DOIUrl":"https://doi.org/10.5797/JNET.CR.2018-0076","url":null,"abstract":"Objective: We report a patient in whom a devised stent-assisted internal trapping was effective to eliminate the mass effect of a symptomatic giant vertebral artery (VA) aneurysm. Case Presentation: A 63-year-old female. Detailed examination of gait disorder showed a brainstem-compressing, nonthrombotic, giant, fusiform aneurysm at an area distal to the posterior inferior cerebellar artery (PICA) bifurcation of the left VA. Endovascular internal trapping was planned, but the exacerbation of mass effects related to the coils inserted into the aneurysm cavity was concerned. Thus, before the usual internal trapping procedure, a self-expanding stent was deployed across the aneurysm to limit the coils in the stent during the internal trapping procedure. Six months later, the aneurysm decreased markedly in size with a complete relief of neurological symptom. Conclusion: Our devised stent-assisted internal trapping method, coiling-in bridging-stent technique, was successful to exclude a symptomatic giant VA aneurysm from the circulation with a minimum amount of coil in the aneurysm cavity. With this method, marked decrease in size could be expected since coils would not interfere with the shrinkage of the aneurysm. This method would be useful in giant cerebral aneurysms which need endovascular internal trapping.","PeriodicalId":34768,"journal":{"name":"JNET","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71055949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Preliminary Experience of Preoperative Modification of Platelet Aggregation 术前血小板聚集调节的初步体会
Pub Date : 2019-01-01 DOI: 10.5797/JNET.OA.2018-0078
T. Kanamaru, S. Yoshimura, Toshinori Takagi, Mikiya Beppu, K. Kimura
Objective: Antiplatelet drugs are frequently used to prevent ischemic complications of endovascular therapy, but patients who showed poor responses to these drugs have been reported. We have adjusted antiplatelet drugs based on platelet aggregation activity before endovascular therapy. The objective of this study was to investigate the association between platelet aggregation test-based modification of antiplatelet drugs and perioperative complications. Methods: In this study, we enrolled 146 patients who received elective endovascular therapy between October 2015 and December 2016. All patients received administration of aspirin 100 mg and clopidogrel 75 mg from 2 weeks before endovascular therapy and platelet aggregation activity was measured 1–2 days before the procedure. Cilostazol was additionally administered to patients who poorly responded to aspirin, or the drug was switched to prasugrel in patients who poorly responded to clopidogrel. Thereafter, platelet aggregation activity was re-tested on the following morning. Results: On the initial test, 52 (35.6%) and 57 (39.0%) patients showed poor responses to aspirin and clopidogrel, respectively, and these rates were higher than those previously reported. After antiplatelet drug modification, 31 (21.2%) and 20 (13.7%) patients showed poor responses to aspirin and clopidogrel, respectively, showing significant decreases (p = 0.012 and <0.0001, respectively). Perioperative ischemic complication developed in five patients (3.4%), being lower than that (4.6%) previously reported. Conclusion: The rate of patients with poor responses to antiplatelet drugs on the platelet aggregation test was higher than those previously reported, but their responses were improved by drug modification. Platelet aggregation test-based drug modification may be effective to prevent perioperative complications and further investigation is necessary.
目的:抗血小板药物常用于预防血管内治疗的缺血性并发症,但有报道称患者对这些药物反应不佳。我们在血管内治疗前根据血小板聚集活性调整抗血小板药物。本研究的目的是探讨基于血小板聚集试验的抗血小板药物修饰与围手术期并发症的关系。方法:在本研究中,我们纳入了2015年10月至2016年12月期间接受选择性血管内治疗的146例患者。所有患者在血管内治疗前2周开始给予阿司匹林100 mg和氯吡格雷75 mg,并在手术前1-2天测量血小板聚集活性。对阿司匹林反应不良的患者额外使用西洛他唑,或对氯吡格雷反应不良的患者改用普拉格雷。随后,第二天早上再次检测血小板聚集活性。结果:在初始试验中,分别有52例(35.6%)和57例(39.0%)患者对阿司匹林和氯吡格雷反应不良,这一比例高于先前报道。经抗血小板药物修饰后,阿司匹林不良反应31例(21.2%),氯吡格雷不良反应20例(13.7%),均有显著降低(p = 0.012, <0.0001)。5例患者出现围手术期缺血性并发症(3.4%),低于先前报道的4.6%。结论:抗血小板药物血小板聚集试验反应差的患者比例高于既往报道的患者,但经药物修饰可改善其反应。基于血小板聚集试验的药物修饰可能有效预防围手术期并发症,需要进一步研究。
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引用次数: 0
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