Yuliya F. Shumskaya, Dina A. Akhmedzyanova, Marina G. Mnatsakanyan, Ksenia Yu. Kolosova, Olga V. Tashchyаn, Marta V. Yurazh, Roman V. Reshetnikov
Background. Patients with inflammatory bowel disease (IBD) often require lifelong follow-up by a clinician. A promising area of such health care services is telemedicine monitoring, often based on the evaluation of patients' remote questionnaire results by a medical practitioner.
Aim. To define, using the Delphi method, a list of questionnaire-assessed parameters for use in the monitoring and treatment of patients with IBD.
Materials and Methods. The study was conducted in three stages. We created an electronic survey form to collect information, making sure that the respondent's experience was included when completing the survey. At the first stage, respondents answered an open-ended question about what parameters assessed by questionnaires should be monitored in patients with IBD. In the second stage, participants answered the same question, but selected any number of items from a list. In the third stage, we analyzed the responses. The primary endpoint was a consensus on each parameter, defined as 75% respondent agreement.
Results. There were 15 participants in the study, 13.3% of whom were male. 46% of respondents worked in an outpatient setting and 54% worked in an inpatient setting. The age range was from 25 to 53 years, with 53% of participants having 1 to 4 years of experience and 47% having 17 to 29 years of experience. None of the parameters reached a 75% agreement level based on the results of the first stage. At the second stage, respondents reached consensus on 72% of the parameters. We found no relationship between respondents' age, gender, years of experience, or job setting and responses in both the first and second stages.
Conclusions. The final list of parameters recommended for evaluation during monitoring and treatment of patients with IBD included: abdominal pain; frequency of defecation and stool quality; presence of pathological stool impurities; body temperature; joint/muscle pain; sleep quality; anxiety; depression; work capacity for employed/ability of attendance for students; energy, quantity of vigor; fixation on the disease; patients' general evaluation of their life quality; adherence to treatment.
{"title":"Delphi method to determine a list of questionnaire-assessed parameters in the follow-up of patients with inflammatory bowel disease.","authors":"Yuliya F. Shumskaya, Dina A. Akhmedzyanova, Marina G. Mnatsakanyan, Ksenia Yu. Kolosova, Olga V. Tashchyаn, Marta V. Yurazh, Roman V. Reshetnikov","doi":"10.17816/dd545997","DOIUrl":"https://doi.org/10.17816/dd545997","url":null,"abstract":"Background. Patients with inflammatory bowel disease (IBD) often require lifelong follow-up by a clinician. A promising area of such health care services is telemedicine monitoring, often based on the evaluation of patients' remote questionnaire results by a medical practitioner.
 Aim. To define, using the Delphi method, a list of questionnaire-assessed parameters for use in the monitoring and treatment of patients with IBD.
 Materials and Methods. The study was conducted in three stages. We created an electronic survey form to collect information, making sure that the respondent's experience was included when completing the survey. At the first stage, respondents answered an open-ended question about what parameters assessed by questionnaires should be monitored in patients with IBD. In the second stage, participants answered the same question, but selected any number of items from a list. In the third stage, we analyzed the responses. The primary endpoint was a consensus on each parameter, defined as 75% respondent agreement.
 Results. There were 15 participants in the study, 13.3% of whom were male. 46% of respondents worked in an outpatient setting and 54% worked in an inpatient setting. The age range was from 25 to 53 years, with 53% of participants having 1 to 4 years of experience and 47% having 17 to 29 years of experience. None of the parameters reached a 75% agreement level based on the results of the first stage. At the second stage, respondents reached consensus on 72% of the parameters. We found no relationship between respondents' age, gender, years of experience, or job setting and responses in both the first and second stages.
 Conclusions. The final list of parameters recommended for evaluation during monitoring and treatment of patients with IBD included: abdominal pain; frequency of defecation and stool quality; presence of pathological stool impurities; body temperature; joint/muscle pain; sleep quality; anxiety; depression; work capacity for employed/ability of attendance for students; energy, quantity of vigor; fixation on the disease; patients' general evaluation of their life quality; adherence to treatment.","PeriodicalId":34831,"journal":{"name":"Digital Diagnostics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134913594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sifia F. Ageeva, Daria A. Filatova, Elena A. Mershina, Valentin E. Sinitsyn
The "rice bodies" symptom on magnetic resonance imaging (MRI) of the shoulder joint in patients with rheumatoid arthritis (RA) is a rare but specific finding characterised by the presence of multiple small, round, rice-grain-like structures in the synovial fluid of the joint, synovial pouches or sheaths. The etiology of the "rice bodies" is still not fully understood. It has been suggested that they are the result of microinfarcts of the synovial membrane.
This article presents a clinical case of rice bodies symptom diagnosed by MRI in a patient with a long history of rheumatoid arthritis who presented with a painless increase in the left shoulder. The computes tomography (CT) and MRI scans of the left shoulder were able to detect the rice bodies symptom as a manifestation of the underlying disease.
{"title":"\"Rice-bodies\" symptom on magnetic resonance imaging of the shoulder in a patient with rheumatoid arthritis","authors":"Sifia F. Ageeva, Daria A. Filatova, Elena A. Mershina, Valentin E. Sinitsyn","doi":"10.17816/dd508786","DOIUrl":"https://doi.org/10.17816/dd508786","url":null,"abstract":"The \"rice bodies\" symptom on magnetic resonance imaging (MRI) of the shoulder joint in patients with rheumatoid arthritis (RA) is a rare but specific finding characterised by the presence of multiple small, round, rice-grain-like structures in the synovial fluid of the joint, synovial pouches or sheaths. The etiology of the \"rice bodies\" is still not fully understood. It has been suggested that they are the result of microinfarcts of the synovial membrane.
 This article presents a clinical case of rice bodies symptom diagnosed by MRI in a patient with a long history of rheumatoid arthritis who presented with a painless increase in the left shoulder. The computes tomography (CT) and MRI scans of the left shoulder were able to detect the rice bodies symptom as a manifestation of the underlying disease.","PeriodicalId":34831,"journal":{"name":"Digital Diagnostics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134913590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natalia G. Poteshkina, Elena A. Kovalevskaya, Valentin E. Sinitsyn, Elena A. Mershina, Daria A. Filatova, Galina B. Selivanova, Yavilika R. Shashkina
Myocarditis is often a difficult heart condition to diagnose. This article presents a clinical case of a young patient with symptoms of acute coronary syndrome who showed no evidence of coronary artery disease. Myocarditis was suspected due to elevated levels of cardiospecific enzymes and inflammatory markers, pronounced electrocardiography changes with positive dynamics, as well as the fact of a previous infection. The cardiac magnetic resonance imaging was used to confirm the diagnosis of myocarditis. Thus, the role of imaging techniques in the differential diagnosis of ischemic and inflammatory heart disease has been demonstrated.
{"title":"Difficulties in myocarditis diagnosis (clinical case)","authors":"Natalia G. Poteshkina, Elena A. Kovalevskaya, Valentin E. Sinitsyn, Elena A. Mershina, Daria A. Filatova, Galina B. Selivanova, Yavilika R. Shashkina","doi":"10.17816/dd546163","DOIUrl":"https://doi.org/10.17816/dd546163","url":null,"abstract":"Myocarditis is often a difficult heart condition to diagnose. This article presents a clinical case of a young patient with symptoms of acute coronary syndrome who showed no evidence of coronary artery disease. Myocarditis was suspected due to elevated levels of cardiospecific enzymes and inflammatory markers, pronounced electrocardiography changes with positive dynamics, as well as the fact of a previous infection. The cardiac magnetic resonance imaging was used to confirm the diagnosis of myocarditis. Thus, the role of imaging techniques in the differential diagnosis of ischemic and inflammatory heart disease has been demonstrated.","PeriodicalId":34831,"journal":{"name":"Digital Diagnostics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134913197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuriy A. Vasilev, O. Omelyanskaya, A. Vladzimirsky, P. Gelezhe, Roman V. Reshetnikov, A. Gonchar, Ivan A. Blokhin, Irina Kieva
Background: MRI can detect clinically significant prostate cancer, diagnose extracapsular extension and stage of the cancer. A scanning protocol including only T2-weighted and diffusion-weighted images represents a viable alternative to multiparametric MRI, provided that high diagnostic accuracy of the test is maintained. In recent studies, the diagnostic accuracy of bpMRI and mpMRI in detecting prostate cancer has demonstrated little difference. Objective: to compare the diagnostic accuracy of bpMRI and mpMRI for the detection of clinically significant prostate cancer using PI-RADS v2.1 with MRI-guided multifocal biopsy as the gold standard. Materials and methods: this study is retrospective. We initially processed the medical records of 126 patients. Inclusion criteria were the presence of a PI-RADS 2.1 mpMRI, clinical information on free and bound PSA blood levels, a multifocal prostate biopsy performed, and a time interval between MRI and biopsy of no more than 14 days. Three investigators (radiologists with less than 2 years' experience, 2 to 5 years' experience, and more than 5 years' experience) independently evaluated bpMRI of the prostate for the presence of pathological foci. After a period of 2 weeks, the researchers evaluated the dataset of mpMRI of the prostate. Each lesion detected, starting from PI-RADS category 3, was compared with the result of a multifocal fusion biopsy. The biopsy result was presented as a sum of Gleason scores, with a Gleason score of 7 or higher being considered clinically relevant biopsy findings. Findings meeting PI-RADS criteria 4 and 5 were considered as tumor foci according to MRI data. Conclusion: biparametric protocols of prostate MRI have a definite economic advantage over multiparametric protocols due to absence of costs for contrast media and significant decrease of MRI scanner loading time. Diagnostic accuracy of bpMRI to detect prostate foci is not inferior to mpMRI. At the same time, the use of DCE presumably allows reducing the number of biopsies.
{"title":"Comparison of multiparametric and biparametric magnetic resonance imaging protocols for prostate cancer diagnostics by radiologists with different experience","authors":"Yuriy A. Vasilev, O. Omelyanskaya, A. Vladzimirsky, P. Gelezhe, Roman V. Reshetnikov, A. Gonchar, Ivan A. Blokhin, Irina Kieva","doi":"10.17816/dd322816","DOIUrl":"https://doi.org/10.17816/dd322816","url":null,"abstract":"Background: MRI can detect clinically significant prostate cancer, diagnose extracapsular extension and stage of the cancer. A scanning protocol including only T2-weighted and diffusion-weighted images represents a viable alternative to multiparametric MRI, provided that high diagnostic accuracy of the test is maintained. In recent studies, the diagnostic accuracy of bpMRI and mpMRI in detecting prostate cancer has demonstrated little difference. \u0000Objective: to compare the diagnostic accuracy of bpMRI and mpMRI for the detection of clinically significant prostate cancer using PI-RADS v2.1 with MRI-guided multifocal biopsy as the gold standard. \u0000Materials and methods: this study is retrospective. We initially processed the medical records of 126 patients. Inclusion criteria were the presence of a PI-RADS 2.1 mpMRI, clinical information on free and bound PSA blood levels, a multifocal prostate biopsy performed, and a time interval between MRI and biopsy of no more than 14 days. Three investigators (radiologists with less than 2 years' experience, 2 to 5 years' experience, and more than 5 years' experience) independently evaluated bpMRI of the prostate for the presence of pathological foci. After a period of 2 weeks, the researchers evaluated the dataset of mpMRI of the prostate. Each lesion detected, starting from PI-RADS category 3, was compared with the result of a multifocal fusion biopsy. The biopsy result was presented as a sum of Gleason scores, with a Gleason score of 7 or higher being considered clinically relevant biopsy findings. Findings meeting PI-RADS criteria 4 and 5 were considered as tumor foci according to MRI data. \u0000Conclusion: biparametric protocols of prostate MRI have a definite economic advantage over multiparametric protocols due to absence of costs for contrast media and significant decrease of MRI scanner loading time. Diagnostic accuracy of bpMRI to detect prostate foci is not inferior to mpMRI. At the same time, the use of DCE presumably allows reducing the number of biopsies.","PeriodicalId":34831,"journal":{"name":"Digital Diagnostics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43524514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Berezovskaya, A. Rubtsova, alentin E. Sinitsyn, V. Irina, Zarodnyuk, Nicolai V. Nudnov, Andrei V. Mishchenko, Yuliya L. Trubacheva, A. Bergen, Pavel, U. Grishko, Svetlana S. Balyasnikova, A. Dayneko, M. Malika, odzhibekova, Nataliya A. Rucheva, Igor E. Turin, I. Sergey, Achkasov, A. A. Nevolskikh, Sergey S. Gordeev, .. Droshneva
Backgraund. Unified terminology is a necessary condition for successful interdisciplinary communication in oncology. The variety of anatomical, pathomorphological and clinical terms used in rectal cancer (RC) is often accompanied by their ambiguous interpretation both in domestic and foreign scientific literature. This not only complicates the interaction between specialists, but also makes it difficult to compare the results of RC treatment obtained in different medical institutions. Aim. Develop domestic recommendations on a unified terminology of RC for diagnostic purposes and provide radiologists with a consensus methodological resource on the terminology, description and interpretation of RC imaging results. Materials and methods. Based on the analysis of recent domestic and international scientific and methodological literature on RC, the key terms used in the diagnosis and treatment planning of RC were selected, followed by a two-time online discussion of their interpretations by experts from the Russian Society of Radiologists and Therapeutic Radiation Oncologists, the Association of Oncologists of Russia and the Russian Association of Therapeutic Radiation Oncologists until reaching consensus (80%) of experts on all items. Terms for which there was no consensus were not included in the final list. Results. A list of anatomical, pathomorphological and clinical terms used in the diagnosis, staging and treatment planning of RC has been compiled and, based on expert consensus, their interpretation has been determined. Conclusion. A lexicon recommended in the description and formulation of the conclusion of diagnostic studies in patients with RC is proposed.
{"title":"Rectal Cancer Terminology: Consensus Agreement of a Working Group of Experts from POPP, AOR, and RATRO","authors":"P. Berezovskaya, A. Rubtsova, alentin E. Sinitsyn, V. Irina, Zarodnyuk, Nicolai V. Nudnov, Andrei V. Mishchenko, Yuliya L. Trubacheva, A. Bergen, Pavel, U. Grishko, Svetlana S. Balyasnikova, A. Dayneko, M. Malika, odzhibekova, Nataliya A. Rucheva, Igor E. Turin, I. Sergey, Achkasov, A. A. Nevolskikh, Sergey S. Gordeev, .. Droshneva","doi":"10.17816/dd529668","DOIUrl":"https://doi.org/10.17816/dd529668","url":null,"abstract":"Backgraund. Unified terminology is a necessary condition for successful interdisciplinary communication in oncology. The variety of anatomical, pathomorphological and clinical terms used in rectal cancer (RC) is often accompanied by their ambiguous interpretation both in domestic and foreign scientific literature. This not only complicates the interaction between specialists, but also makes it difficult to compare the results of RC treatment obtained in different medical institutions. \u0000Aim. Develop domestic recommendations on a unified terminology of RC for diagnostic purposes and provide radiologists with a consensus methodological resource on the terminology, description and interpretation of RC imaging results. \u0000Materials and methods. Based on the analysis of recent domestic and international scientific and methodological literature on RC, the key terms used in the diagnosis and treatment planning of RC were selected, followed by a two-time online discussion of their interpretations by experts from the Russian Society of Radiologists and Therapeutic Radiation Oncologists, the Association of Oncologists of Russia and the Russian Association of Therapeutic Radiation Oncologists until reaching consensus (80%) of experts on all items. Terms for which there was no consensus were not included in the final list. \u0000Results. A list of anatomical, pathomorphological and clinical terms used in the diagnosis, staging and treatment planning of RC has been compiled and, based on expert consensus, their interpretation has been determined. \u0000Conclusion. A lexicon recommended in the description and formulation of the conclusion of diagnostic studies in patients with RC is proposed.","PeriodicalId":34831,"journal":{"name":"Digital Diagnostics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41837362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Azhar M Kabdullina, Valentin E Sinitsyn, Raushan I Rakhimzhanova, Tairkhan B Dautov, Aigul Saduakassova, Baurzhan B Kaliyev, L. Bastarbekova
Aim: To investigate the frequency of complications after a tetralogy of Fallot (ToF) repair (rToF) in pediatric patients, as detected through computed tomography (CT). Methods: A retrospective analysis of 613 patients with ToF was carried out from October 2011 to June 2020. A total of 116 patients (69 male and 47 female), with complications after a rToF (as identified by CT), were included in this study. When rToF was performed, the patients average age ranged from 10 to 36 months (mean 12 months), average body weight was 21 kg, average height was 105.4 cm, and average body surface area (BSA) was 0.74 m2. The patients median age at the time of the CT examination was 17.5 years (age range: 736 years). Results: Of a total of 116 patients that exhibited complications after an rTOF, 49 had a pulmonary artery (PA) stenosis, 92 had a PA branch stenosis (56 of them of the left main PA branch (LPA), and 36 of them of the right main PA branch (RPA)), 8 had a right ventricular outflow tract (RVOT) stenosis, 32 had a ventricular septal defect, 1 had a shunt thrombosis, 12 had a postoperative deformation of the PA, 10 exhibited a marked right ventricular dilatation, 2 had an RVOT aneurysm, and 6 suffered from conduit calcification and stenosis. Moreover, there was a 6.5 times greater chance of developing an RPA stenosis in patients with an LPA stenosis (p 0.001). Conclusions: The most frequently CT-detected complications after a rToF were PA stenosis and PA branch stenosis. Patients with PA and PA branch stenosis exhibit no significant differences in terms of age, anthropometric parameters (height, weight, and BSA), and gender distribution in the presence or absence of different stenosis types (PA, RPA, or LPA). However, an RPA stenosis increases the chances of developing an LPA stenosis.
{"title":"Frequency of various cardiac complications in children with repaired tetralogy of Fallot identified, as identified by computer tomography","authors":"Azhar M Kabdullina, Valentin E Sinitsyn, Raushan I Rakhimzhanova, Tairkhan B Dautov, Aigul Saduakassova, Baurzhan B Kaliyev, L. Bastarbekova","doi":"10.17816/dd375285","DOIUrl":"https://doi.org/10.17816/dd375285","url":null,"abstract":"Aim: To investigate the frequency of complications after a tetralogy of Fallot (ToF) repair (rToF) in pediatric patients, as detected through computed tomography (CT). \u0000Methods: A retrospective analysis of 613 patients with ToF was carried out from October 2011 to June 2020. A total of 116 patients (69 male and 47 female), with complications after a rToF (as identified by CT), were included in this study. When rToF was performed, the patients average age ranged from 10 to 36 months (mean 12 months), average body weight was 21 kg, average height was 105.4 cm, and average body surface area (BSA) was 0.74 m2. The patients median age at the time of the CT examination was 17.5 years (age range: 736 years). \u0000Results: Of a total of 116 patients that exhibited complications after an rTOF, 49 had a pulmonary artery (PA) stenosis, 92 had a PA branch stenosis (56 of them of the left main PA branch (LPA), and 36 of them of the right main PA branch (RPA)), 8 had a right ventricular outflow tract (RVOT) stenosis, 32 had a ventricular septal defect, 1 had a shunt thrombosis, 12 had a postoperative deformation of the PA, 10 exhibited a marked right ventricular dilatation, 2 had an RVOT aneurysm, and 6 suffered from conduit calcification and stenosis. Moreover, there was a 6.5 times greater chance of developing an RPA stenosis in patients with an LPA stenosis (p 0.001). \u0000Conclusions: The most frequently CT-detected complications after a rToF were PA stenosis and PA branch stenosis. Patients with PA and PA branch stenosis exhibit no significant differences in terms of age, anthropometric parameters (height, weight, and BSA), and gender distribution in the presence or absence of different stenosis types (PA, RPA, or LPA). However, an RPA stenosis increases the chances of developing an LPA stenosis.","PeriodicalId":34831,"journal":{"name":"Digital Diagnostics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46665719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Valeriya Alekseevna Zarya, P. Gavrilov, M. Makogonova, Andrei Romanovich Kozak, A. Vishnevsky
This paper presents a clinical case with secondary developed ThYII-ThYIII vertebral spondylitis due to esophageal fistula. At the initial diagnosis, spondylitis was associated with spinal anesthesia, which was carried out 6 months before the onset of the disease, since there was a fistulous defect on the skin in the lumbar region. On this occasion, surgical interventions were performed three times in a surgical hospital at the place of residence. The data of endoscopic examination and the patient's complaints about the relationship between meals, the appearance of pain and the nature of the discharge from the fistula were not taken into account by doctors initially. With the help of an additional examination, including computed tomography of the esophagus with oral contrast and CT fistulography, the main diagnosis was esophageal fistula. Thoracic spondylitis was only a secondary complication
{"title":"Chronic esophageal fistula as a rare cause of secondary osteomyelitis of the thoracic spine","authors":"Valeriya Alekseevna Zarya, P. Gavrilov, M. Makogonova, Andrei Romanovich Kozak, A. Vishnevsky","doi":"10.17816/dd430128","DOIUrl":"https://doi.org/10.17816/dd430128","url":null,"abstract":"This paper presents a clinical case with secondary developed ThYII-ThYIII vertebral spondylitis due to esophageal fistula. At the initial diagnosis, spondylitis was associated with spinal anesthesia, which was carried out 6 months before the onset of the disease, since there was a fistulous defect on the skin in the lumbar region. On this occasion, surgical interventions were performed three times in a surgical hospital at the place of residence. The data of endoscopic examination and the patient's complaints about the relationship between meals, the appearance of pain and the nature of the discharge from the fistula were not taken into account by doctors initially. With the help of an additional examination, including computed tomography of the esophagus with oral contrast and CT fistulography, the main diagnosis was esophageal fistula. Thoracic spondylitis was only a secondary complication","PeriodicalId":34831,"journal":{"name":"Digital Diagnostics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44732503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. J. Hossain, A. Petraikin, A. Muraev, A. Danaev, D. Burenchev, A. Dolgalev, Y. Vasilev, Darya E. Sharova, Andrey Yu. Tikhmyanov, Sergey Y. Ivanov
Background: Cone beam computed tomography (CBCT) applied for diagnostics and planning various manipulations in the maxillofacial region, e.g. dental implantation. The advantages of this method are high spatial resolution, low radiation exposure, low cost. However, it has a significant drawback: the inability to determine the density of the jaw bone in Hounsfield Units (HU). Aims: To develop radiopaque templates with sets of X-ray density based on potassium hydrophosphate (PHP) and beta-tricalcium phosphate (betta-TCP), to study templates on various CBCT and multidetector computed tomography (MDCT) devices and to determine a cross-calibration algorithm for assessing the bone mineral density (BMD) of the jaw in HU. Materials and methods: BMD template consists microtubes (0.25 ml), PHP concentrations were set: 49.96; 99.98; 174.99; 349.99; 549.98 mg/ml, as well as a suspension of betta-TCP with an equivalent concentration of PHP 1506 mg/ml: simulate the types of bone density according to C.Mish. The study was carried out on 2 MDCT and 4 CBCT. Cross-calibration was referred on the "standard" MDCT1 mode 120 kV, 200 mA. Results: There was a significant scatter of the X-ray values (HU for MDCT and GV for CBCT) vs BMD; the slopes, bias and the shapes of the curves was differing. After cross-calibration, good comparability corresponding to the MDCT1 mode was shown. The median of the differences before cross-calibration was 160 relative units (HU, GV); after decreased by 10 times and amounted to 16 rel. units (p=0.000). The mean difference for CBCT was significantly higher (30 rel. units) than for MDCT (8 rel. units), p=0.024 Mann-Whitney test. Conclusions: The developed radiopaque template makes it possible to standardize densitometric indicators for CBCT and various MSCT modes, on average, the spread after cross-calibration is reduced by 10 times, which makes it possible to classify bone tissue in HU according to C. Mish.
{"title":"Bone mineral density radiopaque templates for cone beam computed tomography and multidetector computed tomography","authors":"S. J. Hossain, A. Petraikin, A. Muraev, A. Danaev, D. Burenchev, A. Dolgalev, Y. Vasilev, Darya E. Sharova, Andrey Yu. Tikhmyanov, Sergey Y. Ivanov","doi":"10.17816/dd501771","DOIUrl":"https://doi.org/10.17816/dd501771","url":null,"abstract":"Background: Cone beam computed tomography (CBCT) applied for diagnostics and planning various manipulations in the maxillofacial region, e.g. dental implantation. The advantages of this method are high spatial resolution, low radiation exposure, low cost. However, it has a significant drawback: the inability to determine the density of the jaw bone in Hounsfield Units (HU). \u0000 \u0000Aims: To develop radiopaque templates with sets of X-ray density based on potassium hydrophosphate (PHP) and beta-tricalcium phosphate (betta-TCP), to study templates on various CBCT and multidetector computed tomography (MDCT) devices and to determine a cross-calibration algorithm for assessing the bone mineral density (BMD) of the jaw in HU. \u0000Materials and methods: BMD template consists microtubes (0.25 ml), PHP concentrations were set: 49.96; 99.98; 174.99; 349.99; 549.98 mg/ml, as well as a suspension of betta-TCP with an equivalent concentration of PHP 1506 mg/ml: simulate the types of bone density according to C.Mish. The study was carried out on 2 MDCT and 4 CBCT. Cross-calibration was referred on the \"standard\" MDCT1 mode 120 kV, 200 mA. \u0000Results: There was a significant scatter of the X-ray values (HU for MDCT and GV for CBCT) vs BMD; the slopes, bias and the shapes of the curves was differing. After cross-calibration, good comparability corresponding to the MDCT1 mode was shown. The median of the differences before cross-calibration was 160 relative units (HU, GV); after decreased by 10 times and amounted to 16 rel. units (p=0.000). The mean difference for CBCT was significantly higher (30 rel. units) than for MDCT (8 rel. units), p=0.024 Mann-Whitney test. \u0000Conclusions: The developed radiopaque template makes it possible to standardize densitometric indicators for CBCT and various MSCT modes, on average, the spread after cross-calibration is reduced by 10 times, which makes it possible to classify bone tissue in HU according to C. Mish.","PeriodicalId":34831,"journal":{"name":"Digital Diagnostics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48462664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Zinchenko, Sergey Zayunchkovskiy, Sergey Konovalov, D. Sharova, Ekaterina S. Ahkmad, A. Vladzymyrskyy
The article presents the principles of the quality management system and the processes of organizations. The main attention is paid to the features of quality management systems of medical devices, the features of the quality management system of software as a medical device. The authors note the conditions when the quality management system becomes a tool for ensuring the sustainable development of the organization.
{"title":"QUALITY MANAGEMENT SYSTEM: A TOOL FOR THE DEVELOPMENT OF THE ORGANIZATION OR AN ADDITIONAL BURDEN?","authors":"V. Zinchenko, Sergey Zayunchkovskiy, Sergey Konovalov, D. Sharova, Ekaterina S. Ahkmad, A. Vladzymyrskyy","doi":"10.17816/dd514629","DOIUrl":"https://doi.org/10.17816/dd514629","url":null,"abstract":"The article presents the principles of the quality management system and the processes of organizations. The main attention is paid to the features of quality management systems of medical devices, the features of the quality management system of software as a medical device. The authors note the conditions when the quality management system becomes a tool for ensuring the sustainable development of the organization.","PeriodicalId":34831,"journal":{"name":"Digital Diagnostics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42557122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yurii A. Vasiliev, Anton Vyacheslavovich Vlazimirsky, O. Omelyanskaya, K. Arzamasov, S. Chetverikov, D. A. Rumyantsev, M. Zelenova
BACKGROUND: The global amount of investment in companies developing software based on artificial intelligence (AI) technologies for medical diagnostics was $80 million in 2016, $152 million in 2017 and is expected to continue to grow. Activity of software manufacturing companies should comply with existing clinical, bioethical, legal and methodological frameworks and standards. Both at the national and international levels, there are no uniform standards and protocols for testing and monitoring AI-based software. AIM: to develop a universal methodology for testing and monitoring AI-based software for medical diagnostics, aimed at improving its quality and implementing into practical healthcare. MATERIALS AND METHODS: During the analytical phase, a literature review was conducted on the PubMed and eLIBRARY databases. The practical stage included approbation of the developed methodology within the framework of the an Experiment on the use of innovative technologies in the field of computer vision for the analysis of medical images and further application in the health care system of the city of Moscow. RESULTS: A methodology for testing and monitoring AI-based software for medical diagnostics has been developed, aimed at improving its quality and introducing it into practical healthcare. The methodology consists of 7 stages: self-testing, functional testing, calibration testing, technological monitoring, clinical monitoring, feedback and refinement. CONCLUSION: Distinctive features of the methodology are: the cyclical stages of monitoring and software development, leading to continuous improvement of its quality, the presence of detailed requirements for the results of the software work, the participation of doctors in software evaluation. The methodology will allow both software developers to achieve high results and demonstrate achievements in various areas, and users to make an informed and confident choice among software that has passed an independent and comprehensive quality check.
{"title":"Methodology for testing and monitoring AI-based software for medical diagnostics","authors":"Yurii A. Vasiliev, Anton Vyacheslavovich Vlazimirsky, O. Omelyanskaya, K. Arzamasov, S. Chetverikov, D. A. Rumyantsev, M. Zelenova","doi":"10.17816/dd321971","DOIUrl":"https://doi.org/10.17816/dd321971","url":null,"abstract":"BACKGROUND: The global amount of investment in companies developing software based on artificial intelligence (AI) technologies for medical diagnostics was $80 million in 2016, $152 million in 2017 and is expected to continue to grow. Activity of software manufacturing companies should comply with existing clinical, bioethical, legal and methodological frameworks and standards. Both at the national and international levels, there are no uniform standards and protocols for testing and monitoring AI-based software. \u0000AIM: to develop a universal methodology for testing and monitoring AI-based software for medical diagnostics, aimed at improving its quality and implementing into practical healthcare. \u0000MATERIALS AND METHODS: During the analytical phase, a literature review was conducted on the PubMed and eLIBRARY databases. The practical stage included approbation of the developed methodology within the framework of the an Experiment on the use of innovative technologies in the field of computer vision for the analysis of medical images and further application in the health care system of the city of Moscow. \u0000RESULTS: A methodology for testing and monitoring AI-based software for medical diagnostics has been developed, aimed at improving its quality and introducing it into practical healthcare. The methodology consists of 7 stages: self-testing, functional testing, calibration testing, technological monitoring, clinical monitoring, feedback and refinement. \u0000CONCLUSION: Distinctive features of the methodology are: the cyclical stages of monitoring and software development, leading to continuous improvement of its quality, the presence of detailed requirements for the results of the software work, the participation of doctors in software evaluation. The methodology will allow both software developers to achieve high results and demonstrate achievements in various areas, and users to make an informed and confident choice among software that has passed an independent and comprehensive quality check.","PeriodicalId":34831,"journal":{"name":"Digital Diagnostics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47879070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：