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Rethinking Cancer Screening and Diagnosis During the Covid-19 Pandemic 重新思考Covid-19大流行期间的癌症筛查和诊断
Pub Date : 2020-12-30 DOI: 10.47363/jonrr/2020(1)110
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引用次数: 0
Hemangioma of Liver in a Patient with Neurofibromatosis Type I (Von Recklinghausen’s Disease) I型神经纤维瘤病(Von Recklinghausen病)患者肝脏血管瘤的研究
Pub Date : 2020-12-30 DOI: 10.47363/JONRR/2020(1)112
M. Waleed, W. Sadiq, Sanniyah Subhan
Case Presentation A 62 year old male presented to the hospital with abdominal pain and watery diarrhea since a week .he had 5 episodes in a day and the diarrhea was watery in consistency. He also complained of anorexia since the past month but no weight loss was documented. On examination he had dyspnea on exertion and his abdomen had guarding and was tender. His bowel sounds were positive. He smoked cigarette as well as hukka with a history of one pack per day for 25 years.No other comorbidities were present. He had pallor and neurofibromas all over his body with the largest being behind his left ear as shown in Figure: 1 and 2. His rest of the systemic examination was normal. His ultrasound showed a hemangioma in the left lobe of the liver measuring 4.4cmX4.3X4.9cm as shown in Figure: 3
男,62岁,1周以来以腹痛、水样腹泻就诊,一日5次,腹泻呈水样浓稠。自上个月以来,他还抱怨自己患有厌食症,但没有任何减肥记录。检查时,他用力时呼吸困难,腹部有压迫和压痛。他的肠道声音呈阳性。他吸香烟和胡卡,每天一包,有25年的历史。无其他合并症。他全身苍白,神经纤维瘤,最大的在左耳后面,如图1和2所示。其余全身检查正常。超声示肝左叶血管瘤,尺寸为4.4cmX4.3X4.9cm,如图3所示
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引用次数: 0
The Emirates Oncology Task Force Clinical Practice Guideline on Screening for SARS-CoV-2 in Asymptomatic Adult Cancer Patients Prior to Anti-Cancer Therapy (Preprint) 阿联酋肿瘤工作组无症状成年癌症患者抗癌治疗前SARS-CoV-2筛查临床实践指南(预印本)
Pub Date : 2020-10-15 DOI: 10.2196/preprints.25026
H. Al-Shamsi
BACKGROUND Cancer care during this pandemic is challenging given the competing risks of death from cancer versus death or serious complications from SARS- CoV-2 infection, and the likely higher lethality of COVID-19 in immunocompromised patients. Question remains on serial screening for SARS-CoV-2 in asymptomatic adult cancer patients prior to anti-cancer therapy during the COVID-19 pandemic. OBJECTIVE Formulate a consensus guideline statement to guide practicing physicians METHODS We conducted a systematic review to formulate a consensus statement to guide the practising oncologists RESULTS Most of the current guidelines recommend RT-PCR SARS-CoV-2 testing of asymptomatic patients prior to initiating and during the anti-cancer therapy despite the lack of robust evidence. We suggested the following: If screening is indicated in adult cancer patients, we recommend using RT-PCR over serum antibody or serum antigen for adult cancer patients; we also recommend assessing the risk of exposure to and infection from SARS-CoV-2 prior to each anti-cancer cycle, to consider SARS-CoV-2 in asymptomatic adult cancer patients prior to anti-cancer therapy in high risk groups : highly cytotoxic chemotherapy with potential profound neutropenia based on the physician’s risk assessment of the chemotherapy , stem cell transplantation. For asymptomatic intermediate-high risk cancer patients, we suggest performing RT-PCR 48-72 hours prior to initiating any anti-cancer therapy. For asymptomatic low-risk cancer patients, we suggest not to routinely screen prior to initiating any anti-cancer therapy (weak recommendation, low quality evidence). CONCLUSIONS SARS-CoV-2 screening might be indicated with higher certainty to certain cancer risk groups. There remains a need for prospective trials to assess this intervention, and the outcome of such intervention. Current recommendations may change based on new and emerging evidence.
背景:鉴于癌症死亡与SARS- CoV-2感染的死亡或严重并发症的风险相互竞争,以及COVID-19在免疫功能低下患者中可能更高的致死率,本次大流行期间的癌症护理具有挑战性。在COVID-19大流行期间,对无症状成年癌症患者进行抗癌治疗前的SARS-CoV-2系列筛查仍存在疑问。目的制定指导执业医师的共识性指南声明方法通过系统评价,制定指导执业肿瘤科医师的共识声明结果尽管缺乏强有力的证据,但目前大多数指南都建议在无症状患者开始抗癌治疗前和治疗过程中进行RT-PCR SARS-CoV-2检测。我们的建议如下:如果成人癌症患者需要筛查,我们建议对成人癌症患者使用RT-PCR检测血清抗体或血清抗原;我们还建议在每个抗癌周期之前评估SARS-CoV-2暴露和感染的风险,在无症状成人癌症患者的高风险群体中,在进行抗癌治疗之前考虑SARS-CoV-2:基于医生对化疗、干细胞移植的风险评估,高细胞毒性化疗伴有潜在的深度中性粒细胞减少症。对于无症状的中高危癌症患者,我们建议在开始任何抗癌治疗前48-72小时进行RT-PCR。对于无症状的低风险癌症患者,我们建议在开始任何抗癌治疗前不要进行常规筛查(弱推荐,低质量证据)。结论SARS-CoV-2筛查对某些癌症危险人群具有较高的确定性。仍然需要前瞻性试验来评估这种干预措施及其结果。目前的建议可能会根据新的和正在出现的证据而改变。
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引用次数: 0
Reducing Stigma of Cancer in Asia–An Important Strategy for Cancer Control 减少亚洲对癌症的耻辱感——癌症控制的重要策略
Pub Date : 2020-06-30 DOI: 10.47363/JONRR/2020(1)101
L. Yim
Half the global burden of cancer is in Asia, where 60 percent of the world population live. Ageing society, growing populations, lifestyle and socioeconomic changes have contributed to a steep rise in cancer incidences. The emerging cancer burden across Asia call for balanced investments in public and professional awareness and political recognition of cancer as a public health problem. Early detection and cancer prevention leads to both better health outcomes and better cost-savings of treatment costs. Although evolving cancer health services need to be stepped up to strengthen cancer healthcare infrastructure to improve equitable access to services, more work must be conducted in the community to address the entrenched stigma of cancer and caused a shift towards a more positive perception to help address cancer in Asia.
全球癌症负担的一半在亚洲,而亚洲人口占世界人口的60%。老龄化社会、人口增长、生活方式和社会经济变化导致癌症发病率急剧上升。亚洲各地正在出现的癌症负担要求平衡投资,提高公众和专业意识,并从政治上认识到癌症是一个公共卫生问题。早期发现和预防癌症既能带来更好的健康结果,也能更好地节省治疗费用。虽然需要加强不断发展的癌症卫生服务,以加强癌症卫生保健基础设施,以改善公平获得服务的机会,但必须在社区开展更多工作,以解决对癌症根深蒂固的污名,并促使人们转向更积极的看法,以帮助亚洲解决癌症问题。
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引用次数: 2
Dysgraphy and Functional Rehabilitation 书写障碍与功能康复
Pub Date : 2020-06-30 DOI: 10.47363/JONRR/2020(1)105
D. Furnari, Physiotherapist Osteopath-Psychomotorist Grafomototherapist – Kine Researcher
Learning to write requires a good functional, motor, intellectual and levelaffective and presupposes the knowledge and appropriate use of language.A complex of skills that the subject does not always possess and which makes him vulnerable to school failure.The state of failure can provoke inattention, demotivation, behavioral disorders withpossible manifestations of aggression or apathy.A problem, as we can see, which is not indifferent that worries teachers and parents, who mustbe directed to find suitable programs to face difficulties, to formulate and definehelpful answers. The activity of writing is a learning, but before being a means ofintellectual evolution, this learning is in close relationship with neuropercective behaviors-motor.We know that language is prior to graphism and although we do not dwell on this workon language, let's not forget that learning to read and write are based onan expressive language where sound succession and sound quality are importantissued.In other words, before learning to read and write, the child must be helpedo use as rich a language as possible. In fact, writing and reading are before everything, the means of communication and personal expression.
学习写作需要良好的功能、运动、智力和情感水平,并以语言的知识和适当使用为前提。一个复杂的技能,他并不总是拥有,这使他容易在学校失败。失败的状态会引起注意力不集中,失去动力,行为障碍,可能表现为攻击或冷漠。正如我们所看到的,这是一个困扰着教师和家长的问题,必须指导他们找到合适的方案来面对困难,制定和确定有用的答案。写作活动是一种学习,但在成为智力进化的手段之前,这种学习与神经感知行为-运动密切相关。我们知道,语言先于文字,虽然我们不细想这种工作语言,但我们不要忘记,学习阅读和写作是基于一种表达性语言,其中声音的连续性和音质是很重要的。换句话说,在学习读写之前,必须帮助孩子尽可能多地使用丰富的语言。事实上,写作和阅读是最重要的,是沟通和个人表达的手段。
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引用次数: 0
Colon Screening In the Community–A Community Program and Lesson Learnt 社区结肠筛检:社区计划及经验教训
Pub Date : 2020-06-30 DOI: 10.47363/JONRR/2020(1)102
L. Yim
Colon-cancer awareness talk, with free faecal immunochemical (FIT) kit conducted by volunteers for the residents living near a cancer community centre in Petaling Jaya, an urban city with a multi-ethnic population. The aim of this report is to present and discuss the outcome of a community screening talk with free FIT kit. 295 healthy individuals who met inclusion criteria consented to take part in the pilot, only 62 percent (184/295) showed up for the intervention. 11.7 percent (n=19) were tested positives but only 9 went for a follow up colonoscopy, and the remainder were still waiting for a colonoscopy after 6 months. Cancer is still a fearful topic despite better treatment, and screening tests offered beneficial outcomes for early detection and cure, but the uptakes for the screening with awareness talk at a community centre on weekends is slow. Better study with outcome measures and qualitative study to explore barriers and facilitators are needed.
在百打灵查亚,一个多民族人口的城市,志愿者为居住在癌症社区中心附近的居民进行了结肠癌意识讲座,并提供免费的粪便免疫化学(FIT)试剂盒。本报告的目的是介绍和讨论免费FIT工具包的社区筛查讲座的结果。295名符合纳入标准的健康个体同意参加试验,只有62%(184/295)的人参加了干预。11.7% (n=19)的人检测呈阳性,但只有9人进行了结肠镜检查,其余的人在6个月后仍在等待结肠镜检查。尽管有了更好的治疗方法,癌症仍然是一个令人恐惧的话题,筛查测试为早期发现和治疗提供了有益的结果,但周末在社区中心举行的宣传活动中接受筛查的速度很慢。需要更好地研究结果测量和定性研究,以探索障碍和促进因素。
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引用次数: 0
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Journal of Oncology Research Review & Reports
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