Pub Date : 2020-12-30DOI: 10.47363/jonrr/2020(1)110
{"title":"Rethinking Cancer Screening and Diagnosis During the Covid-19 Pandemic","authors":"","doi":"10.47363/jonrr/2020(1)110","DOIUrl":"https://doi.org/10.47363/jonrr/2020(1)110","url":null,"abstract":"","PeriodicalId":351114,"journal":{"name":"Journal of Oncology Research Review & Reports","volume":"242 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124669146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-30DOI: 10.47363/JONRR/2020(1)112
M. Waleed, W. Sadiq, Sanniyah Subhan
Case Presentation A 62 year old male presented to the hospital with abdominal pain and watery diarrhea since a week .he had 5 episodes in a day and the diarrhea was watery in consistency. He also complained of anorexia since the past month but no weight loss was documented. On examination he had dyspnea on exertion and his abdomen had guarding and was tender. His bowel sounds were positive. He smoked cigarette as well as hukka with a history of one pack per day for 25 years.No other comorbidities were present. He had pallor and neurofibromas all over his body with the largest being behind his left ear as shown in Figure: 1 and 2. His rest of the systemic examination was normal. His ultrasound showed a hemangioma in the left lobe of the liver measuring 4.4cmX4.3X4.9cm as shown in Figure: 3
{"title":"Hemangioma of Liver in a Patient with Neurofibromatosis Type I (Von Recklinghausen’s Disease)","authors":"M. Waleed, W. Sadiq, Sanniyah Subhan","doi":"10.47363/JONRR/2020(1)112","DOIUrl":"https://doi.org/10.47363/JONRR/2020(1)112","url":null,"abstract":"Case Presentation A 62 year old male presented to the hospital with abdominal pain and watery diarrhea since a week .he had 5 episodes in a day and the diarrhea was watery in consistency. He also complained of anorexia since the past month but no weight loss was documented. On examination he had dyspnea on exertion and his abdomen had guarding and was tender. His bowel sounds were positive. He smoked cigarette as well as hukka with a history of one pack per day for 25 years.No other comorbidities were present. He had pallor and neurofibromas all over his body with the largest being behind his left ear as shown in Figure: 1 and 2. His rest of the systemic examination was normal. His ultrasound showed a hemangioma in the left lobe of the liver measuring 4.4cmX4.3X4.9cm as shown in Figure: 3","PeriodicalId":351114,"journal":{"name":"Journal of Oncology Research Review & Reports","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133766670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUND Cancer care during this pandemic is challenging given the competing risks of death from cancer versus death or serious complications from SARS- CoV-2 infection, and the likely higher lethality of COVID-19 in immunocompromised patients. Question remains on serial screening for SARS-CoV-2 in asymptomatic adult cancer patients prior to anti-cancer therapy during the COVID-19 pandemic. OBJECTIVE Formulate a consensus guideline statement to guide practicing physicians METHODS We conducted a systematic review to formulate a consensus statement to guide the practising oncologists RESULTS Most of the current guidelines recommend RT-PCR SARS-CoV-2 testing of asymptomatic patients prior to initiating and during the anti-cancer therapy despite the lack of robust evidence. We suggested the following: If screening is indicated in adult cancer patients, we recommend using RT-PCR over serum antibody or serum antigen for adult cancer patients; we also recommend assessing the risk of exposure to and infection from SARS-CoV-2 prior to each anti-cancer cycle, to consider SARS-CoV-2 in asymptomatic adult cancer patients prior to anti-cancer therapy in high risk groups : highly cytotoxic chemotherapy with potential profound neutropenia based on the physician’s risk assessment of the chemotherapy , stem cell transplantation. For asymptomatic intermediate-high risk cancer patients, we suggest performing RT-PCR 48-72 hours prior to initiating any anti-cancer therapy. For asymptomatic low-risk cancer patients, we suggest not to routinely screen prior to initiating any anti-cancer therapy (weak recommendation, low quality evidence). CONCLUSIONS SARS-CoV-2 screening might be indicated with higher certainty to certain cancer risk groups. There remains a need for prospective trials to assess this intervention, and the outcome of such intervention. Current recommendations may change based on new and emerging evidence.
{"title":"The Emirates Oncology Task Force Clinical Practice Guideline on Screening for SARS-CoV-2 in Asymptomatic Adult Cancer Patients Prior to Anti-Cancer Therapy (Preprint)","authors":"H. Al-Shamsi","doi":"10.2196/preprints.25026","DOIUrl":"https://doi.org/10.2196/preprints.25026","url":null,"abstract":"\u0000 BACKGROUND\u0000 Cancer care during this pandemic is challenging given the competing risks of death from cancer versus death or serious complications from SARS- CoV-2 infection, and the likely higher lethality of COVID-19 in immunocompromised patients. Question remains on serial screening for SARS-CoV-2 in asymptomatic adult cancer patients prior to anti-cancer therapy during the COVID-19 pandemic.\u0000 \u0000 \u0000 OBJECTIVE\u0000 Formulate a consensus guideline statement to guide practicing physicians\u0000 \u0000 \u0000 METHODS\u0000 We conducted a systematic review to formulate a consensus statement to guide the practising oncologists\u0000 \u0000 \u0000 RESULTS\u0000 Most of the current guidelines recommend RT-PCR SARS-CoV-2 testing of asymptomatic patients prior to initiating and during the anti-cancer therapy despite the lack of robust evidence. \u0000We suggested the following: If screening is indicated in adult cancer patients, we recommend using RT-PCR over serum antibody or serum antigen for adult cancer patients; we also recommend assessing the risk of exposure to and infection from SARS-CoV-2 prior to each anti-cancer cycle, to consider SARS-CoV-2 in asymptomatic adult cancer patients prior to anti-cancer therapy in high risk groups : highly cytotoxic chemotherapy with potential profound neutropenia based on the physician’s risk assessment of the chemotherapy , stem cell transplantation. For asymptomatic intermediate-high risk cancer patients, we suggest performing RT-PCR 48-72 hours prior to initiating any anti-cancer therapy. For asymptomatic low-risk cancer patients, we suggest not to routinely screen prior to initiating any anti-cancer therapy (weak recommendation, low quality evidence).\u0000 \u0000 \u0000 CONCLUSIONS\u0000 SARS-CoV-2 screening might be indicated with higher certainty to certain cancer risk groups. There remains a need for prospective trials to assess this intervention, and the outcome of such intervention. Current recommendations may change based on new and emerging evidence.\u0000","PeriodicalId":351114,"journal":{"name":"Journal of Oncology Research Review & Reports","volume":"186 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134646543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-06-30DOI: 10.47363/JONRR/2020(1)101
L. Yim
Half the global burden of cancer is in Asia, where 60 percent of the world population live. Ageing society, growing populations, lifestyle and socioeconomic changes have contributed to a steep rise in cancer incidences. The emerging cancer burden across Asia call for balanced investments in public and professional awareness and political recognition of cancer as a public health problem. Early detection and cancer prevention leads to both better health outcomes and better cost-savings of treatment costs. Although evolving cancer health services need to be stepped up to strengthen cancer healthcare infrastructure to improve equitable access to services, more work must be conducted in the community to address the entrenched stigma of cancer and caused a shift towards a more positive perception to help address cancer in Asia.
{"title":"Reducing Stigma of Cancer in Asia–An Important Strategy for Cancer Control","authors":"L. Yim","doi":"10.47363/JONRR/2020(1)101","DOIUrl":"https://doi.org/10.47363/JONRR/2020(1)101","url":null,"abstract":"Half the global burden of cancer is in Asia, where 60 percent of the world population live. Ageing society, growing populations, lifestyle and socioeconomic changes have contributed to a steep rise in cancer incidences. The emerging cancer burden across Asia call for balanced investments in public and professional awareness and political recognition of cancer as a public health problem. Early detection and cancer prevention leads to both better health outcomes and better cost-savings of treatment costs. Although evolving cancer health services need to be stepped up to strengthen cancer healthcare infrastructure to improve equitable access to services, more work must be conducted in the community to address the entrenched stigma of cancer and caused a shift towards a more positive perception to help address cancer in Asia.","PeriodicalId":351114,"journal":{"name":"Journal of Oncology Research Review & Reports","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125277480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-06-30DOI: 10.47363/JONRR/2020(1)105
D. Furnari, Physiotherapist Osteopath-Psychomotorist Grafomototherapist – Kine Researcher
Learning to write requires a good functional, motor, intellectual and levelaffective and presupposes the knowledge and appropriate use of language.A complex of skills that the subject does not always possess and which makes him vulnerable to school failure.The state of failure can provoke inattention, demotivation, behavioral disorders withpossible manifestations of aggression or apathy.A problem, as we can see, which is not indifferent that worries teachers and parents, who mustbe directed to find suitable programs to face difficulties, to formulate and definehelpful answers. The activity of writing is a learning, but before being a means ofintellectual evolution, this learning is in close relationship with neuropercective behaviors-motor.We know that language is prior to graphism and although we do not dwell on this workon language, let's not forget that learning to read and write are based onan expressive language where sound succession and sound quality are importantissued.In other words, before learning to read and write, the child must be helpedo use as rich a language as possible. In fact, writing and reading are before everything, the means of communication and personal expression.
{"title":"Dysgraphy and Functional Rehabilitation","authors":"D. Furnari, Physiotherapist Osteopath-Psychomotorist Grafomototherapist – Kine Researcher","doi":"10.47363/JONRR/2020(1)105","DOIUrl":"https://doi.org/10.47363/JONRR/2020(1)105","url":null,"abstract":"Learning to write requires a good functional, motor, intellectual and levelaffective and presupposes the knowledge and appropriate use of language.A complex of skills that the subject does not always possess and which makes him vulnerable \u0000to school failure.The state of failure can provoke inattention, demotivation, behavioral disorders withpossible manifestations of aggression or apathy.A problem, as we can see, which is not indifferent that worries teachers and parents, who mustbe directed to find suitable programs to face difficulties, to formulate and definehelpful answers. The activity of writing is a learning, but before being a means ofintellectual evolution, this learning is in close relationship with neuropercective behaviors-motor.We know that language is prior to graphism and although we do not dwell on this workon language, let's not forget that learning to read and write are based onan expressive language where sound succession and sound quality are importantissued.In other words, before learning to read and write, the child must be helpedo use as rich a language as possible. In fact, writing and reading are before \u0000everything, the means of communication and personal expression.","PeriodicalId":351114,"journal":{"name":"Journal of Oncology Research Review & Reports","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129515386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-06-30DOI: 10.47363/JONRR/2020(1)102
L. Yim
Colon-cancer awareness talk, with free faecal immunochemical (FIT) kit conducted by volunteers for the residents living near a cancer community centre in Petaling Jaya, an urban city with a multi-ethnic population. The aim of this report is to present and discuss the outcome of a community screening talk with free FIT kit. 295 healthy individuals who met inclusion criteria consented to take part in the pilot, only 62 percent (184/295) showed up for the intervention. 11.7 percent (n=19) were tested positives but only 9 went for a follow up colonoscopy, and the remainder were still waiting for a colonoscopy after 6 months. Cancer is still a fearful topic despite better treatment, and screening tests offered beneficial outcomes for early detection and cure, but the uptakes for the screening with awareness talk at a community centre on weekends is slow. Better study with outcome measures and qualitative study to explore barriers and facilitators are needed.
{"title":"Colon Screening In the Community–A Community Program and Lesson Learnt","authors":"L. Yim","doi":"10.47363/JONRR/2020(1)102","DOIUrl":"https://doi.org/10.47363/JONRR/2020(1)102","url":null,"abstract":"Colon-cancer awareness talk, with free faecal immunochemical (FIT) kit conducted by volunteers for the residents living near a cancer community centre in Petaling Jaya, an urban city with a multi-ethnic population. The aim of this report is to present and discuss the outcome of a community screening talk with free FIT kit. 295 healthy individuals who met inclusion criteria consented to take part in the pilot, only 62 percent (184/295) showed up for the intervention. 11.7 percent (n=19) were tested positives but only 9 went for a follow up colonoscopy, and the remainder were still waiting for a colonoscopy after 6 months. Cancer is still a fearful topic despite better treatment, and screening tests offered beneficial outcomes for early detection and cure, but the uptakes for the screening with awareness talk at a community centre on weekends is slow. Better study with outcome measures and qualitative study to explore barriers and facilitators are needed.","PeriodicalId":351114,"journal":{"name":"Journal of Oncology Research Review & Reports","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122469094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}